Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_016_I22
(799 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q8BP47|SYNC_MOUSE Asparaginyl-tRNA synthetase, cytoplasm... 326 5e-89
sp|O43776|SYNC_HUMAN Asparaginyl-tRNA synthetase, cytoplasm... 324 1e-88
sp|P38707|SYNC_YEAST Asparaginyl-tRNA synthetase, cytoplasm... 303 3e-82
sp|Q6BU46|SYNC_DEBHA Asparaginyl-tRNA synthetase, cytoplasm... 285 1e-76
sp|Q19722|SYNC_CAEEL Asparaginyl-tRNA synthetase, cytoplasm... 280 3e-75
sp|O94567|SYNC_SCHPO Probable asparaginyl-tRNA synthetase, ... 268 2e-71
sp|P10723|SYNC_BRUMA Asparaginyl-tRNA synthetase, cytoplasm... 267 2e-71
sp|O57980|SYN_PYRHO Asparaginyl-tRNA synthetase (Asparagine... 176 5e-44
sp|Q8U4D3|SYN_PYRFU Asparaginyl-tRNA synthetase (Asparagine... 174 3e-43
sp|Q9V251|SYN_PYRAB Asparaginyl-tRNA synthetase (Asparagine... 174 3e-43
>sp|Q8BP47|SYNC_MOUSE Asparaginyl-tRNA synthetase, cytoplasmic (Asparagine--tRNA ligase)
(AsnRS)
Length = 547
Score = 326 bits (835), Expect = 5e-89
Identities = 146/236 (61%), Positives = 189/236 (80%), Gaps = 1/236 (0%)
Frame = +2
Query: 5 ECFSITRSYRAEKSRTRRHLSEYNHVEVESGFITFEDLLQQIEDMLVDVSELALEIGGKT 184
+ F I +SYRAE+SRTRRHL+E+ HVE E F+TFEDLL ++ED++ DV + L+ +
Sbjct: 312 DVFCIAQSYRAEQSRTRRHLAEFTHVEAECPFLTFEDLLNRLEDLVCDVVDRVLKSPVAS 371
Query: 185 LL-EINPDYKPLKKPFMRIEYKDAITFLREHGIEKPEGGSYEFGDDIPEAAERRMTDIIK 361
++ E+NP++KP K+PF R+ Y DAI +L+EH ++K +G YEFGDDIPEA ER MTD I
Sbjct: 372 IVYELNPNFKPPKRPFRRMNYSDAIEWLKEHDVKKEDGTFYEFGDDIPEAPERLMTDTIN 431
Query: 362 EPIMLTRFPVELKSFYMSKCKDDPRVTESVDVLIPGVGEIVGGSMRIWHLDELLAGYARE 541
EPI+L RFPVE+KSFYM +C +DPR+TESVDVL+P VGEIVGGSMR W +E+L GY RE
Sbjct: 432 EPILLCRFPVEIKSFYMQRCPEDPRLTESVDVLMPNVGEIVGGSMRSWDSEEILEGYKRE 491
Query: 542 NLDPEPYYWYTDMRRFGSCPHGGYGLGFERFLTWMMNKEHIRDVCLFPRYTGRCGP 709
+DP PYYWYTD R++G+CPHGGYGLG ERFL+W++N+ HIRDVCL+PR+ RC P
Sbjct: 492 GIDPAPYYWYTDQRKYGTCPHGGYGLGLERFLSWILNRYHIRDVCLYPRFLQRCRP 547
>sp|O43776|SYNC_HUMAN Asparaginyl-tRNA synthetase, cytoplasmic (Asparagine--tRNA ligase)
(AsnRS)
Length = 548
Score = 324 bits (831), Expect = 1e-88
Identities = 146/236 (61%), Positives = 189/236 (80%), Gaps = 1/236 (0%)
Frame = +2
Query: 5 ECFSITRSYRAEKSRTRRHLSEYNHVEVESGFITFEDLLQQIEDMLVDVSELALEI-GGK 181
+ F I +SYRAE+SRTRRHL+EY HVE E F+TF+DLL ++ED++ DV + L+ G
Sbjct: 313 DVFCIAQSYRAEQSRTRRHLAEYTHVEAECPFLTFDDLLNRLEDLVCDVVDRILKSPAGS 372
Query: 182 TLLEINPDYKPLKKPFMRIEYKDAITFLREHGIEKPEGGSYEFGDDIPEAAERRMTDIIK 361
+ E+NP+++P K+PF R+ Y DAI +L+EH ++K +G YEFG+DIPEA ER MTD I
Sbjct: 373 IVHELNPNFQPPKRPFKRMNYSDAIVWLKEHDVKKEDGTFYEFGEDIPEAPERLMTDTIN 432
Query: 362 EPIMLTRFPVELKSFYMSKCKDDPRVTESVDVLIPGVGEIVGGSMRIWHLDELLAGYARE 541
EPI+L RFPVE+KSFYM +C +D R+TESVDVL+P VGEIVGGSMRI+ +E+LAGY RE
Sbjct: 433 EPILLCRFPVEIKSFYMQRCPEDSRLTESVDVLMPNVGEIVGGSMRIFDSEEILAGYKRE 492
Query: 542 NLDPEPYYWYTDMRRFGSCPHGGYGLGFERFLTWMMNKEHIRDVCLFPRYTGRCGP 709
+DP PYYWYTD R++G+CPHGGYGLG ERFLTW++N+ HIRDVCL+PR+ RC P
Sbjct: 493 GIDPTPYYWYTDQRKYGTCPHGGYGLGLERFLTWILNRYHIRDVCLYPRFVQRCTP 548
>sp|P38707|SYNC_YEAST Asparaginyl-tRNA synthetase, cytoplasmic (Asparagine--tRNA ligase)
(AsnRS)
Length = 554
Score = 303 bits (777), Expect = 3e-82
Identities = 139/237 (58%), Positives = 181/237 (76%), Gaps = 2/237 (0%)
Frame = +2
Query: 5 ECFSITRSYRAEKSRTRRHLSEYNHVEVESGFITFEDLLQQIEDMLVDVSELALE--IGG 178
+ ++I S+RAEKS TRRHLSEY H+E E F+TF+DLLQ IE ++V + LE I G
Sbjct: 318 DVYTIQESFRAEKSHTRRHLSEYTHIEAELAFLTFDDLLQHIETLIVKSVQYVLEDPIAG 377
Query: 179 KTLLEINPDYKPLKKPFMRIEYKDAITFLREHGIEKPEGGSYEFGDDIPEAAERRMTDII 358
+ ++NP++K K PFMR++YKDAIT+L EH I+ EG ++FGDDI EAAER+MTD I
Sbjct: 378 PLVKQLNPNFKAPKAPFMRLQYKDAITWLNEHDIKNEEGEDFKFGDDIAEAAERKMTDTI 437
Query: 359 KEPIMLTRFPVELKSFYMSKCKDDPRVTESVDVLIPGVGEIVGGSMRIWHLDELLAGYAR 538
PI LTRFPVE+KSFYM +C DDPRVTESVDVL+P VGEI GGSMRI +DEL+AG+ R
Sbjct: 438 GVPIFLTRFPVEIKSFYMKRCSDDPRVTESVDVLMPNVGEITGGSMRIDDMDELMAGFKR 497
Query: 539 ENLDPEPYYWYTDMRRFGSCPHGGYGLGFERFLTWMMNKEHIRDVCLFPRYTGRCGP 709
E +D + YYW+ D R++G+CPHGGYG+G ER L W+ ++ +RD L+PR++GRC P
Sbjct: 498 EGIDTDAYYWFIDQRKYGTCPHGGYGIGTERILAWLCDRFTVRDCSLYPRFSGRCKP 554
>sp|Q6BU46|SYNC_DEBHA Asparaginyl-tRNA synthetase, cytoplasmic (Asparagine--tRNA ligase)
(AsnRS)
Length = 552
Score = 285 bits (729), Expect = 1e-76
Identities = 133/237 (56%), Positives = 173/237 (72%), Gaps = 2/237 (0%)
Frame = +2
Query: 5 ECFSITRSYRAEKSRTRRHLSEYNHVEVESGFITFEDLLQQIEDMLVDVSELALE--IGG 178
+ F + S+RAEKS TRRHLSEY H+E E GFI F+DLL +E ++ V + +E + G
Sbjct: 316 DVFCVQESFRAEKSHTRRHLSEYTHIESELGFIEFDDLLTHLERLITYVVKYVVEDPVAG 375
Query: 179 KTLLEINPDYKPLKKPFMRIEYKDAITFLREHGIEKPEGGSYEFGDDIPEAAERRMTDII 358
+ ++NP++ P + PF R+EY A+ +L EHGI +G ++FGDDI EAAER+MTD I
Sbjct: 376 PLIKQLNPNFVPPQMPFKRMEYIHALDWLNEHGIPNEDGEKFKFGDDIAEAAERKMTDTI 435
Query: 359 KEPIMLTRFPVELKSFYMSKCKDDPRVTESVDVLIPGVGEIVGGSMRIWHLDELLAGYAR 538
PI+L RFPVE+KSFYM KC DDPRVTESVDVL+P VGEI GGSMR + DEL+A R
Sbjct: 436 GVPILLIRFPVEIKSFYMQKCADDPRVTESVDVLMPTVGEITGGSMRTYDNDELVAAIKR 495
Query: 539 ENLDPEPYYWYTDMRRFGSCPHGGYGLGFERFLTWMMNKEHIRDVCLFPRYTGRCGP 709
E LD + YYW+TD R++G+CPHGGYGLG ER L W+ ++ +RD L+PR+TGRC P
Sbjct: 496 EGLDLDSYYWFTDQRKYGTCPHGGYGLGTERILAWLCDRFTVRDCSLYPRFTGRCKP 552
>sp|Q19722|SYNC_CAEEL Asparaginyl-tRNA synthetase, cytoplasmic (Asparagine--tRNA ligase)
(AsnRS)
Length = 545
Score = 280 bits (716), Expect = 3e-75
Identities = 132/237 (55%), Positives = 174/237 (73%), Gaps = 2/237 (0%)
Frame = +2
Query: 5 ECFSITRSYRAEKSRTRRHLSEYNHVEVESGFITFEDLLQQIEDMLVD-VSELALEIGGK 181
+ + I++SYRAEKSRTRRHLSEY HVE E FITF+ L+ +IE ++ D V L + K
Sbjct: 309 DVYCISQSYRAEKSRTRRHLSEYQHVEAECAFITFDQLMDRIEALVCDTVDRLLADPVTK 368
Query: 182 TLLE-INPDYKPLKKPFMRIEYKDAITFLREHGIEKPEGGSYEFGDDIPEAAERRMTDII 358
+L+E +NP YK +PF R+ YK+AI +L+++ + G + +G+DI EAAERRMTD I
Sbjct: 369 SLIEFVNPGYKAPARPFKRMPYKEAIEWLQKNDVRNEMGEKFVYGEDIAEAAERRMTDTI 428
Query: 359 KEPIMLTRFPVELKSFYMSKCKDDPRVTESVDVLIPGVGEIVGGSMRIWHLDELLAGYAR 538
PI+L RFP +K+FYM +C DD +TESVD+L+PGVGEIVGGSMRIW D+LLA + +
Sbjct: 429 GVPILLNRFPHGIKAFYMPRCADDNELTESVDLLMPGVGEIVGGSMRIWKEDQLLAAFEK 488
Query: 539 ENLDPEPYYWYTDMRRFGSCPHGGYGLGFERFLTWMMNKEHIRDVCLFPRYTGRCGP 709
LD + YYWY D R++GS PHGGYGLG ERF+ W+ + HIRDVCL+PR+ GRC P
Sbjct: 489 GGLDSKNYYWYMDQRKYGSVPHGGYGLGLERFICWLTDTNHIRDVCLYPRFVGRCAP 545
>sp|O94567|SYNC_SCHPO Probable asparaginyl-tRNA synthetase, cytoplasmic (Asparagine--tRNA
ligase) (AsnRS)
Length = 568
Score = 268 bits (684), Expect = 2e-71
Identities = 126/235 (53%), Positives = 166/235 (70%), Gaps = 2/235 (0%)
Frame = +2
Query: 11 FSITRSYRAEKSRTRRHLSEYNHVEVESGFITFEDLLQQIEDMLVDVSELALE--IGGKT 184
++I S+RAEKS TRRHLSE+ HVE E F+ F + L+ IE+ + + L+ I
Sbjct: 334 YTIQESFRAEKSLTRRHLSEFTHVEFELPFVNFGEFLEIIEEFICQTIDRLLDDPIATPL 393
Query: 185 LLEINPDYKPLKKPFMRIEYKDAITFLREHGIEKPEGGSYEFGDDIPEAAERRMTDIIKE 364
+ ++NPD+ +PFMR+ Y+DAI +L EH I PEG ++FGDDI EAAER+MTD I
Sbjct: 394 IKQLNPDFVKPSRPFMRLSYEDAIKYLNEHNILTPEGEQHKFGDDIAEAAERKMTDQINR 453
Query: 365 PIMLTRFPVELKSFYMSKCKDDPRVTESVDVLIPGVGEIVGGSMRIWHLDELLAGYAREN 544
PI LT FP+E+KSFYM + D P +TESVD L+P VGEIVGGSMRI + ELLA Y RE
Sbjct: 454 PIFLTYFPLEIKSFYMKRVVDRPELTESVDCLMPNVGEIVGGSMRISDIQELLAAYKREG 513
Query: 545 LDPEPYYWYTDMRRFGSCPHGGYGLGFERFLTWMMNKEHIRDVCLFPRYTGRCGP 709
+DP PYYW+T+ R++G+ HGG GLG ERFL W+ ++ +R+ CLFPR+T RC P
Sbjct: 514 IDPAPYYWFTEQRKYGTTEHGGCGLGLERFLAWLCDRYTVRECCLFPRFTERCTP 568
>sp|P10723|SYNC_BRUMA Asparaginyl-tRNA synthetase, cytoplasmic (Asparagine--tRNA ligase)
(AsnRS) (Potentially protective 63 kDa antigen)
Length = 548
Score = 267 bits (683), Expect = 2e-71
Identities = 122/218 (55%), Positives = 161/218 (73%), Gaps = 2/218 (0%)
Frame = +2
Query: 62 LSEYNHVEVESGFITFEDLLQQIEDMLVDVSE--LALEIGGKTLLEINPDYKPLKKPFMR 235
L+EY HVE E FIT +DL+++IE+++ D + LA E K L INP ++P ++PF+R
Sbjct: 331 LAEYAHVEAECPFITLDDLMEKIEELVCDTVDRLLADEEAKKLLEHINPKFQPPERPFLR 390
Query: 236 IEYKDAITFLREHGIEKPEGGSYEFGDDIPEAAERRMTDIIKEPIMLTRFPVELKSFYMS 415
+EYKDAI +L+EH +E G ++ +G+DI EAAER MTD I +PI+L RFP E+K+FYM
Sbjct: 391 MEYKDAIKWLQEHNVENEFGNTFTYGEDIAEAAERFMTDTINKPILLNRFPSEIKAFYMQ 450
Query: 416 KCKDDPRVTESVDVLIPGVGEIVGGSMRIWHLDELLAGYARENLDPEPYYWYTDMRRFGS 595
+ D +TESVD+L+PGVGEIVGGSMRIW DEL + +DP+PYYWY D R +G+
Sbjct: 451 RDAQDNTLTESVDLLMPGVGEIVGGSMRIWKFDELSKAFKNVEIDPKPYYWYLDQRLYGT 510
Query: 596 CPHGGYGLGFERFLTWMMNKEHIRDVCLFPRYTGRCGP 709
CPHGGYGLG ERF+ W+ N HIRDVCL+PR+ GRC P
Sbjct: 511 CPHGGYGLGLERFICWLTNTNHIRDVCLYPRFVGRCVP 548
>sp|O57980|SYN_PYRHO Asparaginyl-tRNA synthetase (Asparagine--tRNA ligase) (AsnRS)
Length = 434
Score = 176 bits (447), Expect = 5e-44
Identities = 94/237 (39%), Positives = 141/237 (59%), Gaps = 4/237 (1%)
Frame = +2
Query: 11 FSITRSYRAEKSRTRRHLSEYNHVEVESGFITFEDLLQQIEDMLVDVSELALEIGGKTLL 190
+S+T S+RAEKSRTRRHL+E+ H+E+E+ ++ D+++ E+++ + + LE+ K +
Sbjct: 204 WSLTPSFRAEKSRTRRHLTEFWHLELEAAWMDLWDIMKVEEELVSYMVQRTLELRKKEIE 263
Query: 191 EINPDYKPLKK---PFMRIEYKDAITFLREHGIEKPEGGSYEFGDDIPEAAERRMTDIIK 361
D LK PF RI Y +AI L+ G+ + E+GDD+ ER +T+
Sbjct: 264 MFRDDLTTLKNTEPPFPRISYDEAIDILQSKGV------NVEWGDDLGADEERVLTEEFD 317
Query: 362 EPIMLTRFPVELKSFYMSKCKDDPRVTESVDVLIP-GVGEIVGGSMRIWHLDELLAGYAR 538
P + +P +K+FYM + +DPR + D+L P G GEI+GGS R D+LL
Sbjct: 318 RPFFVYGYPKHIKAFYMKEDPNDPRKVLASDMLAPEGYGEIIGGSQREDDYDKLLNRILE 377
Query: 539 ENLDPEPYYWYTDMRRFGSCPHGGYGLGFERFLTWMMNKEHIRDVCLFPRYTGRCGP 709
E +DP+ Y WY D+RR+GS PH G+GLG ER + W++ +HIR LFPR R P
Sbjct: 378 EGMDPKDYEWYLDLRRYGSVPHSGFGLGVERLVAWVLKLDHIRWAALFPRTPARLYP 434
>sp|Q8U4D3|SYN_PYRFU Asparaginyl-tRNA synthetase (Asparagine--tRNA ligase) (AsnRS)
Length = 434
Score = 174 bits (441), Expect = 3e-43
Identities = 92/237 (38%), Positives = 142/237 (59%), Gaps = 4/237 (1%)
Frame = +2
Query: 11 FSITRSYRAEKSRTRRHLSEYNHVEVESGFITFEDLLQQIEDMLVDVSELALEIGGKTLL 190
+S+T S+RAEKSRTRRHL+E+ H+E+E+ ++ D+++ E+++ + + LE+ K +
Sbjct: 204 WSLTPSFRAEKSRTRRHLTEFWHLELEAAWMDLWDIMKVEEELVSYMVQRTLELRKKEIE 263
Query: 191 EINPDYKPLKK---PFMRIEYKDAITFLREHGIEKPEGGSYEFGDDIPEAAERRMTDIIK 361
D LK PF RI Y +AI L+ GI + ++GDD+ ER +T+
Sbjct: 264 MFRDDLTTLKNTEPPFPRISYDEAIDILQSKGI------NVQWGDDLGADEERVLTEEFD 317
Query: 362 EPIMLTRFPVELKSFYMSKCKDDPRVTESVDVLIP-GVGEIVGGSMRIWHLDELLAGYAR 538
P + +P ++K+FYM + +DPR + D+L P G GEI+GGS R ++LL
Sbjct: 318 RPFFVYGYPKQIKAFYMKEDPNDPRKVLAADMLAPEGYGEIIGGSQREDDYEKLLNRILE 377
Query: 539 ENLDPEPYYWYTDMRRFGSCPHGGYGLGFERFLTWMMNKEHIRDVCLFPRYTGRCGP 709
E +DP+ Y WY D+R++GS PH G+GLG ER + W++ +HIR LFPR R P
Sbjct: 378 EGMDPKDYEWYLDLRKYGSVPHSGFGLGVERLVAWVLKLDHIRWASLFPRTPARLYP 434
>sp|Q9V251|SYN_PYRAB Asparaginyl-tRNA synthetase (Asparagine--tRNA ligase) (AsnRS)
Length = 434
Score = 174 bits (440), Expect = 3e-43
Identities = 92/237 (38%), Positives = 141/237 (59%), Gaps = 4/237 (1%)
Frame = +2
Query: 11 FSITRSYRAEKSRTRRHLSEYNHVEVESGFITFEDLLQQIEDMLVDVSELALEIGGKTLL 190
+S+T S+RAEKSRTRRHL+E+ H+E+E+ ++ D+++ E+++ + + LE+ K +
Sbjct: 204 WSLTPSFRAEKSRTRRHLTEFWHLELEAAWMDLWDIMKVEEELVSYMVQRTLELRKKEIE 263
Query: 191 EINPDYKPLKK---PFMRIEYKDAITFLREHGIEKPEGGSYEFGDDIPEAAERRMTDIIK 361
D LK PF RI Y +AI L+ G++ E+GDD+ ER +T
Sbjct: 264 MFRDDLTTLKNTEPPFPRISYDEAIEILQSKGVK------IEWGDDMGADEERVLTQEFD 317
Query: 362 EPIMLTRFPVELKSFYMSKCKDDPRVTESVDVLIP-GVGEIVGGSMRIWHLDELLAGYAR 538
P + +P +K+FYM + +DPR + D+L P G GEI+GGS R + D+L+
Sbjct: 318 RPFFVYGYPKHIKAFYMKEDPNDPRKVLAADMLAPEGYGEIIGGSEREDNYDKLVQRIKE 377
Query: 539 ENLDPEPYYWYTDMRRFGSCPHGGYGLGFERFLTWMMNKEHIRDVCLFPRYTGRCGP 709
E +DP+ Y WY D+R++GS PH G+GLG ER + W++ +HIR LFPR R P
Sbjct: 378 EGMDPKDYEWYLDLRKYGSVPHSGFGLGVERLVAWVLKLDHIRWATLFPRTPARIYP 434
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 101,526,214
Number of Sequences: 369166
Number of extensions: 2331472
Number of successful extensions: 7890
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 7204
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 7568
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 7522142940
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)