Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_017_E03
(883 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9UG63|ABCF2_HUMAN ATP-binding cassette sub-family F mem... 382 e-106
sp|Q99LE6|ABCF2_MOUSE ATP-binding cassette sub-family F mem... 382 e-106
sp|P40024|YEM6_YEAST Probable ATP-dependent transporter YER... 252 8e-67
sp|P43535|GCN20_YEAST Protein GCN20 214 2e-55
sp|Q6MG08|ABCF1_RAT ATP-binding cassette sub-family F membe... 189 1e-47
sp|Q6P542|ABCF1_MOUSE ATP-binding cassette sub-family F mem... 187 3e-47
sp|Q8NE71|ABCF1_HUMAN ATP-binding cassette sub-family F mem... 187 4e-47
sp|Q7YR37|ABCF1_PANTR ATP-binding cassette sub-family F mem... 187 4e-47
sp|Q767L0|ABCF1_PIG ATP-binding cassette sub-family F member 1 186 7e-47
sp|P63390|YHES_ECO57 Hypothetical ABC transporter ATP-bindi... 144 4e-34
>sp|Q9UG63|ABCF2_HUMAN ATP-binding cassette sub-family F member 2 (Iron-inhibited ABC
transporter 2)
Length = 623
Score = 382 bits (980), Expect = e-106
Identities = 181/266 (68%), Positives = 221/266 (83%)
Frame = +3
Query: 15 KLARQAQSKEKTLKKMVDGGLTQKVIREKNLVFSFPSCGEIPPPVIQVQNVSFKYGANKP 194
KLARQAQSKEKTL+KM+ GLT++V+ +K L F FP CG+IPPPVI VQNVSFKY + P
Sbjct: 351 KLARQAQSKEKTLQKMMASGLTERVVSDKTLSFYFPPCGKIPPPVIMVQNVSFKYTKDGP 410
Query: 195 LIYDNIDFGVDLDTRVALVGPNGAGKSTLLKLIASELEPTDGLIRRHSKCRIGRYHQHLH 374
IY+N++FG+DLDTRVALVGPNGAGKSTLLKL+ EL PTDG+IR+HS +IGRYHQHL
Sbjct: 411 CIYNNLEFGIDLDTRVALVGPNGAGKSTLLKLLTGELLPTDGMIRKHSHVKIGRYHQHLQ 470
Query: 375 EILDLNSTALEWMMKSFPHIKEKDEMRKKLGRYGLTGGQQICPIKSLSDGQRCRIIFAWL 554
E LDL+ + LE+MMK +P IKEK+EMRK +GRYGLTG QQ+ PI++LSDGQ+CR+ AWL
Sbjct: 471 EQLDLDLSPLEYMMKCYPEIKEKEEMRKIIGRYGLTGKQQVSPIRNLSDGQKCRVCLAWL 530
Query: 555 AEGCPHMLLLDEPTNHLDLETIDSLADAINEFEGGLLLVSHDFRLIGRVAEEIWVCDHGA 734
A PHML LDEPTNHLD+ETID+LADAINEFEGG++LVSHDFRLI +VA+EIWVC+
Sbjct: 531 AWQNPHMLFLDEPTNHLDIETIDALADAINEFEGGMMLVSHDFRLIQQVAQEIWVCEKQT 590
Query: 735 VTKWPGDIYSYKTSLIKEIEREHTRM 812
+TKWPGDI +YK L ++ E ++
Sbjct: 591 ITKWPGDILAYKEHLKSKLVDEEPQL 616
Score = 60.8 bits (146), Expect = 5e-09
Identities = 63/221 (28%), Positives = 89/221 (40%), Gaps = 25/221 (11%)
Frame = +3
Query: 237 RVALVGPNGAGKSTLLKLIAS----------------ELEPTDGLIRRHSKCRIGRYHQH 368
R L+G NG GKS LL I E+ P+D H +
Sbjct: 113 RYGLIGLNGIGKSMLLSAIGKREVPIPEHIDIYHLTREMPPSDKT-PLHCVMEVDTERAM 171
Query: 369 LH---EILDLNSTALEWMMKSFPHIKEKD----EMRKK--LGRYGLTGGQQICPIKSLSD 521
L E L E +M+ + ++E D EMR L G T Q +K S
Sbjct: 172 LEKEAERLAHEDAECEKLMELYERLEELDADKAEMRASRILHGLGFTPAMQRKKLKDFSG 231
Query: 522 GQRCRIIFAWLAEGCPHMLLLDEPTNHLDLETIDSLADAINEFEGGLLLVSHDFRLIGRV 701
G R R+ A P MLLLDEPTNHLDL+ L + + F+ L+LVSH + V
Sbjct: 232 GWRMRVALARALFIRPFMLLLDEPTNHLDLDACVWLEEELKTFKRILVLVSHSQDFLNGV 291
Query: 702 AEEIWVCDHGAVTKWPGDIYSYKTSLIKEIEREHTRMMTER 824
I + + + G+ Y + ++ E + R E+
Sbjct: 292 CTNIIHMHNKKLKYYTGNYDQYVKTRLELEENQMKRFHWEQ 332
>sp|Q99LE6|ABCF2_MOUSE ATP-binding cassette sub-family F member 2
Length = 628
Score = 382 bits (980), Expect = e-106
Identities = 181/266 (68%), Positives = 221/266 (83%)
Frame = +3
Query: 15 KLARQAQSKEKTLKKMVDGGLTQKVIREKNLVFSFPSCGEIPPPVIQVQNVSFKYGANKP 194
KLARQAQSKEKTL+KM+ GLT++V+ +K L F FP CG+IPPPVI VQNVSFKY + P
Sbjct: 356 KLARQAQSKEKTLQKMMASGLTERVVSDKTLSFYFPPCGKIPPPVIMVQNVSFKYTKDGP 415
Query: 195 LIYDNIDFGVDLDTRVALVGPNGAGKSTLLKLIASELEPTDGLIRRHSKCRIGRYHQHLH 374
IY+N++FG+DLDTRVALVGPNGAGKSTLLKL+ EL PTDG+IR+HS +IGRYHQHL
Sbjct: 416 CIYNNLEFGIDLDTRVALVGPNGAGKSTLLKLLTGELLPTDGMIRKHSHVKIGRYHQHLQ 475
Query: 375 EILDLNSTALEWMMKSFPHIKEKDEMRKKLGRYGLTGGQQICPIKSLSDGQRCRIIFAWL 554
E LDL+ + LE+MMK +P IKEK+EMRK +GRYGLTG QQ+ PI++LSDGQ+CR+ AWL
Sbjct: 476 EQLDLDLSPLEYMMKCYPEIKEKEEMRKIIGRYGLTGKQQVSPIRNLSDGQKCRVCLAWL 535
Query: 555 AEGCPHMLLLDEPTNHLDLETIDSLADAINEFEGGLLLVSHDFRLIGRVAEEIWVCDHGA 734
A PHML LDEPTNHLD+ETID+LADAINEFEGG++LVSHDFRLI +VA+EIWVC+
Sbjct: 536 AWQNPHMLFLDEPTNHLDIETIDALADAINEFEGGMMLVSHDFRLIQQVAQEIWVCEKQT 595
Query: 735 VTKWPGDIYSYKTSLIKEIEREHTRM 812
+TKWPGDI +YK L ++ E ++
Sbjct: 596 ITKWPGDILAYKEHLKSKLVDEEPQL 621
Score = 58.2 bits (139), Expect = 3e-08
Identities = 62/220 (28%), Positives = 87/220 (39%), Gaps = 24/220 (10%)
Frame = +3
Query: 237 RVALVGPNGAGKSTLLKLIASELEPTDGLIRRHSKCR---------------IGRYHQHL 371
R L+G NG GKS LL I P I + R + L
Sbjct: 118 RYGLIGLNGIGKSMLLSAIGKREVPIPEHIDIYHLTREMPPSEKTPLQCVMEVDTERAML 177
Query: 372 H---EILDLNSTALEWMMKSFPHIKEKD----EMRKK--LGRYGLTGGQQICPIKSLSDG 524
E L E +M+ + ++E D EMR L G T Q +K S G
Sbjct: 178 EREAERLAHEDAECEKLMELYERLEELDADKAEMRASRILHGLGFTPAMQRKKLKDFSGG 237
Query: 525 QRCRIIFAWLAEGCPHMLLLDEPTNHLDLETIDSLADAINEFEGGLLLVSHDFRLIGRVA 704
R R+ A P MLLLDEPTNHLDL+ L + + F+ L+LVSH + V
Sbjct: 238 WRMRVALARALFIRPFMLLLDEPTNHLDLDACVWLEEELKTFKRILVLVSHSQDFLNGVC 297
Query: 705 EEIWVCDHGAVTKWPGDIYSYKTSLIKEIEREHTRMMTER 824
I + + + G+ Y + ++ E + R E+
Sbjct: 298 TNIIHMHNKKLKYYTGNYDQYVKTRLELEENQMKRFHWEQ 337
>sp|P40024|YEM6_YEAST Probable ATP-dependent transporter YER036C
Length = 610
Score = 252 bits (644), Expect = 8e-67
Identities = 125/260 (48%), Positives = 180/260 (69%), Gaps = 2/260 (0%)
Frame = +3
Query: 18 LARQAQSKEKTLKKMVDGGLTQKVIREKNLVFSFPSCGEIPPPVIQVQNVSFKYGAN-KP 194
L +QA+S++K L KM GL Q V+ +K F FP +PPPV+ ++SF Y +N
Sbjct: 349 LVKQAKSRQKILDKMEADGLVQPVVPDKVFSFRFPQVERLPPPVLAFDDISFHYESNPSE 408
Query: 195 LIYDNIDFGVDLDTRVALVGPNGAGKSTLLKLIASELEPTDGLIRRHSKCRIGRYHQHLH 374
+Y++++FGVD+D+R+ALVGPNG GKSTLLK++ EL P G + RH+ ++G Y QH
Sbjct: 409 NLYEHLNFGVDMDSRIALVGPNGVGKSTLLKIMTGELTPQSGRVSRHTHVKLGVYSQHSQ 468
Query: 375 EILDLNSTALEWMMKSFPHIKEKDEM-RKKLGRYGLTGGQQICPIKSLSDGQRCRIIFAW 551
+ LDL +ALE++ + +I + + R +LGRYGLTG Q + +LS+GQR R++FA
Sbjct: 469 DQLDLTKSALEFVRDKYSNISQDFQFWRGQLGRYGLTGEGQTVQMATLSEGQRSRVVFAL 528
Query: 552 LAEGCPHMLLLDEPTNHLDLETIDSLADAINEFEGGLLLVSHDFRLIGRVAEEIWVCDHG 731
LA P++LLLDEPTN LD+ TIDSLADAINEF GG+++VSHDFRL+ ++A++I+V ++
Sbjct: 529 LALEQPNVLLLDEPTNGLDIPTIDSLADAINEFNGGVVVVSHDFRLLDKIAQDIFVVENK 588
Query: 732 AVTKWPGDIYSYKTSLIKEI 791
T+W G I YK L K +
Sbjct: 589 TATRWDGSILQYKNKLAKNV 608
Score = 51.6 bits (122), Expect = 3e-06
Identities = 61/235 (25%), Positives = 101/235 (42%), Gaps = 29/235 (12%)
Frame = +3
Query: 150 IQVQNVSFKYGANKPLIYDNIDFGVDLD--TRVALVGPNGAGKSTLLKLIA--------- 296
I++ +VS + K LI D+ G++L+ R L+G NG GKST LK +A
Sbjct: 82 IKLSSVSLLFHG-KVLIQDS---GLELNYGRRYGLLGENGCGKSTFLKALATREYPIPEH 137
Query: 297 ------------SELEPTDGLIRRHSKCRIGRYHQHLHEILDLNSTALEWMMKSFPHIKE 440
SEL D ++ ++ + R + + + + E + + +
Sbjct: 138 IDIYLLDEPAEPSELSALDYVVTE-AQHELKRIEDLVEKTILEDGPESELLEPLYERMDS 196
Query: 441 KD----EMRKKLGRYGLTGGQQ--ICPIKSLSDGQRCRIIFAWLAEGCPHMLLLDEPTNH 602
D E R + GL ++ + K +S G + R+ A P +LLLD+PT H
Sbjct: 197 LDPDTFESRAAIILIGLGFNKKTILKKTKDMSGGWKMRVALAKALFVKPTLLLLDDPTAH 256
Query: 603 LDLETIDSLADAINEFEGGLLLVSHDFRLIGRVAEEIWVCDHGAVTKWPGDIYSY 767
LDLE L + + F+ L+LVSH + V + +T + G+ SY
Sbjct: 257 LDLEACVWLEEYLKRFDRTLVLVSHSQDFLNGVCTNMIDMRAQKLTAYGGNYDSY 311
>sp|P43535|GCN20_YEAST Protein GCN20
Length = 752
Score = 214 bits (546), Expect = 2e-55
Identities = 106/258 (41%), Positives = 170/258 (65%)
Frame = +3
Query: 21 ARQAQSKEKTLKKMVDGGLTQKVIREKNLVFSFPSCGEIPPPVIQVQNVSFKYGANKPLI 200
+++AQS+ K L+K+ + + ++K + F FP C ++ PP+IQ+Q+VSF Y N L+
Sbjct: 492 SQEAQSRIKKLEKLP---VLEPPEQDKTIDFKFPECDKLSPPIIQLQDVSFGYDENNLLL 548
Query: 201 YDNIDFGVDLDTRVALVGPNGAGKSTLLKLIASELEPTDGLIRRHSKCRIGRYHQHLHEI 380
D ++ V +D+R+ALVG NG GK+TLLK++ +L P G + R+ + RIG + QH +
Sbjct: 549 KD-VNLDVQMDSRIALVGANGCGKTTLLKIMMEQLRPLKGFVSRNPRLRIGYFTQHHVDS 607
Query: 381 LDLNSTALEWMMKSFPHIKEKDEMRKKLGRYGLTGGQQICPIKSLSDGQRCRIIFAWLAE 560
+DL ++A++WM KSFP K +E R+ LG +G+TG + ++ LS GQ+ R+ FA L
Sbjct: 608 MDLTTSAVDWMSKSFPG-KTDEEYRRHLGSFGITGTLGLQKMQLLSGGQKSRVAFAALCL 666
Query: 561 GCPHMLLLDEPTNHLDLETIDSLADAINEFEGGLLLVSHDFRLIGRVAEEIWVCDHGAVT 740
PH+L+LDEP+NHLD +D+L +A+ F GG+L+VSHD +I V +EIWV + G V
Sbjct: 667 NNPHILVLDEPSNHLDTTGLDALVEALKNFNGGVLMVSHDISVIDSVCKEIWVSEQGTVK 726
Query: 741 KWPGDIYSYKTSLIKEIE 794
++ G IY Y+ +++ +
Sbjct: 727 RFEGTIYDYRDYILQSAD 744
Score = 56.6 bits (135), Expect = 9e-08
Identities = 72/263 (27%), Positives = 101/263 (38%), Gaps = 54/263 (20%)
Frame = +3
Query: 198 IYDNIDFGVDLDTRVALVGPNGAGKSTLLKLIAS-ELEPTDGLIRRHSKCRI-GRYHQHL 371
I N + R LVG NG GKSTLL+ ++ EL + H + + G + L
Sbjct: 214 ILSNAQLTLSFGHRYGLVGQNGIGKSTLLRALSRRELNVPKHVSILHVEQELRGDDTKAL 273
Query: 372 HEILDLN---STALEWMMKSFPHIKEKDEMR----------KKLGR-------------- 470
+LD + L K +KE D +R KKL
Sbjct: 274 QSVLDADVWRKQLLSEEAKINERLKEMDVLRQEFEEDSLEVKKLDNEREDLDNHLIQISD 333
Query: 471 ------------------YGL---TGGQQICPIKSLSDGQRCRIIFAWLAEGCPHMLLLD 587
YGL T QQ P S S G R R+ A P +LLLD
Sbjct: 334 KLVDMESDKAEARAASILYGLGFSTEAQQQ-PTNSFSGGWRMRLSLARALFCQPDLLLLD 392
Query: 588 EPTNHLDLETIDSLADAINEFEGGLLLVSHDFRLIGRVAEEIWVCDHGAVTKWPGD---- 755
EP+N LD+ +I LA+ + + +L VSHD + VA +I + + + G
Sbjct: 393 EPSNMLDVPSIAYLAEYLKTYPNTVLTVSHDRAFLNEVATDIIYQHNERLDYYRGQDFDT 452
Query: 756 IYSYKTSLIKEIEREHTRMMTER 824
Y+ K K +RE+ M R
Sbjct: 453 FYTTKEERRKNAQREYDNQMVYR 475
>sp|Q6MG08|ABCF1_RAT ATP-binding cassette sub-family F member 1 (ATP-binding cassette 50)
Length = 839
Score = 189 bits (479), Expect = 1e-47
Identities = 97/233 (41%), Positives = 153/233 (65%)
Frame = +3
Query: 93 REKNLVFSFPSCGEIPPPVIQVQNVSFKYGANKPLIYDNIDFGVDLDTRVALVGPNGAGK 272
RE + F+FP + PPV+ + V+F Y KPL + N+DFG+D+D+R+ +VGPNG GK
Sbjct: 600 REYTVRFTFPDPPPLSPPVLGLHGVTFGYEGQKPL-FKNLDFGIDMDSRICIVGPNGVGK 658
Query: 273 STLLKLIASELEPTDGLIRRHSKCRIGRYHQHLHEILDLNSTALEWMMKSFPHIKEKDEM 452
STLL L+ +L PT+G +R++ + +IG ++Q E L + T E++ + F ++ +D
Sbjct: 659 STLLLLLTGKLTPTNGEMRKNHRLKIGFFNQQYAEQLHMEETPTEYLQRGF-NLPYQDA- 716
Query: 453 RKKLGRYGLTGGQQICPIKSLSDGQRCRIIFAWLAEGCPHMLLLDEPTNHLDLETIDSLA 632
RK LGR+GL I LS GQ+ R++FA LA P +L+LDEPTN+LD+E+ID+L
Sbjct: 717 RKCLGRFGLESHAHTIQICKLSGGQKARVVFAELACREPDVLILDEPTNNLDIESIDALG 776
Query: 633 DAINEFEGGLLLVSHDFRLIGRVAEEIWVCDHGAVTKWPGDIYSYKTSLIKEI 791
+AINE++G +++VSHD RLI ++WV + +V++ GD YK +++ +
Sbjct: 777 EAINEYKGAVIVVSHDARLITETNCQLWVVEEQSVSQIDGDFDDYKREVLEAL 829
Score = 75.1 bits (183), Expect = 2e-13
Identities = 79/314 (25%), Positives = 133/314 (42%), Gaps = 45/314 (14%)
Frame = +3
Query: 6 ARGKLARQAQSKEKTLKKMVDGGLTQKVIREKNLV---FSFPSCGEIPPPVIQVQNVS-- 170
A A ++ ++K LKK +D + ++ N FS S E+ ++N S
Sbjct: 240 ANDPYAHLSKKEKKKLKKQMDYERQVESLKAANAAENDFSV-SQAEVSSRQAMLENASDI 298
Query: 171 ----FKYGANKPLIYDNIDFGVDLDTRVALVGPNGAGKSTLLK----------------- 287
F A+ ++ N D + R LVGPNG GK+TLLK
Sbjct: 299 KLEKFSISAHGKELFVNADLYIVAGRRYGLVGPNGKGKTTLLKHIANRALSIPPNIDVLL 358
Query: 288 ----LIASELEPTDGLIRRHSK-CRIGRYHQHLHEILDL-NSTALEWMMKSFPHIKE--- 440
++A E ++R +K R+ + L L+ + TA E + K + ++
Sbjct: 359 CEQEVVADETPAVQAVLRADTKRLRLLEEEKRLQGQLEQGDDTAAEKLEKVYEELRATGA 418
Query: 441 ---KDEMRKKLGRYGLTGGQQICPIKSLSDGQRCRIIFAWLAEGCPHMLLLDEPTNHLDL 611
+ + R+ L G Q P + S G R R+ A P +L+LDEPTNHLDL
Sbjct: 419 AAAEAKARRILAGLGFDPEMQNRPTQKFSGGWRMRVSLARALFMEPTLLMLDEPTNHLDL 478
Query: 612 ETIDSLADAINEFEGGLLLVSHDFRLIGRVAEEIWVCDHGAVTKWPGDIYSYK------- 770
+ L + + + LL+VSHD + V +I D + + G+ ++K
Sbjct: 479 NAVIWLNNYLQGWRKTLLIVSHDQGFLDDVCTDIIHLDTQRLHYYRGNYMTFKKMYQQKQ 538
Query: 771 TSLIKEIEREHTRM 812
L+K+ E++ ++
Sbjct: 539 KELLKQYEKQEKKL 552
>sp|Q6P542|ABCF1_MOUSE ATP-binding cassette sub-family F member 1
Length = 837
Score = 187 bits (476), Expect = 3e-47
Identities = 96/233 (41%), Positives = 153/233 (65%)
Frame = +3
Query: 93 REKNLVFSFPSCGEIPPPVIQVQNVSFKYGANKPLIYDNIDFGVDLDTRVALVGPNGAGK 272
+E + F+FP + PPV+ + V+F Y KPL + N+DFG+D+D+R+ +VGPNG GK
Sbjct: 598 KEYTVRFTFPDPPPLSPPVLGLHGVTFGYEGQKPL-FKNLDFGIDMDSRICIVGPNGVGK 656
Query: 273 STLLKLIASELEPTDGLIRRHSKCRIGRYHQHLHEILDLNSTALEWMMKSFPHIKEKDEM 452
STLL L+ +L PT+G +R++ + +IG ++Q E L + T E++ +SF ++ +D
Sbjct: 657 STLLLLLTGKLTPTNGEMRKNHRLKIGFFNQQYAEQLHMEETPTEYLQRSF-NLPYQDA- 714
Query: 453 RKKLGRYGLTGGQQICPIKSLSDGQRCRIIFAWLAEGCPHMLLLDEPTNHLDLETIDSLA 632
RK LGR+GL I LS GQ+ R++FA LA P +L+LDEPTN+LD+E+ID+L
Sbjct: 715 RKCLGRFGLESHAHTIQICKLSGGQKARVVFAELACREPDVLILDEPTNNLDIESIDALG 774
Query: 633 DAINEFEGGLLLVSHDFRLIGRVAEEIWVCDHGAVTKWPGDIYSYKTSLIKEI 791
+AIN+++G +++VSHD RLI ++WV + V++ GD YK +++ +
Sbjct: 775 EAINDYKGAVIVVSHDARLITETNCQLWVVEEQGVSQIDGDFDDYKREVLEAL 827
Score = 75.1 bits (183), Expect = 2e-13
Identities = 79/314 (25%), Positives = 133/314 (42%), Gaps = 45/314 (14%)
Frame = +3
Query: 6 ARGKLARQAQSKEKTLKKMVDGGLTQKVIREKNLV---FSFPSCGEIPPPVIQVQNVS-- 170
A A ++ ++K LKK +D + ++ N FS S E+ ++N S
Sbjct: 238 ANDPYANLSKKEKKKLKKQMDYERQVESLKAANAAENDFSV-SQAEVSSRQAMLENASDI 296
Query: 171 ----FKYGANKPLIYDNIDFGVDLDTRVALVGPNGAGKSTLLK----------------- 287
F A+ ++ N D + R LVGPNG GK+TLLK
Sbjct: 297 KLEKFSISAHGKELFVNADLYIVAGRRYGLVGPNGKGKTTLLKHIANRALSIPPNIDVLL 356
Query: 288 ----LIASELEPTDGLIRRHSK-CRIGRYHQHLHEILDL-NSTALEWMMKSFPHIKE--- 440
++A E ++R +K R+ + L L+ + TA E + K + ++
Sbjct: 357 CEQEVVADETPAVQAVLRADTKRLRLLEEERRLQGQLEQGDDTAAEKLEKVYEELRATGA 416
Query: 441 ---KDEMRKKLGRYGLTGGQQICPIKSLSDGQRCRIIFAWLAEGCPHMLLLDEPTNHLDL 611
+ + R+ L G Q P + S G R R+ A P +L+LDEPTNHLDL
Sbjct: 417 AAAEAKARRILAGLGFDPEMQNRPTQKFSGGWRMRVSLARALFMEPTLLMLDEPTNHLDL 476
Query: 612 ETIDSLADAINEFEGGLLLVSHDFRLIGRVAEEIWVCDHGAVTKWPGDIYSYK------- 770
+ L + + + LL+VSHD + V +I D + + G+ ++K
Sbjct: 477 NAVIWLNNYLQGWRKTLLIVSHDQGFLDDVCTDIIHLDTQRLHYYRGNYMTFKKMYQQKQ 536
Query: 771 TSLIKEIEREHTRM 812
L+K+ E++ ++
Sbjct: 537 KELLKQYEKQEKKL 550
>sp|Q8NE71|ABCF1_HUMAN ATP-binding cassette sub-family F member 1 (ATP-binding cassette 50)
(TNF-alpha-stimulated ABC protein)
Length = 845
Score = 187 bits (474), Expect = 4e-47
Identities = 96/233 (41%), Positives = 152/233 (65%)
Frame = +3
Query: 93 REKNLVFSFPSCGEIPPPVIQVQNVSFKYGANKPLIYDNIDFGVDLDTRVALVGPNGAGK 272
+E + F+FP + PPV+ + V+F Y KPL + N+DFG+D+D+R+ +VGPNG GK
Sbjct: 606 KEYTVRFTFPDPPPLSPPVLGLHGVTFGYQGQKPL-FKNLDFGIDMDSRICIVGPNGVGK 664
Query: 273 STLLKLIASELEPTDGLIRRHSKCRIGRYHQHLHEILDLNSTALEWMMKSFPHIKEKDEM 452
STLL L+ +L PT G +R++ + +IG ++Q E L + T E++ + F ++ +D
Sbjct: 665 STLLLLLTGKLTPTHGEMRKNHRLKIGFFNQQYAEQLRMEETPTEYLQRGF-NLPYQDA- 722
Query: 453 RKKLGRYGLTGGQQICPIKSLSDGQRCRIIFAWLAEGCPHMLLLDEPTNHLDLETIDSLA 632
RK LGR+GL I LS GQ+ R++FA LA P +L+LDEPTN+LD+E+ID+L
Sbjct: 723 RKCLGRFGLESHAHTIQICKLSGGQKARVVFAELACREPDVLILDEPTNNLDIESIDALG 782
Query: 633 DAINEFEGGLLLVSHDFRLIGRVAEEIWVCDHGAVTKWPGDIYSYKTSLIKEI 791
+AINE++G +++VSHD RLI ++WV + +V++ GD YK +++ +
Sbjct: 783 EAINEYKGAVIVVSHDARLITETNCQLWVVEEQSVSQIDGDFEDYKREVLEAL 835
Score = 70.5 bits (171), Expect = 6e-12
Identities = 64/250 (25%), Positives = 108/250 (43%), Gaps = 36/250 (14%)
Frame = +3
Query: 171 FKYGANKPLIYDNIDFGVDLDTRVALVGPNGAGKSTLLK--------------------- 287
F A+ ++ N D + R LVGPNG GK+TLLK
Sbjct: 309 FSISAHGKELFVNADLYIVAGRRYGLVGPNGKGKTTLLKHIANRALSIPPNIDVLLCEQE 368
Query: 288 LIASELEPTDGLIRRHSK-CRIGRYHQHLHEILDL-NSTALEWMMKSFPHIKE------K 443
++A E ++R +K ++ + L L+ + TA E + K + ++ +
Sbjct: 369 VVADETPAVQAVLRADTKRLKLLEEERRLQGQLEQGDDTAAERLEKVYEELRATGAAAAE 428
Query: 444 DEMRKKLGRYGLTGGQQICPIKSLSDGQRCRIIFAWLAEGCPHMLLLDEPTNHLDLETID 623
+ R+ L G Q P + S G R R+ A P +L+LDEPTNHLDL +
Sbjct: 429 AKARRILAGLGFDPEMQNRPTQKFSGGWRMRVSLARALFMEPTLLMLDEPTNHLDLNAVI 488
Query: 624 SLADAINEFEGGLLLVSHDFRLIGRVAEEIWVCDHGAVTKWPGDIYSYK-------TSLI 782
L + + + LL+VSHD + V +I D + + G+ ++K L+
Sbjct: 489 WLNNYLQGWRKTLLIVSHDQGFLDDVCTDIIHLDAQRLHYYRGNYMTFKKMYQQKQKELL 548
Query: 783 KEIEREHTRM 812
K+ E++ ++
Sbjct: 549 KQYEKQEKKL 558
>sp|Q7YR37|ABCF1_PANTR ATP-binding cassette sub-family F member 1 (ATP-binding cassette 50)
Length = 807
Score = 187 bits (474), Expect = 4e-47
Identities = 96/233 (41%), Positives = 152/233 (65%)
Frame = +3
Query: 93 REKNLVFSFPSCGEIPPPVIQVQNVSFKYGANKPLIYDNIDFGVDLDTRVALVGPNGAGK 272
+E + F+FP + PPV+ + V+F Y KPL + N+DFG+D+D+R+ +VGPNG GK
Sbjct: 568 KEYTVRFTFPDPPPLSPPVLGLHGVTFGYEGQKPL-FKNLDFGIDMDSRICIVGPNGVGK 626
Query: 273 STLLKLIASELEPTDGLIRRHSKCRIGRYHQHLHEILDLNSTALEWMMKSFPHIKEKDEM 452
STLL L+ +L PT G +R++ + +IG ++Q E L + T E++ + F ++ +D
Sbjct: 627 STLLLLLTGKLTPTHGEMRKNHRLKIGFFNQQYAEQLRMEETPTEYLQRGF-NLPYQDA- 684
Query: 453 RKKLGRYGLTGGQQICPIKSLSDGQRCRIIFAWLAEGCPHMLLLDEPTNHLDLETIDSLA 632
RK LGR+GL I LS GQ+ R++FA LA P +L+LDEPTN+LD+E+ID+L
Sbjct: 685 RKCLGRFGLESHAHTIQICKLSGGQKARVVFAELACREPDVLILDEPTNNLDIESIDALG 744
Query: 633 DAINEFEGGLLLVSHDFRLIGRVAEEIWVCDHGAVTKWPGDIYSYKTSLIKEI 791
+AINE++G +++VSHD RLI ++WV + +V++ GD YK +++ +
Sbjct: 745 EAINEYKGAVIVVSHDARLITETNCQLWVVEEQSVSQIDGDFEDYKREVLEAL 797
Score = 70.9 bits (172), Expect = 5e-12
Identities = 64/250 (25%), Positives = 108/250 (43%), Gaps = 36/250 (14%)
Frame = +3
Query: 171 FKYGANKPLIYDNIDFGVDLDTRVALVGPNGAGKSTLLK--------------------- 287
F A+ ++ N D + R LVGPNG GK+TLLK
Sbjct: 271 FSISAHGKELFVNADLYIVASRRYGLVGPNGKGKTTLLKHIANRALSIPPNIDVLLCEQE 330
Query: 288 LIASELEPTDGLIRRHSK-CRIGRYHQHLHEILDL-NSTALEWMMKSFPHIKE------K 443
++A E ++R +K ++ + L L+ + TA E + K + ++ +
Sbjct: 331 VVADETPAVQAVLRADTKRLKLLEEERRLQGQLEQGDDTAAERLEKVYEELRATGAAAAE 390
Query: 444 DEMRKKLGRYGLTGGQQICPIKSLSDGQRCRIIFAWLAEGCPHMLLLDEPTNHLDLETID 623
+ R+ L G Q P + S G R R+ A P +L+LDEPTNHLDL +
Sbjct: 391 AKARRILAGLGFDPEMQNRPTQKFSGGWRMRVSLARALFMEPTLLMLDEPTNHLDLNAVI 450
Query: 624 SLADAINEFEGGLLLVSHDFRLIGRVAEEIWVCDHGAVTKWPGDIYSYK-------TSLI 782
L + + + LL+VSHD + V +I D + + G+ ++K L+
Sbjct: 451 WLNNYLQGWRKTLLIVSHDQGFLDDVCTDIIHLDAQRLHYYRGNYMTFKKMYQQKQKELL 510
Query: 783 KEIEREHTRM 812
K+ E++ ++
Sbjct: 511 KQYEKQEKKL 520
>sp|Q767L0|ABCF1_PIG ATP-binding cassette sub-family F member 1
Length = 807
Score = 186 bits (472), Expect = 7e-47
Identities = 96/233 (41%), Positives = 152/233 (65%)
Frame = +3
Query: 93 REKNLVFSFPSCGEIPPPVIQVQNVSFKYGANKPLIYDNIDFGVDLDTRVALVGPNGAGK 272
+E + F+FP + PPV+ + V+F Y KPL + N+DFG+D+D+R+ +VGPNG GK
Sbjct: 568 KEYTVRFTFPDPPPLSPPVLGLHGVTFGYEGQKPL-FKNLDFGIDMDSRICIVGPNGVGK 626
Query: 273 STLLKLIASELEPTDGLIRRHSKCRIGRYHQHLHEILDLNSTALEWMMKSFPHIKEKDEM 452
STLL L+ +L PT G +R++ + +IG ++Q E L + T E++ + F ++ +D
Sbjct: 627 STLLLLLTGKLTPTRGEMRKNHRLKIGFFNQQYAEQLRMEETPTEYLQRGF-NLPYQDA- 684
Query: 453 RKKLGRYGLTGGQQICPIKSLSDGQRCRIIFAWLAEGCPHMLLLDEPTNHLDLETIDSLA 632
RK LGR+GL I LS GQ+ R++FA LA P +L+LDEPTN+LD+E+ID+L
Sbjct: 685 RKCLGRFGLESHAHTIQICKLSGGQKARVVFAELACREPDVLILDEPTNNLDIESIDALG 744
Query: 633 DAINEFEGGLLLVSHDFRLIGRVAEEIWVCDHGAVTKWPGDIYSYKTSLIKEI 791
+AINE++G +++VSHD RLI ++WV + +V++ GD YK +++ +
Sbjct: 745 EAINEYKGAVIVVSHDARLITETNCQLWVVEEQSVSQIDGDFDDYKREVLEAL 797
Score = 69.3 bits (168), Expect = 1e-11
Identities = 63/250 (25%), Positives = 108/250 (43%), Gaps = 36/250 (14%)
Frame = +3
Query: 171 FKYGANKPLIYDNIDFGVDLDTRVALVGPNGAGKSTLLK--------------------- 287
F A+ ++ N D + R LVGPNG GK+TLLK
Sbjct: 271 FSISAHGKELFVNADLYIVAGRRYGLVGPNGKGKTTLLKHIANRALSIPPNIDVLLCEQE 330
Query: 288 LIASELEPTDGLIRRHSK-CRIGRYHQHLHEILDL-NSTALEWMMKSFPHIKE------K 443
++A E ++R +K ++ + L L+ + TA + + K + ++ +
Sbjct: 331 VVADETPAVQAVLRADTKRLKLLEEERRLQGQLEQGDDTAADRLEKVYEELRATGAAAAE 390
Query: 444 DEMRKKLGRYGLTGGQQICPIKSLSDGQRCRIIFAWLAEGCPHMLLLDEPTNHLDLETID 623
+ R+ L G Q P + S G R R+ A P +L+LDEPTNHLDL +
Sbjct: 391 AKARRILAGLGFDPEMQNRPTQKFSGGWRMRVSLARALFMEPTLLMLDEPTNHLDLNAVI 450
Query: 624 SLADAINEFEGGLLLVSHDFRLIGRVAEEIWVCDHGAVTKWPGDIYSYK-------TSLI 782
L + + + LL+VSHD + V +I D + + G+ ++K L+
Sbjct: 451 WLNNYLQGWRKTLLIVSHDQGFLDDVCTDIIHLDAQRLHYYRGNYMTFKKMYQQKQKELL 510
Query: 783 KEIEREHTRM 812
K+ E++ ++
Sbjct: 511 KQYEKQEKKL 520
>sp|P63390|YHES_ECO57 Hypothetical ABC transporter ATP-binding protein yheS
sp|P63389|YHES_ECOLI Hypothetical ABC transporter ATP-binding protein yheS
Length = 637
Score = 144 bits (362), Expect = 4e-34
Identities = 86/255 (33%), Positives = 144/255 (56%)
Frame = +3
Query: 6 ARGKLARQAQSKEKTLKKMVDGGLTQKVIREKNLVFSFPSCGEIPPPVIQVQNVSFKYGA 185
A+ A+QAQS+ K L++M L + FSF + +P P+++++ VS YG
Sbjct: 268 AKATKAKQAQSRIKMLERME---LIAPAHVDNPFRFSFRAPESLPNPLLKMEKVSAGYGD 324
Query: 186 NKPLIYDNIDFGVDLDTRVALVGPNGAGKSTLLKLIASELEPTDGLIRRHSKCRIGRYHQ 365
+I D+I + +R+ L+G NGAGKSTL+KL+A EL P G I ++G + Q
Sbjct: 325 R--IILDSIKLNLVPGSRIGLLGRNGAGKSTLIKLLAGELAPVSGEIGLAKGIKLGYFAQ 382
Query: 366 HLHEILDLNSTALEWMMKSFPHIKEKDEMRKKLGRYGLTGGQQICPIKSLSDGQRCRIIF 545
H E L + + ++ + + P E+ ++R LG +G G + + S G++ R++
Sbjct: 383 HQLEYLRADESPIQHLARLAPQELEQ-KLRDYLGGFGFQGDKVTEETRRFSGGEKARLVL 441
Query: 546 AWLAEGCPHMLLLDEPTNHLDLETIDSLADAINEFEGGLLLVSHDFRLIGRVAEEIWVCD 725
A + P++LLLDEPTNHLDL+ +L +A+ EFEG L++VSHD L+ +++++
Sbjct: 442 ALIVWQRPNLLLLDEPTNHLDLDMRQALTEALIEFEGALVVVSHDRHLLRSTTDDLYLVH 501
Query: 726 HGAVTKWPGDIYSYK 770
V + GD+ Y+
Sbjct: 502 DRKVEPFDGDLEDYQ 516
Score = 67.0 bits (162), Expect = 7e-11
Identities = 54/224 (24%), Positives = 94/224 (41%), Gaps = 32/224 (14%)
Frame = +3
Query: 195 LIYDNIDFGVDLDTRVALVGPNGAGKSTLLKLIASELEPTDGLIRRHSKCRIGRYHQHLH 374
++ DN ++ +V LVG NG GKSTLL L+ +E+ G ++ +Q
Sbjct: 15 VLLDNATATINPGQKVGLVGKNGCGKSTLLALLKNEISADGGSYTFPGSWQLAWVNQ--- 71
Query: 375 EILDLNSTALEWMMKSFPHIKE--------------------------------KDEMRK 458
E L ALE+++ ++ +
Sbjct: 72 ETPALPQAALEYVIDGDREYRQLEAQLHDANERNDGHAIATIHGKLDAIDAWSIRSRAAS 131
Query: 459 KLGRYGLTGGQQICPIKSLSDGQRCRIIFAWLAEGCPHMLLLDEPTNHLDLETIDSLADA 638
L G + Q P+ S G R R+ A +LLLDEPTNHLDL+ + L
Sbjct: 132 LLHGLGFSNEQLERPVSDFSGGWRMRLNLAQALICRSDLLLLDEPTNHLDLDAVIWLEKW 191
Query: 639 INEFEGGLLLVSHDFRLIGRVAEEIWVCDHGAVTKWPGDIYSYK 770
+ ++G L+L+SHD + + ++I + ++ ++ G+ S++
Sbjct: 192 LKSYQGTLILISHDRDFLDPIVDKIIHIEQQSMFEYTGNYSSFE 235
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 98,618,840
Number of Sequences: 369166
Number of extensions: 2019368
Number of successful extensions: 10708
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 8844
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 10193
length of database: 68,354,980
effective HSP length: 110
effective length of database: 48,034,130
effective search space used: 8790245790
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)