Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_016_E10
(631 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q01484|ANK2_HUMAN Ankyrin-2 (Brain ankyrin) (Ankyrin B) ... 46 7e-05
sp|Q9H9B1|EHMT1_HUMAN Histone-lysine N-methyltransferase, H... 46 9e-05
sp|Q9ULJ7|YB23_HUMAN Hypothetical protein KIAA1223 45 1e-04
sp|Q00420|GABP2_MOUSE GA binding protein beta chain (GABP-b... 44 3e-04
sp|Q06547|GABP2_HUMAN GA binding protein beta chain (GABP-b... 44 3e-04
sp|Q06527|ANKH_CHRVI Ankyrin homolog precursor 44 3e-04
sp|Q8WWH4|ASZ1_HUMAN Ankyrin repeat, SAM and basic leucine ... 44 3e-04
sp|Q8WMX6|ASZ1_PANTR Ankyrin repeat, SAM and basic leucine ... 44 3e-04
sp|Q12955|ANK3_HUMAN Ankyrin-3 (ANK-3) (Ankyrin G) 44 3e-04
sp|Q9D2J7|ANKR5_MOUSE Ankyrin repeat domain protein 5 44 4e-04
>sp|Q01484|ANK2_HUMAN Ankyrin-2 (Brain ankyrin) (Ankyrin B) (Ankyrin, nonerythroid)
Length = 3924
Score = 46.2 bits (108), Expect = 7e-05
Identities = 24/70 (34%), Positives = 39/70 (55%)
Frame = +3
Query: 33 ASIHDKSDNDNPWDSEADFSPLMFATYHGHSKLVEGLIDSGAKVNKGDRKGWTCLHGAAH 212
A I K D ++ ++PL+ A ++G+ K+V L+ GA VN + G+T LH AA
Sbjct: 711 ADILTKHGADQDAHTKLGYTPLIVACHYGNVKMVNFLLKQGANVNAKTKNGYTPLHQAAQ 770
Query: 213 RCHEKIVKLL 242
+ H I+ +L
Sbjct: 771 QGHTHIINVL 780
Score = 40.4 bits (93), Expect = 0.004
Identities = 24/77 (31%), Positives = 43/77 (55%)
Frame = +3
Query: 12 SLLIECGASIHDKSDNDNPWDSEADFSPLMFATYHGHSKLVEGLIDSGAKVNKGDRKGWT 191
+LL+ GA++ + N +PL A+ G++ +V+ L+D G +++ R G T
Sbjct: 250 TLLLNRGAAVDFTARNG--------ITPLHVASKRGNTNMVKLLLDRGGQIDAKTRDGLT 301
Query: 192 CLHGAAHRCHEKIVKLL 242
LH AA H+++V+LL
Sbjct: 302 PLHCAARSGHDQVVELL 318
Score = 36.2 bits (82), Expect = 0.071
Identities = 24/80 (30%), Positives = 41/80 (51%)
Frame = +3
Query: 3 KSLSLLIECGASIHDKSDNDNPWDSEADFSPLMFATYHGHSKLVEGLIDSGAKVNKGDRK 182
K + LL++ GASI + E+ +P+ A + GH +V L+ +GA + + +
Sbjct: 412 KVMELLVKYGASIQAIT--------ESGLTPIHVAAFMGHLNIVLLLLQNGASPDVTNIR 463
Query: 183 GWTCLHGAAHRCHEKIVKLL 242
G T LH AA ++V+ L
Sbjct: 464 GETALHMAARAGQVEVVRCL 483
Score = 35.8 bits (81), Expect = 0.093
Identities = 17/51 (33%), Positives = 27/51 (52%)
Frame = +3
Query: 90 SPLMFATYHGHSKLVEGLIDSGAKVNKGDRKGWTCLHGAAHRCHEKIVKLL 242
+PL A+ GH+ +V L+D GA ++ + G T LH AA + +L
Sbjct: 664 TPLHLASQEGHTDMVTLLLDKGANIHMSTKSGLTSLHLAAQEDKVNVADIL 714
Score = 35.4 bits (80), Expect = 0.12
Identities = 22/78 (28%), Positives = 40/78 (51%)
Frame = +3
Query: 9 LSLLIECGASIHDKSDNDNPWDSEADFSPLMFATYHGHSKLVEGLIDSGAKVNKGDRKGW 188
+ +L++ GA+I+ +S N F+PL A H +V+ L+++GA + G+
Sbjct: 113 VKVLVKEGANINAQSQNG--------FTPLYMAAQENHIDVVKYLLENGANQSTATEDGF 164
Query: 189 TCLHGAAHRCHEKIVKLL 242
T L A + H + V +L
Sbjct: 165 TPLAVALQQGHNQAVAIL 182
Score = 33.5 bits (75), Expect = 0.46
Identities = 25/78 (32%), Positives = 36/78 (46%)
Frame = +3
Query: 9 LSLLIECGASIHDKSDNDNPWDSEADFSPLMFATYHGHSKLVEGLIDSGAKVNKGDRKGW 188
+ LL+E GA + ++ N SPL A H + V+ L+ A V+
Sbjct: 315 VELLLERGAPLLARTKNG--------LSPLHMAAQGDHVECVKHLLQHKAPVDDVTLDYL 366
Query: 189 TCLHGAAHRCHEKIVKLL 242
T LH AAH H ++ KLL
Sbjct: 367 TALHVAAHCGHYRVTKLL 384
Score = 33.1 bits (74), Expect = 0.60
Identities = 18/49 (36%), Positives = 27/49 (55%)
Frame = +3
Query: 96 LMFATYHGHSKLVEGLIDSGAKVNKGDRKGWTCLHGAAHRCHEKIVKLL 242
L A GH LV+ L+ G+ V+ +KG T LH A+ ++VK+L
Sbjct: 68 LHLAAKEGHVGLVQELLGRGSSVDSATKKGNTALHIASLAGQAEVVKVL 116
Score = 33.1 bits (74), Expect = 0.60
Identities = 17/49 (34%), Positives = 28/49 (57%)
Frame = +3
Query: 96 LMFATYHGHSKLVEGLIDSGAKVNKGDRKGWTCLHGAAHRCHEKIVKLL 242
L A+ G +++V+ L+ GA +N + G+T L+ AA H +VK L
Sbjct: 101 LHIASLAGQAEVVKVLVKEGANINAQSQNGFTPLYMAAQENHIDVVKYL 149
Score = 33.1 bits (74), Expect = 0.60
Identities = 24/78 (30%), Positives = 38/78 (48%)
Frame = +3
Query: 9 LSLLIECGASIHDKSDNDNPWDSEADFSPLMFATYHGHSKLVEGLIDSGAKVNKGDRKGW 188
+ LL++ G I K+ + +PL A GH ++VE L++ GA + + G
Sbjct: 282 VKLLLDRGGQIDAKTRDG--------LTPLHCAARSGHDQVVELLLERGAPLLARTKNGL 333
Query: 189 TCLHGAAHRCHEKIVKLL 242
+ LH AA H + VK L
Sbjct: 334 SPLHMAAQGDHVECVKHL 351
Score = 33.1 bits (74), Expect = 0.60
Identities = 22/77 (28%), Positives = 38/77 (49%)
Frame = +3
Query: 12 SLLIECGASIHDKSDNDNPWDSEADFSPLMFATYHGHSKLVEGLIDSGAKVNKGDRKGWT 191
S+L+E GA+ + ++ F+PL A +G + + L+ A + + G T
Sbjct: 547 SVLLEAGAA--------HSLATKKGFTPLHVAAKYGSLDVAKLLLQRRAAADSAGKNGLT 598
Query: 192 CLHGAAHRCHEKIVKLL 242
LH AAH ++K+ LL
Sbjct: 599 PLHVAAHYDNQKVALLL 615
Score = 32.7 bits (73), Expect = 0.78
Identities = 19/65 (29%), Positives = 33/65 (50%)
Frame = +3
Query: 3 KSLSLLIECGASIHDKSDNDNPWDSEADFSPLMFATYHGHSKLVEGLIDSGAKVNKGDRK 182
K ++ L++ GA+++ K+ N ++PL A GH+ ++ L+ GAK N
Sbjct: 742 KMVNFLLKQGANVNAKTKNG--------YTPLHQAAQQGHTHIINVLLQHGAKPNATTAN 793
Query: 183 GWTCL 197
G T L
Sbjct: 794 GNTAL 798
Score = 29.3 bits (64), Expect = 8.7
Identities = 16/52 (30%), Positives = 27/52 (51%)
Frame = +3
Query: 87 FSPLMFATYHGHSKLVEGLIDSGAKVNKGDRKGWTCLHGAAHRCHEKIVKLL 242
++PL + G + L+++GA + +KG+T LH AA + KLL
Sbjct: 531 YTPLHISAREGQVDVASVLLEAGAAHSLATKKGFTPLHVAAKYGSLDVAKLL 582
>sp|Q9H9B1|EHMT1_HUMAN Histone-lysine N-methyltransferase, H3 lysine-9 specific 5 (Histone
H3-K9 methyltransferase 5) (H3-K9-HMTase 5) (Euchromatic
histone-lysine N-methyltransferase 1) (Eu-HMTase1)
(G9a-like protein 1) (GLP1)
Length = 1267
Score = 45.8 bits (107), Expect = 9e-05
Identities = 27/76 (35%), Positives = 44/76 (57%)
Frame = +3
Query: 15 LLIECGASIHDKSDNDNPWDSEADFSPLMFATYHGHSKLVEGLIDSGAKVNKGDRKGWTC 194
+L++ GA+I S++ +PLM A + H + V+ LI +GA V+ D +G TC
Sbjct: 760 MLVQAGANIDTCSEDQR--------TPLMEAAENNHLEAVKYLIKAGALVDPKDAEGSTC 811
Query: 195 LHGAAHRCHEKIVKLL 242
LH AA + H ++V+ L
Sbjct: 812 LHLAAKKGHYEVVQYL 827
Score = 32.3 bits (72), Expect = 1.0
Identities = 26/81 (32%), Positives = 41/81 (50%), Gaps = 1/81 (1%)
Frame = +3
Query: 3 KSLSLLIECGASIHDKSDNDNPWDSEADFSPLMFATYHGHSKLVEGLIDSGAK-VNKGDR 179
+++ LI+ GA + +P D+E + L A GH ++V+ L+ +G VN D
Sbjct: 789 EAVKYLIKAGALV-------DPKDAEGS-TCLHLAAKKGHYEVVQYLLSNGQMDVNCQDD 840
Query: 180 KGWTCLHGAAHRCHEKIVKLL 242
GWT + A H +VKLL
Sbjct: 841 GGWTPMIWATEYKHVDLVKLL 861
>sp|Q9ULJ7|YB23_HUMAN Hypothetical protein KIAA1223
Length = 768
Score = 45.4 bits (106), Expect = 1e-04
Identities = 30/80 (37%), Positives = 41/80 (51%)
Frame = +3
Query: 9 LSLLIECGASIHDKSDNDNPWDSEADFSPLMFATYHGHSKLVEGLIDSGAKVNKGDRKGW 188
+SLLI+ GA + D D D +PL+ A Y GH +V+ L++ GA V+ D G
Sbjct: 70 VSLLIDRGAEV-DHCDKDG-------MTPLLVAAYEGHVDVVDLLLEGGADVDHTDNNGR 121
Query: 189 TCLHGAAHRCHEKIVKLL*F 248
T L AA H +V L F
Sbjct: 122 TPLLAAASMGHASVVNTLLF 141
Score = 40.4 bits (93), Expect = 0.004
Identities = 29/80 (36%), Positives = 43/80 (53%), Gaps = 5/80 (6%)
Frame = +3
Query: 18 LIECGASIHDKSDNDNPWDSEADFSPLMFATYHGHSKLVEGLIDSGAKVNKGDRKGWTCL 197
L++ GA ++ K+DN+ + L+ A Y GH ++VE L+D GA+VN D G T L
Sbjct: 2 LLQHGAEVN-KADNEGR-------TALIAAAYMGHREIVEHLLDHGAEVNHEDVDGRTAL 53
Query: 198 HGA-----AHRCHEKIVKLL 242
A A + H +V LL
Sbjct: 54 SVAALCVPASKGHASVVSLL 73
Score = 39.7 bits (91), Expect = 0.006
Identities = 28/80 (35%), Positives = 40/80 (50%)
Frame = +3
Query: 3 KSLSLLIECGASIHDKSDNDNPWDSEADFSPLMFATYHGHSKLVEGLIDSGAKVNKGDRK 182
K + LLIE GA + D + N + L A GH +V+ L++ GA N D+
Sbjct: 365 KVVQLLIEHGAVV-DHTCNQGA-------TALCIAAQEGHIDVVQVLLEHGADPNHADQF 416
Query: 183 GWTCLHGAAHRCHEKIVKLL 242
G T + AA H +I+KLL
Sbjct: 417 GRTAMRVAAKNGHSQIIKLL 436
Score = 37.0 bits (84), Expect = 0.042
Identities = 22/74 (29%), Positives = 39/74 (52%)
Frame = +3
Query: 21 IECGASIHDKSDNDNPWDSEADFSPLMFATYHGHSKLVEGLIDSGAKVNKGDRKGWTCLH 200
+E ++ D+ ++N D +A ++PL A + GH + E LI+ GA+ N+ D G
Sbjct: 166 VEVVRTLLDRGLDENHRD-DAGWTPLHMAAFEGHRLICEALIEQGARTNEIDNDGRIPFI 224
Query: 201 GAAHRCHEKIVKLL 242
A+ H V++L
Sbjct: 225 LASQEGHYDCVQIL 238
Score = 35.0 bits (79), Expect = 0.16
Identities = 19/42 (45%), Positives = 26/42 (61%)
Frame = +3
Query: 117 GHSKLVEGLIDSGAKVNKGDRKGWTCLHGAAHRCHEKIVKLL 242
GH+ +V LID GA+V+ D+ G T L AA+ H +V LL
Sbjct: 65 GHASVVSLLIDRGAEVDHCDKDGMTPLLVAAYEGHVDVVDLL 106
Score = 35.0 bits (79), Expect = 0.16
Identities = 19/49 (38%), Positives = 25/49 (51%)
Frame = +3
Query: 96 LMFATYHGHSKLVEGLIDSGAKVNKGDRKGWTCLHGAAHRCHEKIVKLL 242
L A+ G+ ++V L+D G N D GWT LH AA H I + L
Sbjct: 157 LSIASAQGNVEVVRTLLDRGLDENHRDDAGWTPLHMAAFEGHRLICEAL 205
Score = 34.7 bits (78), Expect = 0.21
Identities = 25/78 (32%), Positives = 43/78 (55%)
Frame = +3
Query: 9 LSLLIECGASIHDKSDNDNPWDSEADFSPLMFATYHGHSKLVEGLIDSGAKVNKGDRKGW 188
+ LL+E GA + D +DN+ +PL+ A GH+ +V L+ GA V+ D +G
Sbjct: 103 VDLLLEGGADV-DHTDNNGR-------TPLLAAASMGHASVVNTLLFWGAAVDSIDSEGR 154
Query: 189 TCLHGAAHRCHEKIVKLL 242
T L A+ + + ++V+ L
Sbjct: 155 TVLSIASAQGNVEVVRTL 172
Score = 33.1 bits (74), Expect = 0.60
Identities = 18/49 (36%), Positives = 28/49 (57%)
Frame = +3
Query: 96 LMFATYHGHSKLVEGLIDSGAKVNKGDRKGWTCLHGAAHRCHEKIVKLL 242
L + + GH ++V+ LI A VN D + + L AA + H K+V+LL
Sbjct: 322 LHVSCWQGHMEMVQVLIAYHADVNAADNEKRSALQSAAWQGHVKVVQLL 370
>sp|Q00420|GABP2_MOUSE GA binding protein beta chain (GABP-beta-2 subunit) (GABP-2)
(GABP-beta-1 subunit) (GABPB-1)
Length = 383
Score = 44.3 bits (103), Expect = 3e-04
Identities = 22/56 (39%), Positives = 32/56 (57%)
Frame = +3
Query: 75 SEADFSPLMFATYHGHSKLVEGLIDSGAKVNKGDRKGWTCLHGAAHRCHEKIVKLL 242
++ D +PL A GH+ +VE L+ GA VN D T LH A H+++V+LL
Sbjct: 68 TKVDRTPLHMAASEGHANIVEVLLKHGADVNAKDMLKMTALHWATEHNHQEVVELL 123
Score = 30.8 bits (68), Expect = 3.0
Identities = 18/51 (35%), Positives = 25/51 (49%)
Frame = +3
Query: 90 SPLMFATYHGHSKLVEGLIDSGAKVNKGDRKGWTCLHGAAHRCHEKIVKLL 242
SPL A +GH E L+ +G + + T LH AA H IV++L
Sbjct: 40 SPLHLAAQYGHFSTTEVLLRAGVSRDARTKVDRTPLHMAASEGHANIVEVL 90
>sp|Q06547|GABP2_HUMAN GA binding protein beta chain (GABP-beta-2 subunit) (GABP-2)
(GABP-beta-1 subunit) (GABPB-1) (Transcription factor
E4TF1-53) (Transcription factor E4TF1-47) (Nuclear
respiratory factor 2)
Length = 395
Score = 44.3 bits (103), Expect = 3e-04
Identities = 22/56 (39%), Positives = 32/56 (57%)
Frame = +3
Query: 75 SEADFSPLMFATYHGHSKLVEGLIDSGAKVNKGDRKGWTCLHGAAHRCHEKIVKLL 242
++ D +PL A GH+ +VE L+ GA VN D T LH A H+++V+LL
Sbjct: 68 TKVDRTPLHMAASEGHASIVEVLLKHGADVNAKDMLKMTALHWATEHNHQEVVELL 123
Score = 30.8 bits (68), Expect = 3.0
Identities = 18/51 (35%), Positives = 25/51 (49%)
Frame = +3
Query: 90 SPLMFATYHGHSKLVEGLIDSGAKVNKGDRKGWTCLHGAAHRCHEKIVKLL 242
SPL A +GH E L+ +G + + T LH AA H IV++L
Sbjct: 40 SPLHLAAQYGHYSTTEVLLRAGVSRDARTKVDRTPLHMAASEGHASIVEVL 90
>sp|Q06527|ANKH_CHRVI Ankyrin homolog precursor
Length = 323
Score = 44.3 bits (103), Expect = 3e-04
Identities = 28/77 (36%), Positives = 43/77 (55%)
Frame = +3
Query: 12 SLLIECGASIHDKSDNDNPWDSEADFSPLMFATYHGHSKLVEGLIDSGAKVNKGDRKGWT 191
+LL+E GA +HD++ + WD+ LM A+ HG + +VE L+ GA DR+G T
Sbjct: 115 ALLLERGAHVHDRTRSG--WDA------LMIASRHGITDMVEQLLFKGADPKAADREGRT 166
Query: 192 CLHGAAHRCHEKIVKLL 242
L AA + ++ LL
Sbjct: 167 ALMQAASKGETGVLPLL 183
Score = 38.1 bits (87), Expect = 0.019
Identities = 20/49 (40%), Positives = 27/49 (55%)
Frame = +3
Query: 96 LMFATYHGHSKLVEGLIDSGAKVNKGDRKGWTCLHGAAHRCHEKIVKLL 242
L+ A HGH +VE L+ GA N+ DRKG T L A H +++ L
Sbjct: 234 LILAVGHGHVAMVERLLAMGADPNRQDRKGTTALMEAVATDHAELIDRL 282
Score = 32.0 bits (71), Expect = 1.3
Identities = 23/81 (28%), Positives = 41/81 (50%), Gaps = 1/81 (1%)
Frame = +3
Query: 3 KSLSLLIECGASIHDKSDNDNPWDSEADFSPLMFATYHGHSKLVEGLIDSGAKVNKGDRK 182
++++LL+ GA ++ ++ A +PL FA GH + L++ GA V+ R
Sbjct: 79 ETVALLLSRGADVNART--------VAGCTPLTFAAEAGHIGISALLLERGAHVHDRTRS 130
Query: 183 GWTCLHGAA-HRCHEKIVKLL 242
GW L A+ H + + +LL
Sbjct: 131 GWDALMIASRHGITDMVEQLL 151
>sp|Q8WWH4|ASZ1_HUMAN Ankyrin repeat, SAM and basic leucine zipper domain-containing
protein 1 (Germ cell-specific ankyrin, SAM and basic
leucine zipper domain containing protein)
Length = 475
Score = 44.3 bits (103), Expect = 3e-04
Identities = 26/72 (36%), Positives = 40/72 (55%)
Frame = +3
Query: 90 SPLMFATYHGHSKLVEGLIDSGAKVNKGDRKGWTCLHGAAHRCHEKIVKLL*FLVHILKQ 269
+P+M+A GH+++V L+ GA+VN D G+T L AA + H+ IV
Sbjct: 151 TPIMYAARDGHTQVVALLVAHGAEVNTQDENGYTALTWAARQGHKNIV-----------L 199
Query: 270 ELIEAKLHKMLQ 305
+L+E +KMLQ
Sbjct: 200 KLLELGANKMLQ 211
Score = 31.2 bits (69), Expect = 2.3
Identities = 16/42 (38%), Positives = 25/42 (59%)
Frame = +3
Query: 117 GHSKLVEGLIDSGAKVNKGDRKGWTCLHGAAHRCHEKIVKLL 242
G LV+ L+DSG V+ + GWT L AA + ++V++L
Sbjct: 57 GDVSLVQELLDSGISVDSNFQYGWTPLMYAASVANAELVRVL 98
>sp|Q8WMX6|ASZ1_PANTR Ankyrin repeat, SAM and basic leucine zipper domain-containing
protein 1 (Germ cell-specific ankyrin, SAM and basic
leucine zipper domain containing protein)
Length = 475
Score = 44.3 bits (103), Expect = 3e-04
Identities = 26/72 (36%), Positives = 40/72 (55%)
Frame = +3
Query: 90 SPLMFATYHGHSKLVEGLIDSGAKVNKGDRKGWTCLHGAAHRCHEKIVKLL*FLVHILKQ 269
+P+M+A GH+++V L+ GA+VN D G+T L AA + H+ IV
Sbjct: 151 TPIMYAARDGHTQVVALLVAHGAEVNTQDENGYTALTWAARQGHKNIV-----------L 199
Query: 270 ELIEAKLHKMLQ 305
+L+E +KMLQ
Sbjct: 200 KLLELGANKMLQ 211
Score = 30.4 bits (67), Expect = 3.9
Identities = 16/42 (38%), Positives = 25/42 (59%)
Frame = +3
Query: 117 GHSKLVEGLIDSGAKVNKGDRKGWTCLHGAAHRCHEKIVKLL 242
G LV+ L+DSG V+ + GWT L AA + ++V++L
Sbjct: 57 GDVSLVQELLDSGISVDSTFQYGWTPLMYAASVANAELVRVL 98
>sp|Q12955|ANK3_HUMAN Ankyrin-3 (ANK-3) (Ankyrin G)
Length = 4377
Score = 43.9 bits (102), Expect = 3e-04
Identities = 21/53 (39%), Positives = 34/53 (64%)
Frame = +3
Query: 84 DFSPLMFATYHGHSKLVEGLIDSGAKVNKGDRKGWTCLHGAAHRCHEKIVKLL 242
D +PL A+ G++ +V+ L+D GAK++ R G T LH A HE++V++L
Sbjct: 268 DITPLHVASKRGNANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEML 320
Score = 40.8 bits (94), Expect = 0.003
Identities = 19/52 (36%), Positives = 31/52 (59%)
Frame = +3
Query: 87 FSPLMFATYHGHSKLVEGLIDSGAKVNKGDRKGWTCLHGAAHRCHEKIVKLL 242
++PL ++G+ K+V L+ AKVN + G+T LH AA + H I+ +L
Sbjct: 731 YTPLHVGCHYGNIKIVNFLLQHSAKVNAKTKNGYTPLHQAAQQGHTHIINVL 782
Score = 40.0 bits (92), Expect = 0.005
Identities = 23/78 (29%), Positives = 42/78 (53%)
Frame = +3
Query: 9 LSLLIECGASIHDKSDNDNPWDSEADFSPLMFATYHGHSKLVEGLIDSGAKVNKGDRKGW 188
+ +L+ GA+++ +S N F+PL A H ++V+ L+D+GA + G+
Sbjct: 123 VKVLVTNGANVNAQSQNG--------FTPLYMAAQENHLEVVKFLLDNGASQSLATEDGF 174
Query: 189 TCLHGAAHRCHEKIVKLL 242
T L A + H+++V LL
Sbjct: 175 TPLAVALQQGHDQVVSLL 192
Score = 38.9 bits (89), Expect = 0.011
Identities = 25/80 (31%), Positives = 40/80 (50%)
Frame = +3
Query: 3 KSLSLLIECGASIHDKSDNDNPWDSEADFSPLMFATYHGHSKLVEGLIDSGAKVNKGDRK 182
K + LL++ GASI + E+ +P+ A + GH +V L+ GA N + +
Sbjct: 414 KVMELLLKHGASIQAVT--------ESGLTPIHVAAFMGHVNIVSQLMHHGASPNTTNVR 465
Query: 183 GWTCLHGAAHRCHEKIVKLL 242
G T LH AA ++V+ L
Sbjct: 466 GETALHMAARSGQAEVVRYL 485
Score = 37.0 bits (84), Expect = 0.042
Identities = 21/65 (32%), Positives = 38/65 (58%)
Frame = +3
Query: 48 KSDNDNPWDSEADFSPLMFATYHGHSKLVEGLIDSGAKVNKGDRKGWTCLHGAAHRCHEK 227
++DN+ +S++ F+PL A ++G+ + L++ A V+ R T LH A+ R +
Sbjct: 223 QNDNNADVESKSGFTPLHIAAHYGNINVATLLLNRAAAVDFTARNDITPLHVASKRGNAN 282
Query: 228 IVKLL 242
+VKLL
Sbjct: 283 MVKLL 287
Score = 36.2 bits (82), Expect = 0.071
Identities = 21/75 (28%), Positives = 35/75 (46%)
Frame = +3
Query: 18 LIECGASIHDKSDNDNPWDSEADFSPLMFATYHGHSKLVEGLIDSGAKVNKGDRKGWTCL 197
L++ GA + K+ +D +PL + G + +V+ L+ GA N G+T L
Sbjct: 485 LVQDGAQVEAKAKDDQ--------TPLHISARLGKADIVQQLLQQGASPNAATTSGYTPL 536
Query: 198 HGAAHRCHEKIVKLL 242
H +A HE + L
Sbjct: 537 HLSAREGHEDVAAFL 551
Score = 35.0 bits (79), Expect = 0.16
Identities = 18/49 (36%), Positives = 30/49 (61%)
Frame = +3
Query: 96 LMFATYHGHSKLVEGLIDSGAKVNKGDRKGWTCLHGAAHRCHEKIVKLL 242
L A+ G +++V+ L+ +GA VN + G+T L+ AA H ++VK L
Sbjct: 111 LHIASLAGQAEVVKVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVKFL 159
Score = 33.1 bits (74), Expect = 0.60
Identities = 24/78 (30%), Positives = 34/78 (43%)
Frame = +3
Query: 9 LSLLIECGASIHDKSDNDNPWDSEADFSPLMFATYHGHSKLVEGLIDSGAKVNKGDRKGW 188
+ +L++ A I K+ N SPL AT H V+ L+ V+
Sbjct: 317 VEMLLDRAAPILSKTKNG--------LSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYL 368
Query: 189 TCLHGAAHRCHEKIVKLL 242
T LH AAH H K+ K+L
Sbjct: 369 TALHVAAHCGHYKVAKVL 386
Score = 33.1 bits (74), Expect = 0.60
Identities = 17/52 (32%), Positives = 28/52 (53%)
Frame = +3
Query: 87 FSPLMFATYHGHSKLVEGLIDSGAKVNKGDRKGWTCLHGAAHRCHEKIVKLL 242
++PL + GH + L+D GA ++ +KG+T LH AA ++ LL
Sbjct: 533 YTPLHLSAREGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGKLEVANLL 584
Score = 33.1 bits (74), Expect = 0.60
Identities = 23/76 (30%), Positives = 34/76 (44%)
Frame = +3
Query: 15 LLIECGASIHDKSDNDNPWDSEADFSPLMFATYHGHSKLVEGLIDSGAKVNKGDRKGWTC 194
LL++ GAS H + N ++PL A + L++ GA N R+G
Sbjct: 616 LLLDQGASPHAAAKNG--------YTPLHIAAKKNQMDIATTLLEYGADANAVTRQGIAS 667
Query: 195 LHGAAHRCHEKIVKLL 242
+H AA H +V LL
Sbjct: 668 VHLAAQEGHVDMVSLL 683
Score = 32.7 bits (73), Expect = 0.78
Identities = 23/78 (29%), Positives = 36/78 (46%)
Frame = +3
Query: 9 LSLLIECGASIHDKSDNDNPWDSEADFSPLMFATYHGHSKLVEGLIDSGAKVNKGDRKGW 188
+ LL++ GA I K+ + +PL GH ++VE L+D A + + G
Sbjct: 284 VKLLLDRGAKIDAKTRDG--------LTPLHCGARSGHEQVVEMLLDRAAPILSKTKNGL 335
Query: 189 TCLHGAAHRCHEKIVKLL 242
+ LH A H V+LL
Sbjct: 336 SPLHMATQGDHLNCVQLL 353
Score = 32.3 bits (72), Expect = 1.0
Identities = 17/52 (32%), Positives = 27/52 (51%)
Frame = +3
Query: 87 FSPLMFATYHGHSKLVEGLIDSGAKVNKGDRKGWTCLHGAAHRCHEKIVKLL 242
F+PL A +G ++ L+ A + + G T LH AAH ++K+ LL
Sbjct: 566 FTPLHVAAKYGKLEVANLLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLL 617
Score = 32.0 bits (71), Expect = 1.3
Identities = 17/56 (30%), Positives = 28/56 (50%)
Frame = +3
Query: 75 SEADFSPLMFATYHGHSKLVEGLIDSGAKVNKGDRKGWTCLHGAAHRCHEKIVKLL 242
+++ +PL A + E L++ GA V+ + G+T LH H + KIV L
Sbjct: 694 NKSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIKIVNFL 749
Score = 30.8 bits (68), Expect = 3.0
Identities = 17/49 (34%), Positives = 27/49 (55%)
Frame = +3
Query: 96 LMFATYHGHSKLVEGLIDSGAKVNKGDRKGWTCLHGAAHRCHEKIVKLL 242
L A+ GH ++V L+ A V+ +KG T LH A+ ++VK+L
Sbjct: 78 LHLASKEGHVEVVSELLQREANVDAATKKGNTALHIASLAGQAEVVKVL 126
Score = 29.6 bits (65), Expect = 6.6
Identities = 17/49 (34%), Positives = 26/49 (53%)
Frame = +3
Query: 96 LMFATYHGHSKLVEGLIDSGAKVNKGDRKGWTCLHGAAHRCHEKIVKLL 242
L A + GH K+ + L+D A N G+T LH A + K+++LL
Sbjct: 371 LHVAAHCGHYKVAKVLLDKKANPNAKALNGFTPLHIACKKNRIKVMELL 419
Score = 29.3 bits (64), Expect = 8.7
Identities = 14/46 (30%), Positives = 26/46 (56%)
Frame = +3
Query: 78 EADFSPLMFATYHGHSKLVEGLIDSGAKVNKGDRKGWTCLHGAAHR 215
++ +PL A ++ + K+ L+D GA + + G+T LH AA +
Sbjct: 596 KSGLTPLHVAAHYDNQKVALLLLDQGASPHAAAKNGYTPLHIAAKK 641
>sp|Q9D2J7|ANKR5_MOUSE Ankyrin repeat domain protein 5
Length = 775
Score = 43.5 bits (101), Expect = 4e-04
Identities = 31/79 (39%), Positives = 40/79 (50%)
Frame = +3
Query: 6 SLSLLIECGASIHDKSDNDNPWDSEADFSPLMFATYHGHSKLVEGLIDSGAKVNKGDRKG 185
SL IE G + K DN + + PLM A G+ +V+ LI+ GA VN D
Sbjct: 507 SLKKAIETGIPVDMK---DNTYKT-----PLMIACASGNIDVVKFLIEKGANVNATDNFL 558
Query: 186 WTCLHGAAHRCHEKIVKLL 242
WT LH A H + IV+LL
Sbjct: 559 WTPLHFACHAGQQDIVELL 577
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 62,935,165
Number of Sequences: 369166
Number of extensions: 1133605
Number of successful extensions: 3443
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3010
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3433
length of database: 68,354,980
effective HSP length: 106
effective length of database: 48,773,070
effective search space used: 5023626210
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)