Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_016_P07
(754 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9CZU6|CISY_MOUSE Citrate synthase, mitochondrial precursor 367 e-101
sp|P00889|CISY_PIG Citrate synthase, mitochondrial precursor 365 e-101
sp|O75390|CISY_HUMAN Citrate synthase, mitochondrial precursor 365 e-101
sp|P34575|CISY_CAEEL Probable citrate synthase, mitochondri... 362 e-100
sp|P23007|CISY_CHICK Citrate synthase, mitochondrial 356 4e-98
sp|O80433|CISY_DAUCA Citrate synthase, mitochondrial precursor 306 4e-83
sp|P51044|CISY_ASPNG Citrate synthase, mitochondrial precursor 306 4e-83
sp|P20115|CISY4_ARATH Citrate synthase 4, mitochondrial pre... 305 9e-83
sp|O00098|CISY_EMENI Citrate synthase, mitochondrial precursor 301 2e-81
sp|P00890|CISY1_YEAST Citrate synthase, mitochondrial precu... 300 2e-81
>sp|Q9CZU6|CISY_MOUSE Citrate synthase, mitochondrial precursor
Length = 464
Score = 367 bits (943), Expect = e-101
Identities = 173/248 (69%), Positives = 209/248 (84%)
Frame = +3
Query: 3 WASRADLPGHVVSMINNFPSSLHPMSQLVAASAALNSESKFVKAYHEGVSKSVYWETVYE 182
WA RA LP HVV+M++NFP++LHPMSQL AA ALNSES F +AY EG++++ YWE +YE
Sbjct: 141 WAKRAALPSHVVTMLDNFPTNLHPMSQLSAAITALNSESNFARAYAEGMNRAKYWELIYE 200
Query: 183 DSMDLIAKLSTVAAMIYRNLYRDGTSVGCIDNSKDWSENFVRMIGYEDPSFTELMRLYLT 362
D MDLIAKL VAA IYRNLYR+G+S+G ID+ DWS NF M+GY DP FTELMRLYLT
Sbjct: 201 DCMDLIAKLPCVAAKIYRNLYREGSSIGAIDSRLDWSHNFTNMLGYTDPQFTELMRLYLT 260
Query: 363 IHSDHEGGNVSAHTCHLVGSALSDPYLSYAAAMCGLAGPLHGLANQEVLLWVQKMIEVIG 542
IHSDHEGGNVSAHT HLVGSALSDPYLS+AAAM GLAGPLHGLANQEVL+W+ ++ + +G
Sbjct: 261 IHSDHEGGNVSAHTSHLVGSALSDPYLSFAAAMNGLAGPLHGLANQEVLVWLTQLQKEVG 320
Query: 543 TKPTDKDIVEFIEKTLKAGQVVPGYGHAVLRKTDPRYMCQREFALKHLPDYPLFKVVSQL 722
+D+ + ++I TL +G+VVPGYGHAVLRKTDPRY CQREFALKHLP P+FK+V+QL
Sbjct: 321 KDVSDEKLRDYIWNTLNSGRVVPGYGHAVLRKTDPRYSCQREFALKHLPKDPMFKLVAQL 380
Query: 723 YQIVPDVL 746
Y+IVP++L
Sbjct: 381 YKIVPNIL 388
>sp|P00889|CISY_PIG Citrate synthase, mitochondrial precursor
Length = 464
Score = 365 bits (937), Expect = e-101
Identities = 173/248 (69%), Positives = 207/248 (83%)
Frame = +3
Query: 3 WASRADLPGHVVSMINNFPSSLHPMSQLVAASAALNSESKFVKAYHEGVSKSVYWETVYE 182
WA RA LP HVV+M++NFP++LHPMSQL AA ALNSES F +AY EG+ ++ YWE +YE
Sbjct: 141 WAKRAALPSHVVTMLDNFPTNLHPMSQLSAAITALNSESNFARAYAEGIHRTKYWELIYE 200
Query: 183 DSMDLIAKLSTVAAMIYRNLYRDGTSVGCIDNSKDWSENFVRMIGYEDPSFTELMRLYLT 362
D MDLIAKL VAA IYRNLYR+G+S+G ID+ DWS NF M+GY D FTELMRLYLT
Sbjct: 201 DCMDLIAKLPCVAAKIYRNLYREGSSIGAIDSKLDWSHNFTNMLGYTDAQFTELMRLYLT 260
Query: 363 IHSDHEGGNVSAHTCHLVGSALSDPYLSYAAAMCGLAGPLHGLANQEVLLWVQKMIEVIG 542
IHSDHEGGNVSAHT HLVGSALSDPYLS+AAAM GLAGPLHGLANQEVL+W+ ++ + +G
Sbjct: 261 IHSDHEGGNVSAHTSHLVGSALSDPYLSFAAAMNGLAGPLHGLANQEVLVWLTQLQKEVG 320
Query: 543 TKPTDKDIVEFIEKTLKAGQVVPGYGHAVLRKTDPRYMCQREFALKHLPDYPLFKVVSQL 722
+D+ + ++I TL +G+VVPGYGHAVLRKTDPRY CQREFALKHLP P+FK+V+QL
Sbjct: 321 KDVSDEKLRDYIWNTLNSGRVVPGYGHAVLRKTDPRYTCQREFALKHLPHDPMFKLVAQL 380
Query: 723 YQIVPDVL 746
Y+IVP+VL
Sbjct: 381 YKIVPNVL 388
>sp|O75390|CISY_HUMAN Citrate synthase, mitochondrial precursor
Length = 466
Score = 365 bits (936), Expect = e-101
Identities = 172/248 (69%), Positives = 209/248 (84%)
Frame = +3
Query: 3 WASRADLPGHVVSMINNFPSSLHPMSQLVAASAALNSESKFVKAYHEGVSKSVYWETVYE 182
WA RA LP HVV+M++NFP++LHPMSQL AA ALNSES F +AY +G+S++ YWE +YE
Sbjct: 141 WAKRAALPSHVVTMLDNFPTNLHPMSQLSAAVTALNSESNFARAYAQGISRTKYWELIYE 200
Query: 183 DSMDLIAKLSTVAAMIYRNLYRDGTSVGCIDNSKDWSENFVRMIGYEDPSFTELMRLYLT 362
DSMDLIAKL VAA IYRNLYR+G+ +G ID++ DWS NF M+GY D FTEL RLYLT
Sbjct: 201 DSMDLIAKLPCVAAKIYRNLYREGSGIGAIDSNLDWSHNFTNMLGYTDHQFTELTRLYLT 260
Query: 363 IHSDHEGGNVSAHTCHLVGSALSDPYLSYAAAMCGLAGPLHGLANQEVLLWVQKMIEVIG 542
IHSDHEGGNVSAHT HLVGSALSDPYLS+AAAM GLAGPLHGLANQEVL+W+ ++ + +G
Sbjct: 261 IHSDHEGGNVSAHTSHLVGSALSDPYLSFAAAMNGLAGPLHGLANQEVLVWLTQLQKEVG 320
Query: 543 TKPTDKDIVEFIEKTLKAGQVVPGYGHAVLRKTDPRYMCQREFALKHLPDYPLFKVVSQL 722
+D+ + ++I TL +G+VVPGYGHAVLRKTDPRY CQREFALKHLP+ P+FK+V+QL
Sbjct: 321 KDVSDEKLRDYIWNTLNSGRVVPGYGHAVLRKTDPRYTCQREFALKHLPNDPMFKLVAQL 380
Query: 723 YQIVPDVL 746
Y+IVP+VL
Sbjct: 381 YKIVPNVL 388
>sp|P34575|CISY_CAEEL Probable citrate synthase, mitochondrial precursor
Length = 468
Score = 362 bits (928), Expect = e-100
Identities = 174/248 (70%), Positives = 206/248 (83%)
Frame = +3
Query: 3 WASRADLPGHVVSMINNFPSSLHPMSQLVAASAALNSESKFVKAYHEGVSKSVYWETVYE 182
W +RADLP HVV M++NFP +LHPM+Q +AA AALN+ESKF AY GV+K+ YWE YE
Sbjct: 143 WNARADLPTHVVRMLDNFPDNLHPMAQFIAAIAALNNESKFAGAYARGVAKASYWEYAYE 202
Query: 183 DSMDLIAKLSTVAAMIYRNLYRDGTSVGCIDNSKDWSENFVRMIGYEDPSFTELMRLYLT 362
DSMDL+AKL TVAA+IYRNLYRDG++V ID KDWS NF M+GY+DP F ELMRLYL
Sbjct: 203 DSMDLLAKLPTVAAIIYRNLYRDGSAVSVIDPKKDWSANFSSMLGYDDPLFAELMRLYLV 262
Query: 363 IHSDHEGGNVSAHTCHLVGSALSDPYLSYAAAMCGLAGPLHGLANQEVLLWVQKMIEVIG 542
IHSDHEGGNVSAHT HLVGSALSDPYLS++AAM GLAGPLHGLANQEVL+++ K++ IG
Sbjct: 263 IHSDHEGGNVSAHTSHLVGSALSDPYLSFSAAMAGLAGPLHGLANQEVLVFLNKIVGEIG 322
Query: 543 TKPTDKDIVEFIEKTLKAGQVVPGYGHAVLRKTDPRYMCQREFALKHLPDYPLFKVVSQL 722
T++ + E++ K LK+GQVVPGYGHAVLRKTDPRY CQREFALKHLP+ LFK+VS L
Sbjct: 323 FNYTEEQLKEWVWKHLKSGQVVPGYGHAVLRKTDPRYECQREFALKHLPNDDLFKLVSTL 382
Query: 723 YQIVPDVL 746
Y+I P +L
Sbjct: 383 YKITPGIL 390
>sp|P23007|CISY_CHICK Citrate synthase, mitochondrial
Length = 433
Score = 356 bits (913), Expect = 4e-98
Identities = 172/248 (69%), Positives = 201/248 (81%)
Frame = +3
Query: 3 WASRADLPGHVVSMINNFPSSLHPMSQLVAASAALNSESKFVKAYHEGVSKSVYWETVYE 182
WA RA LP HVV+M++NFP++LHPMSQL AA ALNSES F +AY EG+ ++ YWE VYE
Sbjct: 114 WAKRAALPSHVVTMLDNFPTNLHPMSQLSAAITALNSESNFARAYAEGILRTKYWEMVYE 173
Query: 183 DSMDLIAKLSTVAAMIYRNLYRDGTSVGCIDNSKDWSENFVRMIGYEDPSFTELMRLYLT 362
+MDLIAKL VAA IYRNLYR G+S+G ID+ DWS NF M+GY D FTELMRLYLT
Sbjct: 174 SAMDLIAKLPCVAAKIYRNLYRAGSSIGAIDSKLDWSHNFTNMLGYTDAQFTELMRLYLT 233
Query: 363 IHSDHEGGNVSAHTCHLVGSALSDPYLSYAAAMCGLAGPLHGLANQEVLLWVQKMIEVIG 542
IHSDHEGGNVSAHT HLVGSALSDPYLS+AAAM GLAGPLHGLANQEVL W+ ++ +
Sbjct: 234 IHSDHEGGNVSAHTSHLVGSALSDPYLSFAAAMNGLAGPLHGLANQEVLGWLAQLQKAXX 293
Query: 543 TKPTDKDIVEFIEKTLKAGQVVPGYGHAVLRKTDPRYMCQREFALKHLPDYPLFKVVSQL 722
D + ++I TL +G+VVPGYGHAVLRKTDPRY CQREFALKHLP P+FK+V+QL
Sbjct: 294 XAGADASLRDYIWNTLNSGRVVPGYGHAVLRKTDPRYTCQREFALKHLPGDPMFKLVAQL 353
Query: 723 YQIVPDVL 746
Y+IVP+VL
Sbjct: 354 YKIVPNVL 361
>sp|O80433|CISY_DAUCA Citrate synthase, mitochondrial precursor
Length = 472
Score = 306 bits (784), Expect = 4e-83
Identities = 146/246 (59%), Positives = 186/246 (75%)
Frame = +3
Query: 9 SRADLPGHVVSMINNFPSSLHPMSQLVAASAALNSESKFVKAYHEGVSKSVYWETVYEDS 188
SRA +P HV I+ P + HPM+Q AL +S+F KAY +G+ K+ YWE YEDS
Sbjct: 151 SRAAVPEHVYKTIDALPVTAHPMTQFATGVMALQVQSEFQKAYEKGIHKTKYWEPTYEDS 210
Query: 189 MDLIAKLSTVAAMIYRNLYRDGTSVGCIDNSKDWSENFVRMIGYEDPSFTELMRLYLTIH 368
+ LIA+L VAA IYR +Y++G S+ D+S D+ NF M+GY+ PS ELMRLY+TIH
Sbjct: 211 ITLIAQLPVVAAYIYRRMYKNGQSIST-DDSLDYGANFAHMLGYDSPSMQELMRLYVTIH 269
Query: 369 SDHEGGNVSAHTCHLVGSALSDPYLSYAAAMCGLAGPLHGLANQEVLLWVQKMIEVIGTK 548
+DHEGGNVSAHT HLV SALSDPYLS+AAA+ GLAGPLHGLANQEVLLW++ ++ G
Sbjct: 270 TDHEGGNVSAHTGHLVASALSDPYLSFAAALNGLAGPLHGLANQEVLLWIKSVVSECGEN 329
Query: 549 PTDKDIVEFIEKTLKAGQVVPGYGHAVLRKTDPRYMCQREFALKHLPDYPLFKVVSQLYQ 728
T + + ++I KTL +G+VVPGYGH VLR TDPRY+CQREFALKHLPD PLF++VS L++
Sbjct: 330 VTKEQLKDYIWKTLNSGKVVPGYGHGVLRNTDPRYICQREFALKHLPDDPLFQLVSNLFE 389
Query: 729 IVPDVL 746
+VP +L
Sbjct: 390 VVPPIL 395
>sp|P51044|CISY_ASPNG Citrate synthase, mitochondrial precursor
Length = 475
Score = 306 bits (784), Expect = 4e-83
Identities = 156/249 (62%), Positives = 185/249 (74%), Gaps = 1/249 (0%)
Frame = +3
Query: 3 WASRADLPGHVVSMINNFPSSLHPMSQLVAASAALNSESKFVKAYHEGVSKSVYWETVYE 182
WA+R+DLP + +I+ PS+LHPMSQ A AL ES F KAY +G++K YW +E
Sbjct: 150 WAARSDLPKFIEELIDRCPSTLHPMSQFSLAVTALEHESAFAKAYAKGINKKDYWNYTFE 209
Query: 183 DSMDLIAKLSTVAAMIYRNLYRDGTSVGCIDNSKDWSENFVRMIGYEDPS-FTELMRLYL 359
DSMDLIAKL T+AA IYRN+++DG V I KD+S N +GY D + F ELMRLYL
Sbjct: 210 DSMDLIAKLPTIAAKIYRNVFKDG-KVAPIQKDKDYSYNLANQLGYGDNNDFVELMRLYL 268
Query: 360 TIHSDHEGGNVSAHTCHLVGSALSDPYLSYAAAMCGLAGPLHGLANQEVLLWVQKMIEVI 539
TIHSDHEGGNVSAHT HLVGSALS P LS AA + GLAGPLHGLANQEVL W+ KM I
Sbjct: 269 TIHSDHEGGNVSAHTTHLVGSALSSPMLSLAAGLNGLAGPLHGLANQEVLNWLTKMKAAI 328
Query: 540 GTKPTDKDIVEFIEKTLKAGQVVPGYGHAVLRKTDPRYMCQREFALKHLPDYPLFKVVSQ 719
G +D+ I ++ TL AGQVVPGYGHAVLRKTDPRY+ QREFAL+ LPD P+FK+VSQ
Sbjct: 329 GNDLSDEAIKNYLWSTLNAGQVVPGYGHAVLRKTDPRYVSQREFALRKLPDDPMFKLVSQ 388
Query: 720 LYQIVPDVL 746
+Y+I P VL
Sbjct: 389 VYKIAPGVL 397
>sp|P20115|CISY4_ARATH Citrate synthase 4, mitochondrial precursor
Length = 474
Score = 305 bits (781), Expect = 9e-83
Identities = 144/247 (58%), Positives = 190/247 (76%)
Frame = +3
Query: 6 ASRADLPGHVVSMINNFPSSLHPMSQLVAASAALNSESKFVKAYHEGVSKSVYWETVYED 185
A+RA +P +V + I+ PS+ HPM+Q + AL +S+F KAY G+ KS +WE YED
Sbjct: 150 ANRAAVPDYVYNAIDALPSTAHPMTQFASGVMALQVQSEFQKAYENGIHKSKFWEPTYED 209
Query: 186 SMDLIAKLSTVAAMIYRNLYRDGTSVGCIDNSKDWSENFVRMIGYEDPSFTELMRLYLTI 365
++LIA++ VAA +YR +Y++G S+ D S D+ NF M+G++D ELMRLY+TI
Sbjct: 210 CLNLIARVPVVAAYVYRRMYKNGDSIPS-DKSLDYGANFSHMLGFDDEKVKELMRLYITI 268
Query: 366 HSDHEGGNVSAHTCHLVGSALSDPYLSYAAAMCGLAGPLHGLANQEVLLWVQKMIEVIGT 545
HSDHEGGNVSAHT HLVGSALSDPYLS+AAA+ GLAGPLHGLANQEVLLW++ ++E G
Sbjct: 269 HSDHEGGNVSAHTGHLVGSALSDPYLSFAAALNGLAGPLHGLANQEVLLWIKSVVEECGE 328
Query: 546 KPTDKDIVEFIEKTLKAGQVVPGYGHAVLRKTDPRYMCQREFALKHLPDYPLFKVVSQLY 725
+ + + E++ KTL +G+V+PGYGH VLR TDPRY+CQREFALKHLPD PLF++VS+LY
Sbjct: 329 DISKEQLKEYVWKTLNSGKVIPGYGHGVLRNTDPRYVCQREFALKHLPDDPLFQLVSKLY 388
Query: 726 QIVPDVL 746
++VP VL
Sbjct: 389 EVVPPVL 395
>sp|O00098|CISY_EMENI Citrate synthase, mitochondrial precursor
Length = 474
Score = 301 bits (770), Expect = 2e-81
Identities = 151/249 (60%), Positives = 185/249 (74%), Gaps = 1/249 (0%)
Frame = +3
Query: 3 WASRADLPGHVVSMINNFPSSLHPMSQLVAASAALNSESKFVKAYHEGVSKSVYWETVYE 182
WA+R+DLP + +I+ PS+LHPM+Q A AL ES F KA +G++K YW +E
Sbjct: 150 WAARSDLPKFIEELIDRVPSTLHPMAQFSLAVTALEHESAFAKATAKGINKKEYWHYTFE 209
Query: 183 DSMDLIAKLSTVAAMIYRNLYRDGTSVGCIDNSKDWSENFVRMIGYED-PSFTELMRLYL 359
DSMDLIAKL T+AA IYRN+++DG V I KD+S N +G+ D F ELMRLYL
Sbjct: 210 DSMDLIAKLPTIAAKIYRNVFKDG-KVAPIQKDKDYSYNLANQLGFADNKDFVELMRLYL 268
Query: 360 TIHSDHEGGNVSAHTCHLVGSALSDPYLSYAAAMCGLAGPLHGLANQEVLLWVQKMIEVI 539
TIHSDHEGGNVSAHT HLVGSALS P LS AA + GLAGPLHGLANQEVL W+ +M +V+
Sbjct: 269 TIHSDHEGGNVSAHTTHLVGSALSSPMLSLAAGLNGLAGPLHGLANQEVLNWLTEMKKVV 328
Query: 540 GTKPTDKDIVEFIEKTLKAGQVVPGYGHAVLRKTDPRYMCQREFALKHLPDYPLFKVVSQ 719
G +D+ I +++ TL AG+VVPGYGHAVLRKTDPRY QREFAL+ LPD P+FK+VSQ
Sbjct: 329 GNDLSDQSIKDYLWSTLNAGRVVPGYGHAVLRKTDPRYTSQREFALRKLPDDPMFKLVSQ 388
Query: 720 LYQIVPDVL 746
+Y+I P VL
Sbjct: 389 VYKIAPGVL 397
>sp|P00890|CISY1_YEAST Citrate synthase, mitochondrial precursor
Length = 479
Score = 300 bits (769), Expect = 2e-81
Identities = 144/249 (57%), Positives = 186/249 (74%)
Frame = +3
Query: 6 ASRADLPGHVVSMINNFPSSLHPMSQLVAASAALNSESKFVKAYHEGVSKSVYWETVYED 185
A+R+++P HV+ ++++ P LHPM+Q A AL SESKF KAY +GVSK YW +ED
Sbjct: 154 AARSEIPEHVIQLLDSLPKDLHPMAQFSIAVTALESESKFAKAYAQGVSKKEYWSYTFED 213
Query: 186 SMDLIAKLSTVAAMIYRNLYRDGTSVGCIDNSKDWSENFVRMIGYEDPSFTELMRLYLTI 365
S+DL+ KL +A+ IYRN+++DG + D + D+ +N +++GYE+ F +LMRLYLTI
Sbjct: 214 SLDLLGKLPVIASKIYRNVFKDG-KITSTDPNADYGKNLAQLLGYENKDFIDLMRLYLTI 272
Query: 366 HSDHEGGNVSAHTCHLVGSALSDPYLSYAAAMCGLAGPLHGLANQEVLLWVQKMIEVIGT 545
HSDHEGGNVSAHT HLVGSALS PYLS AA + GLAGPLHG ANQEVL W+ K+ E +
Sbjct: 273 HSDHEGGNVSAHTTHLVGSALSSPYLSLAAGLNGLAGPLHGRANQEVLEWLFKLREEVKG 332
Query: 546 KPTDKDIVEFIEKTLKAGQVVPGYGHAVLRKTDPRYMCQREFALKHLPDYPLFKVVSQLY 725
+ + I +++ TL AG+VVPGYGHAVLRKTDPRY QREFALKH PDY LFK+VS +Y
Sbjct: 333 DYSKETIEKYLWDTLNAGRVVPGYGHAVLRKTDPRYTAQREFALKHFPDYELFKLVSTIY 392
Query: 726 QIVPDVLGK 752
++ P VL K
Sbjct: 393 EVAPGVLTK 401
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 89,714,038
Number of Sequences: 369166
Number of extensions: 1899693
Number of successful extensions: 5276
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4872
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5135
length of database: 68,354,980
effective HSP length: 108
effective length of database: 48,403,600
effective search space used: 6873311200
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)