Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_016_P19
(888 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P51660|DHB4_MOUSE Peroxisomal multifunctional enzyme typ... 256 8e-68
sp|P97852|DHB4_RAT Peroxisomal multifunctional enzyme type ... 248 1e-65
sp|P51659|DHB4_HUMAN Peroxisomal multifunctional enzyme typ... 246 8e-65
sp|Q01373|FOX2_NEUCR Peroxisomal hydratase-dehydrogenase-ep... 181 3e-45
sp|Q02207|FOX2_YEAST Peroxisomal hydratase-dehydrogenase-ep... 169 7e-42
sp|P22414|FOX2_CANTR Peroxisomal hydratase-dehydrogenase-ep... 160 6e-39
sp|P50203|PHAB_ACISR Acetoacetyl-CoA reductase 65 2e-10
sp|Q93X68|FABG5_BRANA 3-oxoacyl-[acyl-carrier-protein] redu... 64 6e-10
sp|P45375|PHBB_CHRVI Acetoacetyl-CoA reductase 61 5e-09
sp|P73826|FABG2_SYNY3 3-oxoacyl-[acyl-carrier-protein] redu... 61 5e-09
>sp|P51660|DHB4_MOUSE Peroxisomal multifunctional enzyme type 2 (MFE-2) (D-bifunctional
protein) (DBP) (17-beta-hydroxysteroid dehydrogenase 4)
(17-beta-HSD 4) [Includes: D-3-hydroxyacyl-CoA
dehydratase ; 3-hydroxyacyl-CoA dehydrogenase ]
Length = 735
Score = 256 bits (653), Expect = 8e-68
Identities = 139/287 (48%), Positives = 186/287 (64%), Gaps = 3/287 (1%)
Frame = +3
Query: 3 AWNYMRNQKFGRIIFTSSSSGIYGNFGQANYSAAKLGLVGLCNTLAIEGAKYNIKCNTIA 182
AW++M+ Q +GRI+ TSS+SGIYGNFGQANYSAAKLG++GLCNTLAIEG K NI CNTIA
Sbjct: 134 AWDHMKKQNYGRILMTSSASGIYGNFGQANYSAAKLGILGLCNTLAIEGRKNNIHCNTIA 193
Query: 183 PVAGSRLTEDVFPPELYNAFKPEYVSPLVLYLCHPSNINSGNLFEVGAGWIGKVRWEVSR 362
P AGSR+TE V P +L A KPEYV+PLVL+LCH S +G LFEVGAGWIGK+RWE +
Sbjct: 194 PNAGSRMTETVLPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVGAGWIGKLRWERTL 253
Query: 363 GVVLKKKENKFFTVEDVRDQWDEINDFTESRHPTSNKDSIQNFLEVXXXXXXXXXXXXXX 542
G +++K+ N+ T E VRD W++I DF+ + P + ++S +EV
Sbjct: 254 GAIVRKR-NQPMTPEAVRDNWEKICDFSNASKPQTIQESTGGIVEVLHKVDSEGISPNRT 312
Query: 543 XXXXXXXXXXXF--IGKSKTSTYESISFQKAILYAISVGINNSKIENLKFLYENHSNFSV 716
+G S S + ++I+YA+ VG + ++LKF+YE ++FS
Sbjct: 313 SHAAPAATSGFVGAVGHKLPSFSSSYTELQSIMYALGVGASVKNPKDLKFVYEGSADFSC 372
Query: 717 LPTFAVIASFDNVFN-MLNEVMSASDNAFDLSQVLHGEQYLEVYKSL 854
LPTF VI + ++ N L EV S F+ ++ LHGEQYLE+YK L
Sbjct: 373 LPTFGVIVAQKSMMNGGLAEVPGLS---FNFAKALHGEQYLELYKPL 416
>sp|P97852|DHB4_RAT Peroxisomal multifunctional enzyme type 2 (MFE-2) (D-bifunctional
protein) (DBP) (17-beta-hydroxysteroid dehydrogenase 4)
(17-beta-HSD 4) [Includes: D-3-hydroxyacyl-CoA
dehydratase ; 3-hydroxyacyl-CoA dehydrogenase ]
Length = 735
Score = 248 bits (634), Expect = 1e-65
Identities = 139/287 (48%), Positives = 182/287 (63%), Gaps = 3/287 (1%)
Frame = +3
Query: 3 AWNYMRNQKFGRIIFTSSSSGIYGNFGQANYSAAKLGLVGLCNTLAIEGAKYNIKCNTIA 182
AW++M+ Q +GRII T+S+SGIYGNFGQANYSAAKLGL+GL NTL IEG K NI CNTIA
Sbjct: 134 AWDHMKKQNYGRIIMTASASGIYGNFGQANYSAAKLGLLGLANTLVIEGRKNNIHCNTIA 193
Query: 183 PVAGSRLTEDVFPPELYNAFKPEYVSPLVLYLCHPSNINSGNLFEVGAGWIGKVRWEVSR 362
P AGSR+TE V P +L A KPEYV+PLVL+LCH S +G LFEVGAGWIGK+RWE +
Sbjct: 194 PNAGSRMTETVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVGAGWIGKLRWERTL 253
Query: 363 GVVLKKKENKFFTVEDVRDQWDEINDFTESRHPTSNKDSIQNFLEV--XXXXXXXXXXXX 536
G +++K+ N+ T E VRD W +I DF+ + P S ++S +EV
Sbjct: 254 GAIVRKR-NQPMTPEAVRDNWVKICDFSNASKPKSIQESTGGIIEVLHKIDSEGISQNHT 312
Query: 537 XXXXXXXXXXXXXFIGKSKTSTYESISFQKAILYAISVGINNSKIENLKFLYENHSNFSV 716
+G S S + + I+YA+ VG + ++LKF+YE ++FS
Sbjct: 313 GQVASADASGFAGVVGHKLPSFSSSYTELQCIMYALGVGASVKNPKDLKFVYEGSADFSC 372
Query: 717 LPTFAVIASFDNVFN-MLNEVMSASDNAFDLSQVLHGEQYLEVYKSL 854
LPTF VI + ++ + L EV S N ++VLHGEQYLE+YK L
Sbjct: 373 LPTFGVIVAQKSLMSGGLAEVPGLSIN---FAKVLHGEQYLELYKPL 416
>sp|P51659|DHB4_HUMAN Peroxisomal multifunctional enzyme type 2 (MFE-2) (D-bifunctional
protein) (DBP) (17-beta-hydroxysteroid dehydrogenase 4)
(17-beta-HSD 4) [Includes: D-3-hydroxyacyl-CoA
dehydratase ; 3-hydroxyacyl-CoA dehydrogenase ]
Length = 736
Score = 246 bits (627), Expect = 8e-65
Identities = 139/288 (48%), Positives = 181/288 (62%), Gaps = 4/288 (1%)
Frame = +3
Query: 3 AWNYMRNQKFGRIIFTSSSSGIYGNFGQANYSAAKLGLVGLCNTLAIEGAKYNIKCNTIA 182
AW +M+ QK+GRII TSS+SGIYGNFGQANYSAAKLGL+GL N+LAIEG K NI CNTIA
Sbjct: 134 AWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAIEGRKSNIHCNTIA 193
Query: 183 PVAGSRLTEDVFPPELYNAFKPEYVSPLVLYLCHPSNINSGNLFEVGAGWIGKVRWEVSR 362
P AGSR+T+ V P +L A KPEYV+PLVL+LCH S +G LFEVGAGWIGK+RWE +
Sbjct: 194 PNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVGAGWIGKLRWERTL 253
Query: 363 GVVLKKKENKFFTVEDVRDQWDEINDFTESRHPTSNKDSIQNFLEVXXXXXXXXXXXXXX 542
G ++++K N T E V+ W +I DF + P S ++S + +EV
Sbjct: 254 GAIVRQK-NHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLSKIDSEGGVSANH 312
Query: 543 XXXXXXXXXXXF---IGKSKTSTYESISFQKAILYAISVGINNSKIENLKFLYENHSNFS 713
F IG+ + + +AI+YA+ VG + ++LKF+YE S+FS
Sbjct: 313 TSRATSTATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKDLKFIYEGSSDFS 372
Query: 714 VLPTFAVIASFDNVF-NMLNEVMSASDNAFDLSQVLHGEQYLEVYKSL 854
LPTF VI ++ L E+ S N ++VLHGEQYLE+YK L
Sbjct: 373 CLPTFGVIIGQKSMMGGGLAEIPGLSIN---FAKVLHGEQYLELYKPL 417
>sp|Q01373|FOX2_NEUCR Peroxisomal hydratase-dehydrogenase-epimerase (HDE) (Multifunctional
beta-oxidation protein) (MFP) [Includes: 2-enoyl-CoA
hydratase ; D-3-hydroxyacyl CoA dehydrogenase ]
Length = 894
Score = 181 bits (458), Expect = 3e-45
Identities = 110/288 (38%), Positives = 157/288 (54%), Gaps = 6/288 (2%)
Frame = +3
Query: 3 AWNYMRNQKFGRIIFTSSSSGIYGNFGQANYSAAKLGLVGLCNTLAIEGAKYNIKCNTIA 182
AW Y QK+GR++ T+S+SGIYGNFGQANYSAAK ++G +A+EGAKYNI NTIA
Sbjct: 428 AWPYFLKQKYGRVLNTTSTSGIYGNFGQANYSAAKCAILGFSRAIALEGAKYNIYVNTIA 487
Query: 183 PVAGSRLTEDVFPPELYNAFKPEYVSPLVLYLCHPS--NINSGNLFEVGAGWIGKVRWEV 356
P AG+ +T+ + P EL AFKP+YV+PLVL LC +G L+EVG+GW G+ RW+
Sbjct: 488 PNAGTAMTKTILPEELVQAFKPDYVAPLVLALCSDKVPKKPTGGLYEVGSGWCGQTRWQR 547
Query: 357 SRGVVLKKKENKFFTVEDVRDQWDEINDF-TESRHPTSNKDSIQNFLEVXXXXXXXXXXX 533
S G + T E+V W++I F + + HP DSI+ +
Sbjct: 548 SGGHGF--PVDVPLTPEEVVKHWNDIVTFDSRADHPEKASDSIEKIM--ANMENRVGEGK 603
Query: 534 XXXXXXXXXXXXXXFIGKSKTSTYESISFQKAILYAISVGINNSKIENLKFLYENHSNFS 713
F G T + + + LY + +G +K ++K+++E + +F
Sbjct: 604 SGAAENEHLAAIKKFTGVEGKGTEYTFTERDVCLYNLGIG---AKRTDIKYIFEGNEDFE 660
Query: 714 VLPTFAVIASFDNVFNMLNEVMSASDNA---FDLSQVLHGEQYLEVYK 848
V+PTF VI F+ E+ + D+ F +LHGEQYLEV K
Sbjct: 661 VVPTFGVIPPFN------TEMPFSFDDIVPNFSPMMLLHGEQYLEVRK 702
Score = 172 bits (436), Expect = 1e-42
Identities = 84/159 (52%), Positives = 113/159 (71%), Gaps = 1/159 (0%)
Frame = +3
Query: 3 AWNYMRNQKFGRIIFTSSSSGIYGNFGQANYSAAKLGLVGLCNTLAIEGAKYNIKCNTIA 182
AW Y R QKFGR+I T+S++G++GNFGQANYSAAKLG+VG TLA EG KYNI N IA
Sbjct: 134 AWPYFRKQKFGRVINTASAAGLFGNFGQANYSAAKLGMVGFTETLAKEGLKYNIISNVIA 193
Query: 183 PVAGSRLTEDVFPPELYNAFKPEYVSPLVLYLCHPSNIN-SGNLFEVGAGWIGKVRWEVS 359
P+A SR+TE V PP+L KPE+V PLV L H +N + +G++FEVG G + K+RWE S
Sbjct: 194 PIAASRMTETVMPPDLLALMKPEWVVPLVAVLVHKNNTSETGSIFEVGGGHVAKLRWERS 253
Query: 360 RGVVLKKKENKFFTVEDVRDQWDEINDFTESRHPTSNKD 476
G++LK E+ +T + +WD++ DF+ ++PT D
Sbjct: 254 SGLLLKADES--YTPGAIIKKWDQVTDFSNPQYPTGPND 290
>sp|Q02207|FOX2_YEAST Peroxisomal hydratase-dehydrogenase-epimerase (HDE)
(Multifunctional beta-oxidation protein) (MFP)
[Includes: 2-enoyl-CoA hydratase ; D-3-hydroxyacyl CoA
dehydrogenase ]
Length = 900
Score = 169 bits (429), Expect = 7e-42
Identities = 86/163 (52%), Positives = 113/163 (69%), Gaps = 5/163 (3%)
Frame = +3
Query: 3 AWNYMRNQKFGRIIFTSSSSGIYGNFGQANYSAAKLGLVGLCNTLAIEGAKYNIKCNTIA 182
AW YMR+QKFGRII T+S +G++GNFGQANYSAAK+GLVGL TLA EGAKYNI N+IA
Sbjct: 135 AWPYMRSQKFGRIINTASPAGLFGNFGQANYSAAKMGLVGLAETLAKEGAKYNINVNSIA 194
Query: 183 PVAGSRLTEDVFPPELYNAFKPEYVSPLVLYLCHPSNINSGNLFEVGAGWIGKVRWEVSR 362
P+A SR+TE+V PP + PE + PLVLYL H S S ++FE+ AG+ G++RWE S
Sbjct: 195 PLARSRMTENVLPPHILKQLGPEKIVPLVLYLTHESTKVSNSIFELAAGFFGQLRWERSS 254
Query: 363 GVVLKKKENKFFTVEDVRDQWDEIND-----FTESRHPTSNKD 476
G + + K +T E + ++W EI D F +++HP D
Sbjct: 255 GQIF-NPDPKTYTPEAILNKWKEITDYRDKPFNKTQHPYQLSD 296
Score = 146 bits (368), Expect = 9e-35
Identities = 100/287 (34%), Positives = 144/287 (50%), Gaps = 8/287 (2%)
Frame = +3
Query: 6 WNYMRNQKFGRIIFTSSSSGIYGNFGQANYSAAKLGLVGLCNTLAIEGAKYNIKCNTIAP 185
W QK G II T+S+SGIYGNFGQANY+AAK ++G T+A+EGAK I N IAP
Sbjct: 440 WPIFTKQKSGFIINTTSTSGIYGNFGQANYAAAKAAILGFSKTIALEGAKRGIIVNVIAP 499
Query: 186 VAGSRLTEDVF-PPELYNAFKPEYVSPLVLYLC------HPSNINSGNLFEVGAGWIGKV 344
A + +T+ +F EL N F VSPLV+ L + G LFEVG GW G+
Sbjct: 500 HAETAMTKTIFSEKELSNHFDASQVSPLVVLLASEELQKYSGRRVIGQLFEVGGGWCGQT 559
Query: 345 RWEVSRGVVLKKKENKFFTVEDVRDQWDEINDFTESR-HPTSNKDSIQNFLEVXXXXXXX 521
RW+ S G V K+ E++++ W+ I DF+ + +P+S ++S L+
Sbjct: 560 RWQRSSGYVSIKET---IEPEEIKENWNHITDFSRNTINPSSTEESSMATLQAVQKAHS- 615
Query: 522 XXXXXXXXXXXXXXXXXXFIGKSKTSTYESISFQKAILYAISVGINNSKIENLKFLYENH 701
K + + ILY + +G + + LK+ YEN
Sbjct: 616 --------------------SKELDDGLFKYTTKDCILYNLGLGCTS---KELKYTYEND 652
Query: 702 SNFSVLPTFAVIASFDNVFNMLNEVMSASDNAFDLSQVLHGEQYLEV 842
+F VLPTFAVI + + + DN F+ + +LHGEQY ++
Sbjct: 653 PDFQVLPTFAVIPFMQATATLAMD--NLVDN-FNYAMLLHGEQYFKL 696
>sp|P22414|FOX2_CANTR Peroxisomal hydratase-dehydrogenase-epimerase (HDE)
(Multifunctional beta-oxidation protein) (MFP)
[Includes: 2-enoyl-CoA hydratase ; D-3-hydroxyacyl CoA
dehydrogenase ]
Length = 906
Score = 160 bits (404), Expect = 6e-39
Identities = 80/153 (52%), Positives = 104/153 (67%)
Frame = +3
Query: 3 AWNYMRNQKFGRIIFTSSSSGIYGNFGQANYSAAKLGLVGLCNTLAIEGAKYNIKCNTIA 182
AW Y + QK+GRI+ TSS +G+YGNFGQANY++AK L+G TLA EGAKYNIK N IA
Sbjct: 133 AWPYFQKQKYGRIVNTSSPAGLYGNFGQANYASAKSALLGFAETLAKEGAKYNIKANAIA 192
Query: 183 PVAGSRLTEDVFPPELYNAFKPEYVSPLVLYLCHPSNINSGNLFEVGAGWIGKVRWEVSR 362
P+A SR+TE + PP + PE V+PLVLYL N +G FEV AG+ ++RWE S
Sbjct: 193 PLARSRMTESILPPPMLEKLGPEKVAPLVLYLSSAENELTGQFFEVAAGFYAQIRWERSG 252
Query: 363 GVVLKKKENKFFTVEDVRDQWDEINDFTESRHP 461
GV+ K ++ FT E V ++ EI D+ +SR P
Sbjct: 253 GVLFKPDQS--FTAEVVAKRFSEILDYDDSRKP 283
Score = 160 bits (404), Expect = 6e-39
Identities = 100/282 (35%), Positives = 151/282 (53%), Gaps = 1/282 (0%)
Frame = +3
Query: 3 AWNYMRNQKFGRIIFTSSSSGIYGNFGQANYSAAKLGLVGLCNTLAIEGAKYNIKCNTIA 182
AW Y ++FGRII +S+SGIYGNFGQANYS++K G++GL T+AIEGAK NIK N +A
Sbjct: 437 AWPYFVEKQFGRIINITSTSGIYGNFGQANYSSSKAGILGLSKTMAIEGAKNNIKVNIVA 496
Query: 183 PVAGSRLTEDVFPPELYNAFKPEYVSPLVLYLCHPSNINSGNLFEVGAGWIGKVRWEVSR 362
P A + +T +F + N + + V+PL++YL +G FE+G GWIG RW+ ++
Sbjct: 497 PHAETAMTLTIFREQDKNLYHADQVAPLLVYLGTDDVPVTGETFEIGGGWIGNTRWQRAK 556
Query: 363 GVVLKKKENKFFTVEDVRDQWDEINDF-TESRHPTSNKDSIQNFLEVXXXXXXXXXXXXX 539
G V ++ TVE +++ +EI DF T++ +P S +S L
Sbjct: 557 GAV---SHDEHTTVEFIKEHLNEITDFTTDTENPKSTTESSMAILSAVGGDDDDDDEDEE 613
Query: 540 XXXXXXXXXXXXFIGKSKTSTYESISFQKAILYAISVGINNSKIENLKFLYENHSNFSVL 719
+ + + ILY I++G + + LK++YEN S+F V+
Sbjct: 614 EDEGDEEEDEE---DEEEDDPVWRFDDRDVILYNIALG---ATTKQLKYVYENDSDFQVI 667
Query: 720 PTFAVIASFDNVFNMLNEVMSASDNAFDLSQVLHGEQYLEVY 845
PTF + +F N N N F+ +LHGE YL+V+
Sbjct: 668 PTFGHLITF-NSGKSQNSFAKLLRN-FNPMLLLHGEHYLKVH 707
>sp|P50203|PHAB_ACISR Acetoacetyl-CoA reductase
Length = 248
Score = 65.5 bits (158), Expect = 2e-10
Identities = 32/60 (53%), Positives = 41/60 (68%)
Frame = +3
Query: 6 WNYMRNQKFGRIIFTSSSSGIYGNFGQANYSAAKLGLVGLCNTLAIEGAKYNIKCNTIAP 185
+N M QK GRI+ SS +G+ G FGQANYSA+K G++G LA EGA+ NI N +AP
Sbjct: 126 FNKMLEQKSGRIVNISSVNGLKGQFGQANYSASKAGIIGFTKALAQEGARSNICVNVVAP 185
>sp|Q93X68|FABG5_BRANA 3-oxoacyl-[acyl-carrier-protein] reductase 5, chloroplast precursor
(3-ketoacyl-acyl carrier protein reductase 5)
Length = 317
Score = 63.9 bits (154), Expect = 6e-10
Identities = 47/124 (37%), Positives = 66/124 (53%), Gaps = 14/124 (11%)
Frame = +3
Query: 3 AWNYMRNQKFGRIIFTSSSSGIYGNFGQANYSAAKLGLVGLCNTLAIEGAKYNIKCNTIA 182
A M ++ GRII +S G+ GN GQANY+AAK G++G T A EGA NI N +
Sbjct: 194 ATKIMMKKRKGRIINIASVVGLIGNIGQANYAAAKAGVIGFSKTAAREGASRNINVNVVC 253
Query: 183 P--VAG---SRLTEDV-------FPPELYNAFKPEYVSPLV--LYLCHPSNINSGNLFEV 320
P +A ++L ED+ P Y +PEYV+ LV L L S+ +G+ F +
Sbjct: 254 PGFIASDMTAKLGEDMEKKILGTIPLGRYG--QPEYVAGLVEFLALSPASSYITGHTFSI 311
Query: 321 GAGW 332
G+
Sbjct: 312 HGGF 315
>sp|P45375|PHBB_CHRVI Acetoacetyl-CoA reductase
Length = 246
Score = 60.8 bits (146), Expect = 5e-09
Identities = 32/60 (53%), Positives = 38/60 (63%)
Frame = +3
Query: 6 WNYMRNQKFGRIIFTSSSSGIYGNFGQANYSAAKLGLVGLCNTLAIEGAKYNIKCNTIAP 185
W+ M + FGRII SS +G G FGQANYSAAK G+ G LA EGA + NTI+P
Sbjct: 124 WDGMLERGFGRIINISSVNGQRGQFGQANYSAAKAGMHGFTMALAQEGASKGVTVNTISP 183
>sp|P73826|FABG2_SYNY3 3-oxoacyl-[acyl-carrier-protein] reductase 2 (3-ketoacyl-acyl
carrier protein reductase 2)
Length = 240
Score = 60.8 bits (146), Expect = 5e-09
Identities = 28/57 (49%), Positives = 38/57 (66%)
Frame = +3
Query: 15 MRNQKFGRIIFTSSSSGIYGNFGQANYSAAKLGLVGLCNTLAIEGAKYNIKCNTIAP 185
M +K G I+ SS SG GN GQ NYSA K G++G+ +LA EGA+Y ++ N +AP
Sbjct: 121 MYERKAGSIVAISSISGERGNVGQTNYSATKAGVIGMMKSLAREGARYGVRANAVAP 177
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 93,698,313
Number of Sequences: 369166
Number of extensions: 1775689
Number of successful extensions: 4725
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4564
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4706
length of database: 68,354,980
effective HSP length: 110
effective length of database: 48,034,130
effective search space used: 8886314050
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)