Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= Dr_sW_017_E05 (467 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|Q9UKR8|TNS16_HUMAN Tetraspanin-16 (Tspan-16) (Transmembr... 36 0.038 sp|P08962|CD63_HUMAN CD63 antigen (Melanoma-associated anti... 36 0.050 sp|O95858|TSN15_HUMAN Tetraspanin-15 (Tspan-15) (Transmembr... 34 0.14 sp|P28648|CD63_RAT CD63 antigen (AD1 antigen) 33 0.32 sp|Q28709|CD63_RABIT CD63 antigen 33 0.32 sp|Q8BJU2|TSN9_MOUSE Tetraspanin-9 (Tspan-9) (Tetraspan NET-5) 32 0.72 sp|Q8NG11|TSN14_HUMAN Tetraspanin-14 (Tspan-14) (Transmembr... 32 0.72 sp|O75954|TSN9_HUMAN Tetraspanin-9 (Tspan-9) (Tetraspan NET-5) 32 0.93 sp|Q8QZY6|TSN14_MOUSE Tetraspanin-14 (Tspan-14) (Transmembr... 31 1.2 sp|P41731|CD63_MOUSE CD63 antigen 31 1.6
>sp|Q9UKR8|TNS16_HUMAN Tetraspanin-16 (Tspan-16) (Transmembrane 4 superfamily member 16) (Tetraspanin TM4-B) Length = 245 Score = 36.2 bits (82), Expect = 0.038 Identities = 20/77 (25%), Positives = 32/77 (41%) Frame = +1 Query: 7 DLIQAKFKCCGASSSADFVANTGYNKSYGIIPFSCCMMVGQTLTPADSNCTYYPTVNNSY 186 +L+ K KCCG ++ DF ++ + P SCC +G +C N Sbjct: 145 NLVMEKLKCCGVNNYTDFSGSSFEMTTGHTYPRSCCKSIGSV------SCDGRDVSPNVI 198 Query: 187 FNTGCYSQLWNIINSYS 237 GC+ +L I + S Sbjct: 199 HQKGCFHKLLKITKTQS 215
>sp|P08962|CD63_HUMAN CD63 antigen (Melanoma-associated antigen ME491) (Lysosome-associated membrane glycoprotein 3) (LAMP-3) (Ocular melanoma-associated antigen) (OMA81H) (Granulophysin) (Tetraspanin-30) (Tspan-30) Length = 238 Score = 35.8 bits (81), Expect = 0.050 Identities = 17/41 (41%), Positives = 26/41 (63%) Frame = +1 Query: 1 IIDLIQAKFKCCGASSSADFVANTGYNKSYGIIPFSCCMMV 123 I+D +QA FKCCGA++ D+ +K+ +P SCC+ V Sbjct: 135 ILDRMQADFKCCGAANYTDWEKIPSMSKNR--VPDSCCINV 173
>sp|O95858|TSN15_HUMAN Tetraspanin-15 (Tspan-15) (Transmembrane 4 superfamily member 15) (Tetraspan NET-7) Length = 294 Score = 34.3 bits (77), Expect = 0.14 Identities = 19/69 (27%), Positives = 33/69 (47%), Gaps = 5/69 (7%) Frame = +1 Query: 1 IIDLIQAKFKCCGASSSADFVANTGYNKSYG-----IIPFSCCMMVGQTLTPADSNCTYY 165 I+D +Q KFKCCG D+ N ++ S +P++CC+ + T + Y Sbjct: 144 IMDFVQKKFKCCGGEDYRDWSKNQYHDCSAPGPLACGVPYTCCI---RNTTEVVNTMCGY 200 Query: 166 PTVNNSYFN 192 T++ F+ Sbjct: 201 KTIDKERFS 209
>sp|P28648|CD63_RAT CD63 antigen (AD1 antigen) Length = 238 Score = 33.1 bits (74), Expect = 0.32 Identities = 16/41 (39%), Positives = 24/41 (58%) Frame = +1 Query: 1 IIDLIQAKFKCCGASSSADFVANTGYNKSYGIIPFSCCMMV 123 I+D +Q + KCCGAS+ D+ G K +P SCC+ + Sbjct: 135 ILDKLQKENKCCGASNYTDWERIPGMAKDR--VPDSCCINI 173
>sp|Q28709|CD63_RABIT CD63 antigen Length = 238 Score = 33.1 bits (74), Expect = 0.32 Identities = 15/41 (36%), Positives = 23/41 (56%) Frame = +1 Query: 1 IIDLIQAKFKCCGASSSADFVANTGYNKSYGIIPFSCCMMV 123 I+D +Q F CCGA++ D+ G + +P SCC+ V Sbjct: 135 ILDRMQKDFTCCGAANYTDWATIPGMTRDR--VPDSCCVNV 173
>sp|Q8BJU2|TSN9_MOUSE Tetraspanin-9 (Tspan-9) (Tetraspan NET-5) Length = 239 Score = 32.0 bits (71), Expect = 0.72 Identities = 22/72 (30%), Positives = 31/72 (43%), Gaps = 2/72 (2%) Frame = +1 Query: 7 DLIQAKFKCCGASSSADFVANTGYNKSYGIIPFSCCMMVGQTLTPADSNCTYYPTVNNSY 186 ++IQA+ +CCG + D+ G N +P CCM Q C T Sbjct: 139 NIIQAEMRCCGVTDYTDWYPVLGEN----TVPDRCCMENSQ-------GCGRNST--TPL 185 Query: 187 FNTGCYS--QLW 216 + TGCY +LW Sbjct: 186 WRTGCYEKVKLW 197
>sp|Q8NG11|TSN14_HUMAN Tetraspanin-14 (Tspan-14) (Transmembrane 4 superfamily member 14) (DC-TM4F2) Length = 270 Score = 32.0 bits (71), Expect = 0.72 Identities = 24/83 (28%), Positives = 32/83 (38%), Gaps = 12/83 (14%) Frame = +1 Query: 1 IIDLIQAKFKCCGASSSADFVANTGYNKSYGI-------IPFSCCM-----MVGQTLTPA 144 +ID +Q +CCGA D+ N +N S +PFSCC+ V T Sbjct: 143 LIDSLQKANQCCGAYGPEDWDLNVYFNCSGASYSREKCGVPFSCCVPDPAQKVVNTQCGY 202 Query: 145 DSNCTYYPTVNNSYFNTGCYSQL 213 D + S F GC L Sbjct: 203 DVRIQLKSKWDESIFTKGCIQAL 225
>sp|O75954|TSN9_HUMAN Tetraspanin-9 (Tspan-9) (Tetraspan NET-5) Length = 239 Score = 31.6 bits (70), Expect = 0.93 Identities = 20/69 (28%), Positives = 30/69 (43%) Frame = +1 Query: 7 DLIQAKFKCCGASSSADFVANTGYNKSYGIIPFSCCMMVGQTLTPADSNCTYYPTVNNSY 186 ++IQA+ +CCG + D+ G N +P CCM Q N T Sbjct: 139 NIIQAEMRCCGVTDYTDWYPVLGEN----TVPDRCCMENSQ---GCGRNAT------TPL 185 Query: 187 FNTGCYSQL 213 + TGCY ++ Sbjct: 186 WRTGCYEKV 194
>sp|Q8QZY6|TSN14_MOUSE Tetraspanin-14 (Tspan-14) (Transmembrane 4 superfamily member 14) Length = 270 Score = 31.2 bits (69), Expect = 1.2 Identities = 16/46 (34%), Positives = 23/46 (50%), Gaps = 7/46 (15%) Frame = +1 Query: 1 IIDLIQAKFKCCGASSSADFVANTGYNKSYGI-------IPFSCCM 117 +ID +Q +CCGA D+ N +N S +PFSCC+ Sbjct: 143 LIDSLQKANQCCGAYGPEDWDLNVYFNCSGASYSREKCGVPFSCCV 188
>sp|P41731|CD63_MOUSE CD63 antigen Length = 238 Score = 30.8 bits (68), Expect = 1.6 Identities = 15/41 (36%), Positives = 23/41 (56%) Frame = +1 Query: 1 IIDLIQAKFKCCGASSSADFVANTGYNKSYGIIPFSCCMMV 123 I+D +Q + CCGAS+ D+ G K +P SCC+ + Sbjct: 135 ILDKLQKENNCCGASNYTDWENIPGMAKDR--VPDSCCINI 173
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 49,907,330 Number of Sequences: 369166 Number of extensions: 879309 Number of successful extensions: 1928 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 1910 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 1926 length of database: 68,354,980 effective HSP length: 101 effective length of database: 49,696,745 effective search space used: 2683624230 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)