Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= Dr_sW_015_O21 (771 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|Q63009|ANM1_RAT Protein arginine N-methyltransferase 1 394 e-109 sp|Q9JIF0|ANM1_MOUSE Protein arginine N-methyltransferase 1 394 e-109 sp|Q99873|ANM1_HUMAN Protein arginine N-methyltransferase 1... 394 e-109 sp|Q6PAK3|ANM4_MOUSE Protein arginine N-methyltransferase 4... 382 e-106 sp|Q9NR22|ANM4_HUMAN Protein arginine N-methyltransferase 4... 382 e-106 sp|Q9URX7|ANM1_SCHPO Probable protein arginine N-methyltran... 293 4e-79 sp|P38074|HMT1_YEAST HNRNP arginine N-methyltransferase (OD... 263 4e-70 sp|O60678|ANM3_HUMAN Protein arginine N-methyltransferase 3... 251 2e-66 sp|O70467|ANM3_RAT Protein arginine N-methyltransferase 3 (... 246 6e-65 sp|Q922H1|ANM3_MOUSE Protein arginine N-methyltransferase 3... 238 1e-62
>sp|Q63009|ANM1_RAT Protein arginine N-methyltransferase 1 Length = 353 Score = 394 bits (1013), Expect = e-109 Identities = 185/256 (72%), Positives = 220/256 (85%) Frame = +2 Query: 2 ASDMTSKDYYFDSYAHFGIHEEMLKDEVRTLTYRNALYHNKHXXXXXXXXXXGCGTGILC 181 A DMTSKDYYFDSYAHFGIHEEMLKDEVRTLTYRN+++HN+H G GTGILC Sbjct: 26 AEDMTSKDYYFDSYAHFGIHEEMLKDEVRTLTYRNSMFHNRHLFKDKVVLDVGSGTGILC 85 Query: 182 MFAVKAGAKKVIGIDCSNIIDYAKEIIKANKMEDKITLIKGKVEEVELPEDVLKVDIIIS 361 MFA KAGA+KVIGI+CS+I DYA +I+KANK++ +T+IKGKVEEVELP V KVDIIIS Sbjct: 86 MFAAKAGARKVIGIECSSISDYAVKIVKANKLDHVVTIIKGKVEEVELP--VEKVDIIIS 143 Query: 362 EWMGYCLFYESMLNTVLFARDKWLKTGGIIMPDKATLHLCAIEDRQYKDEKINWWENVYG 541 EWMGYCLFYESMLNTVL ARDKWL G+I PD+ATL++ AIEDRQYKD KI+WWENVYG Sbjct: 144 EWMGYCLFYESMLNTVLHARDKWLAPDGLIFPDRATLYVTAIEDRQYKDYKIHWWENVYG 203 Query: 542 FDMSCIRKVAVSEPLVDVVNPNQIVSNFCIVKEVNMYEIKVEDLSFSSPFTLAVRKNDYI 721 FDMSCI+ VA+ EPLVDVV+P Q+V+N C++KEV++Y +KVEDL+F+SPF L V++NDY+ Sbjct: 204 FDMSCIKDVAIKEPLVDVVDPKQLVTNACLIKEVDIYTVKVEDLTFTSPFCLQVKRNDYV 263 Query: 722 HALVAFFNIDFTSSHK 769 HALVA+FNI+FT HK Sbjct: 264 HALVAYFNIEFTRCHK 279
>sp|Q9JIF0|ANM1_MOUSE Protein arginine N-methyltransferase 1 Length = 371 Score = 394 bits (1013), Expect = e-109 Identities = 185/256 (72%), Positives = 220/256 (85%) Frame = +2 Query: 2 ASDMTSKDYYFDSYAHFGIHEEMLKDEVRTLTYRNALYHNKHXXXXXXXXXXGCGTGILC 181 A DMTSKDYYFDSYAHFGIHEEMLKDEVRTLTYRN+++HN+H G GTGILC Sbjct: 44 AEDMTSKDYYFDSYAHFGIHEEMLKDEVRTLTYRNSMFHNRHLFKDKVVLDVGSGTGILC 103 Query: 182 MFAVKAGAKKVIGIDCSNIIDYAKEIIKANKMEDKITLIKGKVEEVELPEDVLKVDIIIS 361 MFA KAGA+KVIGI+CS+I DYA +I+KANK++ +T+IKGKVEEVELP V KVDIIIS Sbjct: 104 MFAAKAGARKVIGIECSSISDYAVKIVKANKLDHVVTIIKGKVEEVELP--VEKVDIIIS 161 Query: 362 EWMGYCLFYESMLNTVLFARDKWLKTGGIIMPDKATLHLCAIEDRQYKDEKINWWENVYG 541 EWMGYCLFYESMLNTVL ARDKWL G+I PD+ATL++ AIEDRQYKD KI+WWENVYG Sbjct: 162 EWMGYCLFYESMLNTVLHARDKWLAPDGLIFPDRATLYVTAIEDRQYKDYKIHWWENVYG 221 Query: 542 FDMSCIRKVAVSEPLVDVVNPNQIVSNFCIVKEVNMYEIKVEDLSFSSPFTLAVRKNDYI 721 FDMSCI+ VA+ EPLVDVV+P Q+V+N C++KEV++Y +KVEDL+F+SPF L V++NDY+ Sbjct: 222 FDMSCIKDVAIKEPLVDVVDPKQLVTNACLIKEVDIYTVKVEDLTFTSPFCLQVKRNDYV 281 Query: 722 HALVAFFNIDFTSSHK 769 HALVA+FNI+FT HK Sbjct: 282 HALVAYFNIEFTRCHK 297
>sp|Q99873|ANM1_HUMAN Protein arginine N-methyltransferase 1 (Interferon receptor 1-bound protein 4) Length = 361 Score = 394 bits (1012), Expect = e-109 Identities = 185/256 (72%), Positives = 220/256 (85%) Frame = +2 Query: 2 ASDMTSKDYYFDSYAHFGIHEEMLKDEVRTLTYRNALYHNKHXXXXXXXXXXGCGTGILC 181 A DMTSKDYYFDSYAHFGIHEEMLKDEVRTLTYRN+++HN+H G GTGILC Sbjct: 34 AEDMTSKDYYFDSYAHFGIHEEMLKDEVRTLTYRNSMFHNRHLFKDKVVLDVGSGTGILC 93 Query: 182 MFAVKAGAKKVIGIDCSNIIDYAKEIIKANKMEDKITLIKGKVEEVELPEDVLKVDIIIS 361 MFA KAGA+KVIGI CS+I DYA +I+KANK++ +T+IKGKVEEVELP V KVDIIIS Sbjct: 94 MFAAKAGARKVIGIVCSSISDYAVKIVKANKLDHVVTIIKGKVEEVELP--VEKVDIIIS 151 Query: 362 EWMGYCLFYESMLNTVLFARDKWLKTGGIIMPDKATLHLCAIEDRQYKDEKINWWENVYG 541 EWMGYCLFYESMLNTVL+ARDKWL G+I PD+ATL++ AIEDRQYKD KI+WWENVYG Sbjct: 152 EWMGYCLFYESMLNTVLYARDKWLAPDGLIFPDRATLYVTAIEDRQYKDYKIHWWENVYG 211 Query: 542 FDMSCIRKVAVSEPLVDVVNPNQIVSNFCIVKEVNMYEIKVEDLSFSSPFTLAVRKNDYI 721 FDMSCI+ VA+ EPLVDVV+P Q+V+N C++KEV++Y +KVEDL+F+SPF L V++NDY+ Sbjct: 212 FDMSCIKDVAIKEPLVDVVDPKQLVTNACLIKEVDIYTVKVEDLTFTSPFCLQVKRNDYV 271 Query: 722 HALVAFFNIDFTSSHK 769 HALVA+FNI+FT HK Sbjct: 272 HALVAYFNIEFTRCHK 287
>sp|Q6PAK3|ANM4_MOUSE Protein arginine N-methyltransferase 4 (Heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 4) Length = 394 Score = 382 bits (981), Expect = e-106 Identities = 177/254 (69%), Positives = 216/254 (85%) Frame = +2 Query: 8 DMTSKDYYFDSYAHFGIHEEMLKDEVRTLTYRNALYHNKHXXXXXXXXXXGCGTGILCMF 187 +MTS+DYYFDSYAHFGIHEEMLKDEVRTLTYRN++YHNKH G GTGIL MF Sbjct: 69 EMTSRDYYFDSYAHFGIHEEMLKDEVRTLTYRNSMYHNKHVFKDKVVLDVGSGTGILSMF 128 Query: 188 AVKAGAKKVIGIDCSNIIDYAKEIIKANKMEDKITLIKGKVEEVELPEDVLKVDIIISEW 367 A KAGAKKV GI+CS+I DY+++IIKAN +++ IT+ KGKVEEVELP V KVDIIISEW Sbjct: 129 AAKAGAKKVFGIECSSISDYSEKIIKANHLDNVITIFKGKVEEVELP--VEKVDIIISEW 186 Query: 368 MGYCLFYESMLNTVLFARDKWLKTGGIIMPDKATLHLCAIEDRQYKDEKINWWENVYGFD 547 MGYCLFYESMLNTV+FARDKWLK GG++ PD+A L++ AIEDRQYKD KI+WWENVYGFD Sbjct: 187 MGYCLFYESMLNTVIFARDKWLKPGGLMFPDRAALYVVAIEDRQYKDFKIHWWENVYGFD 246 Query: 548 MSCIRKVAVSEPLVDVVNPNQIVSNFCIVKEVNMYEIKVEDLSFSSPFTLAVRKNDYIHA 727 M+CIR VA+ EPLVD+V+P Q+V+N C++KEV++Y +K E+LSF+S F L +++NDY+HA Sbjct: 247 MTCIRDVAMKEPLVDIVDPKQVVTNACLIKEVDIYTVKTEELSFTSAFCLQIQRNDYVHA 306 Query: 728 LVAFFNIDFTSSHK 769 LV +FNI+FT HK Sbjct: 307 LVTYFNIEFTKCHK 320
>sp|Q9NR22|ANM4_HUMAN Protein arginine N-methyltransferase 4 (Heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 4) Length = 334 Score = 382 bits (980), Expect = e-106 Identities = 177/254 (69%), Positives = 216/254 (85%) Frame = +2 Query: 8 DMTSKDYYFDSYAHFGIHEEMLKDEVRTLTYRNALYHNKHXXXXXXXXXXGCGTGILCMF 187 +MTS+DYYFDSYAHFGIHEEMLKDEVRTLTYRN++YHNKH G GTGIL MF Sbjct: 9 EMTSRDYYFDSYAHFGIHEEMLKDEVRTLTYRNSMYHNKHVFKDKVVLDVGSGTGILSMF 68 Query: 188 AVKAGAKKVIGIDCSNIIDYAKEIIKANKMEDKITLIKGKVEEVELPEDVLKVDIIISEW 367 A KAGAKKV GI+CS+I DY+++IIKAN +++ IT+ KGKVEEVELP V KVDIIISEW Sbjct: 69 AAKAGAKKVFGIECSSISDYSEKIIKANHLDNIITIFKGKVEEVELP--VEKVDIIISEW 126 Query: 368 MGYCLFYESMLNTVLFARDKWLKTGGIIMPDKATLHLCAIEDRQYKDEKINWWENVYGFD 547 MGYCLFYESMLNTV+FARDKWLK GG++ PD+A L++ AIEDRQYKD KI+WWENVYGFD Sbjct: 127 MGYCLFYESMLNTVIFARDKWLKPGGLMFPDRAALYVVAIEDRQYKDFKIHWWENVYGFD 186 Query: 548 MSCIRKVAVSEPLVDVVNPNQIVSNFCIVKEVNMYEIKVEDLSFSSPFTLAVRKNDYIHA 727 M+CIR VA+ EPLVD+V+P Q+V+N C++KEV++Y +K E+LSF+S F L +++NDY+HA Sbjct: 187 MTCIRDVAMKEPLVDIVDPKQVVTNACLIKEVDIYTVKTEELSFTSAFCLQIQRNDYVHA 246 Query: 728 LVAFFNIDFTSSHK 769 LV +FNI+FT HK Sbjct: 247 LVTYFNIEFTKCHK 260
>sp|Q9URX7|ANM1_SCHPO Probable protein arginine N-methyltransferase Length = 339 Score = 293 bits (750), Expect = 4e-79 Identities = 138/255 (54%), Positives = 190/255 (74%) Frame = +2 Query: 5 SDMTSKDYYFDSYAHFGIHEEMLKDEVRTLTYRNALYHNKHXXXXXXXXXXGCGTGILCM 184 S +T+KDYYFDSY+H+GIHEEMLKD+VRTL+YR+A+ N H GCGTGIL M Sbjct: 11 SGLTAKDYYFDSYSHWGIHEEMLKDDVRTLSYRDAIMQNPHLFRDKIVLDVGCGTGILSM 70 Query: 185 FAVKAGAKKVIGIDCSNIIDYAKEIIKANKMEDKITLIKGKVEEVELPEDVLKVDIIISE 364 F +AGAK V G+D S II A +I++ NK+ D+ITLI+GK+EE++LP V KVDII+SE Sbjct: 71 FCARAGAKHVYGVDMSEIIHKAVQIVEVNKLSDRITLIQGKMEEIQLP--VEKVDIIVSE 128 Query: 365 WMGYCLFYESMLNTVLFARDKWLKTGGIIMPDKATLHLCAIEDRQYKDEKINWWENVYGF 544 WMGY L YESML+TVL ARD++L G++ PD+A + L AIED YK EKI +W++VYGF Sbjct: 129 WMGYFLLYESMLDTVLVARDRYLAPDGLLFPDRAQIQLAAIEDADYKSEKIGFWDDVYGF 188 Query: 545 DMSCIRKVAVSEPLVDVVNPNQIVSNFCIVKEVNMYEIKVEDLSFSSPFTLAVRKNDYIH 724 D S I+K EPLVD V+ + +N C++ ++++ +K EDL+FSSPF + +ND++H Sbjct: 189 DFSPIKKDVWKEPLVDTVDRIAVNTNSCVILDLDLKTVKKEDLAFSSPFEITATRNDFVH 248 Query: 725 ALVAFFNIDFTSSHK 769 A +A+F+I+F++ HK Sbjct: 249 AFLAWFDIEFSACHK 263
>sp|P38074|HMT1_YEAST HNRNP arginine N-methyltransferase (ODP1 protein) Length = 348 Score = 263 bits (672), Expect = 4e-70 Identities = 128/246 (52%), Positives = 174/246 (70%) Frame = +2 Query: 17 SKDYYFDSYAHFGIHEEMLKDEVRTLTYRNALYHNKHXXXXXXXXXXGCGTGILCMFAVK 196 S+ +YF+SY H+GIHEEML+D VRTL+YRNA+ NK GCGTGIL MFA K Sbjct: 19 SEQHYFNSYDHYGIHEEMLQDTVRTLSYRNAIIQNKDLFKDKIVLDVGCGTGILSMFAAK 78 Query: 197 AGAKKVIGIDCSNIIDYAKEIIKANKMEDKITLIKGKVEEVELPEDVLKVDIIISEWMGY 376 GAK VIG+D S+II+ AKE+++ N DKITL++GK+E+V LP KVDIIISEWMGY Sbjct: 79 HGAKHVIGVDMSSIIEMAKELVELNGFSDKITLLRGKLEDVHLPFP--KVDIIISEWMGY 136 Query: 377 CLFYESMLNTVLFARDKWLKTGGIIMPDKATLHLCAIEDRQYKDEKINWWENVYGFDMSC 556 L YESM++TVL+ARD +L GG+I PDK ++HL +ED QYKDEK+N+W++VYGFD S Sbjct: 137 FLLYESMMDTVLYARDHYLVEGGLIFPDKCSIHLAGLEDSQYKDEKLNYWQDVYGFDYSP 196 Query: 557 IRKVAVSEPLVDVVNPNQIVSNFCIVKEVNMYEIKVEDLSFSSPFTLAVRKNDYIHALVA 736 + + EP+VD V N + + + E ++ +K+ DL+F S F L ++ D I+ +V Sbjct: 197 FVPLVLHEPIVDTVERNNVNTTSDKLIEFDLNTVKISDLAFKSNFKLTAKRQDMINGIVT 256 Query: 737 FFNIDF 754 +F+I F Sbjct: 257 WFDIVF 262
>sp|O60678|ANM3_HUMAN Protein arginine N-methyltransferase 3 (Heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 3) Length = 531 Score = 251 bits (641), Expect = 2e-66 Identities = 120/242 (49%), Positives = 168/242 (69%) Frame = +2 Query: 29 YFDSYAHFGIHEEMLKDEVRTLTYRNALYHNKHXXXXXXXXXXGCGTGILCMFAVKAGAK 208 YF SY H+GIHEEMLKD++RT +YR+ +Y N H GCGTGIL MFA KAGAK Sbjct: 220 YFSSYGHYGIHEEMLKDKIRTESYRDFIYQNPHIFKDKVVLDVGCGTGILSMFAAKAGAK 279 Query: 209 KVIGIDCSNIIDYAKEIIKANKMEDKITLIKGKVEEVELPEDVLKVDIIISEWMGYCLFY 388 KV+G+D S I+ A +II+ NK+ED ITLIKGK+EEV LP V KVD+IISEWMGY L + Sbjct: 280 KVLGVDQSEILYQAMDIIRLNKLEDTITLIKGKIEEVHLP--VEKVDVIISEWMGYFLLF 337 Query: 389 ESMLNTVLFARDKWLKTGGIIMPDKATLHLCAIEDRQYKDEKINWWENVYGFDMSCIRKV 568 ESML++VL+A++K+L GG + PD T+ L A+ D ++I +W++VYGF MSC++K Sbjct: 338 ESMLDSVLYAKNKYLAKGGSVYPDICTISLVAVSDVNKHADRIAFWDDVYGFKMSCMKKA 397 Query: 569 AVSEPLVDVVNPNQIVSNFCIVKEVNMYEIKVEDLSFSSPFTLAVRKNDYIHALVAFFNI 748 + E +V+V++P ++S C +K ++ + + DL FSS FTL + + A+ +F+I Sbjct: 398 VIPEAVVEVLDPKTLISEPCGIKHIDCHTTSISDLEFSSDFTLKITRTSMCTAIAGYFDI 457 Query: 749 DF 754 F Sbjct: 458 YF 459
>sp|O70467|ANM3_RAT Protein arginine N-methyltransferase 3 (Heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 3) Length = 528 Score = 246 bits (627), Expect = 6e-65 Identities = 121/242 (50%), Positives = 165/242 (68%) Frame = +2 Query: 29 YFDSYAHFGIHEEMLKDEVRTLTYRNALYHNKHXXXXXXXXXXGCGTGILCMFAVKAGAK 208 YF SY H+GIHEEMLKD+VRT +YR+ +Y N H GCGTGIL MFA KAGAK Sbjct: 217 YFSSYGHYGIHEEMLKDKVRTESYRDFIYQNPHIFKDKVVLDVGCGTGILSMFAAKAGAK 276 Query: 209 KVIGIDCSNIIDYAKEIIKANKMEDKITLIKGKVEEVELPEDVLKVDIIISEWMGYCLFY 388 KVI +D S I+ A +II+ NK+ED I LIKGK+EEV LP V KVD+IISEWMGY L + Sbjct: 277 KVIAVDQSEILYQAMDIIRLNKLEDTIVLIKGKIEEVSLP--VEKVDVIISEWMGYFLLF 334 Query: 389 ESMLNTVLFARDKWLKTGGIIMPDKATLHLCAIEDRQYKDEKINWWENVYGFDMSCIRKV 568 ESML++VL+A+ K+L GG + PD T+ L A+ D ++I +W++VYGF+MSC++K Sbjct: 335 ESMLDSVLYAKSKYLAKGGSVYPDICTISLVAVSDVSKHADRIAFWDDVYGFNMSCMKKA 394 Query: 569 AVSEPLVDVVNPNQIVSNFCIVKEVNMYEIKVEDLSFSSPFTLAVRKNDYIHALVAFFNI 748 + E +V+VV+ ++S+ C +K ++ + + DL FSS FTL K A+ +F+I Sbjct: 395 VIPEAVVEVVDHKTLISDPCDIKHIDCHTTSISDLEFSSDFTLRTTKTAMCTAVAGYFDI 454 Query: 749 DF 754 F Sbjct: 455 YF 456
>sp|Q922H1|ANM3_MOUSE Protein arginine N-methyltransferase 3 (Heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 3) Length = 532 Score = 238 bits (608), Expect = 1e-62 Identities = 120/246 (48%), Positives = 164/246 (66%), Gaps = 4/246 (1%) Frame = +2 Query: 29 YFDSYAHFGIHEEMLKDEVRTLTYRNALYHNKHXXXXXXXXXXGCGTGILCMFAVKAGAK 208 YF SY H+GIHEEMLKD+VRT +YR+ +Y N H GCGTGIL MFA K GAK Sbjct: 217 YFSSYGHYGIHEEMLKDKVRTESYRDFIYQNPHIFKDKVVLDVGCGTGILSMFAAKVGAK 276 Query: 209 KVIGIDCSNIIDYAKEIIKANKMEDKITLIKGKVEEVELPEDVLKVDIIISEWMGYCLFY 388 KVI +D S I+ A +II+ NK+ED I LIKGK+EEV LP V KVD+IISEWMGY L + Sbjct: 277 KVIAVDQSEILYQAMDIIRLNKLEDTIVLIKGKIEEVSLP--VEKVDVIISEWMGYFLLF 334 Query: 389 ESMLNTVLFARDKWLKTGGIIMPDKATLHLCAIEDRQYKDEKINWWENVYGFDMSCIRKV 568 ESML++VL+A+ K+L GG + PD T+ L A+ D ++I +W++VYGF+MSC++K Sbjct: 335 ESMLDSVLYAKSKYLAKGGSVYPDICTISLVAVSDVSKHADRIAFWDDVYGFNMSCMKKA 394 Query: 569 AVSEPLVDVVNPNQIVSNFCIV----KEVNMYEIKVEDLSFSSPFTLAVRKNDYIHALVA 736 + E +V+VV+ ++S+ C + K ++ + + DL FSS FTL K A+ Sbjct: 395 VIPEAVVEVVDHKTLISDPCDIKMDGKHIDCHTTSISDLEFSSDFTLRTTKTAMCTAVAG 454 Query: 737 FFNIDF 754 +F+I F Sbjct: 455 YFDIYF 460
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 78,448,334 Number of Sequences: 369166 Number of extensions: 1456530 Number of successful extensions: 4127 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 3983 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 4103 length of database: 68,354,980 effective HSP length: 108 effective length of database: 48,403,600 effective search space used: 7163732800 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)