Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_015_K11
(865 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|O97490|TRFM_RABIT Melanotransferrin precursor (Membrane-... 153 7e-37
sp|P08582|TRFM_HUMAN Melanotransferrin precursor (Melanoma-... 147 4e-35
sp|Q9R0R1|TRFM_MOUSE Melanotransferrin precursor (Membrane-... 143 7e-34
sp|P20233|TRFE_XENLA Serotransferrin precursor 135 2e-31
sp|P02787|TRFE_HUMAN Serotransferrin precursor (Transferrin... 134 4e-31
sp|Q02942|TRF_BLADI Transferrin precursor 132 1e-30
sp|Q29477|TRFL_CAPHI Lactotransferrin precursor (Lactoferrin) 127 3e-29
sp|P02788|TRFL_HUMAN Lactotransferrin precursor (Lactoferri... 126 7e-29
sp|Q921I1|TRFE_MOUSE Serotransferrin precursor (Transferrin... 126 9e-29
sp|P02789|TRFE_CHICK Ovotransferrin precursor (Conalbumin) ... 125 2e-28
>sp|O97490|TRFM_RABIT Melanotransferrin precursor (Membrane-bound transferrin-like protein
p97)
Length = 736
Score = 153 bits (386), Expect = 7e-37
Identities = 86/234 (36%), Positives = 131/234 (55%), Gaps = 7/234 (2%)
Frame = +3
Query: 3 SGWVIPVNIAMETVQFRVYSDNLVYSFSELIARSCIPGILSDDYNPSKKNPLNLCEICAA 182
+GW +PV + R + +++ + + SC+P N KK P +LC +C
Sbjct: 484 AGWDVPVGALIHWGYIRPRNCDVLTAVGQFFNASCVP------VNNPKKYPSSLCALCVG 537
Query: 183 G--GQDRCLPDSREQYYGDSGAFRCMLEN-GDVAFARHTTVHDNTDGRNPVDWARNRRSD 353
G+++C +S+E+YYGDSGAFRC++E GDVAF +HTT+ DNT+G NP WA + RS
Sbjct: 538 DEQGRNKCTGNSQERYYGDSGAFRCLVEGAGDVAFVKHTTIFDNTNGHNPEPWAAHLRSQ 597
Query: 354 DYEILCPDGTRVDTYSWQKCNLGKIPGNVIVTGGFKSQPQRN--EMWRLLRYAQEYFASD 527
DYE+LCP+G R + + + CNL +IP + ++ +P N ++ LL AQ+ F D
Sbjct: 598 DYELLCPNGARAEAHQFAACNLAQIPSHAVMV-----RPDTNIFTVYGLLDKAQDLFGDD 652
Query: 528 SN-NVFTMF-ASPYGRSDLMFSDSAVSLKPISPENQNYTMILDRSFARQVENLE 683
N N F MF +S Y DL+F D+ V P+ E Y L + +E ++
Sbjct: 653 HNKNGFKMFDSSSYHGRDLLFKDATVRAVPVG-ERTTYQDWLGPDYVAALEGMQ 705
Score = 134 bits (337), Expect = 3e-31
Identities = 78/229 (34%), Positives = 121/229 (52%), Gaps = 4/229 (1%)
Frame = +3
Query: 6 GWVIPVNIAMETVQFRVYSDNLVYSFSELIARSCIPGILSDDYNPSKKNPLNLCEICAA- 182
GW +PV +++ + V +++ + SE SC+PG Y+ S LC +C
Sbjct: 139 GWNVPVGYLVDSGRLSVMGCDVLKAVSEYFGGSCVPGAGETRYSES------LCRLCRGD 192
Query: 183 -GGQDRCLPDSREQYYGDSGAFRCMLEN-GDVAFARHTTVHDNTDGRNPVDWARNRRSDD 356
G+ C E+YY SGAFRC+ E GDVAF +H+TV +NTDGR W S D
Sbjct: 193 TSGEGVCDKSPLERYYDYSGAFRCLAEGAGDVAFVKHSTVLENTDGRTLPSWGHMLMSRD 252
Query: 357 YEILCPDGTRVDTYSWQKCNLGKIPGNVIVTGGFKSQPQRNEMWRLLRYAQEYFASDSNN 536
+E+LC DG+R WQ C+L ++P + +V ++ ++RLL Q F+ + ++
Sbjct: 253 FELLCRDGSRASVTEWQHCHLARVPAHAVVV---RADTDAGLIFRLLNEGQRLFSHEGSS 309
Query: 537 VFTMFAS-PYGRSDLMFSDSAVSLKPISPENQNYTMILDRSFARQVENL 680
F MF+S YG+ +L+F DS + L PI+ Q Y L + ++ L
Sbjct: 310 -FQMFSSEAYGQKNLLFKDSTLELVPIA--TQTYEAWLGPEYLHAMKGL 355
>sp|P08582|TRFM_HUMAN Melanotransferrin precursor (Melanoma-associated antigen p97) (CD228
antigen)
Length = 738
Score = 147 bits (371), Expect = 4e-35
Identities = 87/233 (37%), Positives = 128/233 (54%), Gaps = 7/233 (3%)
Frame = +3
Query: 3 SGWVIPVNIAMETVQFRVYSDNLVYSFSELIARSCIPGILSDDYNPSKKNPLNLCEICAA 182
+GW +PV ++ R +++ + SE SC+P N K P +LC +C
Sbjct: 484 AGWDVPVGALIQRGFIRPKDCDVLTAVSEFFNASCVP------VNNPKNYPSSLCALCVG 537
Query: 183 G--GQDRCLPDSREQYYGDSGAFRCMLEN-GDVAFARHTTVHDNTDGRNPVDWARNRRSD 353
G+++C+ +S+E+YYG GAFRC++EN GDVAF RHTTV DNT+G N WA RS+
Sbjct: 538 DEQGRNKCVGNSQERYYGYRGAFRCLVENAGDVAFVRHTTVFDNTNGHNSEPWAAELRSE 597
Query: 354 DYEILCPDGTRVDTYSWQKCNLGKIPGNVIVTGGFKSQPQRN--EMWRLLRYAQEYFASD 527
DYE+LCP+G R + + CNL +IP + ++ +P N ++ LL AQ+ F D
Sbjct: 598 DYELLCPNGARAEVSQFAACNLAQIPPHAVMV-----RPDTNIFTVYGLLDKAQDLFGDD 652
Query: 528 SN-NVFTMF-ASPYGRSDLMFSDSAVSLKPISPENQNYTMILDRSFARQVENL 680
N N F MF +S Y DL+F D+ V P+ E Y L + +E +
Sbjct: 653 HNKNGFKMFDSSNYHGQDLLFKDATVRAVPVG-EKTTYRGWLGLDYVAALEGM 704
Score = 137 bits (346), Expect = 3e-32
Identities = 78/229 (34%), Positives = 124/229 (54%), Gaps = 4/229 (1%)
Frame = +3
Query: 6 GWVIPVNIAMETVQFRVYSDNLVYSFSELIARSCIPGILSDDYNPSKKNPLNLCEICA-- 179
GW +PV +E+ + V +++ + S+ SC+PG Y+ S LC +C
Sbjct: 139 GWNVPVGYLVESGRLSVMGCDVLKAVSDYFGGSCVPGAGETSYSES------LCRLCRGD 192
Query: 180 AGGQDRCLPDSREQYYGDSGAFRCMLEN-GDVAFARHTTVHDNTDGRNPVDWARNRRSDD 356
+ G+ C E+YY SGAFRC+ E GDVAF +H+TV +NTDG+ W + S D
Sbjct: 193 SSGEGVCDKSPLERYYDYSGAFRCLAEGAGDVAFVKHSTVLENTDGKTLPSWGQALLSQD 252
Query: 357 YEILCPDGTRVDTYSWQKCNLGKIPGNVIVTGGFKSQPQRNEMWRLLRYAQEYFASDSNN 536
+E+LC DG+R D W++C+L ++P + +V ++ ++RLL Q F+ + ++
Sbjct: 253 FELLCRDGSRADVTEWRQCHLARVPAHAVVV---RADTDGGLIFRLLNEGQRLFSHEGSS 309
Query: 537 VFTMFAS-PYGRSDLMFSDSAVSLKPISPENQNYTMILDRSFARQVENL 680
F MF+S YG+ DL+F DS L PI+ Q Y L + ++ L
Sbjct: 310 -FQMFSSEAYGQKDLLFKDSTSELVPIA--TQTYEAWLGHEYLHAMKGL 355
>sp|Q9R0R1|TRFM_MOUSE Melanotransferrin precursor (Membrane-bound transferrin-like protein
p97) (MTf)
Length = 738
Score = 143 bits (360), Expect = 7e-34
Identities = 79/211 (37%), Positives = 121/211 (57%), Gaps = 7/211 (3%)
Frame = +3
Query: 3 SGWVIPVNIAMETVQFRVYSDNLVYSFSELIARSCIPGILSDDYNPSKKNPLNLCEICAA 182
+GW +P+ ++ R +++ + S+ SC+P N K P LC +C
Sbjct: 484 AGWEVPIGSLIQRGFIRPKDCDVLTAVSQFFNASCVP------VNNPKNYPSALCALCVG 537
Query: 183 G--GQDRCLPDSREQYYGDSGAFRCMLEN-GDVAFARHTTVHDNTDGRNPVDWARNRRSD 353
G+++C+ S+E+YYG SGAFRC++E+ GDVAF +HTTV +NT+G NP WA + R
Sbjct: 538 DEKGRNKCVGSSQERYYGYSGAFRCLVEHAGDVAFVKHTTVFENTNGHNPEPWASHLRWQ 597
Query: 354 DYEILCPDGTRVDTYSWQKCNLGKIPGNVIVTGGFKSQPQRN--EMWRLLRYAQEYFASD 527
DYE+LCP+G R + +Q CNL ++P + ++ +P N ++ LL AQ+ F D
Sbjct: 598 DYELLCPNGARAEVDQFQACNLAQMPSHAVMV-----RPDTNIFTVYGLLDKAQDLFGDD 652
Query: 528 SN-NVFTMF-ASPYGRSDLMFSDSAVSLKPI 614
N N F MF +S Y DL+F D+ V P+
Sbjct: 653 HNKNGFQMFDSSKYHSQDLLFKDATVRAVPV 683
Score = 133 bits (334), Expect = 7e-31
Identities = 75/229 (32%), Positives = 125/229 (54%), Gaps = 4/229 (1%)
Frame = +3
Query: 6 GWVIPVNIAMETVQFRVYSDNLVYSFSELIARSCIPGILSDDYNPSKKNPLNLCEICA-- 179
GW +PV +E+ V +++ + + SC+PG ++ S LC +C
Sbjct: 139 GWNVPVGYLVESGHLSVMGCDVLKAVGDYFGGSCVPGTGETSHSES------LCRLCRGD 192
Query: 180 AGGQDRCLPDSREQYYGDSGAFRCMLEN-GDVAFARHTTVHDNTDGRNPVDWARNRRSDD 356
+ G + C E+YY SGAFRC+ E GDVAF +H+TV +NTDG W ++ S+D
Sbjct: 193 SSGHNVCDKSPLERYYDYSGAFRCLAEGAGDVAFVKHSTVLENTDGNTLPSWGKSLMSED 252
Query: 357 YEILCPDGTRVDTYSWQKCNLGKIPGNVIVTGGFKSQPQRNEMWRLLRYAQEYFASDSNN 536
+++LC DG+R D W++C+L K+P + +V G +++LL Q F+ + ++
Sbjct: 253 FQLLCRDGSRADITEWRRCHLAKVPAHAVVVRG---DMDGGLIFQLLNEGQLLFSHEDSS 309
Query: 537 VFTMFAS-PYGRSDLMFSDSAVSLKPISPENQNYTMILDRSFARQVENL 680
F MF+S Y + +L+F DS + L PI+ QNY L + + + ++ L
Sbjct: 310 -FQMFSSKAYSQKNLLFKDSTLELVPIA--TQNYEAWLGQEYLQAMKGL 355
>sp|P20233|TRFE_XENLA Serotransferrin precursor
Length = 701
Score = 135 bits (339), Expect = 2e-31
Identities = 75/212 (35%), Positives = 116/212 (54%), Gaps = 8/212 (3%)
Frame = +3
Query: 3 SGWVIPVNIAMETVQFRVYSDNLVYSFSELIARSCIPGILSDDYNPSKKNPLNLCEICAA 182
+GW IPV + + S+ F+ + SC PG SD + NLC +C
Sbjct: 474 AGWNIPVGL--------ITSETANCDFASYVGESCAPG--SDVKS-------NLCALCIG 516
Query: 183 GGQD------RCLPDSREQYYGDSGAFRCMLENGDVAFARHTTVHDNTDGRNPVDWARNR 344
+ +C P + E YYG SGAFRC++E G V FA+HTTV +NTDG+NP WA++
Sbjct: 517 DPEKLSEREKKCSPSASEAYYGYSGAFRCLVEKGQVGFAKHTTVFENTDGKNPAGWAKDL 576
Query: 345 RSDDYEILCPDGTRVDTYSWQKCNLGKIPGNVIVTGGFKSQPQRNEMWRLLRYAQEYFAS 524
+S+D+E+LCPDG+R +++CNL ++P + +VT +R ++ +++ Q +
Sbjct: 577 KSEDFELLCPDGSRAPVTDYKRCNLAEVPAHAVVT----LPDKREQVAKIVVNQQSLYGR 632
Query: 525 D--SNNVFTMFASPYGRSDLMFSDSAVSLKPI 614
++F MF S G+ DL+F DS L I
Sbjct: 633 KGFQKDIFQMFQSTGGK-DLLFKDSTQCLLEI 663
Score = 92.8 bits (229), Expect = 1e-18
Identities = 65/231 (28%), Positives = 115/231 (49%), Gaps = 4/231 (1%)
Frame = +3
Query: 3 SGWVIPVNIAMETVQFRVY---SDNLVYSFSELIARSCIPGILSDDYNPSKKNPLNLCEI 173
+GW I + + +E + S+ + S+ SC+PG K P L ++
Sbjct: 142 AGWNIIIGLLLERKLLKWAGPDSETWRNAVSKFFKASCVPGA---------KEP-KLSQL 191
Query: 174 CAAGGQDRCLPDSREQYYGDSGAFRCMLEN-GDVAFARHTTVHDNTDGRNPVDWARNRRS 350
CA + +C + E YY +GAF+C+ ++ GDVAF + +TV P ++ +
Sbjct: 192 CAGIKEHKCSRSNNEPYYNYAGAFKCLQDDQGDVAFVKQSTV--------PEEFHK---- 239
Query: 351 DDYEILCPDGTRVDTYSWQKCNLGKIPGNVIVTGGFKSQPQRNEMWRLLRYAQEYFASDS 530
DYE+LCPD TR ++ CNL K+P + ++T G + ++ ++ + QE +
Sbjct: 240 -DYELLCPDNTRKSIKEYKNCNLAKVPAHAVLTRG-----RDDKSKDIIEFLQE---AQK 290
Query: 531 NNVFTMFASPYGRSDLMFSDSAVSLKPISPENQNYTMILDRSFARQVENLE 683
+F+SP DL+F DSAVSL P+ P + + + L + + ++ L+
Sbjct: 291 TQECKLFSSPVWGRDLIFKDSAVSLIPL-PSSMDSFLFLGADYFQCIQALK 340
>sp|P02787|TRFE_HUMAN Serotransferrin precursor (Transferrin) (Siderophilin) (Beta-1-metal
binding globulin)
Length = 698
Score = 134 bits (336), Expect = 4e-31
Identities = 79/229 (34%), Positives = 115/229 (50%), Gaps = 3/229 (1%)
Frame = +3
Query: 3 SGWVIPVNIAMETVQFRVYSDNLVYSFSELIARSCIPGILSDDYNPSKKNPLNLCEICAA 182
+GW IP+ + + F E + C PG SKK+ +LC++C
Sbjct: 477 AGWNIPMGLLYNKINH--------CRFDEFFSEGCAPG--------SKKDS-SLCKLCMG 519
Query: 183 GGQDRCLPDSREQYYGDSGAFRCMLENGDVAFARHTTVHDNTDGRNPVDWARNRRSDDYE 362
G + C P+++E YYG +GAFRC++E GDVAF +H TV NT G+NP WA+N DYE
Sbjct: 520 SGLNLCEPNNKEGYYGYTGAFRCLVEKGDVAFVKHQTVPQNTGGKNPDPWAKNLNEKDYE 579
Query: 363 ILCPDGTRVDTYSWQKCNLGKIPGNVIVTGGFKSQPQRNEMWRLLRYAQEYFAS---DSN 533
+LC DGTR + C+L + P + +VT + + + ++LR Q F S D +
Sbjct: 580 LLCLDGTRKPVEEYANCHLARAPNHAVVT----RKDKEACVHKILRQQQHLFGSNVTDCS 635
Query: 534 NVFTMFASPYGRSDLMFSDSAVSLKPISPENQNYTMILDRSFARQVENL 680
F +F S DL+F D V L + N Y L + + V NL
Sbjct: 636 GNFCLFRSE--TKDLLFRDDTVCLAKLHDRN-TYEKYLGEEYVKAVGNL 681
Score = 102 bits (253), Expect = 2e-21
Identities = 68/228 (29%), Positives = 110/228 (48%), Gaps = 2/228 (0%)
Frame = +3
Query: 3 SGWVIPVNIAM-ETVQFRVYSDNLVYSFSELIARSCIPGILSDDYNPSKKNPLNLCEICA 179
+GW IP+ + + + R + V +F + SC P D+ LC++C
Sbjct: 145 AGWNIPIGLLYCDLPEPRKPLEKAVANF---FSGSCAPCADGTDFP-------QLCQLCP 194
Query: 180 AGGQDRCLPDSREQYYGDSGAFRCMLEN-GDVAFARHTTVHDNTDGRNPVDWARNRRSDD 356
C + QY+G SGAF+C+ + GDVAF +H+T+ +N A D
Sbjct: 195 G-----CGCSTLNQYFGYSGAFKCLKDGAGDVAFVKHSTIFENL--------ANKADRDQ 241
Query: 357 YEILCPDGTRVDTYSWQKCNLGKIPGNVIVTGGFKSQPQRNEMWRLLRYAQEYFASDSNN 536
YE+LC D TR ++ C+L ++P + +V + + +W LL AQE+F D +
Sbjct: 242 YELLCLDNTRKPVDEYKDCHLAQVPSHTVVARSMGGK--EDLIWELLNQAQEHFGKDKSK 299
Query: 537 VFTMFASPYGRSDLMFSDSAVSLKPISPENQNYTMILDRSFARQVENL 680
F +F+SP+G+ DL+F DSA + P + M L + + NL
Sbjct: 300 EFQLFSSPHGK-DLLFKDSAHGFLKV-PPRMDAKMYLGYEYVTAIRNL 345
>sp|Q02942|TRF_BLADI Transferrin precursor
Length = 726
Score = 132 bits (333), Expect = 1e-30
Identities = 82/232 (35%), Positives = 124/232 (53%), Gaps = 16/232 (6%)
Frame = +3
Query: 3 SGWVIPVN--IAMETVQFRV--YSDNLVYSFSELIARSCIPGILSDDYNPSKKNPLNLCE 170
+GW +P+ ++ E + YS L FS SC+PG + NP+ +NP +LC
Sbjct: 489 AGWNVPLYTLLSKELISKNSCPYSSALSSYFS---GGSCVPGAQLPENNPANQNPDSLCS 545
Query: 171 ICAAGGQD--------RCLPDSREQYYGDSGAFRCMLEN-GDVAFARHTTVHDNTDGRNP 323
ICA G D +C + E ++G SGAFRC+ G VAF +HTTV +NTDG N
Sbjct: 546 ICA-GNLDAPNNDPAWKCSASNDESFFGYSGAFRCLASGEGQVAFVKHTTVPENTDGHNQ 604
Query: 324 VDWARNRRSDDYEILCPDGTRVDTYSWQKCNLGKIPGNVIVTGGFKSQPQRNEMWRLLRY 503
W RS+D+E+LC DG R + +C+L ++P +++VT K+ Q NE+ +
Sbjct: 605 AAWTAGLRSEDFELLCADGGRASINEYSRCHLAEVPPHMVVTSNDKTDIQLNEIRHAILA 664
Query: 504 AQEYFASDSNNVFTMFASPYGRSDLMFSDSAVSLKPI---SPENQNYTMILD 650
A + + S ++F +F G DL+F +SA L + SP Q Y+ IL+
Sbjct: 665 AGDLY-SRRPDLFKLFGDFGGTKDLLFKNSATGLLSVENGSPLMQRYSEILE 715
Score = 42.0 bits (97), Expect = 0.002
Identities = 35/125 (28%), Positives = 57/125 (45%), Gaps = 17/125 (13%)
Frame = +3
Query: 63 DNLVYSFSELIARSCIPGILSDDYNPSKKNPL-----NLCEICAAGGQDRCLPDSREQYY 227
+N +++ S L + +C+ G + D P++ L NLC +C + + D ++Y
Sbjct: 170 ENELHALSHLFSEACLVGKWAPD--PAQNQALKAKYPNLCALC----EHPEICDYPDKYS 223
Query: 228 GDSGAFRCMLEN-GDVAFARHTTVHDN-----------TDGRNPVDWARNRRSDDYEILC 371
G GA RC+ E+ G VA+ + V + G+NP DDY LC
Sbjct: 224 GYDGALRCLAEHGGQVAWTKVYYVKKHFGMAIGAGEAVPTGQNP---------DDYAYLC 274
Query: 372 PDGTR 386
PD T+
Sbjct: 275 PDATK 279
>sp|Q29477|TRFL_CAPHI Lactotransferrin precursor (Lactoferrin)
Length = 708
Score = 127 bits (320), Expect = 3e-29
Identities = 74/236 (31%), Positives = 122/236 (51%), Gaps = 1/236 (0%)
Frame = +3
Query: 3 SGWVIPVNIAMETVQFRVYSDNLVYSFSELIARSCIPGILSDDYNPSKKNPLNLCEICAA 182
+GW IPV I + + ++ L + + + SC+P + Y NLC++C
Sbjct: 142 AGWNIPVGILRPFLSWTESAEPLQGAVARFFSASCVPCVDGKAYP-------NLCQLCKG 194
Query: 183 GGQDRCLPDSREQYYGDSGAFRCMLEN-GDVAFARHTTVHDNTDGRNPVDWARNRRSDDY 359
G+++C S+E Y+G SGAF+C+ + GDVAF + TTV +N + D Y
Sbjct: 195 VGENKCACSSQEPYFGYSGAFKCLQDGAGDVAFVKETTVFENLPEKAD--------RDQY 246
Query: 360 EILCPDGTRVDTYSWQKCNLGKIPGNVIVTGGFKSQPQRNEMWRLLRYAQEYFASDSNNV 539
E+LC + TR ++++C+L ++P + +V + N +W LLR AQE F + +
Sbjct: 247 ELLCLNNTRAPVDAFKECHLAQVPSHAVVARSVDGK--ENLIWELLRKAQEKFGKNKSQS 304
Query: 540 FTMFASPYGRSDLMFSDSAVSLKPISPENQNYTMILDRSFARQVENLELIGGQLKS 707
F +F SP GR DL+F DSA+ I P + + L + ++NL +LK+
Sbjct: 305 FQLFGSPEGRRDLLFKDSALGFVRI-PSKVDSALYLGSRYLTALKNLRETAEELKA 359
Score = 109 bits (273), Expect = 9e-24
Identities = 70/233 (30%), Positives = 117/233 (50%), Gaps = 6/233 (2%)
Frame = +3
Query: 3 SGWVIPVNIAMETVQFRVYSDNLVYSFSELIARSCIPGILSDDYNPSKKNPLNLCEICAA 182
+GW IP+ + + + +F E ++SC PG +P +LC +CA
Sbjct: 484 AGWNIPMGL--------IANQTGSCAFDEFFSQSCAPGA-----DPKS----SLCALCAG 526
Query: 183 GGQ--DRCLPDSREQYYGDSGAFRCMLEN-GDVAFARHTTVHDNTDGRNPVDWARNRRSD 353
Q D+C+P+S+E+YYG +GAFRC+ E+ GDVAF ++ TV +NT+G + DWA+N +
Sbjct: 527 DDQGLDKCVPNSKEKYYGYTGAFRCLAEDVGDVAFVKNDTVWENTNGESSADWAKNLNRE 586
Query: 354 DYEILCPDGTRVDTYSWQKCNLGKIPGNVIVTGGFKSQPQRNEMWRLLRYAQEYFASDSN 533
D+ +LC DGT Q C L P + +V+ ++ + ++L + Q F +
Sbjct: 587 DFRLLCLDGTTKPVTEAQSCYLAVAPNHAVVSRSDRAA----HVEQVLLHQQALFGKNGK 642
Query: 534 NV---FTMFASPYGRSDLMFSDSAVSLKPISPENQNYTMILDRSFARQVENLE 683
N F +F S +L+F+D+ L + Y L + + NL+
Sbjct: 643 NCPDQFCLFKSE--TKNLLFNDNTECLAKLG-GRPTYEKYLGTEYVTAIANLK 692
>sp|P02788|TRFL_HUMAN Lactotransferrin precursor (Lactoferrin) [Contains: Kaliocin-1;
Lactoferroxin A; Lactoferroxin B; Lactoferroxin C]
Length = 711
Score = 126 bits (317), Expect = 7e-29
Identities = 68/227 (29%), Positives = 115/227 (50%), Gaps = 1/227 (0%)
Frame = +3
Query: 3 SGWVIPVNIAMETVQFRVYSDNLVYSFSELIARSCIPGILSDDYNPSKKNPLNLCEICAA 182
+GW +P+ + + + + + + + SC+PG + NLC +CA
Sbjct: 143 AGWNVPIGTLRPFLNWTGPPEPIEAAVARFFSASCVPGADKGQFP-------NLCRLCAG 195
Query: 183 GGQDRCLPDSREQYYGDSGAFRCMLEN-GDVAFARHTTVHDNTDGRNPVDWARNRRSDDY 359
G+++C S+E Y+ SGAF+C+ + GDVAF R +TV + D + D+Y
Sbjct: 196 TGENKCAFSSQEPYFSYSGAFKCLRDGAGDVAFIRESTVFE--------DLSDEAERDEY 247
Query: 360 EILCPDGTRVDTYSWQKCNLGKIPGNVIVTGGFKSQPQRNEMWRLLRYAQEYFASDSNNV 539
E+LCPD TR ++ C+L ++P + +V + + +W LLR AQE F D +
Sbjct: 248 ELLCPDNTRKPVDKFKDCHLARVPSHAVVARSVNGK--EDAIWNLLRQAQEKFGKDKSPK 305
Query: 540 FTMFASPYGRSDLMFSDSAVSLKPISPENQNYTMILDRSFARQVENL 680
F +F SP G+ DL+F DSA+ + P + + L + ++NL
Sbjct: 306 FQLFGSPSGQKDLLFKDSAIGFSRVPPRIDS-GLYLGSGYFTAIQNL 351
Score = 105 bits (261), Expect = 2e-22
Identities = 72/233 (30%), Positives = 117/233 (50%), Gaps = 6/233 (2%)
Frame = +3
Query: 3 SGWVIPVNIAMETVQFRVYSDNLVYSFSELIARSCIPGILSDDYNPSKKNPLNLCEICAA 182
+GW IP+ + +++ F E ++SC PG SD + NLC +C
Sbjct: 487 AGWNIPMGL--------LFNQTGSCKFDEYFSQSCAPG--SDPRS-------NLCALCIG 529
Query: 183 G--GQDRCLPDSREQYYGDSGAFRCMLEN-GDVAFARHTTVHDNTDGRNPVDWARNRRSD 353
G+++C+P+S E+YYG +GAFRC+ EN GDVAF + TV NTDG N WA++ +
Sbjct: 530 DEQGENKCVPNSNERYYGYTGAFRCLAENAGDVAFVKDVTVLQNTDGNNNEAWAKDLKLA 589
Query: 354 DYEILCPDGTRVDTYSWQKCNLGKIPGNVIVTGGFKSQPQRNEMWRLLRYAQEYF---AS 524
D+ +LC DG R + C+L P + +V+ K + + ++L + Q F S
Sbjct: 590 DFALLCLDGKRKPVTEARSCHLAMAPNHAVVSRMDKVE----RLKQVLLHQQAKFGRNGS 645
Query: 525 DSNNVFTMFASPYGRSDLMFSDSAVSLKPISPENQNYTMILDRSFARQVENLE 683
D + F +F S +L+F+D+ L + + Y L + + NL+
Sbjct: 646 DCPDKFCLFQSE--TKNLLFNDNTECLARLHGKT-TYEKYLGPQYVAGITNLK 695
>sp|Q921I1|TRFE_MOUSE Serotransferrin precursor (Transferrin) (Siderophilin) (Beta-1-metal
binding globulin)
Length = 697
Score = 126 bits (316), Expect = 9e-29
Identities = 74/228 (32%), Positives = 118/228 (51%), Gaps = 2/228 (0%)
Frame = +3
Query: 3 SGWVIPVNIAMETVQFRVYSDNLVYSFSELIARSCIPGILSDDYNPSKKNPLNLCEICAA 182
+GW IP+ + + F E ++ C PG +KN LC++C
Sbjct: 480 AGWNIPMGMLYNRINH--------CKFDEFFSQGCAPGY--------EKNS-TLCDLCI- 521
Query: 183 GGQDRCLPDSREQYYGDSGAFRCMLENGDVAFARHTTVHDNTDGRNPVDWARNRRSDDYE 362
G +C P+++E+Y G +GAFRC++E GDVAF +H TV DNT+G+NP +WA+N + +D+E
Sbjct: 522 -GPLKCAPNNKEEYNGYTGAFRCLVEKGDVAFVKHQTVLDNTEGKNPAEWAKNLKQEDFE 580
Query: 363 ILCPDGTRVDTYSWQKCNLGKIPGNVIVTGGFKSQPQRNEMWRLLRYAQE--YFASDSNN 536
+LCPDGTR + C+L + P +V+V S+ ++ + + +QE + SD
Sbjct: 581 LLCPDGTRKPVKDFASCHLAQAPNHVVV-----SRKEKAARVKAVLTSQETLFGGSDCTG 635
Query: 537 VFTMFASPYGRSDLMFSDSAVSLKPISPENQNYTMILDRSFARQVENL 680
F +F S DL+F D + PE L + + V N+
Sbjct: 636 NFCLFKST--TKDLLFRDDTKCFVKL-PEGTTPEKYLGAEYMQSVGNM 680
Score = 99.4 bits (246), Expect = 1e-20
Identities = 66/226 (29%), Positives = 110/226 (48%), Gaps = 1/226 (0%)
Frame = +3
Query: 3 SGWVIPVNIAMETVQFRVYSDNLVYSFSELIARSCIPGILSDDYNPSKKNPLNLCEICAA 182
+GWVIP+ + + L + S + SC+P +D K LC++C
Sbjct: 145 AGWVIPIGLLF--CKLSEPRSPLEKAVSSFFSGSCVP--CADPVAFPK-----LCQLCPG 195
Query: 183 GGQDRCLPDSREQYYGDSGAFRCMLENG-DVAFARHTTVHDNTDGRNPVDWARNRRSDDY 359
C S + ++G GAF+C+ + G DVAF +HTT+ + + D Y
Sbjct: 196 -----CGCSSTQPFFGYVGAFKCLKDGGGDVAFVKHTTIFEVLPEKAD--------RDQY 242
Query: 360 EILCPDGTRVDTYSWQKCNLGKIPGNVIVTGGFKSQPQRNEMWRLLRYAQEYFASDSNNV 539
E+LC D TR ++ C L +IP + +V K+ + + +W +L+ AQE+F +
Sbjct: 243 ELLCLDNTRKPVDQYEDCYLARIPSHAVVAR--KNNGKEDLIWEILKVAQEHFGKGKSKD 300
Query: 540 FTMFASPYGRSDLMFSDSAVSLKPISPENQNYTMILDRSFARQVEN 677
F +F+SP G+ DL+F DSA L + P +Y + L ++ + N
Sbjct: 301 FQLFSSPLGK-DLLFKDSAFGLLRV-PPRMDYRLYLGHNYVTAIRN 344
>sp|P02789|TRFE_CHICK Ovotransferrin precursor (Conalbumin) (Allergen Gal d 3) (Gal d III)
(Serum transferrin)
Length = 705
Score = 125 bits (313), Expect = 2e-28
Identities = 74/234 (31%), Positives = 120/234 (51%), Gaps = 7/234 (2%)
Frame = +3
Query: 3 SGWVIPVNIAMETVQFRVYSDNLVYSFSELIARSCIPGILSDDYNPSKKNPLN--LCEIC 176
+GWVIP+ + +++ +F E + C PG +P N LC++C
Sbjct: 481 AGWVIPMGL--------IHNRTGTCNFDEYFSEGCAPG-----------SPPNSRLCQLC 521
Query: 177 AAGG---QDRCLPDSREQYYGDSGAFRCMLENGDVAFARHTTVHDNTDGRNPVDWARNRR 347
G ++C+ S E+Y+G +GA RC++E GDVAF +H+TV +NT G+N DWA+N +
Sbjct: 522 QGSGGIPPEKCVASSHEKYFGYTGALRCLVEKGDVAFIQHSTVEENTGGKNKADWAKNLQ 581
Query: 348 SDDYEILCPDGTRVDTYSWQKCNLGKIPGNVIVTGGFKSQPQRNEMWRLLRYAQEYFA-- 521
DD+E+LC DG R + +++CNL ++P + +V K+ N++ LL ++ F
Sbjct: 582 MDDFELLCTDGRRANVMDYRECNLAEVPTHAVVVRPEKA----NKIRDLLERQEKRFGVN 637
Query: 522 SDSNNVFTMFASPYGRSDLMFSDSAVSLKPISPENQNYTMILDRSFARQVENLE 683
+ F MF S DL+F D L + E Y L F + +L+
Sbjct: 638 GSEKSKFMMFESQ--NKDLLFKDLTKCLFKVR-EGTTYKEFLGDKFYTVISSLK 688
Score = 91.7 bits (226), Expect = 2e-18
Identities = 58/212 (27%), Positives = 101/212 (47%), Gaps = 8/212 (3%)
Frame = +3
Query: 3 SGWVIPVNIAMETVQFR---VYSDNLVYSFSELIARSCIPGILSDDYNPSKKNPLNLCEI 173
+GW IP+ + + S ++ + ++ + SC+PG + LC
Sbjct: 142 AGWNIPIGTLLHRGAIEWEGIESGSVEQAVAKFFSASCVPGATIEQ---------KLCRQ 192
Query: 174 CAAGGQDRCLPDSREQYYGDSGAFRCMLEN-GDVAFARHTTVHDNTDGRNPVDWARNRRS 350
C + +C ++ Y G SGAF C+ + GDVAF +HTTV++N +
Sbjct: 193 CKGDPKTKCARNA--PYSGYSGAFHCLKDGKGDVAFVKHTTVNENAPDQK---------- 240
Query: 351 DDYEILCPDGTRVDTYSWQKCNLGKIPGNVIVTGGFKSQPQRNEMWRLLRYAQEYFASDS 530
D+YE+LC DG+R +++ CN ++ + +V + + ++W L AQ F D+
Sbjct: 241 DEYELLCLDGSRQPVDNYKTCNWARVAAHAVVA---RDDNKVEDIWSFLSKAQSDFGVDT 297
Query: 531 NNVFTMFASPYGR----SDLMFSDSAVSLKPI 614
+ F +F P + DL+F DSA+ LK +
Sbjct: 298 KSDFHLFGPPGKKDPVLKDLLFKDSAIMLKRV 329
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 103,343,664
Number of Sequences: 369166
Number of extensions: 2233230
Number of successful extensions: 5857
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 5396
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5699
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 8582957970
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)