Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_016_E23
(873 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P10587|MYH11_CHICK Myosin-11 (Myosin heavy chain, gizzar... 66 1e-10
sp|P35749|MYH11_HUMAN Myosin-11 (Myosin heavy chain, smooth... 61 4e-09
sp|O08638|MYH11_MOUSE Myosin-11 (Myosin heavy chain, smooth... 61 4e-09
sp|P35748|MYH11_RABIT Myosin-11 (Myosin heavy chain, smooth... 61 5e-09
sp|Q8VDD5|MYH9_MOUSE Myosin-9 (Myosin heavy chain, nonmuscl... 56 1e-07
sp|Q62812|MYH9_RAT Myosin-9 (Myosin heavy chain, nonmuscle ... 55 3e-07
sp|P35579|MYH9_HUMAN Myosin-9 (Myosin heavy chain, nonmuscl... 55 3e-07
sp|Q12267|SMC4_YEAST Structural maintenance of chromosome 4 54 4e-07
sp|P14105|MYH9_CHICK Myosin-9 (Myosin heavy chain, nonmuscl... 54 7e-07
sp|P93203|MFP1_LYCES MAR binding filament-like protein 1 54 7e-07
>sp|P10587|MYH11_CHICK Myosin-11 (Myosin heavy chain, gizzard smooth muscle)
Length = 1979
Score = 66.2 bits (160), Expect = 1e-10
Identities = 76/304 (25%), Positives = 136/304 (44%), Gaps = 18/304 (5%)
Frame = +2
Query: 5 KSTILENLNKDMRDQTMEYEETKRLIEEDADREIL-------DTKIK-YERRLREERESN 160
+S L+ K M+ Q ++ EE +L EE+A R+ L D KIK E + + N
Sbjct: 943 RSQQLQAEKKKMQQQMLDLEE--QLEEEEAARQKLQLEKVTADGKIKKMEDDILIMEDQN 1000
Query: 161 ARLKGETGIMKKKFASLXXXXXXXXXXXXXFQTETQKLENVIRNLEKDKVGLKKEIQERD 340
+L E +++++ + L K E++I LE V LKKE + R
Sbjct: 1001 NKLTKERKLLEERVSDLTTNLAEEEEKAKNLTKLKNKHESMISELE---VRLKKEEKSRQ 1057
Query: 341 ETIQDKEKRIYDLKKKNQELDKFKFVLDYKIKELKKQIEpreLEIQSAKEQIQEMESELE 520
E + K K L+ ++ +L + L +I ELK Q+ +E E+Q+A ++++ S+
Sbjct: 1058 ELEKIKRK----LEGESSDLHEQIAELQAQIAELKAQLAKKEEELQAALARLEDETSQKN 1113
Query: 521 RFSKHNSQLSLNIXXXXXXXXXXXXXXXXXRQATRDVEAQVRRFKTDLYNCVSYI---QD 691
K +L +I + RD+ ++ KT+L + + Q+
Sbjct: 1114 NALKKIRELESHISDLQEDLESEKAARNKAEKQKRDLSEELEALKTELEDTLDTTATQQE 1173
Query: 692 PKGLKDSIVALYKKHIQEDV-TSEASVDADIQK------EFTRQREHLERSVASLRKNYR 850
+ ++ V + K+ ++E+ T EA V QK E T Q E +R+ A+L K +
Sbjct: 1174 LRAKREQEVTVLKRALEEETRTHEAQVQEMRQKHTQAVEELTEQLEQFKRAKANLDKTKQ 1233
Query: 851 KIQK 862
++K
Sbjct: 1234 TLEK 1237
Score = 44.3 bits (103), Expect = 4e-04
Identities = 42/183 (22%), Positives = 93/183 (50%), Gaps = 14/183 (7%)
Frame = +2
Query: 17 LENLNKDMRDQTMEY---EETKRLIEEDADREILDTKIKYERRLREERESNARLKGETGI 187
+E+L + ++ Y E+TK ++++ D ++D + +R+L E + K + +
Sbjct: 1407 IESLTQQFEEKAASYDKLEKTKNRLQQELDDLVVD--LDNQRQLVSNLEKKQK-KFDQML 1463
Query: 188 MKKKFASLXXXXXXXXXXXXXFQTETQKLENVIRNLEKDKVGLKKEIQERDETIQDKEKR 367
++K S + ET+ L ++ R LE + + K+E++ ++ ++ + +
Sbjct: 1464 AEEKNISSKYADERDRAEAEAREKETKAL-SLARALE-EALEAKEELERTNKMLKAEMED 1521
Query: 368 IY----DLKKKNQELDKFKFVLDYKIKELKKQIEpreLEIQSAKE-------QIQEMESE 514
+ D+ K EL+K K L+ +++E+K Q+E E E+Q+A++ +Q M+S+
Sbjct: 1522 LVSSKDDVGKNVHELEKSKRTLEQQVEEMKTQLEELEDELQAAEDAKLRLEVNMQAMKSQ 1581
Query: 515 LER 523
ER
Sbjct: 1582 FER 1584
Score = 32.0 bits (71), Expect = 2.3
Identities = 27/123 (21%), Positives = 50/123 (40%), Gaps = 29/123 (23%)
Frame = +2
Query: 266 QKLENVIRNLEKDKVGLKKEIQERDETIQDK---------------EKRIYDLKKKNQEL 400
QK EN + LE+ L+ ++QE + ++ K E+++ ++ Q
Sbjct: 1787 QKNENARQQLERQNKELRSKLQEMEGAVKSKFKSTIAALEAKIASLEEQLEQEAREKQAA 1846
Query: 401 DKFKFVLDYKIKE--------------LKKQIEpreLEIQSAKEQIQEMESELERFSKHN 538
K D K+K+ K Q E L ++ K Q++E E E +R + +
Sbjct: 1847 AKTLRQKDKKLKDALLQVEDERKQAEQYKDQAEKGNLRLKQLKRQLEEAEEESQRINANR 1906
Query: 539 SQL 547
+L
Sbjct: 1907 RKL 1909
>sp|P35749|MYH11_HUMAN Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC)
Length = 1972
Score = 61.2 bits (147), Expect = 4e-09
Identities = 72/300 (24%), Positives = 131/300 (43%), Gaps = 18/300 (6%)
Frame = +2
Query: 17 LENLNKDMRDQTMEYEETKRLIEEDADREILDT-KIKYERRLREERES-------NARLK 172
L+ K M Q ++ EE +L EE+A R+ L K+ E ++++ + N +L
Sbjct: 941 LQAERKKMAQQMLDLEE--QLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLS 998
Query: 173 GETGIMKKKFASLXXXXXXXXXXXXXFQTETQKLENVIRNLEKDKVGLKKEIQERDETIQ 352
E +++++ + L K E++I LE V LKKE + R E +
Sbjct: 999 KERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELE---VRLKKEEKSRQELEK 1055
Query: 353 DKEKRIYDLKKKNQELDKFKFVLDYKIKELKKQIEpreLEIQSAKEQIQEMESELERFSK 532
K K D ++++ L +I ELK Q+ +E E+Q+A ++ + ++ K
Sbjct: 1056 LKRKLEGDASDFHEQIAD----LQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALK 1111
Query: 533 HNSQLSLNIXXXXXXXXXXXXXXXXXRQATRDVEAQVRRFKTDLYNCVSYI---QDPKGL 703
+L +I + RD+ ++ KT+L + + Q+ +
Sbjct: 1112 KIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAK 1171
Query: 704 KDSIVALYKKHIQEDVTS-EASVDADIQK------EFTRQREHLERSVASLRKNYRKIQK 862
++ V + KK + E+ S EA V QK E T Q E +R+ A+L KN + ++K
Sbjct: 1172 REQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEK 1231
Score = 41.2 bits (95), Expect = 0.004
Identities = 39/175 (22%), Positives = 88/175 (50%), Gaps = 7/175 (4%)
Frame = +2
Query: 17 LENLNKDMRDQTMEY---EETKRLIEEDADREILDTKIKYERRLREERESNARLKGETGI 187
+ENL + ++ Y E+TK ++++ D ++D + +R+L E R K + +
Sbjct: 1401 IENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVD--LDNQRQLVSNLEKKQR-KFDQLL 1457
Query: 188 MKKKFASLXXXXXXXXXXXXXFQTETQKLENVIRNLEKDKVGLKKEIQERDETIQDKEKR 367
++K S + ET+ L ++ R LE + + K+E++ ++ ++ + +
Sbjct: 1458 AEEKNISSKYADERDRAEAEAREKETKAL-SLARALE-EALEAKEELERTNKMLKAEMED 1515
Query: 368 IY----DLKKKNQELDKFKFVLDYKIKELKKQIEpreLEIQSAKEQIQEMESELE 520
+ D+ K EL+K K L+ +++E+K Q+E E E+Q+ ++ +E ++
Sbjct: 1516 LVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQ 1570
Score = 33.5 bits (75), Expect = 0.79
Identities = 35/191 (18%), Positives = 73/191 (38%), Gaps = 27/191 (14%)
Frame = +2
Query: 65 ETKRLIEEDAD-----REILDTKIKYERRLREERESNARLKGETGIMKKKFASLXXXXXX 229
E + L EE A + D K + E R+ + E +G M +
Sbjct: 1709 EKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQ 1768
Query: 230 XXXXXXXFQTETQKLENVIRNLEKDKVGLKKEIQERDETIQDK---------------EK 364
++ QK E+ + LE+ L+ ++ E + ++ K E+
Sbjct: 1769 LSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEE 1828
Query: 365 RIYDLKKKNQELDKFKFVLDYKIKELKKQIEpreLEIQSAKEQ-------IQEMESELER 523
++ ++ Q K D K+KE+ Q+E + KEQ +++++ +LE
Sbjct: 1829 QVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEE 1888
Query: 524 FSKHNSQLSLN 556
+ + +++ N
Sbjct: 1889 AEEESQRINAN 1899
Score = 32.3 bits (72), Expect = 1.8
Identities = 25/137 (18%), Positives = 62/137 (45%)
Frame = +2
Query: 428 KIKELKKQIEpreLEIQSAKEQIQEMESELERFSKHNSQLSLNIXXXXXXXXXXXXXXXX 607
++ +++++ +E E+Q KE+ Q+ E+EL+ + +SQL+
Sbjct: 846 QVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAE 905
Query: 608 XRQATRDVEAQVRRFKTDLYNCVSYIQDPKGLKDSIVALYKKHIQEDVTSEASVDADIQK 787
+ + A+ + + L+ + +++ + + A KK Q+ + E ++ ++
Sbjct: 906 AEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLE---EE 962
Query: 788 EFTRQREHLERSVASLR 838
E RQ+ LE+ A +
Sbjct: 963 EAARQKLQLEKVTAEAK 979
Score = 30.8 bits (68), Expect = 5.1
Identities = 38/182 (20%), Positives = 71/182 (39%), Gaps = 9/182 (4%)
Frame = +2
Query: 32 KDMRDQTMEYEETKRLIEEDADREILDTKIKYERR---------LREERESNARLKGETG 184
K RD E E K +E+ D +++ +R L EE S+ + +
Sbjct: 1139 KQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSH---EAQVQ 1195
Query: 185 IMKKKFASLXXXXXXXXXXXXXFQTETQKLENVIRNLEKDKVGLKKEIQERDETIQDKEK 364
M++K A F+ L+ + LEK+ L E++ + Q+ E
Sbjct: 1196 EMRQKHAQAVEELTEQLEQ---FKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEH 1252
Query: 365 RIYDLKKKNQELDKFKFVLDYKIKELKKQIEpreLEIQSAKEQIQEMESELERFSKHNSQ 544
+ L+ + QEL + EL ++ + E++S + E E + + +K +
Sbjct: 1253 KKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVAS 1312
Query: 545 LS 550
LS
Sbjct: 1313 LS 1314
>sp|O08638|MYH11_MOUSE Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC)
Length = 1972
Score = 61.2 bits (147), Expect = 4e-09
Identities = 72/300 (24%), Positives = 132/300 (44%), Gaps = 18/300 (6%)
Frame = +2
Query: 17 LENLNKDMRDQTMEYEETKRLIEEDADREILDT-KIKYERRLREERES-------NARLK 172
L+ K M Q ++ EE +L EE+A R+ L K+ E ++++ + N++L
Sbjct: 941 LQAERKKMAQQMLDLEE--QLEEEEAARQKLQLEKVTAEAKIKKLEDDILVMDDQNSKLS 998
Query: 173 GETGIMKKKFASLXXXXXXXXXXXXXFQTETQKLENVIRNLEKDKVGLKKEIQERDETIQ 352
E +++++ + L K E++I LE V LKKE + R E +
Sbjct: 999 KERKLLEERVSDLTTNLAEEEEKAKNLTKLKSKHESMISELE---VRLKKEEKSRQELEK 1055
Query: 353 DKEKRIYDLKKKNQELDKFKFVLDYKIKELKKQIEpreLEIQSAKEQIQEMESELERFSK 532
K K D ++++ L +I ELK Q+ +E E+Q+A ++ E ++ K
Sbjct: 1056 LKRKLEGDASDFHEQIAD----LQAQIAELKMQLAKKEEELQAALARLDEEIAQKNNALK 1111
Query: 533 HNSQLSLNIXXXXXXXXXXXXXXXXXRQATRDVEAQVRRFKTDLYNCVSYI---QDPKGL 703
+L +I + RD+ ++ KT+L + + Q+ +
Sbjct: 1112 KIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAK 1171
Query: 704 KDSIVALYKKHIQEDVTS-EASVDADIQK------EFTRQREHLERSVASLRKNYRKIQK 862
++ V + KK + E+ S EA V QK E T Q E +R+ A+L K+ + ++K
Sbjct: 1172 REQEVTVLKKALDEETRSHEAQVQEMRQKHTQAVEELTEQLEQFKRAKANLDKSKQTLEK 1231
Score = 43.1 bits (100), Expect = 0.001
Identities = 33/182 (18%), Positives = 83/182 (45%), Gaps = 1/182 (0%)
Frame = +2
Query: 17 LENLNKDMRDQTMEYEETKRLIEEDADREILDTKIKYERRL-REERESNARLKGETGIMK 193
+E ++ +R T++ E+ E +R ++L R+ +E ++L+ G +K
Sbjct: 1752 MEAMSDRVRKATLQAEQLSN--ELATERSTAQKNESARQQLERQNKELRSKLQEVEGAVK 1809
Query: 194 KKFASLXXXXXXXXXXXXXFQTETQKLENVIRNLEKDKVGLKKEIQERDETIQDKEKRIY 373
K S + + +LE + ++K K ++++D+ +++ ++
Sbjct: 1810 AKLKSTVAA----------LEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEVLLQVE 1859
Query: 374 DLKKKNQELDKFKFVLDYKIKELKKQIEpreLEIQSAKEQIQEMESELERFSKHNSQLSL 553
D +K ++ + + K+K+LK+Q+E E E Q ++++ EL+ ++ N +
Sbjct: 1860 DERKMAEQYKEQAEKGNTKVKQLKRQLEEAEEESQCINANRRKLQRELDEATESNEAMGR 1919
Query: 554 NI 559
+
Sbjct: 1920 EV 1921
Score = 38.1 bits (87), Expect = 0.032
Identities = 38/181 (20%), Positives = 88/181 (48%), Gaps = 14/181 (7%)
Frame = +2
Query: 20 ENLNKDMRDQTMEYEE----------TKRLIEEDADREILDTKIKYERRLREERESNARL 169
+ L K+M + +YEE TK ++++ D ++D + +R+L E +
Sbjct: 1395 KRLQKEMEGLSQQYEEKAAAYDKLEKTKNRLQQELDDLVVD--LDNQRQLVSNLEKKQK- 1451
Query: 170 KGETGIMKKKFASLXXXXXXXXXXXXXFQTETQKLENVIRNLEKDKVGLKKEIQERDETI 349
K + + ++K S + ET+ L ++ R LE + + K+E++ ++ +
Sbjct: 1452 KFDQLLAEEKNISSKYADERDRAEAEAREKETKAL-SLARALE-EALEAKEELERTNKML 1509
Query: 350 QDKEKRIY----DLKKKNQELDKFKFVLDYKIKELKKQIEpreLEIQSAKEQIQEMESEL 517
+ + + + D+ K EL+K K L+ +++E+K Q+E E ++Q+ ++ +E +
Sbjct: 1510 KAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEESEDDVQATEDAKLRLEVNM 1569
Query: 518 E 520
+
Sbjct: 1570 Q 1570
>sp|P35748|MYH11_RABIT Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC)
Length = 1972
Score = 60.8 bits (146), Expect = 5e-09
Identities = 71/300 (23%), Positives = 131/300 (43%), Gaps = 18/300 (6%)
Frame = +2
Query: 17 LENLNKDMRDQTMEYEETKRLIEEDADREILDT-KIKYERRLREERES-------NARLK 172
L+ K M Q ++ EE +L EE+A R+ L K+ E ++++ + N +L
Sbjct: 941 LQAERKKMAQQMLDLEE--QLEEEEAARQKLQLEKVTAEAKIKKLEDDILVMDDQNNKLS 998
Query: 173 GETGIMKKKFASLXXXXXXXXXXXXXFQTETQKLENVIRNLEKDKVGLKKEIQERDETIQ 352
E +++++ + L K E++I LE V LKKE + R E +
Sbjct: 999 KERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELE---VRLKKEEKSRQELEK 1055
Query: 353 DKEKRIYDLKKKNQELDKFKFVLDYKIKELKKQIEpreLEIQSAKEQIQEMESELERFSK 532
K K + ++++ L +I ELK Q+ +E E+Q+A ++++ S+ K
Sbjct: 1056 LKRKMDGEASDLHEQIAD----LQAQIAELKMQLAKKEEELQAALARLEDETSQKNNALK 1111
Query: 533 HNSQLSLNIXXXXXXXXXXXXXXXXXRQATRDVEAQVRRFKTDLYNCVSYI---QDPKGL 703
+L +I + RD+ ++ KT+L + + Q+ +
Sbjct: 1112 KIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDTTATQQELRAK 1171
Query: 704 KDSIVALYKKHIQEDVTS-EASVDADIQK------EFTRQREHLERSVASLRKNYRKIQK 862
++ V + KK + E+ S EA V QK E T Q E +R+ A+L K + ++K
Sbjct: 1172 REQEVTVLKKALDEETRSHEAQVQEMRQKHTQVVEELTEQLEQFKRAKANLDKTKQTLEK 1231
Score = 46.2 bits (108), Expect = 1e-04
Identities = 28/140 (20%), Positives = 67/140 (47%)
Frame = +2
Query: 140 REERESNARLKGETGIMKKKFASLXXXXXXXXXXXXXFQTETQKLENVIRNLEKDKVGLK 319
R+ +E ++L+ G +K KF S + + +LE + ++K
Sbjct: 1792 RQNKELKSKLQEMEGAVKSKFKSTIAA----------LEAKIAQLEEQVEQEAREKQAAA 1841
Query: 320 KEIQERDETIQDKEKRIYDLKKKNQELDKFKFVLDYKIKELKKQIEpreLEIQSAKEQIQ 499
K +++RD+ +++ ++ D +K ++ + + K+K+LK+Q+E E E Q +
Sbjct: 1842 KALKQRDKKLKEMLLQVEDERKMAEQYKEQAEKGNAKVKQLKRQLEEAEEESQRINANRR 1901
Query: 500 EMESELERFSKHNSQLSLNI 559
+++ EL+ ++ N + +
Sbjct: 1902 KLQRELDEATESNEAMGREV 1921
Score = 38.1 bits (87), Expect = 0.032
Identities = 37/175 (21%), Positives = 88/175 (50%), Gaps = 7/175 (4%)
Frame = +2
Query: 17 LENLNKDMRDQTMEY---EETKRLIEEDADREILDTKIKYERRLREERESNARLKGETGI 187
+E+L + ++ Y E+TK ++++ D ++D + +R+L E + K + +
Sbjct: 1401 IESLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVD--LDNQRQLVSNLEKKQK-KFDQLL 1457
Query: 188 MKKKFASLXXXXXXXXXXXXXFQTETQKLENVIRNLEKDKVGLKKEIQERDETIQDKEKR 367
++K S + ET+ L ++ R LE + + K+E++ ++ ++ + +
Sbjct: 1458 AEEKNISSKYADERDRAEAEAREKETKAL-SLARALE-EALEAKEELERTNKMLKAEMED 1515
Query: 368 IY----DLKKKNQELDKFKFVLDYKIKELKKQIEpreLEIQSAKEQIQEMESELE 520
+ D+ K EL+K K L+ +++E+K Q+E E E+Q+ ++ +E ++
Sbjct: 1516 LVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQ 1570
Score = 33.5 bits (75), Expect = 0.79
Identities = 26/137 (18%), Positives = 62/137 (45%)
Frame = +2
Query: 428 KIKELKKQIEpreLEIQSAKEQIQEMESELERFSKHNSQLSLNIXXXXXXXXXXXXXXXX 607
++ +++++ +E E+Q KE+ Q+ ESEL+ + ++QLS
Sbjct: 846 QVTRQEEEMQAKEDELQKIKERQQKAESELQELQQKHTQLSEEKNLLQEQLQAETELYAE 905
Query: 608 XRQATRDVEAQVRRFKTDLYNCVSYIQDPKGLKDSIVALYKKHIQEDVTSEASVDADIQK 787
+ + A+ + + L+ + +++ + + A KK Q+ + E ++ ++
Sbjct: 906 AEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLE---EE 962
Query: 788 EFTRQREHLERSVASLR 838
E RQ+ LE+ A +
Sbjct: 963 EAARQKLQLEKVTAEAK 979
Score = 31.6 bits (70), Expect = 3.0
Identities = 35/201 (17%), Positives = 76/201 (37%)
Frame = +2
Query: 254 QTETQKLENVIRNLEKDKVGLKKEIQERDETIQDKEKRIYDLKKKNQELDKFKFVLDYKI 433
Q E + + ++ E + L KE+ +QD ++ + QE + K + K+
Sbjct: 1286 QNEVESVTGMLSEAEGKAIKLAKEVASLGSQLQDTQELL-------QEETRQKLNVSTKL 1338
Query: 434 KELKKQIEpreLEIQSAKEQIQEMESELERFSKHNSQLSLNIXXXXXXXXXXXXXXXXXR 613
++L E E S +EQ+ E + +H S L++ +
Sbjct: 1339 RQL-------EDERNSLQEQLDEEMEAKQNLERHISTLNIQL-------SDSKKKLQDFA 1384
Query: 614 QATRDVEAQVRRFKTDLYNCVSYIQDPKGLKDSIVALYKKHIQEDVTSEASVDADIQKEF 793
+E +RF+ ++ + ++ D + K +Q+++ + VD D Q++
Sbjct: 1385 STVESLEEGKKRFQKEIESLTQQYEEKAAAYDKLEKT-KNRLQQEL-DDLVVDLDNQRQL 1442
Query: 794 TRQREHLERSVASLRKNYRKI 856
E ++ L + I
Sbjct: 1443 VSNLEKKQKKFDQLLAEEKNI 1463
Score = 31.2 bits (69), Expect = 3.9
Identities = 54/305 (17%), Positives = 115/305 (37%), Gaps = 37/305 (12%)
Frame = +2
Query: 32 KDMRDQTMEYEETKRLIEEDADREILDTKIKYERR---------LREERESNARLKGETG 184
K RD E E K +E+ D +++ +R L EE S+ + +
Sbjct: 1139 KQKRDLGEELEALKTELEDTLDTTATQQELRAKREQEVTVLKKALDEETRSH---EAQVQ 1195
Query: 185 IMKKKFASLXXXXXXXXXXXXXFQTETQKLENVIRNLEKDKVGLKKEI----QERDETIQ 352
M++K + F+ L+ + LEK+ L E+ Q + E
Sbjct: 1196 EMRQKHTQVVEELTEQLEQ---FKRAKANLDKTKQTLEKENADLAGELRVLGQAKQEVEH 1252
Query: 353 DKEK---RIYDLKKKNQELDKFKFVLDYKIKELKKQIE--------------preLEIQS 481
K+K ++ +L+ K + ++ + L+ K+ +L+ ++E E+ S
Sbjct: 1253 KKKKLEVQLQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLSEAEGKAIKLAKEVAS 1312
Query: 482 AKEQIQEMESELERFSKHNSQLSLNIXXXXXXXXXXXXXXXXXRQATRDVEAQVRRFKTD 661
Q+Q+ + L+ ++ +S + +A +++E +
Sbjct: 1313 LGSQLQDTQELLQEETRQKLNVSTKLRQLEDERNSLQEQLDEEMEAKQNLERHISTLNIQ 1372
Query: 662 LYNCVSYIQDPKGLKDSIVALYKKHIQEDVTS-------EASVDADIQKEFTRQREHLER 820
L + +QD +S+ KK Q+++ S +A+ ++K R ++ L+
Sbjct: 1373 LSDSKKKLQDFASTVESLEE-GKKRFQKEIESLTQQYEEKAAAYDKLEKTKNRLQQELDD 1431
Query: 821 SVASL 835
V L
Sbjct: 1432 LVVDL 1436
>sp|Q8VDD5|MYH9_MOUSE Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy
chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin
heavy chain, type A) (Nonmuscle myosin heavy chain-A)
(NMMHC-A)
Length = 1960
Score = 55.8 bits (133), Expect = 1e-07
Identities = 70/312 (22%), Positives = 129/312 (41%), Gaps = 33/312 (10%)
Frame = +2
Query: 5 KSTILENLNKDMRDQTMEYEETKRLIEEDADREILDTKIK-YERRLREERESNARLKGET 181
K LE + D+ + E EE + ++ A+++ + I+ E +L EE + +L+ E
Sbjct: 909 KKQELEEICHDLEARVEEEEERCQYLQ--AEKKKMQQNIQELEEQLEEEESARQKLQLEK 966
Query: 182 GIMKKKFASLXXXXXXXXXXXXXFQTETQKLE--------NVIRNLEKDKVGLKKEIQER 337
+ K L E + LE N++ EK K L K +
Sbjct: 967 VTTEAKLKKLEEDQIIMEDQNCKLAKEKKLLEDRVAEFTTNLMEEEEKSK-SLAKLKNKH 1025
Query: 338 DETIQDKEKRIYDLKKKNQELDKFKFVLD--------------YKIKELKKQIEpreLEI 475
+ I D E+R+ +K+ QEL+K + L+ +I ELK Q+ +E E+
Sbjct: 1026 EAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEEL 1085
Query: 476 QSAKEQIQEMESELERFSKHNSQLSLNIXXXXXXXXXXXXXXXXXRQATRDVEAQVRRFK 655
Q+A +++E ++ K +L I + RD+ ++ K
Sbjct: 1086 QAALARVEEEAAQKNMALKKIRELETQISELQEDLESERASRNKAEKQKRDLGEELEALK 1145
Query: 656 TDLYNCVSYI---QDPKGLKDSIVALYKKHIQEDV-TSEASVDADIQK------EFTRQR 805
T+L + + Q+ + ++ V++ KK ++++ T EA + QK E Q
Sbjct: 1146 TELEDTLDSTAAQQELRSKREQEVSILKKTLEDEAKTHEAQIQEMRQKHSQAVEELADQL 1205
Query: 806 EHLERSVASLRK 841
E +R A+L K
Sbjct: 1206 EQTKRVKATLEK 1217
Score = 45.1 bits (105), Expect = 3e-04
Identities = 50/289 (17%), Positives = 122/289 (42%), Gaps = 38/289 (13%)
Frame = +2
Query: 17 LENLNKDMRDQTMEY---EETKRLIEEDADREILDT-------------KIKYERRLREE 148
LE L++ + ++ Y E+TK ++++ D ++D + K+++ L EE
Sbjct: 1394 LEGLSQRLEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSVSNLEKKQKKFDQLLAEE 1453
Query: 149 R-------ESNARLKGETGIMKKKFASLXXXXXXXXXXXXXFQTETQKLENVIRNLEKDK 307
+ E R + E + K SL + ++ + +L K
Sbjct: 1454 KTISAKYAEERDRAEAEAREKETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSK 1513
Query: 308 VGLKKEIQERDETIQDKEKRIYDLKKKNQEL-DKFKFVLDYKIK----------ELKKQI 454
+ K + E +++ + E+++ ++K + +EL D+ + D K++ + ++ +
Sbjct: 1514 DDVGKSVHELEKSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDL 1573
Query: 455 EpreLEIQSAKEQ----IQEMESELERFSKHNSQLSLNIXXXXXXXXXXXXXXXXXRQAT 622
+ R+ + + K+Q ++EME+ELE K S +
Sbjct: 1574 QGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAMAARKKLEMDLKDLEAHIDTANKNR 1633
Query: 623 RDVEAQVRRFKTDLYNCVSYIQDPKGLKDSIVALYKKHIQEDVTSEASV 769
+ Q+R+ + + +C+ + D + ++ I+A K++ ++ + EA +
Sbjct: 1634 EEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEM 1682
Score = 41.2 bits (95), Expect = 0.004
Identities = 23/95 (24%), Positives = 51/95 (53%)
Frame = +2
Query: 269 KLENVIRNLEKDKVGLKKEIQERDETIQDKEKRIYDLKKKNQELDKFKFVLDYKIKELKK 448
++E + L +K+ L++++Q E + E+ L K QEL++ L+ +++E ++
Sbjct: 870 EMETMQSQLMAEKLQLQEQLQAETELCAEAEELRARLTAKKQELEEICHDLEARVEEEEE 929
Query: 449 QIEpreLEIQSAKEQIQEMESELERFSKHNSQLSL 553
+ + + E + ++ IQE+E +LE +L L
Sbjct: 930 RCQYLQAEKKKMQQNIQELEEQLEEEESARQKLQL 964
Score = 41.2 bits (95), Expect = 0.004
Identities = 25/127 (19%), Positives = 60/127 (47%)
Frame = +2
Query: 140 REERESNARLKGETGIMKKKFASLXXXXXXXXXXXXXFQTETQKLENVIRNLEKDKVGLK 319
R+ +E A+L+ +K K+ + + + +LE + N K++
Sbjct: 1785 RQNKELKAKLQEMESAVKSKYKA----------SIAALEAKIAQLEEQLDNETKERQAAS 1834
Query: 320 KEIQERDETIQDKEKRIYDLKKKNQELDKFKFVLDYKIKELKKQIEpreLEIQSAKEQIQ 499
K+++ ++ ++D ++ D ++ ++ ++K+LK+Q+E E E Q A +
Sbjct: 1835 KQVRRTEKKLKDVLLQVEDERRNAEQFKDQADKASTRLKQLKRQLEEAEEEAQRANASRR 1894
Query: 500 EMESELE 520
+++ ELE
Sbjct: 1895 KLQRELE 1901
Score = 38.9 bits (89), Expect = 0.019
Identities = 36/193 (18%), Positives = 77/193 (39%), Gaps = 28/193 (14%)
Frame = +2
Query: 38 MRDQTMEYEETKRLIEEDADR---EILDTKIKYERRLREERESNARL----------KGE 178
++++ E KR +++ D EI ++ K L E+R AR+ +G
Sbjct: 1685 LQEELAAAERAKRQAQQERDELADEIANSSGKGALALEEKRRLEARIALLEEELEEEQGN 1744
Query: 179 TGIMKKKFASLXXXXXXXXXXXXXFQTETQKLENVIRNLEKDKVGLKKEIQERDETIQDK 358
T ++ + ++ QK EN + LE+ LK ++QE + ++ K
Sbjct: 1745 TELINDRLKKANLQIDQINTDLNLERSHAQKNENARQQLERQNKELKAKLQEMESAVKSK 1804
Query: 359 ---------------EKRIYDLKKKNQELDKFKFVLDYKIKELKKQIEpreLEIQSAKEQ 493
E+++ + K+ Q K + K+K++ Q+E + K+Q
Sbjct: 1805 YKASIAALEAKIAQLEEQLDNETKERQAASKQVRRTEKKLKDVLLQVEDERRNAEQFKDQ 1864
Query: 494 IQEMESELERFSK 532
+ + L++ +
Sbjct: 1865 ADKASTRLKQLKR 1877
>sp|Q62812|MYH9_RAT Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy
chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin
heavy chain, type A) (Nonmuscle myosin heavy chain-A)
(NMMHC-A)
Length = 1961
Score = 55.1 bits (131), Expect = 3e-07
Identities = 66/293 (22%), Positives = 125/293 (42%), Gaps = 18/293 (6%)
Frame = +2
Query: 17 LENLNKDMRDQTMEYEETKRLIEEDADREILDT-KIKYERRLREERESNARLKGETGIMK 193
L+ K M+ E EE +L EE++ R+ L K+ E +L++ E IM+
Sbjct: 934 LQAEKKKMQQNIQELEE--QLEEEESARQKLQLEKVTTEAKLKKLEEDQI-------IME 984
Query: 194 KKFASLXXXXXXXXXXXXXFQTETQKLENVIRNLEKDKVGLKKEIQERDETIQDKEKRIY 373
+ L F T+ + E ++L K K + I + +E ++ +EK+
Sbjct: 985 DQNCKLAKEKKLLEDRVAEFTTDLMEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQ 1044
Query: 374 DLKKKNQELDKFKF-------VLDYKIKELKKQIEpreLEIQSAKEQIQEMESELERFSK 532
+L+K ++L+ L +I ELK Q+ +E E+Q+A +++E ++ K
Sbjct: 1045 ELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALK 1104
Query: 533 HNSQLSLNIXXXXXXXXXXXXXXXXXRQATRDVEAQVRRFKTDLYNCVSYI---QDPKGL 703
+L I + RD+ ++ KT+L + + Q+ +
Sbjct: 1105 KIRELETQISELQEDLESERACRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSK 1164
Query: 704 KDSIVALYKKHIQEDV-TSEASVDADIQK------EFTRQREHLERSVASLRK 841
++ V++ KK ++++ T EA + QK E Q E +R A+L K
Sbjct: 1165 REQEVSILKKTLEDEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKATLEK 1217
Score = 43.9 bits (102), Expect = 6e-04
Identities = 50/289 (17%), Positives = 122/289 (42%), Gaps = 38/289 (13%)
Frame = +2
Query: 17 LENLNKDMRDQTMEY---EETKRLIEEDADREILDT-------------KIKYERRLREE 148
LE L++ + ++ Y E+TK ++++ D ++D + K+++ L EE
Sbjct: 1395 LEGLSQRLEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSVSNLEKKQKKFDQLLAEE 1454
Query: 149 R-------ESNARLKGETGIMKKKFASLXXXXXXXXXXXXXFQTETQKLENVIRNLEKDK 307
+ E R + E + K SL + ++ + +L K
Sbjct: 1455 KTISAKYAEERDRAEAEAREKETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSK 1514
Query: 308 VGLKKEIQERDETIQDKEKRIYDLKKKNQEL-DKFKFVLDYKIK----------ELKKQI 454
+ K + E +++ + E+++ ++K + +EL D+ + D K++ + ++ +
Sbjct: 1515 DDVGKSVHELEKSNRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDL 1574
Query: 455 EpreLEIQSAKEQ----IQEMESELERFSKHNSQLSLNIXXXXXXXXXXXXXXXXXRQAT 622
+ R+ + + K+Q ++EME+ELE K S +
Sbjct: 1575 QGRDEQSEEKKKQLVRQVREMEAELEDERKQRSIAMAARKKLEMDLKDLEAHIDTANKNR 1634
Query: 623 RDVEAQVRRFKTDLYNCVSYIQDPKGLKDSIVALYKKHIQEDVTSEASV 769
+ Q+R+ + + +C+ + D + ++ I+A K++ ++ + EA +
Sbjct: 1635 EEAIKQLRKLQAQMKDCMRDVDDTRASREEILAQAKENEKKLKSMEAEM 1683
Score = 42.0 bits (97), Expect = 0.002
Identities = 23/95 (24%), Positives = 52/95 (54%)
Frame = +2
Query: 269 KLENVIRNLEKDKVGLKKEIQERDETIQDKEKRIYDLKKKNQELDKFKFVLDYKIKELKK 448
++E + L +K+ L++++Q + E + E+ L K QEL++ L+ +++E ++
Sbjct: 870 EMETMQSQLMAEKLQLQEQLQAKTELCAEAEELRARLTAKKQELEEICHDLEARVEEEEE 929
Query: 449 QIEpreLEIQSAKEQIQEMESELERFSKHNSQLSL 553
+ + + E + ++ IQE+E +LE +L L
Sbjct: 930 RCQYLQAEKKKMQQNIQELEEQLEEEESARQKLQL 964
Score = 41.2 bits (95), Expect = 0.004
Identities = 25/127 (19%), Positives = 60/127 (47%)
Frame = +2
Query: 140 REERESNARLKGETGIMKKKFASLXXXXXXXXXXXXXFQTETQKLENVIRNLEKDKVGLK 319
R+ +E A+L+ +K K+ + + + +LE + N K++
Sbjct: 1786 RQNKELKAKLQEMESAVKSKYKA----------SIAALEAKIAQLEEQLDNETKERQAAS 1835
Query: 320 KEIQERDETIQDKEKRIYDLKKKNQELDKFKFVLDYKIKELKKQIEpreLEIQSAKEQIQ 499
K+++ ++ ++D ++ D ++ ++ ++K+LK+Q+E E E Q A +
Sbjct: 1836 KQVRRAEKKLKDVLLQVEDERRNAEQFKDQADKASTRLKQLKRQLEEAEEEAQRANASRR 1895
Query: 500 EMESELE 520
+++ ELE
Sbjct: 1896 KLQRELE 1902
Score = 36.2 bits (82), Expect = 0.12
Identities = 35/193 (18%), Positives = 76/193 (39%), Gaps = 28/193 (14%)
Frame = +2
Query: 38 MRDQTMEYEETKRLIEEDADR---EILDTKIKYERRLREERESNARL----------KGE 178
++++ E KR +++ D EI ++ K L E+R A + +G
Sbjct: 1686 LQEELAAAERAKRQAQQERDELADEIANSSGKGALALEEKRRLEALIALLEEELEEEQGN 1745
Query: 179 TGIMKKKFASLXXXXXXXXXXXXXFQTETQKLENVIRNLEKDKVGLKKEIQERDETIQDK 358
T ++ + ++ QK EN + LE+ LK ++QE + ++ K
Sbjct: 1746 TELINDRLKKANLQIDQINTDLNLERSHAQKNENARQQLERQNKELKAKLQEMESAVKSK 1805
Query: 359 ---------------EKRIYDLKKKNQELDKFKFVLDYKIKELKKQIEpreLEIQSAKEQ 493
E+++ + K+ Q K + K+K++ Q+E + K+Q
Sbjct: 1806 YKASIAALEAKIAQLEEQLDNETKERQAASKQVRRAEKKLKDVLLQVEDERRNAEQFKDQ 1865
Query: 494 IQEMESELERFSK 532
+ + L++ +
Sbjct: 1866 ADKASTRLKQLKR 1878
>sp|P35579|MYH9_HUMAN Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy
chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin
heavy chain, type A) (Nonmuscle myosin heavy chain-A)
(NMMHC-A)
Length = 1960
Score = 54.7 bits (130), Expect = 3e-07
Identities = 71/312 (22%), Positives = 127/312 (40%), Gaps = 33/312 (10%)
Frame = +2
Query: 5 KSTILENLNKDMRDQTMEYEETKRLIEEDADREILDTKIK-YERRLREERESNARLKGET 181
K LE + D+ + E EE + ++ A+++ + I+ E +L EE + +L+ E
Sbjct: 909 KKQELEEICHDLEARVEEEEERCQHLQ--AEKKKMQQNIQELEEQLEEEESARQKLQLEK 966
Query: 182 GIMKKKFASLXXXXXXXXXXXXXFQTETQKLE--------NVIRNLEKDKVGLKKEIQER 337
+ K L E + LE N+ EK K L K +
Sbjct: 967 VTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSK-SLAKLKNKH 1025
Query: 338 DETIQDKEKRIYDLKKKNQELDKFKFVLD--------------YKIKELKKQIEpreLEI 475
+ I D E+R+ +K+ QEL+K + L+ +I ELK Q+ +E E+
Sbjct: 1026 EAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEEL 1085
Query: 476 QSAKEQIQEMESELERFSKHNSQLSLNIXXXXXXXXXXXXXXXXXRQATRDVEAQVRRFK 655
Q+A +++E ++ K +L I + RD+ ++ K
Sbjct: 1086 QAALARVEEEAAQKNMALKKIRELESQISELQEDLESERASRNKAEKQKRDLGEELEALK 1145
Query: 656 TDLYNCVSYI---QDPKGLKDSIVALYKKHIQEDV-TSEASVDADIQK------EFTRQR 805
T+L + + Q+ + ++ V + KK ++E+ T EA + QK E Q
Sbjct: 1146 TELEDTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQL 1205
Query: 806 EHLERSVASLRK 841
E +R A+L K
Sbjct: 1206 EQTKRVKANLEK 1217
Score = 42.0 bits (97), Expect = 0.002
Identities = 52/294 (17%), Positives = 118/294 (40%), Gaps = 43/294 (14%)
Frame = +2
Query: 17 LENLNKDMRDQTMEY---EETKRLIEEDADREILDTKIKYERR----LREERESNARLKG 175
LE L++ ++ Y E+TK ++++ D ++D + ++R+ L ++++ +L
Sbjct: 1394 LEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVD--LDHQRQSACNLEKKQKKFDQLLA 1451
Query: 176 ETGIMKKKFASLXXXXXXXXXXXXXFQTETQKLENVIRNLEKDKVGLKKEIQERDETIQD 355
E + K+A +T+ L + + K L++ ++ ++D
Sbjct: 1452 EEKTISAKYAEERDRAEAEAREK---ETKALSLARALEEAMEQKAELERLNKQFRTEMED 1508
Query: 356 KEKRIYDLKKKNQELDKFKFVLDYKIKELKKQIEpreLEIQSAKE--------------- 490
D+ K EL+K K L+ +++E+K Q+E E E+Q+ ++
Sbjct: 1509 LMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQ 1568
Query: 491 ---------------------QIQEMESELERFSKHNSQLSLNIXXXXXXXXXXXXXXXX 607
Q++EME+ELE K S
Sbjct: 1569 FERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDS 1628
Query: 608 XRQATRDVEAQVRRFKTDLYNCVSYIQDPKGLKDSIVALYKKHIQEDVTSEASV 769
+ + Q+R+ + + +C+ + D + ++ I+A K++ ++ + EA +
Sbjct: 1629 ANKNRDEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEM 1682
Score = 41.6 bits (96), Expect = 0.003
Identities = 23/95 (24%), Positives = 51/95 (53%)
Frame = +2
Query: 269 KLENVIRNLEKDKVGLKKEIQERDETIQDKEKRIYDLKKKNQELDKFKFVLDYKIKELKK 448
++E + L +K+ L++++Q E + E+ L K QEL++ L+ +++E ++
Sbjct: 870 EMETLQSQLMAEKLQLQEQLQAETELCAEAEELRARLTAKKQELEEICHDLEARVEEEEE 929
Query: 449 QIEpreLEIQSAKEQIQEMESELERFSKHNSQLSL 553
+ + + E + ++ IQE+E +LE +L L
Sbjct: 930 RCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQL 964
Score = 40.0 bits (92), Expect = 0.008
Identities = 25/127 (19%), Positives = 60/127 (47%)
Frame = +2
Query: 140 REERESNARLKGETGIMKKKFASLXXXXXXXXXXXXXFQTETQKLENVIRNLEKDKVGLK 319
R+ +E +L+ G +K K+ + + + +LE + N K++
Sbjct: 1785 RQNKELKVKLQEMEGTVKSKYKA----------SITALEAKIAQLEEQLDNETKERQAAC 1834
Query: 320 KEIQERDETIQDKEKRIYDLKKKNQELDKFKFVLDYKIKELKKQIEpreLEIQSAKEQIQ 499
K+++ ++ ++D ++ D ++ ++ ++K+LK+Q+E E E Q A +
Sbjct: 1835 KQVRRTEKKLKDVLLQVDDERRNAEQYKDQADKASTRLKQLKRQLEEAEEEAQRANASRR 1894
Query: 500 EMESELE 520
+++ ELE
Sbjct: 1895 KLQRELE 1901
Score = 37.4 bits (85), Expect = 0.055
Identities = 36/193 (18%), Positives = 78/193 (40%), Gaps = 28/193 (14%)
Frame = +2
Query: 38 MRDQTMEYEETKRLIEEDADR---EILDTKIKYERRLREERESNARL----------KGE 178
++++ E KR +++ D EI ++ K L E+R AR+ +G
Sbjct: 1685 LQEELAAAERAKRQAQQERDELADEIANSSGKGALALEEKRRLEARIAQLEEELEEEQGN 1744
Query: 179 TGIMKKKFASLXXXXXXXXXXXXXFQTETQKLENVIRNLEKDKVGLKKEIQERDETIQDK 358
T ++ + ++ QK EN + LE+ LK ++QE + T++ K
Sbjct: 1745 TELINDRLKKANLQIDQINTDLNLERSHAQKNENARQQLERQNKELKVKLQEMEGTVKSK 1804
Query: 359 ---------------EKRIYDLKKKNQELDKFKFVLDYKIKELKKQIEpreLEIQSAKEQ 493
E+++ + K+ Q K + K+K++ Q++ + K+Q
Sbjct: 1805 YKASITALEAKIAQLEEQLDNETKERQAACKQVRRTEKKLKDVLLQVDDERRNAEQYKDQ 1864
Query: 494 IQEMESELERFSK 532
+ + L++ +
Sbjct: 1865 ADKASTRLKQLKR 1877
>sp|Q12267|SMC4_YEAST Structural maintenance of chromosome 4
Length = 1418
Score = 54.3 bits (129), Expect = 4e-07
Identities = 46/199 (23%), Positives = 90/199 (45%), Gaps = 18/199 (9%)
Frame = +2
Query: 17 LENLNKDMRDQTMEYEETKRLIEEDADREILDTKIKYERRLREERESNARLKGETGIMKK 196
+ + NKD+ D+ M+++E+ + ++E IK +R+ ++R S+ K +T ++++
Sbjct: 414 ISSSNKDLEDEKMKFQESLKKVDE----------IKAQRKEIKDRISSCSSKEKTLVLER 463
Query: 197 KFASLXXXXXXXXXXXXXFQTETQKLENVIRNLEKDKVGLKKEIQERDETIQD------- 355
+ + T+ L + + EK K I E + +++
Sbjct: 464 R---------ELEGTRVSLEERTKNLVSKMEKAEKTLKSTKHSISEAENMLEELRGQQTE 514
Query: 356 KEKRIYDL----KKKNQELDKFKFVLDYKIKEL-------KKQIEpreLEIQSAKEQIQE 502
E I DL +K+ LD K L K K + +K++EP +L++Q + QIQ
Sbjct: 515 HETEIKDLTQLLEKERSILDDIKLSLKDKTKNISAEIIRHEKELEPWDLQLQEKESQIQL 574
Query: 503 MESELERFSKHNSQLSLNI 559
ESEL + ++L N+
Sbjct: 575 AESELSLLEETQAKLKKNV 593
Score = 35.0 bits (79), Expect = 0.27
Identities = 39/189 (20%), Positives = 85/189 (44%), Gaps = 9/189 (4%)
Frame = +2
Query: 5 KSTILENLNKDMRDQTMEYEETKRLIE--EDADREILDTK---IKYERRLREER----ES 157
K+ +LE + ++E E TK L+ E A++ + TK + E L E R E
Sbjct: 457 KTLVLERRELEGTRVSLE-ERTKNLVSKMEKAEKTLKSTKHSISEAENMLEELRGQQTEH 515
Query: 158 NARLKGETGIMKKKFASLXXXXXXXXXXXXXFQTETQKLENVIRNLEKDKVGLKKEIQER 337
+K T +++K+ + L L++ +N+ + + +KE++
Sbjct: 516 ETEIKDLTQLLEKERSILDDIKL--------------SLKDKTKNISAEIIRHEKELEPW 561
Query: 338 DETIQDKEKRIYDLKKKNQELDKFKFVLDYKIKELKKQIEpreLEIQSAKEQIQEMESEL 517
D +Q+KE +I + + L++ + L ++ L+++I ++ Q ++ I +++ +L
Sbjct: 562 DLQLQEKESQIQLAESELSLLEETQAKLKKNVETLEEKILAKKTHKQELQDLILDLKKKL 621
Query: 518 ERFSKHNSQ 544
SQ
Sbjct: 622 NSLKDERSQ 630
Score = 33.5 bits (75), Expect = 0.79
Identities = 40/168 (23%), Positives = 68/168 (40%), Gaps = 2/168 (1%)
Frame = +2
Query: 20 ENLNKDMRDQTMEYE-ETKRLIEE-DADREILDTKIKYERRLREERESNARLKGETGIMK 193
EN+ +++R Q E+E E K L + + +R ILD + LK +T +
Sbjct: 502 ENMLEELRGQQTEHETEIKDLTQLLEKERSILD-------------DIKLSLKDKTKNIS 548
Query: 194 KKFASLXXXXXXXXXXXXXFQTETQKLENVIRNLEKDKVGLKKEIQERDETIQDKEKRIY 373
+ +++ Q E+ + LE+ + LKK ++ +E I K
Sbjct: 549 AEIIRHEKELEPWDLQLQEKESQIQLAESELSLLEETQAKLKKNVETLEEKILAK----- 603
Query: 374 DLKKKNQELDKFKFVLDYKIKELKKQIEpreLEIQSAKEQIQEMESEL 517
K QEL L K+ LK + E SA +++EM+ L
Sbjct: 604 --KTHKQELQDLILDLKKKLNSLKDERSQGEKNFTSAHLKLKEMQKVL 649
>sp|P14105|MYH9_CHICK Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy
chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin
heavy chain, type A) (Nonmuscle myosin heavy chain-A)
(NMMHC-A)
Length = 1959
Score = 53.5 bits (127), Expect = 7e-07
Identities = 70/312 (22%), Positives = 127/312 (40%), Gaps = 33/312 (10%)
Frame = +2
Query: 5 KSTILENLNKDMRDQTMEYEETKRLIEEDADREILDTKIK-YERRLREERESNARLKGET 181
K LE + D+ + E EE + ++ A+++ + I+ E +L EE + +L+ E
Sbjct: 909 KKQELEEICHDLEARVEEEEERCQHLQ--AEKKKMQQNIQELEEQLEEEESARQKLQLEK 966
Query: 182 GIMKKKFASLXXXXXXXXXXXXXFQTETQKLE--------NVIRNLEKDKVGLKKEIQER 337
+ K L E + LE N+ EK K L K +
Sbjct: 967 VTTEAKLKKLEEDVIVLEDQNLKLAKEKKLLEDRMSEFTTNLTEEEEKSK-SLAKLKNKH 1025
Query: 338 DETIQDKEKRIYDLKKKNQELDKFKFVLD--------------YKIKELKKQIEpreLEI 475
+ I D E+R+ +K+ QEL+K + L+ +I ELK Q+ +E E+
Sbjct: 1026 EAMITDLEERLRREEKQRQELEKTRRKLEGDSSDLHDQIAELQAQIAELKIQLSKKEEEL 1085
Query: 476 QSAKEQIQEMESELERFSKHNSQLSLNIXXXXXXXXXXXXXXXXXRQATRDVEAQVRRFK 655
Q+A +++E ++ K +L I + RD+ ++ K
Sbjct: 1086 QAALARVEEEAAQKNMALKKIRELESQITELQEDLESERASRNKAEKQKRDLGEELEALK 1145
Query: 656 TDLYNCVSYI---QDPKGLKDSIVALYKKHIQEDV-TSEASVDADIQK------EFTRQR 805
T+L + + Q+ + ++ V + KK ++++ T EA + QK E Q
Sbjct: 1146 TELEDTLDSTAAQQELRSKREQEVTVLKKTLEDEAKTHEAQIQEMRQKHSQAIEELAEQL 1205
Query: 806 EHLERSVASLRK 841
E +R A+L K
Sbjct: 1206 EQTKRVKANLEK 1217
Score = 42.7 bits (99), Expect = 0.001
Identities = 62/304 (20%), Positives = 129/304 (42%), Gaps = 25/304 (8%)
Frame = +2
Query: 17 LENLNKDMRDQTMEYEETKRLIEEDADREILDTKIKYERRLREERESNARLKGETGIMKK 196
++ NK+ RD+ +++ + +D RE+ DT+ E L + +E+ +LK M+
Sbjct: 1626 IDTANKN-RDEAIKHVRKLQAQMKDYMRELEDTRTSREEILAQAKENEKKLKS----MEA 1680
Query: 197 KFASLXXXXXXXXXXXXXFQTETQKLENVIRNLE-------KDKVGLKKEIQERDETIQD 355
+ L Q E +L + I N ++K L+ I + +E +++
Sbjct: 1681 EMIQLQEELAAAERAKRQAQQERDELADEIANSSGKGALAMEEKRRLEARIAQLEEELEE 1740
Query: 356 KE---KRIYD-LKKKNQELDKFKFVLDYKIKELKKQIEPR---ELEIQSAKEQIQEMESE 514
++ + I D LKK N ++D+ L+ + +K R E + + K ++QEMES
Sbjct: 1741 EQGNTEIINDRLKKANLQIDQMNADLNAERSNAQKNENARQQMERQNKELKLKLQEMESA 1800
Query: 515 LERFSKHNSQLSLNIXXXXXXXXXXXXXXXXXRQATRDVEAQVRRFKTDLYNCVSYIQDP 694
++ SK+ + ++ + A++ V ++ K L ++
Sbjct: 1801 VK--SKYKATITALEAKIVQLEEQLDMETKERQAASKQVRRAEKKLKDILLQVDDERRNA 1858
Query: 695 KGLKDSI------VALYKKHIQ--EDVTSEASVDADIQKEF---TRQREHLERSVASLRK 841
+ KD + K+ ++ E+ A+V +Q+E T + + R V+SL+
Sbjct: 1859 EQFKDQADKANMRLKQLKRQLEEAEEEAQRANVRRKLQRELDDATETADAMNREVSSLKS 1918
Query: 842 NYRK 853
R+
Sbjct: 1919 KLRR 1922
Score = 40.4 bits (93), Expect = 0.006
Identities = 23/100 (23%), Positives = 51/100 (51%)
Frame = +2
Query: 254 QTETQKLENVIRNLEKDKVGLKKEIQERDETIQDKEKRIYDLKKKNQELDKFKFVLDYKI 433
+ ++E L +K+ L++++Q E + E+ L K QEL++ L+ ++
Sbjct: 865 ENRLSEMETFQAQLMAEKMQLQEQLQAEAELCAEAEEIRARLTAKKQELEEICHDLEARV 924
Query: 434 KELKKQIEpreLEIQSAKEQIQEMESELERFSKHNSQLSL 553
+E +++ + + E + ++ IQE+E +LE +L L
Sbjct: 925 EEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQL 964
Score = 38.5 bits (88), Expect = 0.025
Identities = 37/177 (20%), Positives = 78/177 (44%), Gaps = 14/177 (7%)
Frame = +2
Query: 20 ENLNKDMRDQTMEYEE----------TKRLIEEDADREILDTKIKYERR----LREERES 157
+ L KD+ T YEE TK ++++ D +D + ++R+ L ++++
Sbjct: 1388 KKLQKDLESLTQRYEEKIAAYDKLEKTKTRLQQELDDIAVD--LDHQRQTVSNLEKKQKK 1445
Query: 158 NARLKGETGIMKKKFASLXXXXXXXXXXXXXFQTETQKLENVIRNLEKDKVGLKKEIQER 337
+L E + K+A +T+ L + + K L++ ++
Sbjct: 1446 FDQLLAEEKNISAKYAEERDRAEAEAREK---ETKALSLARALEEAIEQKAELERVNKQF 1502
Query: 338 DETIQDKEKRIYDLKKKNQELDKFKFVLDYKIKELKKQIEpreLEIQSAKEQIQEME 508
++D D+ K EL+K K L+ +++E+K Q+E E E+Q+ ++ +E
Sbjct: 1503 RTEMEDLMSSKDDVGKSVHELEKAKRALEQQVEEMKTQLEELEDELQATEDAKLRLE 1559
>sp|P93203|MFP1_LYCES MAR binding filament-like protein 1
Length = 697
Score = 53.5 bits (127), Expect = 7e-07
Identities = 71/319 (22%), Positives = 128/319 (40%), Gaps = 30/319 (9%)
Frame = +2
Query: 2 GKSTILENLNKDMRDQTMEYEETKRLIEEDA--------DREILDTKIKYERRLREERES 157
G L K + D T+E + K +EDA + E+L + + +R E E
Sbjct: 122 GSLYALARNEKAVSDATIESMKNKLKDKEDAFVSMKKQFESELLSEREDRNKLIRREGEE 181
Query: 158 NARLKGETGIMKKKFASLXXXXXXXXXXXXXFQTETQKLENVIRNLEKDKVGLKKEIQER 337
L + K SL + E + L+N + N ++DK L++E++E+
Sbjct: 182 RQALVNQLKSAKTTVISLGQELQNEKKLAEDLKFEIKGLQNDLMNTKEDKKKLQEELKEK 241
Query: 338 DETIQDKEKRI----YDLKKKNQELDKFKFVLDYKIKEL----------KKQIEpreLEI 475
+ IQ E++I ++K K L L K E+ + Q+ EI
Sbjct: 242 LDLIQVLEEKITLLTTEIKDKEVSLRSNTSKLAEKESEVNSLSDMYQQSQDQLMNLTSEI 301
Query: 476 QSAKEQIQEMESELER--FSKHNSQLSLNIXXXXXXXXXXXXXXXXXRQATRDVEAQVRR 649
+ K++IQ+ E ELE S+ N + LN ++ ++ +
Sbjct: 302 KELKDEIQKRERELELKCVSEDNLNVQLN---------SLLLERDESKKELHAIQKEYSE 352
Query: 650 FKTDLYNCVSYIQDPKGLKDSIVALYKKHIQE------DVTSEASVDADIQKEFTRQREH 811
FK++ D K D+ + +K + + SEAS + + + TR++E+
Sbjct: 353 FKSN--------SDEKVASDATLGEQEKRLHQLEEQLGTALSEASKNEVLIADLTREKEN 404
Query: 812 LERSVASLRKNYRKIQKFI 868
L R V + N K+++ I
Sbjct: 405 LRRMVDAELDNVNKLKQEI 423
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 73,872,501
Number of Sequences: 369166
Number of extensions: 1255285
Number of successful extensions: 8322
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 6383
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 7885
length of database: 68,354,980
effective HSP length: 110
effective length of database: 48,034,130
effective search space used: 8646143400
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)