Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_016_B11
(791 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q20772|GCDH_CAEEL Probable glutaryl-CoA dehydrogenase, m... 359 4e-99
sp|P81140|GCDH_PIG Glutaryl-CoA dehydrogenase, mitochondria... 358 7e-99
sp|Q60759|GCDH_MOUSE Glutaryl-CoA dehydrogenase, mitochondr... 353 4e-97
sp|Q92947|GCDH_HUMAN Glutaryl-CoA dehydrogenase, mitochondr... 348 1e-95
sp|Q8HXX8|GCDH_MACFA Glutaryl-CoA dehydrogenase, mitochondr... 347 3e-95
sp|Q96329|ACOX4_ARATH Acyl-coenzyme A oxidase 4, peroxisoma... 140 5e-33
sp|Q06319|ACDS_MEGEL Acyl-CoA dehydrogenase, short-chain sp... 137 4e-32
sp|P52042|ACDS_CLOAB Acyl-CoA dehydrogenase, short-chain sp... 137 4e-32
sp|P45867|ACDA_BACSU Acyl-CoA dehydrogenase 133 5e-31
sp|Q9JHI5|IVD_MOUSE Isovaleryl-CoA dehydrogenase, mitochond... 130 3e-30
>sp|Q20772|GCDH_CAEEL Probable glutaryl-CoA dehydrogenase, mitochondrial precursor (GCD)
Length = 409
Score = 359 bits (922), Expect = 4e-99
Identities = 175/247 (70%), Positives = 204/247 (82%), Gaps = 1/247 (0%)
Frame = +1
Query: 1 SSLVMWPINEYGTQTQKDKFLPKLATGHLIGCFGLTEPNHGSNPGGMETRAKYNEKSKCY 180
+SLV+ PI YG++ QK K++P LA+G IGCFGLTEPNHGSNPGGMET+A ++E +K Y
Sbjct: 117 TSLVIGPIYNYGSEDQKQKYIPDLASGKKIGCFGLTEPNHGSNPGGMETKATWDETTKTY 176
Query: 181 VLNGSKTWITNSPIADVFIIWAKSDV-DNKIRGFILERGMKGLSTPVIEGKFSLRASITG 357
LNGSKTWI+NSP++DV ++WA+S +NKI+GFILERGMKGL+TP IEGK SLRASITG
Sbjct: 177 KLNGSKTWISNSPVSDVMVVWARSARHNNKIKGFILERGMKGLTTPKIEGKLSLRASITG 236
Query: 358 QISMEDVEVPADNMFPKITGLQGPFGCLNNARYGIGWGTLGAAEFCLETARNYTLDRNQF 537
QI+M+DV VP +N+ P GLQGPFGCLNNAR GI WG LGAAE C AR YTLDR QF
Sbjct: 237 QIAMDDVPVPEENLLPNAEGLQGPFGCLNNARLGIAWGALGAAEECFHLARQYTLDRQQF 296
Query: 538 SKPLAKNQLIQKKLADMLTEISIGLQACLRVGRLKDEGLVTPEMISIIKRNSCGKALECA 717
+PLA+NQL+Q K+ADMLTEIS+GLQ CLRV RLKDEG V E ISIIKRNSCGKALE A
Sbjct: 297 GRPLAQNQLMQLKMADMLTEISLGLQGCLRVSRLKDEGKVQSEQISIIKRNSCGKALEVA 356
Query: 718 RMARDML 738
R ARDML
Sbjct: 357 RKARDML 363
>sp|P81140|GCDH_PIG Glutaryl-CoA dehydrogenase, mitochondrial precursor (GCD)
Length = 408
Score = 358 bits (920), Expect = 7e-99
Identities = 172/247 (69%), Positives = 207/247 (83%), Gaps = 1/247 (0%)
Frame = +1
Query: 1 SSLVMWPINEYGTQTQKD-KFLPKLATGHLIGCFGLTEPNHGSNPGGMETRAKYNEKSKC 177
SSLVM PI YG++ Q+ K+LP+LA G L+GCFGLTEPNHGS+PG METRA +N ++
Sbjct: 114 SSLVMHPIYAYGSEEQQQQKYLPRLAKGELLGCFGLTEPNHGSDPGSMETRALHNPSNRS 173
Query: 178 YVLNGSKTWITNSPIADVFIIWAKSDVDNKIRGFILERGMKGLSTPVIEGKFSLRASITG 357
Y LNG+KTWITNSP+AD+F++WA+ + DN IRGF+LE+GM+GLS P IEGKFSLRAS TG
Sbjct: 174 YTLNGAKTWITNSPVADLFVVWARCE-DNCIRGFLLEKGMRGLSAPKIEGKFSLRASATG 232
Query: 358 QISMEDVEVPADNMFPKITGLQGPFGCLNNARYGIGWGTLGAAEFCLETARNYTLDRNQF 537
I M+DVEVP +N+ PK + L PFGCLNNARYGI WG LGAAEFCL TAR YTLDR QF
Sbjct: 233 MIIMDDVEVPEENVLPKASSLAVPFGCLNNARYGISWGVLGAAEFCLHTARQYTLDRIQF 292
Query: 538 SKPLAKNQLIQKKLADMLTEISIGLQACLRVGRLKDEGLVTPEMISIIKRNSCGKALECA 717
PLAKNQLIQ+KLADMLTEI++GL ACL++GRLKD+ VTPEM+S++KRN+CGKAL+ A
Sbjct: 293 GVPLAKNQLIQRKLADMLTEITLGLHACLQLGRLKDQDKVTPEMVSLLKRNNCGKALDIA 352
Query: 718 RMARDML 738
R ARDML
Sbjct: 353 RQARDML 359
Score = 31.2 bits (69), Expect = 3.4
Identities = 13/16 (81%), Positives = 14/16 (87%)
Frame = +2
Query: 743 NGISDEYHVIRHLLIL 790
NGISDEYHVIRH + L
Sbjct: 362 NGISDEYHVIRHAMNL 377
>sp|Q60759|GCDH_MOUSE Glutaryl-CoA dehydrogenase, mitochondrial precursor (GCD)
Length = 438
Score = 353 bits (905), Expect = 4e-97
Identities = 166/246 (67%), Positives = 204/246 (82%)
Frame = +1
Query: 1 SSLVMWPINEYGTQTQKDKFLPKLATGHLIGCFGLTEPNHGSNPGGMETRAKYNEKSKCY 180
SSLVM PI YG++ Q+ K+LP+LA G L+GCFGLTEPNHGS+PGGMETRA++N ++ Y
Sbjct: 145 SSLVMHPIYTYGSEEQRQKYLPRLAKGELLGCFGLTEPNHGSDPGGMETRARHNPSNQSY 204
Query: 181 VLNGSKTWITNSPIADVFIIWAKSDVDNKIRGFILERGMKGLSTPVIEGKFSLRASITGQ 360
L+G+KTWITNSP+AD+FI+WA+ + DN I GFILE+GM+G S P IEGKFSLRAS TG
Sbjct: 205 TLSGTKTWITNSPVADLFIVWARCE-DNCIPGFILEKGMRGSSAPRIEGKFSLRASATGM 263
Query: 361 ISMEDVEVPADNMFPKITGLQGPFGCLNNARYGIGWGTLGAAEFCLETARNYTLDRNQFS 540
I M+ VEVP +N+ P ++ L GPFGCLN ARYGI WG LGAAEFCL TAR Y LDR QF
Sbjct: 264 IIMDSVEVPEENVLPNVSSLAGPFGCLNTARYGITWGVLGAAEFCLHTARQYALDRIQFG 323
Query: 541 KPLAKNQLIQKKLADMLTEISIGLQACLRVGRLKDEGLVTPEMISIIKRNSCGKALECAR 720
PLA+NQL+QKKLADMLTEI++GL ACL++GRLKD+ TPEM+S++KRN+CGKAL+ AR
Sbjct: 324 VPLARNQLVQKKLADMLTEITLGLHACLQLGRLKDQDKATPEMVSMLKRNNCGKALDIAR 383
Query: 721 MARDML 738
ARD+L
Sbjct: 384 QARDIL 389
Score = 31.2 bits (69), Expect = 3.4
Identities = 13/16 (81%), Positives = 14/16 (87%)
Frame = +2
Query: 743 NGISDEYHVIRHLLIL 790
NGISDEYHVIRH + L
Sbjct: 392 NGISDEYHVIRHAMNL 407
>sp|Q92947|GCDH_HUMAN Glutaryl-CoA dehydrogenase, mitochondrial precursor (GCD)
Length = 438
Score = 348 bits (893), Expect = 1e-95
Identities = 165/246 (67%), Positives = 200/246 (81%)
Frame = +1
Query: 1 SSLVMWPINEYGTQTQKDKFLPKLATGHLIGCFGLTEPNHGSNPGGMETRAKYNEKSKCY 180
SSLVM PI YG++ Q+ K+LP+LA G L+GCFGLTEPN GS+P METRA YN +K Y
Sbjct: 145 SSLVMHPIYAYGSEEQRQKYLPQLAKGELLGCFGLTEPNSGSDPSSMETRAHYNSSNKSY 204
Query: 181 VLNGSKTWITNSPIADVFIIWAKSDVDNKIRGFILERGMKGLSTPVIEGKFSLRASITGQ 360
LNG+KTWITNSP+AD+F++WA+ + D IRGF+LE+GM+GLS P I+GKFSLRAS TG
Sbjct: 205 TLNGTKTWITNSPMADLFVVWARCE-DGCIRGFLLEKGMRGLSAPRIQGKFSLRASATGM 263
Query: 361 ISMEDVEVPADNMFPKITGLQGPFGCLNNARYGIGWGTLGAAEFCLETARNYTLDRNQFS 540
I M+ VEVP +N+ P + L GPFGCLNNARYGI WG LGA+EFCL TAR Y LDR QF
Sbjct: 264 IIMDGVEVPEENVLPGASSLGGPFGCLNNARYGIAWGVLGASEFCLHTARQYALDRMQFG 323
Query: 541 KPLAKNQLIQKKLADMLTEISIGLQACLRVGRLKDEGLVTPEMISIIKRNSCGKALECAR 720
PLA+NQLIQKKLADMLTEI++GL ACL++GRLKD+ PEM+S++KRN+CGKAL+ AR
Sbjct: 324 VPLARNQLIQKKLADMLTEITLGLHACLQLGRLKDQDKAAPEMVSLLKRNNCGKALDIAR 383
Query: 721 MARDML 738
ARDML
Sbjct: 384 QARDML 389
Score = 31.2 bits (69), Expect = 3.4
Identities = 13/16 (81%), Positives = 14/16 (87%)
Frame = +2
Query: 743 NGISDEYHVIRHLLIL 790
NGISDEYHVIRH + L
Sbjct: 392 NGISDEYHVIRHAMNL 407
>sp|Q8HXX8|GCDH_MACFA Glutaryl-CoA dehydrogenase, mitochondrial precursor (GCD)
Length = 438
Score = 347 bits (889), Expect = 3e-95
Identities = 163/246 (66%), Positives = 199/246 (80%)
Frame = +1
Query: 1 SSLVMWPINEYGTQTQKDKFLPKLATGHLIGCFGLTEPNHGSNPGGMETRAKYNEKSKCY 180
S LVM PI YG++ Q+ K+LP+LA G L+GCFGLTEPN GS+P METRA+YN +K Y
Sbjct: 145 SPLVMHPIYAYGSEEQRQKYLPRLAKGELLGCFGLTEPNSGSDPSSMETRARYNSSNKSY 204
Query: 181 VLNGSKTWITNSPIADVFIIWAKSDVDNKIRGFILERGMKGLSTPVIEGKFSLRASITGQ 360
LNG+KTWITNSP+AD+F++WA+ + D +IRGF+LE+GM+GLS P I+GKFSLRAS TG
Sbjct: 205 TLNGTKTWITNSPMADLFVVWARCE-DGRIRGFLLEKGMRGLSAPRIQGKFSLRASATGM 263
Query: 361 ISMEDVEVPADNMFPKITGLQGPFGCLNNARYGIGWGTLGAAEFCLETARNYTLDRNQFS 540
I M+ VEVP +NM P + L G FGCLNN RYGI WG LGA+EFCL TAR Y LDR QF
Sbjct: 264 IIMDGVEVPEENMLPGASSLGGSFGCLNNGRYGIAWGVLGASEFCLHTARQYALDRMQFG 323
Query: 541 KPLAKNQLIQKKLADMLTEISIGLQACLRVGRLKDEGLVTPEMISIIKRNSCGKALECAR 720
PLA+NQLIQKKLADMLTEI++GL ACL++GRLKD+ PEM+S++KRN+CGKAL+ AR
Sbjct: 324 VPLARNQLIQKKLADMLTEITLGLHACLQLGRLKDQDKAAPEMVSLLKRNNCGKALDIAR 383
Query: 721 MARDML 738
ARDML
Sbjct: 384 QARDML 389
Score = 31.2 bits (69), Expect = 3.4
Identities = 13/16 (81%), Positives = 14/16 (87%)
Frame = +2
Query: 743 NGISDEYHVIRHLLIL 790
NGISDEYHVIRH + L
Sbjct: 392 NGISDEYHVIRHAMNL 407
>sp|Q96329|ACOX4_ARATH Acyl-coenzyme A oxidase 4, peroxisomal (AOX 4) (Short-chain
acyl-CoA oxidase) (SAOX) (AtCX4) (G6p) (AtG6)
Length = 436
Score = 140 bits (352), Expect = 5e-33
Identities = 85/246 (34%), Positives = 128/246 (52%)
Frame = +1
Query: 1 SSLVMWPINEYGTQTQKDKFLPKLATGHLIGCFGLTEPNHGSNPGGMETRAKYNEKSKCY 180
SSL M I G++ QK+K+LP LA + + C+ LTEP++GS+ G+ T A E +
Sbjct: 140 SSLGMLTIALCGSEAQKEKYLPSLAQLNTVACWALTEPDNGSDASGLGTTATKVEGG--W 197
Query: 181 VLNGSKTWITNSPIADVFIIWAKSDVDNKIRGFILERGMKGLSTPVIEGKFSLRASITGQ 360
+NG K WI NS AD+ II+A++ N+I GFI+++ GL I K LR G
Sbjct: 198 KINGQKRWIGNSTFADLLIIFARNTTTNQINGFIVKKDAPGLKATKIPNKIGLRMVQNGD 257
Query: 361 ISMEDVEVPADNMFPKITGLQGPFGCLNNARYGIGWGTLGAAEFCLETARNYTLDRNQFS 540
I +++V VP ++ P + Q L +R + W +G + + Y +R QF
Sbjct: 258 ILLQNVFVPDEDRLPGVNSFQDTSKVLAVSRVMVAWQPIGISMGIYDMCHRYLKERKQFG 317
Query: 541 KPLAKNQLIQKKLADMLTEISIGLQACLRVGRLKDEGLVTPEMISIIKRNSCGKALECAR 720
PLA QL Q+KL ML + R+ +L + G +TP S+ K KA E A
Sbjct: 318 APLAAFQLNQQKLVQMLGNVQAMFLMGWRLCKLYETGQMTPGQASLGKAWISSKARETAS 377
Query: 721 MARDML 738
+ R++L
Sbjct: 378 LGRELL 383
>sp|Q06319|ACDS_MEGEL Acyl-CoA dehydrogenase, short-chain specific (SCAD) (Butyryl-CoA
dehydrogenase) (BCAD)
Length = 383
Score = 137 bits (344), Expect = 4e-32
Identities = 91/232 (39%), Positives = 122/232 (52%), Gaps = 4/232 (1%)
Frame = +1
Query: 4 SLVMWPINEYGTQTQKDKFLPKLATGHLIGCFGLTEPNHGSNPGGMETRAKYNEKSKCYV 183
SL PI ++GT+ QK+KFL L G +G FGLTEPN G++ G +T A N+ Y
Sbjct: 95 SLCANPIWQFGTEAQKEKFLVPLVEGTKLGAFGLTEPNAGTDASGQQTIATKNDDG-TYT 153
Query: 184 LNGSKTWITNSPIADVFIIWA---KSDVDNKIRGFILERGMKGLSTPVIEGKFSLRASIT 354
LNGSK +ITN AD++I++A KS ++ I FILE G G + E K + S T
Sbjct: 154 LNGSKIFITNGGAADIYIVFAMTDKSKGNHGITAFILEDGTPGFTYGKKEDKMGIHTSQT 213
Query: 355 GQISMEDVEVPADNMF-PKITGLQGPFGCLNNARYGIGWGTLGAAEFCLETARNYTLDRN 531
++ +DV+VPA+NM + G + L+ R G+ LG AE L A Y+ R
Sbjct: 214 MELVFQDVKVPAENMLGEEGKGFKIAMMTLDGGRIGVAAQALGIAEAALADAVEYSKQRV 273
Query: 532 QFSKPLAKNQLIQKKLADMLTEISIGLQACLRVGRLKDEGLVTPEMISIIKR 687
QF KPL K Q I KLADM +I + K EG +I KR
Sbjct: 274 QFGKPLCKFQSISFKLADMKMQIEAARNLVYKAACKKQEGKPFTVDAAIAKR 325
>sp|P52042|ACDS_CLOAB Acyl-CoA dehydrogenase, short-chain specific (SCAD) (Butyryl-CoA
dehydrogenase)
Length = 379
Score = 137 bits (344), Expect = 4e-32
Identities = 88/222 (39%), Positives = 118/222 (53%), Gaps = 4/222 (1%)
Frame = +1
Query: 1 SSLVMWPINEYGTQTQKDKFLPKLATGHLIGCFGLTEPNHGSNPGGMETRAKYNEKSKCY 180
+SL INE+GT+ QK K+L LA G IG +GLTEPN G++ G +T A + Y
Sbjct: 91 TSLCASLINEHGTEEQKQKYLVPLAKGEKIGAYGLTEPNAGTDSGAQQTVAVL--EGDHY 148
Query: 181 VLNGSKTWITNSPIADVFIIWAKSDVDNKIRG---FILERGMKGLSTPVIEGKFSLRASI 351
V+NGSK +ITN +AD F+I+A +D +G FI+E+G KG S +E K +RAS
Sbjct: 149 VINGSKIFITNGGVADTFVIFAMTDRTKGTKGISAFIIEKGFKGFSIGKVEQKLGIRASS 208
Query: 352 TGQISMEDVEVPADNMFPKI-TGLQGPFGCLNNARYGIGWGTLGAAEFCLETARNYTLDR 528
T ++ ED+ VP +NM K G L+ R GI LG AE AR Y +R
Sbjct: 209 TTELVFEDMIVPVENMIGKEGKGFPIAMKTLDGGRIGIAAQALGIAEGAFNEARAYMKER 268
Query: 529 NQFSKPLAKNQLIQKKLADMLTEISIGLQACLRVGRLKDEGL 654
QF + L K Q + +ADM I + LK GL
Sbjct: 269 KQFGRSLDKFQGLAWMMADMDVAIESARYLVYKAAYLKQAGL 310
>sp|P45867|ACDA_BACSU Acyl-CoA dehydrogenase
Length = 379
Score = 133 bits (335), Expect = 5e-31
Identities = 84/221 (38%), Positives = 120/221 (54%), Gaps = 4/221 (1%)
Frame = +1
Query: 4 SLVMWPINEYGTQTQKDKFLPKLATGHLIGCFGLTEPNHGSNPGGMETRAKYNEKSKCYV 183
SL WP+ +GT+ QK ++L +LA G IG F LTE GS+ G M+T A+ YV
Sbjct: 92 SLCSWPLFAFGTEEQKTEYLTQLALGEKIGAFALTEAGSGSDAGSMKTTAE--RIGDDYV 149
Query: 184 LNGSKTWITNSPIADVFIIWAKSDVDNKIRG---FILERGMKGLSTPVIEGKFSLRASIT 354
LNGSK +ITN +AD++I++A +D + K +G FI+E+ +G T E K +R+S T
Sbjct: 150 LNGSKVFITNGGVADIYIVFAVTDPEKKKKGVTAFIVEKDFEGFFTGKKEKKLGIRSSPT 209
Query: 355 GQISMEDVEVPAD-NMFPKITGLQGPFGCLNNARYGIGWGTLGAAEFCLETARNYTLDRN 531
+I ED VPA + + G + L+ R GI +G A+ L+ A Y +R
Sbjct: 210 TEIMFEDCVVPASKRLGEEGEGFKIAMKTLDGGRNGIAAQAVGIAQGALDAALQYAKERK 269
Query: 532 QFSKPLAKNQLIQKKLADMLTEISIGLQACLRVGRLKDEGL 654
QF K +A+ Q I KLADM T I + L+ GL
Sbjct: 270 QFGKSIAEQQGIAFKLADMATMIEASRLLTYQAAWLESSGL 310
>sp|Q9JHI5|IVD_MOUSE Isovaleryl-CoA dehydrogenase, mitochondrial precursor (IVD)
Length = 424
Score = 130 bits (328), Expect = 3e-30
Identities = 81/228 (35%), Positives = 124/228 (54%), Gaps = 6/228 (2%)
Frame = +1
Query: 1 SSLVMWPINEYGTQTQKDKFLPKLATGHLIGCFGLTEPNHGSNPGGMETRAKYNEKSKCY 180
S+L + I G + QK+K+LPKL +G IG ++EPN GS+ M+ +A+ +K Y
Sbjct: 131 SNLCVNQIVRNGNEAQKEKYLPKLISGEFIGALAMSEPNAGSDVVSMKLKAE--KKGDHY 188
Query: 181 VLNGSKTWITNSPIADVFIIWAKSDV-----DNKIRGFILERGMKGLSTPVIEGKFSLRA 345
VLNG+K WITN P AD+ +++AK+D+ I FI+E+GM G ST K +R
Sbjct: 189 VLNGNKFWITNGPDADILVVYAKTDLTAVPASRGITAFIVEKGMPGFSTSKKLDKLGMRG 248
Query: 346 SITGQISMEDVEVPADNMFPKIT-GLQGPFGCLNNARYGIGWGTLGAAEFCLETARNYTL 522
S T ++ ED +VPA N+ + + G+ L+ R + G LG + L+ Y
Sbjct: 249 SNTCELVFEDCKVPAANVLSQESKGVYVLMSGLDLERLVLAGGPLGIMQAVLDHTIPYLH 308
Query: 523 DRNQFSKPLAKNQLIQKKLADMLTEISIGLQACLRVGRLKDEGLVTPE 666
R F + + + QL+Q K+ADM T + Q V + DEG + P+
Sbjct: 309 VREAFGQKIGQFQLMQGKMADMYTRLMASRQYVYNVAKACDEGHIIPK 356
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 97,420,349
Number of Sequences: 369166
Number of extensions: 2045641
Number of successful extensions: 4591
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4338
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4487
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 7425705210
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)