Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_016_N04
(200 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P11181|ODB2_BOVIN Lipoamide acyltransferase component of... 37 0.019
sp|P11182|ODB2_HUMAN Lipoamide acyltransferase component of... 36 0.032
sp|P53395|ODB2_MOUSE Lipoamide acyltransferase component of... 36 0.032
sp|Q9ZD20|ODP2_RICPR Dihydrolipoyllysine-residue acetyltran... 35 0.071
sp|P35489|ODP2_ACHLA Dihydrolipoyllysine-residue acetyltran... 32 0.60
sp|O59816|ODP2_SCHPO Dihydrolipoyllysine-residue acetyltran... 32 0.60
sp|P36413|ODP2_DICDI Dihydrolipoyllysine-residue acetyltran... 32 0.60
sp|Q92HK7|ODP2_RICCN Dihydrolipoyllysine-residue acetyltran... 31 0.78
sp|Q8BKZ9|ODPX_MOUSE Pyruvate dehydrogenase protein X compo... 30 1.7
sp|O00330|ODPX_HUMAN Pyruvate dehydrogenase protein X compo... 30 1.7
>sp|P11181|ODB2_BOVIN Lipoamide acyltransferase component of branched-chain alpha-keto
acid dehydrogenase complex, mitochondrial precursor
(Dihydrolipoyllysine-residue
(2-methylpropanoyl)transferase) (E2) (Dihydrolipoamide
branched chain transacylase) (BCKAD E2 subunit)
Length = 482
Score = 36.6 bits (83), Expect = 0.019
Identities = 18/35 (51%), Positives = 23/35 (65%)
Frame = +3
Query: 33 MRFTLCADARIIDETSASEFVSRVKSYLENPSFLL 137
M + AD RIID + S F + KSYLENP+F+L
Sbjct: 444 MNVSWSADHRIIDGATVSRFSNLWKSYLENPAFML 478
>sp|P11182|ODB2_HUMAN Lipoamide acyltransferase component of branched-chain alpha-keto
acid dehydrogenase complex, mitochondrial precursor
(Dihydrolipoyllysine-residue
(2-methylpropanoyl)transferase) (E2) (Dihydrolipoamide
branched chain transacylase) (BCKAD E2 subunit)
Length = 482
Score = 35.8 bits (81), Expect = 0.032
Identities = 17/35 (48%), Positives = 23/35 (65%)
Frame = +3
Query: 33 MRFTLCADARIIDETSASEFVSRVKSYLENPSFLL 137
M + AD R+ID + S F + KSYLENP+F+L
Sbjct: 444 MNVSWSADHRVIDGATMSRFSNLWKSYLENPAFML 478
>sp|P53395|ODB2_MOUSE Lipoamide acyltransferase component of branched-chain alpha-keto
acid dehydrogenase complex, mitochondrial precursor
(Dihydrolipoyllysine-residue
(2-methylpropanoyl)transferase) (E2) (Dihydrolipoamide
branched chain transacylase) (BCKAD E2 subunit)
Length = 482
Score = 35.8 bits (81), Expect = 0.032
Identities = 17/35 (48%), Positives = 23/35 (65%)
Frame = +3
Query: 33 MRFTLCADARIIDETSASEFVSRVKSYLENPSFLL 137
M + AD R+ID + S F + KSYLENP+F+L
Sbjct: 444 MNVSWSADHRVIDGATMSRFSNLWKSYLENPAFML 478
>sp|Q9ZD20|ODP2_RICPR Dihydrolipoyllysine-residue acetyltransferase component of pyruvate
dehydrogenase complex (E2) (Dihydrolipoamide
acetyltransferase component of pyruvate dehydrogenase
complex)
Length = 408
Score = 34.7 bits (78), Expect = 0.071
Identities = 16/37 (43%), Positives = 24/37 (64%)
Frame = +3
Query: 27 TKMRFTLCADARIIDETSASEFVSRVKSYLENPSFLL 137
T M TL AD R+ID ++EF++ K ++ENP +L
Sbjct: 371 TIMDVTLSADHRVIDGAVSAEFLASFKRFIENPVLML 407
>sp|P35489|ODP2_ACHLA Dihydrolipoyllysine-residue acetyltransferase component of pyruvate
dehydrogenase complex (E2) (Dihydrolipoamide
acetyltransferase component of pyruvate dehydrogenase
complex)
Length = 544
Score = 31.6 bits (70), Expect = 0.60
Identities = 15/32 (46%), Positives = 18/32 (56%)
Frame = +3
Query: 42 TLCADARIIDETSASEFVSRVKSYLENPSFLL 137
+L D RIID F+ RVK L NP+ LL
Sbjct: 511 SLAVDHRIIDGADGGRFLMRVKELLTNPTLLL 542
>sp|O59816|ODP2_SCHPO Dihydrolipoyllysine-residue acetyltransferase component of pyruvate
dehydrogenase complex, mitochondrial precursor (E2)
(Dihydrolipoamide acetyltransferase component of
pyruvate dehydrogenase complex) (PDC-E2)
Length = 483
Score = 31.6 bits (70), Expect = 0.60
Identities = 13/31 (41%), Positives = 20/31 (64%)
Frame = +3
Query: 33 MRFTLCADARIIDETSASEFVSRVKSYLENP 125
M+ TL +D R++D A+ F + +K LENP
Sbjct: 448 MKCTLSSDHRVVDGAMAARFTTALKKILENP 478
>sp|P36413|ODP2_DICDI Dihydrolipoyllysine-residue acetyltransferase component of pyruvate
dehydrogenase complex, mitochondrial precursor (E2)
(Dihydrolipoamide acetyltransferase component of
pyruvate dehydrogenase complex) (PDC-E2)
Length = 592
Score = 31.6 bits (70), Expect = 0.60
Identities = 16/45 (35%), Positives = 25/45 (55%), Gaps = 1/45 (2%)
Frame = +3
Query: 6 PSKP-KSVTKMRFTLCADARIIDETSASEFVSRVKSYLENPSFLL 137
P P ++ T + TL D R+ID +E++ K Y+ENP L+
Sbjct: 547 PDSPYETATILSVTLSCDHRVIDGAVGAEWLKSFKDYVENPIKLI 591
>sp|Q92HK7|ODP2_RICCN Dihydrolipoyllysine-residue acetyltransferase component of pyruvate
dehydrogenase complex (E2) (Dihydrolipoamide
acetyltransferase component of pyruvate dehydrogenase
complex)
Length = 412
Score = 31.2 bits (69), Expect = 0.78
Identities = 14/37 (37%), Positives = 22/37 (59%)
Frame = +3
Query: 27 TKMRFTLCADARIIDETSASEFVSRVKSYLENPSFLL 137
T M TL AD R++D +EF+ K ++E+P +L
Sbjct: 375 TIMDVTLSADHRVVDGAVGAEFLVAFKKFIESPVLML 411
>sp|Q8BKZ9|ODPX_MOUSE Pyruvate dehydrogenase protein X component, mitochondrial precursor
(Dihydrolipoamide dehydrogenase-binding protein of
pyruvate dehydrogenase complex) (Lipoyl-containing
pyruvate dehydrogenase complex component X)
Length = 501
Score = 30.0 bits (66), Expect = 1.7
Identities = 11/28 (39%), Positives = 20/28 (71%)
Frame = +3
Query: 42 TLCADARIIDETSASEFVSRVKSYLENP 125
T+ +D+R++D+ A+ F+ K+ LENP
Sbjct: 470 TMSSDSRVVDDELATRFLETFKANLENP 497
>sp|O00330|ODPX_HUMAN Pyruvate dehydrogenase protein X component, mitochondrial precursor
(Dihydrolipoamide dehydrogenase-binding protein of
pyruvate dehydrogenase complex) (Lipoyl-containing
pyruvate dehydrogenase complex component X) (E3-binding
protein) (E3BP) (proX)
Length = 501
Score = 30.0 bits (66), Expect = 1.7
Identities = 11/28 (39%), Positives = 20/28 (71%)
Frame = +3
Query: 42 TLCADARIIDETSASEFVSRVKSYLENP 125
T+ +D+R++D+ A+ F+ K+ LENP
Sbjct: 470 TMSSDSRVVDDELATRFLKSFKANLENP 497
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,274,345
Number of Sequences: 369166
Number of extensions: 293117
Number of successful extensions: 927
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 916
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 927
length of database: 68,354,980
effective HSP length: 38
effective length of database: 61,335,050
effective search space used: 1717381400
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)