Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_017_D05
(531 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q16798|MAON_HUMAN NADP-dependent malic enzyme, mitochond... 181 1e-45
sp|Q8BMF3|MAON_MOUSE NADP-dependent malic enzyme, mitochond... 178 6e-45
sp|Q99KE1|MAOM_MOUSE NAD-dependent malic enzyme, mitochondr... 176 2e-44
sp|P28227|MAOX_ANAPL NADP-dependent malic enzyme (NADP-ME) 176 2e-44
sp|P23368|MAOM_HUMAN NAD-dependent malic enzyme, mitochondr... 175 5e-44
sp|P34105|MAOX_POPTR NADP-dependent malic enzyme (NADP-ME) 175 7e-44
sp|P40927|MAOX_COLLI NADP-dependent malic enzyme (NADP-ME) 171 8e-43
sp|P13697|MAOX_RAT NADP-dependent malic enzyme (NADP-ME) (M... 171 1e-42
sp|P43279|MAOC_ORYSA NADP-dependent malic enzyme, chloropla... 170 2e-42
sp|P12628|MAOX_PHAVU NADP-dependent malic enzyme (NADP-ME) 169 4e-42
>sp|Q16798|MAON_HUMAN NADP-dependent malic enzyme, mitochondrial precursor (NADP-ME)
(Malic enzyme 3)
Length = 604
Score = 181 bits (458), Expect = 1e-45
Identities = 87/177 (49%), Positives = 125/177 (70%), Gaps = 1/177 (0%)
Frame = +2
Query: 2 LAEAVKEIKPTVMIGAAGVRGVFTPHILSMLTTFTDRPIVCALSNPTSKSECTAIDAYTH 181
L E V+ +KPT +IG A + G FT IL + +F +RPI+ ALSNPTSK+ECTA Y
Sbjct: 399 LEEVVRLVKPTAIIGVAAIAGAFTEQILRDMASFHERPIIFALSNPTSKAECTAEKCYRV 458
Query: 182 TDGKGIYACGSPFPPVHYKD-KVFIPSQCNNSYIFPGLALAIVMFQIRPVTEDLFFRAAE 358
T+G+GI+A GSPF V +D K FIP Q NN+Y+FPG+AL ++ IR + +++F AE
Sbjct: 459 TEGRGIFASGSPFKSVTLEDGKTFIPGQGNNAYVFPGVALGVIAGGIRHIPDEIFLLTAE 518
Query: 359 TLAKQVSDEDLAQGRVFPALWTIRDVSLEIAVSVAEHAYSTGIAYHRPEPRDKREYI 529
+A++VS++ L+QGR++P L TIRDVSL IA+ V ++AY +A + PEP+DK ++
Sbjct: 519 QIAQEVSEQHLSQGRLYPPLSTIRDVSLRIAIKVLDYAYKHNLASYYPEPKDKEAFV 575
>sp|Q8BMF3|MAON_MOUSE NADP-dependent malic enzyme, mitochondrial precursor (NADP-ME)
(Malic enzyme 3)
Length = 604
Score = 178 bits (452), Expect = 6e-45
Identities = 87/177 (49%), Positives = 124/177 (70%), Gaps = 1/177 (0%)
Frame = +2
Query: 2 LAEAVKEIKPTVMIGAAGVRGVFTPHILSMLTTFTDRPIVCALSNPTSKSECTAIDAYTH 181
L E V+ +KPT +IG A + G FT IL + +F +RPIV ALSNPTSK+ECTA Y
Sbjct: 399 LEEVVRLVKPTAIIGVAAIAGAFTEQILRDMASFHERPIVFALSNPTSKAECTAEKCYRV 458
Query: 182 TDGKGIYACGSPFPPVHYKD-KVFIPSQCNNSYIFPGLALAIVMFQIRPVTEDLFFRAAE 358
T+G+GI+A GSPF V +D + F P Q NN+Y+FPG+AL ++ IR + +++F AE
Sbjct: 459 TEGRGIFASGSPFKSVTLEDGRTFTPGQGNNAYVFPGVALGVIAGGIRHIPDEIFLLTAE 518
Query: 359 TLAKQVSDEDLAQGRVFPALWTIRDVSLEIAVSVAEHAYSTGIAYHRPEPRDKREYI 529
+A++VS++ L+QGR++P L TIRDVSL IAV V ++AY +A + PEP+DK ++
Sbjct: 519 QIAQEVSEQHLSQGRLYPPLSTIRDVSLRIAVKVLDYAYKHNLASYYPEPKDKEAFV 575
>sp|Q99KE1|MAOM_MOUSE NAD-dependent malic enzyme, mitochondrial precursor (NAD-ME) (Malic
enzyme 2)
Length = 589
Score = 176 bits (447), Expect = 2e-44
Identities = 81/175 (46%), Positives = 128/175 (73%), Gaps = 1/175 (0%)
Frame = +2
Query: 8 EAVKEIKPTVMIGAAGVRGVFTPHILSMLTTFTDRPIVCALSNPTSKSECTAIDAYTHTD 187
+AV ++KP+V+IG AG +FT ++ + + +RPI+ ALSNPT+++ECTA DAYT T+
Sbjct: 379 DAVNKLKPSVIIGVAGAGPLFTHGVIKAMASINERPIIFALSNPTAQAECTAEDAYTLTE 438
Query: 188 GKGIYACGSPFPPVHYKD-KVFIPSQCNNSYIFPGLALAIVMFQIRPVTEDLFFRAAETL 364
G+ ++A GSPF PV +D +VF P Q NN+YIFPG+ALA+++ + R +++ +F AA+ L
Sbjct: 439 GRCLFASGSPFEPVKLQDGRVFTPGQGNNAYIFPGVALAVILCEARHISDTVFLEAAKAL 498
Query: 365 AKQVSDEDLAQGRVFPALWTIRDVSLEIAVSVAEHAYSTGIAYHRPEPRDKREYI 529
Q++D +LAQGR++P+L I++VS IA+ +AE+ Y+ +A+ PEP DK Y+
Sbjct: 499 TTQLTDAELAQGRLYPSLANIQEVSANIAIKLAEYLYANKMAFRYPEPEDKARYV 553
>sp|P28227|MAOX_ANAPL NADP-dependent malic enzyme (NADP-ME)
Length = 557
Score = 176 bits (447), Expect = 2e-44
Identities = 87/177 (49%), Positives = 121/177 (68%), Gaps = 1/177 (0%)
Frame = +2
Query: 2 LAEAVKEIKPTVMIGAAGVRGVFTPHILSMLTTFTDRPIVCALSNPTSKSECTAIDAYTH 181
L + VK+IKP+V+IG A + G FT IL + F RPI+ ALSNPTSK+ECTA Y +
Sbjct: 353 LEDIVKDIKPSVLIGVAAIGGAFTKEILQDMAAFNKRPIIFALSNPTSKAECTAEQCYKY 412
Query: 182 TDGKGIYACGSPFPPVHYKD-KVFIPSQCNNSYIFPGLALAIVMFQIRPVTEDLFFRAAE 358
T+G+GI+A GSPF PV + K P Q NNSY+FPG+AL ++ ++ + ED+F AE
Sbjct: 413 TEGRGIFASGSPFDPVTLPNGKTLYPGQGNNSYVFPGVALGVIACGLKHIGEDVFLTTAE 472
Query: 359 TLAKQVSDEDLAQGRVFPALWTIRDVSLEIAVSVAEHAYSTGIAYHRPEPRDKREYI 529
+A+QVS+E+L +GR++P L TI+ VSL+IAV +AE AY A P+P+D +I
Sbjct: 473 VIAEQVSEENLQEGRLYPPLVTIQHVSLKIAVRIAEEAYRNNTASTYPQPKDLEAFI 529
>sp|P23368|MAOM_HUMAN NAD-dependent malic enzyme, mitochondrial precursor (NAD-ME) (Malic
enzyme 2)
Length = 584
Score = 175 bits (444), Expect = 5e-44
Identities = 80/175 (45%), Positives = 125/175 (71%), Gaps = 1/175 (0%)
Frame = +2
Query: 8 EAVKEIKPTVMIGAAGVRGVFTPHILSMLTTFTDRPIVCALSNPTSKSECTAIDAYTHTD 187
+AV +KP+ +IG AG +FTP ++ + + +RP++ ALSNPT+++ECTA +AYT T+
Sbjct: 379 DAVNILKPSTIIGVAGAGRLFTPDVIRAMASINERPVIFALSNPTAQAECTAEEAYTLTE 438
Query: 188 GKGIYACGSPFPPVHYKD-KVFIPSQCNNSYIFPGLALAIVMFQIRPVTEDLFFRAAETL 364
G+ ++A GSPF PV D +VF P Q NN YIFPG+ALA+++ R +++ +F AA+ L
Sbjct: 439 GRCLFASGSPFGPVKLTDGRVFTPGQGNNVYIFPGVALAVILCNTRHISDSVFLEAAKAL 498
Query: 365 AKQVSDEDLAQGRVFPALWTIRDVSLEIAVSVAEHAYSTGIAYHRPEPRDKREYI 529
Q++DE+LAQGR++P L I++VS+ IA+ V E+ Y+ +A+ PEP DK +Y+
Sbjct: 499 TSQLTDEELAQGRLYPPLANIQEVSINIAIKVTEYLYANKMAFRYPEPEDKAKYV 553
>sp|P34105|MAOX_POPTR NADP-dependent malic enzyme (NADP-ME)
Length = 591
Score = 175 bits (443), Expect = 7e-44
Identities = 85/171 (49%), Positives = 116/171 (67%)
Frame = +2
Query: 2 LAEAVKEIKPTVMIGAAGVRGVFTPHILSMLTTFTDRPIVCALSNPTSKSECTAIDAYTH 181
L E VK IKP V+IG +GV FT ++ + +F ++P++ ALSNPTS+SECTA +AYT
Sbjct: 403 LLEVVKAIKPIVLIGTSGVGKTFTKEVIEAMASFNEKPLILALSNPTSQSECTAQEAYTW 462
Query: 182 TDGKGIYACGSPFPPVHYKDKVFIPSQCNNSYIFPGLALAIVMFQIRPVTEDLFFRAAET 361
T GK I+A GSPF PV Y+ KVF+P Q NN+YIFPGL L +V+ V +D+ AAE
Sbjct: 463 TKGKAIFASGSPFDPVEYEGKVFVPGQSNNAYIFPGLGLGLVISGAIRVHDDMLLAAAEA 522
Query: 362 LAKQVSDEDLAQGRVFPALWTIRDVSLEIAVSVAEHAYSTGIAYHRPEPRD 514
LA Q+ +E LA+G ++P L IR +S++IA +VA AY G+A P P +
Sbjct: 523 LAGQIKEEYLAKGLIYPPLSNIRKISVQIAANVAAKAYELGLATRLPRPEN 573
>sp|P40927|MAOX_COLLI NADP-dependent malic enzyme (NADP-ME)
Length = 557
Score = 171 bits (434), Expect = 8e-43
Identities = 84/177 (47%), Positives = 119/177 (67%), Gaps = 1/177 (0%)
Frame = +2
Query: 2 LAEAVKEIKPTVMIGAAGVRGVFTPHILSMLTTFTDRPIVCALSNPTSKSECTAIDAYTH 181
L + VK+IKPTV+IG A + G FT IL + F RPI+ ALSNPTSK+ECTA Y +
Sbjct: 353 LEDIVKDIKPTVLIGVAAIGGAFTQQILQDMAAFNKRPIIFALSNPTSKAECTAEQLYKY 412
Query: 182 TDGKGIYACGSPFPPVHY-KDKVFIPSQCNNSYIFPGLALAIVMFQIRPVTEDLFFRAAE 358
T+G+GI+A GSPF PV + P Q NNSY+FPG+AL ++ ++ + +D+F AE
Sbjct: 413 TEGRGIFASGSPFDPVTLPSGQTLYPGQGNNSYVFPGVALGVISCGLKHIGDDVFLTTAE 472
Query: 359 TLAKQVSDEDLAQGRVFPALWTIRDVSLEIAVSVAEHAYSTGIAYHRPEPRDKREYI 529
+A++VS+E+L +GR++P L TI+ VSL+IAV +A+ AY A P+P D +I
Sbjct: 473 VIAQEVSEENLQEGRLYPPLVTIQQVSLKIAVRIAKEAYRNNTASTYPQPEDLEAFI 529
>sp|P13697|MAOX_RAT NADP-dependent malic enzyme (NADP-ME) (Malic enzyme 1)
Length = 572
Score = 171 bits (432), Expect = 1e-42
Identities = 84/177 (47%), Positives = 119/177 (67%), Gaps = 1/177 (0%)
Frame = +2
Query: 2 LAEAVKEIKPTVMIGAAGVRGVFTPHILSMLTTFTDRPIVCALSNPTSKSECTAIDAYTH 181
L V++IKPT +IG A + G FT IL + F +RPI+ ALSNPTSK+EC+A + Y
Sbjct: 364 LEAIVQKIKPTALIGVAAIGGAFTEQILKDMAAFNERPIIFALSNPTSKAECSAEECYKV 423
Query: 182 TDGKGIYACGSPFPPVHYKD-KVFIPSQCNNSYIFPGLALAIVMFQIRPVTEDLFFRAAE 358
T G+ I+A GSPF PV D + P Q NNSY+FPG+AL +V +R + + +F AE
Sbjct: 424 TKGRAIFASGSPFDPVTLPDGRTLFPGQGNNSYVFPGVALGVVACGLRHINDSVFLTTAE 483
Query: 359 TLAKQVSDEDLAQGRVFPALWTIRDVSLEIAVSVAEHAYSTGIAYHRPEPRDKREYI 529
+++QVSD+ L +GR++P L TIRDVSL+IAV + + AY +A PEP++K E++
Sbjct: 484 VISQQVSDKHLEEGRLYPPLNTIRDVSLKIAVKIVQDAYKEKMATVYPEPQNKEEFV 540
>sp|P43279|MAOC_ORYSA NADP-dependent malic enzyme, chloroplast precursor (NADP-ME)
Length = 638
Score = 170 bits (430), Expect = 2e-42
Identities = 79/175 (45%), Positives = 113/175 (64%)
Frame = +2
Query: 2 LAEAVKEIKPTVMIGAAGVRGVFTPHILSMLTTFTDRPIVCALSNPTSKSECTAIDAYTH 181
L +AV+ IKPTV+IG +GV FT ++ + +F +RP++ +L+NPTS SECTA +AY
Sbjct: 450 LLDAVQSIKPTVLIGTSGVGKTFTKEVIEAMASFNERPVIFSLANPTSHSECTAEEAYNW 509
Query: 182 TDGKGIYACGSPFPPVHYKDKVFIPSQCNNSYIFPGLALAIVMFQIRPVTEDLFFRAAET 361
+ G+ ++A GSPF PV Y K+ +P Q NN+YIFPG L +V+ V ED+ A+ET
Sbjct: 510 SQGRAVFASGSPFDPVEYNGKIHVPGQSNNAYIFPGFGLGVVISGAVRVHEDMLLAASET 569
Query: 362 LAKQVSDEDLAQGRVFPALWTIRDVSLEIAVSVAEHAYSTGIAYHRPEPRDKREY 526
LA Q + E+ +G +FP IR +S IA +VA AY G+A P+PRD +Y
Sbjct: 570 LADQATQENFEKGSIFPPFTNIRKISARIAATVAAKAYELGLATRLPQPRDLEKY 624
>sp|P12628|MAOX_PHAVU NADP-dependent malic enzyme (NADP-ME)
Length = 589
Score = 169 bits (428), Expect = 4e-42
Identities = 80/175 (45%), Positives = 115/175 (65%)
Frame = +2
Query: 2 LAEAVKEIKPTVMIGAAGVRGVFTPHILSMLTTFTDRPIVCALSNPTSKSECTAIDAYTH 181
L EAVK IKPTV+IG++G FT ++ + + ++P++ ALSNPTS+SECTA +AYT
Sbjct: 401 LLEAVKAIKPTVLIGSSGAGKTFTKEVVETMASLNEKPLILALSNPTSQSECTAEEAYTW 460
Query: 182 TDGKGIYACGSPFPPVHYKDKVFIPSQCNNSYIFPGLALAIVMFQIRPVTEDLFFRAAET 361
+ G+ I+A GSPF PV Y+ K+F+P Q NN+YIFPG L ++M V +++ A+E
Sbjct: 461 SKGRAIFASGSPFDPVEYEGKLFVPGQANNAYIFPGFGLGLIMSGAIRVRDEMLLAASEA 520
Query: 362 LAKQVSDEDLAQGRVFPALWTIRDVSLEIAVSVAEHAYSTGIAYHRPEPRDKREY 526
LA QVS+E+ +G ++P IR +S IA VA AY G+A H P+D +Y
Sbjct: 521 LAAQVSEENYDKGLIYPPFTNIRKISANIAAKVAAKAYDLGLASHLKRPKDLVKY 575
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 59,386,368
Number of Sequences: 369166
Number of extensions: 1171769
Number of successful extensions: 3076
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 2984
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3054
length of database: 68,354,980
effective HSP length: 103
effective length of database: 49,327,275
effective search space used: 3600891075
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)