Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_016_P11
(377 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P25782|CYSP2_HOMAM Digestive cysteine proteinase 2 precu... 125 3e-29
sp|P13277|CYSP1_HOMAM Digestive cysteine proteinase 1 precu... 121 6e-28
sp|P15242|TEST2_RAT Testin 2 precursor (CMB-23) [Contains: ... 120 1e-27
sp|P25784|CYSP3_HOMAM Digestive cysteine proteinase 3 precu... 118 5e-27
sp|Q9R014|CATJ_MOUSE Cathepsin J precursor (Cathepsin P) (C... 117 6e-27
sp|Q26636|CATL_SARPE Cathepsin L precursor [Contains: Cathe... 116 2e-26
sp|O35186|CATK_RAT Cathepsin K precursor 116 2e-26
sp|Q9GLE3|CATK_PIG Cathepsin K precursor 116 2e-26
sp|Q95029|CATL_DROME Cathepsin L precursor (Cysteine protei... 115 3e-26
sp|P55097|CATK_MOUSE Cathepsin K precursor 114 9e-26
>sp|P25782|CYSP2_HOMAM Digestive cysteine proteinase 2 precursor
Length = 323
Score = 125 bits (314), Expect = 3e-29
Identities = 56/89 (62%), Positives = 71/89 (79%)
Frame = +3
Query: 3 IGPISVGIDASQRSFQHYSGNDIYYEPNCDPGHLNHAVLVVGYGSKDGKNFWIVKNSWGT 182
IGPISV IDA+ SFQ YS +YYEP+C P +L+HAVL VGYGS+ G++FW+VKNSW T
Sbjct: 236 IGPISVTIDAAHSSFQFYSSG-VYYEPSCSPSYLDHAVLAVGYGSEGGQDFWLVKNSWAT 294
Query: 183 TWGRKGYIFMSKDEDNQCGIATEANYPLM 269
+WG GYI MS++ +N CGIAT A+YPL+
Sbjct: 295 SWGDAGYIKMSRNRNNNCGIATVASYPLV 323
>sp|P13277|CYSP1_HOMAM Digestive cysteine proteinase 1 precursor
Length = 322
Score = 121 bits (303), Expect = 6e-28
Identities = 54/87 (62%), Positives = 67/87 (77%)
Frame = +3
Query: 3 IGPISVGIDASQRSFQHYSGNDIYYEPNCDPGHLNHAVLVVGYGSKDGKNFWIVKNSWGT 182
IGPISV IDAS RSFQ Y +YYEP+C L+HAVL VGYGS+ G++FW+VKNSW T
Sbjct: 235 IGPISVAIDASHRSFQSYY-TGVYYEPSCSSSQLDHAVLAVGYGSEGGQDFWLVKNSWAT 293
Query: 183 TWGRKGYIFMSKDEDNQCGIATEANYP 263
+WG GYI M+++ +N CGIAT+A YP
Sbjct: 294 SWGESGYIKMARNRNNNCGIATDACYP 320
>sp|P15242|TEST2_RAT Testin 2 precursor (CMB-23) [Contains: Testin 1 (CMB-22)]
Length = 333
Score = 120 bits (300), Expect = 1e-27
Identities = 56/93 (60%), Positives = 67/93 (72%), Gaps = 4/93 (4%)
Frame = +3
Query: 3 IGPISVGIDASQRSFQHYSGNDIYYEPNCDPGHLNHAVLVVGYG----SKDGKNFWIVKN 170
+GPISV +DAS SFQ Y G+ IYYEP C HLNHAVLVVGYG DG +FW+VKN
Sbjct: 242 VGPISVAVDASHGSFQFY-GSGIYYEPQCKRVHLNHAVLVVGYGFEGEESDGNSFWLVKN 300
Query: 171 SWGTTWGRKGYIFMSKDEDNQCGIATEANYPLM 269
SWG WG KGY+ ++KD N CGIAT + YP++
Sbjct: 301 SWGEEWGMKGYMKLAKDWSNHCGIATYSTYPIV 333
>sp|P25784|CYSP3_HOMAM Digestive cysteine proteinase 3 precursor
Length = 321
Score = 118 bits (295), Expect = 5e-27
Identities = 52/87 (59%), Positives = 66/87 (75%)
Frame = +3
Query: 3 IGPISVGIDASQRSFQHYSGNDIYYEPNCDPGHLNHAVLVVGYGSKDGKNFWIVKNSWGT 182
+GPISV IDAS SFQ YS +YYE NC P L+H VL VGYG++ K++W+VKNSWG+
Sbjct: 234 VGPISVAIDASHFSFQFYSSG-VYYEQNCSPTFLDHGVLAVGYGTESTKDYWLVKNSWGS 292
Query: 183 TWGRKGYIFMSKDEDNQCGIATEANYP 263
+WG GYI MS++ DN CGIA+E +YP
Sbjct: 293 SWGDAGYIKMSRNRDNNCGIASEPSYP 319
>sp|Q9R014|CATJ_MOUSE Cathepsin J precursor (Cathepsin P) (Catlrp-p)
Length = 333
Score = 117 bits (294), Expect = 6e-27
Identities = 54/91 (59%), Positives = 67/91 (73%), Gaps = 4/91 (4%)
Frame = +3
Query: 3 IGPISVGIDASQRSFQHYSGNDIYYEPNCDPGHLNHAVLVVGYGS----KDGKNFWIVKN 170
IGP+S IDAS SF+ Y+G IYYEPNC +NHAVLVVGYGS KDG N+W++KN
Sbjct: 241 IGPVSAAIDASHDSFRFYNGG-IYYEPNCSSYFVNHAVLVVGYGSEGDVKDGNNYWLIKN 299
Query: 171 SWGTTWGRKGYIFMSKDEDNQCGIATEANYP 263
SWG WG GY+ ++KD +N CGIA+ A+YP
Sbjct: 300 SWGEEWGMNGYMQIAKDHNNHCGIASLASYP 330
>sp|Q26636|CATL_SARPE Cathepsin L precursor [Contains: Cathepsin L heavy chain; Cathepsin
L light chain]
Length = 339
Score = 116 bits (290), Expect = 2e-26
Identities = 52/88 (59%), Positives = 70/88 (79%), Gaps = 1/88 (1%)
Frame = +3
Query: 3 IGPISVGIDASQRSFQHYSGNDIYYEPNCDPGHLNHAVLVVGYGSKD-GKNFWIVKNSWG 179
+GP+SV IDAS SFQ YS +Y EP CD +L+H VLVVGYG+ + G ++W+VKNSWG
Sbjct: 251 MGPVSVAIDASHESFQLYS-EGVYNEPECDEQNLDHGVLVVGYGTDESGMDYWLVKNSWG 309
Query: 180 TTWGRKGYIFMSKDEDNQCGIATEANYP 263
TTWG +GYI M+++++NQCGIAT ++YP
Sbjct: 310 TTWGEQGYIKMARNQNNQCGIATASSYP 337
>sp|O35186|CATK_RAT Cathepsin K precursor
Length = 329
Score = 116 bits (290), Expect = 2e-26
Identities = 48/89 (53%), Positives = 68/89 (76%)
Frame = +3
Query: 3 IGPISVGIDASQRSFQHYSGNDIYYEPNCDPGHLNHAVLVVGYGSKDGKNFWIVKNSWGT 182
+GP+SV IDAS SFQ YS +YY+ NCD ++NHAVLVVGYG++ G +WI+KNSWG
Sbjct: 242 VGPVSVSIDASLTSFQFYS-RGVYYDENCDRDNVNHAVLVVGYGTQKGNKYWIIKNSWGE 300
Query: 183 TWGRKGYIFMSKDEDNQCGIATEANYPLM 269
+WG KGY+ ++++++N CGI A++P M
Sbjct: 301 SWGNKGYVLLARNKNNACGITNLASFPKM 329
>sp|Q9GLE3|CATK_PIG Cathepsin K precursor
Length = 330
Score = 116 bits (290), Expect = 2e-26
Identities = 51/89 (57%), Positives = 66/89 (74%)
Frame = +3
Query: 3 IGPISVGIDASQRSFQHYSGNDIYYEPNCDPGHLNHAVLVVGYGSKDGKNFWIVKNSWGT 182
+GP+SV IDAS SFQ YS +YY+ NC+ +LNHAVL VGYG + GK WI+KNSWG
Sbjct: 243 VGPVSVAIDASLTSFQFYS-KGVYYDENCNSDNLNHAVLAVGYGIQKGKKHWIIKNSWGE 301
Query: 183 TWGRKGYIFMSKDEDNQCGIATEANYPLM 269
WG KGYI M+++++N CGIA A++P M
Sbjct: 302 NWGNKGYILMARNKNNACGIANLASFPKM 330
>sp|Q95029|CATL_DROME Cathepsin L precursor (Cysteine proteinase 1) [Contains: Cathepsin
L heavy chain; Cathepsin L light chain]
Length = 341
Score = 115 bits (288), Expect = 3e-26
Identities = 51/90 (56%), Positives = 72/90 (80%), Gaps = 1/90 (1%)
Frame = +3
Query: 3 IGPISVGIDASQRSFQHYSGNDIYYEPNCDPGHLNHAVLVVGYGSKD-GKNFWIVKNSWG 179
+GP+SV IDAS SFQ YS +Y EP CD +L+H VLVVG+G+ + G+++W+VKNSWG
Sbjct: 253 VGPVSVAIDASHESFQFYS-EGVYNEPQCDAQNLDHGVLVVGFGTDESGEDYWLVKNSWG 311
Query: 180 TTWGRKGYIFMSKDEDNQCGIATEANYPLM 269
TTWG KG+I M ++++NQCGIA+ ++YPL+
Sbjct: 312 TTWGDKGFIKMLRNKENQCGIASASSYPLV 341
>sp|P55097|CATK_MOUSE Cathepsin K precursor
Length = 329
Score = 114 bits (284), Expect = 9e-26
Identities = 49/89 (55%), Positives = 66/89 (74%)
Frame = +3
Query: 3 IGPISVGIDASQRSFQHYSGNDIYYEPNCDPGHLNHAVLVVGYGSKDGKNFWIVKNSWGT 182
+GPISV IDAS SFQ YS +YY+ NCD ++NHAVLVVGYG++ G WI+KNSWG
Sbjct: 242 VGPISVSIDASLASFQFYS-RGVYYDENCDRDNVNHAVLVVGYGTQKGSKHWIIKNSWGE 300
Query: 183 TWGRKGYIFMSKDEDNQCGIATEANYPLM 269
+WG KGY ++++++N CGI A++P M
Sbjct: 301 SWGNKGYALLARNKNNACGITNMASFPKM 329
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 39,747,653
Number of Sequences: 369166
Number of extensions: 738039
Number of successful extensions: 2521
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 2266
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 2367
length of database: 68,354,980
effective HSP length: 92
effective length of database: 51,359,360
effective search space used: 1694858880
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)