Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_017_F13
(954 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q60HE2|ODO1_MACFA 2-oxoglutarate dehydrogenase E1 compon... 388 e-107
sp|Q60597|ODO1_MOUSE 2-oxoglutarate dehydrogenase E1 compon... 387 e-107
sp|Q5RCB8|ODO1_PONPY 2-oxoglutarate dehydrogenase E1 compon... 386 e-107
sp|Q02218|ODO1_HUMAN 2-oxoglutarate dehydrogenase E1 compon... 375 e-103
sp|P20967|ODO1_YEAST 2-oxoglutarate dehydrogenase E1 compon... 281 2e-75
sp|Q9ZDY3|ODO1_RICPR 2-oxoglutarate dehydrogenase E1 compon... 258 1e-68
sp|Q92J42|ODO1_RICCN 2-oxoglutarate dehydrogenase E1 compon... 254 2e-67
sp|Q59106|ODO1_RALEU 2-oxoglutarate dehydrogenase E1 compon... 253 6e-67
sp|P51056|ODO1_COXBU 2-oxoglutarate dehydrogenase E1 compon... 249 8e-66
sp|P45303|ODO1_HAEIN 2-oxoglutarate dehydrogenase E1 compon... 249 1e-65
>sp|Q60HE2|ODO1_MACFA 2-oxoglutarate dehydrogenase E1 component, mitochondrial precursor
(Alpha-ketoglutarate dehydrogenase)
Length = 1023
Score = 388 bits (997), Expect = e-107
Identities = 187/314 (59%), Positives = 233/314 (74%), Gaps = 1/314 (0%)
Frame = +1
Query: 1 YAGQAEFSVSNSSLSEYAVLGFELGFSQTDPNALVIWEAQFGDFNNTAQCIIDQFIASGQ 180
+ QA ++V NSSLSEY VLGFELGF+ PNALV+WEAQFGDF+NTAQCIIDQFI GQ
Sbjct: 707 WPNQAPYTVCNSSLSEYGVLGFELGFAMASPNALVLWEAQFGDFHNTAQCIIDQFICPGQ 766
Query: 181 SKWVRQSGLVMLLPHGYEGMGPEHSSGRLERFLQMSNDDQDYIPPFGE-HFEAQQLHDIN 357
+KWVRQ+G+V+LLPHG EGMGPEHSS R ERFLQM NDD D +P E +F+ QLHD N
Sbjct: 767 AKWVRQNGIVLLLPHGMEGMGPEHSSARPERFLQMCNDDPDVLPDLKEANFDINQLHDCN 826
Query: 358 WFVVNCTTPANMFHVLRRQVLLSFRKPLIAMTPKSLLRLPEAKSSFDEMIGDTKFKRIIS 537
W VVNC+TP N FHVLRRQ+LL FRKPLI TPKSLLR PEA+SSFDEM+ T F+R+I
Sbjct: 827 WVVVNCSTPGNFFHVLRRQILLPFRKPLIIFTPKSLLRHPEARSSFDEMLPGTHFQRVIP 886
Query: 538 ESGIANENPEKVEKVILCSGKVYYELMKERERRSLQDRIAIVRLEQISPFPYDLLFEELT 717
E G A +NPE V++++ C+GKVYY+L +ER+ R + ++AI R+EQ+SPFP+DLL +E+
Sbjct: 887 EDGPAAQNPENVKRLLFCTGKVYYDLTRERKARDMVGQVAITRIEQLSPFPFDLLLKEVQ 946
Query: 718 KFSEAGVQWVQEEHKNMGAWFYVEPRVNNLIKVKLPNHRKPKISYVGRPPSAAAAAGNKF 897
K+ A + W QEEHKN G + YV+PR+ I R + Y GR P+AA A GNK
Sbjct: 947 KYPNAELAWCQEEHKNQGYYDYVKPRLRTTIS------RAKPVWYAGRDPAAAPATGNKK 1000
Query: 898 IHLMEISQFMRQLF 939
HL E+ + + F
Sbjct: 1001 THLTELQRLLDTAF 1014
>sp|Q60597|ODO1_MOUSE 2-oxoglutarate dehydrogenase E1 component, mitochondrial precursor
(Alpha-ketoglutarate dehydrogenase)
Length = 1019
Score = 387 bits (995), Expect = e-107
Identities = 185/314 (58%), Positives = 235/314 (74%), Gaps = 1/314 (0%)
Frame = +1
Query: 1 YAGQAEFSVSNSSLSEYAVLGFELGFSQTDPNALVIWEAQFGDFNNTAQCIIDQFIASGQ 180
+ QA ++V NSSLSEY VLGFELGF+ PNALV+WEAQFGDFNN AQCIIDQFI GQ
Sbjct: 703 WPNQAPYTVCNSSLSEYGVLGFELGFAMASPNALVLWEAQFGDFNNMAQCIIDQFICPGQ 762
Query: 181 SKWVRQSGLVMLLPHGYEGMGPEHSSGRLERFLQMSNDDQDYIPPFGE-HFEAQQLHDIN 357
+KWVRQ+G+V+LLPHG EGMGPEHSS R ERFLQM NDD D +P E +F+ QL+D N
Sbjct: 763 AKWVRQNGIVLLLPHGMEGMGPEHSSARPERFLQMCNDDPDVLPDLQEENFDINQLYDCN 822
Query: 358 WFVVNCTTPANMFHVLRRQVLLSFRKPLIAMTPKSLLRLPEAKSSFDEMIGDTKFKRIIS 537
W VVNC+TP N FHVLRRQ+LL FRKPLI TPKSLLR PEA++SFDEM+ T F+R+I
Sbjct: 823 WIVVNCSTPGNFFHVLRRQILLPFRKPLIVFTPKSLLRHPEARTSFDEMLPGTHFQRVIP 882
Query: 538 ESGIANENPEKVEKVILCSGKVYYELMKERERRSLQDRIAIVRLEQISPFPYDLLFEELT 717
E+G A ++P KV++++ C+GKVYY+L +ER+ R++++ +AI R+EQ+SPFP+DLL +E
Sbjct: 883 ENGPAAQDPHKVKRLLFCTGKVYYDLTRERKARNMEEEVAITRIEQLSPFPFDLLLKEAQ 942
Query: 718 KFSEAGVQWVQEEHKNMGAWFYVEPRVNNLIKVKLPNHRKPKISYVGRPPSAAAAAGNKF 897
K+ A + W QEEHKN G + YV+PR+ I R + Y GR P+AA A GNK
Sbjct: 943 KYPNAELAWCQEEHKNQGYYDYVKPRLRTTI------DRAKPVWYAGRDPAAAPATGNKK 996
Query: 898 IHLMEISQFMRQLF 939
HL E+ +F+ F
Sbjct: 997 THLTELQRFLDTAF 1010
>sp|Q5RCB8|ODO1_PONPY 2-oxoglutarate dehydrogenase E1 component, mitochondrial precursor
(Alpha-ketoglutarate dehydrogenase)
Length = 1023
Score = 386 bits (991), Expect = e-107
Identities = 186/314 (59%), Positives = 233/314 (74%), Gaps = 1/314 (0%)
Frame = +1
Query: 1 YAGQAEFSVSNSSLSEYAVLGFELGFSQTDPNALVIWEAQFGDFNNTAQCIIDQFIASGQ 180
+ QA ++V NSSLSEY VLGFELGF+ PNALV+WEAQFGDF+NTAQCIIDQFI GQ
Sbjct: 707 WPNQAPYTVCNSSLSEYGVLGFELGFAMASPNALVLWEAQFGDFHNTAQCIIDQFICPGQ 766
Query: 181 SKWVRQSGLVMLLPHGYEGMGPEHSSGRLERFLQMSNDDQDYIPPFGE-HFEAQQLHDIN 357
+KWVRQ+G+V+LLPHG EGMGPEHSS R ERFLQM NDD D +P E +F+ QL+D N
Sbjct: 767 AKWVRQNGIVLLLPHGMEGMGPEHSSARPERFLQMCNDDPDVLPDLKEANFDINQLYDCN 826
Query: 358 WFVVNCTTPANMFHVLRRQVLLSFRKPLIAMTPKSLLRLPEAKSSFDEMIGDTKFKRIIS 537
W VVNC+TP N FHVLRRQ+LL FRKPLI TPKSLLR PEA+SSFDEM+ T F+R+I
Sbjct: 827 WVVVNCSTPGNFFHVLRRQILLPFRKPLIIFTPKSLLRHPEARSSFDEMLPGTHFQRVIP 886
Query: 538 ESGIANENPEKVEKVILCSGKVYYELMKERERRSLQDRIAIVRLEQISPFPYDLLFEELT 717
E G A +NPE V++++ C+GKVYY+L +ER+ R + ++AI R+EQ+SPFP+DLL +E+
Sbjct: 887 EDGPAAQNPENVKRLLFCTGKVYYDLTRERKARDMVGQVAITRIEQLSPFPFDLLLKEVQ 946
Query: 718 KFSEAGVQWVQEEHKNMGAWFYVEPRVNNLIKVKLPNHRKPKISYVGRPPSAAAAAGNKF 897
K+ A + W QEEHKN G + YV+PR+ I R + Y GR P+AA A GNK
Sbjct: 947 KYPSAELAWCQEEHKNQGYYDYVKPRLRTTIS------RAKPVWYAGRDPAAAPATGNKK 1000
Query: 898 IHLMEISQFMRQLF 939
HL E+ + + F
Sbjct: 1001 THLTELQRLLDTAF 1014
>sp|Q02218|ODO1_HUMAN 2-oxoglutarate dehydrogenase E1 component, mitochondrial precursor
(Alpha-ketoglutarate dehydrogenase)
Length = 1002
Score = 375 bits (962), Expect = e-103
Identities = 181/302 (59%), Positives = 224/302 (74%), Gaps = 1/302 (0%)
Frame = +1
Query: 1 YAGQAEFSVSNSSLSEYAVLGFELGFSQTDPNALVIWEAQFGDFNNTAQCIIDQFIASGQ 180
+ QA ++V NSSLSEY VLGFE G PNALV+WEAQFGDF+NTAQCIIDQFI GQ
Sbjct: 707 WPNQAPYTVCNSSLSEYGVLGFEAGLRMASPNALVLWEAQFGDFHNTAQCIIDQFICPGQ 766
Query: 181 SKWVRQSGLVMLLPHGYEGMGPEHSSGRLERFLQMSNDDQDYIPPFGE-HFEAQQLHDIN 357
+KWVRQ+G+V+LLPHG EGMGPEHSS R ERFLQM NDD D +P E +F+ QL+D N
Sbjct: 767 AKWVRQNGIVLLLPHGMEGMGPEHSSARPERFLQMCNDDPDVLPDLKEANFDINQLYDCN 826
Query: 358 WFVVNCTTPANMFHVLRRQVLLSFRKPLIAMTPKSLLRLPEAKSSFDEMIGDTKFKRIIS 537
W VVNC+TP N FHVLRRQ+LL FRKPLI TPKSLLR PEA+SSFDEM+ T F+R+I
Sbjct: 827 WVVVNCSTPGNFFHVLRRQILLPFRKPLIIFTPKSLLRHPEARSSFDEMLPGTHFQRVIP 886
Query: 538 ESGIANENPEKVEKVILCSGKVYYELMKERERRSLQDRIAIVRLEQISPFPYDLLFEELT 717
E G A +NPE V++++ C+GKVYY+L +ER+ R + ++AI R+EQ+SPFP+DLL +E+
Sbjct: 887 EDGPAAQNPENVKRLLFCTGKVYYDLTRERKARDMVGQVAITRIEQLSPFPFDLLLKEVQ 946
Query: 718 KFSEAGVQWVQEEHKNMGAWFYVEPRVNNLIKVKLPNHRKPKISYVGRPPSAAAAAGNKF 897
K+ A + W QEEHKN G + YV+PR+ I R + Y GR P+AA A GNK
Sbjct: 947 KYPNAELAWCQEEHKNQGYYDYVKPRLRTTIS------RAKPVWYAGRNPAAAPATGNKK 1000
Query: 898 IH 903
H
Sbjct: 1001 TH 1002
>sp|P20967|ODO1_YEAST 2-oxoglutarate dehydrogenase E1 component, mitochondrial precursor
(Alpha-ketoglutarate dehydrogenase)
Length = 1014
Score = 281 bits (719), Expect = 2e-75
Identities = 155/315 (49%), Positives = 209/315 (66%), Gaps = 4/315 (1%)
Frame = +1
Query: 10 QAEFSVSNSSLSEYAVLGFELGFSQTDPNALVIWEAQFGDFNNTAQCIIDQFIASGQSKW 189
+A+F+++NSSLSEY V+GFE G+S T P+ LV+WEAQFGDF NTAQ IIDQFIA G+ KW
Sbjct: 704 KADFTIANSSLSEYGVMGFEYGYSLTSPDYLVMWEAQFGDFANTAQVIIDQFIAGGEQKW 763
Query: 190 VRQSGLVMLLPHGYEGMGPEHSSGRLERFLQMSNDDQDYIPPFGEHFEAQQLHDINWFVV 369
++SGLV+ LPHGY+G GPEHSSGRLERFLQ++N+D Y P E +Q D N+ VV
Sbjct: 764 KQRSGLVLSLPHGYDGQGPEHSSGRLERFLQLANEDPRYFP--SEEKLQRQHQDCNFQVV 821
Query: 370 NCTTPANMFHVLRRQVLLSFRKPLIAMTPKSLLRLPEAKSSFDEMIGDTKFKRIIS--ES 543
TTPAN+FH+LRRQ FRKPL K LLR P A+SS E + F+ II E
Sbjct: 822 YPTTPANLFHILRRQQHRQFRKPLALFFSKQLLRHPLARSSLSEFT-EGGFQWIIEDIEH 880
Query: 544 GIANENPEKVEKVILCSGKVYYELMKERERRSLQDR-IAIVRLEQISPFPYDLLFEELTK 720
G + E+ ++++L SG+VY L K RE SL D+ A +++EQ+ PFP+ L + L
Sbjct: 881 GKSIGTKEETKRLVLLSGQVYTALHKRRE--SLGDKTTAFLKIEQLHPFPFAQLRDSLNS 938
Query: 721 FSE-AGVQWVQEEHKNMGAWFYVEPRVNNLIKVKLPNHRKPKISYVGRPPSAAAAAGNKF 897
+ + W QEE NMG+W Y EPR++ +K + ++ K+ Y GR PS A AAG+K
Sbjct: 939 YPNLEEIVWCQEEPLNMGSWAYTEPRLHTTLK-ETDKYKDFKVRYCGRNPSGAVAAGSKS 997
Query: 898 IHLMEISQFMRQLFR 942
+HL E F++ +F+
Sbjct: 998 LHLAEEDAFLKDVFQ 1012
>sp|Q9ZDY3|ODO1_RICPR 2-oxoglutarate dehydrogenase E1 component (Alpha-ketoglutarate
dehydrogenase)
Length = 936
Score = 258 bits (660), Expect = 1e-68
Identities = 145/299 (48%), Positives = 189/299 (63%), Gaps = 1/299 (0%)
Frame = +1
Query: 10 QAEFSVSNSSLSEYAVLGFELGFSQTDPNALVIWEAQFGDFNNTAQCIIDQFIASGQSKW 189
QA++ V+NS+LSEYA LGFE G+S +P LV+WEAQFGDF N AQ I DQFI+S +KW
Sbjct: 643 QAKYEVANSNLSEYAALGFEYGYSLANPKNLVLWEAQFGDFANGAQIIFDQFISSSATKW 702
Query: 190 VRQSGLVMLLPHGYEGMGPEHSSGRLERFLQMSNDDQDYIPPFGEHFEAQQLHDINWFVV 369
+R SGLV+LLPH +EG GPEHSS RLERFLQ++ ++ N ++
Sbjct: 703 LRMSGLVVLLPHAFEGQGPEHSSARLERFLQLAAEE-------------------NMYIT 743
Query: 370 NCTTPANMFHVLRRQVLLSFRKPLIAMTPKSLLRLPEAKSSFDEMIGDTKFKRIISESGI 549
TTPA++FH+LRRQ+L S RKPLI M+PKSLLR A S DE+ +T F I+ E +
Sbjct: 744 YPTTPASIFHLLRRQILESTRKPLIVMSPKSLLRHKYAVSKLDELGENTTFIPILDE--V 801
Query: 550 ANENPEKVEKVILCSGKVYYELMKERERRSLQDRIAIVRLEQISPFPYDLLFEELTKFSE 729
+ V KVILCSGKVYY+L R S I I+RLEQ+ PF L+ L K+++
Sbjct: 802 TKIDTNNVTKVILCSGKVYYDLFAMRTNNS---NIVIIRLEQLYPFEKKLVASLLKKYNK 858
Query: 730 A-GVQWVQEEHKNMGAWFYVEPRVNNLIKVKLPNHRKPKISYVGRPPSAAAAAGNKFIH 903
A W QEE KNMGAW Y+ +N+ +K N+ + YVGR SA+ A G+ +H
Sbjct: 859 AQAFIWCQEEPKNMGAWHYIATHLNDALKEAEINN---EFKYVGREESASPAVGSLQVH 914
>sp|Q92J42|ODO1_RICCN 2-oxoglutarate dehydrogenase E1 component (Alpha-ketoglutarate
dehydrogenase)
Length = 928
Score = 254 bits (649), Expect = 2e-67
Identities = 143/308 (46%), Positives = 191/308 (62%), Gaps = 1/308 (0%)
Frame = +1
Query: 10 QAEFSVSNSSLSEYAVLGFELGFSQTDPNALVIWEAQFGDFNNTAQCIIDQFIASGQSKW 189
QA++ V++S+LSEYAVLGFE G+S +P LV+WEAQFGDF N AQ I DQFI+S ++KW
Sbjct: 643 QAKYEVADSNLSEYAVLGFEYGYSLANPKNLVLWEAQFGDFANGAQIIFDQFISSSETKW 702
Query: 190 VRQSGLVMLLPHGYEGMGPEHSSGRLERFLQMSNDDQDYIPPFGEHFEAQQLHDINWFVV 369
+R SGLV+LLPH +EG GPEHSS RLERFLQ++ ++ N +V
Sbjct: 703 LRMSGLVVLLPHAFEGQGPEHSSARLERFLQLAAEN-------------------NMYVT 743
Query: 370 NCTTPANMFHVLRRQVLLSFRKPLIAMTPKSLLRLPEAKSSFDEMIGDTKFKRIISESGI 549
TTPA++FH+LRRQ+L RKPLI M+PKSLLR A S DE+ +T F ++ E +
Sbjct: 744 YPTTPASIFHLLRRQILDDTRKPLIVMSPKSLLRHKYAVSKLDELGENTTFLPVLDE--V 801
Query: 550 ANENPEKVEKVILCSGKVYYELMKERERRSLQDRIAIVRLEQISPFPYDLLFEELTKFSE 729
+ + KVILCSGKVYY+L E R IAI+RLEQ+ PF L+ L K++
Sbjct: 802 TKVDTNNITKVILCSGKVYYDLF---EMRGNNSNIAIIRLEQLYPFEKKLVASLLKKYNR 858
Query: 730 A-GVQWVQEEHKNMGAWFYVEPRVNNLIKVKLPNHRKPKISYVGRPPSAAAAAGNKFIHL 906
W QEE KNMG W Y+ +N+ +K K + YVGR SA+ A G+ +H
Sbjct: 859 TQEFIWCQEEPKNMGTWCYIVSHLNDALK---EAGIKNEFKYVGREESASPAVGSLQVHN 915
Query: 907 MEISQFMR 930
+ + +R
Sbjct: 916 KQQEKLLR 923
>sp|Q59106|ODO1_RALEU 2-oxoglutarate dehydrogenase E1 component (Alpha-ketoglutarate
dehydrogenase)
Length = 950
Score = 253 bits (646), Expect = 6e-67
Identities = 142/294 (48%), Positives = 187/294 (63%), Gaps = 1/294 (0%)
Frame = +1
Query: 10 QAEFSVSNSSLSEYAVLGFELGFSQTDPNALVIWEAQFGDFNNTAQCIIDQFIASGQSKW 189
QA F+V +S LSE AVLGFE G+S +PNALVIWEAQFGDF N AQ +IDQFI+SG+ KW
Sbjct: 659 QAPFTVIDSVLSEEAVLGFEYGYSAAEPNALVIWEAQFGDFVNGAQVVIDQFISSGEVKW 718
Query: 190 VRQSGLVMLLPHGYEGMGPEHSSGRLERFLQMSNDDQDYIPPFGEHFEAQQLHDINWFVV 369
R SGL ++LPHGYEG GPEHSS R+ERFLQ+ D N V
Sbjct: 719 GRASGLTLMLPHGYEGQGPEHSSARIERFLQLCADH-------------------NMQVC 759
Query: 370 NCTTPANMFHVLRRQVLLSFRKPLIAMTPKSLLRLPEAKSSFDEMIGDTKFKRIISESGI 549
TTPA +FH+LRRQ++ FRKPL+ MTPKSLLR +A S + + F+ +I +
Sbjct: 760 QPTTPAQIFHLLRRQMIRLFRKPLVIMTPKSLLRNKDAVSPLSD-LAKGHFETVIPDH-- 816
Query: 550 ANENPEKVEKVILCSGKVYYELMKERERRSLQDRIAIVRLEQISPFPYDLLFEELTKFSE 729
N KV++VI+CSGKVYY+L+ R+ R D A++RLEQ+ PFP+ + EL K+
Sbjct: 817 EELNASKVKRVIMCSGKVYYDLVNTRKEREAND-TAVIRLEQLYPFPHKAVAAELKKYPN 875
Query: 730 A-GVQWVQEEHKNMGAWFYVEPRVNNLIKVKLPNHRKPKISYVGRPPSAAAAAG 888
A + W Q+E +N GAWF+V+ + I + + + K+ Y GRP SA+ A G
Sbjct: 876 ATEIVWCQDEPQNQGAWFFVQ----HYIMENMTDGQ--KLGYAGRPASASPAVG 923
>sp|P51056|ODO1_COXBU 2-oxoglutarate dehydrogenase E1 component (Alpha-ketoglutarate
dehydrogenase)
Length = 934
Score = 249 bits (636), Expect = 8e-66
Identities = 147/310 (47%), Positives = 189/310 (60%), Gaps = 2/310 (0%)
Frame = +1
Query: 10 QAEFSVSNSSLSEYAVLGFELGFSQTDPNALVIWEAQFGDFNNTAQCIIDQFIASGQSKW 189
QA + +S L E LGFE G+S DPN+LVIWEAQFGDF N AQ I+DQFI+SG KW
Sbjct: 649 QAAPHIYDSLLCEAGALGFEYGYSTADPNSLVIWEAQFGDFANVAQVIVDQFISSGWQKW 708
Query: 190 VRQSGLVMLLPHGYEGMGPEHSSGRLERFLQMSNDDQDYIPPFGEHFEAQQLHDINWFVV 369
R SG+V+ LPHGYEG GPEHSS RLER+LQ+ + N V
Sbjct: 709 NRLSGIVLFLPHGYEGKGPEHSSARLERYLQLCAQN-------------------NMQVC 749
Query: 370 NCTTPANMFHVLRRQVLLSFRKPLIAMTPKSLLRLPEAKSSFDEMIGDTKFKRIISESGI 549
TTP+ +FH+LRRQVL +RKPL+ +TPKS+LR A SS ++ + + K +I E I
Sbjct: 750 APTTPSQIFHLLRRQVLRPYRKPLVVLTPKSVLRNKLAVSSLED-LARGQLKLLIPE--I 806
Query: 550 ANENPEKVEKVILCSGKVYYELM-KERERRSLQDRIAIVRLEQISPFPYDLLFEELTKFS 726
+P+K+ +VILCSGKVYY+L+ K RE + + IA++R+EQ+ PFPYD L EL K+
Sbjct: 807 EKHDPKKITRVILCSGKVYYDLLAKRREHKGKLNHIAMIRIEQLYPFPYDELKAELEKYP 866
Query: 727 EA-GVQWVQEEHKNMGAWFYVEPRVNNLIKVKLPNHRKPKISYVGRPPSAAAAAGNKFIH 903
A V W QEE KN GAWF R LIK + + YVGR AA AAG ++
Sbjct: 867 NAKQVIWCQEEPKNQGAWFCTRHR---LIKCMRDDQ---TLEYVGRSAFAAPAAGYSALY 920
Query: 904 LMEISQFMRQ 933
+ Q + Q
Sbjct: 921 VKLQEQLVNQ 930
>sp|P45303|ODO1_HAEIN 2-oxoglutarate dehydrogenase E1 component (Alpha-ketoglutarate
dehydrogenase)
Length = 935
Score = 249 bits (635), Expect = 1e-65
Identities = 139/310 (44%), Positives = 191/310 (61%), Gaps = 1/310 (0%)
Frame = +1
Query: 1 YAGQAEFSVSNSSLSEYAVLGFELGFSQTDPNALVIWEAQFGDFNNTAQCIIDQFIASGQ 180
+A Q F V +S LSE +VL FE G++ TDP L IWEAQFGDF N AQ +IDQFI+SG+
Sbjct: 649 HANQGRFEVWDSVLSEESVLAFEYGYATTDPKTLTIWEAQFGDFANGAQIVIDQFISSGE 708
Query: 181 SKWVRQSGLVMLLPHGYEGMGPEHSSGRLERFLQMSNDDQDYIPPFGEHFEAQQLHDINW 360
KW R GLVMLLPHGYEG GPEHSS RLER+LQ+ + N
Sbjct: 709 QKWGRMCGLVMLLPHGYEGQGPEHSSARLERYLQLCAEQ-------------------NM 749
Query: 361 FVVNCTTPANMFHVLRRQVLLSFRKPLIAMTPKSLLRLPEAKSSFDEMIGDTKFKRIISE 540
V +TPA ++H+LRRQ L R+PLIA++PKSLLR P A SS DE+I T F+ +I E
Sbjct: 750 QVCVPSTPAQVYHMLRRQSLRKMRRPLIAISPKSLLRHPLAVSSLDELINGT-FQTVIGE 808
Query: 541 SGIANENPEKVEKVILCSGKVYYELMKERERRSLQDRIAIVRLEQISPFPYDLLFEELTK 720
I +P+ V++V++CSGKVYY+L+++R + +D +AI+R+EQ+ PFP++ + + L
Sbjct: 809 --IDELDPKDVKRVVMCSGKVYYDLLEQRRANNQKD-VAIIRIEQLYPFPHEDVKKALEP 865
Query: 721 FSE-AGVQWVQEEHKNMGAWFYVEPRVNNLIKVKLPNHRKPKISYVGRPPSAAAAAGNKF 897
++ W QEE N GAW+ + + I + K+ Y GRP SA+ A G
Sbjct: 866 YAHVTDYVWCQEEPLNQGAWYCSKHNFESAIPESV------KLKYAGRPASASPAVGYMS 919
Query: 898 IHLMEISQFM 927
+H + Q +
Sbjct: 920 LHTKQQKQLV 929
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 115,141,292
Number of Sequences: 369166
Number of extensions: 2425974
Number of successful extensions: 6260
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 5986
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6199
length of database: 68,354,980
effective HSP length: 111
effective length of database: 47,849,395
effective search space used: 9856975370
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)