Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_017_G13
(521 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P08799|MYS2_DICDI Myosin II heavy chain, non muscle 46 6e-05
sp|O02365|IFA2_CAEEL Intermediate filament protein ifa-2 (I... 42 0.001
sp|Q59037|SMC_METJA Chromosome partition protein smc homolog 40 0.003
sp|Q96T51|RUFY1_HUMAN RUN and FYVE domain containing protei... 40 0.003
sp|Q68D86|CR014_HUMAN Hypothetical protein C18orf14 40 0.003
sp|P35241|RADI_HUMAN Radixin 40 0.004
sp|P24339|CUT7_SCHPO Kinesin-like protein cut7 (Cell untime... 40 0.004
sp|Q12267|SMC4_YEAST Structural maintenance of chromosome 4 40 0.004
sp|P26044|RADI_PIG Radixin (Moesin B) 39 0.006
sp|P26043|RADI_MOUSE Radixin (ESP10) 39 0.006
>sp|P08799|MYS2_DICDI Myosin II heavy chain, non muscle
Length = 2116
Score = 45.8 bits (107), Expect = 6e-05
Identities = 35/108 (32%), Positives = 59/108 (54%), Gaps = 10/108 (9%)
Frame = +2
Query: 122 EKLSKNVSEFQIILPDLEKKNC-------HLEKLISDIKQTMK-DRTTNYEEEKKYL--E 271
+KL + +SE Q L + KN HLE +++K ++ ++ EKK L E
Sbjct: 1230 KKLEQELSEVQTQLSEANNKNVNSDSTNKHLETSFNNLKLELEAEQKAKQALEKKRLGLE 1289
Query: 272 MQLENSSTKLEWVKKEKQGLEEMKEDLMKEIEKYKDKYDLTQLEEKLA 415
+L++ + +LE KK+K+ E+ K DL KE+ + KD Q+EE++A
Sbjct: 1290 SELKHVNEQLEEEKKQKESNEKRKVDLEKEVSELKD-----QIEEEVA 1332
Score = 38.1 bits (87), Expect = 0.013
Identities = 27/90 (30%), Positives = 45/90 (50%), Gaps = 8/90 (8%)
Frame = +2
Query: 173 EKKNCHLEKLISDIKQTMKDRTTNYEE---EKKYLEMQLENSSTKLEWVKKEKQGLEEMK 343
EKK L + ++K+ ++D ++ K+ LE++LE +LE + + LE+ K
Sbjct: 1670 EKKIKSLVAEVDEVKEQLEDEILAKDKLVKAKRALEVELEEVRDQLEEEEDSRSELEDSK 1729
Query: 344 EDLMKEIEKYKDKYDL-----TQLEEKLAK 418
L E+E K KYD T+L+E K
Sbjct: 1730 RRLTTEVEDIKKKYDAEVEQNTKLDEAKKK 1759
Score = 37.0 bits (84), Expect = 0.029
Identities = 38/124 (30%), Positives = 64/124 (51%), Gaps = 10/124 (8%)
Frame = +2
Query: 113 DCSEKLSKNVSEFQIILPDLE----KKNCHLEKLISDIKQTMKDRTTNYEEEKKYLEMQL 280
D + L E +I + D+E +K LE L + K++++++ + EEE + E +L
Sbjct: 884 DSKDALEAQKRELEIRVEDMESELDEKKLALENLQNQ-KRSVEEKVRDLEEELQE-EQKL 941
Query: 281 ENSSTKLEWVKKEKQGLEEMKE------DLMKEIEKYKDKYDLTQLEEKLAK*FYFEV*K 442
N+ KL+ KK ++ LEEMK D + +EK KD +L + E+L + F E
Sbjct: 942 RNTLEKLK--KKYEEELEEMKRVNDGQSDTISRLEKIKD--ELQKEVEELTESFSEESKD 997
Query: 443 KMIL 454
K +L
Sbjct: 998 KGVL 1001
Score = 31.6 bits (70), Expect = 1.2
Identities = 20/86 (23%), Positives = 45/86 (52%), Gaps = 10/86 (11%)
Frame = +2
Query: 191 LEKLISDIKQTMKD---RTTNYEEEKKYLEMQLENSSTKLE-------WVKKEKQGLEEM 340
LE I +++ ++ + T ++ KK LE +++N ++E ++KEK+ LE
Sbjct: 1844 LEDQIDELRSKLEQEQAKATQADKSKKTLEGEIDNLRAQIEDEGKIKMRLEKEKRALEGE 1903
Query: 341 KEDLMKEIEKYKDKYDLTQLEEKLAK 418
E+L + +E+ +D + ++L +
Sbjct: 1904 LEELRETVEEAEDSKSEAEQSKRLVE 1929
Score = 30.4 bits (67), Expect = 2.7
Identities = 26/92 (28%), Positives = 39/92 (42%), Gaps = 14/92 (15%)
Frame = +2
Query: 173 EKKNCHLEKLISDIKQTMKDRTT---NYEEEKKYLEMQLENSSTKLEWVKKEKQGLE--- 334
E N L+ +++ + T N E+ KK LE QL + +L+ KK + LE
Sbjct: 1058 EAANKKLQGEYTELNEKFNSEVTARSNVEKSKKTLESQLVAVNNELDEEKKNRDALEKKK 1117
Query: 335 --------EMKEDLMKEIEKYKDKYDLTQLEE 406
EMK+ L + K YDL +E
Sbjct: 1118 KALDAMLEEMKDQLESTGGEKKSLYDLKVKQE 1149
>sp|O02365|IFA2_CAEEL Intermediate filament protein ifa-2 (Intermediate filament protein
A2) (IF-A2) (Cel IF A2)
Length = 581
Score = 41.6 bits (96), Expect = 0.001
Identities = 29/106 (27%), Positives = 50/106 (47%), Gaps = 7/106 (6%)
Frame = +2
Query: 122 EKLSKNVSEFQIILPDLEKKNCHLEKLISDIKQTMKDRTTNYEEEKKYLEMQLENSSTKL 301
++L SE + L DLE +N LEK I D+ ++D +YE + Q+ +
Sbjct: 330 KRLRNQTSELRQKLSDLESRNLLLEKQIEDLNYQLEDDQRSYEAALNDKDAQIRKLREEC 389
Query: 302 EWVKKEKQGLEEMKEDLMKEIEKYKDKYD-------LTQLEEKLAK 418
+ + E Q L + K+ L E++ Y+ + L QL EK+ +
Sbjct: 390 QALMVELQMLLDTKQTLDGELKVYRQMLEGNSEGNGLRQLVEKVVR 435
>sp|Q59037|SMC_METJA Chromosome partition protein smc homolog
Length = 1169
Score = 40.4 bits (93), Expect = 0.003
Identities = 24/98 (24%), Positives = 55/98 (56%), Gaps = 7/98 (7%)
Frame = +2
Query: 113 DCSEKLSKNVSEFQIILPDLE-------KKNCHLEKLISDIKQTMKDRTTNYEEEKKYLE 271
+ +++++KN +E + +L +KN +EK IK+ ++ T + + K L
Sbjct: 395 EIADEIAKNQNELYRLKKELNDLDNLINRKNFEIEKNNEMIKKLKEELETVEDVDTKPLY 454
Query: 272 MQLENSSTKLEWVKKEKQGLEEMKEDLMKEIEKYKDKY 385
++LEN + ++E+ K+ + LEE K++L ++++ +Y
Sbjct: 455 LELENLNVEIEFSKRGIKELEEKKKELQAKLDELHAEY 492
Score = 32.3 bits (72), Expect = 0.70
Identities = 22/72 (30%), Positives = 38/72 (52%)
Frame = +2
Query: 152 QIILPDLEKKNCHLEKLISDIKQTMKDRTTNYEEEKKYLEMQLENSSTKLEWVKKEKQGL 331
+I++P +E+ N + +LI+ K ++ + Y+E + LE + E + K + L
Sbjct: 832 EILIPKIEELNKKVSELINK-KVILEKNISFYKESIEKNLSILEEKRKRYEELAKNLKEL 890
Query: 332 EEMKEDLMKEIE 367
E KE L KEIE
Sbjct: 891 TEKKEQLEKEIE 902
Score = 30.8 bits (68), Expect = 2.0
Identities = 27/87 (31%), Positives = 42/87 (48%), Gaps = 3/87 (3%)
Frame = +2
Query: 122 EKLSKNVSEFQIILPDLEKKNCHLEKLISDIKQTMKDRTTNYEE---EKKYLEMQLENSS 292
E+L+KN+ E LEK+ LE+ +I + ++D E EK E +LE
Sbjct: 881 EELAKNLKELTEKKEQLEKEIETLERERREILRKVRDIENRINELMVEKAKYESKLEEEE 940
Query: 293 TKLEWVKKEKQGLEEMKEDLMKEIEKY 373
KL +K E K+D+ +E+E Y
Sbjct: 941 RKLYLCEKVDVSKELEKKDI-EELEIY 966
Score = 29.6 bits (65), Expect = 4.6
Identities = 19/91 (20%), Positives = 45/91 (49%)
Frame = +2
Query: 110 QDCSEKLSKNVSEFQIILPDLEKKNCHLEKLISDIKQTMKDRTTNYEEEKKYLEMQLENS 289
++ E ++ +S+ + I ++E L +I+++ + + + K LE+++EN
Sbjct: 253 KNLEELKNEFLSKVREIDVEIENLKLRLNNIINELNEKGNEEVLELHKSIKELEVEIEND 312
Query: 290 STKLEWVKKEKQGLEEMKEDLMKEIEKYKDK 382
L+ E + +E E+ KEI++ + K
Sbjct: 313 KKVLDSSINELKKVEVEIENKKKEIKETQKK 343
Score = 29.3 bits (64), Expect = 6.0
Identities = 26/96 (27%), Positives = 47/96 (48%), Gaps = 12/96 (12%)
Frame = +2
Query: 113 DCSEKLSK-NVSEFQIILPDLEKKNCHLE----KLISDI-------KQTMKDRTTNYEEE 256
D S++L K ++ E +I + +LE + LE + I D K+ ++ R +E
Sbjct: 950 DVSKELEKKDIEELEIYIGELENEIKSLEPVNMRAIEDYNYVAERYKELIEKRKEYERDE 1009
Query: 257 KKYLEMQLENSSTKLEWVKKEKQGLEEMKEDLMKEI 364
KKYL++ E + K E + + + E++ KEI
Sbjct: 1010 KKYLQLMEELENKKKEVFMEVFNKVAKNFEEVYKEI 1045
>sp|Q96T51|RUFY1_HUMAN RUN and FYVE domain containing protein 1 (FYVE-finger protein EIP1)
(Zinc finger FYVE domain containing protein 12)
Length = 600
Score = 40.4 bits (93), Expect = 0.003
Identities = 25/100 (25%), Positives = 51/100 (51%), Gaps = 11/100 (11%)
Frame = +2
Query: 110 QDCSEKLSKNVSEFQIILPDLEKKNCHLEKLIS-----------DIKQTMKDRTTNYEEE 256
++ + LS V + Q + LEK N L++ +S + +Q + E
Sbjct: 204 EELNRHLSCTVGDLQTKIDGLEKTNSKLQEELSAATDRICSLQEEQQQLREQNELIRERS 263
Query: 257 KKYLEMQLENSSTKLEWVKKEKQGLEEMKEDLMKEIEKYK 376
+K +E+ +++ +LE K+ +QGL+EM D+ K++++ K
Sbjct: 264 EKSVEITKQDTKVELETYKQTRQGLDEMYSDVWKQLKEEK 303
>sp|Q68D86|CR014_HUMAN Hypothetical protein C18orf14
Length = 513
Score = 40.0 bits (92), Expect = 0.003
Identities = 34/100 (34%), Positives = 54/100 (54%), Gaps = 9/100 (9%)
Frame = +2
Query: 110 QDCSEKLSKNVSEFQIILPDLEKKNCHLEKLISDIKQTMKDRTTNYE---EEKKYLE-MQ 277
++ E KNV EF I+L + N +++L +IK+ K + + E + LE +Q
Sbjct: 300 EELKESKPKNVKEFDILLG---QHNDEMQELSGNIKEESKSQNSKDRVICELRAELERLQ 356
Query: 278 LENSST--KLEWVKKEKQGLEEMKEDL---MKEIEKYKDK 382
EN+S K E +++EKQGLE L +KE+E+ DK
Sbjct: 357 AENTSEWDKREILEREKQGLERENRRLKIQVKEMEELLDK 396
>sp|P35241|RADI_HUMAN Radixin
Length = 583
Score = 39.7 bits (91), Expect = 0.004
Identities = 23/69 (33%), Positives = 39/69 (56%), Gaps = 2/69 (2%)
Frame = +2
Query: 218 QTMKDRTTNYEEEKKYLEMQLENSSTKLEWVKKEKQGLEEMKEDLMKEIEKYKDKYDLTQ 397
Q MK + + +K+ QLEN K E +KEK+ +E KE+LM+ +++ +++ Q
Sbjct: 303 QQMKAQAREEKHQKQLERAQLENEKKKREIAEKEKERIEREKEELMERLKQIEEQTIKAQ 362
Query: 398 --LEEKLAK 418
LEE+ K
Sbjct: 363 KELEEQTRK 371
>sp|P24339|CUT7_SCHPO Kinesin-like protein cut7 (Cell untimely torn protein 7)
Length = 1085
Score = 39.7 bits (91), Expect = 0.004
Identities = 24/60 (40%), Positives = 38/60 (63%)
Frame = +2
Query: 218 QTMKDRTTNYEEEKKYLEMQLENSSTKLEWVKKEKQGLEEMKEDLMKEIEKYKDKYDLTQ 397
Q + +++E + L++QL NSST+LE VK E E++K +L+ EIEK K KY+ +
Sbjct: 503 QYVSKSNQEHKKEVEALQLQLVNSSTELESVKSEN---EKLKNELVLEIEKRK-KYETNE 558
>sp|Q12267|SMC4_YEAST Structural maintenance of chromosome 4
Length = 1418
Score = 39.7 bits (91), Expect = 0.004
Identities = 24/94 (25%), Positives = 49/94 (52%), Gaps = 7/94 (7%)
Frame = +2
Query: 122 EKLSKNVSEFQIILPDLEKKNCHLEKLISDIKQTMKDRTTN-------YEEEKKYLEMQL 280
E+L +E + + DL + ++ DIK ++KD+T N +E+E + ++QL
Sbjct: 506 EELRGQQTEHETEIKDLTQLLEKERSILDDIKLSLKDKTKNISAEIIRHEKELEPWDLQL 565
Query: 281 ENSSTKLEWVKKEKQGLEEMKEDLMKEIEKYKDK 382
+ ++++ + E LEE + L K +E ++K
Sbjct: 566 QEKESQIQLAESELSLLEETQAKLKKNVETLEEK 599
>sp|P26044|RADI_PIG Radixin (Moesin B)
Length = 583
Score = 39.3 bits (90), Expect = 0.006
Identities = 23/69 (33%), Positives = 38/69 (55%), Gaps = 2/69 (2%)
Frame = +2
Query: 218 QTMKDRTTNYEEEKKYLEMQLENSSTKLEWVKKEKQGLEEMKEDLMKEIEKYKDKYDLTQ 397
Q MK + + +K+ QLEN K E +KEK+ +E KE+LM+ + + +++ Q
Sbjct: 303 QQMKAQAREEKHQKQLERAQLENEKKKREIAEKEKERIEREKEELMERLRQIEEQTMKAQ 362
Query: 398 --LEEKLAK 418
LEE+ K
Sbjct: 363 KELEEQTRK 371
Score = 34.3 bits (77), Expect = 0.19
Identities = 33/113 (29%), Positives = 58/113 (51%), Gaps = 4/113 (3%)
Frame = +2
Query: 119 SEKLSKNVSEFQIILPDLEKKNCHLEKLISDIKQTMKDRTTNYEEEKKYLEMQLENSSTK 298
+EK + ++E + + EK+ +E+L +QTMK + E+ +K LE+ E K
Sbjct: 325 NEKKKREIAEKEKERIEREKEEL-MERLRQIEEQTMKAQKELEEQTRKALELDQERKRAK 383
Query: 299 --LEWVKKEKQGLEEMKEDLMKE-IEKYKDKYDL-TQLEEKLAK*FYFEV*KK 445
E ++KE++ EE K + K+ ++ K++ L +L E AK E KK
Sbjct: 384 EEAERLEKERRAAEEAKSAIAKQAADQMKNQEQLAAELAEFTAKIALLEEAKK 436
>sp|P26043|RADI_MOUSE Radixin (ESP10)
Length = 583
Score = 39.3 bits (90), Expect = 0.006
Identities = 23/69 (33%), Positives = 38/69 (55%), Gaps = 2/69 (2%)
Frame = +2
Query: 218 QTMKDRTTNYEEEKKYLEMQLENSSTKLEWVKKEKQGLEEMKEDLMKEIEKYKDKYDLTQ 397
Q MK + + +K+ QLEN K E +KEK+ +E KE+LM+ + + +++ Q
Sbjct: 303 QQMKAQAREEKHQKQLERAQLENEKKKREIAEKEKERIEREKEELMERLRQIEEQTVKAQ 362
Query: 398 --LEEKLAK 418
LEE+ K
Sbjct: 363 KELEEQTRK 371
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 31,796,455
Number of Sequences: 369166
Number of extensions: 451277
Number of successful extensions: 5486
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4322
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5366
length of database: 68,354,980
effective HSP length: 103
effective length of database: 49,327,275
effective search space used: 3452909250
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)