Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_016_L19
(237 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P28798|GRN_MOUSE Granulins precursor (Acrogranin) (Proep... 52 3e-07
sp|P28797|GRN_CAVPO Granulins precursor (Proepithelin) (PEP... 52 4e-07
sp|P80930|ENA1_HORSE Antimicrobial peptide eNAP-1 52 6e-07
sp|P23785|GRN_RAT Granulins precursor [Contains: Acrogranin... 51 7e-07
sp|P28799|GRN_HUMAN Granulins precursor (Proepithelin) (PEP... 49 5e-06
sp|P80059|PMD1_LOCMI Pars intercerebralis major peptide D1 ... 47 1e-05
sp|P81013|GRN1_CYPCA Granulin-1 45 5e-05
sp|P81015|GRN3_CYPCA Granulin-3 44 2e-04
sp|P81014|GRN2_CYPCA Granulin-2 42 6e-04
sp|P25777|ORYB_ORYSA Oryzain beta chain precursor 40 0.002
>sp|P28798|GRN_MOUSE Granulins precursor (Acrogranin) (Proepithelin) (PEPI) (PC
cell-derived growth factor) (PCDGF) [Contains: Granulin
1; Granulin 2; Granulin 3; Granulin 4; Granulin 5;
Granulin 6; Granulin 7]
Length = 589
Score = 52.4 bits (124), Expect = 3e-07
Identities = 25/58 (43%), Positives = 29/58 (50%), Gaps = 3/58 (5%)
Frame = +1
Query: 10 CPDGG-QCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPATTA*LVM--CLVGSY 174
CPD QC TCC + TG YGCCP +CC D CC T L+ CL +Y
Sbjct: 207 CPDAKTQCPDDSTCCELPTGKYGCCPMPNAICCSDHLHCCPQDTVCDLIQSKCLSKNY 264
Score = 48.1 bits (113), Expect = 6e-06
Identities = 21/55 (38%), Positives = 26/55 (47%)
Frame = +1
Query: 10 CPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPATTA*LVMCLVGSY 174
C D +C TCC + +G +GCCP VCC D + CC T CL Y
Sbjct: 364 CDDFTRCPTNNTCCKLNSGDWGCCPIPEAVCCSDNQHCCPQGFT-----CLAQGY 413
Score = 47.8 bits (112), Expect = 8e-06
Identities = 19/40 (47%), Positives = 24/40 (60%)
Frame = +1
Query: 7 NCPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCC 126
+CP+G TCC + TG +GCCPF+ VCC D CC
Sbjct: 287 SCPEG------YTCCRLNTGAWGCCPFAKAVCCEDHIHCC 320
Score = 47.8 bits (112), Expect = 8e-06
Identities = 19/39 (48%), Positives = 22/39 (56%)
Frame = +1
Query: 10 CPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCC 126
C +G C QTCC G + CCP+ GVCC D R CC
Sbjct: 517 CGEGHFCHDNQTCCKDSAGVWACCPYLKGVCCRDGRHCC 555
Score = 44.7 bits (104), Expect = 7e-05
Identities = 19/49 (38%), Positives = 23/49 (46%), Gaps = 1/49 (2%)
Frame = +1
Query: 10 CPDGG-QCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPATTA*LV 153
CP +C TCC+M G +GCCP CC D CC + LV
Sbjct: 125 CPGSQFECPDSATCCIMVDGSWGCCPMPQASCCEDRVHCCPHGASCDLV 173
Score = 40.8 bits (94), Expect = 0.001
Identities = 17/40 (42%), Positives = 20/40 (50%)
Frame = +1
Query: 7 NCPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCC 126
+C G C +C L +G CCPFS GV C D CC
Sbjct: 60 SCQTHGHCPAGYSCLLTVSGTSSCCPFSKGVSCGDGYHCC 99
Score = 39.3 bits (90), Expect = 0.003
Identities = 16/44 (36%), Positives = 18/44 (40%)
Frame = +1
Query: 10 CPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPATT 141
C C QTCC G + CC VCC D + CC T
Sbjct: 442 CDQHTSCPVGQTCCPSLKGSWACCQLPHAVCCEDRQHCCPAGYT 485
>sp|P28797|GRN_CAVPO Granulins precursor (Proepithelin) (PEPI) [Contains: Acrogranin;
Granulin-1; Granulin-2; Granulin-3; Granulin-4;
Granulin-5; Granulin-6; Granulin-7]
Length = 591
Score = 52.0 bits (123), Expect = 4e-07
Identities = 21/44 (47%), Positives = 24/44 (54%), Gaps = 1/44 (2%)
Frame = +1
Query: 10 CPDG-GQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPAT 138
CPD QC TCCL+ +G YGCCP +CC D CC T
Sbjct: 208 CPDSRSQCPDDTTCCLLASGEYGCCPMPNAICCSDHLHCCPQDT 251
Score = 48.9 bits (115), Expect = 4e-06
Identities = 20/39 (51%), Positives = 21/39 (53%)
Frame = +1
Query: 10 CPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCC 126
C D C QTCC G + CCPF GVCC D R CC
Sbjct: 518 CGDRHFCHDEQTCCRDSRGGWACCPFHQGVCCKDQRHCC 556
Score = 48.5 bits (114), Expect = 5e-06
Identities = 19/40 (47%), Positives = 24/40 (60%)
Frame = +1
Query: 7 NCPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCC 126
+CP+G QTCC + +G +GCCPF VCC D CC
Sbjct: 288 SCPEG------QTCCRLQSGKWGCCPFPKAVCCEDHVHCC 321
Score = 45.4 bits (106), Expect = 4e-05
Identities = 20/49 (40%), Positives = 23/49 (46%), Gaps = 1/49 (2%)
Frame = +1
Query: 10 CPDGG-QCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPATTA*LV 153
CP G +C TCC M G +GCCP CC D CC + LV
Sbjct: 112 CPGGEFECPDSSTCCHMLDGSWGCCPMPQASCCEDRVHCCPHGASCDLV 160
Score = 39.3 bits (90), Expect = 0.003
Identities = 16/44 (36%), Positives = 18/44 (40%)
Frame = +1
Query: 10 CPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPATT 141
C C QTCC G + CC VCC D + CC T
Sbjct: 441 CDQHASCPVRQTCCPKLGGGWACCQLPHAVCCEDGQHCCPAGYT 484
Score = 35.0 bits (79), Expect = 0.054
Identities = 16/40 (40%), Positives = 18/40 (45%)
Frame = +1
Query: 7 NCPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCC 126
NCP G +C L G CCPFS + C D CC
Sbjct: 52 NCPIG------HSCVLTAAGTAACCPFSQAMACGDGHHCC 85
Score = 33.1 bits (74), Expect = 0.21
Identities = 12/33 (36%), Positives = 17/33 (51%)
Frame = +1
Query: 7 NCPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCC 105
+C + C CC + +G +GCCP S G C
Sbjct: 377 SCDEVVSCRPGNICCRLASGEWGCCPSSEGYLC 409
>sp|P80930|ENA1_HORSE Antimicrobial peptide eNAP-1
Length = 46
Score = 51.6 bits (122), Expect = 6e-07
Identities = 20/39 (51%), Positives = 22/39 (56%)
Frame = +1
Query: 10 CPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCC 126
C +G C QTCC G CCP+S GVCC D R CC
Sbjct: 4 CGEGHFCHDXQTCCRASQGGXACCPYSQGVCCADQRHCC 42
>sp|P23785|GRN_RAT Granulins precursor [Contains: Acrogranin; Granulin-1 (Granulin G);
Granulin-2 (Granulin F); Granulin-3 (Granulin B)
(Epithelin-2); Granulin-4 (Granulin A) (Epithelin-1);
Granulin-5 (Granulin C); Granulin-6 (Granulin D);
Granulin-7 (Granulin E)]
Length = 588
Score = 51.2 bits (121), Expect = 7e-07
Identities = 24/58 (41%), Positives = 28/58 (48%), Gaps = 3/58 (5%)
Frame = +1
Query: 10 CPDGG-QCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPATTA*LVM--CLVGSY 174
CPD QC TCC + TG YGCCP +CC D CC T L+ C+ Y
Sbjct: 206 CPDAKTQCPDDSTCCELPTGKYGCCPMPNAICCSDHLHCCPQDTVCDLIQSKCISKDY 263
Score = 49.3 bits (116), Expect = 3e-06
Identities = 20/40 (50%), Positives = 24/40 (60%)
Frame = +1
Query: 7 NCPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCC 126
+CPDG TCC + TG +GCCPF+ VCC D CC
Sbjct: 286 SCPDG------YTCCRLNTGAWGCCPFTKAVCCEDHIHCC 319
Score = 47.4 bits (111), Expect = 1e-05
Identities = 17/39 (43%), Positives = 21/39 (53%)
Frame = +1
Query: 10 CPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCC 126
C D C TCC + +G +GCCP VCC D + CC
Sbjct: 363 CDDFSSCPSNNTCCRLSSGDWGCCPMPEAVCCLDHQHCC 401
Score = 44.7 bits (104), Expect = 7e-05
Identities = 19/49 (38%), Positives = 23/49 (46%), Gaps = 1/49 (2%)
Frame = +1
Query: 10 CPDGG-QCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPATTA*LV 153
CP +C TCC+M G +GCCP CC D CC + LV
Sbjct: 125 CPGSQFECPDSATCCIMIDGSWGCCPMPQASCCEDRVHCCPHGASCDLV 173
Score = 44.7 bits (104), Expect = 7e-05
Identities = 18/39 (46%), Positives = 21/39 (53%)
Frame = +1
Query: 10 CPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCC 126
C G C Q+CC G + CCP+ GVCC D R CC
Sbjct: 516 CGAGHFCHDNQSCCKDSQGGWACCPYVKGVCCRDGRHCC 554
Score = 41.6 bits (96), Expect = 6e-04
Identities = 18/42 (42%), Positives = 24/42 (57%)
Frame = +1
Query: 1 KNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCC 126
+++CPDG +C L +G CCPFS GV C D + CC
Sbjct: 64 RDHCPDG------YSCLLTVSGTSSCCPFSEGVSCDDGQHCC 99
Score = 39.3 bits (90), Expect = 0.003
Identities = 16/44 (36%), Positives = 18/44 (40%)
Frame = +1
Query: 10 CPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPATT 141
C C QTCC G + CC VCC D + CC T
Sbjct: 441 CDQHTSCPVGQTCCPSLKGSWACCQLPHAVCCEDRQHCCPAGYT 484
>sp|P28799|GRN_HUMAN Granulins precursor (Proepithelin) (PEPI) [Contains: Acrogranin;
Paragranulin; Granulin-1 (Granulin G); Granulin-2
(Granulin F); Granulin-3 (Granulin B); Granulin-4
(Granulin A); Granulin-5 (Granulin C); Granulin-6
(Granulin D); Granulin-7 (Granulin E)]
Length = 593
Score = 48.5 bits (114), Expect = 5e-06
Identities = 20/45 (44%), Positives = 25/45 (55%)
Frame = +1
Query: 7 NCPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPATT 141
+CPDG TCC + +G +GCCPF+ VCC D CC T
Sbjct: 289 SCPDG------YTCCRLQSGAWGCCPFTQAVCCEDHIHCCPAGFT 327
Score = 47.4 bits (111), Expect = 1e-05
Identities = 18/40 (45%), Positives = 21/40 (52%), Gaps = 1/40 (2%)
Frame = +1
Query: 10 CPDGG-QCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCC 126
CPD +C TCC+M G +GCCP CC D CC
Sbjct: 126 CPDSQFECPDFSTCCVMVDGSWGCCPMPQASCCEDRVHCC 165
Score = 47.4 bits (111), Expect = 1e-05
Identities = 20/51 (39%), Positives = 25/51 (49%)
Frame = +1
Query: 1 KNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPATTA*LV 153
++ CPDG TCC + +G YGCCP CC D CC T L+
Sbjct: 212 RSRCPDG------STCCELPSGKYGCCPMPNATCCSDHLHCCPQDTVCDLI 256
Score = 47.4 bits (111), Expect = 1e-05
Identities = 17/44 (38%), Positives = 22/44 (50%)
Frame = +1
Query: 10 CPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPATT 141
C + C TCC + +G +GCCP VCC D + CC T
Sbjct: 366 CDNVSSCPSSDTCCQLTSGEWGCCPIPEAVCCSDHQHCCPQGYT 409
Score = 46.2 bits (108), Expect = 2e-05
Identities = 18/39 (46%), Positives = 21/39 (53%)
Frame = +1
Query: 10 CPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCC 126
C +G C QTCC + CCP+ GVCC D R CC
Sbjct: 521 CGEGHFCHDNQTCCRDNRQGWACCPYRQGVCCADRRHCC 559
Score = 38.9 bits (89), Expect = 0.004
Identities = 16/44 (36%), Positives = 18/44 (40%)
Frame = +1
Query: 10 CPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPATT 141
C C QTCC G + CC VCC D + CC T
Sbjct: 444 CDQHTSCPVGQTCCPSLGGSWACCQLPHAVCCEDRQHCCPAGYT 487
Score = 33.9 bits (76), Expect = 0.12
Identities = 13/39 (33%), Positives = 16/39 (41%)
Frame = +1
Query: 10 CPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCC 126
C C+ +C +G CCPF V C D CC
Sbjct: 61 CQVDAHCSAGHSCIFTVSGTSSCCPFPEAVACGDGHHCC 99
>sp|P80059|PMD1_LOCMI Pars intercerebralis major peptide D1 (PMP-D1)
Length = 54
Score = 47.0 bits (110), Expect = 1e-05
Identities = 18/37 (48%), Positives = 20/37 (54%)
Frame = +1
Query: 28 CAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPAT 138
C G +TCC G GCCP+ GVCC D CC T
Sbjct: 7 CPGTETCCTTPQGEEGCCPYKEGVCCLDGIHCCPSGT 43
>sp|P81013|GRN1_CYPCA Granulin-1
Length = 57
Score = 45.1 bits (105), Expect = 5e-05
Identities = 20/39 (51%), Positives = 22/39 (56%)
Frame = +1
Query: 10 CPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCC 126
CPDG TCCL G + CCPFS+G CC D CC
Sbjct: 10 CPDG------TTCCLSPYGVWYCCPFSMGQCCRDGIHCC 42
>sp|P81015|GRN3_CYPCA Granulin-3
Length = 57
Score = 43.5 bits (101), Expect = 2e-04
Identities = 18/39 (46%), Positives = 20/39 (51%)
Frame = +1
Query: 10 CPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCC 126
C G C TCC G + CCPF +G CC D R CC
Sbjct: 4 CDAGITCPSGTTCCRSPFGVWYCCPFLMGQCCRDGRHCC 42
>sp|P81014|GRN2_CYPCA Granulin-2
Length = 57
Score = 41.6 bits (96), Expect = 6e-04
Identities = 16/33 (48%), Positives = 18/33 (54%)
Frame = +1
Query: 28 CAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCC 126
C TCC G + CCPF +G CC D R CC
Sbjct: 10 CPSRTTCCRSPFGVWYCCPFLMGQCCRDGRHCC 42
>sp|P25777|ORYB_ORYSA Oryzain beta chain precursor
Length = 471
Score = 40.0 bits (92), Expect = 0.002
Identities = 17/45 (37%), Positives = 22/45 (48%), Gaps = 3/45 (6%)
Frame = +1
Query: 7 NCPDGGQCA---GLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAP 132
+CP G C G + CL++ GCCP CC D +CC P
Sbjct: 390 SCPAGSTCCCAFGFRNLCLVW----GCCPVEGATCCKDHASCCPP 430
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 29,923,532
Number of Sequences: 369166
Number of extensions: 568292
Number of successful extensions: 1520
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 1402
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 1505
length of database: 68,354,980
effective HSP length: 49
effective length of database: 59,302,965
effective search space used: 1719785985
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)