Planarian EST Database


Dr_sW_017_G10

BLASTX 2.2.12 [Aug-07-2005]

Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= Dr_sW_017_G10
         (797 letters)

Database: Non-redundant SwissProt sequences 
           184,735 sequences; 68,354,980 total letters



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

sp|Q9UKR3|KLK13_HUMAN  Kallikrein 13 precursor (Kallikrein-l...   139   1e-32
sp|P80646|CTRB_GADMO  Chymotrypsin B [Contains: Chymotrypsin...   126   6e-29
sp|P47796|CTRA_GADMO  Chymotrypsin A precursor                    125   1e-28
sp|Q9JHJ7|TEST_MOUSE  Testisin precursor (Tryptase 4)             124   2e-28
sp|Q61955|NRPN_MOUSE  Neuropsin precursor (NP) (Kallikrein 8)     123   5e-28
sp|P40313|CTRL_HUMAN  Chymotrypsin-like protease CTRL-1 prec...   123   7e-28
sp|P00765|TRYP_ASTFL  Trypsin I                                   120   3e-27
sp|O88780|NRPN_RAT  Neuropsin precursor (NP) (Kallikrein-8) ...   120   3e-27
sp|P26262|KLKB1_MOUSE  Plasma kallikrein precursor (Plasma p...   120   4e-27
sp|Q9N2D1|TRYT_PIG  Tryptase precursor                            117   5e-26
>sp|Q9UKR3|KLK13_HUMAN Kallikrein 13 precursor (Kallikrein-like protein 4) (KLK-L4)
          Length = 277

 Score =  139 bits (349), Expect = 1e-32
 Identities = 85/241 (35%), Positives = 120/241 (49%), Gaps = 1/241 (0%)
 Frame = +2

Query: 20  GSQAIMHEYPQMVSIKVQGNHFCGGTLLNGNTVLTAAHCVWDMRNWNVNTFKYYQMKVYM 199
           G     H  P   ++ VQG   CGG L++   VLTAAHC+ +             +KVY+
Sbjct: 39  GYTCFPHSQPWQAALLVQGRLLCGGVLVHPKWVLTAAHCLKE------------GLKVYL 86

Query: 200 GEYDLYRMYGVEKIFQVTKTIIHPSYRHEYAYLE-GNDVALIKFDGYISKNQYDYIDYNE 376
           G++ L R+   E++ +V  +I HP YR    +L   +D+ L++    +      YI    
Sbjct: 87  GKHALGRVEAGEQVREVVHSIPHPEYRRSPTHLNHDHDIMLLELQSPVQLT--GYIQTLP 144

Query: 377 LDVNAISKPGDRCEVVGWGSMLPPGQDTSRFLQKAAINIISNSECGRIFSNVAYVRSNIC 556
           L  N    PG  C V GWG+   P  +  + LQ A I + S+ EC +++       + +C
Sbjct: 145 LSHNNRLTPGTTCRVSGWGTTTSPQVNYPKTLQCANIQLRSDEECRQVYPG-KITDNMLC 203

Query: 557 AGSGRLSTSSCRGDSGGPLFCTDGRKHHIQVGIVSYGTVPCGQPNVPSVYTRVSEVAGWI 736
           AG+      SC GDSGGPL C     +    GIVS+G  PCGQP+ P VYTRVS    WI
Sbjct: 204 AGTKEGGKDSCEGDSGGPLVC-----NRTLYGIVSWGDFPCGQPDRPGVYTRVSRYVLWI 258

Query: 737 R 739
           R
Sbjct: 259 R 259
>sp|P80646|CTRB_GADMO Chymotrypsin B [Contains: Chymotrypsin B chain A; Chymotrypsin B
           chain B]
          Length = 245

 Score =  126 bits (317), Expect = 6e-29
 Identities = 87/246 (35%), Positives = 125/246 (50%), Gaps = 3/246 (1%)
 Frame = +2

Query: 8   KIINGSQAIMHEYPQMVSIKVQ-GNHFCGGTLLNGNTVLTAAHCVWDMRNWNVNTFKYYQ 184
           +I+NG +A+ H +P  VS++   G HFCGG+L+N N V+TAAHC       NV T+    
Sbjct: 15  RIVNGEEAVPHSWPWQVSLQQSNGFHFCGGSLINENWVVTAAHC-------NVRTYH--- 64

Query: 185 MKVYMGEYDLYRMYGVEKIFQVTKTIIHPSYRHEYAYLEGNDVALIKF--DGYISKNQYD 358
            +V +GE+D      ++ I + +    HP +         ND++LIK      +  N   
Sbjct: 65  -RVIVGEHDKASDENIQ-ILKPSMVFTHPKWDSRTI---NNDISLIKLASPAVLGTNVSP 119

Query: 359 YIDYNELDVNAISKPGDRCEVVGWGSMLPPGQDTSRFLQKAAINIISNSECGRIFSNVAY 538
                  DV A   PG +C   GWG        T   LQ+AA+ ++SN EC + + N   
Sbjct: 120 VCLGESSDVFA---PGMKCVTSGWGLTRYNAPGTPNKLQQAALPLMSNEECSQTWGNNMI 176

Query: 539 VRSNICAGSGRLSTSSCRGDSGGPLFCTDGRKHHIQVGIVSYGTVPCGQPNVPSVYTRVS 718
               ICAG+     +SC GDSGGPL C       + VGIVS+G+  C     P+VY RV+
Sbjct: 177 SDVMICAGAA--GATSCMGDSGGPLVCQKDNVWTL-VGIVSWGSSRC-SVTTPAVYARVT 232

Query: 719 EVAGWI 736
           E+ GW+
Sbjct: 233 ELRGWV 238
>sp|P47796|CTRA_GADMO Chymotrypsin A precursor
          Length = 263

 Score =  125 bits (314), Expect = 1e-28
 Identities = 81/245 (33%), Positives = 129/245 (52%), Gaps = 2/245 (0%)
 Frame = +2

Query: 8   KIINGSQAIMHEYPQMVSIKVQ-GNHFCGGTLLNGNTVLTAAHCVWDMRNWNVNTFKYYQ 184
           +I+NG +A+ H +   VS++ Q G HFCGG+L+N N V+TAAHC  +++N++        
Sbjct: 33  RIVNGEEAVPHSWSWQVSLQDQTGFHFCGGSLINENWVVTAAHC--NVKNYH-------- 82

Query: 185 MKVYMGEYDLYRMYGVEKIFQVTKTIIHPSYRHEYAYLEGNDVALIKFDGYISKN-QYDY 361
            +V +GE+D        ++  V +   HP Y     +   ND+ L+K     + N +   
Sbjct: 83  -RVVLGEHDRSSNSEGVQVMTVGQVFKHPRYN---GFTINNDILLVKLATPATLNMRVSP 138

Query: 362 IDYNELDVNAISKPGDRCEVVGWGSMLPPGQDTSRFLQKAAINIISNSECGRIFSNVAYV 541
           +   E D   + + G +C   GWG       DT   LQ+AA+ +++N +C + + N    
Sbjct: 139 VCLAETD--DVFEGGMKCVTSGWGLTRYNAADTPALLQQAALPLLTNEQCKKFWGNKI-- 194

Query: 542 RSNICAGSGRLSTSSCRGDSGGPLFCTDGRKHHIQVGIVSYGTVPCGQPNVPSVYTRVSE 721
            S++   +G    SSC GDSGGPL C       + VGIVS+G+  C  P +P VY RV+E
Sbjct: 195 -SDLMICAGAAGASSCMGDSGGPLVCQKAGSWTL-VGIVSWGSGTC-TPTMPGVYARVTE 251

Query: 722 VAGWI 736
           +  W+
Sbjct: 252 LRAWV 256
>sp|Q9JHJ7|TEST_MOUSE Testisin precursor (Tryptase 4)
          Length = 324

 Score =  124 bits (312), Expect = 2e-28
 Identities = 90/259 (34%), Positives = 131/259 (50%), Gaps = 14/259 (5%)
 Frame = +2

Query: 8   KIINGSQAIMHEYPQMVSIKVQGNHFCGGTLLNGNTVLTAAHCVW---DMRNWNVNTFKY 178
           +I+ G  A +  +P   S++V GNH CG TLLN   VLTAAHC     D  +W V     
Sbjct: 54  RIVGGDDAELGRWPWQGSLRVWGNHLCGATLLNRRWVLTAAHCFQKDNDPFDWTV----- 108

Query: 179 YQMKVYMGEYDLYRMYGVEKIFQVTKTIIHPSYRHEYAYLEGNDVALIKFDGYISKNQYD 358
            Q         L+ +      +Q+    + P Y  +Y     ND+AL+K    ++ N  +
Sbjct: 109 -QFGELTSRPSLWNLQAYSNRYQIEDIFLSPKYSEQYP----NDIALLKLSSPVTYN--N 161

Query: 359 YIDYNELDVNAISKPGDR--CEVVGWGSMLPPGQDTS----RFLQKAAINIISNSECGRI 520
           +I    L +N+  K  +R  C V GWG++   G+D S      LQ+  + II+NS C  +
Sbjct: 162 FIQPICL-LNSTYKFENRTDCWVTGWGAI---GEDESLPSPNTLQEVQVAIINNSMCNHM 217

Query: 521 FSNVAYVRSNI-----CAGSGRLSTSSCRGDSGGPLFCTDGRKHHIQVGIVSYGTVPCGQ 685
           +    + R+NI     CAG+      +C GDSGGPL C D      QVG+VS+G + CG+
Sbjct: 218 YKKPDF-RTNIWGDMVCAGTPEGGKDACFGDSGGPLAC-DQDTVWYQVGVVSWG-IGCGR 274

Query: 686 PNVPSVYTRVSEVAGWIRA 742
           PN P VYT +S    WI++
Sbjct: 275 PNRPGVYTNISHHYNWIQS 293
>sp|Q61955|NRPN_MOUSE Neuropsin precursor (NP) (Kallikrein 8)
          Length = 260

 Score =  123 bits (309), Expect = 5e-28
 Identities = 79/246 (32%), Positives = 116/246 (47%)
 Frame = +2

Query: 2   GWKIINGSQAIMHEYPQMVSIKVQGNHFCGGTLLNGNTVLTAAHCVWDMRNWNVNTFKYY 181
           G KI+ G + I H  P   ++       CGG L+    VLTAAHC            K  
Sbjct: 30  GSKILEGRECIPHSQPWQAALFQGERLICGGVLVGDRWVLTAAHC------------KKQ 77

Query: 182 QMKVYMGEYDLYRMYGVEKIFQVTKTIIHPSYRHEYAYLEGNDVALIKFDGYISKNQYDY 361
           +  V +G++ L      E+  QV ++I HP Y +       +D+ LI+     S N  D 
Sbjct: 78  KYSVRLGDHSLQSRDQPEQEIQVAQSIQHPCYNNSNPEDHSHDIMLIRLQN--SANLGDK 135

Query: 362 IDYNELDVNAISKPGDRCEVVGWGSMLPPGQDTSRFLQKAAINIISNSECGRIFSNVAYV 541
           +   +L  N   K G +C + GWG++  P ++    L  A + I S ++C R +      
Sbjct: 136 VKPVQL-ANLCPKVGQKCIISGWGTVTSPQENFPNTLNCAEVKIYSQNKCERAYPG-KIT 193

Query: 542 RSNICAGSGRLSTSSCRGDSGGPLFCTDGRKHHIQVGIVSYGTVPCGQPNVPSVYTRVSE 721
              +CAGS      +C+GDSGGPL C DG       GI S+G+ PCG+P  P VYT++  
Sbjct: 194 EGMVCAGSSN-GADTCQGDSGGPLVC-DGMLQ----GITSWGSDPCGKPEKPGVYTKICR 247

Query: 722 VAGWIR 739
              WI+
Sbjct: 248 YTTWIK 253
>sp|P40313|CTRL_HUMAN Chymotrypsin-like protease CTRL-1 precursor
          Length = 264

 Score =  123 bits (308), Expect = 7e-28
 Identities = 86/246 (34%), Positives = 127/246 (51%), Gaps = 3/246 (1%)
 Frame = +2

Query: 8   KIINGSQAIMHEYPQMVSIK-VQGNHFCGGTLLNGNTVLTAAHCVWDMRNWNVNTFKYYQ 184
           +I+NG  A++  +P  VS++   G HFCGG+L++ + V+TAAHC       NV+  +++ 
Sbjct: 33  RIVNGENAVLGSWPWQVSLQDSSGFHFCGGSLISQSWVVTAAHC-------NVSPGRHF- 84

Query: 185 MKVYMGEYDLYRMYGVEKIFQVTKTIIHPSYRHEYAYLEGNDVALIKFDGYISKNQYD-- 358
             V +GEYD        ++  V++ I HPS+    +    NDV L+K     S  QY   
Sbjct: 85  --VVLGEYDRSSNAEPLQVLSVSRAITHPSWN---STTMNNDVTLLKL---ASPAQYTTR 136

Query: 359 YIDYNELDVNAISKPGDRCEVVGWGSMLPPGQDTSRFLQKAAINIISNSECGRIFSNVAY 538
                    N     G  C   GWG +   G  T   LQ+ A+ +++ ++C R +   + 
Sbjct: 137 ISPVCLASSNEALTEGLTCVTTGWGRLSGVGNVTPAHLQQVALPLVTVNQC-RQYWGSSI 195

Query: 539 VRSNICAGSGRLSTSSCRGDSGGPLFCTDGRKHHIQVGIVSYGTVPCGQPNVPSVYTRVS 718
             S ICAG      SSC+GDSGGPL C  G    + +GIVS+GT  C     P+VYTRVS
Sbjct: 196 TDSMICAGGA--GASSCQGDSGGPLVCQKGNT-WVLIGIVSWGTKNC-NVRAPAVYTRVS 251

Query: 719 EVAGWI 736
           + + WI
Sbjct: 252 KFSTWI 257
>sp|P00765|TRYP_ASTFL Trypsin I
          Length = 237

 Score =  120 bits (302), Expect = 3e-27
 Identities = 82/254 (32%), Positives = 127/254 (50%), Gaps = 8/254 (3%)
 Frame = +2

Query: 11  IINGSQAIMHEYPQMVSIKVQ----GNHFCGGTLLNGNTVLTAAHCVWDMRNWNVNTFKY 178
           I+ G+ A++ E+P  +S +        HFCG ++ N N  +TA HCV+     N +    
Sbjct: 1   IVGGTDAVLGEFPYQLSFQETFLGFSFHFCGASIYNENYAITAGHCVYGDDYENPSG--- 57

Query: 179 YQMKVYMGEYDLYRMYGVEKIFQVTKTIIHPSYRHEYAYLEGNDVALIKFDGYISKNQYD 358
             +++  GE D+    G E+   V+K I+H ++ ++   L  ND++L+K  G ++ N   
Sbjct: 58  --LQIVAGELDMSVNEGSEQTITVSKIILHENFDYD---LLDNDISLLKLSGSLTFN--- 109

Query: 359 YIDYNELDVNAISKPGDRCE----VVGWGSMLPPGQDTSRFLQKAAINIISNSECGRIFS 526
               N +   A+   G        V GWG+    G +T   LQK  + ++S++EC   + 
Sbjct: 110 ----NNVAPIALPAQGHTATGNVIVTGWGTT-SEGGNTPDVLQKVTVPLVSDAECRDDYG 164

Query: 527 NVAYVRSNICAGSGRLSTSSCRGDSGGPLFCTDGRKHHIQVGIVSYGTVPCGQPNVPSVY 706
                 S ICAG       SC+GDSGGPL  +D    ++  GIVS+G   C +P  P VY
Sbjct: 165 ADEIFDSMICAGVPEGGKDSCQGDSGGPLAASDTGSTYL-AGIVSWG-YGCARPGYPGVY 222

Query: 707 TRVSEVAGWIRANA 748
           T VS    WI+ANA
Sbjct: 223 TEVSYHVDWIKANA 236
>sp|O88780|NRPN_RAT Neuropsin precursor (NP) (Kallikrein-8) (Brain serine protease 1)
          Length = 260

 Score =  120 bits (302), Expect = 3e-27
 Identities = 77/246 (31%), Positives = 115/246 (46%)
 Frame = +2

Query: 2   GWKIINGSQAIMHEYPQMVSIKVQGNHFCGGTLLNGNTVLTAAHCVWDMRNWNVNTFKYY 181
           G KI+ G +   H  P   ++       CGG L+    VLTAAHC  D         KY 
Sbjct: 30  GSKILEGQECKPHSQPWQTALFQGERLVCGGVLVGDRWVLTAAHCKKD---------KY- 79

Query: 182 QMKVYMGEYDLYRMYGVEKIFQVTKTIIHPSYRHEYAYLEGNDVALIKFDGYISKNQYDY 361
              V +G++ L +    E+  QV ++I HP +         +D+ LI+     S N  D 
Sbjct: 80  --SVRLGDHSLQKRDEPEQEIQVARSIQHPCFNSSNPEDHSHDIMLIRLQN--SANLGDK 135

Query: 362 IDYNELDVNAISKPGDRCEVVGWGSMLPPGQDTSRFLQKAAINIISNSECGRIFSNVAYV 541
           +   EL  N   K G +C + GWG++  P ++    L  A + I S ++C R +      
Sbjct: 136 VKPIEL-ANLCPKVGQKCIISGWGTVTSPQENFPNTLNCAEVKIYSQNKCERAYPG-KIT 193

Query: 542 RSNICAGSGRLSTSSCRGDSGGPLFCTDGRKHHIQVGIVSYGTVPCGQPNVPSVYTRVSE 721
              +CAGS      +C+GDSGGPL C       +  GI ++G+ PCG+P  P VYT++  
Sbjct: 194 EGMVCAGSSN-GADTCQGDSGGPLVCNG-----VLQGITTWGSDPCGKPEKPGVYTKICR 247

Query: 722 VAGWIR 739
              WI+
Sbjct: 248 YTNWIK 253
>sp|P26262|KLKB1_MOUSE Plasma kallikrein precursor (Plasma prekallikrein) (Kininogenin)
            (Fletcher factor) [Contains: Plasma kallikrein heavy
            chain; Plasma kallikrein light chain]
          Length = 638

 Score =  120 bits (301), Expect = 4e-27
 Identities = 84/249 (33%), Positives = 125/249 (50%), Gaps = 6/249 (2%)
 Frame = +2

Query: 8    KIINGSQAIMHEYPQMVSIKVQ---GNHFCGGTLLNGNTVLTAAHCVWDMRNWNVNTFKY 178
            +I+ G+ A + E+P  VS++V+     H CGG+++    VLTAAHC   +   +V     
Sbjct: 390  RIVGGTNASLGEWPWQVSLQVKLVSQTHLCGGSIIGRQWVLTAAHCFDGIPYPDV----- 444

Query: 179  YQMKVYMGEYDLYRMYGVEKIFQVTKTIIHPSYRHEYAYLEGN-DVALIKFDGYISKNQY 355
               ++Y G   L  +       ++ + IIH     EY   EGN D+ALIK    ++  ++
Sbjct: 445  --WRIYGGILSLSEITKETPSSRIKELIIH----QEYKVSEGNYDIALIKLQTPLNYTEF 498

Query: 356  D--YIDYNELDVNAISKPGDRCEVVGWGSMLPPGQDTSRFLQKAAINIISNSECGRIFSN 529
                   ++ D N I      C V GWG     G+ T   LQKA I ++ N EC + + +
Sbjct: 499  QKPICLPSKADTNTIYT---NCWVTGWGYTKEQGE-TQNILQKATIPLVPNEECQKKYRD 554

Query: 530  VAYVRSNICAGSGRLSTSSCRGDSGGPLFCTDGRKHHIQVGIVSYGTVPCGQPNVPSVYT 709
                +  ICAG     T +C+GDSGGPL C    +  + VGI S+G   CG+ + P VYT
Sbjct: 555  YVINKQMICAGYKEGGTDACKGDSGGPLVCKHSGRWQL-VGITSWGE-GCGRKDQPGVYT 612

Query: 710  RVSEVAGWI 736
            +VSE   WI
Sbjct: 613  KVSEYMDWI 621
>sp|Q9N2D1|TRYT_PIG Tryptase precursor
          Length = 275

 Score =  117 bits (292), Expect = 5e-26
 Identities = 87/260 (33%), Positives = 133/260 (51%), Gaps = 18/260 (6%)
 Frame = +2

Query: 11  IINGSQAIMHEYPQMVSIKVQGN---HFCGGTLLNGNTVLTAAHCVWDMRNWNVNTFKYY 181
           I+ G +A  H++P  VS++       HFCGG+L++   VLTAAHC      +        
Sbjct: 31  IVGGKEAPGHKWPWQVSLRCLDQYWKHFCGGSLIHPQWVLTAAHC------FGPEKADPL 84

Query: 182 QMKVYMGEYDLYRMYGVEKIFQVTKTIIHPSYRHEYAYLEGNDVALIKFDGYISKNQYDY 361
            ++V +GE  LY     +++  V++ I+HP+Y   Y  + G D+AL++ +  +  N   +
Sbjct: 85  YIRVQLGEQHLYYQ---DRLLLVSRIIVHPNY---YDEVNGADIALLELEDPV--NLSSH 136

Query: 362 IDYNELDVNAISKP-GDRCEVVGWGSM-----LPPGQDTSRFLQKAAINIISNSECGRIF 523
           +    L   + + P G RC V GWG +     LPP       L++  + I+ NSEC   +
Sbjct: 137 VQPVTLPPASETFPKGTRCWVTGWGDVHSGWPLPPPYP----LKQVRVPIVENSECDMQY 192

Query: 524 -------SNVAYVRSN-ICAGSGRLSTSSCRGDSGGPLFC-TDGRKHHIQVGIVSYGTVP 676
                   N+  VR + +CAGS      SC+GDSGGPL C  +G    +Q G+VS+G   
Sbjct: 193 HLGLSTGDNIPIVRDDMLCAGSE--GHDSCQGDSGGPLVCRVNGT--WLQAGVVSWGE-G 247

Query: 677 CGQPNVPSVYTRVSEVAGWI 736
           C  PN P +YTRV+    WI
Sbjct: 248 CALPNRPGIYTRVTHYLDWI 267
  Database: Non-redundant SwissProt sequences
    Posted date:  Dec 6, 2005  7:40 AM
  Number of letters in database: 68,354,980
  Number of sequences in database:  184,735
  
  Database: swissprot.01
    Posted date:  Dec 6, 2005  8:18 AM
  Number of letters in database: 66,202,850
  Number of sequences in database:  184,431
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 98,083,737
Number of Sequences: 369166
Number of extensions: 2141534
Number of successful extensions: 6941
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 5612
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5843
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 7522142940
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)