Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_016_D05
(790 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P19351|TNNT_DROME Troponin T, skeletal muscle (Upheld pr... 100 5e-21
sp|Q9XZ71|TNNT_PERAM Troponin T (TnT) 93 9e-19
sp|Q27371|TNNT_CAEEL Troponin T 76 9e-14
sp|P09741|TNNT2_RABIT Troponin T, cardiac muscle (TnTc) (Ca... 62 2e-09
sp|P45379|TNNT2_HUMAN Troponin T, cardiac muscle (TnTc) (Ca... 62 2e-09
sp|P50752|TNNT2_MOUSE Troponin T, cardiac muscle (TnTc) (Ca... 62 2e-09
sp|P50751|TNNT2_SHEEP Troponin T, cardiac muscle (TnTc) (Ca... 60 7e-09
sp|P13789|TNNT2_BOVIN Troponin T, cardiac muscle (TnTc) (Ca... 60 9e-09
sp|P50753|TNNT2_RAT Troponin T, cardiac muscle (TnTc) (Card... 59 1e-08
sp|P02642|TNNT2_CHICK Troponin T, cardiac muscle isoforms (... 59 1e-08
>sp|P19351|TNNT_DROME Troponin T, skeletal muscle (Upheld protein) (Intended thorax
protein)
Length = 397
Score = 100 bits (249), Expect = 5e-21
Identities = 75/206 (36%), Positives = 105/206 (50%), Gaps = 15/206 (7%)
Frame = +3
Query: 12 PNFIINKRANNELEKDEPTKEEVAKSKEQLEAERKAILEQRIQALVIDGFDLQKLKEKAK 191
PNF I K+ L E K+KEQLE E+K L RI+ L I+GF KL+EKA+
Sbjct: 144 PNFTIAKKDAGVLGLSSAAMER-NKTKEQLEEEKKISLSFRIKPLAIEGFGEAKLREKAQ 202
Query: 192 ELHQNIYKLESEKYDLEQQFQRQTLDLMELAERARQMNKGGKGQKVNVAQTDALPTKMSR 371
EL + I KLE+EKYDLE++ +RQ DL EL ER +Q + K K + +AL K
Sbjct: 203 ELWELIVKLETEKYDLEERQKRQDYDLKELKERQKQQLR-HKALKKGL-DPEALTGKY-- 258
Query: 372 APPKVVMYSQYERVKDPRSFRDRSTVFDG---------------PLYSDYFTKIEPRFKV 506
PPK+ + S+YER D RS+ D+ +F+G Y + + +
Sbjct: 259 -PPKIQVASKYERRVDTRSYDDKKKLFEGGWDEISKDSNEKIWNEKKEQYTGRQKSKLPK 317
Query: 507 HMGEQGGEVVTENDAHHGSEAPAANE 584
GE+ G+ E + G E A+E
Sbjct: 318 WFGERPGKKAGEPETPEGEEDAKADE 343
>sp|Q9XZ71|TNNT_PERAM Troponin T (TnT)
Length = 384
Score = 92.8 bits (229), Expect = 9e-19
Identities = 63/149 (42%), Positives = 87/149 (58%)
Frame = +3
Query: 12 PNFIINKRANNELEKDEPTKEEVAKSKEQLEAERKAILEQRIQALVIDGFDLQKLKEKAK 191
PNF I K+ + + E K+KEQLE E+K L RI+ L I+ ++ KLK KA
Sbjct: 142 PNFTIQKK--DPSFNMSSAQIERNKTKEQLEEEKKISLSFRIKPLEIENLNVDKLKVKAT 199
Query: 192 ELHQNIYKLESEKYDLEQQFQRQTLDLMELAERARQMNKGGKGQKVNVAQTDALPTKMSR 371
EL I KLE+EKYDLE++ +RQ DL EL ER +Q + K K + +AL K
Sbjct: 200 ELWDAIVKLETEKYDLEERQKRQDYDLKELKERQKQQLR-HKALKKGL-DPEALTGKY-- 255
Query: 372 APPKVVMYSQYERVKDPRSFRDRSTVFDG 458
PPK+ + S+YER D RS+ D+ +F+G
Sbjct: 256 -PPKIQVASKYERRVDTRSYDDKKKLFEG 283
>sp|Q27371|TNNT_CAEEL Troponin T
Length = 405
Score = 76.3 bits (186), Expect = 9e-14
Identities = 47/125 (37%), Positives = 69/125 (55%)
Frame = +3
Query: 87 SKEQLEAERKAILEQRIQALVIDGFDLQKLKEKAKELHQNIYKLESEKYDLEQQFQRQTL 266
SKEQ+E ++ L + + G LKE+ + LH I KLE+EKYDLE++ +RQ
Sbjct: 203 SKEQMEDAKRNFLAAVCRVQDVSGLLPNDLKERIRGLHARIVKLEAEKYDLEKRRERQDY 262
Query: 267 DLMELAERARQMNKGGKGQKVNVAQTDALPTKMSRAPPKVVMYSQYERVKDPRSFRDRST 446
D+ EL ER RQ + K K + +A S PPK+ S+++R D RS+ DR
Sbjct: 263 DMKELHERQRQAAR-NKALKKGLDPEEA---ASSVHPPKITTASKFDRQTDRRSYGDRRY 318
Query: 447 VFDGP 461
+F+ P
Sbjct: 319 LFENP 323
>sp|P09741|TNNT2_RABIT Troponin T, cardiac muscle (TnTc) (Cardiac muscle troponin T)
(cTnT)
Length = 301
Score = 62.0 bits (149), Expect = 2e-09
Identities = 32/90 (35%), Positives = 56/90 (62%)
Frame = +3
Query: 48 LEKDEPTKEEVAKSKEQLEAERKAILEQRIQALVIDGFDLQKLKEKAKELHQNIYKLESE 227
++K T+ + K + + E ++K + E+R + L ID + +L+EKAKEL Q+IY LE+E
Sbjct: 201 IQKQAQTERKSGKRQTEREKKKKILAERR-KVLAIDHLNEDQLREKAKELWQSIYNLEAE 259
Query: 228 KYDLEQQFQRQTLDLMELAERARQMNKGGK 317
K+DL+++F++Q ++ L R K K
Sbjct: 260 KFDLQEKFKQQKYEINVLRNRINDNQKVSK 289
>sp|P45379|TNNT2_HUMAN Troponin T, cardiac muscle (TnTc) (Cardiac muscle troponin T)
(cTnT)
Length = 298
Score = 62.0 bits (149), Expect = 2e-09
Identities = 32/90 (35%), Positives = 56/90 (62%)
Frame = +3
Query: 48 LEKDEPTKEEVAKSKEQLEAERKAILEQRIQALVIDGFDLQKLKEKAKELHQNIYKLESE 227
++K T+ + K + + E ++K + E+R + L ID + +L+EKAKEL Q+IY LE+E
Sbjct: 198 IQKQAQTERKSGKRQTEREKKKKILAERR-KVLAIDHLNEDQLREKAKELWQSIYNLEAE 256
Query: 228 KYDLEQQFQRQTLDLMELAERARQMNKGGK 317
K+DL+++F++Q ++ L R K K
Sbjct: 257 KFDLQEKFKQQKYEINVLRNRINDNQKVSK 286
>sp|P50752|TNNT2_MOUSE Troponin T, cardiac muscle (TnTc) (Cardiac muscle troponin T)
(cTnT)
Length = 301
Score = 61.6 bits (148), Expect = 2e-09
Identities = 32/90 (35%), Positives = 57/90 (63%)
Frame = +3
Query: 48 LEKDEPTKEEVAKSKEQLEAERKAILEQRIQALVIDGFDLQKLKEKAKELHQNIYKLESE 227
++K T+ + K + + E ++K + E+R +AL ID + +L+EKAKEL Q+I+ LE+E
Sbjct: 201 IQKQAQTERKSGKRQTEREKKKKILAERR-KALAIDHLNEDQLREKAKELWQSIHNLEAE 259
Query: 228 KYDLEQQFQRQTLDLMELAERARQMNKGGK 317
K+DL+++F++Q ++ L R K K
Sbjct: 260 KFDLQEKFKQQKYEINVLRNRINDNQKVSK 289
>sp|P50751|TNNT2_SHEEP Troponin T, cardiac muscle (TnTc) (Cardiac muscle troponin T)
(cTnT)
Length = 287
Score = 60.1 bits (144), Expect = 7e-09
Identities = 33/87 (37%), Positives = 52/87 (59%), Gaps = 1/87 (1%)
Frame = +3
Query: 60 EPTKEEVAKSKEQLEAERKA-ILEQRIQALVIDGFDLQKLKEKAKELHQNIYKLESEKYD 236
+ + E K Q E E+K IL +R + L ID + +L+EKA+EL Q+IY LE+EK+D
Sbjct: 189 QKAQAERKSGKRQTEREKKKKILAERRKVLAIDHLNEDQLREKARELWQSIYDLEAEKFD 248
Query: 237 LEQQFQRQTLDLMELAERARQMNKGGK 317
L+++F++Q ++ L R K K
Sbjct: 249 LQEKFKQQKYEINVLRNRVNDNQKVSK 275
>sp|P13789|TNNT2_BOVIN Troponin T, cardiac muscle (TnTc) (Cardiac muscle troponin T)
(cTnT)
Length = 285
Score = 59.7 bits (143), Expect = 9e-09
Identities = 34/87 (39%), Positives = 51/87 (58%), Gaps = 1/87 (1%)
Frame = +3
Query: 60 EPTKEEVAKSKEQLEAERKA-ILEQRIQALVIDGFDLQKLKEKAKELHQNIYKLESEKYD 236
+ + E K Q E E+K IL +R + L ID + +L+EKAKEL Q IY LE+EK+D
Sbjct: 187 QKAQTERKSGKRQTEREKKKKILAERRKVLAIDHLNEDQLREKAKELWQMIYDLEAEKFD 246
Query: 237 LEQQFQRQTLDLMELAERARQMNKGGK 317
L+++F++Q ++ L R K K
Sbjct: 247 LQEKFKQQKYEINVLRNRINDNQKVSK 273
>sp|P50753|TNNT2_RAT Troponin T, cardiac muscle (TnTc) (Cardiac muscle troponin T)
(cTnT)
Length = 299
Score = 59.3 bits (142), Expect = 1e-08
Identities = 33/87 (37%), Positives = 52/87 (59%), Gaps = 1/87 (1%)
Frame = +3
Query: 60 EPTKEEVAKSKEQLEAERKA-ILEQRIQALVIDGFDLQKLKEKAKELHQNIYKLESEKYD 236
+ + E K Q E E+K IL +R + L ID + +L+EKAKEL Q+I+ LE+EK+D
Sbjct: 201 QKAQTERKSGKRQTEREKKKKILAERRKVLAIDHLNEDQLREKAKELWQSIHNLEAEKFD 260
Query: 237 LEQQFQRQTLDLMELAERARQMNKGGK 317
L+++F++Q ++ L R K K
Sbjct: 261 LQEKFKQQKYEINVLRNRINDNQKVSK 287
>sp|P02642|TNNT2_CHICK Troponin T, cardiac muscle isoforms (TnTC)
Length = 302
Score = 59.3 bits (142), Expect = 1e-08
Identities = 37/89 (41%), Positives = 52/89 (58%), Gaps = 3/89 (3%)
Frame = +3
Query: 69 KEEVAKSKEQLEAERKA-ILEQRIQALVIDGFDLQKLKEKAKELHQNIYKLESEKYDLEQ 245
K E K+Q E E+K IL +R + L ID KL++KAKEL Q I LE+EK+DL++
Sbjct: 204 KSEKKGGKKQTEREKKKKILSERRKPLNIDHLSEDKLRDKAKELWQTIRDLEAEKFDLQE 263
Query: 246 QFQRQTLDLMELAERA--RQMNKGGKGQK 326
+F+RQ ++ L R Q KG K +
Sbjct: 264 KFKRQKYEINVLRNRVSDHQKVKGSKAAR 292
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 83,338,406
Number of Sequences: 369166
Number of extensions: 1711971
Number of successful extensions: 6584
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 5988
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6518
length of database: 68,354,980
effective HSP length: 108
effective length of database: 48,403,600
effective search space used: 7454154400
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)