Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_017_F12
(630 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|O15143|ARC1B_HUMAN Actin-related protein 2/3 complex sub... 114 2e-25
sp|O88656|ARC1B_RAT Actin-related protein 2/3 complex subun... 114 3e-25
sp|Q9R0Q6|ARC1A_MOUSE Actin-related protein 2/3 complex sub... 111 2e-24
sp|Q92747|ARC1A_HUMAN Actin-related protein 2/3 complex sub... 110 4e-24
sp|Q9WV32|ARC1B_MOUSE Actin-related protein 2/3 complex sub... 109 5e-24
sp|Q99PD4|ARC1A_RAT Actin-related protein 2/3 complex subun... 109 7e-24
sp|P78774|ARPC1_SCHPO Probable ARP2/3 complex 41 kDa subuni... 80 6e-15
sp|P38328|ARPC1_YEAST Probable ARP2/3 complex 41 kDa subuni... 59 1e-08
sp|Q91VU6|WDR23_MOUSE WD-repeat protein 23 34 0.27
sp|Q8TEB1|WDR23_HUMAN WD-repeat protein 23 34 0.27
>sp|O15143|ARC1B_HUMAN Actin-related protein 2/3 complex subunit 1B (ARP2/3 complex 41 kDa
subunit) (p41-ARC)
Length = 372
Score = 114 bits (286), Expect = 2e-25
Identities = 55/179 (30%), Positives = 100/179 (55%), Gaps = 5/179 (2%)
Frame = +3
Query: 3 SEGGLGWIHSIAFSNDGNKLIWSTHSSTICVATVSGSQQPPSVKMILMDNLPFLTLVWAA 182
S GW+H + FS G+++ W +H ST+C+A + + +V + + LP L L +
Sbjct: 198 SSSSCGWVHGVCFSASGSRVAWVSHDSTVCLAD---ADKKMAVATLASETLPLLALTFIT 254
Query: 183 PNTVIGAGHDCVP--FTISTDKDQLKLGTSLDSKEELNTNATLSAKDRFRQIDRIATADS 356
N+++ AGHDC P FT L G LD ++ ++ L+A++RF+ +D+ A+++
Sbjct: 255 DNSLVAAGHDCFPVLFTYDAAAGMLSFGGRLDVPKQ-SSQRGLTARERFQNLDKKASSEG 313
Query: 357 NDSI---INSKHKNAINEIRIMKGSNGSAQVLSTIGRDGQLILWDLKTLSQKMSDLKIQ 524
+ ++S HKN++++I ++ G T G DG + +WD+K+L + DLKI+
Sbjct: 314 GTAAGAGLDSLHKNSVSQISVLSGGKAKCSQFCTTGMDGGMSIWDVKSLESALKDLKIK 372
>sp|O88656|ARC1B_RAT Actin-related protein 2/3 complex subunit 1B (ARP2/3 complex 41 kDa
subunit) (p41-ARC)
Length = 372
Score = 114 bits (284), Expect = 3e-25
Identities = 54/179 (30%), Positives = 100/179 (55%), Gaps = 5/179 (2%)
Frame = +3
Query: 3 SEGGLGWIHSIAFSNDGNKLIWSTHSSTICVATVSGSQQPPSVKMILMDNLPFLTLVWAA 182
S GW+H + FS G+++ W +H ST+C+ +++ +V + + LP L + +
Sbjct: 198 SSSSCGWVHGVCFSAGGSRVAWVSHDSTVCLVD---AEKKMAVATLASETLPLLAITFIT 254
Query: 183 PNTVIGAGHDCVP--FTISTDKDQLKLGTSLDSKEELNTNATLSAKDRFRQIDRIATADS 356
N+++ AGHDC P FT L G LD ++ N+ L+A++RF+ +D+ A+++
Sbjct: 255 ENSLVAAGHDCFPVLFTYDNAAGTLSFGGRLDVPKQ-NSQRGLTARERFQNLDKKASSEG 313
Query: 357 NDSI---INSKHKNAINEIRIMKGSNGSAQVLSTIGRDGQLILWDLKTLSQKMSDLKIQ 524
+ ++S HKN++++I ++ G T G DG + +WD+K+L + DLKI+
Sbjct: 314 GAATGAGLDSLHKNSVSQISVLSGGKAKCSQFCTTGMDGGMSIWDVKSLESALKDLKIR 372
>sp|Q9R0Q6|ARC1A_MOUSE Actin-related protein 2/3 complex subunit 1A (SOP2-like protein)
(Sid 329)
Length = 370
Score = 111 bits (277), Expect = 2e-24
Identities = 58/170 (34%), Positives = 96/170 (56%), Gaps = 2/170 (1%)
Frame = +3
Query: 18 GWIHSIAFSNDGNKLIWSTHSSTICVATVSGSQQPPSVKMILMDNLPFLTLVWAAPNTVI 197
GW+H ++FS GN+L W +H ST+ VA S S Q V + + LP L++ + + N+V+
Sbjct: 205 GWVHGVSFSASGNRLAWVSHDSTVSVADASKSVQ---VSTLRTEFLPLLSVSFVSENSVV 261
Query: 198 GAGHDCVPFTIS-TDKDQLKLGTSLD-SKEELNTNATLSAKDRFRQIDRIATADSNDSII 371
AGHDC P + D+ L + LD K+ + N +SA +RFR +D+ AT + ++ +
Sbjct: 262 AAGHDCCPMLFNYDDRGCLTFVSKLDVPKQSIQRN--MSAMERFRNMDKRATTEDRNTAL 319
Query: 372 NSKHKNAINEIRIMKGSNGSAQVLSTIGRDGQLILWDLKTLSQKMSDLKI 521
+ H+N+I ++ I + + T G DG + +WD KTL + L+I
Sbjct: 320 ETLHQNSITQVSIYEVDKQDCRKFCTTGIDGAMTIWDFKTLESSIQGLRI 369
>sp|Q92747|ARC1A_HUMAN Actin-related protein 2/3 complex subunit 1A (SOP2-like protein)
Length = 370
Score = 110 bits (274), Expect = 4e-24
Identities = 58/170 (34%), Positives = 97/170 (57%), Gaps = 2/170 (1%)
Frame = +3
Query: 18 GWIHSIAFSNDGNKLIWSTHSSTICVATVSGSQQPPSVKMILMDNLPFLTLVWAAPNTVI 197
GW+H ++FS G++L W +H ST+ VA S S Q ++K + LP L++ + + N+V+
Sbjct: 205 GWVHGVSFSASGSRLAWVSHDSTVSVADASKSVQVSTLKT---EFLPLLSVSFVSENSVV 261
Query: 198 GAGHDCVPFT-ISTDKDQLKLGTSLD-SKEELNTNATLSAKDRFRQIDRIATADSNDSII 371
AGHDC P I D+ L + LD K+ + N +SA +RFR +D+ AT + ++ +
Sbjct: 262 AAGHDCCPMLFIYDDRGCLTFVSKLDIPKQSIQRN--MSAMERFRNMDKRATTEDRNTAL 319
Query: 372 NSKHKNAINEIRIMKGSNGSAQVLSTIGRDGQLILWDLKTLSQKMSDLKI 521
+ H+N+I ++ I + + T G DG + +WD KTL + L+I
Sbjct: 320 ETLHQNSITQVSIYEVDKQDCRKFCTTGIDGAMTIWDFKTLESSIQGLRI 369
>sp|Q9WV32|ARC1B_MOUSE Actin-related protein 2/3 complex subunit 1B (ARP2/3 complex 41 kDa
subunit) (p41-ARC)
Length = 372
Score = 109 bits (273), Expect = 5e-24
Identities = 52/179 (29%), Positives = 99/179 (55%), Gaps = 5/179 (2%)
Frame = +3
Query: 3 SEGGLGWIHSIAFSNDGNKLIWSTHSSTICVATVSGSQQPPSVKMILMDNLPFLTLVWAA 182
S GW+H + FS G+++ W +H ST+C+ + + +V + + LP L + +
Sbjct: 198 SSSSCGWVHGVCFSASGSRVAWVSHDSTVCLVD---ADKKMAVATLASETLPLLAVTFIT 254
Query: 183 PNTVIGAGHDCVP--FTISTDKDQLKLGTSLDSKEELNTNATLSAKDRFRQIDRIATADS 356
N+++ AGHDC P FT L G LD ++ ++ ++A++RF+ +D+ A+++
Sbjct: 255 ENSLVAAGHDCFPVLFTYDNAAVTLSFGGRLDVPKQ-SSQRGMTARERFQNLDKKASSEG 313
Query: 357 NDSI---INSKHKNAINEIRIMKGSNGSAQVLSTIGRDGQLILWDLKTLSQKMSDLKIQ 524
+ ++S HKN++++I ++ G T G DG + +WD+K+L + DLKI+
Sbjct: 314 GAATGAGLDSLHKNSVSQISVLSGGKAKCSQFCTTGMDGGMSIWDVKSLESALKDLKIK 372
>sp|Q99PD4|ARC1A_RAT Actin-related protein 2/3 complex subunit 1A
Length = 370
Score = 109 bits (272), Expect = 7e-24
Identities = 57/170 (33%), Positives = 96/170 (56%), Gaps = 2/170 (1%)
Frame = +3
Query: 18 GWIHSIAFSNDGNKLIWSTHSSTICVATVSGSQQPPSVKMILMDNLPFLTLVWAAPNTVI 197
GW+H ++FS G++L W +H ST+ VA S S Q V + + LP L++ + + N+V+
Sbjct: 205 GWVHGVSFSASGSRLAWVSHDSTVSVADASKSVQ---VSTLRTEFLPLLSVSFVSENSVV 261
Query: 198 GAGHDCVPFTIS-TDKDQLKLGTSLD-SKEELNTNATLSAKDRFRQIDRIATADSNDSII 371
AGHDC P + D+ L + LD K+ + N +SA +RFR +D+ AT + ++ +
Sbjct: 262 AAGHDCCPMLFNYDDRGCLTFVSKLDVPKQSIQRN--MSAMERFRNMDKRATTEDRNTAL 319
Query: 372 NSKHKNAINEIRIMKGSNGSAQVLSTIGRDGQLILWDLKTLSQKMSDLKI 521
+ H+N+I ++ I + + T G DG + +WD KTL + L+I
Sbjct: 320 ETLHQNSITQVSIYEVDKQDCRKFCTTGIDGAMTIWDFKTLESSIQGLRI 369
>sp|P78774|ARPC1_SCHPO Probable ARP2/3 complex 41 kDa subunit (p41-ARC)
Length = 377
Score = 79.7 bits (195), Expect = 6e-15
Identities = 47/173 (27%), Positives = 88/173 (50%), Gaps = 17/173 (9%)
Frame = +3
Query: 18 GWIHSIAFSNDGNKLIWSTHSSTICVATVSGSQQPP-SVKMILMDNLPFLTLVWAAPNTV 194
GW+H++ FS GN L ++ H S++ +A S +QPP ++ + + LP +L+WA + +
Sbjct: 206 GWVHAVGFSPSGNALAYAGHDSSVTIAYPSAPEQPPRALITVKLSQLPLRSLLWANESAI 265
Query: 195 IGAGHDCVPFTISTDKD------QLKLGTSLDS----------KEELNTNATLSAKDRFR 326
+ AG++ P + ++ L GTS S +EE + + + FR
Sbjct: 266 VAAGYNYSPILLQGNESGWAHTRDLDAGTSKTSFTHTGNTGEGREEEGPVSFTALRSTFR 325
Query: 327 QIDRIATADSNDSIINSKHKNAINEIRIMKGSNGSAQVLSTIGRDGQLILWDL 485
+D ++ S S + + H+N I +R G+ G+ ++ G DG+++LW L
Sbjct: 326 NMDLKGSSQSISS-LPTVHQNMIATLRPYAGTPGNITAFTSSGTDGRVVLWTL 377
>sp|P38328|ARPC1_YEAST Probable ARP2/3 complex 41 kDa subunit (p41-ARC)
Length = 384
Score = 58.5 bits (140), Expect = 1e-08
Identities = 38/175 (21%), Positives = 77/175 (44%), Gaps = 20/175 (11%)
Frame = +3
Query: 21 WIHSIAFSNDGNKLIWSTHSSTICVATVSGSQQPPSVKMILMDNLPFLTLVWAAPNTVIG 200
+IH + + + ++ + H T+ V Q P + + LP+ +LVW + ++
Sbjct: 216 YIHDVEWRSQMERIAYVAHDGTLNVV----DYQSPVQSVNAPEGLPYRSLVWINDHEIVC 271
Query: 201 AGHDCVPFTISTDKDQLKLGTSLDSKEELNTNAT--------------------LSAKDR 320
G+ C P S + K +LD + ++A +SA +
Sbjct: 272 GGYSCHPVLFSEASEGWKFAKNLDKSDNNKSSALTASGNTDELSGNNDESSTFGISALRK 331
Query: 321 FRQIDRIATADSNDSIINSKHKNAINEIRIMKGSNGSAQVLSTIGRDGQLILWDL 485
F+++D ++ + S H+NAI E+R SNG +S+ G DG+++++ +
Sbjct: 332 FKELDLKGKVSTD--VQESAHENAIVELRPFAESNGQITQVSSCGLDGKIVIYTI 384
>sp|Q91VU6|WDR23_MOUSE WD-repeat protein 23
Length = 549
Score = 34.3 bits (77), Expect = 0.27
Identities = 39/190 (20%), Positives = 76/190 (40%), Gaps = 27/190 (14%)
Frame = +3
Query: 15 LGW-IHSIAFSNDGNKLIWSTHSSTICVATVSGSQQPPSVKMILMDNLPFLTLVWAAPN- 188
+GW + +AF+ DGN ++S+ S I + + G + + D F A +
Sbjct: 217 VGWSVLDVAFTPDGNHFLYSSWSDYIHICNIYGEGDTHTALDLRPDERRFAVFSIAVSSD 276
Query: 189 --TVIGAGHDCVPFTISTDKDQLKLGTSLDSKEELNTNATLSAKDRFRQIDRIATADSND 362
V+G +D + D++Q + ++S E+ ++ +A AD +
Sbjct: 277 GREVLGGANDGCLYVF--DREQNRRTLQIESHED--------------DVNAVAFADISS 320
Query: 363 SIINSKHKNAINEI---RIMK--------------------GSNGSAQVLSTIGRDGQLI 473
I+ S +AI ++ R M+ S G A+ L + +D +
Sbjct: 321 QILFSGGDDAICKVWDRRTMREDDPKPVGALAGHQDGITFIDSKGDARYLISNSKDQTIK 380
Query: 474 LWDLKTLSQK 503
LWD++ S +
Sbjct: 381 LWDIRRFSSR 390
>sp|Q8TEB1|WDR23_HUMAN WD-repeat protein 23
Length = 546
Score = 34.3 bits (77), Expect = 0.27
Identities = 39/190 (20%), Positives = 76/190 (40%), Gaps = 27/190 (14%)
Frame = +3
Query: 15 LGW-IHSIAFSNDGNKLIWSTHSSTICVATVSGSQQPPSVKMILMDNLPFLTLVWAAPN- 188
+GW + +AF+ DGN ++S+ S I + + G + + D F A +
Sbjct: 217 VGWSVLDVAFTPDGNHFLYSSWSDYIHICNIYGEGDTHTALDLRPDERRFAVFSIAVSSD 276
Query: 189 --TVIGAGHDCVPFTISTDKDQLKLGTSLDSKEELNTNATLSAKDRFRQIDRIATADSND 362
V+G +D + D++Q + ++S E+ ++ +A AD +
Sbjct: 277 GREVLGGANDGCLYVF--DREQNRRTLQIESHED--------------DVNAVAFADISS 320
Query: 363 SIINSKHKNAINEI---RIMK--------------------GSNGSAQVLSTIGRDGQLI 473
I+ S +AI ++ R M+ S G A+ L + +D +
Sbjct: 321 QILFSGGDDAICKVWDRRTMREDDPKPVGALAGHQDGITFIDSKGDARYLISNSKDQTIK 380
Query: 474 LWDLKTLSQK 503
LWD++ S +
Sbjct: 381 LWDIRRFSSR 390
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 72,225,457
Number of Sequences: 369166
Number of extensions: 1408904
Number of successful extensions: 3326
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3149
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3306
length of database: 68,354,980
effective HSP length: 106
effective length of database: 48,773,070
effective search space used: 5023626210
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)