Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_015_K09
(473 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q66HG5|TM9S2_RAT Transmembrane 9 superfamily protein mem... 221 7e-58
sp|Q99805|TM9S2_HUMAN Transmembrane 9 superfamily protein m... 221 7e-58
sp|P58021|TM9S2_MOUSE Transmembrane 9 superfamily protein m... 221 7e-58
sp|Q5R8Y6|TM9S2_PONPY Transmembrane 9 superfamily protein m... 221 7e-58
sp|Q92544|TM9S4_HUMAN Transmembrane 9 superfamily protein m... 167 9e-42
sp|P32802|EMP70_YEAST Endosomal P24A protein precursor (70 ... 120 2e-27
sp|Q9DBU0|TM9S1_MOUSE Transmembrane 9 superfamily protein m... 110 2e-24
sp|O15321|TM9S1_HUMAN Transmembrane 9 superfamily protein m... 110 2e-24
sp|Q5R8F1|TM9S1_PONPY Transmembrane 9 superfamily protein m... 110 2e-24
sp|Q9ET30|TM9S3_MOUSE Transmembrane 9 superfamily protein m... 98 8e-21
>sp|Q66HG5|TM9S2_RAT Transmembrane 9 superfamily protein member 2 precursor
Length = 663
Score = 221 bits (563), Expect = 7e-58
Identities = 101/156 (64%), Positives = 119/156 (76%)
Frame = +2
Query: 5 SARLYKMMSGEKWKSNVLLTAFLCPVSVFGIFFVLNIVLWASGSSAAVPFTTILGLLAMW 184
+AR YK GEKWK+NVLLT+FLCP VF FF++N++LW GSSAA+PF T++ +LA+W
Sbjct: 418 AARFYKSFGGEKWKTNVLLTSFLCPGIVFADFFIMNLILWGEGSSAAIPFGTLVAILALW 477
Query: 185 FLISVPLCFVGAYFGFKKQPISQPVRTNQIPRQIPYQYLYTRSIPSILMGGVLPFGCIFI 364
F ISVPL F+GAYFGFKK I PVRTNQIPRQIP Q YT+ +P I+MGG+LPFGCIFI
Sbjct: 478 FCISVPLTFIGAYFGFKKNAIEHPVRTNQIPRQIPEQSFYTKPLPGIIMGGILPFGCIFI 537
Query: 365 QLFFILNSIWSTYVYYMFGXXXXXXXXXXXTCSETT 472
QLFFILNSIWS +YYMFG TCSE T
Sbjct: 538 QLFFILNSIWSHQMYYMFGFLFLVFIILVITCSEAT 573
>sp|Q99805|TM9S2_HUMAN Transmembrane 9 superfamily protein member 2 precursor (p76)
Length = 663
Score = 221 bits (563), Expect = 7e-58
Identities = 101/156 (64%), Positives = 119/156 (76%)
Frame = +2
Query: 5 SARLYKMMSGEKWKSNVLLTAFLCPVSVFGIFFVLNIVLWASGSSAAVPFTTILGLLAMW 184
+AR YK GEKWK+NVLLT+FLCP VF FF++N++LW GSSAA+PF T++ +LA+W
Sbjct: 418 AARFYKSFGGEKWKTNVLLTSFLCPGIVFADFFIMNLILWGEGSSAAIPFGTLVAILALW 477
Query: 185 FLISVPLCFVGAYFGFKKQPISQPVRTNQIPRQIPYQYLYTRSIPSILMGGVLPFGCIFI 364
F ISVPL F+GAYFGFKK I PVRTNQIPRQIP Q YT+ +P I+MGG+LPFGCIFI
Sbjct: 478 FCISVPLTFIGAYFGFKKNAIEHPVRTNQIPRQIPEQSFYTKPLPGIIMGGILPFGCIFI 537
Query: 365 QLFFILNSIWSTYVYYMFGXXXXXXXXXXXTCSETT 472
QLFFILNSIWS +YYMFG TCSE T
Sbjct: 538 QLFFILNSIWSHQMYYMFGFLFLVFIILVITCSEAT 573
>sp|P58021|TM9S2_MOUSE Transmembrane 9 superfamily protein member 2 precursor
Length = 662
Score = 221 bits (563), Expect = 7e-58
Identities = 101/156 (64%), Positives = 119/156 (76%)
Frame = +2
Query: 5 SARLYKMMSGEKWKSNVLLTAFLCPVSVFGIFFVLNIVLWASGSSAAVPFTTILGLLAMW 184
+AR YK GEKWK+NVLLT+FLCP VF FF++N++LW GSSAA+PF T++ +LA+W
Sbjct: 417 AARFYKSFGGEKWKTNVLLTSFLCPGIVFADFFIMNLILWGEGSSAAIPFGTLVAILALW 476
Query: 185 FLISVPLCFVGAYFGFKKQPISQPVRTNQIPRQIPYQYLYTRSIPSILMGGVLPFGCIFI 364
F ISVPL F+GAYFGFKK I PVRTNQIPRQIP Q YT+ +P I+MGG+LPFGCIFI
Sbjct: 477 FCISVPLTFIGAYFGFKKNAIEHPVRTNQIPRQIPEQSFYTKPLPGIIMGGILPFGCIFI 536
Query: 365 QLFFILNSIWSTYVYYMFGXXXXXXXXXXXTCSETT 472
QLFFILNSIWS +YYMFG TCSE T
Sbjct: 537 QLFFILNSIWSHQMYYMFGFLFLVFIILVITCSEAT 572
>sp|Q5R8Y6|TM9S2_PONPY Transmembrane 9 superfamily protein member 2 precursor
Length = 663
Score = 221 bits (563), Expect = 7e-58
Identities = 101/156 (64%), Positives = 119/156 (76%)
Frame = +2
Query: 5 SARLYKMMSGEKWKSNVLLTAFLCPVSVFGIFFVLNIVLWASGSSAAVPFTTILGLLAMW 184
+AR YK GEKWK+NVLLT+FLCP VF FF++N++LW GSSAA+PF T++ +LA+W
Sbjct: 418 AARFYKSFGGEKWKTNVLLTSFLCPGIVFADFFIMNLILWGEGSSAAIPFGTLVAILALW 477
Query: 185 FLISVPLCFVGAYFGFKKQPISQPVRTNQIPRQIPYQYLYTRSIPSILMGGVLPFGCIFI 364
F ISVPL F+GAYFGFKK I PVRTNQIPRQIP Q YT+ +P I+MGG+LPFGCIFI
Sbjct: 478 FCISVPLTFIGAYFGFKKNAIEHPVRTNQIPRQIPEQSFYTKPLPGIIMGGILPFGCIFI 537
Query: 365 QLFFILNSIWSTYVYYMFGXXXXXXXXXXXTCSETT 472
QLFFILNSIWS +YYMFG TCSE T
Sbjct: 538 QLFFILNSIWSHQMYYMFGFLFLVFIILVITCSEAT 573
>sp|Q92544|TM9S4_HUMAN Transmembrane 9 superfamily protein member 4
Length = 625
Score = 167 bits (424), Expect = 9e-42
Identities = 79/154 (51%), Positives = 98/154 (63%)
Frame = +2
Query: 5 SARLYKMMSGEKWKSNVLLTAFLCPVSVFGIFFVLNIVLWASGSSAAVPFTTILGLLAMW 184
+ RLY+ + G +WK TA L P VFGI FVLN +W SS AVPF T++ LL MW
Sbjct: 380 AGRLYRTLKGHRWKKGAFCTATLYPGVVFGICFVLNCFIWGKHSSGAVPFPTMVALLCMW 439
Query: 185 FLISVPLCFVGAYFGFKKQPISQPVRTNQIPRQIPYQYLYTRSIPSILMGGVLPFGCIFI 364
F IS+PL ++G YFGF+KQP PVRTNQIPRQIP Q Y ILM G+LPFG +FI
Sbjct: 440 FGISLPLVYLGYYFGFRKQPYDNPVRTNQIPRQIPEQRWYMNRFVGILMAGILPFGAMFI 499
Query: 365 QLFFILNSIWSTYVYYMFGXXXXXXXXXXXTCSE 466
+LFFI ++IW YY+FG +CS+
Sbjct: 500 ELFFIFSAIWENQFYYLFGFLFLVFIILVVSCSQ 533
>sp|P32802|EMP70_YEAST Endosomal P24A protein precursor (70 kDa endomembrane protein)
(Pheromone alpha-factor transporter) (Acidic 24 kDa late
endocytic intermediate component)
Length = 667
Score = 120 bits (300), Expect = 2e-27
Identities = 56/140 (40%), Positives = 86/140 (61%), Gaps = 1/140 (0%)
Frame = +2
Query: 5 SARLYKMMSGEKWKSNVLLTAFLCPVSVFGIFFVLNIVLWASGSSAAVPFTTILGLLAMW 184
S +YK +G WK+N++LT L P ++ I LN L SS +P +T+ ++ +W
Sbjct: 422 SMGIYKFFNGPYWKANLILTPLLVPGAILLIIIALNFFLMFVHSSGVIPASTLFFMVFLW 481
Query: 185 FLISVPLCFVGAYFGFKKQPISQ-PVRTNQIPRQIPYQYLYTRSIPSILMGGVLPFGCIF 361
FL S+PL F G+ K+ + P +TNQI RQIP+Q Y ++IP+ L+ G+ PFG I
Sbjct: 482 FLFSIPLSFAGSLIARKRCHWDEHPTKTNQIARQIPFQPWYLKTIPATLIAGIFPFGSIA 541
Query: 362 IQLFFILNSIWSTYVYYMFG 421
++L+FI S+W ++YMFG
Sbjct: 542 VELYFIYTSLWFNKIFYMFG 561
>sp|Q9DBU0|TM9S1_MOUSE Transmembrane 9 superfamily protein member 1 precursor
Length = 606
Score = 110 bits (275), Expect = 2e-24
Identities = 54/140 (38%), Positives = 82/140 (58%), Gaps = 1/140 (0%)
Frame = +2
Query: 5 SARLYKMMSGEKWKSNVLLTAFLCPVSVFGIFFVLNIVLWASGSSAAVPFTTILGLLAMW 184
S+ Y+ + GE+W N++LT+ L V F + V+N V WA+GS+ A+P TTIL LL +W
Sbjct: 360 SSHFYRQIGGERWVWNIILTSSLFSVPFFLTWSVVNSVHWANGSTQALPATTILLLLTVW 419
Query: 185 FLISVPLCFVGAYFGFKK-QPISQPVRTNQIPRQIPYQYLYTRSIPSILMGGVLPFGCIF 361
L+ PL +G FG P P RT I R+IP Q Y ++ + +GG LPF I
Sbjct: 420 LLVGFPLTVIGGIFGKNNASPFDAPCRTKNIAREIPPQPWYKSTVIHMTVGGFLPFSAIS 479
Query: 362 IQLFFILNSIWSTYVYYMFG 421
++L++I ++W Y ++G
Sbjct: 480 VELYYIFATVWGREQYTLYG 499
>sp|O15321|TM9S1_HUMAN Transmembrane 9 superfamily protein member 1 precursor (hMP70)
Length = 606
Score = 110 bits (274), Expect = 2e-24
Identities = 54/140 (38%), Positives = 81/140 (57%), Gaps = 1/140 (0%)
Frame = +2
Query: 5 SARLYKMMSGEKWKSNVLLTAFLCPVSVFGIFFVLNIVLWASGSSAAVPFTTILGLLAMW 184
S+ Y+ + GE+W N++LT L V F + V+N V WA+GS+ A+P TTIL LL +W
Sbjct: 360 SSHFYRQIGGERWVWNIILTTSLFSVPFFLTWSVVNSVHWANGSTQALPATTILLLLTVW 419
Query: 185 FLISVPLCFVGAYFGFKK-QPISQPVRTNQIPRQIPYQYLYTRSIPSILMGGVLPFGCIF 361
L+ PL +G FG P P RT I R+IP Q Y ++ + +GG LPF I
Sbjct: 420 LLVGFPLTVIGGIFGKNNASPFDAPCRTKNIAREIPPQPWYKSTVIHMTVGGFLPFSAIS 479
Query: 362 IQLFFILNSIWSTYVYYMFG 421
++L++I ++W Y ++G
Sbjct: 480 VELYYIFATVWGREQYTLYG 499
>sp|Q5R8F1|TM9S1_PONPY Transmembrane 9 superfamily protein member 1 precursor
Length = 606
Score = 110 bits (274), Expect = 2e-24
Identities = 54/140 (38%), Positives = 81/140 (57%), Gaps = 1/140 (0%)
Frame = +2
Query: 5 SARLYKMMSGEKWKSNVLLTAFLCPVSVFGIFFVLNIVLWASGSSAAVPFTTILGLLAMW 184
S+ Y+ + GE+W N++LT L V F + V+N V WA+GS+ A+P TTIL LL +W
Sbjct: 360 SSHFYRQIGGERWVWNIILTTSLFSVPFFLTWSVVNSVHWANGSTQALPATTILLLLTVW 419
Query: 185 FLISVPLCFVGAYFGFKK-QPISQPVRTNQIPRQIPYQYLYTRSIPSILMGGVLPFGCIF 361
L+ PL +G FG P P RT I R+IP Q Y ++ + +GG LPF I
Sbjct: 420 LLVGFPLTVIGGIFGKNNASPFDAPCRTKNIAREIPPQPWYKSTVIHMTVGGFLPFSAIS 479
Query: 362 IQLFFILNSIWSTYVYYMFG 421
++L++I ++W Y ++G
Sbjct: 480 VELYYIFATVWGREQYTLYG 499
>sp|Q9ET30|TM9S3_MOUSE Transmembrane 9 superfamily protein member 3 precursor
Length = 587
Score = 98.2 bits (243), Expect = 8e-21
Identities = 48/142 (33%), Positives = 76/142 (53%), Gaps = 2/142 (1%)
Frame = +2
Query: 2 YSARLYKMMSGEKWKSNVLLTAFLCPVSVFGIFFVLNIVLWASGSSAAVPFTTILGLLAM 181
+ LY G +W + + AFL P V G F +N + +S A+PF T++ + +
Sbjct: 340 FGGSLYARQGGRRWIKQMFIGAFLIPAMVCGTAFFINFIAIYYHASRAIPFGTMVAVCCI 399
Query: 182 WFLISVPLCFVGAYFG--FKKQPISQPVRTNQIPRQIPYQYLYTRSIPSILMGGVLPFGC 355
F + +PL VG G QP + P R N +PR IP + + + +GG+LPFG
Sbjct: 400 CFFVILPLNLVGTILGRNLSGQP-NFPCRVNAVPRPIPEKKWFMEPAVIVCLGGILPFGS 458
Query: 356 IFIQLFFILNSIWSTYVYYMFG 421
IFI+++FI S W+ +YY++G
Sbjct: 459 IFIEMYFIFTSFWAYKIYYVYG 480
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 59,790,693
Number of Sequences: 369166
Number of extensions: 1244269
Number of successful extensions: 3549
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3438
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3542
length of database: 68,354,980
effective HSP length: 101
effective length of database: 49,696,745
effective search space used: 2783017720
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)