Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_017_N19
(493 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|O54853|KCNH6_RAT Potassium voltage-gated channel subfami... 36 0.056
sp|O74502|MSH6_SCHPO DNA mismatch repair protein msh6 35 0.073
sp|P23253|TCNA_TRYCR Sialidase (Neuraminidase) (NA) (Major ... 33 0.36
sp|Q9WTW1|GRIP2_RAT Glutamate receptor interacting protein ... 32 0.62
sp|Q9BYJ9|YTHD1_HUMAN YTH domain protein 1 (Dermatomyositis... 32 0.80
sp|Q9VXE5|PAKM_DROME Serine/threonine-protein kinase PAK mb... 32 1.1
sp|Q8FUI4|PKN2_COREF Serine/threonine protein kinases drp72 32 1.1
sp|Q24645|ANTP_DROSU Homeotic antennapedia protein 31 1.8
sp|Q9XGM2|MRE11_ARATH Double-strand break repair protein MRE11 30 2.3
sp|P02833|ANTP_DROME Homeotic antennapedia protein 30 3.1
>sp|O54853|KCNH6_RAT Potassium voltage-gated channel subfamily H member 6 (Voltage-gated
potassium channel subunit Kv11.2) (Ether-a-go-go related
gene potassium channel 2) (Ether-a-go-go related protein
2) (Eag related protein 2)
Length = 950
Score = 35.8 bits (81), Expect = 0.056
Identities = 18/53 (33%), Positives = 29/53 (54%), Gaps = 3/53 (5%)
Frame = +1
Query: 58 PLNYSPGSPHASKSMDNISSMIPAIE---PDKKTRPIGAPPRPISTHGHGAQR 207
P N+SP +PH + +MD +++P+ E P P+ +P RP+ G G R
Sbjct: 871 PRNFSPRTPHVAMAMD--KTLVPSSEQEQPGGLLSPLASPLRPLEVPGLGGSR 921
>sp|O74502|MSH6_SCHPO DNA mismatch repair protein msh6
Length = 1254
Score = 35.4 bits (80), Expect = 0.073
Identities = 31/102 (30%), Positives = 46/102 (45%), Gaps = 7/102 (6%)
Frame = +1
Query: 10 SQEKTP---DNIKNTYK--AAPLNYSPGSP--HASKSMDNISSMIPAIEPDKKTRPIGAP 168
S TP DN N K ++P P SP HA+ +D+ SSM+P D + P+ +
Sbjct: 52 SNHDTPADVDNSSNVNKNSSSPERELPTSPSHHANTEIDSSSSMLPPPSSDPFSSPLSS- 110
Query: 169 PRPISTHGHGAQRPHATSGRHRNPNSHKRNSNSLKPSTIRKI 294
S H +RPH + G +P R S +P + +I
Sbjct: 111 ----SLHRSSPKRPHDSLG-EESPGKLLRTSVKQEPDSEEEI 147
>sp|P23253|TCNA_TRYCR Sialidase (Neuraminidase) (NA) (Major surface antigen)
Length = 1162
Score = 33.1 bits (74), Expect = 0.36
Identities = 23/96 (23%), Positives = 40/96 (41%), Gaps = 2/96 (2%)
Frame = +1
Query: 1 STYSQEKTPDNIKNTYKAAPLNYSPGSPHASKS--MDNISSMIPAIEPDKKTRPIGAPPR 174
S + TP + ++ + P + S H++ S +D+ + P+ D G P
Sbjct: 871 SAHGTPSTP--VDSSAHSTPSTPADSSAHSTPSTPVDSSAHSTPSTPADSSAH--GTPST 926
Query: 175 PISTHGHGAQRPHATSGRHRNPNSHKRNSNSLKPST 282
P+ + HG A S H P++ +S PST
Sbjct: 927 PVDSSAHGTPSTPADSSAHSTPSTPADSSAHSTPST 962
Score = 31.6 bits (70), Expect = 1.1
Identities = 24/95 (25%), Positives = 40/95 (42%), Gaps = 1/95 (1%)
Frame = +1
Query: 1 STYSQEKTP-DNIKNTYKAAPLNYSPGSPHASKSMDNISSMIPAIEPDKKTRPIGAPPRP 177
S + TP D+ ++ + P++ S S S +D+ + P+ D G P P
Sbjct: 655 SAHGTPSTPVDSSAHSTPSTPVDSSAHST-PSTPVDSSAHGAPSTPADSSAH--GTPSTP 711
Query: 178 ISTHGHGAQRPHATSGRHRNPNSHKRNSNSLKPST 282
+ + HG A S H P++ +S PST
Sbjct: 712 VDSSAHGTPSTPADSSAHSTPSTPADSSAHSTPST 746
Score = 30.8 bits (68), Expect = 1.8
Identities = 20/79 (25%), Positives = 33/79 (41%), Gaps = 2/79 (2%)
Frame = +1
Query: 52 AAPLNYSPGSPHASKS--MDNISSMIPAIEPDKKTRPIGAPPRPISTHGHGAQRPHATSG 225
+ P + S H++ S +D+ + P+ D G P P+ + HG A S
Sbjct: 598 STPSTPADSSAHSTPSTPVDSSAHSTPSTPADSSAH--GTPSTPVDSSAHGTPSTPADSS 655
Query: 226 RHRNPNSHKRNSNSLKPST 282
H P++ +S PST
Sbjct: 656 AHGTPSTPVDSSAHSTPST 674
Score = 29.3 bits (64), Expect = 5.2
Identities = 24/96 (25%), Positives = 41/96 (42%), Gaps = 2/96 (2%)
Frame = +1
Query: 1 STYSQEKTP-DNIKNTYKAAPLNYSP-GSPHASKSMDNISSMIPAIEPDKKTRPIGAPPR 174
S + TP D+ ++ + P++ S G+P S +D+ + P+ D G P
Sbjct: 787 SAHGTPSTPVDSSAHSTPSTPVDSSAHGTP--STPVDSSAHSTPSTPVDSSAH--GTPST 842
Query: 175 PISTHGHGAQRPHATSGRHRNPNSHKRNSNSLKPST 282
P+ + H A S H P++ +S PST
Sbjct: 843 PVDSSAHSTPSTPADSSAHSTPSTPADSSAHGTPST 878
Score = 28.9 bits (63), Expect = 6.8
Identities = 22/96 (22%), Positives = 37/96 (38%), Gaps = 2/96 (2%)
Frame = +1
Query: 1 STYSQEKTPDNIKNTYKAAPLNYSPGSPHASKSM--DNISSMIPAIEPDKKTRPIGAPPR 174
S + TP + ++ P + S H++ S D+ + P+ D P
Sbjct: 703 SAHGTPSTP--VDSSAHGTPSTPADSSAHSTPSTPADSSAHSTPSTPADSSAH--STPST 758
Query: 175 PISTHGHGAQRPHATSGRHRNPNSHKRNSNSLKPST 282
P+ + HG A S H P++ +S PST
Sbjct: 759 PVDSSAHGTPSTPADSSAHSTPSTPADSSAHGTPST 794
Score = 28.9 bits (63), Expect = 6.8
Identities = 23/96 (23%), Positives = 38/96 (39%), Gaps = 2/96 (2%)
Frame = +1
Query: 1 STYSQEKTPDNIKNTYKAAPLNYSPGSPHASKS--MDNISSMIPAIEPDKKTRPIGAPPR 174
S +S TP + ++ P + S H++ S +D+ + P+ D G P
Sbjct: 1027 SAHSTPSTPAD--SSAHGTPSTPADSSAHSTPSTPVDSSAHSTPSTPADSSAH--GTPST 1082
Query: 175 PISTHGHGAQRPHATSGRHRNPNSHKRNSNSLKPST 282
P + H A S H P++ +S PST
Sbjct: 1083 PADSSAHSTPSTPADSSAHGTPSTPADSSAHSTPST 1118
Score = 28.5 bits (62), Expect = 8.9
Identities = 23/95 (24%), Positives = 40/95 (42%), Gaps = 1/95 (1%)
Frame = +1
Query: 1 STYSQEKTP-DNIKNTYKAAPLNYSPGSPHASKSMDNISSMIPAIEPDKKTRPIGAPPRP 177
S +S TP D+ ++ + P++ S S ++ + D+ + P+ D G P P
Sbjct: 595 SAHSTPSTPADSSAHSTPSTPVDSSAHSTPSTPA-DSSAHGTPSTPVDSSAH--GTPSTP 651
Query: 178 ISTHGHGAQRPHATSGRHRNPNSHKRNSNSLKPST 282
+ HG S H P++ +S PST
Sbjct: 652 ADSSAHGTPSTPVDSSAHSTPSTPVDSSAHSTPST 686
>sp|Q9WTW1|GRIP2_RAT Glutamate receptor interacting protein 2 (GRIP2 protein) (AMPA
receptor interacting protein GRIP2)
Length = 1043
Score = 32.3 bits (72), Expect = 0.62
Identities = 21/73 (28%), Positives = 30/73 (41%)
Frame = +1
Query: 67 YSPGSPHASKSMDNISSMIPAIEPDKKTRPIGAPPRPISTHGHGAQRPHATSGRHRNPNS 246
++PG S+S+ + P + P P ST G P T+GR R
Sbjct: 380 WAPGGQDQSRSVSSTPFSSPTMNP-------AFPCANASTLPRGPMSPRTTAGRRRQRRK 432
Query: 247 HKRNSNSLKPSTI 285
R+S SL ST+
Sbjct: 433 EHRSSLSLASSTV 445
>sp|Q9BYJ9|YTHD1_HUMAN YTH domain protein 1 (Dermatomyositis associated with cancer
putative autoantigen 1) (DACA-1)
Length = 559
Score = 32.0 bits (71), Expect = 0.80
Identities = 27/127 (21%), Positives = 54/127 (42%)
Frame = +1
Query: 22 TPDNIKNTYKAAPLNYSPGSPHASKSMDNISSMIPAIEPDKKTRPIGAPPRPISTHGHGA 201
T DN K AP+ SP A+ ++ +PA P +P +P T
Sbjct: 273 TWDN-KGPVPKAPVPQQAPSPQAAPQPQQVAQPLPAQPPALAQPQYQSPQQPPQTRWVAP 331
Query: 202 QRPHATSGRHRNPNSHKRNSNSLKPSTIRKIR*NFTLKFILDFYS*YFKMFLTSLKAVKM 381
+ +A G+ S + +++P++ + + L+ + +S K F +LK+ ++
Sbjct: 332 RNRNAAFGQSGGAGSDSNSPGNVQPNSAPSVESHPVLEKLKAAHSYNPKEFEWNLKSGRV 391
Query: 382 FYLFCYT 402
F + Y+
Sbjct: 392 FIIKSYS 398
>sp|Q9VXE5|PAKM_DROME Serine/threonine-protein kinase PAK mbt (p21-activated kinase
related protein) (Mushroom bodies tiny protein)
Length = 639
Score = 31.6 bits (70), Expect = 1.1
Identities = 16/48 (33%), Positives = 23/48 (47%)
Frame = +1
Query: 154 PIGAPPRPISTHGHGAQRPHATSGRHRNPNSHKRNSNSLKPSTIRKIR 297
P+ P+ +HG G P T G SH SNSL+ S+ ++R
Sbjct: 106 PMAPGAHPMMSHGPGMMMPPETGGIVLPKTSHVARSNSLRSSSPPRVR 153
>sp|Q8FUI4|PKN2_COREF Serine/threonine protein kinases drp72
Length = 520
Score = 31.6 bits (70), Expect = 1.1
Identities = 22/89 (24%), Positives = 32/89 (35%)
Frame = +1
Query: 16 EKTPDNIKNTYKAAPLNYSPGSPHASKSMDNISSMIPAIEPDKKTRPIGAPPRPISTHGH 195
++TP + T + +P SP EP ++T P G PP
Sbjct: 411 DETPTRLPTTTQESPTRVSPTPEETD-------------EPGEQTTPGGQPPLSTLPTSL 457
Query: 196 GAQRPHATSGRHRNPNSHKRNSNSLKPST 282
G Q +G NPN+ +N P T
Sbjct: 458 GWQNNQGGTGNQGNPNTTGNPANPGTPGT 486
>sp|Q24645|ANTP_DROSU Homeotic antennapedia protein
Length = 394
Score = 30.8 bits (68), Expect = 1.8
Identities = 21/80 (26%), Positives = 36/80 (45%), Gaps = 3/80 (3%)
Frame = +1
Query: 55 APLNYSP-GSPHASKSMDNISSMIPAIEPDKKTRPIGAPPRPISTHGHGAQRPHA--TSG 225
A L Y+ G P ++ N +M + P+GAPP+ + G G + H G
Sbjct: 220 AQLGYTDVGVPDVTEVHQNHHNMGMYGQQQTGVPPVGAPPQAMMHQGQGPPQMHQGHLPG 279
Query: 226 RHRNPNSHKRNSNSLKPSTI 285
+H P+ + + +S PS +
Sbjct: 280 QHTPPSQNPNSQSSGMPSPL 299
>sp|Q9XGM2|MRE11_ARATH Double-strand break repair protein MRE11
Length = 720
Score = 30.4 bits (67), Expect = 2.3
Identities = 22/82 (26%), Positives = 36/82 (43%), Gaps = 1/82 (1%)
Frame = +1
Query: 52 AAPLNYSPGSPHASKSMDNISSMIPAIEPDKKTRPIGAPPRPISTHGHGAQRPHATS-GR 228
AA + S +D+ SS +EP+ +P + ST G G +RP T GR
Sbjct: 606 AASAAFKSASTIGEDDVDSPSS--EEVEPEDFNKPDSSSEDDESTKGKGRKRPATTKRGR 663
Query: 229 HRNPNSHKRNSNSLKPSTIRKI 294
R + KR + S++ ++
Sbjct: 664 GRGSGTSKRGRKNESSSSLNRL 685
>sp|P02833|ANTP_DROME Homeotic antennapedia protein
Length = 378
Score = 30.0 bits (66), Expect = 3.1
Identities = 14/45 (31%), Positives = 24/45 (53%), Gaps = 1/45 (2%)
Frame = +1
Query: 154 PIGAPPRPISTHGHGAQRPH-ATSGRHRNPNSHKRNSNSLKPSTI 285
P+GAPP+ + G G + H G+H P+ + + +S PS +
Sbjct: 239 PVGAPPQGMMHQGQGPPQMHQGHPGQHTPPSQNPNSQSSGMPSPL 283
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 54,362,104
Number of Sequences: 369166
Number of extensions: 1046448
Number of successful extensions: 3371
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3182
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3341
length of database: 68,354,980
effective HSP length: 102
effective length of database: 49,512,010
effective search space used: 3020232610
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)