Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_017_N14
(905 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P23561|STE11_YEAST Serine/threonine-protein kinase STE11 46 2e-04
sp|Q99683|M3K5_HUMAN Mitogen-activated protein kinase kinas... 45 3e-04
sp|P06243|CDC7_YEAST Cell division control protein 7 45 3e-04
sp|O22040|M3K1_ARATH Mitogen-activated protein kinase kinas... 45 3e-04
sp|P34556|CDC2_CAEEL Cell division control protein 2 homolo... 43 0.001
sp|O22042|M3K3_ARATH Mitogen-activated protein kinase kinas... 43 0.001
sp|Q91727|CDK4_XENLA Cell division protein kinase 4 (Cyclin... 42 0.002
sp|P41892|CDC7_SCHPO Cell division control protein 7 42 0.003
sp|Q61084|M3K3_MOUSE Mitogen-activated protein kinase kinas... 42 0.003
sp|P35426|CDK4_RAT Cell division protein kinase 4 (Cyclin-d... 42 0.003
>sp|P23561|STE11_YEAST Serine/threonine-protein kinase STE11
Length = 738
Score = 45.8 bits (107), Expect = 2e-04
Identities = 24/50 (48%), Positives = 30/50 (60%)
Frame = +3
Query: 723 GSISEKISLNNYQPLPVKTIKLYTKQILSGLKFLHQSRIIHRDIKSIYFL 872
GS+S LNNY P I +T+QIL G+ +LH+ IIHRDIK L
Sbjct: 560 GSVSSM--LNNYGPFEESLITNFTRQILIGVAYLHKKNIIHRDIKGANIL 607
>sp|Q99683|M3K5_HUMAN Mitogen-activated protein kinase kinase kinase 5 (MAPK/ERK kinase
kinase 5) (MEK kinase 5) (MEKK 5) (Apoptosis
signal-regulating kinase 1) (ASK-1)
Length = 1374
Score = 45.1 bits (105), Expect = 3e-04
Identities = 19/28 (67%), Positives = 24/28 (85%)
Frame = +3
Query: 774 KTIKLYTKQILSGLKFLHQSRIIHRDIK 857
+TI YTKQIL GLK+LH ++I+HRDIK
Sbjct: 778 QTIGFYTKQILEGLKYLHDNQIVHRDIK 805
>sp|P06243|CDC7_YEAST Cell division control protein 7
Length = 507
Score = 45.1 bits (105), Expect = 3e-04
Identities = 21/39 (53%), Positives = 26/39 (66%)
Frame = +3
Query: 756 YQPLPVKTIKLYTKQILSGLKFLHQSRIIHRDIKSIYFL 872
Y+ LP+K IK Y ++L LKF+H IIHRDIK FL
Sbjct: 132 YRDLPIKGIKKYIWELLRALKFVHSKGIIHRDIKPTNFL 170
>sp|O22040|M3K1_ARATH Mitogen-activated protein kinase kinase kinase 1 (Arabidospsis
NPK1-related protein kinase 1)
Length = 666
Score = 45.1 bits (105), Expect = 3e-04
Identities = 22/50 (44%), Positives = 30/50 (60%)
Frame = +3
Query: 723 GSISEKISLNNYQPLPVKTIKLYTKQILSGLKFLHQSRIIHRDIKSIYFL 872
GSIS L + P P ++ YT+Q+L GL++LH I+HRDIK L
Sbjct: 157 GSISSL--LEKFGPFPESVVRTYTRQLLLGLEYLHNHAIMHRDIKGANIL 204
>sp|P34556|CDC2_CAEEL Cell division control protein 2 homolog (p34 protein kinase)
Length = 332
Score = 42.7 bits (99), Expect = 0.001
Identities = 18/31 (58%), Positives = 24/31 (77%)
Frame = +3
Query: 765 LPVKTIKLYTKQILSGLKFLHQSRIIHRDIK 857
LP++T+K YT QIL + F HQ R+IHRD+K
Sbjct: 118 LPLETLKSYTFQILQAMCFCHQRRVIHRDLK 148
>sp|O22042|M3K3_ARATH Mitogen-activated protein kinase kinase kinase 3 (Arabidospsis
NPK1-related protein kinase 3)
Length = 651
Score = 42.7 bits (99), Expect = 0.001
Identities = 23/50 (46%), Positives = 30/50 (60%)
Frame = +3
Query: 723 GSISEKISLNNYQPLPVKTIKLYTKQILSGLKFLHQSRIIHRDIKSIYFL 872
GSIS L + P I +YTKQ+L GL++LH + I+HRDIK L
Sbjct: 156 GSISSL--LEKFGSFPEPVIIMYTKQLLLGLEYLHNNGIMHRDIKGANIL 203
>sp|Q91727|CDK4_XENLA Cell division protein kinase 4 (Cyclin-dependent kinase 4)
Length = 319
Score = 42.0 bits (97), Expect = 0.002
Identities = 19/31 (61%), Positives = 25/31 (80%)
Frame = +3
Query: 765 LPVKTIKLYTKQILSGLKFLHQSRIIHRDIK 857
LP++TIK KQ LSGL+FLH + I+HRD+K
Sbjct: 112 LPLETIKDLMKQFLSGLEFLHLNCIVHRDLK 142
>sp|P41892|CDC7_SCHPO Cell division control protein 7
Length = 1062
Score = 41.6 bits (96), Expect = 0.003
Identities = 18/40 (45%), Positives = 24/40 (60%)
Frame = +3
Query: 753 NYQPLPVKTIKLYTKQILSGLKFLHQSRIIHRDIKSIYFL 872
N+ +P + LYT Q+L GL +LH +IHRDIK L
Sbjct: 99 NFGKIPENLVALYTFQVLQGLLYLHNQGVIHRDIKGANIL 138
>sp|Q61084|M3K3_MOUSE Mitogen-activated protein kinase kinase kinase 3 (MAPK/ERK kinase
kinase 3) (MEK kinase 3) (MEKK 3)
Length = 626
Score = 41.6 bits (96), Expect = 0.003
Identities = 20/47 (42%), Positives = 26/47 (55%)
Frame = +3
Query: 732 SEKISLNNYQPLPVKTIKLYTKQILSGLKFLHQSRIIHRDIKSIYFL 872
S K L Y L + YT+QIL G+ +LH + I+HRDIK L
Sbjct: 450 SVKDQLKAYGALTESVTRKYTRQILEGMSYLHSNMIVHRDIKGANIL 496
>sp|P35426|CDK4_RAT Cell division protein kinase 4 (Cyclin-dependent kinase 4) (PSK-J3)
Length = 303
Score = 41.6 bits (96), Expect = 0.003
Identities = 19/31 (61%), Positives = 24/31 (77%)
Frame = +3
Query: 765 LPVKTIKLYTKQILSGLKFLHQSRIIHRDIK 857
LPV+TIK +Q LSGL FLH + I+HRD+K
Sbjct: 112 LPVETIKDLMRQFLSGLDFLHANCIVHRDLK 142
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 84,707,529
Number of Sequences: 369166
Number of extensions: 1424054
Number of successful extensions: 4274
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4170
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4273
length of database: 68,354,980
effective HSP length: 110
effective length of database: 48,034,130
effective search space used: 9174518830
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)