Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_017_C23
(581 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P60842|IF4A1_HUMAN Eukaryotic initiation factor 4A-I (eI... 250 2e-66
sp|P47943|IF4A_SCHPO Eukaryotic initiation factor 4A (eIF4A... 250 2e-66
sp|Q5R5F5|IF4A1_PONPY Eukaryotic initiation factor 4A-I (eI... 250 2e-66
sp|P29562|IF4A1_RABIT Eukaryotic initiation factor 4A-I (eI... 250 2e-66
sp|Q4R8K5|IF4A1_MACFA Eukaryotic initiation factor 4A-I (eI... 248 6e-66
sp|P10630|IF4A2_MOUSE Eukaryotic initiation factor 4A-II (e... 248 8e-66
sp|Q4R4Y9|IF4A2_MACFA Eukaryotic initiation factor 4A-II (e... 248 8e-66
sp|Q02748|IF4A_DROME Eukaryotic initiation factor 4A (eIF4A... 241 1e-63
sp|P27639|IF4A_CAEEL Eukaryotic initiation factor 4A (eIF4A... 239 3e-63
sp|P38919|DDX48_HUMAN Probable ATP-dependent helicase DDX48... 236 3e-62
>sp|P60842|IF4A1_HUMAN Eukaryotic initiation factor 4A-I (eIF4A-I) (eIF-4A-I)
sp|P60843|IF4A1_MOUSE Eukaryotic initiation factor 4A-I (eIF4A-I) (eIF-4A-I)
Length = 406
Score = 250 bits (638), Expect = 2e-66
Identities = 125/173 (72%), Positives = 145/173 (83%)
Frame = +1
Query: 1 ILVKKEELTLEGIRQFYVNVSEEDYKFETLTDLYETLTITQAVIFCNTRRKVDYLTESLK 180
ILVKKEELTLEGIRQFY+NV E++K +TL DLYETLTITQAVIF NTRRKVD+LTE +
Sbjct: 234 ILVKKEELTLEGIRQFYINVEREEWKLDTLCDLYETLTITQAVIFINTRRKVDWLTEKMH 293
Query: 181 AKQFIVSSMHGDMQQDMRDQIMKEFRSGSSRILITTDLLARGIDVQQVSLVINYDLPSNR 360
A+ F VS+MHGDM Q RD IM+EFRSGSSR+LITTDLLARGIDVQQVSLVINYDLP+NR
Sbjct: 294 ARDFTVSAMHGDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNR 353
Query: 361 ENYIHXXXXXXXXXXXXVAINFVTQDDIRTLQDLESYYSTHIEEMPMNIADLI 519
ENYIH VAIN VT++D RTL+D+E++Y+T IEEMP+N+ADLI
Sbjct: 354 ENYIHRIGRGGRFGRKGVAINMVTEEDKRTLRDIETFYNTSIEEMPLNVADLI 406
>sp|P47943|IF4A_SCHPO Eukaryotic initiation factor 4A (eIF4A) (eIF-4A)
Length = 392
Score = 250 bits (638), Expect = 2e-66
Identities = 123/173 (71%), Positives = 144/173 (83%)
Frame = +1
Query: 1 ILVKKEELTLEGIRQFYVNVSEEDYKFETLTDLYETLTITQAVIFCNTRRKVDYLTESLK 180
ILVKK+ELTLEGI+QFYV V +E++K +TL DLYET+T+TQAVIFCNTRRKVD+LTE L
Sbjct: 220 ILVKKDELTLEGIKQFYVAVEKEEWKLDTLCDLYETVTVTQAVIFCNTRRKVDWLTEQLT 279
Query: 181 AKQFIVSSMHGDMQQDMRDQIMKEFRSGSSRILITTDLLARGIDVQQVSLVINYDLPSNR 360
+ F VSSMHGDM Q RD +M EFR+GSSRILITTDLLARGIDVQQVSLVINYDLP+NR
Sbjct: 280 ERDFTVSSMHGDMDQAQRDTLMHEFRTGSSRILITTDLLARGIDVQQVSLVINYDLPANR 339
Query: 361 ENYIHXXXXXXXXXXXXVAINFVTQDDIRTLQDLESYYSTHIEEMPMNIADLI 519
ENYIH V+INFVT DD+R ++++E +Y+THIEEMPMNIADLI
Sbjct: 340 ENYIHRIGRGGRFGRKGVSINFVTNDDVRMMREIEQFYNTHIEEMPMNIADLI 392
>sp|Q5R5F5|IF4A1_PONPY Eukaryotic initiation factor 4A-I (eIF4A-I) (eIF-4A-I)
Length = 406
Score = 250 bits (638), Expect = 2e-66
Identities = 125/173 (72%), Positives = 145/173 (83%)
Frame = +1
Query: 1 ILVKKEELTLEGIRQFYVNVSEEDYKFETLTDLYETLTITQAVIFCNTRRKVDYLTESLK 180
ILVKKEELTLEGIRQFY+NV E++K +TL DLYETLTITQAVIF NTRRKVD+LTE +
Sbjct: 234 ILVKKEELTLEGIRQFYINVEREEWKLDTLCDLYETLTITQAVIFINTRRKVDWLTEKMH 293
Query: 181 AKQFIVSSMHGDMQQDMRDQIMKEFRSGSSRILITTDLLARGIDVQQVSLVINYDLPSNR 360
A+ F VS+MHGDM Q RD IM+EFRSGSSR+LITTDLLARGIDVQQVSLVINYDLP+NR
Sbjct: 294 ARDFTVSAMHGDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNR 353
Query: 361 ENYIHXXXXXXXXXXXXVAINFVTQDDIRTLQDLESYYSTHIEEMPMNIADLI 519
ENYIH VAIN VT++D RTL+D+E++Y+T IEEMP+N+ADLI
Sbjct: 354 ENYIHRIGRGGRFGRKGVAINMVTEEDKRTLRDIETFYNTSIEEMPLNVADLI 406
>sp|P29562|IF4A1_RABIT Eukaryotic initiation factor 4A-I (eIF4A-I) (eIF-4A-I)
Length = 398
Score = 250 bits (638), Expect = 2e-66
Identities = 125/173 (72%), Positives = 145/173 (83%)
Frame = +1
Query: 1 ILVKKEELTLEGIRQFYVNVSEEDYKFETLTDLYETLTITQAVIFCNTRRKVDYLTESLK 180
ILVKKEELTLEGIRQFY+NV E++K +TL DLYETLTITQAVIF NTRRKVD+LTE +
Sbjct: 226 ILVKKEELTLEGIRQFYINVEREEWKLDTLCDLYETLTITQAVIFINTRRKVDWLTEKMH 285
Query: 181 AKQFIVSSMHGDMQQDMRDQIMKEFRSGSSRILITTDLLARGIDVQQVSLVINYDLPSNR 360
A+ F VS+MHGDM Q RD IM+EFRSGSSR+LITTDLLARGIDVQQVSLVINYDLP+NR
Sbjct: 286 ARDFTVSAMHGDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNR 345
Query: 361 ENYIHXXXXXXXXXXXXVAINFVTQDDIRTLQDLESYYSTHIEEMPMNIADLI 519
ENYIH VAIN VT++D RTL+D+E++Y+T IEEMP+N+ADLI
Sbjct: 346 ENYIHRIGRGGRFGRKGVAINMVTEEDKRTLRDIETFYNTSIEEMPLNVADLI 398
>sp|Q4R8K5|IF4A1_MACFA Eukaryotic initiation factor 4A-I (eIF4A-I) (eIF-4A-I)
Length = 406
Score = 248 bits (634), Expect = 6e-66
Identities = 124/173 (71%), Positives = 144/173 (83%)
Frame = +1
Query: 1 ILVKKEELTLEGIRQFYVNVSEEDYKFETLTDLYETLTITQAVIFCNTRRKVDYLTESLK 180
ILVKKEELTLEGIRQFY+NV E++K +TL DLYETLTITQAVIF NTRRKVD+LTE +
Sbjct: 234 ILVKKEELTLEGIRQFYINVEREEWKLDTLCDLYETLTITQAVIFINTRRKVDWLTEKMH 293
Query: 181 AKQFIVSSMHGDMQQDMRDQIMKEFRSGSSRILITTDLLARGIDVQQVSLVINYDLPSNR 360
A+ F S+MHGDM Q RD IM+EFRSGSSR+LITTDLLARGIDVQQVSLVINYDLP+NR
Sbjct: 294 ARDFTASAMHGDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNR 353
Query: 361 ENYIHXXXXXXXXXXXXVAINFVTQDDIRTLQDLESYYSTHIEEMPMNIADLI 519
ENYIH VAIN VT++D RTL+D+E++Y+T IEEMP+N+ADLI
Sbjct: 354 ENYIHRIGRGGRFGRKGVAINMVTEEDKRTLRDIETFYNTSIEEMPLNVADLI 406
>sp|P10630|IF4A2_MOUSE Eukaryotic initiation factor 4A-II (eIF4A-II) (eIF-4A-II)
sp|Q14240|IF4A2_HUMAN Eukaryotic initiation factor 4A-II (eIF4A-II) (eIF-4A-II)
sp|Q5R4X1|IF4A2_PONPY Eukaryotic initiation factor 4A-II (eIF4A-II) (eIF-4A-II)
Length = 407
Score = 248 bits (633), Expect = 8e-66
Identities = 123/173 (71%), Positives = 145/173 (83%)
Frame = +1
Query: 1 ILVKKEELTLEGIRQFYVNVSEEDYKFETLTDLYETLTITQAVIFCNTRRKVDYLTESLK 180
ILVKKEELTLEGI+QFY+NV E++K +TL DLYETLTITQAVIF NTRRKVD+LTE +
Sbjct: 235 ILVKKEELTLEGIKQFYINVEREEWKLDTLCDLYETLTITQAVIFLNTRRKVDWLTEKMH 294
Query: 181 AKQFIVSSMHGDMQQDMRDQIMKEFRSGSSRILITTDLLARGIDVQQVSLVINYDLPSNR 360
A+ F VS++HGDM Q RD IM+EFRSGSSR+LITTDLLARGIDVQQVSLVINYDLP+NR
Sbjct: 295 ARDFTVSALHGDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNR 354
Query: 361 ENYIHXXXXXXXXXXXXVAINFVTQDDIRTLQDLESYYSTHIEEMPMNIADLI 519
ENYIH VAINFVT++D R L+D+E++Y+T +EEMPMN+ADLI
Sbjct: 355 ENYIHRIGRGGRFGRKGVAINFVTEEDKRILRDIETFYNTTVEEMPMNVADLI 407
>sp|Q4R4Y9|IF4A2_MACFA Eukaryotic initiation factor 4A-II (eIF4A-II) (eIF-4A-II)
Length = 408
Score = 248 bits (633), Expect = 8e-66
Identities = 123/173 (71%), Positives = 145/173 (83%)
Frame = +1
Query: 1 ILVKKEELTLEGIRQFYVNVSEEDYKFETLTDLYETLTITQAVIFCNTRRKVDYLTESLK 180
ILVKKEELTLEGI+QFY+NV E++K +TL DLYETLTITQAVIF NTRRKVD+LTE +
Sbjct: 236 ILVKKEELTLEGIKQFYINVEREEWKLDTLCDLYETLTITQAVIFLNTRRKVDWLTEKMH 295
Query: 181 AKQFIVSSMHGDMQQDMRDQIMKEFRSGSSRILITTDLLARGIDVQQVSLVINYDLPSNR 360
A+ F VS++HGDM Q RD IM+EFRSGSSR+LITTDLLARGIDVQQVSLVINYDLP+NR
Sbjct: 296 ARDFTVSALHGDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNR 355
Query: 361 ENYIHXXXXXXXXXXXXVAINFVTQDDIRTLQDLESYYSTHIEEMPMNIADLI 519
ENYIH VAINFVT++D R L+D+E++Y+T +EEMPMN+ADLI
Sbjct: 356 ENYIHRIGRGGRFGRKGVAINFVTEEDKRILRDIETFYNTTVEEMPMNVADLI 408
>sp|Q02748|IF4A_DROME Eukaryotic initiation factor 4A (eIF4A) (eIF-4A)
Length = 403
Score = 241 bits (614), Expect = 1e-63
Identities = 122/173 (70%), Positives = 140/173 (80%)
Frame = +1
Query: 1 ILVKKEELTLEGIRQFYVNVSEEDYKFETLTDLYETLTITQAVIFCNTRRKVDYLTESLK 180
ILVKKEELTLEGI+QFYVNV +E++K TL DLY+TL+ITQ+VIFCNTRRKVD LT+ +
Sbjct: 231 ILVKKEELTLEGIKQFYVNVKQENWKLGTLCDLYDTLSITQSVIFCNTRRKVDQLTQEMS 290
Query: 181 AKQFIVSSMHGDMQQDMRDQIMKEFRSGSSRILITTDLLARGIDVQQVSLVINYDLPSNR 360
F VS+MHGDM+Q R+ IMK+FRSGSSR+LITTDLLARGIDVQQVSLVINYDLPSNR
Sbjct: 291 IHNFTVSAMHGDMEQRDREVIMKQFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPSNR 350
Query: 361 ENYIHXXXXXXXXXXXXVAINFVTQDDIRTLQDLESYYSTHIEEMPMNIADLI 519
ENYIH VAINF+T DD R L+D+E +Y T IEEMP NIADLI
Sbjct: 351 ENYIHRIGRGGRFGRKGVAINFITDDDRRILKDIEQFYHTTIEEMPANIADLI 403
>sp|P27639|IF4A_CAEEL Eukaryotic initiation factor 4A (eIF4A) (eIF-4A)
Length = 402
Score = 239 bits (611), Expect = 3e-63
Identities = 119/173 (68%), Positives = 140/173 (80%)
Frame = +1
Query: 1 ILVKKEELTLEGIRQFYVNVSEEDYKFETLTDLYETLTITQAVIFCNTRRKVDYLTESLK 180
ILVKK+ELTLEGIRQFY+NV ++++KF+ L DLY + +TQAVIFCNTRRKVD LTE +
Sbjct: 230 ILVKKDELTLEGIRQFYINVQKDEWKFDCLCDLYNVVNVTQAVIFCNTRRKVDTLTEKMT 289
Query: 181 AKQFIVSSMHGDMQQDMRDQIMKEFRSGSSRILITTDLLARGIDVQQVSLVINYDLPSNR 360
QF VS +HGDM Q RD IM+EFRSGSSR+LITTD+LARGIDVQQVSLVINYDLPSNR
Sbjct: 290 ENQFTVSCLHGDMDQAERDTIMREFRSGSSRVLITTDILARGIDVQQVSLVINYDLPSNR 349
Query: 361 ENYIHXXXXXXXXXXXXVAINFVTQDDIRTLQDLESYYSTHIEEMPMNIADLI 519
ENYIH VAINFVT++D R L+++ESYY+T IEEMP +IADLI
Sbjct: 350 ENYIHRIGRSGRFGRKGVAINFVTENDARQLKEIESYYTTQIEEMPESIADLI 402
>sp|P38919|DDX48_HUMAN Probable ATP-dependent helicase DDX48 (DEAD-box protein 48)
(Eukaryotic initiation factor 4A-like NUK-34) (Nuclear
matrix protein 265) (hNMP 265) (Eukaryotic translation
initiation factor 4A isoform 3)
Length = 411
Score = 236 bits (602), Expect = 3e-62
Identities = 116/173 (67%), Positives = 140/173 (80%)
Frame = +1
Query: 1 ILVKKEELTLEGIRQFYVNVSEEDYKFETLTDLYETLTITQAVIFCNTRRKVDYLTESLK 180
ILVK++ELTLEGI+QF+V V E++KF+TL DLY+TLTITQAVIFCNT+RKVD+LTE ++
Sbjct: 239 ILVKRDELTLEGIKQFFVAVEREEWKFDTLCDLYDTLTITQAVIFCNTKRKVDWLTEKMR 298
Query: 181 AKQFIVSSMHGDMQQDMRDQIMKEFRSGSSRILITTDLLARGIDVQQVSLVINYDLPSNR 360
F VSSMHGDM Q R+ IMKEFRSG+SR+LI+TD+ ARG+DV QVSL+INYDLP+NR
Sbjct: 299 EANFTVSSMHGDMPQKERESIMKEFRSGASRVLISTDVWARGLDVPQVSLIINYDLPNNR 358
Query: 361 ENYIHXXXXXXXXXXXXVAINFVTQDDIRTLQDLESYYSTHIEEMPMNIADLI 519
E YIH VAINFV DDIR L+D+E YYST I+EMPMN+ADLI
Sbjct: 359 ELYIHRIGRSGRYGRKGVAINFVKNDDIRILRDIEQYYSTQIDEMPMNVADLI 411
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 55,566,134
Number of Sequences: 369166
Number of extensions: 957875
Number of successful extensions: 2619
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 2552
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 2584
length of database: 68,354,980
effective HSP length: 105
effective length of database: 48,957,805
effective search space used: 4308286840
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)