Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_017_H06
(851 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P53590|SUCB2_PIG Succinyl-CoA ligase [GDP-forming] beta-... 281 2e-75
sp|Q96I99|SUCB2_HUMAN Succinyl-CoA ligase [GDP-forming] bet... 279 6e-75
sp|Q9Z2I8|SUCB2_MOUSE Succinyl-CoA ligase [GDP-forming] bet... 275 1e-73
sp|O82662|SUCB_ARATH Succinyl-CoA ligase [GDP-forming] beta... 252 1e-66
sp|P53589|SUCB2_CAEEL Probable succinyl-CoA ligase [GDP-for... 249 5e-66
sp|O97580|SUCB1_PIG Succinyl-CoA ligase [ADP-forming] beta-... 243 5e-64
sp|Q9Z2I9|SUCB1_MOUSE Succinyl-CoA ligase [ADP-forming] bet... 243 6e-64
sp|Q9P2R7|SUCB1_HUMAN Succinyl-CoA ligase [ADP-forming] bet... 239 5e-63
sp|Q9P567|SUCB_NEUCR Probable succinyl-CoA ligase [GDP-form... 233 5e-61
sp|Q8CPH5|SUCC_STAES Succinyl-CoA synthetase beta chain (SC... 231 2e-60
>sp|P53590|SUCB2_PIG Succinyl-CoA ligase [GDP-forming] beta-chain, mitochondrial
precursor (Succinyl-CoA synthetase, betaG chain)
(SCS-betaG) (GTP-specific succinyl-CoA synthetase beta
subunit)
Length = 433
Score = 281 bits (718), Expect = 2e-75
Identities = 141/231 (61%), Positives = 178/231 (77%)
Frame = -1
Query: 845 SQCDEIAQHLLFTSKQQIDEVGKQLRGLFDLFLQHDCTQIEINPFGVTPGGQIVCFDAKL 666
SQ +A++L F Q ++ Q++ L++LFL+ D TQ+E+NPFG TP GQ+VCFDAK+
Sbjct: 203 SQAQRMAENLGFLGPLQ-NQAADQIKKLYNLFLKIDATQVEVNPFGETPEGQVVCFDAKI 261
Query: 665 NFDDNAAFRQREIFSLHDPVAEEQDpreIEAAQNGLNYIGLHGNIGCVVNGAGLAMATMD 486
NFDDNA FRQ++IF++ D E +P E EAA+ L YIGL GNI C VNGAGLAMAT D
Sbjct: 262 NFDDNAEFRQKDIFAMDDK--SENEPIENEAAKYDLKYIGLDGNIACFVNGAGLAMATCD 319
Query: 485 IVKLNGGTPANFLDLGGGVTASQVKQAFHILTGDPQVKSIFINIFGGIVNCGTIAEGLTA 306
I+ LNGG PANFLDLGGGV SQV QAF +LT DP+V++I +NIFGGIVNC IA G+T
Sbjct: 320 IIFLNGGKPANFLDLGGGVKESQVYQAFKLLTADPKVEAILVNIFGGIVNCAIIANGITK 379
Query: 305 ACRDVELKVPLIVRLEGTNVDSARRILSNSGIPMKMSTDLDEAAKMAVHSV 153
ACR++ELKVPL+VRLEGTNV A+ IL+NSG+P+ + DL++AAK AV SV
Sbjct: 380 ACRELELKVPLVVRLEGTNVHEAQNILTNSGLPITSAVDLEDAAKKAVASV 430
>sp|Q96I99|SUCB2_HUMAN Succinyl-CoA ligase [GDP-forming] beta-chain, mitochondrial
precursor (Succinyl-CoA synthetase, betaG chain)
(SCS-betaG) (GTP-specific succinyl-CoA synthetase beta
subunit)
Length = 432
Score = 279 bits (714), Expect = 6e-75
Identities = 140/232 (60%), Positives = 178/232 (76%)
Frame = -1
Query: 845 SQCDEIAQHLLFTSKQQIDEVGKQLRGLFDLFLQHDCTQIEINPFGVTPGGQIVCFDAKL 666
SQ +A++L F + + Q+ L++LFL+ D TQ+E+NPFG TP GQ+VCFDAK+
Sbjct: 202 SQAQRMAENLGFVGPLK-SQAADQITKLYNLFLKIDATQVEVNPFGETPEGQVVCFDAKI 260
Query: 665 NFDDNAAFRQREIFSLHDPVAEEQDpreIEAAQNGLNYIGLHGNIGCVVNGAGLAMATMD 486
NFDDNA FRQ++IF++ D E +P E EAA+ L YIGL GNI C VNGAGLAMAT D
Sbjct: 261 NFDDNAEFRQKDIFAMDDK--SENEPIENEAAKYDLKYIGLDGNIACFVNGAGLAMATCD 318
Query: 485 IVKLNGGTPANFLDLGGGVTASQVKQAFHILTGDPQVKSIFINIFGGIVNCGTIAEGLTA 306
I+ LNGG PANFLDLGGGV +QV QAF +LT DP+V++I +NIFGGIVNC IA G+T
Sbjct: 319 IIFLNGGKPANFLDLGGGVKEAQVYQAFKLLTADPKVEAILVNIFGGIVNCAIIANGITK 378
Query: 305 ACRDVELKVPLIVRLEGTNVDSARRILSNSGIPMKMSTDLDEAAKMAVHSVA 150
ACR++ELKVPL+VRLEGTNV A++IL+NSG+P+ + DL++AAK AV SVA
Sbjct: 379 ACRELELKVPLVVRLEGTNVQEAQKILNNSGLPITSAIDLEDAAKKAVASVA 430
>sp|Q9Z2I8|SUCB2_MOUSE Succinyl-CoA ligase [GDP-forming] beta-chain, mitochondrial
precursor (Succinyl-CoA synthetase, betaG chain)
(SCS-betaG) (GTP-specific succinyl-CoA synthetase beta
subunit)
Length = 404
Score = 275 bits (703), Expect = 1e-73
Identities = 138/232 (59%), Positives = 176/232 (75%)
Frame = -1
Query: 845 SQCDEIAQHLLFTSKQQIDEVGKQLRGLFDLFLQHDCTQIEINPFGVTPGGQIVCFDAKL 666
SQ +A++L F + ++ Q+ L+ LFL+ D TQ+E+NPFG TP GQ+VCFDAK+
Sbjct: 174 SQAQRMAENLGFLGSLK-NQAADQITKLYHLFLKIDATQVEVNPFGETPEGQVVCFDAKI 232
Query: 665 NFDDNAAFRQREIFSLHDPVAEEQDpreIEAAQNGLNYIGLHGNIGCVVNGAGLAMATMD 486
NFDDNA FRQ++IF++ D E +P E EAA+ L YIGL GNI C VNGAGLAMAT D
Sbjct: 233 NFDDNAEFRQKDIFAMDDK--SENEPIENEAARYDLKYIGLDGNIACFVNGAGLAMATCD 290
Query: 485 IVKLNGGTPANFLDLGGGVTASQVKQAFHILTGDPQVKSIFINIFGGIVNCGTIAEGLTA 306
I+ LNGG PANFLDLGGGV +QV +AF +LT DP+V++I +NIFGGIVNC IA G+T
Sbjct: 291 IIFLNGGKPANFLDLGGGVKEAQVYEAFKLLTSDPKVEAILVNIFGGIVNCAIIANGITK 350
Query: 305 ACRDVELKVPLIVRLEGTNVDSARRILSNSGIPMKMSTDLDEAAKMAVHSVA 150
ACR++ELKVPL+VRLEGTNV A+ IL +SG+P+ + DL++AAK AV SVA
Sbjct: 351 ACRELELKVPLVVRLEGTNVQEAQNILKSSGLPITSAVDLEDAAKKAVASVA 402
>sp|O82662|SUCB_ARATH Succinyl-CoA ligase [GDP-forming] beta-chain, mitochondrial
precursor (Succinyl-CoA synthetase, beta chain)
(SCS-beta)
Length = 421
Score = 252 bits (643), Expect = 1e-66
Identities = 123/210 (58%), Positives = 161/210 (76%)
Frame = -1
Query: 779 KQLRGLFDLFLQHDCTQIEINPFGVTPGGQIVCFDAKLNFDDNAAFRQREIFSLHDPVAE 600
+Q++ L++LF + DCT +EINP T Q+V DAKLNFDDNAAFRQ+E+F++ DP E
Sbjct: 213 EQVKKLYELFRKTDCTMLEINPLAETSTNQLVAADAKLNFDDNAAFRQKEVFAMRDPTQE 272
Query: 599 EQDpreIEAAQNGLNYIGLHGNIGCVVNGAGLAMATMDIVKLNGGTPANFLDLGGGVTAS 420
Dpre+ AA+ LNYIGL G IGC+VNGAGLAMATMDI+KL+GGTPANFLD+GG +
Sbjct: 273 --DpreVAAAKVDLNYIGLDGEIGCMVNGAGLAMATMDIIKLHGGTPANFLDVGGNASEH 330
Query: 419 QVKQAFHILTGDPQVKSIFINIFGGIVNCGTIAEGLTAACRDVELKVPLIVRLEGTNVDS 240
QV +AF ILT D +VK+I +NIFGGI+ C IA G+ A ++V LKVP++VRLEGTNV+
Sbjct: 331 QVVEAFKILTSDDKVKAILVNIFGGIMKCDVIASGIVNAAKEVALKVPVVVRLEGTNVEQ 390
Query: 239 ARRILSNSGIPMKMSTDLDEAAKMAVHSVA 150
+RIL SG+ + + DLD+AA+ AV ++A
Sbjct: 391 GKRILKESGMKLITADDLDDAAEKAVKALA 420
>sp|P53589|SUCB2_CAEEL Probable succinyl-CoA ligase [GDP-forming] beta-chain,
mitochondrial precursor (Succinyl-CoA synthetase, beta
chain) (SCS-beta)
Length = 415
Score = 249 bits (637), Expect = 5e-66
Identities = 126/233 (54%), Positives = 168/233 (72%)
Frame = -1
Query: 851 TKSQCDEIAQHLLFTSKQQIDEVGKQLRGLFDLFLQHDCTQIEINPFGVTPGGQIVCFDA 672
T+ Q +IA+ L F K I ++++ L+DLF+ D TQ+EINP T G++ C DA
Sbjct: 184 TEGQSLKIAKDLQFEGKL-IGVAAQEIKRLYDLFIAVDATQVEINPLVETADGRVFCVDA 242
Query: 671 KLNFDDNAAFRQREIFSLHDPVAEEQDpreIEAAQNGLNYIGLHGNIGCVVNGAGLAMAT 492
K+NFDD+AA+RQ+EIF+ EE Dpre++A Q LNYIG+ GNI C+VNGAGLAMAT
Sbjct: 243 KMNFDDSAAYRQKEIFAYE--TFEEHDpreVDAHQFNLNYIGMDGNIACLVNGAGLAMAT 300
Query: 491 MDIVKLNGGTPANFLDLGGGVTASQVKQAFHILTGDPQVKSIFINIFGGIVNCGTIAEGL 312
MD++KL+GG PANFLD+GG VT V A I+T DP+VK + INIFGGIVNC TIA G+
Sbjct: 301 MDLIKLHGGEPANFLDVGGAVTEDAVFNAVRIITSDPRVKCVLINIFGGIVNCATIANGV 360
Query: 311 TAACRDVELKVPLIVRLEGTNVDSARRILSNSGIPMKMSTDLDEAAKMAVHSV 153
+A + L VP++VRLEGTNVD+A++I+ SG+ + + +LDEAA AV S+
Sbjct: 361 VSAVNKIGLNVPMVVRLEGTNVDAAKQIMKKSGLKILTANNLDEAAAKAVSSL 413
>sp|O97580|SUCB1_PIG Succinyl-CoA ligase [ADP-forming] beta-chain, mitochondrial
precursor (Succinyl-CoA synthetase, betaA chain)
(SCS-betaA) (ATP-specific succinyl-CoA synthetase beta
subunit)
Length = 425
Score = 243 bits (620), Expect = 5e-64
Identities = 119/229 (51%), Positives = 165/229 (72%)
Frame = -1
Query: 848 KSQCDEIAQHLLFTSKQQIDEVGKQLRGLFDLFLQHDCTQIEINPFGVTPGGQIVCFDAK 669
K Q +AQ + F +D + + L++LFL++D T +EINP G ++C DAK
Sbjct: 178 KEQAVRLAQKMGFPPSI-VDSAAENMIKLYNLFLKYDATMVEINPMVEDSDGAVLCMDAK 236
Query: 668 LNFDDNAAFRQREIFSLHDPVAEEQDpreIEAAQNGLNYIGLHGNIGCVVNGAGLAMATM 489
+NFD N+A+RQ++IF L D E D R+ +AA+ LNYIGL GNIGC+VNGAGLAMATM
Sbjct: 237 INFDSNSAYRQKKIFDLQDWTQE--DERDKDAAKANLNYIGLDGNIGCLVNGAGLAMATM 294
Query: 488 DIVKLNGGTPANFLDLGGGVTASQVKQAFHILTGDPQVKSIFINIFGGIVNCGTIAEGLT 309
DI+KL+GGTPANFLD+GGG T QV +AF ++T D +V SI +NIFGGI+ C IA+G+
Sbjct: 295 DIIKLHGGTPANFLDVGGGATVHQVTEAFKLITSDKKVLSILVNIFGGIMRCDVIAQGIV 354
Query: 308 AACRDVELKVPLIVRLEGTNVDSARRILSNSGIPMKMSTDLDEAAKMAV 162
A +D+E+K+P++VRL+GT VD A+ ++++SG+ + DLDEAAKM V
Sbjct: 355 MAVKDLEIKIPVVVRLQGTRVDDAKALIADSGLKILACDDLDEAAKMVV 403
>sp|Q9Z2I9|SUCB1_MOUSE Succinyl-CoA ligase [ADP-forming] beta-chain, mitochondrial
precursor (Succinyl-CoA synthetase, betaA chain)
(SCS-betaA) (ATP-specific succinyl-CoA synthetase beta
subunit)
Length = 463
Score = 243 bits (619), Expect = 6e-64
Identities = 116/229 (50%), Positives = 168/229 (73%)
Frame = -1
Query: 848 KSQCDEIAQHLLFTSKQQIDEVGKQLRGLFDLFLQHDCTQIEINPFGVTPGGQIVCFDAK 669
K Q +AQ + F S +D + + L++LFL++D T +EINP G+++C DAK
Sbjct: 216 KEQAVTLAQKMGFPSNI-VDSAAENMIKLYNLFLKYDATMVEINPMVEDSDGKVLCMDAK 274
Query: 668 LNFDDNAAFRQREIFSLHDPVAEEQDpreIEAAQNGLNYIGLHGNIGCVVNGAGLAMATM 489
+NFD N+A+RQ++IF L D ++D R+ EAA +NYIGL G+IGC+VNGAGLAMATM
Sbjct: 275 INFDSNSAYRQKKIFDLQD--WSQEDERDKEAANADINYIGLDGSIGCLVNGAGLAMATM 332
Query: 488 DIVKLNGGTPANFLDLGGGVTASQVKQAFHILTGDPQVKSIFINIFGGIVNCGTIAEGLT 309
DI+KL+GGTPANFLD+GGG T QV +AF ++T D +V++I +NIFGGI+ C IA+G+
Sbjct: 333 DIIKLHGGTPANFLDVGGGATVQQVTEAFKLITSDKKVQAILVNIFGGIMRCDVIAQGIV 392
Query: 308 AACRDVELKVPLIVRLEGTNVDSARRILSNSGIPMKMSTDLDEAAKMAV 162
A +D+E+++P++VRL+GT VD A+ ++++SG+ + DLDEAAKM V
Sbjct: 393 MAVKDLEIRIPVVVRLQGTRVDDAKALIADSGLKILACDDLDEAAKMVV 441
>sp|Q9P2R7|SUCB1_HUMAN Succinyl-CoA ligase [ADP-forming] beta-chain, mitochondrial
precursor (Succinyl-CoA synthetase, betaA chain)
(SCS-betaA) (ATP-specific succinyl-CoA synthetase beta
subunit)
Length = 463
Score = 239 bits (611), Expect = 5e-63
Identities = 117/229 (51%), Positives = 165/229 (72%)
Frame = -1
Query: 848 KSQCDEIAQHLLFTSKQQIDEVGKQLRGLFDLFLQHDCTQIEINPFGVTPGGQIVCFDAK 669
K Q ++AQ + F ++ + + L+ LFL++D T IEINP G ++C DAK
Sbjct: 216 KEQALQLAQKMGFPPNI-VESAAENMVKLYSLFLKYDATMIEINPMVEDSDGAVLCMDAK 274
Query: 668 LNFDDNAAFRQREIFSLHDPVAEEQDpreIEAAQNGLNYIGLHGNIGCVVNGAGLAMATM 489
+NFD N+A+RQ++IF L D E D R+ +AA+ LNYIGL GNIGC+VNGAGLAMATM
Sbjct: 275 INFDSNSAYRQKKIFDLQDWTQE--DERDKDAAKANLNYIGLDGNIGCLVNGAGLAMATM 332
Query: 488 DIVKLNGGTPANFLDLGGGVTASQVKQAFHILTGDPQVKSIFINIFGGIVNCGTIAEGLT 309
DI+KL+GGTPANFLD+GGG T QV +AF ++T D +V +I +NIFGGI+ C IA+G+
Sbjct: 333 DIIKLHGGTPANFLDVGGGATVHQVTEAFKLITSDKKVLAILVNIFGGIMRCDVIAQGIV 392
Query: 308 AACRDVELKVPLIVRLEGTNVDSARRILSNSGIPMKMSTDLDEAAKMAV 162
A +D+E+K+P++VRL+GT VD A+ ++++SG+ + DLDEAA+M V
Sbjct: 393 MAVKDLEIKIPVVVRLQGTRVDDAKALIADSGLKILACDDLDEAARMVV 441
>sp|Q9P567|SUCB_NEUCR Probable succinyl-CoA ligase [GDP-forming] beta-chain,
mitochondrial precursor (Succinyl-CoA synthetase, beta
chain) (SCS-beta)
Length = 447
Score = 233 bits (594), Expect = 5e-61
Identities = 116/230 (50%), Positives = 162/230 (70%)
Frame = -1
Query: 851 TKSQCDEIAQHLLFTSKQQIDEVGKQLRGLFDLFLQHDCTQIEINPFGVTPGGQIVCFDA 672
T +IA L F S+Q ++E ++ L+ +F + D TQIEINP T +++ DA
Sbjct: 199 TDEMARDIATKLGF-SEQCVEEAKDTIQKLYKIFCEKDATQIEINPLSETSDHKVMAMDA 257
Query: 671 KLNFDDNAAFRQREIFSLHDPVAEEQDpreIEAAQNGLNYIGLHGNIGCVVNGAGLAMAT 492
K FDDNA FRQ +IF L D E DP E+ AAQ GLN+I L G+IGC+VNGAGLAMAT
Sbjct: 258 KFGFDDNADFRQPDIFKLRDTTQE--DPDEVRAAQAGLNFIKLDGDIGCLVNGAGLAMAT 315
Query: 491 MDIVKLNGGTPANFLDLGGGVTASQVKQAFHILTGDPQVKSIFINIFGGIVNCGTIAEGL 312
MDI+KLNGG PANFLD+GGG T + +++AF ++T DP+V +IF+NIFGGIV C IA GL
Sbjct: 316 MDIIKLNGGQPANFLDVGGGATPAAIREAFELITSDPKVTAIFVNIFGGIVRCDAIAHGL 375
Query: 311 TAACRDVELKVPLIVRLEGTNVDSARRILSNSGIPMKMSTDLDEAAKMAV 162
+ ++LK+P+I RL+GTN+++AR+++++SG+ + DL AA+ +V
Sbjct: 376 INTVKSLDLKIPIIARLQGTNMEAARQLINDSGMKIFSIDDLQSAAEKSV 425
>sp|Q8CPH5|SUCC_STAES Succinyl-CoA synthetase beta chain (SCS-beta)
sp|Q5HPU5|SUCC_STAEQ Succinyl-CoA synthetase beta chain (SCS-beta)
Length = 388
Score = 231 bits (589), Expect = 2e-60
Identities = 113/217 (52%), Positives = 155/217 (71%)
Frame = -1
Query: 803 KQQIDEVGKQLRGLFDLFLQHDCTQIEINPFGVTPGGQIVCFDAKLNFDDNAAFRQREIF 624
K+ + + K L L+++F++ DC+ +EINP T GQ++ DAKLNFDDNA FR ++I
Sbjct: 171 KESVGKATKFLLALYNVFIEKDCSIVEINPLVTTGDGQVLALDAKLNFDDNALFRHKDIL 230
Query: 623 SLHDPVAEEQDpreIEAAQNGLNYIGLHGNIGCVVNGAGLAMATMDIVKLNGGTPANFLD 444
L D EE+DP+EIEA++ L+YI L G+IGC+VNGAGLAMATMD + GG PANFLD
Sbjct: 231 ELRD--LEEEDPKEIEASKYDLSYIALDGDIGCMVNGAGLAMATMDTINHFGGNPANFLD 288
Query: 443 LGGGVTASQVKQAFHILTGDPQVKSIFINIFGGIVNCGTIAEGLTAACRDVELKVPLIVR 264
+GGG T +V +AF I+ GD VK IF+NIFGGI+ C IAEG+ AA ++VEL +PL+VR
Sbjct: 289 VGGGATKEKVTEAFKIILGDDNVKGIFVNIFGGIMKCDVIAEGIVAAVKEVELTLPLVVR 348
Query: 263 LEGTNVDSARRILSNSGIPMKMSTDLDEAAKMAVHSV 153
LEGTNV+ + IL+ SG+ ++ + + E A+ V V
Sbjct: 349 LEGTNVERGKAILNESGLAIEPAATMAEGAQKIVKLV 385
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 107,318,861
Number of Sequences: 369166
Number of extensions: 2460575
Number of successful extensions: 7385
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 6929
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 7288
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 8390082510
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)