Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_016_F16
(397 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q95135|EAA3_BOVIN Excitatory amino acid transporter 3 (S... 72 4e-13
sp|P51906|EAA3_MOUSE Excitatory amino acid transporter 3 (S... 72 4e-13
sp|P31597|EAA3_RABIT Excitatory amino acid transporter 3 (S... 72 5e-13
sp|P51907|EAA3_RAT Excitatory amino acid transporter 3 (Sod... 71 9e-13
sp|P43005|EAA3_HUMAN Excitatory amino acid transporter 3 (S... 70 2e-12
sp|P43004|EAA2_HUMAN Excitatory amino acid transporter 2 (S... 67 1e-11
sp|P43006|EAA2_MOUSE Excitatory amino acid transporter 2 (S... 67 1e-11
sp|P31596|EAA2_RAT Excitatory amino acid transporter 2 (Sod... 67 1e-11
sp|O57321|EAA1_AMBTI Excitatory amino acid transporter 1 (S... 66 3e-11
sp|Q10901|EAA1_CAEEL Excitatory amino acid transporter (Sod... 65 5e-11
>sp|Q95135|EAA3_BOVIN Excitatory amino acid transporter 3 (Sodium-dependent
glutamate/aspartate transporter 3) (Excitatory
amino-acid carrier 1) (Renal high affinity glutamate
transporter EAAC1)
Length = 524
Score = 72.0 bits (175), Expect = 4e-13
Identities = 37/64 (57%), Positives = 45/64 (70%), Gaps = 3/64 (4%)
Frame = +1
Query: 1 DITLILAVDWLLDRVRTSINVLGDAFGAGIVDHLCKKELEAITTGNENEMV---TLDQNE 171
D+TLI+AVDWLLDR RT +NVLGDAFG GIV+ L KKELE + +E +V TL+
Sbjct: 432 DVTLIIAVDWLLDRFRTMVNVLGDAFGTGIVEKLSKKELEQMDVSSEVNIVNPFTLESTA 491
Query: 172 SQNE 183
NE
Sbjct: 492 LDNE 495
>sp|P51906|EAA3_MOUSE Excitatory amino acid transporter 3 (Sodium-dependent
glutamate/aspartate transporter 3) (Excitatory
amino-acid carrier 1)
Length = 523
Score = 72.0 bits (175), Expect = 4e-13
Identities = 37/70 (52%), Positives = 47/70 (67%), Gaps = 8/70 (11%)
Frame = +1
Query: 1 DITLILAVDWLLDRVRTSINVLGDAFGAGIVDHLCKKELEAITTGNENEMV--------T 156
D+TLI+AVDWLLDR RT +NVLGDAFG GIV+ L KKELE + +E +V T
Sbjct: 431 DVTLIIAVDWLLDRFRTMVNVLGDAFGTGIVEKLSKKELEQMDVSSEVNIVNPFALEPTT 490
Query: 157 LDQNESQNER 186
LD +S ++
Sbjct: 491 LDNEDSDTKK 500
>sp|P31597|EAA3_RABIT Excitatory amino acid transporter 3 (Sodium-dependent
glutamate/aspartate transporter 3) (Excitatory
amino-acid carrier 1)
Length = 524
Score = 71.6 bits (174), Expect = 5e-13
Identities = 37/70 (52%), Positives = 47/70 (67%), Gaps = 8/70 (11%)
Frame = +1
Query: 1 DITLILAVDWLLDRVRTSINVLGDAFGAGIVDHLCKKELEAITTGNENEMV--------T 156
D+TLI+AVDWLLDR RT +NVLGDAFG GIV+ L KKELE + +E +V T
Sbjct: 432 DVTLIIAVDWLLDRFRTVVNVLGDAFGTGIVEKLSKKELEQMDVSSEVNIVNPFALESAT 491
Query: 157 LDQNESQNER 186
LD +S ++
Sbjct: 492 LDNEDSDTKK 501
>sp|P51907|EAA3_RAT Excitatory amino acid transporter 3 (Sodium-dependent
glutamate/aspartate transporter 3) (Excitatory
amino-acid carrier 1)
Length = 523
Score = 70.9 bits (172), Expect = 9e-13
Identities = 33/51 (64%), Positives = 40/51 (78%)
Frame = +1
Query: 1 DITLILAVDWLLDRVRTSINVLGDAFGAGIVDHLCKKELEAITTGNENEMV 153
D+TLI+AVDWLLDR RT +NVLGDAFG GIV+ L KKELE + +E +V
Sbjct: 431 DVTLIIAVDWLLDRFRTMVNVLGDAFGTGIVEKLSKKELEQVDVSSEVNIV 481
>sp|P43005|EAA3_HUMAN Excitatory amino acid transporter 3 (Sodium-dependent
glutamate/aspartate transporter 3) (Excitatory
amino-acid carrier 1) (Neuronal and epithelial glutamate
transporter)
Length = 524
Score = 70.1 bits (170), Expect = 2e-12
Identities = 33/51 (64%), Positives = 40/51 (78%)
Frame = +1
Query: 1 DITLILAVDWLLDRVRTSINVLGDAFGAGIVDHLCKKELEAITTGNENEMV 153
D+TLI+AVDWLLDR RT +NVLGDAFG GIV+ L KKELE + +E +V
Sbjct: 432 DVTLIIAVDWLLDRFRTMVNVLGDAFGTGIVEKLSKKELEQMDVSSEVNIV 482
>sp|P43004|EAA2_HUMAN Excitatory amino acid transporter 2 (Sodium-dependent
glutamate/aspartate transporter 2)
Length = 574
Score = 67.0 bits (162), Expect = 1e-11
Identities = 30/42 (71%), Positives = 38/42 (90%)
Frame = +1
Query: 1 DITLILAVDWLLDRVRTSINVLGDAFGAGIVDHLCKKELEAI 126
DI+L++AVDWLLDR+RTS+NV+GD+FGAGIV HL K EL+ I
Sbjct: 463 DISLLVAVDWLLDRMRTSVNVVGDSFGAGIVYHLSKSELDTI 504
>sp|P43006|EAA2_MOUSE Excitatory amino acid transporter 2 (Sodium-dependent
glutamate/aspartate transporter 2) (GLT-1)
Length = 572
Score = 67.0 bits (162), Expect = 1e-11
Identities = 30/42 (71%), Positives = 38/42 (90%)
Frame = +1
Query: 1 DITLILAVDWLLDRVRTSINVLGDAFGAGIVDHLCKKELEAI 126
DI+L++AVDWLLDR+RTS+NV+GD+FGAGIV HL K EL+ I
Sbjct: 462 DISLLVAVDWLLDRMRTSVNVVGDSFGAGIVYHLSKSELDTI 503
>sp|P31596|EAA2_RAT Excitatory amino acid transporter 2 (Sodium-dependent
glutamate/aspartate transporter 2) (GLUT-R) (GLT-1)
Length = 573
Score = 67.0 bits (162), Expect = 1e-11
Identities = 30/42 (71%), Positives = 38/42 (90%)
Frame = +1
Query: 1 DITLILAVDWLLDRVRTSINVLGDAFGAGIVDHLCKKELEAI 126
DI+L++AVDWLLDR+RTS+NV+GD+FGAGIV HL K EL+ I
Sbjct: 462 DISLLVAVDWLLDRMRTSVNVVGDSFGAGIVYHLSKSELDTI 503
>sp|O57321|EAA1_AMBTI Excitatory amino acid transporter 1 (SEAAT1)
Length = 543
Score = 65.9 bits (159), Expect = 3e-11
Identities = 38/69 (55%), Positives = 46/69 (66%), Gaps = 6/69 (8%)
Frame = +1
Query: 1 DITLILAVDWLLDRVRTSINVLGDAFGAGIVDHLCKKELEA--ITTGN----ENEMVTLD 162
DITLI+AVDW LDR+RT+ NVLGD+ GAGIV+HL + EL++ GN ENEM
Sbjct: 465 DITLIIAVDWFLDRLRTTTNVLGDSLGAGIVEHLSRHELQSGDAEMGNSVIEENEMKKPY 524
Query: 163 QNESQNERL 189
Q SQ L
Sbjct: 525 QLVSQENEL 533
>sp|Q10901|EAA1_CAEEL Excitatory amino acid transporter (Sodium-dependent glutamate/
aspartate transporter)
Length = 503
Score = 65.1 bits (157), Expect = 5e-11
Identities = 30/41 (73%), Positives = 36/41 (87%)
Frame = +1
Query: 1 DITLILAVDWLLDRVRTSINVLGDAFGAGIVDHLCKKELEA 123
D++LI+AVDWLLDR+RTSINVLGDA GAGIV H K +L+A
Sbjct: 426 DVSLIVAVDWLLDRIRTSINVLGDAMGAGIVYHYSKADLDA 466
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 31,817,896
Number of Sequences: 369166
Number of extensions: 448454
Number of successful extensions: 1196
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 1177
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 1196
length of database: 68,354,980
effective HSP length: 97
effective length of database: 50,435,685
effective search space used: 1714813290
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)