Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_016_I05
(599 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q24746|NEUR_DROVI Neuralized protein 64 2e-10
sp|P29503|NEUR_DROME Neuralized protein 64 2e-10
sp|O76050|NEUL1_HUMAN Neuralized-like protein 1 (h-neuraliz... 55 1e-07
sp|Q923S6|NEURL_MOUSE Neuralized-like protein 1 (m-neuraliz... 55 1e-07
sp|Q6UWE0|LRSM1_HUMAN Ubiquitin ligase protein LRSAM1 (Leuc... 45 1e-04
sp|Q80ZI6|LRSM1_MOUSE Ubiquitin ligase protein LRSAM1 (Leuc... 44 3e-04
sp|O10296|IAP1_NPVOP Apoptosis inhibitor 1 (IAP-1) 44 3e-04
sp|P41435|IAP1_NPVAC Apoptosis inhibitor 1 (IAP-1) 44 4e-04
sp|Q09463|RNF5_CAEEL RING finger protein 5 43 7e-04
sp|Q99675|CGRF1_HUMAN Cell growth regulator with RING finge... 42 0.001
>sp|Q24746|NEUR_DROVI Neuralized protein
Length = 747
Score = 64.3 bits (155), Expect = 2e-10
Identities = 25/65 (38%), Positives = 42/65 (64%)
Frame = +1
Query: 265 RNNSDALNSCVICMNCTSDSMMYRCGHLCLCYPCSIQFRLNSNGGAMSCPVCRADVQEII 444
+ ++D+ C IC DS++Y CGH+C+CY C+I+ GG CP+CRA ++++I
Sbjct: 685 QQSTDSSAECTICYENPIDSVLYMCGHMCMCYDCAIEQWRGVGGG--QCPLCRAVIRDVI 742
Query: 445 RVFTS 459
R +T+
Sbjct: 743 RTYTT 747
>sp|P29503|NEUR_DROME Neuralized protein
Length = 754
Score = 64.3 bits (155), Expect = 2e-10
Identities = 25/65 (38%), Positives = 42/65 (64%)
Frame = +1
Query: 265 RNNSDALNSCVICMNCTSDSMMYRCGHLCLCYPCSIQFRLNSNGGAMSCPVCRADVQEII 444
+ ++D+ C IC DS++Y CGH+C+CY C+I+ GG CP+CRA ++++I
Sbjct: 692 QQSTDSSAECTICYENPIDSVLYMCGHMCMCYDCAIEQWRGVGGG--QCPLCRAVIRDVI 749
Query: 445 RVFTS 459
R +T+
Sbjct: 750 RTYTT 754
>sp|O76050|NEUL1_HUMAN Neuralized-like protein 1 (h-neuralized 1) (h-neu) (RING finger
protein 67)
Length = 574
Score = 55.5 bits (132), Expect = 1e-07
Identities = 20/58 (34%), Positives = 35/58 (60%)
Frame = +1
Query: 286 NSCVICMNCTSDSMMYRCGHLCLCYPCSIQFRLNSNGGAMSCPVCRADVQEIIRVFTS 459
+ C IC D+++Y CGH+CLCY C ++ + + CP+CR +++II+ + S
Sbjct: 519 DECTICYEHAVDTVIYTCGHMCLCYACGLRLKKALHA---CCPICRRPIKDIIKTYRS 573
>sp|Q923S6|NEURL_MOUSE Neuralized-like protein 1 (m-neuralized 1) (m-neu1)
Length = 574
Score = 55.5 bits (132), Expect = 1e-07
Identities = 20/58 (34%), Positives = 35/58 (60%)
Frame = +1
Query: 286 NSCVICMNCTSDSMMYRCGHLCLCYPCSIQFRLNSNGGAMSCPVCRADVQEIIRVFTS 459
+ C IC D+++Y CGH+CLCY C ++ + + CP+CR +++II+ + S
Sbjct: 519 DECTICYEHAVDTVIYTCGHMCLCYSCGLRLKKALHA---CCPICRRPIKDIIKTYRS 573
>sp|Q6UWE0|LRSM1_HUMAN Ubiquitin ligase protein LRSAM1 (Leucine-rich repeat and sterile
alpha motif containing 1) (Tsg101-associated ligase)
(hTAL)
Length = 723
Score = 45.4 bits (106), Expect = 1e-04
Identities = 17/58 (29%), Positives = 30/58 (51%)
Frame = +1
Query: 286 NSCVICMNCTSDSMMYRCGHLCLCYPCSIQFRLNSNGGAMSCPVCRADVQEIIRVFTS 459
+ CV+C+ + + CGH+C C C R +CP+CR D+ + +R++ S
Sbjct: 673 SECVVCLEREAQMIFLNCGHVCCCQQCCQPLR--------TCPLCRQDIAQRLRIYHS 722
>sp|Q80ZI6|LRSM1_MOUSE Ubiquitin ligase protein LRSAM1 (Leucine-rich repeat and sterile
alpha motif containing 1) (Tsg101-associated ligase)
Length = 727
Score = 43.9 bits (102), Expect = 3e-04
Identities = 16/58 (27%), Positives = 30/58 (51%)
Frame = +1
Query: 286 NSCVICMNCTSDSMMYRCGHLCLCYPCSIQFRLNSNGGAMSCPVCRADVQEIIRVFTS 459
+ CV+C+ + + CGH+C C C R +CP+CR ++ + +R++ S
Sbjct: 677 SECVVCLEREAQMVFLTCGHVCCCQQCCQPLR--------TCPLCRQEISQRLRIYHS 726
>sp|O10296|IAP1_NPVOP Apoptosis inhibitor 1 (IAP-1)
Length = 275
Score = 43.9 bits (102), Expect = 3e-04
Identities = 21/62 (33%), Positives = 33/62 (53%)
Frame = +1
Query: 274 SDALNSCVICMNCTSDSMMYRCGHLCLCYPCSIQFRLNSNGGAMSCPVCRADVQEIIRVF 453
S+AL C +C+ D+++ C H C+C C F L+ CP CR DV + I++F
Sbjct: 222 SEALE-CKVCLERQRDAVLLPCRHFCVCMQC--YFALDG-----KCPTCRQDVADFIKIF 273
Query: 454 TS 459
+
Sbjct: 274 VT 275
>sp|P41435|IAP1_NPVAC Apoptosis inhibitor 1 (IAP-1)
Length = 286
Score = 43.5 bits (101), Expect = 4e-04
Identities = 19/68 (27%), Positives = 32/68 (47%), Gaps = 3/68 (4%)
Frame = +1
Query: 259 DIRNNSDALNS---CVICMNCTSDSMMYRCGHLCLCYPCSIQFRLNSNGGAMSCPVCRAD 429
++ N+D + C +C+ D+++ C H C+C C G CP CR D
Sbjct: 224 NLNENADDIEEKYECKVCLERQRDAVLMPCRHFCVCVQCYF-------GLDQKCPTCRQD 276
Query: 430 VQEIIRVF 453
V + I++F
Sbjct: 277 VTDFIKIF 284
>sp|Q09463|RNF5_CAEEL RING finger protein 5
Length = 235
Score = 42.7 bits (99), Expect = 7e-04
Identities = 23/63 (36%), Positives = 35/63 (55%)
Frame = +1
Query: 244 SSSTKDIRNNSDALNSCVICMNCTSDSMMYRCGHLCLCYPCSIQFRLNSNGGAMSCPVCR 423
SSS KD A C IC++ D+++ CGHL C+PC Q+ L++ CPVC+
Sbjct: 14 SSSNKD----ESARFECNICLDAAKDAVVSLCGHL-FCWPCLSQW-LDTRPNNQVCPVCK 67
Query: 424 ADV 432
+ +
Sbjct: 68 SAI 70
>sp|Q99675|CGRF1_HUMAN Cell growth regulator with RING finger domain 1 (Cell growth
regulatory gene 19 protein)
Length = 332
Score = 42.4 bits (98), Expect = 0.001
Identities = 31/121 (25%), Positives = 49/121 (40%)
Frame = +1
Query: 76 EFNRQRSMNISANIEHANMLHSMRNEISEMKSMIRIMLQSQIETHRFLRQEMAAVFSSST 255
+F+ + + +SAN N N SE K+ R +L+ S
Sbjct: 221 QFHDLKQLFMSAN----NNFTPSNNSSSEEKNTDRSLLEK---------------VGLSE 261
Query: 256 KDIRNNSDALNSCVICMNCTSDSMMYRCGHLCLCYPCSIQFRLNSNGGAMSCPVCRADVQ 435
++ + + CV+C N T + ++ C H CLC C F+ CP+CR VQ
Sbjct: 262 SEVEPSEENSKDCVVCQNGTVNWVLLPCRHTCLCDGCVKYFQ--------QCPMCRQFVQ 313
Query: 436 E 438
E
Sbjct: 314 E 314
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 61,803,743
Number of Sequences: 369166
Number of extensions: 1111482
Number of successful extensions: 3273
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 2973
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3160
length of database: 68,354,980
effective HSP length: 105
effective length of database: 48,957,805
effective search space used: 4602033670
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)