Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_016_B10
(746 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q8PJ55|IF2_XANAC Translation initiation factor IF-2 35 0.28
sp|Q9NR82|CIQ5_HUMAN Potassium voltage-gated channel subfam... 34 0.48
sp|Q10021|RSP5_CAEEL Probable splicing factor, arginine/ser... 34 0.48
sp|P29966|MARCS_HUMAN Myristoylated alanine-rich C-kinase s... 33 0.62
sp|Q4P0G6|CWC21_USTMA Pre-mRNA splicing factor CWC21 33 0.81
sp|Q69154|IE63_MCMVS Transcriptional regulator IE63 homolog... 33 0.81
sp|Q6NV75|GP153_HUMAN Probable G-protein coupled receptor 1... 33 1.1
sp|Q08189|TGM3_MOUSE Protein-glutamine gamma-glutamyltransf... 32 1.8
sp|Q92738|US6NL_HUMAN USP6 N-terminal-like protein (Related... 32 2.4
sp|O14686|MLL2_HUMAN Myeloid/lymphoid or mixed-lineage leuk... 32 2.4
>sp|Q8PJ55|IF2_XANAC Translation initiation factor IF-2
Length = 904
Score = 34.7 bits (78), Expect = 0.28
Identities = 22/47 (46%), Positives = 26/47 (55%), Gaps = 3/47 (6%)
Frame = -2
Query: 160 PIPLADAPRHCRIAPSPCASAAR---KPLAAPRRTRHPHSSPLSPPA 29
P P+ADAP+ PS A AAR P +APR R +SP S PA
Sbjct: 186 PAPVADAPK-----PSAAAPAARLPSSPSSAPRAARPAGASPASRPA 227
>sp|Q9NR82|CIQ5_HUMAN Potassium voltage-gated channel subfamily KQT member 5
(Voltage-gated potassium channel subunit Kv7.5)
(Potassium channel alpha subunit KvLQT5) (KQT-like 5)
Length = 897
Score = 33.9 bits (76), Expect = 0.48
Identities = 27/87 (31%), Positives = 41/87 (47%)
Frame = +3
Query: 90 LRAADAQGDGAILQCRGASANGIGGSHCRLDRVGQRQESAFVPSGARIRLAEQIEHWRDS 269
L +A A+GDG +L A+ G GG R R G++ GAR+ L + + S
Sbjct: 13 LNSAAARGDGLLLLGTRAATLGGGGGGLRESRRGKQ--------GARMSLLGKPLSYTSS 64
Query: 270 RKCRRGFLSHRRFDWQRVHLLHGERCW 350
+ CRR + +RR ++L R W
Sbjct: 65 QSCRRN-VKYRRVQNYLYNVLERPRGW 90
>sp|Q10021|RSP5_CAEEL Probable splicing factor, arginine/serine-rich 5 (RNA-binding
protein srp-3) (CeSC35-2)
Length = 208
Score = 33.9 bits (76), Expect = 0.48
Identities = 33/108 (30%), Positives = 44/108 (40%)
Frame = -2
Query: 367 SRQPQRQHRSPCSK*TLCQSNRRCERNPRRHLRESRQCSICSARRILAPDGTKADSCRCP 188
SR P+R+ RSP RR R P R R SR +RR + +++ S
Sbjct: 84 SRSPRRRSRSP----------RRRSRTPPR--RRSRSRDRKRSRRSRSRSSSRSRSPVRE 131
Query: 187 TRSNRQCEPPIPLADAPRHCRIAPSPCASAARKPLAAPRRTRHPHSSP 44
+R + P P D R AS +R PL A R+R SP
Sbjct: 132 SRRRSESRSPSPKRDLKRE--------ASRSRSPLPAKDRSRTRSGSP 171
>sp|P29966|MARCS_HUMAN Myristoylated alanine-rich C-kinase substrate (MARCKS) (Protein
kinase C substrate, 80 kDa protein, light chain) (PKCSL)
(80K-L protein)
Length = 332
Score = 33.5 bits (75), Expect = 0.62
Identities = 20/63 (31%), Positives = 27/63 (42%)
Frame = -2
Query: 217 GTKADSCRCPTRSNRQCEPPIPLADAPRHCRIAPSPCASAARKPLAAPRRTRHPHSSPLS 38
G A +C P+ + P A + A P A+AA AAP + P SP +
Sbjct: 273 GASAAACEAPSAAG-------PGAPPEQEAAPAEEPAAAAASSACAAPSQEAQPECSPEA 325
Query: 37 PPA 29
PPA
Sbjct: 326 PPA 328
>sp|Q4P0G6|CWC21_USTMA Pre-mRNA splicing factor CWC21
Length = 348
Score = 33.1 bits (74), Expect = 0.81
Identities = 42/172 (24%), Positives = 65/172 (37%), Gaps = 1/172 (0%)
Frame = -2
Query: 535 RAHRWHTQRDACAQQISPARNKGDRDSVVLIDQVLTAICATD*QQPTDRL*R*NPLSRQP 356
R H+Q + + SP R + S ++ + PT R
Sbjct: 198 RCSSTHSQSTSSSSPSSPPRKRARSRSASQDSSARSSSSHASPRSPTPRT---------- 247
Query: 355 QRQHRSPCSK*TLCQSNRRCERNPRRHLRESRQCSICSARRILAPDGTKADSCRCPTRSN 176
H + S + +R R+P H R SR S +R +++ S +RS+
Sbjct: 248 -TSHVASYSSYSSRSRSRSRSRSPLSHSRSSRSRSRSRSR-----SRSRSRSPLSHSRSS 301
Query: 175 RQCEPPIPLADAPRHCRIAPSPCASA-ARKPLAAPRRTRHPHSSPLSPPARR 23
R + +P R +PS CAS+ +R P PRR +P PP RR
Sbjct: 302 R--------SRSPSRSR-SPSRCASSRSRSPAHRPRRHSSSRVNPPGPPPRR 344
>sp|Q69154|IE63_MCMVS Transcriptional regulator IE63 homolog (Protein UL69)
Length = 841
Score = 33.1 bits (74), Expect = 0.81
Identities = 22/85 (25%), Positives = 35/85 (41%), Gaps = 6/85 (7%)
Frame = -2
Query: 265 SRQCSICSARRILAPDGTKADSCRCPTRSNRQCEPPIPLADAPRHCRIAP--SPC----A 104
S+ S S+ + +G + DS Q +P ++ + + P SPC A
Sbjct: 567 SKSPSTVSSTTVHGQNGARGDSAPSRKSQQSQQQPETTSKESSKTAAMPPPPSPCSPSPA 626
Query: 103 SAARKPLAAPRRTRHPHSSPLSPPA 29
S R+P +P + PH P PA
Sbjct: 627 SRERRPSKSPSSSPRPHDPPSGEPA 651
>sp|Q6NV75|GP153_HUMAN Probable G-protein coupled receptor 153 (G-protein coupled receptor
PGR1)
Length = 609
Score = 32.7 bits (73), Expect = 1.1
Identities = 24/73 (32%), Positives = 32/73 (43%), Gaps = 3/73 (4%)
Frame = -2
Query: 244 SARRILAPDGTKADSCRCPTRSNRQCEPPIPLADAPRHCRI---APSPCASAARKPLAAP 74
SA L PD + C ++ R+ P P A A AP+P +SA R P P
Sbjct: 493 SASASLLPDAFALTAFECEPQALRRPPGPFPAAPAAPDGADPGEAPTPPSSAQRSP--GP 550
Query: 73 RRTRHPHSSPLSP 35
R + H H+ L P
Sbjct: 551 RPSAHSHAGSLRP 563
>sp|Q08189|TGM3_MOUSE Protein-glutamine gamma-glutamyltransferase E precursor (TGase E)
(TGE) (TG(E)) (Transglutaminase-3) [Contains:
Protein-glutamine gamma-glutamyltransferase E 50 kDa
noncatalytic chain; Protein-glutamine
gamma-glutamyltransferase E 27 kDa catalytic chain]
Length = 693
Score = 32.0 bits (71), Expect = 1.8
Identities = 19/42 (45%), Positives = 20/42 (47%)
Frame = +3
Query: 471 LLRAGEICCAHASRCVCHLWARGSWSRITLNPHPDRSGTVQL 596
LL G C ASR +CH SRI P RSGT QL
Sbjct: 630 LLVEGSGCSVAASRLMCHPCVPKEKSRIRFEIFPTRSGTKQL 671
>sp|Q92738|US6NL_HUMAN USP6 N-terminal-like protein (Related to the N terminus of tre)
(RN-tre)
Length = 828
Score = 31.6 bits (70), Expect = 2.4
Identities = 30/113 (26%), Positives = 40/113 (35%)
Frame = -2
Query: 352 RQHRSPCSK*TLCQSNRRCERNPRRHLRESRQCSICSARRILAPDGTKADSCRCPTRSNR 173
R+H P S + + + P H R Q DG P+ SN
Sbjct: 587 RKHAEPSSSPSKVSNKFTFKVQPPSHARYPSQL-----------DGEARGLAHPPSYSN- 634
Query: 172 QCEPPIPLADAPRHCRIAPSPCASAARKPLAAPRRTRHPHSSPLSPPARRNSS 14
PP+ ++P+H A S AS P +R PH S LS A S
Sbjct: 635 ---PPVYHGNSPKHFPTANSSFASPQFSPGTQLNPSRRPHGSTLSVSASPEKS 684
>sp|O14686|MLL2_HUMAN Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related
protein)
Length = 5262
Score = 31.6 bits (70), Expect = 2.4
Identities = 18/55 (32%), Positives = 25/55 (45%), Gaps = 2/55 (3%)
Frame = -2
Query: 190 PTRSNRQCEPP--IPLADAPRHCRIAPSPCASAARKPLAAPRRTRHPHSSPLSPP 32
P ++R PP P++ P ++P P AS P + P SPLSPP
Sbjct: 566 PPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPP 620
Score = 30.8 bits (68), Expect = 4.0
Identities = 18/56 (32%), Positives = 25/56 (44%), Gaps = 2/56 (3%)
Frame = -2
Query: 190 PTRSNRQCEPP--IPLADAPRHCRIAPSPCASAARKPLAAPRRTRHPHSSPLSPPA 29
P ++R PP P++ P ++P P S R + P SPLSPPA
Sbjct: 620 PPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPA 675
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 90,835,019
Number of Sequences: 369166
Number of extensions: 1980298
Number of successful extensions: 7547
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 6826
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 7508
length of database: 68,354,980
effective HSP length: 108
effective length of database: 48,403,600
effective search space used: 6776504000
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)