Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_017_N24
(963 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q10348|YDA6_SCHPO Putative endonuclease C1F12.06c 105 2e-22
sp|O66824|NFI_AQUAE Endonuclease V (Deoxyinosine 3'endonucl... 82 3e-15
sp|Q6HGE0|NFI_BACHK Endonuclease V (Deoxyinosine 3'endonucl... 78 3e-14
sp|P96724|NFI_BACSU Endonuclease V (Deoxyinosine 3'endonucl... 77 7e-14
sp|P52887|ALG8_CAEEL Probable dolichyl pyrophosphate Glc1Ma... 76 2e-13
sp|Q6MDK2|NFI_PARUW Endonuclease V (Deoxyinosine 3'endonucl... 75 4e-13
sp|Q8YPV5|NFI_ANASP Endonuclease V (Deoxyinosine 3'endonucl... 75 4e-13
sp|Q97M37|NFI_CLOAB Endonuclease V (Deoxyinosine 3'endonucl... 72 2e-12
sp|O30108|NFI_ARCFU Endonuclease V (Deoxyinosine 3'endonucl... 70 9e-12
sp|Q8ZYP2|NFI_PYRAE Endonuclease V (Deoxyinosine 3'endonucl... 69 2e-11
>sp|Q10348|YDA6_SCHPO Putative endonuclease C1F12.06c
Length = 252
Score = 105 bits (261), Expect = 2e-22
Identities = 97/292 (33%), Positives = 144/292 (49%), Gaps = 16/292 (5%)
Frame = +2
Query: 56 IRNMNNPDKSIIEIWKTKQLYLKELLILDNVESWQEELNHKIDDMNDLIIPSNLKLIGGI 235
+ N N DK + IW+ +Q+ LK +L +L K +N++ + + G+
Sbjct: 1 MNNDNLHDK--LTIWRQQQIELKGML----------QLIPKFQSLNEI------RYVVGL 42
Query: 236 DISFDKSNNNLACVCFVVIDSCTKKLVRK-HEKIVSIIEPYIVNYLAFRECEHMVGTIKE 412
DISFDKS+ A V+ D + ++ K + I + E Y+ +L+FRE IK
Sbjct: 43 DISFDKSSPK-AVSALVIYDLEQRMIIYKDYLCIEKLEEDYVPGFLSFRE-------IKW 94
Query: 413 FLVLYPEMKPQ----VILVDGNGVYHTMGFGSACQLGVRLEQEGIDIPTVGVAKNYLQLH 580
+L L + Q +ILVDGNGV H +GFG AC LGV L ++P VGVAKNYL
Sbjct: 95 YLPLLNHIPHQFRIDIILVDGNGVLHPVGFGLACHLGVLL-----NLPVVGVAKNYLHCV 149
Query: 581 GMPS-----REELK----EKITDHMIDGSEILLDLFLDEESNAICTVRRCDKSNLSKDVN 733
G+ RE LK +K TDH I I ++S+ I SN + V
Sbjct: 150 GLTESLDAHRETLKKHVLKKTTDHPILIHSI-------DQSSEILGAAVWTSSNSKRPV- 201
Query: 734 KLGKLAFISAGHRITLKTAVNIVRICSK--CRMPEPILLADHLAKNFLEKRK 883
++S G+++ L+ ++ +V+ CS R+PEPI AD AK L + K
Sbjct: 202 ------YVSIGNQMNLEQSIQLVQKCSSSHSRVPEPIRQADIYAKFVLSQSK 247
>sp|O66824|NFI_AQUAE Endonuclease V (Deoxyinosine 3'endonuclease) (Deoxyribonuclease V)
(DNase V)
Length = 220
Score = 81.6 bits (200), Expect = 3e-15
Identities = 79/245 (32%), Positives = 119/245 (48%), Gaps = 4/245 (1%)
Frame = +2
Query: 134 ILDNVESWQEELNHKIDDMNDLIIPSNLKLIGGIDISFDKSNNN--LACVCFVVIDSCTK 307
+L+ ++ Q E K+ +D ++ IGG+D++F+K N N A VV++ T
Sbjct: 3 LLEKLKKIQLECAKKVIARDDF---EKVETIGGMDLTFEKINENPTRAWASLVVVELKTL 59
Query: 308 KLVRKHEKIVSIIEPYIVNYLAFRECEHMVGTIKEFLVLYP--EMKPQVILVDGNGVYHT 481
K V +H + PYI +LAFRE + L LY ++KP V +DG G+ H
Sbjct: 60 KPVYQHVVKDIVDFPYIPTFLAFREMPLL-------LKLYETAKVKPDVYFIDGQGIAHP 112
Query: 482 MGFGSACQLGVRLEQEGIDIPTVGVAKNYLQLHGMPSREELKEKITDHMIDGSEILLDLF 661
G G A GV + TVGVAK+ +L G ++E ++ GS +
Sbjct: 113 RGCGIASHFGVETGE-----VTVGVAKS--KLFGY-AKEPAPQR-------GSY----TY 153
Query: 662 LDEESNAICTVRRCDKSNLSKDVNKLGKLAFISAGHRITLKTAVNIVRICSKCRMPEPIL 841
L + I V R K N + ++S GHRI+LKTA+++V SK R+PEP
Sbjct: 154 LKYKGKIIGAVVR-TKDNTAP--------VYVSVGHRISLKTAIDLVLKTSKYRVPEPTR 204
Query: 842 LADHL 856
LA +L
Sbjct: 205 LAHNL 209
>sp|Q6HGE0|NFI_BACHK Endonuclease V (Deoxyinosine 3'endonuclease) (Deoxyribonuclease V)
(DNase V)
Length = 235
Score = 78.2 bits (191), Expect = 3e-14
Identities = 71/247 (28%), Positives = 109/247 (44%), Gaps = 5/247 (2%)
Frame = +2
Query: 125 ELLILDNVESWQEELNHKIDDMNDLIIPSNLKLIGGIDISFDKSNNN-LACVCFVVIDSC 301
E ++ Q EL+ +I N+ I ++ I G+D+++ N C V+ID
Sbjct: 9 EKKLIQEFSKIQSELSPRIKLENNFQI-EEIQFIAGVDLAYWNVNKTKYGTCCIVIIDYG 67
Query: 302 TKKLVRKHEKIVSIIEPYIVNYLAFRECEHMVGTIKEFLVLYPEMKPQVILVDGNGVYHT 481
TK++V K I PYI +LAFRE ++ +K+ +P + DGNG H
Sbjct: 68 TKEVVEKVYSYGEIPIPYIPGFLAFRELPLIIEAVKKL-----TKQPDIYFFDGNGYLHY 122
Query: 482 MGFGSACQLGVRLEQEGIDIPTVGVAKNYLQLHGMP--SREELKEKITDHMIDGSEILLD 655
G A L + PT+GVAK+YL++ + E LK TD +I+
Sbjct: 123 RHMGIATHASFLLNK-----PTIGVAKSYLKIRDVDFIMPENLKGSYTDIVINNEVYGRT 177
Query: 656 LFLDEESNAICTVRRCDKSNLSKDVNKLGKLAFISAGHRITLKTAVNIVRIC--SKCRMP 829
L +K+V K F+S G+ I L T+ IV C ++ R+P
Sbjct: 178 L------------------RTTKNV----KPIFVSCGNWIDLDTSTEIVMNCINNESRLP 215
Query: 830 EPILLAD 850
P+ LAD
Sbjct: 216 IPVRLAD 222
>sp|P96724|NFI_BACSU Endonuclease V (Deoxyinosine 3'endonuclease) (Deoxyribonuclease V)
(DNase V)
Length = 238
Score = 77.0 bits (188), Expect = 7e-14
Identities = 67/246 (27%), Positives = 113/246 (45%), Gaps = 6/246 (2%)
Frame = +2
Query: 158 QEELNHKIDDMNDLIIPSNLKLIGGIDISF-DKSNNNLACVCFVVIDSCTKKLVRKHEKI 334
Q L ++I+ ++ I P ++ G+D+++ ++ C +VID+ TK+++ K +
Sbjct: 21 QFNLKNRIN-LSPTIHPDSINTGAGVDLAYWEQDGEPYGVCCIIVIDADTKEVIEKVHSM 79
Query: 335 VSIIEPYIVNYLAFRECEHMVGTIKEFLVLYPEMKPQVILVDGNGVYHTMGFGSACQLGV 514
I PY+ +LAFRE ++ K+ E +P V L DGNG H G A
Sbjct: 80 GRISVPYVSGFLAFRELPLIIEAAKKL-----ETEPDVFLFDGNGYLHYNHMGVATHAAF 134
Query: 515 RLEQEGIDIPTVGVAKNYLQLHGMPSREELKEKITDHMIDGSEILLDLFLDEESNAICTV 694
L + PT+G+AK YL++ G + +T + G+ D+ +D E
Sbjct: 135 FLGK-----PTIGIAKTYLKIKGC-------DFVTPEIEVGA--YTDIIIDGEVYGRALR 180
Query: 695 RRCDKSNLSKDVNKLGKLAFISAGHRITLKTAVNIVR--ICSKCRMPEPILLAD---HLA 859
R D K F+S G+ I L ++ I I + R+P P+ LAD H+
Sbjct: 181 TRRDV-----------KPIFLSCGNYIDLDSSYQITMSLINQESRLPIPVRLADLETHVL 229
Query: 860 KNFLEK 877
+ F +K
Sbjct: 230 RTFYQK 235
>sp|P52887|ALG8_CAEEL Probable dolichyl pyrophosphate Glc1Man9GlcNAc2
alpha-1,3-glucosyltransferase
(Dolichyl-P-Glc:Glc1Man9GlcNAc2-PP-dolichyl
glucosyltransferase)
Length = 758
Score = 75.9 bits (185), Expect = 2e-13
Identities = 58/166 (34%), Positives = 81/166 (48%), Gaps = 1/166 (0%)
Frame = +2
Query: 86 IIEIWKTKQL-YLKELLILDNVESWQEELNHKIDDMNDLIIPSNLKLIGGIDISFDKSNN 262
I EIW K ++E LI D+ S Q ++D++D+ KL+ GID S K N+
Sbjct: 501 IFEIWWAKATCQIRERLIRDSTYSVQA-----VEDLDDV------KLVAGIDTSAAKLNS 549
Query: 263 NLACVCFVVIDSCTKKLVRKHEKIVSIIEPYIVNYLAFRECEHMVGTIKEFLVLYPEMKP 442
++ + K V + PYI YLA RE E M +K + PE++P
Sbjct: 550 DMVYISVSFWTYPDLKHVATISDTRMLELPYIPQYLAVREAEVMADFLKSVITERPELRP 609
Query: 443 QVILVDGNGVYHTMGFGSACQLGVRLEQEGIDIPTVGVAKNYLQLH 580
VIL DG G +H+ G G AC +G I ++GVAKN L LH
Sbjct: 610 DVILCDGFGEFHSRGCGMACHVGAL-----SGIASIGVAKN-LTLH 649
>sp|Q6MDK2|NFI_PARUW Endonuclease V (Deoxyinosine 3'endonuclease) (Deoxyribonuclease V)
(DNase V)
Length = 235
Score = 74.7 bits (182), Expect = 4e-13
Identities = 78/250 (31%), Positives = 116/250 (46%), Gaps = 6/250 (2%)
Frame = +2
Query: 158 QEELNHKIDDMNDLIIPSNLKLIGGIDIS---FDKSNNNLACVCFVVIDSCTKKLVRKHE 328
Q+EL ++I ++ P + GG+D+S FD A +++DS K L +
Sbjct: 24 QKELANRICLEDEFNTP---EFFGGMDVSNNLFDPKQIIYATA--ILLDS--KMLSVQFH 76
Query: 329 KIVSIIE--PYIVNYLAFRECEHMVGTIKEFLVLYPEMKPQVILVDGNGVYHTMGFGSAC 502
VS + PYI +L FRE ++ ++ L P +I VDG G+ H G A
Sbjct: 77 NSVSQRQTFPYIPGFLGFREAPALIDALESLPKL-----PDMIFVDGQGISHPRRLGIAS 131
Query: 503 QLGVRLEQEGIDIPTVGVAKNYLQLHGMPSREELKEKITDHMIDGSEILLDLFLDEESNA 682
+GV ++IPT+GVAKN L G P +++L + D+ + L + E
Sbjct: 132 HIGVL-----VNIPTIGVAKNIL--FGEP-KKDLGSCVGDY------VFLYAYGKEIGAL 177
Query: 683 ICTVRRCDKSNLSKDVNKLGKLAFISAGHRITLKTAVNIVRICSK-CRMPEPILLADHLA 859
+ T RC K IS GHR++L+TA+ V C K R+PEP A HLA
Sbjct: 178 VRTKLRC-------------KPLIISTGHRVSLRTAIEYVLNCVKGYRLPEPTRQA-HLA 223
Query: 860 KNFLEKRKNA 889
N K+ A
Sbjct: 224 ANAFRKQSQA 233
>sp|Q8YPV5|NFI_ANASP Endonuclease V (Deoxyinosine 3'endonuclease) (Deoxyribonuclease V)
(DNase V)
Length = 221
Score = 74.7 bits (182), Expect = 4e-13
Identities = 68/249 (27%), Positives = 117/249 (46%), Gaps = 4/249 (1%)
Frame = +2
Query: 131 LILDNVESWQEELNHKIDDMNDLIIPSNLKLIGGIDISFDKSNNNLACVCFVVIDSCTKK 310
L ++ + QEEL H++ + P ++ + G+D+ F+ ++ ++ V+ +
Sbjct: 11 LTVEEAITIQEELRHQVITEDQFTQP--VQYVAGVDMGFE-ADGTISRAAVAVLSFPDLQ 67
Query: 311 LVRKHEKIVSIIEPYIVNYLAFRECEHMVGTIKEFLVLYPEMKPQVILVDGNGVYHTMGF 490
++ + PYI +L+FRE ++ + + + KP +IL DG G+ H
Sbjct: 68 VIETNLAYRPTSFPYIPGFLSFREIPAVLDALAKV-----QTKPDIILCDGQGIAHPRRL 122
Query: 491 GSACQLGVRLEQEGIDIPTVGVAKNYLQLHGMPSREELKEK--ITDHMIDGSEILLDLFL 664
G A LGV L +IPT+GVAK+ L + EEL + +I EI+
Sbjct: 123 GIASHLGVLL-----NIPTIGVAKSLL----IGKHEELADTKGSWQPLIHRGEII----- 168
Query: 665 DEESNAICTVRRCDKSNLSKDVNKLG-KLAFISAGHRITLKTAVNIVRICS-KCRMPEPI 838
A+ R +G K ++S+GH+I+L TA++ V C+ K R+PE
Sbjct: 169 ----GAVLRTR-------------VGVKPVYVSSGHKISLPTAIDYVLRCTPKYRLPETT 211
Query: 839 LLADHLAKN 865
+AD LA N
Sbjct: 212 RVADKLASN 220
>sp|Q97M37|NFI_CLOAB Endonuclease V (Deoxyinosine 3'endonuclease) (Deoxyribonuclease V)
(DNase V)
Length = 234
Score = 72.0 bits (175), Expect = 2e-12
Identities = 64/219 (29%), Positives = 102/219 (46%), Gaps = 6/219 (2%)
Frame = +2
Query: 212 NLKLIGGIDISF-DKSNNNLACVCFVVIDSCTKKLVRKHEKIVSIIEPYIVNYLAFRECE 388
++KL G+D+++ K C +VID T +++ K I PY+ +LAFRE
Sbjct: 38 DIKLCAGVDLAYWTKGEKQYGVCCIIVIDYNTGEIIEKAYDYGEIEVPYMPGFLAFRELP 97
Query: 389 HMVGTIKEFLVLYPEMKPQVILVDGNGVYHTMGFGSACQLGVRLEQEGIDIPTVGVAKNY 568
++ T+K+ + +P + + DGNG H G A L + PT+GVAK+Y
Sbjct: 98 LVIKTVKKL-----KNEPDIFMFDGNGYLHYNHMGIATHASFFLNK-----PTIGVAKSY 147
Query: 569 LQLHGMPSREELKEKITDHMIDGSEILLDLFLDEESNAICTVRRCDKSNLSKDVNKLGKL 748
L++ G+ E+ E +G+ D+ ++EE KDV K
Sbjct: 148 LKVAGVDF--EMPES-----FEGA--FKDIVINEEVYGRVL-------RTKKDV----KP 187
Query: 749 AFISAGHRITLKTAVNIVRICSK-----CRMPEPILLAD 850
F+S G+ I L+T +ICSK R+P + LAD
Sbjct: 188 IFVSCGNYIDLETC---TKICSKLINNDSRLPITVRLAD 223
>sp|O30108|NFI_ARCFU Endonuclease V (Deoxyinosine 3'endonuclease) (Deoxyribonuclease V)
(DNase V)
Length = 221
Score = 70.1 bits (170), Expect = 9e-12
Identities = 70/253 (27%), Positives = 114/253 (45%), Gaps = 1/253 (0%)
Frame = +2
Query: 137 LDNVESWQEELNHKIDDMNDLIIPSNLKLIGGIDISFDKSNNNLACVCFVVIDSCTKKLV 316
L+ + QEE++ + + DLI L+ + G+D +F C V + ++V
Sbjct: 6 LEELRRIQEEMSRSVV-LEDLIPLEELEYVVGVDQAFISDE---VVSCAVKLTFPELEVV 61
Query: 317 RKHEKIVSIIEPYIVNYLAFRECEHMVGTIKEFLVLYPEMKPQVILVDGNGVYHTMGFGS 496
K ++ + PYI +L FRE E V +K + I+VDG+G+ H G
Sbjct: 62 DKAVRVEKVTFPYIPTFLMFREGEPAVNAVKGLV-----DDRAAIMVDGSGIAHPRRCGL 116
Query: 497 ACQLGVRLEQEGIDIPTVGVAKNYLQLHGMPSREELKEKITDHMIDGSEILLDLFLDEES 676
A + ++L + PTVG+ K L E+++ + ++DGSE +
Sbjct: 117 ATYIALKLRK-----PTVGITKKRL----FGEMVEVEDGLW-RLLDGSETI--------G 158
Query: 677 NAICTVRRCDKSNLSKDVNKLGKLAFISAGHRITLKTAVNIVRICSK-CRMPEPILLADH 853
A+ + RRC K FIS G I+ +A+ + R C K ++PEPI +AD
Sbjct: 159 YALKSCRRC-------------KPIFISPGSYISPDSALELTRKCLKGYKLPEPIRIADK 205
Query: 854 LAKNFLEKRKNAP 892
L K KR+ P
Sbjct: 206 LTKEV--KRELTP 216
>sp|Q8ZYP2|NFI_PYRAE Endonuclease V (Deoxyinosine 3'endonuclease) (Deoxyribonuclease V)
(DNase V)
Length = 215
Score = 69.3 bits (168), Expect = 2e-11
Identities = 66/227 (29%), Positives = 105/227 (46%)
Frame = +2
Query: 215 LKLIGGIDISFDKSNNNLACVCFVVIDSCTKKLVRKHEKIVSIIEPYIVNYLAFRECEHM 394
++ + G+D+++ S LA VV+ T ++V + I+ PY+ +LAFRE M
Sbjct: 28 VETVAGLDVAYSGS---LAFGAAVVVKRTTLEVVETACSVSRIVVPYVPTFLAFRELTPM 84
Query: 395 VGTIKEFLVLYPEMKPQVILVDGNGVYHTMGFGSACQLGVRLEQEGIDIPTVGVAKNYLQ 574
++ ++ L + KP VILVDG+GV H FG A +GV L++ PT+GVAK+ +
Sbjct: 85 ---LRAYIKL--KSKPDVILVDGHGVAHPRRFGIASHIGVVLKK-----PTIGVAKS--R 132
Query: 575 LHGMPSREELKEKITDHMIDGSEILLDLFLDEESNAICTVRRCDKSNLSKDVNKLGKLAF 754
L+G EE+ +K+ D G + L + K G +
Sbjct: 133 LYG----EEVGDKLVD-PATGEVLAL-------------------------IIKCGGKKY 162
Query: 755 ISAGHRITLKTAVNIVRICSKCRMPEPILLADHLAKNFLEKRKNAPE 895
+S G TL A +V K P+ LA LA K+ + P+
Sbjct: 163 VSVGSYATLDEAAGLVAQLCKSGDVYPLRLAHELANKL--KKAHLPD 207
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 108,634,842
Number of Sequences: 369166
Number of extensions: 2329546
Number of successful extensions: 7042
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 6692
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6998
length of database: 68,354,980
effective HSP length: 111
effective length of database: 47,849,395
effective search space used: 10000523555
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)