Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_016_G22
(469 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P59780|AP3S2_HUMAN Adapter-related protein complex 3 sig... 175 4e-44
sp|Q92572|AP3S1_HUMAN Adapter-related protein complex 3 sig... 169 4e-42
sp|Q09905|YAJ5_SCHPO Adaptin complex small chain homolog C3... 113 2e-25
sp|P47064|AP22_YEAST Probable adaptin complex small chain h... 98 8e-21
sp|P61967|AP1S1_MOUSE Adapter-related protein complex 1 sig... 82 6e-16
sp|P56377|AP1S2_HUMAN Adapter-related protein complex 1 sig... 80 2e-15
sp|Q9DB50|AP1S2_MOUSE Adapter-related protein complex 1 sig... 79 4e-15
sp|P62743|AP2S1_MOUSE Clathrin coat assembly protein AP17 (... 79 7e-15
sp|Q9Y587|AP4S1_HUMAN Adapter-related protein complex 4 sig... 78 9e-15
sp|Q96PC3|AP1S3_HUMAN Adapter-related protein complex 1 sig... 78 1e-14
>sp|P59780|AP3S2_HUMAN Adapter-related protein complex 3 sigma 2 subunit (Sigma-adaptin
3b) (AP-3 complex sigma-3B subunit) (Sigma-3B-adaptin)
sp|Q8BSZ2|AP3S2_MOUSE Adapter-related protein complex 3 sigma 2 subunit (Sigma-adaptin
3b) (AP-3 complex sigma-3B subunit) (Sigma-3B-adaptin)
sp|Q5RDP9|AP3S2_PONPY Adapter-related protein complex 3 sigma 2 subunit (Sigma-adaptin
3b) (AP-3 complex sigma-3B subunit) (Sigma-3B-adaptin)
Length = 193
Score = 175 bits (444), Expect = 4e-44
Identities = 85/120 (70%), Positives = 105/120 (87%)
Frame = +2
Query: 2 LVYRHYATLYFVFCVDSSESELGILDLIQVFVESLDKAFENVCELDLIFNIDKVHHILKE 181
L+YRHYATLYFVFCVDSSESELGILDLIQVFVE+LDK FENVCELDLIF++DKVH+IL+E
Sbjct: 63 LIYRHYATLYFVFCVDSSESELGILDLIQVFVETLDKCFENVCELDLIFHMDKVHYILQE 122
Query: 182 VVLGGLVLDTHMTEILSRFEEQNKLEREENGLSIKSGSAVSAVKSINIPQRIRDIKLTDL 361
VV+GG+VL+T+M EI+++ E QN+LE+ E GLS AVSAVK+IN+P+ R+I + DL
Sbjct: 123 VVMGGMVLETNMNEIVAQIEAQNRLEKSEGGLSAAPARAVSAVKNINLPEIPRNINIGDL 182
>sp|Q92572|AP3S1_HUMAN Adapter-related protein complex 3 sigma 1 subunit (Sigma-adaptin
3a) (AP-3 complex sigma-3A subunit) (Sigma-3A-adaptin)
(Clathrin-associated/assembly/adapter protein, small 3)
sp|Q9DCR2|AP3S1_MOUSE Adapter-related protein complex 3 sigma 1 subunit (Sigma-adaptin
3a) (AP-3 complex sigma-3A subunit) (Sigma-3A-adaptin)
Length = 193
Score = 169 bits (427), Expect = 4e-42
Identities = 81/120 (67%), Positives = 104/120 (86%)
Frame = +2
Query: 2 LVYRHYATLYFVFCVDSSESELGILDLIQVFVESLDKAFENVCELDLIFNIDKVHHILKE 181
L+YRHYATLYFVFCVDSSESELGILDLIQVFVE+LDK FENVCELDLIF++DKVH+IL E
Sbjct: 63 LIYRHYATLYFVFCVDSSESELGILDLIQVFVETLDKCFENVCELDLIFHVDKVHNILAE 122
Query: 182 VVLGGLVLDTHMTEILSRFEEQNKLEREENGLSIKSGSAVSAVKSINIPQRIRDIKLTDL 361
+V+GG+VL+T+M EI+++ + QNKLE+ E GL+ AVSAVK++N+P+ R+I + D+
Sbjct: 123 MVMGGMVLETNMNEIVTQIDAQNKLEKSEAGLAGAPARAVSAVKNMNLPEIPRNINIGDI 182
>sp|Q09905|YAJ5_SCHPO Adaptin complex small chain homolog C30D11.05
Length = 165
Score = 113 bits (283), Expect = 2e-25
Identities = 54/92 (58%), Positives = 68/92 (73%)
Frame = +2
Query: 2 LVYRHYATLYFVFCVDSSESELGILDLIQVFVESLDKAFENVCELDLIFNIDKVHHILKE 181
++YR YATLYFVF VD ESELGILDLIQVFVE+LD+ F NVCELDL+F ++H IL E
Sbjct: 61 IIYRQYATLYFVFVVDEGESELGILDLIQVFVEALDRCFNNVCELDLVFKFQEIHAILAE 120
Query: 182 VVLGGLVLDTHMTEILSRFEEQNKLEREENGL 277
VV GGLVL+T++ EI+ + Q + N +
Sbjct: 121 VVSGGLVLETNLNEIVLAAQNQMPKTKRSNAM 152
>sp|P47064|AP22_YEAST Probable adaptin complex small chain homolog
Length = 194
Score = 98.2 bits (243), Expect = 8e-21
Identities = 46/84 (54%), Positives = 63/84 (75%)
Frame = +2
Query: 2 LVYRHYATLYFVFCVDSSESELGILDLIQVFVESLDKAFENVCELDLIFNIDKVHHILKE 181
++Y++YATLYF F VD ESEL ILDLIQ FVESLD+ F V ELDLIFN + +L+E
Sbjct: 75 IIYKNYATLYFTFIVDDQESELAILDLIQTFVESLDRCFTEVNELDLIFNWQTLESVLEE 134
Query: 182 VVLGGLVLDTHMTEILSRFEEQNK 253
+V GG+V++T++ I++ +E NK
Sbjct: 135 IVQGGMVIETNVNRIVASVDELNK 158
>sp|P61967|AP1S1_MOUSE Adapter-related protein complex 1 sigma 1A subunit (Sigma-adaptin
1A) (Adaptor protein complex AP-1 sigma-1A subunit)
(Golgi adaptor HA1/AP1 adaptin sigma-1A subunit)
(Clathrin assembly protein complex 1 sigma-1A small
chain) (Clathrin coat assembly protein AP19) (HA1 19 kDa
subunit) (Sigma 1a subunit of AP-1 clathrin)
sp|P61966|AP1S1_HUMAN Adapter-related protein complex 1 sigma 1A subunit (Sigma-adaptin
1A) (Adaptor protein complex AP-1 sigma-1A subunit)
(Golgi adaptor HA1/AP1 adaptin sigma-1A subunit)
(Clathrin assembly protein complex 1 sigma-1A small
chain) (Clathrin coat assembly protein AP19) (HA1 19 kDa
subunit) (Sigma 1a subunit of AP-1 clathrin)
Length = 158
Score = 82.0 bits (201), Expect = 6e-16
Identities = 39/89 (43%), Positives = 59/89 (66%)
Frame = +2
Query: 2 LVYRHYATLYFVFCVDSSESELGILDLIQVFVESLDKAFENVCELDLIFNIDKVHHILKE 181
+VY+ YA+LYF ++ ++EL L+LI +VE LDK F +VCELD+IFN +K + IL E
Sbjct: 57 VVYKRYASLYFCCAIEGQDNELITLELIHRYVELLDKYFGSVCELDIIFNFEKAYFILDE 116
Query: 182 VVLGGLVLDTHMTEILSRFEEQNKLEREE 268
++GG V DT +L E+ + L+ E+
Sbjct: 117 FLMGGDVQDTSKKSVLKAIEQADLLQEED 145
>sp|P56377|AP1S2_HUMAN Adapter-related protein complex 1 sigma 1B subunit (Sigma-adaptin
1B) (Adaptor protein complex AP-1 sigma-1B subunit)
(Golgi adaptor HA1/AP1 adaptin sigma-1B subunit)
(Clathrin assembly protein complex 1 sigma-1B small
chain) (Sigma 1B subunit of AP-1 clathrin)
Length = 157
Score = 80.5 bits (197), Expect = 2e-15
Identities = 38/88 (43%), Positives = 58/88 (65%)
Frame = +2
Query: 2 LVYRHYATLYFVFCVDSSESELGILDLIQVFVESLDKAFENVCELDLIFNIDKVHHILKE 181
+VY+ YA+LYF ++ ++EL L++I +VE LDK F +VCELD+IFN +K + IL E
Sbjct: 56 IVYKRYASLYFCCAIEDQDNELITLEIIHRYVELLDKYFGSVCELDIIFNFEKAYFILDE 115
Query: 182 VVLGGLVLDTHMTEILSRFEEQNKLERE 265
+LGG V +T +L E+ + L+ E
Sbjct: 116 FLLGGEVQETSKKNVLKAIEQADLLQEE 143
>sp|Q9DB50|AP1S2_MOUSE Adapter-related protein complex 1 sigma 1B subunit (Sigma-adaptin
1B) (Adaptor protein complex AP-1 sigma-1B subunit)
(Golgi adaptor HA1/AP1 adaptin sigma-1B subunit)
(Clathrin assembly protein complex 1 sigma-1B small
chain) (Sigma 1B subunit of AP-1 clathrin)
Length = 160
Score = 79.3 bits (194), Expect = 4e-15
Identities = 37/88 (42%), Positives = 58/88 (65%)
Frame = +2
Query: 2 LVYRHYATLYFVFCVDSSESELGILDLIQVFVESLDKAFENVCELDLIFNIDKVHHILKE 181
+VY+ YA+LYF ++ ++EL L++I +VE LDK F +VCELD+IFN +K + IL E
Sbjct: 56 IVYKRYASLYFCCAIEDQDNELITLEIIHRYVELLDKYFGSVCELDIIFNFEKAYFILDE 115
Query: 182 VVLGGLVLDTHMTEILSRFEEQNKLERE 265
+LGG V +T +L E+ + L+ +
Sbjct: 116 FLLGGEVQETSKKNVLKAIEQADLLQED 143
>sp|P62743|AP2S1_MOUSE Clathrin coat assembly protein AP17 (Clathrin coat-associated
protein AP17) (Plasma membrane adaptor AP-2 17 kDa
protein) (Clathrin assembly protein 2 small chain)
sp|P62744|AP2S1_RAT Clathrin coat assembly protein AP17 (Clathrin coat-associated
protein AP17) (Plasma membrane adaptor AP-2 17 kDa
protein) (Clathrin assembly protein 2 small chain)
sp|Q5R940|AP2S1_PONPY Clathrin coat assembly protein AP17 (Clathrin coat-associated
protein AP17) (Plasma membrane adaptor AP-2 17 kDa
protein) (Clathrin assembly protein 2 small chain)
sp|P53680|AP2S1_HUMAN Clathrin coat assembly protein AP17 (Clathrin coat-associated
protein AP17) (Plasma membrane adaptor AP-2 17 kDa
protein) (HA2 17 kDa subunit) (Clathrin assembly protein
2 small chain)
Length = 142
Score = 78.6 bits (192), Expect = 7e-15
Identities = 37/86 (43%), Positives = 55/86 (63%)
Frame = +2
Query: 2 LVYRHYATLYFVFCVDSSESELGILDLIQVFVESLDKAFENVCELDLIFNIDKVHHILKE 181
++YR YA LYF CVD +++ L L+ I FVE L++ F NVCELDL+FN KV+ ++ E
Sbjct: 57 IIYRRYAGLYFCICVDVNDNNLAYLEAIHNFVEVLNEYFHNVCELDLVFNFYKVYTVVDE 116
Query: 182 VVLGGLVLDTHMTEILSRFEEQNKLE 259
+ L G + +T T++L + LE
Sbjct: 117 MFLAGEIRETSQTKVLKQLLMLQSLE 142
>sp|Q9Y587|AP4S1_HUMAN Adapter-related protein complex 4 sigma 1 subunit (Sigma subunit of
AP-4) (AP-4 adapter complex sigma subunit)
Length = 144
Score = 78.2 bits (191), Expect = 9e-15
Identities = 37/77 (48%), Positives = 54/77 (70%)
Frame = +2
Query: 2 LVYRHYATLYFVFCVDSSESELGILDLIQVFVESLDKAFENVCELDLIFNIDKVHHILKE 181
L+YR YA L+ V V+ +E+E+ I + I FVE LD+ F V ELD++FN+DKVH IL E
Sbjct: 57 LIYRQYAALFIVVGVNDTENEMAIYEFIHNFVEVLDEYFSRVSELDIMFNLDKVHIILDE 116
Query: 182 VVLGGLVLDTHMTEILS 232
+VL G +++T+ IL+
Sbjct: 117 MVLNGCIVETNRARILA 133
>sp|Q96PC3|AP1S3_HUMAN Adapter-related protein complex 1 sigma 1C subunit (Sigma-adaptin
1C) (Adaptor protein complex AP-1 sigma-1C subunit)
(Golgi adaptor HA1/AP1 adaptin sigma-1C subunit)
(Clathrin assembly protein complex 1 sigma-1C small
chain) (Sigma 1C subunit of AP-1 clathrin)
Length = 154
Score = 77.8 bits (190), Expect = 1e-14
Identities = 35/86 (40%), Positives = 57/86 (66%)
Frame = +2
Query: 2 LVYRHYATLYFVFCVDSSESELGILDLIQVFVESLDKAFENVCELDLIFNIDKVHHILKE 181
LVY+ YA+LYF +++ ++EL L+++ +VE LDK F NVCELD+IFN +K + IL E
Sbjct: 57 LVYKRYASLYFCCAIENQDNELLTLEIVHRYVELLDKYFGNVCELDIIFNFEKAYFILDE 116
Query: 182 VVLGGLVLDTHMTEILSRFEEQNKLE 259
++GG + +T + E+ + L+
Sbjct: 117 FIIGGEIQETSKKIAVKAIEDSDMLQ 142
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 44,689,234
Number of Sequences: 369166
Number of extensions: 767603
Number of successful extensions: 2500
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 2437
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 2495
length of database: 68,354,980
effective HSP length: 101
effective length of database: 49,696,745
effective search space used: 2683624230
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)