Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= Dr_sW_015_L15 (398 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|Q29466|VPP1_BOVIN Vacuolar proton translocating ATPase 1... 89 3e-18 sp|Q920R6|VPP4_MOUSE Vacuolar proton translocating ATPase 1... 87 1e-17 sp|Q5R422|VPP1_PONPY Vacuolar proton translocating ATPase 1... 86 2e-17 sp|Q93050|VPP1_HUMAN Vacuolar proton translocating ATPase 1... 86 2e-17 sp|Q9Z1G4|VPP1_MOUSE Vacuolar proton translocating ATPase 1... 86 3e-17 sp|P25286|VPP1_RAT Vacuolar proton translocating ATPase 116... 86 3e-17 sp|Q9HBG4|VPP4_HUMAN Vacuolar proton translocating ATPase 1... 86 3e-17 sp|Q13488|VPP3_HUMAN Vacuolar proton translocating ATPase 1... 84 8e-17 sp|O97681|VPP2_BOVIN Vacuolar proton translocating ATPase 1... 80 1e-15 sp|Q9Y487|VPP2_HUMAN Vacuolar proton translocating ATPase 1... 80 2e-15
>sp|Q29466|VPP1_BOVIN Vacuolar proton translocating ATPase 116 kDa subunit a isoform 1 (V-ATPase 116-kDa isoform a1) (Clathrin-coated vesicle/synaptic vesicle proton pump 116 kDa subunit) (Vacuolar proton pump subunit 1) (Vacuolar adenosine triphosphatase subunit Ac116) Length = 838 Score = 89.0 bits (219), Expect = 3e-18 Identities = 42/77 (54%), Positives = 53/77 (68%) Frame = +3 Query: 3 LSIGLKQDTLAGSIXXXXXXXXXXXXTIAVLLLMEGLSAFLHALRLHWVEFQNKFYKGEG 182 + IGLK +LAG + T+A+LL+MEGLSAFLHALRLHWVEFQNKFY G G Sbjct: 761 IHIGLKVKSLAGGLALFFIFAAFATLTVAILLIMEGLSAFLHALRLHWVEFQNKFYSGTG 820 Query: 183 YKFNPFNFKGVDDLSLD 233 +KF PF+F+ + + D Sbjct: 821 FKFLPFSFEHIREGKFD 837
>sp|Q920R6|VPP4_MOUSE Vacuolar proton translocating ATPase 116 kDa subunit a isoform 4 (V-ATPase 116-kDa isoform a4) (Vacuolar proton translocating ATPase 116 kDa subunit a kidney isoform) Length = 833 Score = 87.0 bits (214), Expect = 1e-17 Identities = 42/71 (59%), Positives = 51/71 (71%) Frame = +3 Query: 3 LSIGLKQDTLAGSIXXXXXXXXXXXXTIAVLLLMEGLSAFLHALRLHWVEFQNKFYKGEG 182 +SIGL+ AG + T+A+LL+MEGLSAFLHALRLHWVEFQNKFY+G G Sbjct: 756 MSIGLRLQGWAGLVGVFIIFAVFAVLTVAILLVMEGLSAFLHALRLHWVEFQNKFYEGAG 815 Query: 183 YKFNPFNFKGV 215 KF+PF+FK V Sbjct: 816 SKFSPFSFKHV 826
>sp|Q5R422|VPP1_PONPY Vacuolar proton translocating ATPase 116 kDa subunit a isoform 1 (V-ATPase 116-kDa isoform a1) Length = 837 Score = 86.3 bits (212), Expect = 2e-17 Identities = 40/71 (56%), Positives = 50/71 (70%) Frame = +3 Query: 3 LSIGLKQDTLAGSIXXXXXXXXXXXXTIAVLLLMEGLSAFLHALRLHWVEFQNKFYKGEG 182 + IGL +LAG + T+A+LL+MEGLSAFLHALRLHWVEFQNKFY G G Sbjct: 760 IHIGLSVKSLAGGLVLFFFFTAFATLTVAILLIMEGLSAFLHALRLHWVEFQNKFYSGTG 819 Query: 183 YKFNPFNFKGV 215 +KF PF+F+ + Sbjct: 820 FKFLPFSFEHI 830
>sp|Q93050|VPP1_HUMAN Vacuolar proton translocating ATPase 116 kDa subunit a isoform 1 (V-ATPase 116-kDa isoform a1) (Clathrin-coated vesicle/synaptic vesicle proton pump 116 kDa subunit) (Vacuolar proton pump subunit 1) (Vacuolar adenosine triphosphatase subunit Ac116) Length = 837 Score = 86.3 bits (212), Expect = 2e-17 Identities = 40/71 (56%), Positives = 50/71 (70%) Frame = +3 Query: 3 LSIGLKQDTLAGSIXXXXXXXXXXXXTIAVLLLMEGLSAFLHALRLHWVEFQNKFYKGEG 182 + IGL +LAG + T+A+LL+MEGLSAFLHALRLHWVEFQNKFY G G Sbjct: 760 IHIGLSVKSLAGGLVLFFFFTAFATLTVAILLIMEGLSAFLHALRLHWVEFQNKFYSGTG 819 Query: 183 YKFNPFNFKGV 215 +KF PF+F+ + Sbjct: 820 FKFLPFSFEHI 830
>sp|Q9Z1G4|VPP1_MOUSE Vacuolar proton translocating ATPase 116 kDa subunit a isoform 1 (V-ATPase 116-kDa isoform a1) (Clathrin-coated vesicle/synaptic vesicle proton pump 116 kDa subunit) (Vacuolar proton pump subunit 1) (Vacuolar adenosine triphosphatase subunit Ac116) Length = 839 Score = 85.9 bits (211), Expect = 3e-17 Identities = 41/77 (53%), Positives = 52/77 (67%) Frame = +3 Query: 3 LSIGLKQDTLAGSIXXXXXXXXXXXXTIAVLLLMEGLSAFLHALRLHWVEFQNKFYKGEG 182 + IGL +LAG + T+A+LL+MEGLSAFLHALRLHWVEFQNKFY G G Sbjct: 762 IHIGLHVRSLAGGLGLFFIFAAFATLTVAILLIMEGLSAFLHALRLHWVEFQNKFYTGTG 821 Query: 183 YKFNPFNFKGVDDLSLD 233 +KF PF+F+ + + D Sbjct: 822 FKFLPFSFEHIREGKFD 838
>sp|P25286|VPP1_RAT Vacuolar proton translocating ATPase 116 kDa subunit a isoform 1 (V-ATPase 116-kDa isoform a1) (Clathrin-coated vesicle/synaptic vesicle proton pump 116 kDa subunit) (Vacuolar proton pump subunit 1) (Vacuolar adenosine triphosphatase subunit Ac116) Length = 838 Score = 85.9 bits (211), Expect = 3e-17 Identities = 41/77 (53%), Positives = 52/77 (67%) Frame = +3 Query: 3 LSIGLKQDTLAGSIXXXXXXXXXXXXTIAVLLLMEGLSAFLHALRLHWVEFQNKFYKGEG 182 + IGL +LAG + T+A+LL+MEGLSAFLHALRLHWVEFQNKFY G G Sbjct: 761 IHIGLHVRSLAGGLGLFFIFAAFATLTVAILLIMEGLSAFLHALRLHWVEFQNKFYTGTG 820 Query: 183 YKFNPFNFKGVDDLSLD 233 +KF PF+F+ + + D Sbjct: 821 FKFLPFSFEHIREGKFD 837
>sp|Q9HBG4|VPP4_HUMAN Vacuolar proton translocating ATPase 116 kDa subunit a isoform 4 (V-ATPase 116-kDa isoform a4) (Vacuolar proton translocating ATPase 116 kDa subunit a kidney isoform) Length = 840 Score = 85.5 bits (210), Expect = 3e-17 Identities = 37/47 (78%), Positives = 44/47 (93%) Frame = +3 Query: 81 TIAVLLLMEGLSAFLHALRLHWVEFQNKFYKGEGYKFNPFNFKGVDD 221 T+A+LL+MEGLSAFLHALRLHWVEFQNKFY G+GYKF+PF+FK + D Sbjct: 789 TVAILLIMEGLSAFLHALRLHWVEFQNKFYVGDGYKFSPFSFKHILD 835
>sp|Q13488|VPP3_HUMAN Vacuolar proton translocating ATPase 116 kDa subunit a isoform 3 (V-ATPase 116-kDa isoform a3) (Osteoclastic proton pump 116 kDa subunit) (OC-116 kDa) (OC116) (T-cell immune regulator 1) (T cell immune response cDNA7 protein) (TIRC7) Length = 830 Score = 84.3 bits (207), Expect = 8e-17 Identities = 38/73 (52%), Positives = 48/73 (65%) Frame = +3 Query: 3 LSIGLKQDTLAGSIXXXXXXXXXXXXTIAVLLLMEGLSAFLHALRLHWVEFQNKFYKGEG 182 + +GL ++ ++ T+A+LL+MEGLSAFLHALRLHWVEFQNKFY G G Sbjct: 758 IGLGLGREVGVAAVVLVPIFAAFAVMTVAILLVMEGLSAFLHALRLHWVEFQNKFYSGTG 817 Query: 183 YKFNPFNFKGVDD 221 YK +PF F DD Sbjct: 818 YKLSPFTFAATDD 830
>sp|O97681|VPP2_BOVIN Vacuolar proton translocating ATPase 116 kDa subunit A isoform 2 (V-ATPase 116-kDa isoform a2) Length = 854 Score = 80.5 bits (197), Expect = 1e-15 Identities = 38/69 (55%), Positives = 47/69 (68%) Frame = +3 Query: 3 LSIGLKQDTLAGSIXXXXXXXXXXXXTIAVLLLMEGLSAFLHALRLHWVEFQNKFYKGEG 182 + +GL+ DT G + TI +LL+MEGLSAFLHA+RLHWVEFQNKFY G G Sbjct: 775 MHVGLRVDTAYGVLVLLPVIAFFAVLTIFILLIMEGLSAFLHAIRLHWVEFQNKFYVGAG 834 Query: 183 YKFNPFNFK 209 KF PF+F+ Sbjct: 835 TKFVPFSFR 843
>sp|Q9Y487|VPP2_HUMAN Vacuolar proton translocating ATPase 116 kDa subunit a isoform 2 (V-ATPase 116-kDa isoform a2) (TJ6) Length = 856 Score = 79.7 bits (195), Expect = 2e-15 Identities = 38/68 (55%), Positives = 46/68 (67%) Frame = +3 Query: 3 LSIGLKQDTLAGSIXXXXXXXXXXXXTIAVLLLMEGLSAFLHALRLHWVEFQNKFYKGEG 182 + +GL+ DT G + TI +LL+MEGLSAFLHA+RLHWVEFQNKFY G G Sbjct: 775 MRVGLRVDTTYGVLLLLPVIALFAVLTIFILLIMEGLSAFLHAIRLHWVEFQNKFYVGAG 834 Query: 183 YKFNPFNF 206 KF PF+F Sbjct: 835 TKFVPFSF 842
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 39,487,501 Number of Sequences: 369166 Number of extensions: 650625 Number of successful extensions: 1606 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 1585 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 1606 length of database: 68,354,980 effective HSP length: 98 effective length of database: 50,250,950 effective search space used: 1708532300 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)