Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_017_F08
(579 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q75WE7|LHR2A_RAT Loss of heterozygosity 11 chromosomal r... 45 1e-04
sp|Q99KC8|LHR2A_MOUSE Loss of heterozygosity 11 chromosomal... 42 0.001
sp|O00534|LHR2A_HUMAN Loss of heterozygosity 11 chromosomal... 42 0.001
sp|Q9NSV4|DIAP3_HUMAN Diaphanous protein homolog 3 (Diaphan... 30 4.3
sp|P53174|PRM8_YEAST Pheromone-regulated membrane protein 8... 29 7.4
sp|O58530|RGYR_PYRHO Reverse gyrase [Includes: Helicase ; T... 29 7.4
sp|P47906|RMAR_WILMR Mitochondrial ribosomal protein VAR1 29 7.4
sp|P53112|PEX14_YEAST Peroxisomal membrane protein PEX14 (P... 29 9.6
sp|O51750|MVIN_BORBU Virulence factor mviN homolog 29 9.6
>sp|Q75WE7|LHR2A_RAT Loss of heterozygosity 11 chromosomal region 2 gene A protein
homolog (Mast cell surface antigen 1) (Masa-1)
Length = 822
Score = 45.4 bits (106), Expect = 1e-04
Identities = 25/81 (30%), Positives = 38/81 (46%), Gaps = 1/81 (1%)
Frame = +1
Query: 232 DVIIFLIDQQNINGSWNYCEKILTKINIDAADFQNKKPKGITD-EIWITVLIYQYLVTKE 408
+V++ LI QN NGSW E + + D + P D W T+L +L
Sbjct: 689 NVVLQLIFLQNANGSWKLDENLTKILGTTLEDTKAANPSQHGDPSAWATILAVLWLHANG 748
Query: 409 QSREKEWRLVAKKAKQWIEDN 471
Q + EW L+ +KA W+ D+
Sbjct: 749 QDLKCEWELLERKAVAWLHDH 769
>sp|Q99KC8|LHR2A_MOUSE Loss of heterozygosity 11 chromosomal region 2 gene A protein
homolog
Length = 793
Score = 42.0 bits (97), Expect = 0.001
Identities = 23/81 (28%), Positives = 36/81 (44%), Gaps = 1/81 (1%)
Frame = +1
Query: 232 DVIIFLIDQQNINGSWNYCEKILTKINIDAADFQNKKPKGITD-EIWITVLIYQYLVTKE 408
+ ++ LI Q NGSW E + + + D + P D W TVL +L
Sbjct: 686 NAVVQLISLQKANGSWELDEDLTKILGTKSKDIKAANPAKHEDPSAWSTVLAVVWLHANG 745
Query: 409 QSREKEWRLVAKKAKQWIEDN 471
+ EW L+ +KA W+ D+
Sbjct: 746 TDLKCEWELLERKAVAWLHDH 766
>sp|O00534|LHR2A_HUMAN Loss of heterozygosity 11 chromosomal region 2 gene A protein
(Breast cancer suppressor candidate 1) (BCSC-1)
Length = 786
Score = 42.0 bits (97), Expect = 0.001
Identities = 21/76 (27%), Positives = 38/76 (50%), Gaps = 1/76 (1%)
Frame = +1
Query: 238 IIFLIDQQNINGSWNYCEKILTKINIDAADFQNKKPKGITDEI-WITVLIYQYLVTKEQS 414
++ LI QN NGSW+ E + + + + +P + D W T+L +L + +
Sbjct: 681 LVQLIYHQNANGSWDLNEDLAKILGMSLEEIMAAQPAELVDSSGWATILAVIWLHSNGKD 740
Query: 415 REKEWRLVAKKAKQWI 462
+ EW L+ +KA W+
Sbjct: 741 LKCEWELLERKAVAWM 756
>sp|Q9NSV4|DIAP3_HUMAN Diaphanous protein homolog 3 (Diaphanous-related formin-3) (DRF3)
Length = 1110
Score = 30.0 bits (66), Expect = 4.3
Identities = 12/34 (35%), Positives = 23/34 (67%)
Frame = +1
Query: 163 PKILKRSELCEEMKESKSVTKSIDVIIFLIDQQN 264
P I+ S CEE+K+SKS +K +++++ + + N
Sbjct: 818 PDIMAVSTACEEIKKSKSFSKLLELVLLMGNYMN 851
>sp|P53174|PRM8_YEAST Pheromone-regulated membrane protein 8 (DUP240 protein PRM8) (DUP1
protein)
Length = 237
Score = 29.3 bits (64), Expect = 7.4
Identities = 13/40 (32%), Positives = 22/40 (55%)
Frame = +1
Query: 352 ITDEIWITVLIYQYLVTKEQSREKEWRLVAKKAKQWIEDN 471
I+DE + L+ + + K + KEWR + K Q++ DN
Sbjct: 101 ISDEDFKCKLLMEIITRKPTVKGKEWRTITYKMNQYLFDN 140
>sp|O58530|RGYR_PYRHO Reverse gyrase [Includes: Helicase ; Topoisomerase ] [Contains: Pho
r-Gyr intein]
Length = 1624
Score = 29.3 bits (64), Expect = 7.4
Identities = 31/121 (25%), Positives = 55/121 (45%), Gaps = 6/121 (4%)
Frame = +1
Query: 163 PKILKRSEL-CEEMKESKSVTKSIDV---IIFLIDQQNINGSWNYCEKILTKINIDAADF 330
PK+ K L +E+K+ ++ S+ +I L+ ++ I Y + + T +
Sbjct: 1499 PKLEKGQRLRVKEVKQWRAPKVSLYTQGDVIALMKERGIGRPSTYAKIVQTLLQRGYVIE 1558
Query: 331 QNKKPKGITDEIWITVLIYQYLVTKEQS--REKEWRLVAKKAKQWIEDNVNYRDVLESIF 504
K K + E I V YQYL+TK + E+ R + K E +Y+DVL ++
Sbjct: 1559 TKGKKKLVPTEKGIKV--YQYLITKYKDLVSEERTRQLEKIMDMVEEAKADYQDVLNELY 1616
Query: 505 D 507
+
Sbjct: 1617 E 1617
>sp|P47906|RMAR_WILMR Mitochondrial ribosomal protein VAR1
Length = 380
Score = 29.3 bits (64), Expect = 7.4
Identities = 28/86 (32%), Positives = 45/86 (52%), Gaps = 4/86 (4%)
Frame = +2
Query: 254 INKISMDLGIIVKRFLQKLISMLLIFKTKNRRE*----QMKYGLLF*FINILLPKNKAER 421
INKI+ +L +V ++L I + ++FK KN ++ +K LLF ++ NK R
Sbjct: 269 INKITNEL--LVNKYL---IGLSMLFKGKNIKKAGVSRSIKEKLLFGSLS-----NKLYR 318
Query: 422 KNGDLLQKKRNNGSKIMLIIEMFWNR 499
KN LL K NN + L ++ N+
Sbjct: 319 KNSGLLVYKNNNNTTKYLNFDININK 344
>sp|P53112|PEX14_YEAST Peroxisomal membrane protein PEX14 (Peroxin-14)
Length = 341
Score = 28.9 bits (63), Expect = 9.6
Identities = 22/96 (22%), Positives = 49/96 (51%), Gaps = 6/96 (6%)
Frame = +1
Query: 253 DQQNINGSWNYCEKILTKINIDAADFQNKKPKGITDEIWITVLIYQYLVTKEQSREK--- 423
D++ I+ ++ + +L I + A+F+ K+ + + + + Q LV +SREK
Sbjct: 134 DKKEIDDQFSKIDTVLNAIEAEQAEFRKKESETLKELSDTIAELKQALVQTTRSREKIED 193
Query: 424 EWRLVAKKA---KQWIEDNVNYRDVLESIFDISMEL 522
E+R+V + + I+ V+ D ++ + +I E+
Sbjct: 194 EFRIVKLEVVNMQNTIDKFVSDNDGMQELNNIQKEM 229
>sp|O51750|MVIN_BORBU Virulence factor mviN homolog
Length = 512
Score = 28.9 bits (63), Expect = 9.6
Identities = 21/95 (22%), Positives = 40/95 (42%), Gaps = 22/95 (23%)
Frame = -1
Query: 480 IINIIFDPLFRFFCN--------KSPFFLSALF--------------FGNKILINQNSNP 367
++ ++F +F FF K+PF+LS LF +G L S
Sbjct: 359 LLGLLFYSMFGFFQKYYFSIRDAKTPFYLSVLFSILDIAISVFGINYYGLNALALAQSIS 418
Query: 366 YFICYSLRFFVLKISSIDINFCKNLFTIIPRSIDI 262
+ IC + +F++ + I+ + LF ++ I +
Sbjct: 419 FMICVIVFYFIILKRGVKIDLIEILFVLLKSIITL 453
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 60,446,270
Number of Sequences: 369166
Number of extensions: 1151776
Number of successful extensions: 3544
Number of sequences better than 10.0: 9
Number of HSP's better than 10.0 without gapping: 3351
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3515
length of database: 68,354,980
effective HSP length: 105
effective length of database: 48,957,805
effective search space used: 4259329035
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)