Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_016_G14
(376 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q16799|RTN1_HUMAN Reticulon-1 (Neuroendocrine-specific p... 48 6e-06
sp|Q5IS59|RTN1_PANTR Reticulon-1 48 6e-06
sp|Q64548|RTN1_RAT Reticulon-1 (Neuroendocrine-specific pro... 48 8e-06
sp|Q8K0T0|RTN1_MOUSE Reticulon-1 (Neuroendocrine-specific p... 48 8e-06
sp|Q9NQC3|RTN4_HUMAN Reticulon-4 (Neurite outgrowth inhibit... 46 3e-05
sp|O95197|RTN3_HUMAN Reticulon-3 (Neuroendocrine-specific p... 45 4e-05
sp|Q9ES97|RTN3_MOUSE Reticulon-3 45 5e-05
sp|Q99P72|RTN4_MOUSE Reticulon-4 (Neurite outgrowth inhibit... 45 7e-05
sp|Q9JK11|RTN4_RAT Reticulon-4 (Neurite outgrowth inhibitor... 44 1e-04
sp|O70622|RTN2_MOUSE Reticulon-2 (Neuroendocrine-specific p... 38 0.006
>sp|Q16799|RTN1_HUMAN Reticulon-1 (Neuroendocrine-specific protein)
Length = 776
Score = 48.1 bits (113), Expect = 6e-06
Identities = 27/76 (35%), Positives = 42/76 (55%)
Frame = +1
Query: 7 IFLLESYADVGKFLVGNVAMVYVGMYFNLIDLVTLAVLSLLTGPKVYNLYRRQIDDAVMK 186
+FL++ D KF V + YVG FN + L+ +AV+S+ T P VY ++ QID +
Sbjct: 693 LFLVQDLVDSLKFAVLMWLLTYVGALFNGLTLLLMAVVSMFTLPVVYVKHQAQIDQYLGL 752
Query: 187 AREHVGKAVAIAKEKL 234
R H+ VA + K+
Sbjct: 753 VRTHINAVVAKIQAKI 768
>sp|Q5IS59|RTN1_PANTR Reticulon-1
Length = 776
Score = 48.1 bits (113), Expect = 6e-06
Identities = 27/76 (35%), Positives = 42/76 (55%)
Frame = +1
Query: 7 IFLLESYADVGKFLVGNVAMVYVGMYFNLIDLVTLAVLSLLTGPKVYNLYRRQIDDAVMK 186
+FL++ D KF V + YVG FN + L+ +AV+S+ T P VY ++ QID +
Sbjct: 693 LFLVQDLVDSLKFAVLMWLLTYVGALFNGLTLLLMAVVSMFTLPVVYVKHQAQIDQYLGL 752
Query: 187 AREHVGKAVAIAKEKL 234
R H+ VA + K+
Sbjct: 753 VRTHINAVVAKIQAKI 768
>sp|Q64548|RTN1_RAT Reticulon-1 (Neuroendocrine-specific protein) (S-rex)
Length = 777
Score = 47.8 bits (112), Expect = 8e-06
Identities = 26/76 (34%), Positives = 42/76 (55%)
Frame = +1
Query: 7 IFLLESYADVGKFLVGNVAMVYVGMYFNLIDLVTLAVLSLLTGPKVYNLYRRQIDDAVMK 186
+FL++ D KF V + YVG FN + L+ +AV+S+ T P VY ++ Q+D +
Sbjct: 694 LFLVQDLVDSLKFAVLMWLLTYVGALFNGLTLLLMAVVSMFTLPVVYVKHQAQVDQYLGL 753
Query: 187 AREHVGKAVAIAKEKL 234
R H+ VA + K+
Sbjct: 754 VRTHINTVVAKIQAKI 769
>sp|Q8K0T0|RTN1_MOUSE Reticulon-1 (Neuroendocrine-specific protein)
Length = 780
Score = 47.8 bits (112), Expect = 8e-06
Identities = 26/76 (34%), Positives = 42/76 (55%)
Frame = +1
Query: 7 IFLLESYADVGKFLVGNVAMVYVGMYFNLIDLVTLAVLSLLTGPKVYNLYRRQIDDAVMK 186
+FL++ D KF V + YVG FN + L+ +AV+S+ T P VY ++ Q+D +
Sbjct: 697 LFLVQDLVDSLKFAVLMWLLTYVGALFNGLTLLLMAVVSMFTLPVVYVKHQAQVDQYLGL 756
Query: 187 AREHVGKAVAIAKEKL 234
R H+ VA + K+
Sbjct: 757 VRTHINTVVAKIQAKI 772
>sp|Q9NQC3|RTN4_HUMAN Reticulon-4 (Neurite outgrowth inhibitor) (Nogo protein) (Foocen)
(Neuroendocrine-specific protein) (NSP)
(Neuroendocrine-specific protein C homolog) (RTN-x)
(Reticulon-5)
Length = 1192
Score = 45.8 bits (107), Expect = 3e-05
Identities = 27/79 (34%), Positives = 44/79 (55%)
Frame = +1
Query: 7 IFLLESYADVGKFLVGNVAMVYVGMYFNLIDLVTLAVLSLLTGPKVYNLYRRQIDDAVMK 186
+FL++ D KF V YVG FN + L+ LA++SL + P +Y ++ QID +
Sbjct: 1109 LFLVDDLVDSLKFAVLMWVFTYVGALFNGLTLLILALISLFSVPVIYERHQAQIDHYLGL 1168
Query: 187 AREHVGKAVAIAKEKLATL 243
A ++V A+A + K+ L
Sbjct: 1169 ANKNVKDAMAKIQAKIPGL 1187
>sp|O95197|RTN3_HUMAN Reticulon-3 (Neuroendocrine-specific protein-like 2) (NSP-like
protein II) (NSPLII)
Length = 236
Score = 45.4 bits (106), Expect = 4e-05
Identities = 30/76 (39%), Positives = 38/76 (50%)
Frame = +1
Query: 7 IFLLESYADVGKFLVGNVAMVYVGMYFNLIDLVTLAVLSLLTGPKVYNLYRRQIDDAVMK 186
+FL+E D K V M YVG FN I L+ LA L + + P VY Y+ QID V
Sbjct: 152 LFLVEDLVDSLKLAVFMWLMTYVGAVFNGITLLILAELLIFSVPIVYEKYKTQIDHYVGI 211
Query: 187 AREHVGKAVAIAKEKL 234
AR+ V + KL
Sbjct: 212 ARDQTKSIVEKIQAKL 227
>sp|Q9ES97|RTN3_MOUSE Reticulon-3
Length = 237
Score = 45.1 bits (105), Expect = 5e-05
Identities = 30/76 (39%), Positives = 38/76 (50%)
Frame = +1
Query: 7 IFLLESYADVGKFLVGNVAMVYVGMYFNLIDLVTLAVLSLLTGPKVYNLYRRQIDDAVMK 186
+FL+E D K V M YVG FN I L+ LA L + + P VY Y+ QID V
Sbjct: 153 LFLVEDLVDSLKLAVFMWLMTYVGAVFNGITLLILAELLVFSVPIVYEKYKTQIDHYVGI 212
Query: 187 AREHVGKAVAIAKEKL 234
AR+ V + KL
Sbjct: 213 ARDQTKSIVEKIQAKL 228
>sp|Q99P72|RTN4_MOUSE Reticulon-4 (Neurite outgrowth inhibitor) (Nogo protein)
Length = 199
Score = 44.7 bits (104), Expect = 7e-05
Identities = 27/79 (34%), Positives = 43/79 (54%)
Frame = +1
Query: 7 IFLLESYADVGKFLVGNVAMVYVGMYFNLIDLVTLAVLSLLTGPKVYNLYRRQIDDAVMK 186
+FL++ D KF V YVG FN + L+ LA++SL + P +Y ++ QID +
Sbjct: 116 LFLVDDLVDSLKFAVLMWVFTYVGALFNGLTLLILALISLFSIPVIYERHQAQIDHYLGL 175
Query: 187 AREHVGKAVAIAKEKLATL 243
A + V A+A + K+ L
Sbjct: 176 ANKSVKDAMAKIQAKIPGL 194
>sp|Q9JK11|RTN4_RAT Reticulon-4 (Neurite outgrowth inhibitor) (Nogo protein) (Foocen)
(Glut4 vesicle 20 kDa protein)
Length = 1163
Score = 43.9 bits (102), Expect = 1e-04
Identities = 27/79 (34%), Positives = 43/79 (54%)
Frame = +1
Query: 7 IFLLESYADVGKFLVGNVAMVYVGMYFNLIDLVTLAVLSLLTGPKVYNLYRRQIDDAVMK 186
+FL++ D KF V YVG FN + L+ LA++SL + P +Y ++ QID +
Sbjct: 1080 LFLVDDLVDSLKFAVLMWVFTYVGALFNGLTLLILALISLFSIPVIYERHQVQIDHYLGL 1139
Query: 187 AREHVGKAVAIAKEKLATL 243
A + V A+A + K+ L
Sbjct: 1140 ANKSVKDAMAKIQAKIPGL 1158
>sp|O70622|RTN2_MOUSE Reticulon-2 (Neuroendocrine-specific protein-like 1) (NSP-like
protein 1) (NSPLI)
Length = 471
Score = 38.1 bits (87), Expect = 0.006
Identities = 28/93 (30%), Positives = 42/93 (45%), Gaps = 7/93 (7%)
Frame = +1
Query: 10 FLLESYADVGKFLVGNVAMVYVGMYFNLIDLVTLAVLSLLTGPKVYNLYRRQIDDAVMKA 189
FL+E D K + + +VG FN + LV L V++L T P +Y ++ QID V
Sbjct: 377 FLVEDLVDSLKLALLFYILTFVGAIFNGLTLVILGVVALFTVPLLYRQHQAQIDQYVGLV 436
Query: 190 REHVGKAVAIAKEKL-------ATLPVVGTKMK 267
+ A + K+ T V G+K K
Sbjct: 437 TNQLSHIKAKIRAKIPGTGTLAPTASVSGSKAK 469
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 41,966,647
Number of Sequences: 369166
Number of extensions: 811184
Number of successful extensions: 2749
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 2699
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 2747
length of database: 68,354,980
effective HSP length: 91
effective length of database: 51,544,095
effective search space used: 1700955135
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)