Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_017_C15
(942 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P33435|MMP13_MOUSE Collagenase 3 precursor (Matrix metal... 71 4e-12
sp|O62806|MMP13_RABIT Collagenase 3 precursor (Matrix metal... 69 2e-11
sp|P45452|MMP13_HUMAN Collagenase 3 precursor (Matrix metal... 68 4e-11
sp|P23097|MMP13_RAT Collagenase 3 precursor (Matrix metallo... 68 4e-11
sp|O18927|MMP13_HORSE Collagenase 3 precursor (Matrix metal... 68 4e-11
sp|P53690|MMP14_MOUSE Matrix metalloproteinase-14 precursor... 67 6e-11
sp|P51512|MMP16_HUMAN Matrix metalloproteinase-16 precursor... 67 7e-11
sp|Q9XT90|MMP14_PIG Matrix metalloproteinase-14 precursor (... 67 7e-11
sp|Q9R0S2|MMP24_MOUSE Matrix metalloproteinase-24 precursor... 67 7e-11
sp|Q99PW6|MMP24_RAT Matrix metalloproteinase-24 precursor (... 67 7e-11
>sp|P33435|MMP13_MOUSE Collagenase 3 precursor (Matrix metalloproteinase-13) (MMP-13)
Length = 472
Score = 71.2 bits (173), Expect = 4e-12
Identities = 60/191 (31%), Positives = 91/191 (47%), Gaps = 4/191 (2%)
Frame = +1
Query: 1 VAAHEMGHAIGLFHSNDPNALMAPWYGGYISENDFKLPDDDSQGAAFIYGTKNGKVFVRS 180
VAAHE+GH++GL HS DP ALM P Y Y ++ F LPDDD QG F+YG + +
Sbjct: 220 VAAHELGHSLGLDHSKDPGALMFPIY-TYTGKSHFMLPDDDVQGIQFLYGPGDEDPNPKH 278
Query: 181 NKKREQSANEKELCNITNINSAFQYSDDNIYVVTDKNKVFRIIHSNNSFRVDASFKTLQL 360
K E+ L IT++ D + +V + SF +L
Sbjct: 279 PKTPEKCDPALSLDAITSLRGETMIFKDRFFWRLHPQQVEAELFLTKSF-------WPEL 331
Query: 361 PNQLFDSDALFYDYSGRRFVF-FKGNRVFSANGVKLEN---LTISELNVTRPGGFQGRVT 528
PN + DA Y++ R +F F+G + ++ NG + IS+L + R++
Sbjct: 332 PNHV---DAA-YEHPSRDLMFIFRGRKFWALNGYDILEGYPRKISDLGFPKE---VKRLS 384
Query: 529 AAIVRDKTGKS 561
AA+ + TGK+
Sbjct: 385 AAVHFENTGKT 395
>sp|O62806|MMP13_RABIT Collagenase 3 precursor (Matrix metalloproteinase-13) (MMP-13)
Length = 471
Score = 68.9 bits (167), Expect = 2e-11
Identities = 58/191 (30%), Positives = 90/191 (47%), Gaps = 4/191 (2%)
Frame = +1
Query: 1 VAAHEMGHAIGLFHSNDPNALMAPWYGGYISENDFKLPDDDSQGAAFIYGTKNGKVFVRS 180
VAAHE GH++GL HS DP ALM P Y Y ++ F LPDDD QG +YG + +
Sbjct: 219 VAAHEFGHSLGLDHSKDPGALMFPIY-TYTGKSHFMLPDDDVQGIQSLYGPGDEDPNPKH 277
Query: 181 NKKREQSANEKELCNITNINSAFQYSDDNIYVVTDKNKVFRIIHSNNSFRVDASFKTLQL 360
K ++ L IT++ D + +V + SF +L
Sbjct: 278 PKTPDKCDPSLSLDAITSLRGETMIFKDRFFWRLHPQQVDAELFLTKSF-------WPEL 330
Query: 361 PNQLFDSDALFYDYSGRRFVF-FKGNRVFSANGVKLEN---LTISELNVTRPGGFQGRVT 528
PN++ DA Y++ R +F F+G + ++ NG + +SEL R +++
Sbjct: 331 PNRI---DAA-YEHPARDLIFIFRGKKFWAPNGYDILEGYPQKLSELGFpre---VKKIS 383
Query: 529 AAIVRDKTGKS 561
AA+ + TGK+
Sbjct: 384 AAVHFEDTGKT 394
>sp|P45452|MMP13_HUMAN Collagenase 3 precursor (Matrix metalloproteinase-13) (MMP-13)
Length = 471
Score = 67.8 bits (164), Expect = 4e-11
Identities = 56/190 (29%), Positives = 87/190 (45%), Gaps = 3/190 (1%)
Frame = +1
Query: 1 VAAHEMGHAIGLFHSNDPNALMAPWYGGYISENDFKLPDDDSQGAAFIYGTKNGKVFVRS 180
VAAHE GH++GL HS DP ALM P Y Y ++ F LPDDD QG +YG + +
Sbjct: 219 VAAHEFGHSLGLDHSKDPGALMFPIY-TYTGKSHFMLPDDDVQGIQSLYGPGDEDPNPKH 277
Query: 181 NKKREQSANEKELCNITNINSAFQYSDDNIYVVTDKNKVFRIIHSNNSFRVDASFKTLQL 360
K ++ L IT++ D + +V + SF +L
Sbjct: 278 PKTPDKCDPSLSLDAITSLRGETMIFKDRFFWRLHPQQVDAELFLTKSF-------WPEL 330
Query: 361 PNQLFDSDALFYDYSGRRFVFFKGNRVFSANGVKLEN---LTISELNVTRPGGFQGRVTA 531
PN++ DA + S F+G + ++ NG + ISEL + + +++A
Sbjct: 331 PNRI---DAAYEHPSHDLIFIFRGRKFWALNGYDILEGYPKKISELGLPKE---VKKISA 384
Query: 532 AIVRDKTGKS 561
A+ + TGK+
Sbjct: 385 AVHFEDTGKT 394
>sp|P23097|MMP13_RAT Collagenase 3 precursor (Matrix metalloproteinase-13) (MMP-13)
(UMRCASE)
Length = 466
Score = 67.8 bits (164), Expect = 4e-11
Identities = 59/191 (30%), Positives = 90/191 (47%), Gaps = 4/191 (2%)
Frame = +1
Query: 1 VAAHEMGHAIGLFHSNDPNALMAPWYGGYISENDFKLPDDDSQGAAFIYGTKNGKVFVRS 180
VAAHE+GH++GL HS DP ALM P Y Y ++ F LPDDD QG +YG + +
Sbjct: 214 VAAHELGHSLGLDHSKDPGALMFPIY-TYTGKSHFMLPDDDVQGIQSLYGPGDEDPNPKH 272
Query: 181 NKKREQSANEKELCNITNINSAFQYSDDNIYVVTDKNKVFRIIHSNNSFRVDASFKTLQL 360
K E+ L IT++ D + +V + SF +L
Sbjct: 273 PKTPEKCDPALSLDAITSLRGETMIFKDRFFWRLHPQQVEPELFLTKSF-------WPEL 325
Query: 361 PNQLFDSDALFYDYSGRRFVF-FKGNRVFSANGVKLEN---LTISELNVTRPGGFQGRVT 528
PN + DA Y++ R +F F+G + ++ NG + IS+L + R++
Sbjct: 326 PNHV---DAA-YEHPSRDLMFIFRGRKFWALNGYDIMEGYPRKISDLGFPKE---VKRLS 378
Query: 529 AAIVRDKTGKS 561
AA+ + TGK+
Sbjct: 379 AAVHFEDTGKT 389
>sp|O18927|MMP13_HORSE Collagenase 3 precursor (Matrix metalloproteinase-13) (MMP-13)
Length = 472
Score = 67.8 bits (164), Expect = 4e-11
Identities = 57/191 (29%), Positives = 90/191 (47%), Gaps = 4/191 (2%)
Frame = +1
Query: 1 VAAHEMGHAIGLFHSNDPNALMAPWYGGYISENDFKLPDDDSQGAAFIYGTKNGKVFVRS 180
VAAHE GH++GL HS DP ALM P Y Y ++ F LPDDD QG ++YG + +
Sbjct: 220 VAAHEFGHSLGLDHSKDPGALMFPIY-TYTGKSHFVLPDDDVQGIQYLYGPGDEDPNPKH 278
Query: 181 NKKREQSANEKELCNITNINSAFQYSDDNIYVVTDKNKVFRIIHSNNSFRVDASFKTLQL 360
K ++ L IT++ D + V + SF +L
Sbjct: 279 PKTPDKCDPSLSLDAITSLRGETMVFKDRFFWRLHPQLVDAELFLTKSF-------WPEL 331
Query: 361 PNQLFDSDALFYDYSGRRFVF-FKGNRVFSANGVKLEN---LTISELNVTRPGGFQGRVT 528
PN++ DA Y++ + +F F+G + ++ NG + ISEL + +++
Sbjct: 332 PNRI---DAA-YEHPSKDLIFIFRGRKFWALNGYDILEGYPQKISELGFPKD---VKKIS 384
Query: 529 AAIVRDKTGKS 561
AA+ + TGK+
Sbjct: 385 AAVHFEDTGKT 395
>sp|P53690|MMP14_MOUSE Matrix metalloproteinase-14 precursor (MMP-14) (Membrane-type
matrix metalloproteinase 1) (MT-MMP 1) (MTMMP1)
(Membrane-type-1 matrix metalloproteinase) (MT1-MMP)
(MT1MMP) (MMP-X1) (MT-MMP)
Length = 582
Score = 67.4 bits (163), Expect = 6e-11
Identities = 31/54 (57%), Positives = 42/54 (77%)
Frame = +1
Query: 1 VAAHEMGHAIGLFHSNDPNALMAPWYGGYISENDFKLPDDDSQGAAFIYGTKNG 162
VA HE+GHA+GL HSNDP+A+M+P+Y +EN F LPDDD +G +YG+K+G
Sbjct: 236 VAVHELGHALGLEHSNDPSAIMSPFYQWMDTEN-FVLPDDDRRGIQQLYGSKSG 288
>sp|P51512|MMP16_HUMAN Matrix metalloproteinase-16 precursor (MMP-16) (Membrane-type
matrix metalloproteinase 3) (MT-MMP 3) (MTMMP3)
(Membrane-type-3 matrix metalloproteinase) (MT3-MMP)
(MT3MMP) (MMP-X2)
Length = 607
Score = 67.0 bits (162), Expect = 7e-11
Identities = 31/50 (62%), Positives = 39/50 (78%)
Frame = +1
Query: 1 VAAHEMGHAIGLFHSNDPNALMAPWYGGYISENDFKLPDDDSQGAAFIYG 150
VA HE+GHA+GL HSNDP A+MAP+Y Y+ ++FKLP+DD QG IYG
Sbjct: 243 VAVHELGHALGLEHSNDPTAIMAPFY-QYMETDNFKLPNDDLQGIQKIYG 291
>sp|Q9XT90|MMP14_PIG Matrix metalloproteinase-14 precursor (MMP-14) (Membrane-type
matrix metalloproteinase 1) (MT-MMP 1) (MTMMP1)
(Membrane-type-1 matrix metalloproteinase) (MT1-MMP)
(MT1MMP)
Length = 580
Score = 67.0 bits (162), Expect = 7e-11
Identities = 31/54 (57%), Positives = 42/54 (77%)
Frame = +1
Query: 1 VAAHEMGHAIGLFHSNDPNALMAPWYGGYISENDFKLPDDDSQGAAFIYGTKNG 162
VA HE+GHA+GL HSNDP+A+MAP+Y +EN F LPDDD +G +YG+++G
Sbjct: 234 VAVHELGHALGLEHSNDPSAIMAPFYQWMDTEN-FVLPDDDRRGIQQLYGSESG 286
>sp|Q9R0S2|MMP24_MOUSE Matrix metalloproteinase-24 precursor (MMP-24) (Membrane-type
matrix metalloproteinase 5) (MT-MMP 5) (Membrane-type-5
matrix metalloproteinase) (MT5-MMP) (MMP-21)
Length = 618
Score = 67.0 bits (162), Expect = 7e-11
Identities = 31/50 (62%), Positives = 39/50 (78%)
Frame = +1
Query: 1 VAAHEMGHAIGLFHSNDPNALMAPWYGGYISENDFKLPDDDSQGAAFIYG 150
VA HE+GHA+GL HSNDP+A+MAP+Y Y+ ++FKLP DD QG IYG
Sbjct: 252 VAVHELGHALGLEHSNDPSAIMAPFY-QYMETHNFKLPQDDLQGIQKIYG 300
>sp|Q99PW6|MMP24_RAT Matrix metalloproteinase-24 precursor (MMP-24) (Membrane-type
matrix metalloproteinase 5) (MT-MMP 5) (Membrane-type-5
matrix metalloproteinase) (MT5-MMP)
Length = 618
Score = 67.0 bits (162), Expect = 7e-11
Identities = 31/50 (62%), Positives = 39/50 (78%)
Frame = +1
Query: 1 VAAHEMGHAIGLFHSNDPNALMAPWYGGYISENDFKLPDDDSQGAAFIYG 150
VA HE+GHA+GL HSNDP+A+MAP+Y Y+ ++FKLP DD QG IYG
Sbjct: 252 VAVHELGHALGLEHSNDPSAIMAPFY-QYMETHNFKLPQDDLQGIQKIYG 300
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 101,974,254
Number of Sequences: 369166
Number of extensions: 2040697
Number of successful extensions: 5692
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 5415
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5645
length of database: 68,354,980
effective HSP length: 110
effective length of database: 48,034,130
effective search space used: 9750928390
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)