Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_017_M24
(801 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P42932|TCPQ_MOUSE T-complex protein 1, theta subunit (TC... 288 1e-77
sp|P50990|TCPQ_HUMAN T-complex protein 1, theta subunit (TC... 286 6e-77
sp|P47079|TCPQ_YEAST T-complex protein 1, theta subunit (TC... 216 8e-56
sp|P78921|TCPQ_SCHPO Probable T-complex protein 1, theta su... 216 8e-56
sp|P47828|TCPQ_CANAL T-complex protein 1, theta subunit (TC... 187 3e-47
sp|Q58405|THS_METJA Thermosome subunit (Chaperonin subunit) 145 2e-34
sp|Q9V2Q7|THS_PYRAB Thermosome subunit (Chaperonin subunit) 134 2e-31
sp|O57762|THS_PYRHO Thermosome subunit (Chaperonin subunit) 134 2e-31
sp|O26885|THSB_METTH Thermosome beta subunit (Thermosome su... 134 3e-31
sp|O93624|THS_METTL Thermosome subunit (Chaperonin subunit) 134 3e-31
>sp|P42932|TCPQ_MOUSE T-complex protein 1, theta subunit (TCP-1-theta) (CCT-theta)
Length = 548
Score = 288 bits (737), Expect = 1e-77
Identities = 142/263 (53%), Positives = 196/263 (74%)
Frame = +2
Query: 11 TETKGTVLINTAKELMDFSRGEEDQMEERVREIAETGCKVIVTGGKVGELALHYANKYNL 190
TETKGTVLI TA+ELM+FS+GEE+ M+ +V+ IA TG VIVTGGKV ++ALHYANKYN+
Sbjct: 251 TETKGTVLIKTAEELMNFSKGEENLMDAQVKAIAGTGANVIVTGGKVADIALHYANKYNI 310
Query: 191 MVVKLSSKFDIRRVCKVTGATPIPKLSTPTQEELGYIASVRTEEIGKSTVVLFDQDVKEG 370
M+V+L+SK+D+RR+CK GAT +PKL+ P QEE+G+ SV E+G + VV+F + ++G
Sbjct: 311 MLVRLNSKWDLRRLCKTVGATALPKLTPPVQEEMGHCDSVYLSEVGDTQVVVFKHEKEDG 370
Query: 371 AISSIVVRGSMYDMMDEVERAIDDGVNTFKCLTKEPRYLAGAGATEIELANRLSDFANTQ 550
AIS+IV+RGS ++MD++ERA+DDGVNTFK LT++ R + G GATEIELA +++ + T
Sbjct: 371 AISTIVLRGSTDNLMDDIERAVDDGVNTFKVLTRDKRLVPGGGATEIELAKQITSYGETC 430
Query: 551 TGLVQYAIKQFVLAFESIVKVLCDNAGENATERIAELKAHHREGKTTFGIISTSEGRKVD 730
GL QYAIK+F AFE+I + L +N+G A E I++L + H+EG G+ +E V
Sbjct: 431 PGLEQYAIKKFAEAFEAIPRALAENSGVKANEVISKLYSVHQEGNKNVGLDIEAEVPAVK 490
Query: 731 DAVEHQILDTYTAKYWGIRFAAD 799
D +E ILDTY KYW I+ A +
Sbjct: 491 DMLEASILDTYLGKYWAIKLATN 513
>sp|P50990|TCPQ_HUMAN T-complex protein 1, theta subunit (TCP-1-theta) (CCT-theta)
sp|Q5RAP1|TCPQ_PONPY T-complex protein 1, theta subunit (TCP-1-theta) (CCT-theta)
Length = 548
Score = 286 bits (731), Expect = 6e-77
Identities = 140/263 (53%), Positives = 196/263 (74%)
Frame = +2
Query: 11 TETKGTVLINTAKELMDFSRGEEDQMEERVREIAETGCKVIVTGGKVGELALHYANKYNL 190
TETKGTVLI TA+ELM+FS+GEE+ M+ +V+ IA+TG V+VTGGKV ++ALHYANKYN+
Sbjct: 251 TETKGTVLIKTAEELMNFSKGEENLMDAQVKAIADTGANVVVTGGKVADMALHYANKYNI 310
Query: 191 MVVKLSSKFDIRRVCKVTGATPIPKLSTPTQEELGYIASVRTEEIGKSTVVLFDQDVKEG 370
M+V+L+SK+D+RR+CK GAT +P+L+ P EE+G+ SV E+G + VV+F + ++G
Sbjct: 311 MLVRLNSKWDLRRLCKTVGATALPRLTPPVLEEMGHCDSVYLSEVGDTQVVVFKHEKEDG 370
Query: 371 AISSIVVRGSMYDMMDEVERAIDDGVNTFKCLTKEPRYLAGAGATEIELANRLSDFANTQ 550
AIS+IV+RGS ++MD++ERA+DDGVNTFK LT++ R + G GATEIELA +++ + T
Sbjct: 371 AISTIVLRGSTDNLMDDIERAVDDGVNTFKVLTRDKRLVPGGGATEIELAKQITSYGETC 430
Query: 551 TGLVQYAIKQFVLAFESIVKVLCDNAGENATERIAELKAHHREGKTTFGIISTSEGRKVD 730
GL QYAIK+F AFE+I + L +N+G A E I++L A H+EG G+ +E V
Sbjct: 431 PGLEQYAIKKFAEAFEAIPRALAENSGVKANEVISKLYAVHQEGNKNVGLDIEAEVPAVK 490
Query: 731 DAVEHQILDTYTAKYWGIRFAAD 799
D +E ILDTY KYW I+ A +
Sbjct: 491 DMLEAGILDTYLGKYWAIKLATN 513
>sp|P47079|TCPQ_YEAST T-complex protein 1, theta subunit (TCP-1-theta) (CCT-theta)
Length = 568
Score = 216 bits (549), Expect = 8e-56
Identities = 121/277 (43%), Positives = 172/277 (62%), Gaps = 14/277 (5%)
Frame = +2
Query: 11 TETKGTVLINTAKELMDFSRGEEDQMEERVREIAETGCKVIVTGGKVGELALHYANKYNL 190
TETKGTVL++ A+E++DFS+GEE Q++ ++EIA+ G + IV G VGELALHY N+Y +
Sbjct: 259 TETKGTVLLHNAQEMLDFSKGEEKQIDAMMKEIADMGVECIVAGAGVGELALHYLNRYGI 318
Query: 191 MVVKLSSKFDIRRVCKVTGATPIPKLSTPTQEELGYIASVRTEEIGKSTVVLFDQDVKE- 367
+V+K+ SKF++RR+C+V GATP+P+L PT EELG + +V+T EIG V +F Q+ E
Sbjct: 319 LVLKVPSKFELRRLCRVCGATPLPRLGAPTPEELGLVETVKTMEIGGDRVTVFKQEQGEI 378
Query: 368 GAISSIVVRGSMYDMMDEVERAIDDGVNTFKCLTKEP--RYLAGAGATEIELANRLSDFA 541
S+I++RG+ + +D++ERAIDDGV K L K + L GAGATEIEL +R++ +
Sbjct: 379 SRTSTIILRGATQNNLDDIERAIDDGVAAVKGLMKPSGGKLLPGAGATEIELISRITKYG 438
Query: 542 NTQTGLVQYAIKQFVLAFESIVKVLCDNAGENATERIAELKAHHREGKTTFGIISTSEGR 721
GL+Q AIKQF +AFE + + L + AG + E + L A H T G + T
Sbjct: 439 ERTPGLLQLAIKQFAVAFEVVPRTLAETAGLDVNEVLPNLYAAH--NVTEPGAVKTDHLY 496
Query: 722 K-----------VDDAVEHQILDTYTAKYWGIRFAAD 799
K V D E I D K + I A +
Sbjct: 497 KGVDIDGESDEGVKDIREENIYDMLATKKFAINVATE 533
>sp|P78921|TCPQ_SCHPO Probable T-complex protein 1, theta subunit (TCP-1-theta) (CCT-theta)
Length = 546
Score = 216 bits (549), Expect = 8e-56
Identities = 111/265 (41%), Positives = 170/265 (64%), Gaps = 1/265 (0%)
Frame = +2
Query: 8 QTETKGTVLINTAKELMDFSRGEEDQMEERVREIAETGCKVIVTGGKVGELALHYANKYN 187
QTETKGTVL++ A+E++DFS+GEE+ +E ++EI + G +V+VT G V +L LHY N++
Sbjct: 250 QTETKGTVLLHNAQEMLDFSKGEENLIESHIKEIYDAGVRVVVTSGNVNDLVLHYLNRFE 309
Query: 188 LMVVKLSSKFDIRRVCKVTGATPIPKLSTPTQEELGYIASVRTEEIGKSTVVLFDQDVKE 367
++V+++ SKF++RR+C+V GATP+ ++ P EE+G + V T EIG V +F Q
Sbjct: 310 ILVIRVPSKFELRRLCRVVGATPLARMGVPMPEEMGSVDVVETIEIGGDRVTVFRQVEDI 369
Query: 368 GAISSIVVRGSMYDMMDEVERAIDDGVNTFKCLTKEPRYLAGAGATEIELANRLSDFANT 547
++IV+RG+ +D++ERAIDDGVN K L K+ R + GAGA++++L RL
Sbjct: 370 TRTATIVLRGATKTYLDDLERAIDDGVNIVKALVKDNRLIFGAGASDMQLCIRLISVGEK 429
Query: 548 QTGLVQYAIKQFVLAFESIVKVLCDNAGENATERIAEL-KAHHREGKTTFGIISTSEGRK 724
G+ Q+AIKQ+ AFE + + + +NAG + T+ I++L AHH+E + G+ E
Sbjct: 430 TPGIYQHAIKQYGEAFEVVPRTISENAGLDPTDVISKLYAAHHKENGESIGVDVECENDG 489
Query: 725 VDDAVEHQILDTYTAKYWGIRFAAD 799
DA E I D AK IR A +
Sbjct: 490 TLDAKEAGIFDVLLAKKSAIRLATE 514
>sp|P47828|TCPQ_CANAL T-complex protein 1, theta subunit (TCP-1-theta) (CCT-theta)
Length = 540
Score = 187 bits (475), Expect = 3e-47
Identities = 103/244 (42%), Positives = 147/244 (60%)
Frame = +2
Query: 68 RGEEDQMEERVREIAETGCKVIVTGGKVGELALHYANKYNLMVVKLSSKFDIRRVCKVTG 247
R + + R+ G + ++ G VGELALHY NKY ++V+++ SKFD+RR+C+V G
Sbjct: 267 RAKNNSWTSCARKSTIQGLRWLLPGSSVGELALHYLNKYGILVLRVPSKFDLRRICQVCG 326
Query: 248 ATPIPKLSTPTQEELGYIASVRTEEIGKSTVVLFDQDVKEGAISSIVVRGSMYDMMDEVE 427
ATP+P+L PT +E+G I + T+EIG V +F QD ++IVVRG+ + +D++E
Sbjct: 327 ATPLPRLGAPTPDEMGEIDIIETKEIGGDRVTIFRQDESSSRTATIVVRGATQNNLDDIE 386
Query: 428 RAIDDGVNTFKCLTKEPRYLAGAGATEIELANRLSDFANTQTGLVQYAIKQFVLAFESIV 607
RAIDDGVN+ K L K+ R L GAGA EIEL R++ + +T GL+Q AIK F AFE I
Sbjct: 387 RAIDDGVNSIKGLIKDNRLLPGAGAVEIELMKRITAYQST-PGLLQLAIKSFAKAFEVIP 445
Query: 608 KVLCDNAGENATERIAELKAHHREGKTTFGIISTSEGRKVDDAVEHQILDTYTAKYWGIR 787
+VL + +G +++E +++L A H E I G D AV LD K I
Sbjct: 446 RVLAETSGHDSSEILSKLHAAHAEDTGLRAGIDIDSGEVADTAV----LDILATKKSAID 501
Query: 788 FAAD 799
A D
Sbjct: 502 LAVD 505
>sp|Q58405|THS_METJA Thermosome subunit (Chaperonin subunit)
Length = 542
Score = 145 bits (365), Expect = 2e-34
Identities = 84/242 (34%), Positives = 132/242 (54%), Gaps = 1/242 (0%)
Frame = +2
Query: 8 QTETKGTVLINTAKELMDFSRGEEDQMEERVREIAETGCKVIVTGGKVGELALHYANKYN 187
+TET + I +LM+F EE +++ V +IA TG V+ + +LA HY K
Sbjct: 247 ETETDAEIRITDPAKLMEFIEQEEKMIKDMVEKIAATGANVVFCQKGIDDLAQHYLAKKG 306
Query: 188 LMVVKLSSKFDIRRVCKVTGATPIPKLSTPTQEELGYIASVRTEEIGKSTVVLFDQDVKE 367
++ V+ K D+ ++ K TGA + K+ T E+LG V ++ ++ +Q
Sbjct: 307 ILAVRRVKKSDMEKLAKATGARIVTKIDDLTPEDLGEAGLVEERKVAGDAMIFVEQCKHP 366
Query: 368 GAISSIVVRGSMYDMMDEVERAIDDGVNTFKCLTKEPRYLAGAGATEIELANRLSDFANT 547
A++ I+ RGS +++EV RAIDD + KC +E + +AG GATEIELA RL FA +
Sbjct: 367 KAVT-ILARGSTEHVVEEVARAIDDAIGVVKCALEEGKIVAGGGATEIELAKRLRKFAES 425
Query: 548 QTGLVQYAIKQFVLAFESIVKVLCDNAGENATERIAELK-AHHREGKTTFGIISTSEGRK 724
G Q A+K F A E I + L +N+G + + + +L+ AH +EG +G + EG
Sbjct: 426 VAGREQLAVKAFADALEVIPRTLAENSGLDPIDMLVKLRAAHEKEGGEVYG-LDVFEGEV 484
Query: 725 VD 730
VD
Sbjct: 485 VD 486
>sp|Q9V2Q7|THS_PYRAB Thermosome subunit (Chaperonin subunit)
Length = 550
Score = 134 bits (338), Expect = 2e-31
Identities = 81/264 (30%), Positives = 138/264 (52%)
Frame = +2
Query: 8 QTETKGTVLINTAKELMDFSRGEEDQMEERVREIAETGCKVIVTGGKVGELALHYANKYN 187
+TET + I + ++L F EE ++E V +I E G V+ + +LA HY KY
Sbjct: 250 ETETDAEIRITSPEQLQAFLEQEEKMLKEMVDKIKEVGANVVFVQKGIDDLAQHYLAKYG 309
Query: 188 LMVVKLSSKFDIRRVCKVTGATPIPKLSTPTQEELGYIASVRTEEIGKSTVVLFDQDVKE 367
++ V+ K D+ ++ K TGA + + T E+LG V ++ ++ F + K
Sbjct: 310 ILAVRRVKKSDMEKLAKATGAKIVTNIRDLTPEDLGEAELVEERKVAGENMI-FVEGCKN 368
Query: 368 GAISSIVVRGSMYDMMDEVERAIDDGVNTFKCLTKEPRYLAGAGATEIELANRLSDFANT 547
+I++RG ++DEVERA++D V K + ++ + +AG GA EIEL+ +L ++A
Sbjct: 369 PKAVTILIRGGTEHVVDEVERALEDAVKVVKDILEDGKIIAGGGAAEIELSIKLDEYAKE 428
Query: 548 QTGLVQYAIKQFVLAFESIVKVLCDNAGENATERIAELKAHHREGKTTFGIISTSEGRKV 727
G Q AI+ F A + I + L +NAG + E + ++ A H+E T G I EG
Sbjct: 429 VGGKEQLAIEAFAEALKVIPRTLAENAGLDPIETLVKVIAAHKEKGPTIG-IDVYEGEPA 487
Query: 728 DDAVEHQILDTYTAKYWGIRFAAD 799
D +E +++ K I+ A++
Sbjct: 488 -DMMERGVIEPVRVKKQAIKSASE 510
>sp|O57762|THS_PYRHO Thermosome subunit (Chaperonin subunit)
Length = 549
Score = 134 bits (338), Expect = 2e-31
Identities = 80/264 (30%), Positives = 139/264 (52%)
Frame = +2
Query: 8 QTETKGTVLINTAKELMDFSRGEEDQMEERVREIAETGCKVIVTGGKVGELALHYANKYN 187
+TET + I + ++L F EE ++E V +I E G V+ + +LA HY KY
Sbjct: 250 ETETDAEIRITSPEQLQAFLEQEEKMLKEMVDKIKEVGANVVFVQKGIDDLAQHYLAKYG 309
Query: 188 LMVVKLSSKFDIRRVCKVTGATPIPKLSTPTQEELGYIASVRTEEIGKSTVVLFDQDVKE 367
++ V+ K D+ ++ K TGA + + T E+LG V ++ ++ F + K
Sbjct: 310 ILAVRRVKKSDMEKLAKATGAKIVTNIRDLTPEDLGEAELVEERKVAGENMI-FVEGCKN 368
Query: 368 GAISSIVVRGSMYDMMDEVERAIDDGVNTFKCLTKEPRYLAGAGATEIELANRLSDFANT 547
+I++RG ++DEVERA++D + K + ++ + +AG GA+EIEL+ +L ++A
Sbjct: 369 PKAVTILIRGGTEHVVDEVERALEDAIKVVKDILEDGKIIAGGGASEIELSIKLDEYAKE 428
Query: 548 QTGLVQYAIKQFVLAFESIVKVLCDNAGENATERIAELKAHHREGKTTFGIISTSEGRKV 727
G Q AI+ F A + I + L +NAG + E + ++ A H+E T G I EG
Sbjct: 429 VGGKEQLAIEAFAEALKVIPRTLAENAGLDPIETLVKVIAAHKEKGQTIG-IDVYEGEPA 487
Query: 728 DDAVEHQILDTYTAKYWGIRFAAD 799
D +E +++ K I+ A++
Sbjct: 488 -DMMERGVIEPVRVKKQAIKSASE 510
>sp|O26885|THSB_METTH Thermosome beta subunit (Thermosome subunit 2) (Chaperonin beta
subunit)
Length = 538
Score = 134 bits (337), Expect = 3e-31
Identities = 80/264 (30%), Positives = 140/264 (53%)
Frame = +2
Query: 8 QTETKGTVLINTAKELMDFSRGEEDQMEERVREIAETGCKVIVTGGKVGELALHYANKYN 187
+TE + I ++ F EE + + V I +TG V+ + +LA HY K
Sbjct: 243 ETEVDAEIRITDPSQMQAFIEQEEQMIRDMVNSIVDTGANVLFCQKGIDDLAQHYLAKAG 302
Query: 188 LMVVKLSSKFDIRRVCKVTGATPIPKLSTPTQEELGYIASVRTEEIGKSTVVLFDQDVKE 367
++ V+ K D+ ++ K TGA + + + E+LG V ++I ++ F ++ KE
Sbjct: 303 VLAVRRVKKSDMEKLSKATGANIVTNIEDLSPEDLGEAGVVSEKKISGEEMI-FVEECKE 361
Query: 368 GAISSIVVRGSMYDMMDEVERAIDDGVNTFKCLTKEPRYLAGAGATEIELANRLSDFANT 547
+I+VRGS ++ EVERAI+D + ++ + +AG GA EIE+A RL D+A++
Sbjct: 362 PKAVTILVRGSTEHVVSEVERAIEDAIGVVAATVEDGKVVAGGGAPEIEIAKRLKDYADS 421
Query: 548 QTGLVQYAIKQFVLAFESIVKVLCDNAGENATERIAELKAHHREGKTTFGIISTSEGRKV 727
+G Q A+ F A E + K L +NAG ++ + + +L+A H E +T+ I +G K+
Sbjct: 422 ISGREQLAVSAFAEALEIVPKTLAENAGLDSIDVLVDLRAAHEE--STYMGIDVFDG-KI 478
Query: 728 DDAVEHQILDTYTAKYWGIRFAAD 799
D E +++ + K I+ AA+
Sbjct: 479 VDMKEAGVIEPHRVKKQAIQSAAE 502
>sp|O93624|THS_METTL Thermosome subunit (Chaperonin subunit)
Length = 544
Score = 134 bits (337), Expect = 3e-31
Identities = 76/264 (28%), Positives = 138/264 (52%)
Frame = +2
Query: 8 QTETKGTVLINTAKELMDFSRGEEDQMEERVREIAETGCKVIVTGGKVGELALHYANKYN 187
+TET + I +LM+F EE +++ V I +G V+ + +LA HY K
Sbjct: 245 ETETDAEIRITDPTKLMEFIEQEEKMLKDMVDTIKASGANVLFCQKGIDDLAQHYLAKEG 304
Query: 188 LMVVKLSSKFDIRRVCKVTGATPIPKLSTPTQEELGYIASVRTEEIGKSTVVLFDQDVKE 367
++ V+ K D+ ++ K TGA + + E+LG V +I ++ F ++ K
Sbjct: 305 ILAVRRVKKSDMEKLSKATGANVVTNIKDLKAEDLGEAGIVEERKIAGDAMI-FVEECKH 363
Query: 368 GAISSIVVRGSMYDMMDEVERAIDDGVNTFKCLTKEPRYLAGAGATEIELANRLSDFANT 547
++++RG+ +++EV RA+DD + C ++ + +AG GA EIELA +L D+A
Sbjct: 364 PKAVTMLIRGTTEHVIEEVARAVDDAIGVVACTIEDGKIVAGGGAAEIELAMKLRDYAEG 423
Query: 548 QTGLVQYAIKQFVLAFESIVKVLCDNAGENATERIAELKAHHREGKTTFGIISTSEGRKV 727
+G Q A++ F A E + + L +NAG +A E + +L+A H EG + ++ G V
Sbjct: 424 VSGREQLAVRAFADALEVVPRTLAENAGLDAIEMLVKLRAKHAEGNNAYYGLNVFTG-DV 482
Query: 728 DDAVEHQILDTYTAKYWGIRFAAD 799
++ E+ +++ K I+ A +
Sbjct: 483 ENMTENGVVEPLRVKTQAIQSATE 506
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 86,527,613
Number of Sequences: 369166
Number of extensions: 1661180
Number of successful extensions: 5291
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4961
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5218
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 7570361805
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)