Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= Dr_sW_016_M09 (318 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|P27797|CRTC_HUMAN Calreticulin precursor (CRP55) (Calreg... 77 1e-14 sp|P42918|CRTC2_BOVIN Calreticulin, brain isoform 2 precurs... 75 6e-14 sp|P52193|CRTC1_BOVIN Calreticulin, brain isoform 1 precurs... 75 6e-14 sp|P18418|CRTC_RAT Calreticulin precursor (CRP55) (Calregul... 73 2e-13 sp|P14211|CRTC_MOUSE Calreticulin precursor (CRP55) (Calreg... 73 2e-13 sp|Q8K3H7|CRTC_CRIGR Calreticulin precursor (CRP55) (Calreg... 73 2e-13 sp|P15253|CRTC_RABIT Calreticulin precursor (CRP55) (Calreg... 72 5e-13 sp|Q9D9Q6|CRTC3_MOUSE Calreticulin-3 precursor (Calreticuli... 69 3e-12 sp|P11012|RAL1_ONCVO RAL-1 protein precursor (RAL1 antigen)... 67 2e-11 sp|P29413|CRTC_DROME Calreticulin precursor (CRP55) (Calreg... 66 2e-11
>sp|P27797|CRTC_HUMAN Calreticulin precursor (CRP55) (Calregulin) (HACBP) (ERp60) (grp60) Length = 417 Score = 77.0 bits (188), Expect = 1e-14 Identities = 34/53 (64%), Positives = 42/53 (79%) Frame = +1 Query: 103 NIGSIGFDLWQVKSGTIFDNILLTDDPAYAKKYVEKTWKETAAGEKKMKDKQD 261 N G +G DLWQVKSGTIFDN L+T+D AYA+++ +TW T A EK+MKDKQD Sbjct: 310 NFGVLGLDLWQVKSGTIFDNFLITNDEAYAEEFGNETWGVTKAAEKQMKDKQD 362
Score = 54.7 bits (130), Expect = 7e-08 Identities = 20/27 (74%), Positives = 24/27 (88%) Frame = +2 Query: 2 EPKQIDNPKYKGPWIHPEIDNPDYKPE 82 +P+QIDNP YKG WIHPEIDNP+Y P+ Sbjct: 276 KPRQIDNPDYKGTWIHPEIDNPEYSPD 302
>sp|P42918|CRTC2_BOVIN Calreticulin, brain isoform 2 precursor (CRP55) (Calregulin) (HACBP) Length = 421 Score = 74.7 bits (182), Expect = 6e-14 Identities = 33/53 (62%), Positives = 41/53 (77%) Frame = +1 Query: 103 NIGSIGFDLWQVKSGTIFDNILLTDDPAYAKKYVEKTWKETAAGEKKMKDKQD 261 N +G DLWQVKSGTIFDN L+T+D AYA+++ +TW T A EK+MKDKQD Sbjct: 314 NFAVLGLDLWQVKSGTIFDNFLITNDEAYAEEFGNETWGVTKAAEKQMKDKQD 366
Score = 58.5 bits (140), Expect = 5e-09 Identities = 22/29 (75%), Positives = 27/29 (93%) Frame = +2 Query: 2 EPKQIDNPKYKGPWIHPEIDNPDYKPESN 88 +P+QIDNP+YKG WIHPEIDNP+Y P+SN Sbjct: 280 KPRQIDNPEYKGIWIHPEIDNPEYSPDSN 308
>sp|P52193|CRTC1_BOVIN Calreticulin, brain isoform 1 precursor (CRP55) (Calregulin) (HACBP) Length = 417 Score = 74.7 bits (182), Expect = 6e-14 Identities = 33/53 (62%), Positives = 41/53 (77%) Frame = +1 Query: 103 NIGSIGFDLWQVKSGTIFDNILLTDDPAYAKKYVEKTWKETAAGEKKMKDKQD 261 N +G DLWQVKSGTIFDN L+T+D AYA+++ +TW T A EK+MKDKQD Sbjct: 310 NFAVLGLDLWQVKSGTIFDNFLITNDEAYAEEFGNETWGVTKAAEKQMKDKQD 362
Score = 58.5 bits (140), Expect = 5e-09 Identities = 22/29 (75%), Positives = 27/29 (93%) Frame = +2 Query: 2 EPKQIDNPKYKGPWIHPEIDNPDYKPESN 88 +P+QIDNP+YKG WIHPEIDNP+Y P+SN Sbjct: 276 KPRQIDNPEYKGIWIHPEIDNPEYSPDSN 304
>sp|P18418|CRTC_RAT Calreticulin precursor (CRP55) (Calregulin) (HACBP) (ERp60) (CALBP) (Calcium-binding protein 3) (CABP3) Length = 416 Score = 73.2 bits (178), Expect = 2e-13 Identities = 32/49 (65%), Positives = 40/49 (81%) Frame = +1 Query: 115 IGFDLWQVKSGTIFDNILLTDDPAYAKKYVEKTWKETAAGEKKMKDKQD 261 +G DLWQVKSGTIFDN L+T+D AYA+++ +TW T A EK+MKDKQD Sbjct: 314 LGLDLWQVKSGTIFDNFLITNDEAYAEEFGNETWGVTKAAEKQMKDKQD 362
Score = 57.4 bits (137), Expect = 1e-08 Identities = 21/29 (72%), Positives = 26/29 (89%) Frame = +2 Query: 2 EPKQIDNPKYKGPWIHPEIDNPDYKPESN 88 +P+QIDNP YKG WIHPEIDNP+Y P++N Sbjct: 276 KPRQIDNPDYKGTWIHPEIDNPEYSPDAN 304
>sp|P14211|CRTC_MOUSE Calreticulin precursor (CRP55) (Calregulin) (HACBP) (ERp60) Length = 416 Score = 73.2 bits (178), Expect = 2e-13 Identities = 32/49 (65%), Positives = 40/49 (81%) Frame = +1 Query: 115 IGFDLWQVKSGTIFDNILLTDDPAYAKKYVEKTWKETAAGEKKMKDKQD 261 +G DLWQVKSGTIFDN L+T+D AYA+++ +TW T A EK+MKDKQD Sbjct: 314 LGLDLWQVKSGTIFDNFLITNDEAYAEEFGNETWGVTKAAEKQMKDKQD 362
Score = 57.4 bits (137), Expect = 1e-08 Identities = 21/29 (72%), Positives = 26/29 (89%) Frame = +2 Query: 2 EPKQIDNPKYKGPWIHPEIDNPDYKPESN 88 +P+QIDNP YKG WIHPEIDNP+Y P++N Sbjct: 276 KPRQIDNPDYKGTWIHPEIDNPEYSPDAN 304
>sp|Q8K3H7|CRTC_CRIGR Calreticulin precursor (CRP55) (Calregulin) (HACBP) (ERp60) Length = 417 Score = 73.2 bits (178), Expect = 2e-13 Identities = 32/49 (65%), Positives = 40/49 (81%) Frame = +1 Query: 115 IGFDLWQVKSGTIFDNILLTDDPAYAKKYVEKTWKETAAGEKKMKDKQD 261 +G DLWQVKSGTIFDN L+T+D AYA+++ +TW T A EK+MKDKQD Sbjct: 314 LGLDLWQVKSGTIFDNFLITNDEAYAEEFGNETWGVTKASEKQMKDKQD 362
Score = 57.4 bits (137), Expect = 1e-08 Identities = 21/29 (72%), Positives = 26/29 (89%) Frame = +2 Query: 2 EPKQIDNPKYKGPWIHPEIDNPDYKPESN 88 +P+QIDNP YKG WIHPEIDNP+Y P++N Sbjct: 276 KPRQIDNPDYKGTWIHPEIDNPEYSPDAN 304
>sp|P15253|CRTC_RABIT Calreticulin precursor (CRP55) (Calregulin) (HACBP) (ERp60) Length = 418 Score = 71.6 bits (174), Expect = 5e-13 Identities = 31/49 (63%), Positives = 39/49 (79%) Frame = +1 Query: 115 IGFDLWQVKSGTIFDNILLTDDPAYAKKYVEKTWKETAAGEKKMKDKQD 261 +G DLWQVKSGTIFDN L+T+D AYA+++ +TW T EK+MKDKQD Sbjct: 314 LGLDLWQVKSGTIFDNFLITNDEAYAEEFGNETWGVTKTAEKQMKDKQD 362
Score = 57.4 bits (137), Expect = 1e-08 Identities = 21/29 (72%), Positives = 26/29 (89%) Frame = +2 Query: 2 EPKQIDNPKYKGPWIHPEIDNPDYKPESN 88 +P+QIDNP YKG WIHPEIDNP+Y P++N Sbjct: 276 KPRQIDNPDYKGTWIHPEIDNPEYSPDAN 304
>sp|Q9D9Q6|CRTC3_MOUSE Calreticulin-3 precursor (Calreticulin-2) Length = 380 Score = 68.9 bits (167), Expect = 3e-12 Identities = 30/48 (62%), Positives = 38/48 (79%) Frame = +1 Query: 103 NIGSIGFDLWQVKSGTIFDNILLTDDPAYAKKYVEKTWKETAAGEKKM 246 NIG+IG +LWQV+SGTIFDN L+TDD YA+K+ + TW ET EK+M Sbjct: 293 NIGAIGLELWQVRSGTIFDNFLITDDEEYAEKFGKATWGETKGPEKEM 340
>sp|P11012|RAL1_ONCVO RAL-1 protein precursor (RAL1 antigen) (41 kDa larval antigen) Length = 388 Score = 66.6 bits (161), Expect = 2e-11 Identities = 32/51 (62%), Positives = 39/51 (76%) Frame = +1 Query: 103 NIGSIGFDLWQVKSGTIFDNILLTDDPAYAKKYVEKTWKETAAGEKKMKDK 255 +IG+IGFDLWQVKSGTIFD++++TD AKK+ EKT K T GEKK K Sbjct: 308 DIGAIGFDLWQVKSGTIFDDVIVTDSVEEAKKFGEKTLKITREGEKKKGKK 358
Score = 48.9 bits (115), Expect = 4e-06 Identities = 19/29 (65%), Positives = 22/29 (75%) Frame = +2 Query: 2 EPKQIDNPKYKGPWIHPEIDNPDYKPESN 88 +PKQ NP YKG WIHPEI+ PDY P+ N Sbjct: 274 KPKQKKNPAYKGKWIHPEIEIPDYTPDDN 302
>sp|P29413|CRTC_DROME Calreticulin precursor (CRP55) (Calregulin) (HACBP) Length = 406 Score = 66.2 bits (160), Expect = 2e-11 Identities = 33/52 (63%), Positives = 39/52 (75%) Frame = +1 Query: 106 IGSIGFDLWQVKSGTIFDNILLTDDPAYAKKYVEKTWKETAAGEKKMKDKQD 261 I ++GFDLWQVKSGTIFDN+L+TDD A K + K T AGEKKMK+ QD Sbjct: 311 ICTLGFDLWQVKSGTIFDNVLITDDVELAAKAAAEV-KNTQAGEKKMKEAQD 361
Score = 49.3 bits (116), Expect = 3e-06 Identities = 18/27 (66%), Positives = 22/27 (81%) Frame = +2 Query: 2 EPKQIDNPKYKGPWIHPEIDNPDYKPE 82 +PKQ+DNP YKG W HPEI NP+Y P+ Sbjct: 276 QPKQLDNPNYKGAWEHPEIANPEYVPD 302
Score = 38.9 bits (89), Expect = 0.004 Identities = 14/25 (56%), Positives = 19/25 (76%) Frame = +2 Query: 2 EPKQIDNPKYKGPWIHPEIDNPDYK 76 EP IDNP++KG W ++DNP+YK Sbjct: 262 EPPMIDNPEFKGEWQPKQLDNPNYK 286
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 28,809,263 Number of Sequences: 369166 Number of extensions: 437117 Number of successful extensions: 1462 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 1325 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 1461 length of database: 68,354,980 effective HSP length: 74 effective length of database: 54,684,590 effective search space used: 1695222290 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)