Planarian EST Database


Dr_sW_017_L19

BLASTX 2.2.12 [Aug-07-2005]

Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= Dr_sW_017_L19
         (809 letters)

Database: Non-redundant SwissProt sequences 
           184,735 sequences; 68,354,980 total letters



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

sp|P07688|CATB_BOVIN  Cathepsin B precursor [Contains: Cathe...   297   3e-80
sp|P00787|CATB_RAT  Cathepsin B precursor (Cathepsin B1) (RS...   294   2e-79
sp|P10605|CATB_MOUSE  Cathepsin B precursor (Cathepsin B1) [...   292   6e-79
sp|P07858|CATB_HUMAN  Cathepsin B precursor (Cathepsin B1) (...   284   2e-76
sp|P43233|CATB_CHICK  Cathepsin B precursor (Cathepsin B1) [...   276   5e-74
sp|P43157|CYSP_SCHJA  Cathepsin B-like cysteine proteinase p...   268   1e-71
sp|P25792|CYSP_SCHMA  Cathepsin B-like cysteine proteinase p...   250   3e-66
sp|P43510|CPR6_CAEEL  Cathepsin B-like cysteine proteinase 6...   224   3e-58
sp|P43509|CPR5_CAEEL  Cathepsin B-like cysteine proteinase 5...   205   1e-52
sp|P25807|CPR1_CAEEL  Gut-specific cysteine proteinase precu...   203   4e-52
>sp|P07688|CATB_BOVIN Cathepsin B precursor [Contains: Cathepsin B light chain; Cathepsin
           B heavy chain]
          Length = 335

 Score =  297 bits (760), Expect = 3e-80
 Identities = 141/242 (58%), Positives = 171/242 (70%), Gaps = 1/242 (0%)
 Frame = +2

Query: 86  PLSFDLINYVNYIAQTTWKAGPTTRFQSISDIRKVLG-VMKDPNNFKLPKRKPLLNRVRL 262
           PLS +L+N+VN    TTWKAG       +S ++K+ G ++  P   KLP+R      V L
Sbjct: 25  PLSDELVNFVNK-QNTTWKAGHNFYNVDLSYVKKLCGAILGGP---KLPQRDAFAADVVL 80

Query: 263 PTTFDARVQWPKCKSIGEIRDQSNCGSCWAFGAVEAITDRYCIHSNGTQTPRISAEDLLT 442
           P +FDAR QWP C +I EIRDQ +CGSCWAFGAVEAI+DR CIHSNG     +SAED+LT
Sbjct: 81  PESFDAREQWPNCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHSNGRVNVEVSAEDMLT 140

Query: 443 CCGFRCGDGCNGGFPSGAWHYWVTDGLVTGGEYGAHLGCQDYAFPKCSHHVIGPYPNCTG 622
           CCG  CGDGCNGGFPSGAW++W   GLV+GG Y +H+GC+ Y+ P C HHV G  P CTG
Sbjct: 141 CCGGECGDGCNGGFPSGAWNFWTKKGLVSGGLYNSHVGCRPYSIPPCEHHVNGSRPPCTG 200

Query: 623 EFPTPKCKKACQAGYSKTYAEDKQYGKSSYSVDSNQQAIMQEILTNGPVEAAFSVYADFP 802
           E  TPKC K C+ GYS +Y EDK +G SSYSV +N++ IM EI  NGPVE AFSVY+DF 
Sbjct: 201 EGDTPKCNKTCEPGYSPSYKEDKHFGCSSYSVANNEKEIMAEIYKNGPVEGAFSVYSDFL 260

Query: 803 SY 808
            Y
Sbjct: 261 LY 262
>sp|P00787|CATB_RAT Cathepsin B precursor (Cathepsin B1) (RSG-2) [Contains: Cathepsin B
           light chain; Cathepsin B heavy chain]
          Length = 339

 Score =  294 bits (752), Expect = 2e-79
 Identities = 137/246 (55%), Positives = 171/246 (69%), Gaps = 1/246 (0%)
 Frame = +2

Query: 74  PIHTPLSFDLINYVNYIAQTTWKAGPTTRFQSISDIRKVLG-VMKDPNNFKLPKRKPLLN 250
           P   PLS D+INY+N    TTW+AG       IS ++K+ G V+  PN   LP+R     
Sbjct: 21  PSSHPLSDDMINYINK-QNTTWQAGRNFYNVDISYLKKLCGTVLGGPN---LPERVGFSE 76

Query: 251 RVRLPTTFDARVQWPKCKSIGEIRDQSNCGSCWAFGAVEAITDRYCIHSNGTQTPRISAE 430
            + LP +FDAR QW  C +I +IRDQ +CGSCWAFGAVEA++DR CIH+NG     +SAE
Sbjct: 77  DINLPESFDAREQWSNCPTIAQIRDQGSCGSCWAFGAVEAMSDRICIHTNGRVNVEVSAE 136

Query: 431 DLLTCCGFRCGDGCNGGFPSGAWHYWVTDGLVTGGEYGAHLGCQDYAFPKCSHHVIGPYP 610
           DLLTCCG +CGDGCNGG+PSGAW++W   GLV+GG Y +H+GC  Y  P C HHV G  P
Sbjct: 137 DLLTCCGIQCGDGCNGGYPSGAWNFWTRKGLVSGGVYNSHIGCLPYTIPPCEHHVNGSRP 196

Query: 611 NCTGEFPTPKCKKACQAGYSKTYAEDKQYGKSSYSVDSNQQAIMQEILTNGPVEAAFSVY 790
            CTGE  TPKC K C+AGYS +Y EDK YG +SYSV  +++ IM EI  NGPVE AF+V+
Sbjct: 197 PCTGEGDTPKCNKMCEAGYSTSYKEDKHYGYTSYSVSDSEKEIMAEIYKNGPVEGAFTVF 256

Query: 791 ADFPSY 808
           +DF +Y
Sbjct: 257 SDFLTY 262
>sp|P10605|CATB_MOUSE Cathepsin B precursor (Cathepsin B1) [Contains: Cathepsin B light
           chain; Cathepsin B heavy chain]
          Length = 339

 Score =  292 bits (748), Expect = 6e-79
 Identities = 139/246 (56%), Positives = 171/246 (69%), Gaps = 1/246 (0%)
 Frame = +2

Query: 74  PIHTPLSFDLINYVNYIAQTTWKAGPTTRFQSISDIRKVLG-VMKDPNNFKLPKRKPLLN 250
           P   PLS DLINY+N    TTW+AG       IS ++K+ G V+  P   KLP R     
Sbjct: 21  PSFHPLSDDLINYINK-QNTTWQAGRNFYNVDISYLKKLCGTVLGGP---KLPGRVAFGE 76

Query: 251 RVRLPTTFDARVQWPKCKSIGEIRDQSNCGSCWAFGAVEAITDRYCIHSNGTQTPRISAE 430
            + LP TFDAR QW  C +IG+IRDQ +CGSCWAFGAVEAI+DR CIH+NG     +SAE
Sbjct: 77  DIDLPETFDAREQWSNCPTIGQIRDQGSCGSCWAFGAVEAISDRTCIHTNGRVNVEVSAE 136

Query: 431 DLLTCCGFRCGDGCNGGFPSGAWHYWVTDGLVTGGEYGAHLGCQDYAFPKCSHHVIGPYP 610
           DLLTCCG +CGDGCNGG+PSGAW +W   GLV+GG Y +H+GC  Y  P C HHV G  P
Sbjct: 137 DLLTCCGIQCGDGCNGGYPSGAWSFWTKKGLVSGGVYNSHVGCLPYTIPPCEHHVNGSRP 196

Query: 611 NCTGEFPTPKCKKACQAGYSKTYAEDKQYGKSSYSVDSNQQAIMQEILTNGPVEAAFSVY 790
            CTGE  TP+C K+C+AGYS +Y EDK +G +SYSV ++ + IM EI  NGPVE AF+V+
Sbjct: 197 PCTGEGDTPRCNKSCEAGYSPSYKEDKHFGYTSYSVSNSVKEIMAEIYKNGPVEGAFTVF 256

Query: 791 ADFPSY 808
           +DF +Y
Sbjct: 257 SDFLTY 262
>sp|P07858|CATB_HUMAN Cathepsin B precursor (Cathepsin B1) (APP secretase) (APPS)
           [Contains: Cathepsin B light chain; Cathepsin B heavy
           chain]
          Length = 339

 Score =  284 bits (727), Expect = 2e-76
 Identities = 133/245 (54%), Positives = 169/245 (68%)
 Frame = +2

Query: 74  PIHTPLSFDLINYVNYIAQTTWKAGPTTRFQSISDIRKVLGVMKDPNNFKLPKRKPLLNR 253
           P   PLS +L+NYVN    TTW+AG       +S ++++ G        K P+R      
Sbjct: 21  PSFHPLSDELVNYVNK-RNTTWQAGHNFYNVDMSYLKRLCGTFL--GGPKPPQRVMFTED 77

Query: 254 VRLPTTFDARVQWPKCKSIGEIRDQSNCGSCWAFGAVEAITDRYCIHSNGTQTPRISAED 433
           ++LP +FDAR QWP+C +I EIRDQ +CGSCWAFGAVEAI+DR CIH+N   +  +SAED
Sbjct: 78  LKLPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAED 137

Query: 434 LLTCCGFRCGDGCNGGFPSGAWHYWVTDGLVTGGEYGAHLGCQDYAFPKCSHHVIGPYPN 613
           LLTCCG  CGDGCNGG+P+ AW++W   GLV+GG Y +H+GC+ Y+ P C HHV G  P 
Sbjct: 138 LLTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPP 197

Query: 614 CTGEFPTPKCKKACQAGYSKTYAEDKQYGKSSYSVDSNQQAIMQEILTNGPVEAAFSVYA 793
           CTGE  TPKC K C+ GYS TY +DK YG +SYSV ++++ IM EI  NGPVE AFSVY+
Sbjct: 198 CTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSVYS 257

Query: 794 DFPSY 808
           DF  Y
Sbjct: 258 DFLLY 262
>sp|P43233|CATB_CHICK Cathepsin B precursor (Cathepsin B1) [Contains: Cathepsin B light
           chain; Cathepsin B heavy chain]
          Length = 340

 Score =  276 bits (706), Expect = 5e-74
 Identities = 130/247 (52%), Positives = 163/247 (65%), Gaps = 1/247 (0%)
 Frame = +2

Query: 71  IPIHTPLSFDLINYVNYIAQTTWKAGPTTRFQSISDIRKVLGVMKDPNNFKLPKRKPLLN 250
           IP + PLS DL+N++N +  TT +AG       +S ++K+ G        K P+R     
Sbjct: 20  IPYYPPLSSDLVNHINKL-NTTGRAGHNFHNTDMSYVKKLCGTFL--GGPKAPERVDFAE 76

Query: 251 RVRLPTTFDARVQWPKCKSIGEIRDQSNCGSCWAFGAVEAITDRYCIHSNGTQTPRISAE 430
            + LP TFD R QWP C +I EIRDQ +CGSCWAFGAVEAI+DR C+H+N   +  +SAE
Sbjct: 77  DMDLPDTFDTRKQWPNCPTISEIRDQGSCGSCWAFGAVEAISDRICVHTNAKVSVEVSAE 136

Query: 431 DLLTCCGFRCGDGCNGGFPSGAWHYWVTDGLVTGGEYGAHLGCQDYAFPKCSHHVIGPYP 610
           DLL+CCGF CG GCNGG+PSGAW YW   GLV+GG Y +H+GC+ Y  P C HHV G  P
Sbjct: 137 DLLSCCGFECGMGCNGGYPSGAWRYWTERGLVSGGLYDSHVGCRAYTIPPCEHHVNGSRP 196

Query: 611 NCTGE-FPTPKCKKACQAGYSKTYAEDKQYGKSSYSVDSNQQAIMQEILTNGPVEAAFSV 787
            CTGE   TP+C + C+ GYS +Y EDK YG +SY V  +++ IM EI  NGPVE AF V
Sbjct: 197 PCTGEGGETPRCSRHCEPGYSPSYKEDKHYGITSYGVPRSEKEIMAEIYKNGPVEGAFIV 256

Query: 788 YADFPSY 808
           Y DF  Y
Sbjct: 257 YEDFLMY 263
>sp|P43157|CYSP_SCHJA Cathepsin B-like cysteine proteinase precursor (Antigen Sj31)
          Length = 342

 Score =  268 bits (685), Expect = 1e-71
 Identities = 126/246 (51%), Positives = 162/246 (65%), Gaps = 5/246 (2%)
 Frame = +2

Query: 86  PLSFDLINYVNYIAQTTWKAGPTTRFQSISDIRKVLGVMKDPNNFKLPKRKPLLNR---- 253
           PLS ++I+++N      WKA  + RF S+ D R ++G  K+    K   R+P ++     
Sbjct: 29  PLSDEMISFINEHPDAGWKADKSDRFHSLDDARILMGARKEDAEMKR-NRRPTVDHHDLN 87

Query: 254 VRLPTTFDARVQWPKCKSIGEIRDQSNCGSCWAFGAVEAITDRYCIHSNGTQTPRISAED 433
           V +P+ FD+R +WP CKSI +IRDQS CGSCWAFGAVEA+TDR CI S G Q+  +SA D
Sbjct: 88  VEIPSQFDSRKKWPHCKSISQIRDQSRCGSCWAFGAVEAMTDRICIQSGGGQSAELSALD 147

Query: 434 LLTCCGFRCGDGCNGGFPSGAWHYWVTDGLVTGGEYGAHLGCQDYAFPKCSHHVIGPYPN 613
           L++CC   CGDGC GGFP  AW YWV  G+VTGG    H GCQ Y FPKC HH  G YP 
Sbjct: 148 LISCCK-DCGDGCQGGFPGVAWDYWVKRGIVTGGSKENHTGCQPYPFPKCEHHTKGKYPA 206

Query: 614 C-TGEFPTPKCKKACQAGYSKTYAEDKQYGKSSYSVDSNQQAIMQEILTNGPVEAAFSVY 790
           C T  + TP+CK+ CQ GY   Y +DK YG  SY+V +N++ I ++I+  GPVEAAF VY
Sbjct: 207 CGTKIYKTPQCKQTCQKGYKTPYEQDKHYGDESYNVQNNEKVIQRDIMMYGPVEAAFDVY 266

Query: 791 ADFPSY 808
            DF +Y
Sbjct: 267 EDFLNY 272
>sp|P25792|CYSP_SCHMA Cathepsin B-like cysteine proteinase precursor (Antigen Sm31)
          Length = 340

 Score =  250 bits (639), Expect = 3e-66
 Identities = 119/246 (48%), Positives = 159/246 (64%), Gaps = 5/246 (2%)
 Frame = +2

Query: 86  PLSFDLINYVNYIAQTTWKAGPTTRFQSISDIRKVLGVMKDPNNFKLPKRKPLLNR---- 253
           PLS D+I+Y+N      W+A  + RF S+ D R  +G  ++  + +  KR+P ++     
Sbjct: 28  PLSDDIISYINEHPNAGWRAEKSNRFHSLDDARIQMGARREEPDLRR-KRRPTVDHNDWN 86

Query: 254 VRLPTTFDARVQWPKCKSIGEIRDQSNCGSCWAFGAVEAITDRYCIHSNGTQTPRISAED 433
           V +P+ FD+R +WP CKSI  IRDQS CGSCW+FGAVEA++DR CI S G Q   +SA D
Sbjct: 87  VEIPSNFDSRKKWPGCKSIATIRDQSRCGSCWSFGAVEAMSDRSCIQSGGKQNVELSAVD 146

Query: 434 LLTCCGFRCGDGCNGGFPSGAWHYWVTDGLVTGGEYGAHLGCQDYAFPKCSHHVIGPYPN 613
           LLTCC   CG GC GG    AW YWV +G+VT      H GC+ Y FPKC HH  G YP 
Sbjct: 147 LLTCCE-SCGLGCEGGILGPAWDYWVKEGIVTASSKENHTGCEPYPFPKCEHHTKGKYPP 205

Query: 614 CTGE-FPTPKCKKACQAGYSKTYAEDKQYGKSSYSVDSNQQAIMQEILTNGPVEAAFSVY 790
           C  + + TP+CK+ CQ  Y   Y +DK  GKSSY+V ++++AI +EI+  GPVEA+F+VY
Sbjct: 206 CGSKIYNTPRCKQTCQRKYKTPYTQDKHRGKSSYNVKNDEKAIQKEIMKYGPVEASFTVY 265

Query: 791 ADFPSY 808
            DF +Y
Sbjct: 266 EDFLNY 271
>sp|P43510|CPR6_CAEEL Cathepsin B-like cysteine proteinase 6 precursor (Cysteine
           protease-related 6)
          Length = 379

 Score =  224 bits (570), Expect = 3e-58
 Identities = 120/249 (48%), Positives = 158/249 (63%), Gaps = 12/249 (4%)
 Frame = +2

Query: 98  DLINYVNYIAQTTWKAGPTTRFQSI-SDIRKVLGVMKDPNNFKLP-KRKPLLNRVR---- 259
           DLI+YVN   Q  W A    RF S+  +  K    +   N+ +L  K K  L++ +    
Sbjct: 45  DLIDYVNE-NQNLWTAKKQRRFSSVYGENDKAKWGLMGVNHVRLSVKGKQHLSKTKDLDL 103

Query: 260 -LPTTFDARVQWPKCKSIGEIRDQSNCGSCWAFGAVEAITDRYCIHSNGTQTPRISAEDL 436
            +P +FD+R  WPKC SI  IRDQS+CGSCWAFGAVEA++DR CI S+G     +SA+DL
Sbjct: 104 DIPESFDSRDNWPKCDSIKVIRDQSSCGSCWAFGAVEAMSDRICIASHGELQVTLSADDL 163

Query: 437 LTCCGFRCGDGCNGGFPSGAWHYWVTDGLVTGGEYGAHLGCQDYAFPKCSHHV----IGP 604
           L+CC   CG GCNGG P  AW YWV DG+VTG  Y A+ GC+ Y FP C HH       P
Sbjct: 164 LSCCK-SCGFGCNGGDPLAAWRYWVKDGIVTGSNYTANNGCKPYPFPPCEHHSKKTHFDP 222

Query: 605 YPNCTGEFPTPKCKKACQAGYS-KTYAEDKQYGKSSYSVDSNQQAIMQEILTNGPVEAAF 781
            P+    +PTPKC+K C + Y+ KTY+EDK +G S+Y V  + +AI +E++T+GP+E AF
Sbjct: 223 CPH--DLYPTPKCEKKCVSDYTDKTYSEDKFFGASAYGVKDDVEAIQKELMTHGPLEIAF 280

Query: 782 SVYADFPSY 808
            VY DF +Y
Sbjct: 281 EVYEDFLNY 289
>sp|P43509|CPR5_CAEEL Cathepsin B-like cysteine proteinase 5 precursor (Cysteine
           protease-related 5)
          Length = 344

 Score =  205 bits (521), Expect = 1e-52
 Identities = 110/245 (44%), Positives = 141/245 (57%), Gaps = 9/245 (3%)
 Frame = +2

Query: 101 LINYVNYIAQTTWKAGPTTRFQSISDIRKVLGVMKDPNNFKLPKRKPLLNRV---RLPTT 271
           LI+YVN  AQ  W AG       +    K+   + D       K + ++       +P  
Sbjct: 32  LIDYVNS-AQKLWTAG-----HQVIPKEKITKKLMDVKYLVPHKDEDIVATEVSDAIPDH 85

Query: 272 FDARVQWPKCKSIGEIRDQSNCGSCWAFGAVEAITDRYCIHSNGTQTPRISAEDLLTCCG 451
           FDAR QWP C SI  IRDQS+CGSCWAF A EAI+DR CI SNG     +S+EDLL+CC 
Sbjct: 86  FDARDQWPNCMSINNIRDQSDCGSCWAFAAAEAISDRTCIASNGAVNTLLSSEDLLSCCT 145

Query: 452 --FRCGDGCNGGFPSGAWHYWVTDGLVTGGEYGAHLGCQDYAFPKCSHHVIG-PYPNCTG 622
             F CG+GC GG+P  AW +WV  GLVTGG Y    GC+ Y+   C   V G  +P C  
Sbjct: 146 GMFSCGNGCEGGYPIQAWKWWVKHGLVTGGSYETQFGCKPYSIAPCGETVNGVKWPACPE 205

Query: 623 EF-PTPKCKKACQA--GYSKTYAEDKQYGKSSYSVDSNQQAIMQEILTNGPVEAAFSVYA 793
           +  PTPKC  +C +   Y+  Y +DK +G ++Y+V    + I  EILTNGP+E AF+VY 
Sbjct: 206 DTEPTPKCVDSCTSKNNYATPYLQDKHFGSTAYAVGKKVEQIQTEILTNGPIEVAFTVYE 265

Query: 794 DFPSY 808
           DF  Y
Sbjct: 266 DFYQY 270
>sp|P25807|CPR1_CAEEL Gut-specific cysteine proteinase precursor
          Length = 329

 Score =  203 bits (517), Expect = 4e-52
 Identities = 97/183 (53%), Positives = 120/183 (65%)
 Frame = +2

Query: 260 LPTTFDARVQWPKCKSIGEIRDQSNCGSCWAFGAVEAITDRYCIHSNGTQTPRISAEDLL 439
           +P TFD+R QW +CKSI  IRDQ+ CGSCWAFGA E I+DR CI + G Q P IS +DLL
Sbjct: 85  VPATFDSRTQWSECKSIKLIRDQATCGSCWAFGAAEMISDRTCIETKGAQQPIISPDDLL 144

Query: 440 TCCGFRCGDGCNGGFPSGAWHYWVTDGLVTGGEYGAHLGCQDYAFPKCSHHVIGPYPNCT 619
           +CCG  CG+GC GG+P  A  +W + G+VTGG+Y    GC+ Y    C+        NC 
Sbjct: 145 SCCGSSCGNGCEGGYPIQALRWWDSKGVVTGGDYHG-AGCKPYPIAPCTS------GNCP 197

Query: 620 GEFPTPKCKKACQAGYSKTYAEDKQYGKSSYSVDSNQQAIMQEILTNGPVEAAFSVYADF 799
            E  TP C  +CQ+GYS  YA+DK +G S+Y+V  N  +I  EI  NGPVEAAFSVY DF
Sbjct: 198 -ESKTPSCSMSCQSGYSTAYAKDKHFGVSAYAVPKNAASIQAEIYANGPVEAAFSVYEDF 256

Query: 800 PSY 808
             Y
Sbjct: 257 YKY 259
  Database: Non-redundant SwissProt sequences
    Posted date:  Dec 6, 2005  7:40 AM
  Number of letters in database: 68,354,980
  Number of sequences in database:  184,735
  
  Database: swissprot.01
    Posted date:  Dec 6, 2005  8:18 AM
  Number of letters in database: 66,202,850
  Number of sequences in database:  184,431
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 99,139,068
Number of Sequences: 369166
Number of extensions: 2191464
Number of successful extensions: 6898
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 6391
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6737
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 7715018400
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)