Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_015_P20
(733 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q99460|PSD1_HUMAN 26S proteasome non-ATPase regulatory s... 129 1e-29
sp|O88761|PSD1_RAT 26S proteasome non-ATPase regulatory sub... 129 1e-29
sp|Q9V3P6|PSD1_DROME 26S proteasome non-ATPase regulatory s... 81 3e-15
sp|O74762|RPN2_SCHPO 26S proteasome regulatory subunit rpn2 72 2e-12
sp|Q6FIP2|RPN2_CANGA 26S proteasome regulatory subunit RPN2 70 6e-12
sp|Q75CF3|RPN2_ASHGO 26S proteasome regulatory subunit RPN2 69 1e-11
sp|Q18115|PSD1_CAEEL 26S proteasome non-ATPase regulatory s... 67 4e-11
sp|P32565|RPN2_YEAST 26S proteasome regulatory subunit RPN2 63 9e-10
sp|P42527|KMHA_DICDI Myosin heavy chain kinase A (MHCK A) 30 6.6
sp|Q5RC06|CTNL1_PONPY Alpha-catulin (Catenin alpha-like pro... 30 8.6
>sp|Q99460|PSD1_HUMAN 26S proteasome non-ATPase regulatory subunit 1 (26S proteasome
regulatory subunit RPN2) (26S proteasome regulatory
subunit S1) (26S proteasome subunit p112)
Length = 953
Score = 129 bits (323), Expect = 1e-29
Identities = 75/174 (43%), Positives = 100/174 (57%), Gaps = 3/174 (1%)
Frame = +1
Query: 1 FQNYWFWYPLTNFISLAFTLTSVIVLNKELKMPKLEIKSKAKPSTFAYPDPIQIXXXXXX 180
F +WFW+PL++F+SLA+T T VI LNK+LKMPK++ KS KPSTFAYP P+++
Sbjct: 766 FTQFWFWFPLSHFLSLAYTPTCVIGLNKDLKMPKVQYKSNCKPSTFAYPAPLEVPKEKEK 825
Query: 181 XXVETAVLSVXXXXXXXXXXXXXXXXXXEPMVVDTPTKLPE---KNDPELDFAILTNPAR 351
V TAVLS+ E M VD K E K +PE +F +L NPAR
Sbjct: 826 EKVSTAVLSI--TAKAKKKEKEKEKKEEEKMEVDEAEKKEEKEKKKEPEPNFQLLDNPAR 883
Query: 352 VMPSQLRVIELSQIDTSGELRRYNPIKGIEHGGILVARDSQPNKPSDIVETVKP 513
VMP+QL+V+ T E RY P K + GGI++ +D+ DI E V+P
Sbjct: 884 VMPAQLKVL------TMPETCRYQPFKPLSIGGIIILKDTS----EDIEELVEP 927
>sp|O88761|PSD1_RAT 26S proteasome non-ATPase regulatory subunit 1 (26S proteasome
regulatory subunit RPN2) (26S proteasome regulatory
subunit S1) (26S proteasome subunit p112)
Length = 953
Score = 129 bits (323), Expect = 1e-29
Identities = 73/174 (41%), Positives = 101/174 (58%), Gaps = 3/174 (1%)
Frame = +1
Query: 1 FQNYWFWYPLTNFISLAFTLTSVIVLNKELKMPKLEIKSKAKPSTFAYPDPIQIXXXXXX 180
F +WFW+PL++F+SLA+T T +I LNK+LKMPK++ KS KPSTFAYP P+++
Sbjct: 766 FTQFWFWFPLSHFLSLAYTPTCIIGLNKDLKMPKVQYKSNCKPSTFAYPAPLEVPKEKEK 825
Query: 181 XXVETAVLSVXXXXXXXXXXXXXXXXXXEPMVVDTPTKLPE---KNDPELDFAILTNPAR 351
V TAVLS+ E M VD K E K +PE +F +L NPAR
Sbjct: 826 EKVSTAVLSI--TAKAKKKEKEKEKKEEEKMEVDEAEKKEEKEKKKEPEPNFQLLDNPAR 883
Query: 352 VMPSQLRVIELSQIDTSGELRRYNPIKGIEHGGILVARDSQPNKPSDIVETVKP 513
VMP+QL+V+ ++ E RY P K + GGI++ +D+ DI E V+P
Sbjct: 884 VMPAQLKVLSMT------ETCRYQPFKPLSIGGIIILKDTS----EDIEELVEP 927
>sp|Q9V3P6|PSD1_DROME 26S proteasome non-ATPase regulatory subunit 1 (26S proteasome
regulatory subunit RPN2) (26S proteasome regulatory
complex subunit p110)
Length = 1020
Score = 80.9 bits (198), Expect = 3e-15
Identities = 38/70 (54%), Positives = 48/70 (68%)
Frame = +1
Query: 1 FQNYWFWYPLTNFISLAFTLTSVIVLNKELKMPKLEIKSKAKPSTFAYPDPIQIXXXXXX 180
F YW+W+PL + +SLAFT T VI LN +LKMPK+E KS AKPS +AYP P++
Sbjct: 782 FTQYWYWFPLAHTLSLAFTPTCVIGLNSDLKMPKMEYKSAAKPSLYAYPAPLEEKKSEER 841
Query: 181 XXVETAVLSV 210
V TAVLS+
Sbjct: 842 EKVATAVLSI 851
Score = 43.9 bits (102), Expect = 4e-04
Identities = 28/69 (40%), Positives = 40/69 (57%)
Frame = +1
Query: 301 EKNDPELDFAILTNPARVMPSQLRVIELSQIDTSGELRRYNPIKGIEHGGILVARDSQPN 480
EK +PE IL NPARV+ QL+V LS ID + Y P+K + GGI+V + +
Sbjct: 934 EKKEPEPTSEILQNPARVLRQQLKV--LSVIDG----QSYEPLKDVTIGGIIVFQHTGKA 987
Query: 481 KPSDIVETV 507
+ ++VE V
Sbjct: 988 EDQELVEPV 996
>sp|O74762|RPN2_SCHPO 26S proteasome regulatory subunit rpn2
Length = 965
Score = 71.6 bits (174), Expect = 2e-12
Identities = 55/191 (28%), Positives = 84/191 (43%), Gaps = 24/191 (12%)
Frame = +1
Query: 1 FQNYWFWYPLTNFISLAFTLTSVIVLNKELKMPKLEIKSKAKPSTFAYPDPIQIXXXXXX 180
F YW+W+PLT+F+SL+F+ T++I L+K L PK S +P FAYP
Sbjct: 749 FLQYWYWFPLTHFMSLSFSPTALIGLDKNLNAPKFSFISNVRPKLFAYPPKSVQPTAKTV 808
Query: 181 XXVETAVLS----VXXXXXXXXXXXXXXXXXXEPMVVD---------TPTKLPEKNDPEL 321
VETAVLS + M +D TP ++ E+ ++
Sbjct: 809 QKVETAVLSTTVKAQARAKRAEREKASKGSNDDEMKIDKKTTEEKEATPMEMDEEKSQDI 868
Query: 322 DF-----------AILTNPARVMPSQLRVIELSQIDTSGELRRYNPIKGIEHGGILVARD 468
L N RV+P+QL I + +G RY P++ GG+L+ D
Sbjct: 869 SINGNSKKEEPKSETLENFTRVVPAQLPYI---SFNLNG---RYYPVRKFT-GGVLMLID 921
Query: 469 SQPNKPSDIVE 501
+ +K D++E
Sbjct: 922 RESDKAPDLIE 932
>sp|Q6FIP2|RPN2_CANGA 26S proteasome regulatory subunit RPN2
Length = 941
Score = 70.1 bits (170), Expect = 6e-12
Identities = 48/193 (24%), Positives = 91/193 (47%), Gaps = 21/193 (10%)
Frame = +1
Query: 1 FQNYWFWYPLTNFISLAFTLTSVI-VLNKELKMPKLEIKSKAKPSTFAYPDPIQIXXXXX 177
F +W+W+P+ +F+SL+FT T+++ V +L +PK ++ A+ F+YP +
Sbjct: 733 FTQFWYWFPMAHFLSLSFTPTTIVGVRGSDLNIPKFDMNCYAREDVFSYPKMFEESADKE 792
Query: 178 XXXVETAVLSVXXXXXXXXXXXXXXXXXXE----PMVVDTPTKLPEKND------PELDF 327
V TA+LS E D + +K+D E DF
Sbjct: 793 VEKVATAILSTTARAKARAKKTKKEKDTNEDDKKKKEKDLKKEETKKDDAKKESEAEEDF 852
Query: 328 ---------AILTNPARVMPSQLRVIELSQIDTSGELRRYNPIKGIE-HGGILVARDSQP 477
+ N +RV+P QL+ ++ + + R+ P++ + G++V +D++P
Sbjct: 853 NKNRYSSKPYKIENMSRVLPQQLKYVQFIKEE------RFTPVRKFKGTNGVVVLKDNKP 906
Query: 478 NKPSDIVETVKPS 516
++P+ I+ETV+ S
Sbjct: 907 SEPASIIETVRQS 919
>sp|Q75CF3|RPN2_ASHGO 26S proteasome regulatory subunit RPN2
Length = 930
Score = 68.9 bits (167), Expect = 1e-11
Identities = 50/188 (26%), Positives = 86/188 (45%), Gaps = 18/188 (9%)
Frame = +1
Query: 1 FQNYWFWYPLTNFISLAFTLTSVI-VLNKELKMPKLEIKSKAKPSTFAYPDPIQIXXXXX 177
F +W+W+PL +F+SL+FT T+ I V + +LK+PK K F YP +
Sbjct: 728 FTQFWYWFPLAHFLSLSFTPTTTIGVRSHDLKIPKFSFHCHTKEGIFDYPPMFEEDIDKS 787
Query: 178 XXXVETAVLSV-----XXXXXXXXXXXXXXXXXXEPMVVDTPTKLPEKND---PELDFAI 333
V TAVLS E + V+ + +++D PE +F I
Sbjct: 788 IEKVATAVLSTTAKAKARAKKSKKDKAVEPDKSKEEIKVENEQRDKKEHDADVPEEEFKI 847
Query: 334 --------LTNPARVMPSQLRVIELSQIDTSGELRRYNPIKGIE-HGGILVARDSQPNKP 486
+ N RV+P QL+ I + + R+ P++ + G++V D P++P
Sbjct: 848 KYTSTYYKVENMTRVVPQQLKYIAFPKDE------RFTPVRKFKGSNGVIVLSDKTPDEP 901
Query: 487 SDIVETVK 510
++++TV+
Sbjct: 902 VEVIKTVR 909
>sp|Q18115|PSD1_CAEEL 26S proteasome non-ATPase regulatory subunit 1 (26S proteasome
regulatory subunit rpn-2)
Length = 965
Score = 67.4 bits (163), Expect = 4e-11
Identities = 53/199 (26%), Positives = 82/199 (41%), Gaps = 30/199 (15%)
Frame = +1
Query: 1 FQNYWFWYPLTNFISLAFTLTSVIVLNKELKMPKLEIKSKAKPSTFAYPDPIQIXXXXXX 180
F + WFW+ + FI+LA + ++++N+ LK+P L+ A FAYP +
Sbjct: 745 FLHGWFWHSMHFFIALAAKPSCLVMMNENLKIPVLDYICHANSQKFAYPPRAESKKDKDV 804
Query: 181 XXVETAVLSV---------------------------XXXXXXXXXXXXXXXXXXEPMVV 279
+ET VLS+ E M V
Sbjct: 805 KKIETVVLSITGKKNASKKLIAEEKKRREAAASASSAAAAPSSSSTSGTAPAAEDEKMEV 864
Query: 280 DTPTKLPEKNDPELD---FAILTNPARVMPSQLRVIELSQIDTSGELRRYNPIKGIEHGG 450
D P K ++ PE D L NPARV+P+Q ++I +S + R Y+P+K + GG
Sbjct: 865 DQPGKSKKEKAPEKDTKPLHRLQNPARVIPAQRQLISIS------DARAYSPMKPLYKGG 918
Query: 451 ILVARDSQPNKPSDIVETV 507
I+VA + +V V
Sbjct: 919 IIVADRVDKEREEKLVSEV 937
>sp|P32565|RPN2_YEAST 26S proteasome regulatory subunit RPN2
Length = 945
Score = 62.8 bits (151), Expect = 9e-10
Identities = 50/191 (26%), Positives = 81/191 (42%), Gaps = 21/191 (10%)
Frame = +1
Query: 1 FQNYWFWYPLTNFISLAFTLTSVI-VLNKELKMPKLEIKSKAKPSTFAYPDPIQIXXXXX 177
F +W+W+PL +F+SL+FT T+VI + + +PK ++ AK F+YP +
Sbjct: 736 FSQFWYWFPLAHFLSLSFTPTTVIGIRGSDQAIPKFQMNCYAKEDAFSYPRMYEEASGKE 795
Query: 178 XXXVETAVLSVXXXXXXXXXXXXXXXXXXEPM------------------VVDTPTKLPE 303
V TAVLS E + +T E
Sbjct: 796 VEKVATAVLSTTARAKARAKKTKKEKGPNEEEKKKEHEEKEKERETNKKGIKETKENDEE 855
Query: 304 --KNDPELDFAILTNPARVMPSQLRVIELSQIDTSGELRRYNPIKGIEHGGILVARDSQP 477
KN + N R++P Q R I + D +R++ KG + G++V RD +P
Sbjct: 856 FYKNKYSSKPYKVDNMTRILPQQSRYISFIKDDRFVPVRKF---KG--NNGVVVLRDREP 910
Query: 478 NKPSDIVETVK 510
+P ++ETV+
Sbjct: 911 KEPVALIETVR 921
>sp|P42527|KMHA_DICDI Myosin heavy chain kinase A (MHCK A)
Length = 1146
Score = 30.0 bits (66), Expect = 6.6
Identities = 14/63 (22%), Positives = 31/63 (49%)
Frame = +1
Query: 301 EKNDPELDFAILTNPARVMPSQLRVIELSQIDTSGELRRYNPIKGIEHGGILVARDSQPN 480
EK E + + + + ++++IE Q+DTS E+R+ ++ G ++ +
Sbjct: 284 EKKKSEQNQLLFDSKIESLKDKIKIIETQQLDTSSEVRKLK-LESTSSGNLMAGLNGTSG 342
Query: 481 KPS 489
+PS
Sbjct: 343 RPS 345
>sp|Q5RC06|CTNL1_PONPY Alpha-catulin (Catenin alpha-like protein 1) (Alpha-catenin-related
protein) (ACRP)
sp|Q9UBT7|CTNL1_HUMAN Alpha-catulin (Catenin alpha-like protein 1) (Alpha-catenin-related
protein) (ACRP)
Length = 734
Score = 29.6 bits (65), Expect = 8.6
Identities = 24/90 (26%), Positives = 41/90 (45%), Gaps = 2/90 (2%)
Frame = +2
Query: 392 SIHLEN*GDIILLKELNMEAFWLREI--ASQTSXXXXXXXXXXXCIETTKQMMMTGLLNR 565
S L++ ++LL E+N ++ ++TS CI T+ MM L+
Sbjct: 645 SKQLKDDDKLMLLLEINKLIPLCHQLQTVTKTSLQNKVFLKVDKCITKTRSMMAL-LVQL 703
Query: 566 KHLNHSCLKKIRMNQNRWIQVSMITTLLKK 655
L + LKK++M N W+ V+ T+ K
Sbjct: 704 LSLCYKLLKKLQMENNGWVSVTNKDTMDSK 733
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 67,838,584
Number of Sequences: 369166
Number of extensions: 1083764
Number of successful extensions: 2897
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 2817
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 2888
length of database: 68,354,980
effective HSP length: 108
effective length of database: 48,403,600
effective search space used: 6534486000
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)