Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_016_G07
(702 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9W1V3|FBRL_DROME Fibrillarin 308 7e-84
sp|Q8I1F4|FBRL_DROER Fibrillarin 308 1e-83
sp|P35550|FBRL_MOUSE Fibrillarin (Nucleolar protein 1) 300 3e-81
sp|P22087|FBRL_HUMAN Fibrillarin (34 kDa nucleolar sclerode... 300 3e-81
sp|P22509|FBRL_RAT Fibrillarin (Nucleolar protein 1) 300 3e-81
sp|P22232|FBRL_XENLA Fibrillarin 293 4e-79
sp|Q22053|FBRL_CAEEL Fibrillarin 289 6e-78
sp|Q9FEF8|FBRL1_ARATH Fibrillarin-1 (SKP1 interacting partn... 276 5e-74
sp|Q94AH9|FBRL2_ARATH Fibrillarin-2 (Fibrillarin-like protein) 273 3e-73
sp|P35551|FBRL_SCHPO Fibrillarin 270 3e-72
>sp|Q9W1V3|FBRL_DROME Fibrillarin
Length = 344
Score = 308 bits (790), Expect = 7e-84
Identities = 144/215 (66%), Positives = 179/215 (83%)
Frame = +2
Query: 2 GKDETLLTKNFVPGVSVYGEKRIAIGTGDDKVEYRTWNPFRSKLAASVLNGIDSIHMPVG 181
GK++ L+T+NFVPG VYGEKRI++ T +K+EYR WNPFRSKLAA+VL G++ IHMP G
Sbjct: 126 GKEDALVTRNFVPGSEVYGEKRISVETNGEKIEYRVWNPFRSKLAAAVLGGVEQIHMPPG 185
Query: 182 SKVLYLGASTGTSVSHVSDIVGPTGVVYAVEFAERVGREMLNVAKKRTNIVPIIEDARHP 361
SKVLYLGA++GT+VSHVSD+VGP G+VYAVEF+ R GR+++NVAKKRTNI+PIIEDARHP
Sbjct: 186 SKVLYLGAASGTTVSHVSDVVGPEGLVYAVEFSHRSGRDLINVAKKRTNIIPIIEDARHP 245
Query: 362 HKYRMMINQVDTIFADVAQPDQSRIVAVNADFFLKPGGYAVISLKASCIDSTAEPESAFL 541
HKYRM++ VDTIFADVAQPDQ RIVA+NA FLK GG+ VIS+KASCIDSTA+PE+ F
Sbjct: 246 HKYRMLVGMVDTIFADVAQPDQGRIVALNAQHFLKNGGHFVISIKASCIDSTAQPEAVFA 305
Query: 542 SEKDVISKLKFKPDSWLSMEPFERDHKVLIAQYLP 646
+E + K KP L++EP+ERDH V++ Y P
Sbjct: 306 AEVKKMQADKLKPQEQLTLEPYERDHAVVVGVYRP 340
>sp|Q8I1F4|FBRL_DROER Fibrillarin
Length = 345
Score = 308 bits (788), Expect = 1e-83
Identities = 144/215 (66%), Positives = 178/215 (82%)
Frame = +2
Query: 2 GKDETLLTKNFVPGVSVYGEKRIAIGTGDDKVEYRTWNPFRSKLAASVLNGIDSIHMPVG 181
GK++ L+T+NFVPG VYGEKRI++ +K+EYR WNPFRSKLAA+VL G++ IHMP G
Sbjct: 127 GKEDALVTRNFVPGSEVYGEKRISVENNGEKIEYRVWNPFRSKLAAAVLGGVEQIHMPPG 186
Query: 182 SKVLYLGASTGTSVSHVSDIVGPTGVVYAVEFAERVGREMLNVAKKRTNIVPIIEDARHP 361
SKVLYLGA++GT+VSHVSD+VGP G+VYAVEF+ R GR+++NVAKKRTNI+PIIEDARHP
Sbjct: 187 SKVLYLGAASGTTVSHVSDVVGPEGLVYAVEFSHRSGRDLINVAKKRTNIIPIIEDARHP 246
Query: 362 HKYRMMINQVDTIFADVAQPDQSRIVAVNADFFLKPGGYAVISLKASCIDSTAEPESAFL 541
HKYRM++ VDTIFADVAQPDQ RIVA+NA FLK GG+ VIS+KASCIDSTA+PE+ F
Sbjct: 247 HKYRMLVGMVDTIFADVAQPDQGRIVALNAQHFLKNGGHFVISIKASCIDSTAQPEAVFA 306
Query: 542 SEKDVISKLKFKPDSWLSMEPFERDHKVLIAQYLP 646
SE + K KP L++EP+ERDH V++ Y P
Sbjct: 307 SEVKKMQADKLKPQEQLTLEPYERDHAVVVGVYRP 341
>sp|P35550|FBRL_MOUSE Fibrillarin (Nucleolar protein 1)
Length = 327
Score = 300 bits (767), Expect = 3e-81
Identities = 140/215 (65%), Positives = 177/215 (82%)
Frame = +2
Query: 2 GKDETLLTKNFVPGVSVYGEKRIAIGTGDDKVEYRTWNPFRSKLAASVLNGIDSIHMPVG 181
GK++ L+TKN VPG SVYGEKR++I GDDK+EYR WNPFRSKLAA++L G+D IH+ G
Sbjct: 107 GKEDALVTKNLVPGESVYGEKRVSISEGDDKIEYRAWNPFRSKLAAAILGGVDQIHIKPG 166
Query: 182 SKVLYLGASTGTSVSHVSDIVGPTGVVYAVEFAERVGREMLNVAKKRTNIVPIIEDARHP 361
+KVLYLGA++GT+VSHVSDIVGP G+VYAVEF+ R GR+++N+AKKRTNI+P+IEDARHP
Sbjct: 167 AKVLYLGAASGTTVSHVSDIVGPDGLVYAVEFSHRSGRDLINLAKKRTNIIPVIEDARHP 226
Query: 362 HKYRMMINQVDTIFADVAQPDQSRIVAVNADFFLKPGGYAVISLKASCIDSTAEPESAFL 541
HKYRM+I VD IFADVAQPDQ+RIVA+NA FL+ GG+ VIS+KA+CIDSTA E+ F
Sbjct: 227 HKYRMLIAMVDVIFADVAQPDQTRIVALNAHTFLRNGGHFVISIKANCIDSTASAEAVFA 286
Query: 542 SEKDVISKLKFKPDSWLSMEPFERDHKVLIAQYLP 646
SE + + KP L++EP+ERDH V++ Y P
Sbjct: 287 SEVKKMQQENMKPQEQLTLEPYERDHAVVVGVYRP 321
>sp|P22087|FBRL_HUMAN Fibrillarin (34 kDa nucleolar scleroderma antigen)
Length = 321
Score = 300 bits (767), Expect = 3e-81
Identities = 140/215 (65%), Positives = 177/215 (82%)
Frame = +2
Query: 2 GKDETLLTKNFVPGVSVYGEKRIAIGTGDDKVEYRTWNPFRSKLAASVLNGIDSIHMPVG 181
GK++ L+TKN VPG SVYGEKR++I GDDK+EYR WNPFRSKLAA++L G+D IH+ G
Sbjct: 101 GKEDALVTKNLVPGESVYGEKRVSISEGDDKIEYRAWNPFRSKLAAAILGGVDQIHIKPG 160
Query: 182 SKVLYLGASTGTSVSHVSDIVGPTGVVYAVEFAERVGREMLNVAKKRTNIVPIIEDARHP 361
+KVLYLGA++GT+VSHVSDIVGP G+VYAVEF+ R GR+++N+AKKRTNI+P+IEDARHP
Sbjct: 161 AKVLYLGAASGTTVSHVSDIVGPDGLVYAVEFSHRSGRDLINLAKKRTNIIPVIEDARHP 220
Query: 362 HKYRMMINQVDTIFADVAQPDQSRIVAVNADFFLKPGGYAVISLKASCIDSTAEPESAFL 541
HKYRM+I VD IFADVAQPDQ+RIVA+NA FL+ GG+ VIS+KA+CIDSTA E+ F
Sbjct: 221 HKYRMLIAMVDVIFADVAQPDQTRIVALNAHTFLRNGGHFVISIKANCIDSTASAEAVFA 280
Query: 542 SEKDVISKLKFKPDSWLSMEPFERDHKVLIAQYLP 646
SE + + KP L++EP+ERDH V++ Y P
Sbjct: 281 SEVKKMQQENMKPQEQLTLEPYERDHAVVVGVYRP 315
>sp|P22509|FBRL_RAT Fibrillarin (Nucleolar protein 1)
Length = 327
Score = 300 bits (767), Expect = 3e-81
Identities = 140/215 (65%), Positives = 177/215 (82%)
Frame = +2
Query: 2 GKDETLLTKNFVPGVSVYGEKRIAIGTGDDKVEYRTWNPFRSKLAASVLNGIDSIHMPVG 181
GK++ L+TKN VPG SVYGEKR++I GDDK+EYR WNPFRSKLAA++L G+D IH+ G
Sbjct: 107 GKEDALVTKNLVPGESVYGEKRVSISEGDDKIEYRAWNPFRSKLAAAILGGVDQIHIKPG 166
Query: 182 SKVLYLGASTGTSVSHVSDIVGPTGVVYAVEFAERVGREMLNVAKKRTNIVPIIEDARHP 361
+KVLYLGA++GT+VSHVSDIVGP G+VYAVEF+ R GR+++N+AKKRTNI+P+IEDARHP
Sbjct: 167 AKVLYLGAASGTTVSHVSDIVGPDGLVYAVEFSHRSGRDLINLAKKRTNIIPVIEDARHP 226
Query: 362 HKYRMMINQVDTIFADVAQPDQSRIVAVNADFFLKPGGYAVISLKASCIDSTAEPESAFL 541
HKYRM+I VD IFADVAQPDQ+RIVA+NA FL+ GG+ VIS+KA+CIDSTA E+ F
Sbjct: 227 HKYRMLIAMVDVIFADVAQPDQTRIVALNAHTFLRNGGHFVISIKANCIDSTASAEAVFA 286
Query: 542 SEKDVISKLKFKPDSWLSMEPFERDHKVLIAQYLP 646
SE + + KP L++EP+ERDH V++ Y P
Sbjct: 287 SEVKKMQQENMKPQEQLTLEPYERDHAVVVGVYRP 321
>sp|P22232|FBRL_XENLA Fibrillarin
Length = 323
Score = 293 bits (749), Expect = 4e-79
Identities = 138/222 (62%), Positives = 179/222 (80%)
Frame = +2
Query: 2 GKDETLLTKNFVPGVSVYGEKRIAIGTGDDKVEYRTWNPFRSKLAASVLNGIDSIHMPVG 181
GK++ L+TKN VPG SVYGEKRI++ G+ K EYR WNPFRSK+AA++L G+D IH+ G
Sbjct: 103 GKEDALVTKNLVPGESVYGEKRISVEDGEVKTEYRAWNPFRSKIAAAILGGVDQIHIKPG 162
Query: 182 SKVLYLGASTGTSVSHVSDIVGPTGVVYAVEFAERVGREMLNVAKKRTNIVPIIEDARHP 361
KVLYLGA++GT+VSHVSD+VGP G+VYAVEF+ R GR+++NVAKKRTNI+P+IEDARHP
Sbjct: 163 VKVLYLGAASGTTVSHVSDVVGPEGLVYAVEFSHRSGRDLINVAKKRTNIIPVIEDARHP 222
Query: 362 HKYRMMINQVDTIFADVAQPDQSRIVAVNADFFLKPGGYAVISLKASCIDSTAEPESAFL 541
HKYR+++ VD +FADVAQPDQ+RIVA+NA FLK GG+ VIS+KA+CIDSTA PE+ F
Sbjct: 223 HKYRILVGMVDVVFADVAQPDQTRIVALNAHNFLKNGGHFVISIKANCIDSTAAPEAVFA 282
Query: 542 SEKDVISKLKFKPDSWLSMEPFERDHKVLIAQYLPYGPEGKK 667
+E + + KP L++EP+ERDH V++ Y P P+ KK
Sbjct: 283 AEVKKMQQENMKPQEQLTLEPYERDHAVVVGIYRP-PPKQKK 323
>sp|Q22053|FBRL_CAEEL Fibrillarin
Length = 352
Score = 289 bits (739), Expect = 6e-78
Identities = 135/222 (60%), Positives = 179/222 (80%)
Frame = +2
Query: 2 GKDETLLTKNFVPGVSVYGEKRIAIGTGDDKVEYRTWNPFRSKLAASVLNGIDSIHMPVG 181
GK++ L TKN V G SVYGEKR+++ G +EYR WNPFRSKLAAS++ G+++ H+ G
Sbjct: 132 GKEDALATKNMVVGESVYGEKRVSVDDGAGSIEYRVWNPFRSKLAASIMGGLENTHIKPG 191
Query: 182 SKVLYLGASTGTSVSHVSDIVGPTGVVYAVEFAERVGREMLNVAKKRTNIVPIIEDARHP 361
+K+LYLGA++GT+VSH SD+VGP G+VYAVEF+ R GR++L VAKKR N+VPI+EDARHP
Sbjct: 192 TKLLYLGAASGTTVSHCSDVVGPEGIVYAVEFSHRSGRDLLGVAKKRPNVVPIVEDARHP 251
Query: 362 HKYRMMINQVDTIFADVAQPDQSRIVAVNADFFLKPGGYAVISLKASCIDSTAEPESAFL 541
HKYRM++ VD IF+DVAQPDQ+RIVA+NA FL+ GG+AVIS+KA+CIDSTAEPE+ F
Sbjct: 252 HKYRMLVGMVDVIFSDVAQPDQARIVALNAQNFLRNGGHAVISIKANCIDSTAEPEAVFA 311
Query: 542 SEKDVISKLKFKPDSWLSMEPFERDHKVLIAQYLPYGPEGKK 667
E + + + KFKP +++EP+ERDH V++A Y P +GKK
Sbjct: 312 GEVNKLKEEKFKPLEQVTLEPYERDHAVVVAVYRPV--KGKK 351
>sp|Q9FEF8|FBRL1_ARATH Fibrillarin-1 (SKP1 interacting partner 7)
Length = 308
Score = 276 bits (705), Expect = 5e-74
Identities = 131/214 (61%), Positives = 172/214 (80%), Gaps = 1/214 (0%)
Frame = +2
Query: 2 GKDETLLTKNFVPGVSVYGEKRIAIGTGDD-KVEYRTWNPFRSKLAASVLNGIDSIHMPV 178
GK++ L+TKN VPG +VY EKRI++ D KVEYR WNPFRSKLAA++L G+D+I +
Sbjct: 84 GKEDALVTKNLVPGEAVYNEKRISVQNEDGTKVEYRVWNPFRSKLAAAILGGVDNIWIKP 143
Query: 179 GSKVLYLGASTGTSVSHVSDIVGPTGVVYAVEFAERVGREMLNVAKKRTNIVPIIEDARH 358
G+KVLYLGA++GT+VSHVSD+VGP G VYAVEF+ R GR+++N+AKKRTN++PIIEDARH
Sbjct: 144 GAKVLYLGAASGTTVSHVSDLVGPEGCVYAVEFSHRSGRDLVNMAKKRTNVIPIIEDARH 203
Query: 359 PHKYRMMINQVDTIFADVAQPDQSRIVAVNADFFLKPGGYAVISLKASCIDSTAEPESAF 538
P KYRM++ VD IF+DVAQPDQ+RI+A+NA FFLK GG+ VIS+KA+CIDST E+ F
Sbjct: 204 PAKYRMLVGMVDVIFSDVAQPDQARILALNASFFLKTGGHFVISIKANCIDSTVAAEAVF 263
Query: 539 LSEKDVISKLKFKPDSWLSMEPFERDHKVLIAQY 640
SE + + +FKP +++EPFERDH ++ Y
Sbjct: 264 QSEVKKLQQEQFKPAEQVTLEPFERDHACVVGGY 297
>sp|Q94AH9|FBRL2_ARATH Fibrillarin-2 (Fibrillarin-like protein)
Length = 320
Score = 273 bits (698), Expect = 3e-73
Identities = 131/225 (58%), Positives = 176/225 (78%), Gaps = 2/225 (0%)
Frame = +2
Query: 2 GKDETLLTKNFVPGVSVYGEKRIAIGTGDD-KVEYRTWNPFRSKLAASVLNGIDSIHMPV 178
GK++ L+TKN VPG +VY EKRI++ D K EYR WNPFRSKLAA++L G+D+I +
Sbjct: 95 GKEDALVTKNLVPGEAVYNEKRISVQNEDGTKTEYRVWNPFRSKLAAAILGGVDNIWIKP 154
Query: 179 GSKVLYLGASTGTSVSHVSDIVGPTGVVYAVEFAERVGREMLNVAKKRTNIVPIIEDARH 358
G+KVLYLGA++GT+VSHVSD+VGP G VYAVEF+ R GR+++N+AKKRTN++PIIEDARH
Sbjct: 155 GAKVLYLGAASGTTVSHVSDLVGPEGCVYAVEFSHRSGRDLVNMAKKRTNVIPIIEDARH 214
Query: 359 PHKYRMMINQVDTIFADVAQPDQSRIVAVNADFFLKPGGYAVISLKASCIDSTAEPESAF 538
P KYRM++ VD IF+DVAQPDQ+RI+A+NA +FLK GG+ VIS+KA+CIDST E+ F
Sbjct: 215 PAKYRMLVGMVDVIFSDVAQPDQARILALNASYFLKSGGHFVISIKANCIDSTVPAEAVF 274
Query: 539 LSEKDVISKLKFKPDSWLSMEPFERDHKVLIAQY-LPYGPEGKKA 670
+E + + +FKP +++EPFERDH ++ Y +P P+ A
Sbjct: 275 QTEVKKLQQEQFKPAEQVTLEPFERDHACVVGGYRMPKKPKAATA 319
>sp|P35551|FBRL_SCHPO Fibrillarin
Length = 305
Score = 270 bits (690), Expect = 3e-72
Identities = 129/215 (60%), Positives = 170/215 (79%), Gaps = 1/215 (0%)
Frame = +2
Query: 2 GKDETLLTKNFVPGVSVYGEKRIAIGTGDD-KVEYRTWNPFRSKLAASVLNGIDSIHMPV 178
GK++ L+T+N VPG SVY EKRI++ + D KVEYR WNPFRSKLAA +L G+D+I++
Sbjct: 88 GKEDLLVTRNLVPGESVYNEKRISVDSPDGTKVEYRVWNPFRSKLAAGILGGLDNIYIKP 147
Query: 179 GSKVLYLGASTGTSVSHVSDIVGPTGVVYAVEFAERVGREMLNVAKKRTNIVPIIEDARH 358
G++VLYLGA+ GTSVSHV+D+VGP G+VYAVEF+ R GR++LN+AKKRTN++PI+EDARH
Sbjct: 148 GARVLYLGAANGTSVSHVADVVGPEGLVYAVEFSHRSGRDLLNMAKKRTNVIPIVEDARH 207
Query: 359 PHKYRMMINQVDTIFADVAQPDQSRIVAVNADFFLKPGGYAVISLKASCIDSTAEPESAF 538
KYRM++ VD +FADVAQPDQ+RIVA+NA FLK G VIS+KASCIDSTA+ F
Sbjct: 208 VQKYRMLVGMVDVVFADVAQPDQARIVALNAAAFLKNEGGVVISVKASCIDSTADAAVVF 267
Query: 539 LSEKDVISKLKFKPDSWLSMEPFERDHKVLIAQYL 643
E + + K KP L++EP+ERDH +++ +YL
Sbjct: 268 AREVKKMQEEKIKPQEQLTLEPYERDHCIIVGKYL 302
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 88,165,516
Number of Sequences: 369166
Number of extensions: 1895566
Number of successful extensions: 6132
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 5914
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6070
length of database: 68,354,980
effective HSP length: 107
effective length of database: 48,588,335
effective search space used: 6122130210
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)