Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= Dr_sW_016_O16 (524 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|P49448|DHE4_HUMAN Glutamate dehydrogenase 2, mitochondri... 283 1e-76 sp|Q64HZ8|DHE4_PANTR Glutamate dehydrogenase 2, mitochondri... 283 1e-76 sp|Q64I01|DHE4_GORGO Glutamate dehydrogenase 2, mitochondri... 283 1e-76 sp|Q64HZ9|DHE4_HYLLA Glutamate dehydrogenase 2, mitochondri... 281 5e-76 sp|Q64I00|DHE4_PONPY Glutamate dehydrogenase 2, mitochondri... 281 5e-76 sp|P00366|DHE3_BOVIN Glutamate dehydrogenase 1, mitochondri... 281 5e-76 sp|P26443|DHE3_MOUSE Glutamate dehydrogenase 1, mitochondri... 281 7e-76 sp|P00367|DHE3_HUMAN Glutamate dehydrogenase 1, mitochondri... 281 7e-76 sp|P10860|DHE3_RAT Glutamate dehydrogenase 1, mitochondrial... 279 3e-75 sp|P82264|DHE3_CHAAC GLutamate dehydrogenase (GDH) 278 7e-75
>sp|P49448|DHE4_HUMAN Glutamate dehydrogenase 2, mitochondrial precursor (GDH) Length = 558 Score = 283 bits (725), Expect = 1e-76 Identities = 136/174 (78%), Positives = 155/174 (89%) Frame = +3 Query: 3 GIRYSMDVSKDEVKALAALMTYKCAVVDVPFGGAKAGLRIDPRLYTVGELERITRRFTVE 182 GIRYS DVS DEVKALA+LMTYKCAVVDVPFGGAKAG++I+P+ YT ELE+ITRRFT+E Sbjct: 149 GIRYSTDVSVDEVKALASLMTYKCAVVDVPFGGAKAGVKINPKNYTENELEKITRRFTME 208 Query: 183 LAKKNFIGPGVDVPAPDMGTGEREMAWIANTFAHTRGDNDLHASACVTGKPISQGGIHGR 362 LAKK FIGPGVDVPAPDM TGEREM+WIA+T+A T G D++A ACVTGKPISQGGIHGR Sbjct: 209 LAKKGFIGPGVDVPAPDMNTGEREMSWIADTYASTIGHYDINAHACVTGKPISQGGIHGR 268 Query: 363 ISATGRGVYHGIENFIHNPDMVDKLGITPGFKDKTFIIQGFGNVGLHSMRYLVR 524 ISATGRGV+HGIENFI+ + LG+TPGF+DKTF++QGFGNVGLHSMRYL R Sbjct: 269 ISATGRGVFHGIENFINEASYMSILGMTPGFRDKTFVVQGFGNVGLHSMRYLHR 322
>sp|Q64HZ8|DHE4_PANTR Glutamate dehydrogenase 2, mitochondrial precursor (GDH) Length = 558 Score = 283 bits (725), Expect = 1e-76 Identities = 136/174 (78%), Positives = 155/174 (89%) Frame = +3 Query: 3 GIRYSMDVSKDEVKALAALMTYKCAVVDVPFGGAKAGLRIDPRLYTVGELERITRRFTVE 182 GIRYS DVS DEVKALA+LMTYKCAVVDVPFGGAKAG++I+P+ YT ELE+ITRRFT+E Sbjct: 149 GIRYSTDVSVDEVKALASLMTYKCAVVDVPFGGAKAGVKINPKNYTENELEKITRRFTME 208 Query: 183 LAKKNFIGPGVDVPAPDMGTGEREMAWIANTFAHTRGDNDLHASACVTGKPISQGGIHGR 362 LAKK FIGPGVDVPAPDM TGEREM+WIA+T+A T G D++A ACVTGKPISQGGIHGR Sbjct: 209 LAKKGFIGPGVDVPAPDMNTGEREMSWIADTYASTIGHYDINAHACVTGKPISQGGIHGR 268 Query: 363 ISATGRGVYHGIENFIHNPDMVDKLGITPGFKDKTFIIQGFGNVGLHSMRYLVR 524 ISATGRGV+HGIENFI+ + LG+TPGF+DKTF++QGFGNVGLHSMRYL R Sbjct: 269 ISATGRGVFHGIENFINEASYMSILGMTPGFRDKTFVVQGFGNVGLHSMRYLHR 322
>sp|Q64I01|DHE4_GORGO Glutamate dehydrogenase 2, mitochondrial precursor (GDH) Length = 558 Score = 283 bits (725), Expect = 1e-76 Identities = 136/174 (78%), Positives = 155/174 (89%) Frame = +3 Query: 3 GIRYSMDVSKDEVKALAALMTYKCAVVDVPFGGAKAGLRIDPRLYTVGELERITRRFTVE 182 GIRYS DVS DEVKALA+LMTYKCAVVDVPFGGAKAG++I+P+ YT ELE+ITRRFT+E Sbjct: 149 GIRYSTDVSVDEVKALASLMTYKCAVVDVPFGGAKAGVKINPKNYTENELEKITRRFTME 208 Query: 183 LAKKNFIGPGVDVPAPDMGTGEREMAWIANTFAHTRGDNDLHASACVTGKPISQGGIHGR 362 LAKK FIGPGVDVPAPDM TGEREM+WIA+T+A T G D++A ACVTGKPISQGGIHGR Sbjct: 209 LAKKGFIGPGVDVPAPDMNTGEREMSWIADTYASTIGHYDINAHACVTGKPISQGGIHGR 268 Query: 363 ISATGRGVYHGIENFIHNPDMVDKLGITPGFKDKTFIIQGFGNVGLHSMRYLVR 524 ISATGRGV+HGIENFI+ + LG+TPGF+DKTF++QGFGNVGLHSMRYL R Sbjct: 269 ISATGRGVFHGIENFINEASYMSILGMTPGFRDKTFVVQGFGNVGLHSMRYLHR 322
>sp|Q64HZ9|DHE4_HYLLA Glutamate dehydrogenase 2, mitochondrial precursor (GDH) Length = 555 Score = 281 bits (720), Expect = 5e-76 Identities = 135/174 (77%), Positives = 154/174 (88%) Frame = +3 Query: 3 GIRYSMDVSKDEVKALAALMTYKCAVVDVPFGGAKAGLRIDPRLYTVGELERITRRFTVE 182 GIRYS DVS DEVKALA+LMTYKCAVVDVPFGGAKAG++I+P+ YT ELE+ITRRFT+E Sbjct: 146 GIRYSADVSVDEVKALASLMTYKCAVVDVPFGGAKAGVKINPKNYTENELEKITRRFTME 205 Query: 183 LAKKNFIGPGVDVPAPDMGTGEREMAWIANTFAHTRGDNDLHASACVTGKPISQGGIHGR 362 LAKK FIGPG+DVPAPDM TGEREM+WIA+T+A T G D++A ACVTGKPISQGGIHGR Sbjct: 206 LAKKGFIGPGIDVPAPDMNTGEREMSWIADTYASTIGHYDINAHACVTGKPISQGGIHGR 265 Query: 363 ISATGRGVYHGIENFIHNPDMVDKLGITPGFKDKTFIIQGFGNVGLHSMRYLVR 524 ISATGRGV+HGIENFI+ + LG+TPGF DKTF++QGFGNVGLHSMRYL R Sbjct: 266 ISATGRGVFHGIENFINEASYMSILGMTPGFGDKTFVVQGFGNVGLHSMRYLHR 319
>sp|Q64I00|DHE4_PONPY Glutamate dehydrogenase 2, mitochondrial precursor (GDH) Length = 558 Score = 281 bits (720), Expect = 5e-76 Identities = 134/174 (77%), Positives = 154/174 (88%) Frame = +3 Query: 3 GIRYSMDVSKDEVKALAALMTYKCAVVDVPFGGAKAGLRIDPRLYTVGELERITRRFTVE 182 GIRYS DVS DEVKALA+LMTYKCAVVDVPFGGAKAG++I+P+ YT ELE+ITRRFT+E Sbjct: 149 GIRYSTDVSVDEVKALASLMTYKCAVVDVPFGGAKAGVKINPKNYTENELEKITRRFTME 208 Query: 183 LAKKNFIGPGVDVPAPDMGTGEREMAWIANTFAHTRGDNDLHASACVTGKPISQGGIHGR 362 LAKK FIGPG+DVPAPDM TGEREM+WIA+T+A T G D++A ACVTGKPISQGGIHGR Sbjct: 209 LAKKGFIGPGIDVPAPDMNTGEREMSWIADTYASTIGHYDINAHACVTGKPISQGGIHGR 268 Query: 363 ISATGRGVYHGIENFIHNPDMVDKLGITPGFKDKTFIIQGFGNVGLHSMRYLVR 524 ISATGRGV+HGIENFI+ + +G+TPGF DKTF++QGFGNVGLHSMRYL R Sbjct: 269 ISATGRGVFHGIENFINEASYMSNVGMTPGFGDKTFVVQGFGNVGLHSMRYLHR 322
>sp|P00366|DHE3_BOVIN Glutamate dehydrogenase 1, mitochondrial precursor (GDH) Length = 558 Score = 281 bits (720), Expect = 5e-76 Identities = 136/174 (78%), Positives = 154/174 (88%) Frame = +3 Query: 3 GIRYSMDVSKDEVKALAALMTYKCAVVDVPFGGAKAGLRIDPRLYTVGELERITRRFTVE 182 GIRYS DVS DEVKALA+LMTYKCAVVDVPFGGAKAG++I+P+ YT ELE+ITRRFT+E Sbjct: 149 GIRYSTDVSVDEVKALASLMTYKCAVVDVPFGGAKAGVKINPKNYTDNELEKITRRFTME 208 Query: 183 LAKKNFIGPGVDVPAPDMGTGEREMAWIANTFAHTRGDNDLHASACVTGKPISQGGIHGR 362 LAKK FIGPGVDVPAPDM TGEREM+WIA+T+A T G D++A ACVTGKPISQGGIHGR Sbjct: 209 LAKKGFIGPGVDVPAPDMSTGEREMSWIADTYASTIGHYDINAHACVTGKPISQGGIHGR 268 Query: 363 ISATGRGVYHGIENFIHNPDMVDKLGITPGFKDKTFIIQGFGNVGLHSMRYLVR 524 ISATGRGV+HGIENFI+ + LG+TPGF DKTF++QGFGNVGLHSMRYL R Sbjct: 269 ISATGRGVFHGIENFINEASYMSILGMTPGFGDKTFVVQGFGNVGLHSMRYLHR 322
>sp|P26443|DHE3_MOUSE Glutamate dehydrogenase 1, mitochondrial precursor (GDH) Length = 558 Score = 281 bits (719), Expect = 7e-76 Identities = 135/174 (77%), Positives = 154/174 (88%) Frame = +3 Query: 3 GIRYSMDVSKDEVKALAALMTYKCAVVDVPFGGAKAGLRIDPRLYTVGELERITRRFTVE 182 GIRYS DVS DEVKALA+LMTYKCAVVDVPFGGAKAG++I+P+ YT ELE+ITRRFT+E Sbjct: 149 GIRYSTDVSVDEVKALASLMTYKCAVVDVPFGGAKAGVKINPKNYTDNELEKITRRFTME 208 Query: 183 LAKKNFIGPGVDVPAPDMGTGEREMAWIANTFAHTRGDNDLHASACVTGKPISQGGIHGR 362 LAKK FIGPG+DVPAPDM TGEREM+WIA+T+A T G D++A ACVTGKPISQGGIHGR Sbjct: 209 LAKKGFIGPGIDVPAPDMSTGEREMSWIADTYASTIGHYDINAHACVTGKPISQGGIHGR 268 Query: 363 ISATGRGVYHGIENFIHNPDMVDKLGITPGFKDKTFIIQGFGNVGLHSMRYLVR 524 ISATGRGV+HGIENFI+ + LG+TPGF DKTF++QGFGNVGLHSMRYL R Sbjct: 269 ISATGRGVFHGIENFINEASYMSILGMTPGFGDKTFVVQGFGNVGLHSMRYLHR 322
>sp|P00367|DHE3_HUMAN Glutamate dehydrogenase 1, mitochondrial precursor (GDH) Length = 558 Score = 281 bits (719), Expect = 7e-76 Identities = 135/174 (77%), Positives = 154/174 (88%) Frame = +3 Query: 3 GIRYSMDVSKDEVKALAALMTYKCAVVDVPFGGAKAGLRIDPRLYTVGELERITRRFTVE 182 GIRYS DVS DEVKALA+LMTYKCAVVDVPFGGAKAG++I+P+ YT ELE+ITRRFT+E Sbjct: 149 GIRYSTDVSVDEVKALASLMTYKCAVVDVPFGGAKAGVKINPKNYTDNELEKITRRFTME 208 Query: 183 LAKKNFIGPGVDVPAPDMGTGEREMAWIANTFAHTRGDNDLHASACVTGKPISQGGIHGR 362 LAKK FIGPG+DVPAPDM TGEREM+WIA+T+A T G D++A ACVTGKPISQGGIHGR Sbjct: 209 LAKKGFIGPGIDVPAPDMSTGEREMSWIADTYASTIGHYDINAHACVTGKPISQGGIHGR 268 Query: 363 ISATGRGVYHGIENFIHNPDMVDKLGITPGFKDKTFIIQGFGNVGLHSMRYLVR 524 ISATGRGV+HGIENFI+ + LG+TPGF DKTF++QGFGNVGLHSMRYL R Sbjct: 269 ISATGRGVFHGIENFINEASYMSILGMTPGFGDKTFVVQGFGNVGLHSMRYLHR 322
>sp|P10860|DHE3_RAT Glutamate dehydrogenase 1, mitochondrial precursor (GDH) (Memory-related protein 2) (MRG-2) Length = 558 Score = 279 bits (713), Expect = 3e-75 Identities = 134/174 (77%), Positives = 153/174 (87%) Frame = +3 Query: 3 GIRYSMDVSKDEVKALAALMTYKCAVVDVPFGGAKAGLRIDPRLYTVGELERITRRFTVE 182 GIRYS DVS DEVKALA+LMTYKCAVVDVPFGGAKAG++I+P+ YT ELE+ITRRFT+E Sbjct: 149 GIRYSTDVSVDEVKALASLMTYKCAVVDVPFGGAKAGVKINPKNYTDNELEKITRRFTME 208 Query: 183 LAKKNFIGPGVDVPAPDMGTGEREMAWIANTFAHTRGDNDLHASACVTGKPISQGGIHGR 362 LAKK FIGPG+DVPAPDM TGEREM+WIA+T+A T G D++A ACVTGKPISQGGIHGR Sbjct: 209 LAKKGFIGPGIDVPAPDMSTGEREMSWIADTYASTIGHYDINAHACVTGKPISQGGIHGR 268 Query: 363 ISATGRGVYHGIENFIHNPDMVDKLGITPGFKDKTFIIQGFGNVGLHSMRYLVR 524 ISATGRGV+HGIENFI+ + LG+TPG DKTF++QGFGNVGLHSMRYL R Sbjct: 269 ISATGRGVFHGIENFINEASYMSILGMTPGLGDKTFVVQGFGNVGLHSMRYLHR 322
>sp|P82264|DHE3_CHAAC GLutamate dehydrogenase (GDH) Length = 504 Score = 278 bits (710), Expect = 7e-75 Identities = 132/174 (75%), Positives = 154/174 (88%) Frame = +3 Query: 3 GIRYSMDVSKDEVKALAALMTYKCAVVDVPFGGAKAGLRIDPRLYTVGELERITRRFTVE 182 GIRYSMDVS DEVKALA+LMTYKCAVVDVPFGGAKAG+RI+ + Y+ ELE+ITRRFT+E Sbjct: 95 GIRYSMDVSVDEVKALASLMTYKCAVVDVPFGGAKAGVRINTKNYSDNELEKITRRFTIE 154 Query: 183 LAKKNFIGPGVDVPAPDMGTGEREMAWIANTFAHTRGDNDLHASACVTGKPISQGGIHGR 362 LAKK FIGPG+DVPAPDM TGEREM+WIA+T+A+T D++A ACVTGKPISQGGIHGR Sbjct: 155 LAKKGFIGPGIDVPAPDMSTGEREMSWIADTYANTIAHTDINAHACVTGKPISQGGIHGR 214 Query: 363 ISATGRGVYHGIENFIHNPDMVDKLGITPGFKDKTFIIQGFGNVGLHSMRYLVR 524 ISATGRGV+HGIENF++ + +G+TPG +DKTF+IQGFGNVGLHSMRYL R Sbjct: 215 ISATGRGVFHGIENFMNEASYMSMVGLTPGVQDKTFVIQGFGNVGLHSMRYLHR 268
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 64,427,532 Number of Sequences: 369166 Number of extensions: 1384057 Number of successful extensions: 4081 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 3756 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 3931 length of database: 68,354,980 effective HSP length: 103 effective length of database: 49,327,275 effective search space used: 3502236525 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)