Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_016_M18
(597 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P63331|P2AA_RAT Serine/threonine protein phosphatase 2A,... 301 1e-81
sp|P67775|P2AA_HUMAN Serine/threonine protein phosphatase 2... 301 1e-81
sp|P23696|P2A_DROME Serine/threonine protein phosphatase PP... 301 1e-81
sp|P11611|P2AB_RABIT Serine/threonine protein phosphatase 2... 300 2e-81
sp|P62714|P2AB_HUMAN Serine/threonine protein phosphatase 2... 300 2e-81
sp|P48463|P2AA_CHICK Serine/threonine protein phosphatase 2... 300 2e-81
sp|P11493|P2AB_PIG Serine/threonine protein phosphatase 2A,... 300 2e-81
sp|Q9ZSE4|P2A_HEVBR Serine/threonine protein phosphatase PP... 295 5e-80
sp|P48580|P2A1_NEUCR Serine/threonine protein phosphatase P... 295 6e-80
sp|P48579|P2A_HELAN Serine/threonine protein phosphatase PP... 295 8e-80
>sp|P63331|P2AA_RAT Serine/threonine protein phosphatase 2A, catalytic subunit, alpha
isoform (PP2A-alpha)
sp|P63330|P2AA_MOUSE Serine/threonine protein phosphatase 2A, catalytic subunit, alpha
isoform (PP2A-alpha)
Length = 309
Score = 301 bits (770), Expect = 1e-81
Identities = 141/155 (90%), Positives = 149/155 (96%)
Frame = +1
Query: 1 ILEKEGNVQLVKCPVTVCGDVHGQFHDLMELFKIGGKAPDTNYLFMGDYVDRGYYSVETV 180
IL KE NVQ V+CPVTVCGDVHGQFHDLMELF+IGGK+PDTNYLFMGDYVDRGYYSVETV
Sbjct: 38 ILTKESNVQEVRCPVTVCGDVHGQFHDLMELFRIGGKSPDTNYLFMGDYVDRGYYSVETV 97
Query: 181 TLLVALKVRYKDRITILRGNHESRQITQVYGFYDECLRKYTNANVWRYFTDLFDYLPLTA 360
TLLVALKVRY++RITILRGNHESRQITQVYGFYDECLRKY NANVW+YFTDLFDYLPLTA
Sbjct: 98 TLLVALKVRYRERITILRGNHESRQITQVYGFYDECLRKYGNANVWKYFTDLFDYLPLTA 157
Query: 361 LVESSIFCLHGGLSPSIDTLDHIRALDRIQEVPHE 465
LV+ IFCLHGGLSPSIDTLDHIRALDR+QEVPHE
Sbjct: 158 LVDGQIFCLHGGLSPSIDTLDHIRALDRLQEVPHE 192
Score = 35.4 bits (80), Expect = 0.11
Identities = 13/13 (100%), Positives = 13/13 (100%)
Frame = +3
Query: 468 PMCDLLWSDPDDR 506
PMCDLLWSDPDDR
Sbjct: 194 PMCDLLWSDPDDR 206
>sp|P67775|P2AA_HUMAN Serine/threonine protein phosphatase 2A, catalytic subunit, alpha
isoform (PP2A-alpha) (Replication protein C) (RP-C)
sp|P67774|P2AA_BOVIN Serine/threonine protein phosphatase 2A, catalytic subunit, alpha
isoform (PP2A-alpha)
sp|P67777|P2AA_RABIT Serine/threonine protein phosphatase 2A, catalytic subunit, alpha
isoform (PP2A-alpha)
sp|P67776|P2AA_PIG Serine/threonine protein phosphatase 2A, catalytic subunit, alpha
isoform (PP2A-alpha)
Length = 309
Score = 301 bits (770), Expect = 1e-81
Identities = 141/155 (90%), Positives = 149/155 (96%)
Frame = +1
Query: 1 ILEKEGNVQLVKCPVTVCGDVHGQFHDLMELFKIGGKAPDTNYLFMGDYVDRGYYSVETV 180
IL KE NVQ V+CPVTVCGDVHGQFHDLMELF+IGGK+PDTNYLFMGDYVDRGYYSVETV
Sbjct: 38 ILTKESNVQEVRCPVTVCGDVHGQFHDLMELFRIGGKSPDTNYLFMGDYVDRGYYSVETV 97
Query: 181 TLLVALKVRYKDRITILRGNHESRQITQVYGFYDECLRKYTNANVWRYFTDLFDYLPLTA 360
TLLVALKVRY++RITILRGNHESRQITQVYGFYDECLRKY NANVW+YFTDLFDYLPLTA
Sbjct: 98 TLLVALKVRYRERITILRGNHESRQITQVYGFYDECLRKYGNANVWKYFTDLFDYLPLTA 157
Query: 361 LVESSIFCLHGGLSPSIDTLDHIRALDRIQEVPHE 465
LV+ IFCLHGGLSPSIDTLDHIRALDR+QEVPHE
Sbjct: 158 LVDGQIFCLHGGLSPSIDTLDHIRALDRLQEVPHE 192
Score = 35.4 bits (80), Expect = 0.11
Identities = 13/13 (100%), Positives = 13/13 (100%)
Frame = +3
Query: 468 PMCDLLWSDPDDR 506
PMCDLLWSDPDDR
Sbjct: 194 PMCDLLWSDPDDR 206
>sp|P23696|P2A_DROME Serine/threonine protein phosphatase PP2A (Microtubule star
protein)
Length = 309
Score = 301 bits (770), Expect = 1e-81
Identities = 141/155 (90%), Positives = 149/155 (96%)
Frame = +1
Query: 1 ILEKEGNVQLVKCPVTVCGDVHGQFHDLMELFKIGGKAPDTNYLFMGDYVDRGYYSVETV 180
IL KE NVQ VKCPVTVCGDVHGQFHDLMELF+IGGK+PDTNYLFMGDYVDRGYYSVETV
Sbjct: 38 ILSKESNVQEVKCPVTVCGDVHGQFHDLMELFRIGGKSPDTNYLFMGDYVDRGYYSVETV 97
Query: 181 TLLVALKVRYKDRITILRGNHESRQITQVYGFYDECLRKYTNANVWRYFTDLFDYLPLTA 360
TLLVALKVRY++RITILRGNHESRQITQVYGFYDECLRKY NANVW+YFTDLFDYLPLTA
Sbjct: 98 TLLVALKVRYRERITILRGNHESRQITQVYGFYDECLRKYGNANVWKYFTDLFDYLPLTA 157
Query: 361 LVESSIFCLHGGLSPSIDTLDHIRALDRIQEVPHE 465
LV+ IFCLHGGLSPSID+LDHIRALDR+QEVPHE
Sbjct: 158 LVDGQIFCLHGGLSPSIDSLDHIRALDRLQEVPHE 192
Score = 35.4 bits (80), Expect = 0.11
Identities = 13/13 (100%), Positives = 13/13 (100%)
Frame = +3
Query: 468 PMCDLLWSDPDDR 506
PMCDLLWSDPDDR
Sbjct: 194 PMCDLLWSDPDDR 206
>sp|P11611|P2AB_RABIT Serine/threonine protein phosphatase 2A, catalytic subunit, beta
isoform (PP2A-beta)
Length = 309
Score = 300 bits (767), Expect = 2e-81
Identities = 141/155 (90%), Positives = 148/155 (95%)
Frame = +1
Query: 1 ILEKEGNVQLVKCPVTVCGDVHGQFHDLMELFKIGGKAPDTNYLFMGDYVDRGYYSVETV 180
IL KE NVQ V+CPVTVCGDVHGQFHDLMELF+IGGK+PDTNYLFMGDYVDRGYYSVETV
Sbjct: 38 ILTKESNVQEVRCPVTVCGDVHGQFHDLMELFRIGGKSPDTNYLFMGDYVDRGYYSVETV 97
Query: 181 TLLVALKVRYKDRITILRGNHESRQITQVYGFYDECLRKYTNANVWRYFTDLFDYLPLTA 360
TLLVALKVRY +RITILRGNHESRQITQVYGFYDECLRKY NANVW+YFTDLFDYLPLTA
Sbjct: 98 TLLVALKVRYPERITILRGNHESRQITQVYGFYDECLRKYGNANVWKYFTDLFDYLPLTA 157
Query: 361 LVESSIFCLHGGLSPSIDTLDHIRALDRIQEVPHE 465
LV+ IFCLHGGLSPSIDTLDHIRALDR+QEVPHE
Sbjct: 158 LVDGQIFCLHGGLSPSIDTLDHIRALDRLQEVPHE 192
Score = 35.4 bits (80), Expect = 0.11
Identities = 13/13 (100%), Positives = 13/13 (100%)
Frame = +3
Query: 468 PMCDLLWSDPDDR 506
PMCDLLWSDPDDR
Sbjct: 194 PMCDLLWSDPDDR 206
>sp|P62714|P2AB_HUMAN Serine/threonine protein phosphatase 2A, catalytic subunit, beta
isoform (PP2A-beta)
sp|P62716|P2AB_RAT Serine/threonine protein phosphatase 2A, catalytic subunit, beta
isoform (PP2A-beta)
sp|P62715|P2AB_MOUSE Serine/threonine protein phosphatase 2A, catalytic subunit, beta
isoform (PP2A-beta)
Length = 309
Score = 300 bits (767), Expect = 2e-81
Identities = 141/155 (90%), Positives = 148/155 (95%)
Frame = +1
Query: 1 ILEKEGNVQLVKCPVTVCGDVHGQFHDLMELFKIGGKAPDTNYLFMGDYVDRGYYSVETV 180
IL KE NVQ V+CPVTVCGDVHGQFHDLMELF+IGGK+PDTNYLFMGDYVDRGYYSVETV
Sbjct: 38 ILTKESNVQEVRCPVTVCGDVHGQFHDLMELFRIGGKSPDTNYLFMGDYVDRGYYSVETV 97
Query: 181 TLLVALKVRYKDRITILRGNHESRQITQVYGFYDECLRKYTNANVWRYFTDLFDYLPLTA 360
TLLVALKVRY +RITILRGNHESRQITQVYGFYDECLRKY NANVW+YFTDLFDYLPLTA
Sbjct: 98 TLLVALKVRYPERITILRGNHESRQITQVYGFYDECLRKYGNANVWKYFTDLFDYLPLTA 157
Query: 361 LVESSIFCLHGGLSPSIDTLDHIRALDRIQEVPHE 465
LV+ IFCLHGGLSPSIDTLDHIRALDR+QEVPHE
Sbjct: 158 LVDGQIFCLHGGLSPSIDTLDHIRALDRLQEVPHE 192
Score = 35.4 bits (80), Expect = 0.11
Identities = 13/13 (100%), Positives = 13/13 (100%)
Frame = +3
Query: 468 PMCDLLWSDPDDR 506
PMCDLLWSDPDDR
Sbjct: 194 PMCDLLWSDPDDR 206
>sp|P48463|P2AA_CHICK Serine/threonine protein phosphatase 2A, catalytic subunit, alpha
isoform (PP2A-alpha)
Length = 309
Score = 300 bits (767), Expect = 2e-81
Identities = 141/155 (90%), Positives = 148/155 (95%)
Frame = +1
Query: 1 ILEKEGNVQLVKCPVTVCGDVHGQFHDLMELFKIGGKAPDTNYLFMGDYVDRGYYSVETV 180
IL KE NVQ V+CPVTVCGDVHGQFHDLMELF+IGGK+PDTNYLFMGDYVDRGYYSVETV
Sbjct: 38 ILTKESNVQEVRCPVTVCGDVHGQFHDLMELFRIGGKSPDTNYLFMGDYVDRGYYSVETV 97
Query: 181 TLLVALKVRYKDRITILRGNHESRQITQVYGFYDECLRKYTNANVWRYFTDLFDYLPLTA 360
TLLVALKVRY +RITILRGNHESRQITQVYGFYDECLRKY NANVW+YFTDLFDYLPLTA
Sbjct: 98 TLLVALKVRYPERITILRGNHESRQITQVYGFYDECLRKYGNANVWKYFTDLFDYLPLTA 157
Query: 361 LVESSIFCLHGGLSPSIDTLDHIRALDRIQEVPHE 465
LV+ IFCLHGGLSPSIDTLDHIRALDR+QEVPHE
Sbjct: 158 LVDGQIFCLHGGLSPSIDTLDHIRALDRLQEVPHE 192
Score = 35.4 bits (80), Expect = 0.11
Identities = 13/13 (100%), Positives = 13/13 (100%)
Frame = +3
Query: 468 PMCDLLWSDPDDR 506
PMCDLLWSDPDDR
Sbjct: 194 PMCDLLWSDPDDR 206
>sp|P11493|P2AB_PIG Serine/threonine protein phosphatase 2A, catalytic subunit, beta
isoform (PP2A-beta)
Length = 293
Score = 300 bits (767), Expect = 2e-81
Identities = 141/155 (90%), Positives = 148/155 (95%)
Frame = +1
Query: 1 ILEKEGNVQLVKCPVTVCGDVHGQFHDLMELFKIGGKAPDTNYLFMGDYVDRGYYSVETV 180
IL KE NVQ V+CPVTVCGDVHGQFHDLMELF+IGGK+PDTNYLFMGDYVDRGYYSVETV
Sbjct: 22 ILTKESNVQEVRCPVTVCGDVHGQFHDLMELFRIGGKSPDTNYLFMGDYVDRGYYSVETV 81
Query: 181 TLLVALKVRYKDRITILRGNHESRQITQVYGFYDECLRKYTNANVWRYFTDLFDYLPLTA 360
TLLVALKVRY +RITILRGNHESRQITQVYGFYDECLRKY NANVW+YFTDLFDYLPLTA
Sbjct: 82 TLLVALKVRYPERITILRGNHESRQITQVYGFYDECLRKYGNANVWKYFTDLFDYLPLTA 141
Query: 361 LVESSIFCLHGGLSPSIDTLDHIRALDRIQEVPHE 465
LV+ IFCLHGGLSPSIDTLDHIRALDR+QEVPHE
Sbjct: 142 LVDGQIFCLHGGLSPSIDTLDHIRALDRLQEVPHE 176
Score = 35.4 bits (80), Expect = 0.11
Identities = 13/13 (100%), Positives = 13/13 (100%)
Frame = +3
Query: 468 PMCDLLWSDPDDR 506
PMCDLLWSDPDDR
Sbjct: 178 PMCDLLWSDPDDR 190
>sp|Q9ZSE4|P2A_HEVBR Serine/threonine protein phosphatase PP2A catalytic subunit
Length = 306
Score = 295 bits (756), Expect = 5e-80
Identities = 139/155 (89%), Positives = 149/155 (96%)
Frame = +1
Query: 1 ILEKEGNVQLVKCPVTVCGDVHGQFHDLMELFKIGGKAPDTNYLFMGDYVDRGYYSVETV 180
IL +E NVQ VKCPVTVCGD+HGQF+DL+ELF+IGG APDTNYLFMGDYVDRGYYSVETV
Sbjct: 35 ILVEEWNVQPVKCPVTVCGDIHGQFYDLIELFRIGGNAPDTNYLFMGDYVDRGYYSVETV 94
Query: 181 TLLVALKVRYKDRITILRGNHESRQITQVYGFYDECLRKYTNANVWRYFTDLFDYLPLTA 360
TLLVALKVRY+DRITILRGNHESRQITQVYGFYDECLRKY NANVW+YFTDLFDYLPLTA
Sbjct: 95 TLLVALKVRYRDRITILRGNHESRQITQVYGFYDECLRKYGNANVWKYFTDLFDYLPLTA 154
Query: 361 LVESSIFCLHGGLSPSIDTLDHIRALDRIQEVPHE 465
L+ES IFCLHGGLSPS+DTLD+IRALDRIQEVPHE
Sbjct: 155 LIESQIFCLHGGLSPSLDTLDNIRALDRIQEVPHE 189
Score = 35.4 bits (80), Expect = 0.11
Identities = 13/13 (100%), Positives = 13/13 (100%)
Frame = +3
Query: 468 PMCDLLWSDPDDR 506
PMCDLLWSDPDDR
Sbjct: 191 PMCDLLWSDPDDR 203
>sp|P48580|P2A1_NEUCR Serine/threonine protein phosphatase PP2A catalytic subunit
Length = 327
Score = 295 bits (755), Expect = 6e-80
Identities = 137/155 (88%), Positives = 147/155 (94%)
Frame = +1
Query: 1 ILEKEGNVQLVKCPVTVCGDVHGQFHDLMELFKIGGKAPDTNYLFMGDYVDRGYYSVETV 180
+L+ E NVQ VKCPVTVCGD+HGQFHDLMELFKIGG PDTNYLFMGDYVDRGYYSVETV
Sbjct: 56 VLQDESNVQPVKCPVTVCGDIHGQFHDLMELFKIGGSCPDTNYLFMGDYVDRGYYSVETV 115
Query: 181 TLLVALKVRYKDRITILRGNHESRQITQVYGFYDECLRKYTNANVWRYFTDLFDYLPLTA 360
TLLVALK+RY +RITILRGNHESRQITQVYGFYDECLRKY NANVW+YFTDLFDYLPLTA
Sbjct: 116 TLLVALKIRYPNRITILRGNHESRQITQVYGFYDECLRKYGNANVWKYFTDLFDYLPLTA 175
Query: 361 LVESSIFCLHGGLSPSIDTLDHIRALDRIQEVPHE 465
L+++ IFCLHGGLSPSIDTLD+IRALDRIQEVPHE
Sbjct: 176 LIDNQIFCLHGGLSPSIDTLDNIRALDRIQEVPHE 210
Score = 35.4 bits (80), Expect = 0.11
Identities = 13/13 (100%), Positives = 13/13 (100%)
Frame = +3
Query: 468 PMCDLLWSDPDDR 506
PMCDLLWSDPDDR
Sbjct: 212 PMCDLLWSDPDDR 224
>sp|P48579|P2A_HELAN Serine/threonine protein phosphatase PP2A catalytic subunit
Length = 305
Score = 295 bits (754), Expect = 8e-80
Identities = 138/155 (89%), Positives = 149/155 (96%)
Frame = +1
Query: 1 ILEKEGNVQLVKCPVTVCGDVHGQFHDLMELFKIGGKAPDTNYLFMGDYVDRGYYSVETV 180
IL +E NVQ VKCPVTVCGD+HGQFHDL+ELF+IGG APDTNYLFMGDYVDRGYYSVETV
Sbjct: 34 ILVEEWNVQPVKCPVTVCGDIHGQFHDLLELFRIGGSAPDTNYLFMGDYVDRGYYSVETV 93
Query: 181 TLLVALKVRYKDRITILRGNHESRQITQVYGFYDECLRKYTNANVWRYFTDLFDYLPLTA 360
TLLVALKVRY+DRITILRGNHESRQITQVYGF+DECLRKY NANVW++FTDLFDYLPLTA
Sbjct: 94 TLLVALKVRYRDRITILRGNHESRQITQVYGFFDECLRKYGNANVWKHFTDLFDYLPLTA 153
Query: 361 LVESSIFCLHGGLSPSIDTLDHIRALDRIQEVPHE 465
L+ES IFCLHGGLSPS+DTLD+IRALDRIQEVPHE
Sbjct: 154 LIESQIFCLHGGLSPSLDTLDNIRALDRIQEVPHE 188
Score = 35.4 bits (80), Expect = 0.11
Identities = 13/13 (100%), Positives = 13/13 (100%)
Frame = +3
Query: 468 PMCDLLWSDPDDR 506
PMCDLLWSDPDDR
Sbjct: 190 PMCDLLWSDPDDR 202
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 62,481,689
Number of Sequences: 369166
Number of extensions: 1152333
Number of successful extensions: 3260
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 2965
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3163
length of database: 68,354,980
effective HSP length: 105
effective length of database: 48,957,805
effective search space used: 4553075865
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)