Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= Dr_sW_016_C01 (847 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|Q9NRA2|S17A5_HUMAN Sialin (Solute carrier family 17 memb... 209 8e-54 sp|Q8BN82|S17A5_MOUSE Sialin (Solute carrier family 17 memb... 206 7e-53 sp|Q9MZD1|S17A5_SHEEP Sialin (Solute carrier family 17 memb... 204 2e-52 sp|Q03567|YLD2_CAEEL Hypothetical protein C38C10.2 in chrom... 172 8e-43 sp|O61369|PICO_DROAN Putative inorganic phosphate cotranspo... 170 4e-42 sp|Q9V7S5|PICO_DROME Putative inorganic phosphate cotranspo... 168 2e-41 sp|P34644|YOQ6_CAEEL Hypothetical protein ZK512.6 in chromo... 161 2e-39 sp|Q61983|NPT1_MOUSE Renal sodium-dependent phosphate trans... 145 1e-34 sp|Q62795|NPT1_RAT Renal sodium-dependent phosphate transpo... 145 2e-34 sp|Q14916|NPT1_HUMAN Renal sodium-dependent phosphate trans... 144 4e-34
>sp|Q9NRA2|S17A5_HUMAN Sialin (Solute carrier family 17 member 5) (Sodium/sialic acid cotransporter) (AST) (Membrane glycoprotein HP59) Length = 495 Score = 209 bits (532), Expect = 8e-54 Identities = 112/280 (40%), Positives = 161/280 (57%), Gaps = 2/280 (0%) Frame = +2 Query: 2 AVKIGGKWFFGIGVXXXXXXXXXXXXAARAGYGWLIALRVLEGAGESITYPAMHTMLGYW 181 A KIGGK G G+ AA G G LI LR LEG GE +T+PAMH M W Sbjct: 130 ASKIGGKMLLGFGILGTAVLTLFTPIAADLGVGPLIVLRALEGLGEGVTFPAMHAMWSSW 189 Query: 182 APAMETTFIGGIVYSGSFXXXXXXXXXXXXXXDANVMGGWPSVFYIPGIVGVLWFIIWSF 361 AP +E + + I Y+G+ W VFY G +G+ WF++W + Sbjct: 190 APPLERSKLLSISYAGAQLGTVISLPLSGIIC---YYMNWTYVFYFFGTIGIFWFLLWIW 246 Query: 362 VAYSTPAHHPRISEKEKRFIESSVN--LSAEEKHTNVPWKQIMLSVPVWAISIANFCAMW 535 + TP H RIS EK +I SS+ LS+++ +VPW I+ S+P+WAI +A+F W Sbjct: 247 LVSDTPQKHKRISHYEKEYILSSLRNQLSSQK---SVPWVPILKSLPLWAIVVAHFSYNW 303 Query: 536 SLYTLLTSLPQFFEYVLGFSISENGYINALPYFLSAITFVLSGKLADIIRSRKWMSTTVT 715 + YTLLT LP + + +L F++ ENG++++LPY S + +LSG+ AD +R++ ST Sbjct: 304 TFYTLLTLLPTYMKEILRFNVQENGFLSSLPYLGSWLCMILSGQAADNLRAKWNFSTLCV 363 Query: 716 RKLFNTIGMLVNAIFIVAISFIGCDKVLVVTFLCIAVAVG 835 R++F+ IGM+ A+F+VA FIGCD L V FL I+ +G Sbjct: 364 RRIFSLIGMIGPAVFLVAAGFIGCDYSLAVAFLTISTTLG 403
>sp|Q8BN82|S17A5_MOUSE Sialin (Solute carrier family 17 member 5) (Sodium/sialic acid cotransporter) Length = 495 Score = 206 bits (524), Expect = 7e-53 Identities = 108/278 (38%), Positives = 156/278 (56%) Frame = +2 Query: 2 AVKIGGKWFFGIGVXXXXXXXXXXXXAARAGYGWLIALRVLEGAGESITYPAMHTMLGYW 181 A ++GGK G+G+ AA G L+ LR LEG GE +T+PAMH M W Sbjct: 130 ASRVGGKLLLGLGILGTSVFTLFTPLAADLGVVTLVVLRALEGLGEGVTFPAMHAMWSSW 189 Query: 182 APAMETTFIGGIVYSGSFXXXXXXXXXXXXXXDANVMGGWPSVFYIPGIVGVLWFIIWSF 361 AP +E + + I Y+G+ W VFY+ GIVG++WFI+W + Sbjct: 190 APPLERSKLLTISYAGAQLGTVISLPLSGIIC---YYMNWTYVFYLFGIVGIVWFILWMW 246 Query: 362 VAYSTPAHHPRISEKEKRFIESSVNLSAEEKHTNVPWKQIMLSVPVWAISIANFCAMWSL 541 + TP H IS EK +I SS+ + VPW I+ S+P+WAI +A+F WS Sbjct: 247 IVSDTPETHKTISHYEKEYIVSSLKNQLSSQKV-VPWGSILKSLPLWAIVVAHFSYNWSF 305 Query: 542 YTLLTSLPQFFEYVLGFSISENGYINALPYFLSAITFVLSGKLADIIRSRKWMSTTVTRK 721 YTLLT LP + + +L F++ ENG+++ALPYF + +L G+ AD +R + ST R+ Sbjct: 306 YTLLTLLPTYMKEILRFNVQENGFLSALPYFGCWLCMILCGQAADYLRVKWNFSTISVRR 365 Query: 722 LFNTIGMLVNAIFIVAISFIGCDKVLVVTFLCIAVAVG 835 +F+ +GM+ A+F+VA FIGCD L V FL I+ +G Sbjct: 366 IFSLVGMVGPAVFLVAAGFIGCDYSLAVAFLTISTTLG 403
>sp|Q9MZD1|S17A5_SHEEP Sialin (Solute carrier family 17 member 5) (Sodium/sialic acid cotransporter) (Membrane glycoprotein SP55) Length = 495 Score = 204 bits (519), Expect = 2e-52 Identities = 114/280 (40%), Positives = 160/280 (57%), Gaps = 2/280 (0%) Frame = +2 Query: 2 AVKIGGKWFFGIGVXXXXXXXXXXXXAARAGYGWLIALRVLEGAGESITYPAMHTMLGYW 181 A + GGK G G+ AA G G L+ALR LEG GE +TYPAMH M W Sbjct: 130 ASRSGGKLLLGFGIFATAIFTLFTPLAADFGVGALVALRALEGLGEGVTYPAMHAMWSSW 189 Query: 182 APAMETTFIGGIVYSGSFXXXXXXXXXXXXXXDANVMGGWPSVFYIPGIVGVLWFIIWSF 361 AP +E + + I Y+G+ W VFY GIVG++WFI+W Sbjct: 190 APPLERSKLLSISYAGAQLGTVVSLPLSGVIC---YYMNWTYVFYFFGIVGIIWFILWIC 246 Query: 362 VAYSTPAHHPRISEKEKRFIESSVN--LSAEEKHTNVPWKQIMLSVPVWAISIANFCAMW 535 + TP H I+ EK +I SS+ LS+++ +VPW ++ S+P+WAI +A+F W Sbjct: 247 LVSDTPETHKTITPYEKEYILSSLKNQLSSQK---SVPWIPMLKSLPLWAIVVAHFSYNW 303 Query: 536 SLYTLLTSLPQFFEYVLGFSISENGYINALPYFLSAITFVLSGKLADIIRSRKWMSTTVT 715 + YTLLT LP + + VL F+I ENG+++A+PY + +LSG+ AD +R+R ST Sbjct: 304 TFYTLLTLLPTYMKEVLRFNIQENGFLSAVPYLGCWLCMILSGQAADNLRARWNFSTLWV 363 Query: 716 RKLFNTIGMLVNAIFIVAISFIGCDKVLVVTFLCIAVAVG 835 R++F+ IGM+ AIF+VA FIGCD L V FL I+ +G Sbjct: 364 RRVFSLIGMIGPAIFLVAAGFIGCDYSLAVAFLTISTTLG 403
>sp|Q03567|YLD2_CAEEL Hypothetical protein C38C10.2 in chromosome III Length = 493 Score = 172 bits (437), Expect = 8e-43 Identities = 95/281 (33%), Positives = 145/281 (51%), Gaps = 4/281 (1%) Frame = +2 Query: 2 AVKIGGKWFFGIGVXXXXXXXXXXXXAARAGYGWLIALRVLEGAGESITYPAMHTMLGYW 181 A + GGK + + AAR L LR G + T+PAMHTM W Sbjct: 105 ASRYGGKRVVFVTILGSALLTLLNPVAARTSEYALAILRAAIGFLQGATFPAMHTMWSVW 164 Query: 182 APAMETTFIGGIVYSGSFXXXXXXXXXXXXXXDANVMGGWPSVFYIPGIVGVLWFIIWSF 361 P +E + + G+ Y+G+ + GGWPS+FYI G+ GVLW +W + Sbjct: 165 GPPLELSVLTGVTYAGAQIGNVIVLPLSGFLCEYGFDGGWPSIFYIIGVFGVLWTAVWWY 224 Query: 362 VAYSTPAHHPRISEKEKRFIESSVNLSAEE---KHTNVPWKQIMLSVPVWAISIANFCAM 532 V+ PA HPRI+ +EK++I ++V S + K + PW +I+ S VWA +F Sbjct: 225 VSSDKPATHPRITPEEKQYIVTAVEASMGKDTGKVPSTPWIKILTSPAVWACWAGHFAGD 284 Query: 533 WSLYTLLTSLPQFFEYVLGFSISENGYINALPYFLSAITFVLSGKLADIIRSRKWMSTTV 712 W YT+L SLP F + VLG ++S G + ++PY + G LAD +RS+ +ST Sbjct: 285 WGAYTMLVSLPSFLKDVLGLNLSSLGAVASIPYIAYFLAINAGGVLADTLRSKGILSTLN 344 Query: 713 TRKLFNTIGMLVNAIFIVAISFIGCDK-VLVVTFLCIAVAV 832 TR+ + ++ IF+VA + GC + VLV+ F+ +A+ Sbjct: 345 TRRAAMLVALIGQGIFLVASGYCGCGQDVLVIIFITCGMAI 385
>sp|O61369|PICO_DROAN Putative inorganic phosphate cotransporter Length = 483 Score = 170 bits (431), Expect = 4e-42 Identities = 95/278 (34%), Positives = 142/278 (51%), Gaps = 1/278 (0%) Frame = +2 Query: 2 AVKIGGKWFFGIGVXXXXXXXXXXXXAARAGYGW-LIALRVLEGAGESITYPAMHTMLGY 178 A K G F G G+ AAR G W L A+R ++G GE P H ML Sbjct: 84 AKKYGSLRFLGYGMLINSVFAFLVPVAAREGGVWGLCAVRFIQGLGEGPIVPCTHAMLAK 143 Query: 179 WAPAMETTFIGGIVYSGSFXXXXXXXXXXXXXXDANVMGGWPSVFYIPGIVGVLWFIIWS 358 W P E + +G VY+G+ + GGWPS+FY+ GIVG +W I + Sbjct: 144 WIPPNERSRMGAAVYAGAQFGTIISMPLSGLLAEYGFDGGWPSIFYVFGIVGTVWSIAFL 203 Query: 359 FVAYSTPAHHPRISEKEKRFIESSVNLSAEEKHTNVPWKQIMLSVPVWAISIANFCAMWS 538 Y P+ HP+I E+EK++I S+ + K +P+K I+ S+P +AI A+ + Sbjct: 204 IFVYEDPSTHPKIDEREKKYINESLWGTDVIKSPPIPFKSIVKSLPFYAILFAHMGHNYG 263 Query: 539 LYTLLTSLPQFFEYVLGFSISENGYINALPYFLSAITFVLSGKLADIIRSRKWMSTTVTR 718 TL+T LP + + VL FS+ NG +++LPY + + +AD + S K S T TR Sbjct: 264 YETLMTELPTYMKQVLRFSLKSNGLLSSLPYLAMWLLSMFISVIADWMISSKRFSLTATR 323 Query: 719 KLFNTIGMLVNAIFIVAISFIGCDKVLVVTFLCIAVAV 832 K+ N+IG + ++A S+ GCD+ L + L I V + Sbjct: 324 KIINSIGQYGPGLALIAASYTGCDRALTLAILTIGVGL 361
>sp|Q9V7S5|PICO_DROME Putative inorganic phosphate cotransporter Length = 529 Score = 168 bits (425), Expect = 2e-41 Identities = 95/278 (34%), Positives = 141/278 (50%), Gaps = 1/278 (0%) Frame = +2 Query: 2 AVKIGGKWFFGIGVXXXXXXXXXXXXAARAGYGW-LIALRVLEGAGESITYPAMHTMLGY 178 A K G F G G+ AAR G W L A+R ++G GE P H ML Sbjct: 130 AKKYGSLRFLGYGMLINSVFAFLVPVAARGGGVWGLCAVRFIQGLGEGPIVPCTHAMLAK 189 Query: 179 WAPAMETTFIGGIVYSGSFXXXXXXXXXXXXXXDANVMGGWPSVFYIPGIVGVLWFIIWS 358 W P E + +G VY+G+ + GGWPS+FY+ GIVG +W I + Sbjct: 190 WIPPNERSRMGAAVYAGAQFGTIISMPLSGLLAEYGFDGGWPSIFYVFGIVGTVWSIAFL 249 Query: 359 FVAYSTPAHHPRISEKEKRFIESSVNLSAEEKHTNVPWKQIMLSVPVWAISIANFCAMWS 538 + P+ HP I E+EK++I S+ + K +P+K I+ S+P +AI A+ + Sbjct: 250 IFVHEDPSSHPTIDEREKKYINDSLWGTDVVKSPPIPFKAIIKSLPFYAILFAHMGHNYG 309 Query: 539 LYTLLTSLPQFFEYVLGFSISENGYINALPYFLSAITFVLSGKLADIIRSRKWMSTTVTR 718 TL+T LP + + VL FS+ NG +++LPY + + +AD + S K S T TR Sbjct: 310 YETLMTELPTYMKQVLRFSLKSNGLLSSLPYLAMWLFSMFISVVADWMISSKRFSHTATR 369 Query: 719 KLFNTIGMLVNAIFIVAISFIGCDKVLVVTFLCIAVAV 832 KL N+IG + ++A S+ GCD+ L + L I V + Sbjct: 370 KLINSIGQYGPGVALIAASYTGCDRALTLAILTIGVGL 407
>sp|P34644|YOQ6_CAEEL Hypothetical protein ZK512.6 in chromosome III Length = 576 Score = 161 bits (408), Expect = 2e-39 Identities = 85/265 (32%), Positives = 140/265 (52%), Gaps = 3/265 (1%) Frame = +2 Query: 29 FGIGVXXXXXXXXXXXXAARAGYGWLIA-LRVLEGAGESITYPAMHTMLGYWAPAMETTF 205 FGIGV ++ Y L+A +++ +G + + YPAMH + YWAP ME + Sbjct: 153 FGIGVGAFLNILLPYGFKVKSDY--LVAFIQITQGLVQGVCYPAMHGVWRYWAPPMERSK 210 Query: 206 IGGIVYSGSFXXXXXXXXXXXXXXDANVMGGWPSVFYIPGIVGVLWFIIWSFVAYSTPAH 385 + ++GS+ W + FY+ G+ GV+W I+W V + PA Sbjct: 211 LATTAFTGSYAGAVLGLPLSAFLVS---YVSWAAPFYLYGVCGVIWAILWFCVTFEKPAF 267 Query: 386 HPRISEKEKRFIESSVNLSAEEKHT--NVPWKQIMLSVPVWAISIANFCAMWSLYTLLTS 559 HP IS++EK FIE ++ + T ++PWK I+ S PVWAI +ANF W+ Y LL + Sbjct: 268 HPTISQEEKIFIEDAIGHVSNTHPTIRSIPWKAIVTSKPVWAIIVANFARSWTFYLLLQN 327 Query: 560 LPQFFEYVLGFSISENGYINALPYFLSAITFVLSGKLADIIRSRKWMSTTVTRKLFNTIG 739 + + LG I+++G + A+P+ + ++ G+LAD +RS K +STT RK+FN G Sbjct: 328 QLTYMKEALGMKIADSGLLAAIPHLVMGCVVLMGGQLADYLRSNKILSTTAVRKIFNCGG 387 Query: 740 MLVNAIFIVAISFIGCDKVLVVTFL 814 A F++ +++ D ++ + Sbjct: 388 FGGEAAFMLIVAYTTSDTTAIMALI 412
>sp|Q61983|NPT1_MOUSE Renal sodium-dependent phosphate transport protein 1 (Sodium/phosphate cotransporter 1) (Na(+)/PI cotransporter 1) (Renal sodium-phosphate transport protein 1) (Renal Na(+)-dependent phosphate cotransporter 1) (Solute carrier family 18 member 1) Length = 465 Score = 145 bits (367), Expect = 1e-34 Identities = 82/248 (33%), Positives = 127/248 (51%) Frame = +2 Query: 80 AARAGYGWLIALRVLEGAGESITYPAMHTMLGYWAPAMETTFIGGIVYSGSFXXXXXXXX 259 AA+ G +I RVL+G + H + WAP +E + + SG Sbjct: 126 AAQVGAALVIVCRVLQGIAQGTVSTGQHEIWVKWAPPLERGRLTSMTLSGFVMGPFIVLL 185 Query: 260 XXXXXXDANVMGGWPSVFYIPGIVGVLWFIIWSFVAYSTPAHHPRISEKEKRFIESSVNL 439 D + GWP VFYI GIVG + + W F+ + P HP +S EK +I SS+ Sbjct: 186 VSGFICD---LLGWPMVFYIFGIVGCVLSLSWFFLFFDDPKDHPYMSSSEKDYIISSLMQ 242 Query: 440 SAEEKHTNVPWKQIMLSVPVWAISIANFCAMWSLYTLLTSLPQFFEYVLGFSISENGYIN 619 A ++P K ++ S+P+WAI + +F +WS L+T P F VL ++ ENG ++ Sbjct: 243 QASSGRQSLPIKAMLKSLPLWAIILNSFAFIWSNSLLVTYTPTFISTVLHVNVRENGLLS 302 Query: 620 ALPYFLSAITFVLSGKLADIIRSRKWMSTTVTRKLFNTIGMLVNAIFIVAISFIGCDKVL 799 +LPY L+ I +L+G+++D +RK S RKLF T+G IFI+ + ++ + Sbjct: 303 SLPYLLAYICGILAGQMSDFFLTRKIFSIVTVRKLFTTLGSFCPVIFIMCLLYLSYNFYS 362 Query: 800 VVTFLCIA 823 V FL +A Sbjct: 363 TVIFLTLA 370
>sp|Q62795|NPT1_RAT Renal sodium-dependent phosphate transport protein 1 (Sodium/phosphate cotransporter 1) (Na(+)/PI cotransporter 1) (Renal sodium-phosphate transport protein 1) (Renal Na(+)-dependent phosphate cotransporter 1) (Solute carrier family 18 member 1) Length = 465 Score = 145 bits (365), Expect = 2e-34 Identities = 79/248 (31%), Positives = 127/248 (51%) Frame = +2 Query: 80 AARAGYGWLIALRVLEGAGESITYPAMHTMLGYWAPAMETTFIGGIVYSGSFXXXXXXXX 259 AA+ G +I RVL+G + H + WAP +E + + SG Sbjct: 126 AAQVGAALVIVCRVLQGIAQGAVSTGQHGIWVKWAPPLERGRLTSMTLSGFVMGPFIALL 185 Query: 260 XXXXXXDANVMGGWPSVFYIPGIVGVLWFIIWSFVAYSTPAHHPRISEKEKRFIESSVNL 439 D + GWP VFYI GIVG + + W + + P +HP +S EK +I SS+ Sbjct: 186 VSGFICD---LLGWPMVFYIFGIVGCVLSLFWFILLFDDPNNHPYMSSSEKDYITSSLMQ 242 Query: 440 SAEEKHTNVPWKQIMLSVPVWAISIANFCAMWSLYTLLTSLPQFFEYVLGFSISENGYIN 619 ++P K ++ S+P+WAI + +F +WS L+T P F L ++ ENG ++ Sbjct: 243 QVHSGRQSLPIKAMLKSLPLWAIILNSFAFIWSNNLLVTYTPTFISTTLHVNVRENGLLS 302 Query: 620 ALPYFLSAITFVLSGKLADIIRSRKWMSTTVTRKLFNTIGMLVNAIFIVAISFIGCDKVL 799 +LPY L+ I +++G+++D + SRK S RKLF T+G+ IF+V + ++ + Sbjct: 303 SLPYLLAYICGIVAGQMSDFLLSRKIFSVVAVRKLFTTLGIFCPVIFVVCLLYLSYNFYS 362 Query: 800 VVTFLCIA 823 V FL +A Sbjct: 363 TVIFLTLA 370
>sp|Q14916|NPT1_HUMAN Renal sodium-dependent phosphate transport protein 1 (Sodium/phosphate cotransporter 1) (Na(+)/PI cotransporter 1) (Renal sodium-phosphate transport protein 1) (Renal Na(+)-dependent phosphate cotransporter 1) (Solute carrier family 18 member 1) (NA/PI-4) Length = 465 Score = 144 bits (362), Expect = 4e-34 Identities = 83/253 (32%), Positives = 124/253 (49%) Frame = +2 Query: 80 AARAGYGWLIALRVLEGAGESITYPAMHTMLGYWAPAMETTFIGGIVYSGSFXXXXXXXX 259 AA G W++ R ++GA + I A + WAP +E + + SG Sbjct: 126 AAGIGVAWVVVCRAVQGAAQGIVATAQFEIYVKWAPPLERGRLTSMSTSGFLLGPFIVLL 185 Query: 260 XXXXXXDANVMGGWPSVFYIPGIVGVLWFIIWSFVAYSTPAHHPRISEKEKRFIESSVNL 439 ++ GWP VFYI G G ++W + Y P HP IS EK +I SS+ Sbjct: 186 VTGVICESL---GWPMVFYIFGACGCAVCLLWFVLFYDDPKDHPCISISEKEYITSSLVQ 242 Query: 440 SAEEKHTNVPWKQIMLSVPVWAISIANFCAMWSLYTLLTSLPQFFEYVLGFSISENGYIN 619 ++P K I+ S+PVWAISI +F WS + P F +L +I ENG+++ Sbjct: 243 QVSSSRQSLPIKAILKSLPVWAISIGSFTFFWSHNIMTLYTPMFINSMLHVNIKENGFLS 302 Query: 620 ALPYFLSAITFVLSGKLADIIRSRKWMSTTVTRKLFNTIGMLVNAIFIVAISFIGCDKVL 799 +LPY + I L+G+L+D +R +S RKLF G L+ AIF V + ++ Sbjct: 303 SLPYLFAWICGNLAGQLSDFFLTRNILSVIAVRKLFTAAGFLLPAIFGVCLPYLSSTFYS 362 Query: 800 VVTFLCIAVAVGT 838 +V FL +A A G+ Sbjct: 363 IVIFLILAGATGS 375
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 100,204,849 Number of Sequences: 369166 Number of extensions: 2143736 Number of successful extensions: 6100 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 5790 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 6050 length of database: 68,354,980 effective HSP length: 109 effective length of database: 48,218,865 effective search space used: 8293644780 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)