Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= Dr_sW_016_M05 (744 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|Q03265|ATPA_MOUSE ATP synthase alpha chain, mitochondria... 383 e-106 sp|P19483|ATPA1_BOVIN ATP synthase alpha chain heart isofor... 383 e-106 sp|P15999|ATPA_RAT ATP synthase alpha chain, mitochondrial ... 383 e-106 sp|P35381|ATPA_DROME ATP synthase alpha chain, mitochondria... 382 e-106 sp|P25705|ATPA_HUMAN ATP synthase alpha chain, mitochondria... 382 e-106 sp|P08428|ATPA_XENLA ATP synthase alpha chain, mitochondria... 380 e-105 sp|P49375|ATPA_KLULA ATP synthase alpha chain, mitochondria... 325 6e-89 sp|P24487|ATPA_SCHPO ATP synthase alpha chain, mitochondria... 322 9e-88 sp|P37211|ATPA_NEUCR ATP synthase alpha chain, mitochondria... 320 3e-87 sp|P07251|ATPA_YEAST ATP synthase alpha chain, mitochondria... 320 3e-87
>sp|Q03265|ATPA_MOUSE ATP synthase alpha chain, mitochondrial precursor Length = 553 Score = 383 bits (984), Expect = e-106 Identities = 195/229 (85%), Positives = 213/229 (93%) Frame = +3 Query: 6 MSLLLRRPPGREAYPGDVFYLHSRLLERAAKMSDVYGGGSLTALPVIETQAGDVSAYIPT 185 MSLLLRRPPGREAYPGDVFYLHSRLLERAAKM+D +GGGSLTALPVIETQAGDVSAYIPT Sbjct: 324 MSLLLRRPPGREAYPGDVFYLHSRLLERAAKMNDSFGGGSLTALPVIETQAGDVSAYIPT 383 Query: 186 NVISITDGQIFLETELFYKGIRPAINVGLSVSRVGSAAQTKAMKQVAGRMKLELAQYREV 365 NVISITDGQIFLETELFYKGIRPAINVGLSVSRVGSAAQT+AMKQVAG MKLELAQYREV Sbjct: 384 NVISITDGQIFLETELFYKGIRPAINVGLSVSRVGSAAQTRAMKQVAGTMKLELAQYREV 443 Query: 366 AAFAQFGSDLDASTQQLLNRGVRLTELLKQGQYVPMAIEDQIVVIYAGVRGYLDKMDPSK 545 AAFAQFGSDLDA+TQQLL+RGVRLTELLKQGQY PMAIE+Q+ VIYAGVRGYLDK++PSK Sbjct: 444 AAFAQFGSDLDAATQQLLSRGVRLTELLKQGQYSPMAIEEQVAVIYAGVRGYLDKLEPSK 503 Query: 546 ITKFEQEYLKNVLVNHQDLLKDIRESGVISEANDAKMKKIVTDFVASFE 692 ITKFE +L +V+ HQ LL +IR G ISE +DAK+K+IVT+F+A FE Sbjct: 504 ITKFENAFLSHVISQHQSLLGNIRSDGKISEQSDAKLKEIVTNFLAGFE 552
>sp|P19483|ATPA1_BOVIN ATP synthase alpha chain heart isoform, mitochondrial precursor Length = 553 Score = 383 bits (983), Expect = e-106 Identities = 195/229 (85%), Positives = 212/229 (92%) Frame = +3 Query: 6 MSLLLRRPPGREAYPGDVFYLHSRLLERAAKMSDVYGGGSLTALPVIETQAGDVSAYIPT 185 MSLLLRRPPGREAYPGDVFYLHSRLLERAAKM+D +GGGSLTALPVIETQAGDVSAYIPT Sbjct: 324 MSLLLRRPPGREAYPGDVFYLHSRLLERAAKMNDAFGGGSLTALPVIETQAGDVSAYIPT 383 Query: 186 NVISITDGQIFLETELFYKGIRPAINVGLSVSRVGSAAQTKAMKQVAGRMKLELAQYREV 365 NVISITDGQIFLETELFYKGIRPAINVGLSVSRVGSAAQT+AMKQVAG MKLELAQYREV Sbjct: 384 NVISITDGQIFLETELFYKGIRPAINVGLSVSRVGSAAQTRAMKQVAGTMKLELAQYREV 443 Query: 366 AAFAQFGSDLDASTQQLLNRGVRLTELLKQGQYVPMAIEDQIVVIYAGVRGYLDKMDPSK 545 AAFAQFGSDLDA+TQQLL+RGVRLTELLKQGQY PMAIE+Q+ VIYAGVRGYLDK++PSK Sbjct: 444 AAFAQFGSDLDAATQQLLSRGVRLTELLKQGQYSPMAIEEQVAVIYAGVRGYLDKLEPSK 503 Query: 546 ITKFEQEYLKNVLVNHQDLLKDIRESGVISEANDAKMKKIVTDFVASFE 692 ITKFE +L +V+ HQ LL IR G ISE +DAK+K+IVT+F+A FE Sbjct: 504 ITKFENAFLSHVISQHQALLSKIRTDGKISEESDAKLKEIVTNFLAGFE 552
>sp|P15999|ATPA_RAT ATP synthase alpha chain, mitochondrial precursor Length = 543 Score = 383 bits (983), Expect = e-106 Identities = 195/229 (85%), Positives = 213/229 (93%) Frame = +3 Query: 6 MSLLLRRPPGREAYPGDVFYLHSRLLERAAKMSDVYGGGSLTALPVIETQAGDVSAYIPT 185 MSLLLRRPPGREAYPGDVFYLHSRLLERAAKM+D +GGGSLTALPVIETQAGDVSAYIPT Sbjct: 314 MSLLLRRPPGREAYPGDVFYLHSRLLERAAKMNDSFGGGSLTALPVIETQAGDVSAYIPT 373 Query: 186 NVISITDGQIFLETELFYKGIRPAINVGLSVSRVGSAAQTKAMKQVAGRMKLELAQYREV 365 NVISITDGQIFLETELFYKGIRPAINVGLSVSRVGSAAQT+AMKQVAG MKLELAQYREV Sbjct: 374 NVISITDGQIFLETELFYKGIRPAINVGLSVSRVGSAAQTRAMKQVAGTMKLELAQYREV 433 Query: 366 AAFAQFGSDLDASTQQLLNRGVRLTELLKQGQYVPMAIEDQIVVIYAGVRGYLDKMDPSK 545 AAFAQFGSDLDA+TQQLL+RGVRLTELLKQGQY PMAIE+Q+ VIYAGVRGYLDK++PSK Sbjct: 434 AAFAQFGSDLDAATQQLLSRGVRLTELLKQGQYSPMAIEEQVAVIYAGVRGYLDKLEPSK 493 Query: 546 ITKFEQEYLKNVLVNHQDLLKDIRESGVISEANDAKMKKIVTDFVASFE 692 ITKFE +L +V+ HQ LL +IR G ISE +DAK+K+IVT+F+A FE Sbjct: 494 ITKFESAFLSHVVSQHQSLLGNIRSDGKISEQSDAKLKEIVTNFLAGFE 542
>sp|P35381|ATPA_DROME ATP synthase alpha chain, mitochondrial precursor (Protein bellwether) Length = 552 Score = 382 bits (980), Expect = e-106 Identities = 195/230 (84%), Positives = 212/230 (92%) Frame = +3 Query: 6 MSLLLRRPPGREAYPGDVFYLHSRLLERAAKMSDVYGGGSLTALPVIETQAGDVSAYIPT 185 MSLLLRRPPGREAYPGDVFYLHSRLLERAAKMS GGGSLTALPVIETQAGDVSAYIPT Sbjct: 323 MSLLLRRPPGREAYPGDVFYLHSRLLERAAKMSPAMGGGSLTALPVIETQAGDVSAYIPT 382 Query: 186 NVISITDGQIFLETELFYKGIRPAINVGLSVSRVGSAAQTKAMKQVAGRMKLELAQYREV 365 NVISITDGQIFLETELFYKGIRPAINVGLSVSRVGSAAQTKAMKQVAG MKLELAQYREV Sbjct: 383 NVISITDGQIFLETELFYKGIRPAINVGLSVSRVGSAAQTKAMKQVAGSMKLELAQYREV 442 Query: 366 AAFAQFGSDLDASTQQLLNRGVRLTELLKQGQYVPMAIEDQIVVIYAGVRGYLDKMDPSK 545 AAFAQFGSDLDA+TQQLLNRGVRLTELLKQGQYVPMAIEDQ+ VIY GVRG+LDKMDP+K Sbjct: 443 AAFAQFGSDLDAATQQLLNRGVRLTELLKQGQYVPMAIEDQVAVIYCGVRGHLDKMDPAK 502 Query: 546 ITKFEQEYLKNVLVNHQDLLKDIRESGVISEANDAKMKKIVTDFVASFEG 695 ITKFE+E+L+++ + Q LL I + G ISEA+DAK+K IV F+++F+G Sbjct: 503 ITKFEKEFLQHIKTSEQALLDTIAKDGAISEASDAKLKDIVAKFMSTFQG 552
>sp|P25705|ATPA_HUMAN ATP synthase alpha chain, mitochondrial precursor Length = 553 Score = 382 bits (980), Expect = e-106 Identities = 195/229 (85%), Positives = 212/229 (92%) Frame = +3 Query: 6 MSLLLRRPPGREAYPGDVFYLHSRLLERAAKMSDVYGGGSLTALPVIETQAGDVSAYIPT 185 MSLLLRRPPGREAYPGDVFYLHSRLLERAAKM+D +GGGSLTALPVIETQAGDVSAYIPT Sbjct: 324 MSLLLRRPPGREAYPGDVFYLHSRLLERAAKMNDAFGGGSLTALPVIETQAGDVSAYIPT 383 Query: 186 NVISITDGQIFLETELFYKGIRPAINVGLSVSRVGSAAQTKAMKQVAGRMKLELAQYREV 365 NVISITDGQIFLETELFYKGIRPAINVGLSVSRVGSAAQT+AMKQVAG MKLELAQYREV Sbjct: 384 NVISITDGQIFLETELFYKGIRPAINVGLSVSRVGSAAQTRAMKQVAGTMKLELAQYREV 443 Query: 366 AAFAQFGSDLDASTQQLLNRGVRLTELLKQGQYVPMAIEDQIVVIYAGVRGYLDKMDPSK 545 AAFAQFGSDLDA+TQQLL+RGVRLTELLKQGQY PMAIE+Q+ VIYAGVRGYLDK++PSK Sbjct: 444 AAFAQFGSDLDAATQQLLSRGVRLTELLKQGQYSPMAIEEQVAVIYAGVRGYLDKLEPSK 503 Query: 546 ITKFEQEYLKNVLVNHQDLLKDIRESGVISEANDAKMKKIVTDFVASFE 692 ITKFE +L +V+ HQ LL IR G ISE +DAK+K+IVT+F+A FE Sbjct: 504 ITKFENAFLSHVVSQHQALLGTIRADGKISEQSDAKLKEIVTNFLAGFE 552
>sp|P08428|ATPA_XENLA ATP synthase alpha chain, mitochondrial precursor Length = 545 Score = 380 bits (976), Expect = e-105 Identities = 195/229 (85%), Positives = 212/229 (92%) Frame = +3 Query: 6 MSLLLRRPPGREAYPGDVFYLHSRLLERAAKMSDVYGGGSLTALPVIETQAGDVSAYIPT 185 MSLLLRRPPGREAYPGDVFYLHSRLLERAAKM+D +GGGSLTALPVIETQAGDVSAYIPT Sbjct: 316 MSLLLRRPPGREAYPGDVFYLHSRLLERAAKMNDHFGGGSLTALPVIETQAGDVSAYIPT 375 Query: 186 NVISITDGQIFLETELFYKGIRPAINVGLSVSRVGSAAQTKAMKQVAGRMKLELAQYREV 365 NVISITDGQIFLETELFYKGIRPAINVGLSVSRVGSAAQT+AMKQVAG MKLELAQYREV Sbjct: 376 NVISITDGQIFLETELFYKGIRPAINVGLSVSRVGSAAQTRAMKQVAGTMKLELAQYREV 435 Query: 366 AAFAQFGSDLDASTQQLLNRGVRLTELLKQGQYVPMAIEDQIVVIYAGVRGYLDKMDPSK 545 AAFAQFGSDLDA+TQQLLNRGVRLTELLKQGQYVPMAIE+Q+ VIYAGVRG+LDKM+PSK Sbjct: 436 AAFAQFGSDLDAATQQLLNRGVRLTELLKQGQYVPMAIEEQVTVIYAGVRGHLDKMEPSK 495 Query: 546 ITKFEQEYLKNVLVNHQDLLKDIRESGVISEANDAKMKKIVTDFVASFE 692 ITKFE +L +V HQ+LL IR G ISE DAK+K+IV +F+++FE Sbjct: 496 ITKFESAFLAHVKSQHQELLATIRADGKISEQADAKLKEIVLNFLSTFE 544
>sp|P49375|ATPA_KLULA ATP synthase alpha chain, mitochondrial precursor Length = 548 Score = 325 bits (834), Expect = 6e-89 Identities = 168/228 (73%), Positives = 191/228 (83%) Frame = +3 Query: 6 MSLLLRRPPGREAYPGDVFYLHSRLLERAAKMSDVYGGGSLTALPVIETQAGDVSAYIPT 185 +SLLLRRPPGREAYPGDVFYLHSRLLERAAKMS+ GGGSLTALPVIETQ GDVSAYIPT Sbjct: 321 LSLLLRRPPGREAYPGDVFYLHSRLLERAAKMSEKNGGGSLTALPVIETQGGDVSAYIPT 380 Query: 186 NVISITDGQIFLETELFYKGIRPAINVGLSVSRVGSAAQTKAMKQVAGRMKLELAQYREV 365 NVISITDGQIFLE ELFYKGIRPAINVGLSVSRVGSAAQ KA+KQVAG +KL LAQYREV Sbjct: 381 NVISITDGQIFLEAELFYKGIRPAINVGLSVSRVGSAAQVKALKQVAGSLKLFLAQYREV 440 Query: 366 AAFAQFGSDLDASTQQLLNRGVRLTELLKQGQYVPMAIEDQIVVIYAGVRGYLDKMDPSK 545 AAFAQFGSDLDAST+Q L RG RLT+LLKQ QY P+A E+Q+ +IYAGV GYLD +D S+ Sbjct: 441 AAFAQFGSDLDASTKQTLARGERLTQLLKQNQYSPLAAEEQVPLIYAGVNGYLDNIDISR 500 Query: 546 ITKFEQEYLKNVLVNHQDLLKDIRESGVISEANDAKMKKIVTDFVASF 689 I +FE ++L + NH +++ IRE G +S+ A +K FVA+F Sbjct: 501 IAEFETKFLAYLKANHDEIVSAIREKGELSKELLATLKSATESFVATF 548
>sp|P24487|ATPA_SCHPO ATP synthase alpha chain, mitochondrial precursor Length = 536 Score = 322 bits (824), Expect = 9e-88 Identities = 159/228 (69%), Positives = 197/228 (86%) Frame = +3 Query: 6 MSLLLRRPPGREAYPGDVFYLHSRLLERAAKMSDVYGGGSLTALPVIETQAGDVSAYIPT 185 MSLLLRRPPGREAYPGDVFYLHSRLLERAAKMS +GGGSLTALPVIETQ GDVSAYIPT Sbjct: 309 MSLLLRRPPGREAYPGDVFYLHSRLLERAAKMSPKHGGGSLTALPVIETQGGDVSAYIPT 368 Query: 186 NVISITDGQIFLETELFYKGIRPAINVGLSVSRVGSAAQTKAMKQVAGRMKLELAQYREV 365 NVISITDGQIFLE+ELF+KGIRPAINVGLSVSRVGSAAQ KAMKQVAG++KL LAQYREV Sbjct: 369 NVISITDGQIFLESELFFKGIRPAINVGLSVSRVGSAAQVKAMKQVAGQIKLFLAQYREV 428 Query: 366 AAFAQFGSDLDASTQQLLNRGVRLTELLKQGQYVPMAIEDQIVVIYAGVRGYLDKMDPSK 545 A+FAQFGSDLDA T+ L+RG+RLTELLKQ QY P+A+E+Q+ +IY GV+GYLDK+ + Sbjct: 429 ASFAQFGSDLDAGTRATLDRGLRLTELLKQPQYSPLAVEEQVPLIYCGVKGYLDKIPVDR 488 Query: 546 ITKFEQEYLKNVLVNHQDLLKDIRESGVISEANDAKMKKIVTDFVASF 689 + +FE +++ + + ++++ IR+ GV+S+ + +K ++ +F++SF Sbjct: 489 VVEFEHKFIPYLRSSGAEIMEAIRKEGVLSKTTEDSLKAVIKEFLSSF 536
>sp|P37211|ATPA_NEUCR ATP synthase alpha chain, mitochondrial precursor Length = 551 Score = 320 bits (819), Expect = 3e-87 Identities = 161/230 (70%), Positives = 193/230 (83%) Frame = +3 Query: 6 MSLLLRRPPGREAYPGDVFYLHSRLLERAAKMSDVYGGGSLTALPVIETQAGDVSAYIPT 185 MSLLLRRPPGREAYPGDVFYLHSRLLERAAKM+ +GGGS+TALPVIETQ GDVSAYIPT Sbjct: 322 MSLLLRRPPGREAYPGDVFYLHSRLLERAAKMNKTHGGGSMTALPVIETQGGDVSAYIPT 381 Query: 186 NVISITDGQIFLETELFYKGIRPAINVGLSVSRVGSAAQTKAMKQVAGRMKLELAQYREV 365 NVISITDGQIFLE+ELFYKG+RPAINVGLSVSRVGSAAQ KAMKQVAG +KL LAQYREV Sbjct: 382 NVISITDGQIFLESELFYKGVRPAINVGLSVSRVGSAAQLKAMKQVAGSLKLFLAQYREV 441 Query: 366 AAFAQFGSDLDASTQQLLNRGVRLTELLKQGQYVPMAIEDQIVVIYAGVRGYLDKMDPSK 545 AAFAQFGSDLDA+T+Q LNRG RLTELLKQ QY PMA+ + + +I+AGV G+LD + +K Sbjct: 442 AAFAQFGSDLDAATKQTLNRGERLTELLKQKQYSPMAVNEMVPLIFAGVNGFLDSVPVAK 501 Query: 546 ITKFEQEYLKNVLVNHQDLLKDIRESGVISEANDAKMKKIVTDFVASFEG 695 I ++E ++L ++ N +++ I + G IS+ +AK++ ++ F SF G Sbjct: 502 ILQWEADFLAHLKTNEPEIMATIDKEGAISKDLEAKLRDVIQTFTKSFLG 551
>sp|P07251|ATPA_YEAST ATP synthase alpha chain, mitochondrial precursor Length = 545 Score = 320 bits (819), Expect = 3e-87 Identities = 166/228 (72%), Positives = 190/228 (83%) Frame = +3 Query: 6 MSLLLRRPPGREAYPGDVFYLHSRLLERAAKMSDVYGGGSLTALPVIETQAGDVSAYIPT 185 +SLLLRRPPGREAYPGDVFYLHSRLLERAAK+S+ G GSLTALPVIETQ GDVSAYIPT Sbjct: 318 LSLLLRRPPGREAYPGDVFYLHSRLLERAAKLSEKEGSGSLTALPVIETQGGDVSAYIPT 377 Query: 186 NVISITDGQIFLETELFYKGIRPAINVGLSVSRVGSAAQTKAMKQVAGRMKLELAQYREV 365 NVISITDGQIFLE ELFYKGIRPAINVGLSVSRVGSAAQ KA+KQVAG +KL LAQYREV Sbjct: 378 NVISITDGQIFLEAELFYKGIRPAINVGLSVSRVGSAAQVKALKQVAGSLKLFLAQYREV 437 Query: 366 AAFAQFGSDLDASTQQLLNRGVRLTELLKQGQYVPMAIEDQIVVIYAGVRGYLDKMDPSK 545 AAFAQFGSDLDAST+Q L RG RLT+LLKQ QY P+A E+Q+ +IYAGV G+LD ++ S+ Sbjct: 438 AAFAQFGSDLDASTKQTLVRGERLTQLLKQNQYSPLATEEQVPLIYAGVNGHLDGIELSR 497 Query: 546 ITKFEQEYLKNVLVNHQDLLKDIRESGVISEANDAKMKKIVTDFVASF 689 I +FE +L + NH +LL +IRE G +S+ A +K FVA+F Sbjct: 498 IGEFESSFLSYLKSNHNELLTEIREKGELSKELLASLKSATESFVATF 545
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 77,815,966 Number of Sequences: 369166 Number of extensions: 1536219 Number of successful extensions: 4275 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 4079 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 4187 length of database: 68,354,980 effective HSP length: 108 effective length of database: 48,403,600 effective search space used: 6728100400 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)