Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_015_I12
(767 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9Y5H4|PCDG1_HUMAN Protocadherin gamma A1 precursor (PCD... 55 3e-07
sp|Q5DRC2|PCDG1_PANTR Protocadherin gamma A1 precursor (PCD... 54 4e-07
sp|Q08174|PCDH1_HUMAN Protocadherin 1 precursor (Protocadhe... 51 4e-06
sp|Q5DRB5|PCDG5_PANTR Protocadherin gamma A5 precursor (PCD... 50 9e-06
sp|Q9Y5G8|PCDG5_HUMAN Protocadherin gamma A5 precursor (PCD... 50 9e-06
sp|Q5DRC3|PCDBG_PANTR Protocadherin beta 16 precursor (PCDH... 50 9e-06
sp|O60330|PCDGC_HUMAN Protocadherin gamma A12 precursor (PC... 49 1e-05
sp|Q5DRB9|PCDGC_PANTR Protocadherin gamma A12 precursor (PC... 49 2e-05
sp|Q24292|DS_DROME Dachsous protein precursor (Adherin) 48 3e-05
sp|Q9HCU4|CELR2_HUMAN Cadherin EGF LAG seven-pass G-type re... 48 3e-05
>sp|Q9Y5H4|PCDG1_HUMAN Protocadherin gamma A1 precursor (PCDH-gamma-A1)
Length = 931
Score = 54.7 bits (130), Expect = 3e-07
Identities = 38/129 (29%), Positives = 57/129 (44%), Gaps = 5/129 (3%)
Frame = +1
Query: 28 EACSTQTLEIHVQVTDL-----VFLQKHYQMEILENFTVDCEILQVQAVYKNSKKSNKIA 192
E + TL I++QV D F Q Y + + EN + ++L V A + + ++
Sbjct: 219 EPVRSGTLRIYIQVVDANDNPPAFTQAQYHINVPENVPLGTQLLMVNATDPDEGANGEVT 278
Query: 193 YGFHLGDNIIRDTFRISRNTGSIKLKRKLLAKFRQKYKFRVYAVYLMDPMLPKAVANVSI 372
Y FH D+ + FR+ TG I K L ++YK V D A V I
Sbjct: 279 YSFHNVDHRVAQIFRLDSYTGEISNKEPL---DFEEYKMYSMEVQAQDGAGLMAKVKVLI 335
Query: 373 TVKDINDNS 399
V D+NDN+
Sbjct: 336 KVLDVNDNA 344
>sp|Q5DRC2|PCDG1_PANTR Protocadherin gamma A1 precursor (PCDH-gamma-A1)
Length = 931
Score = 54.3 bits (129), Expect = 4e-07
Identities = 38/129 (29%), Positives = 57/129 (44%), Gaps = 5/129 (3%)
Frame = +1
Query: 28 EACSTQTLEIHVQVTDL-----VFLQKHYQMEILENFTVDCEILQVQAVYKNSKKSNKIA 192
E + TL I++QV D F Q Y + + EN + ++L V A + + ++
Sbjct: 219 EPVRSGTLRIYIQVVDANDNPPAFTQAQYHINVPENVPLGTQLLMVNATDPDEGANGEVT 278
Query: 193 YGFHLGDNIIRDTFRISRNTGSIKLKRKLLAKFRQKYKFRVYAVYLMDPMLPKAVANVSI 372
Y FH D+ + F + TG I K L ++YK V D A A V I
Sbjct: 279 YSFHNVDHRVAQIFHLDSYTGEISNKEPLDF---EEYKMYSMEVQAQDGAGLMAKAKVLI 335
Query: 373 TVKDINDNS 399
V D+NDN+
Sbjct: 336 KVLDVNDNT 344
>sp|Q08174|PCDH1_HUMAN Protocadherin 1 precursor (Protocadherin 42) (PC42) (Cadherin-like
protein 1)
Length = 1026
Score = 50.8 bits (120), Expect = 4e-06
Identities = 33/109 (30%), Positives = 54/109 (49%)
Frame = +1
Query: 82 FLQKHYQMEILENFTVDCEILQVQAVYKNSKKSNKIAYGFHLGDNIIRDTFRISRNTGSI 261
F + Y+ E+ EN + ++QV+A + + +I Y FH ++R R+ RNTG I
Sbjct: 246 FERPSYEAELSENSPIGHSVIQVKANDSDQGANAEIEYTFHQAPEVVRRLLRLDRNTGLI 305
Query: 262 KLKRKLLAKFRQKYKFRVYAVYLMDPMLPKAVANVSITVKDINDNSSVI 408
++ + + +F V A A A V +TVKD+NDN+ I
Sbjct: 306 TVQGPVDREDLSTLRFSVLAKD-RGTNPKSARAQVVVTVKDMNDNAPTI 353
>sp|Q5DRB5|PCDG5_PANTR Protocadherin gamma A5 precursor (PCDH-gamma-A5)
Length = 931
Score = 49.7 bits (117), Expect = 9e-06
Identities = 33/125 (26%), Positives = 58/125 (46%), Gaps = 7/125 (5%)
Frame = +1
Query: 58 HVQVTDL-------VFLQKHYQMEILENFTVDCEILQVQAVYKNSKKSNKIAYGFHLGDN 216
H++VT L +F Y + + EN V +L + A + + K+ Y F +
Sbjct: 227 HIRVTVLDANDNAPLFTPSEYSVSVPENIPVGTRLLMLTATDPDEGINGKLTYSFRNEEE 286
Query: 217 IIRDTFRISRNTGSIKLKRKLLAKFRQKYKFRVYAVYLMDPMLPKAVANVSITVKDINDN 396
I +TF++ N G I + L ++ +F + V D A A V +TV+D+NDN
Sbjct: 287 KISETFQLDSNLGEISTLQSL---DYEESRFYLMEVVAQDGGALVASAKVVVTVQDVNDN 343
Query: 397 SSVIV 411
+ ++
Sbjct: 344 APEVI 348
>sp|Q9Y5G8|PCDG5_HUMAN Protocadherin gamma A5 precursor (PCDH-gamma-A5)
Length = 931
Score = 49.7 bits (117), Expect = 9e-06
Identities = 33/125 (26%), Positives = 58/125 (46%), Gaps = 7/125 (5%)
Frame = +1
Query: 58 HVQVTDL-------VFLQKHYQMEILENFTVDCEILQVQAVYKNSKKSNKIAYGFHLGDN 216
H++VT L +F Y + + EN V +L + A + + K+ Y F +
Sbjct: 227 HIRVTVLDANDNAPLFTPSEYSVSVPENIPVGTRLLMLTATDPDEGINGKLTYSFRNEEE 286
Query: 217 IIRDTFRISRNTGSIKLKRKLLAKFRQKYKFRVYAVYLMDPMLPKAVANVSITVKDINDN 396
I +TF++ N G I + L ++ +F + V D A A V +TV+D+NDN
Sbjct: 287 KISETFQLDSNLGEISTLQSL---DYEESRFYLMEVVAQDGGALVASAKVVVTVQDVNDN 343
Query: 397 SSVIV 411
+ ++
Sbjct: 344 APEVI 348
>sp|Q5DRC3|PCDBG_PANTR Protocadherin beta 16 precursor (PCDH-beta16)
Length = 795
Score = 49.7 bits (117), Expect = 9e-06
Identities = 37/123 (30%), Positives = 60/123 (48%), Gaps = 2/123 (1%)
Frame = +1
Query: 37 STQTLEIHVQVTDLV--FLQKHYQMEILENFTVDCEILQVQAVYKNSKKSNKIAYGFHLG 210
++Q L + V + D V F Q+ Y++++ EN + ++ V A ++ +++Y F
Sbjct: 225 TSQVLIVIVDINDNVPEFAQRRYEVQVPENTPIGSLVITVSARDLDAGTHGELSYSFFQY 284
Query: 211 DNIIRDTFRISRNTGSIKLKRKLLAKFRQKYKFRVYAVYLMDPMLPKAVANVSITVKDIN 390
N I F I+ TG I+LK+ L + Q Y V A D V+I V DIN
Sbjct: 285 SNQIIQAFEINSITGEIRLKKALDFEEIQSYHMEVEA---SDGGGLSGKCTVAIEVMDIN 341
Query: 391 DNS 399
DN+
Sbjct: 342 DNA 344
>sp|O60330|PCDGC_HUMAN Protocadherin gamma A12 precursor (PCDH-gamma-A12) (Cadherin-21)
(Fibroblast cadherin 3)
Length = 932
Score = 48.9 bits (115), Expect = 1e-05
Identities = 38/129 (29%), Positives = 58/129 (44%), Gaps = 5/129 (3%)
Frame = +1
Query: 40 TQTLEIHVQVTDL-----VFLQKHYQMEILENFTVDCEILQVQAVYKNSKKSNKIAYGFH 204
T T I V V D F Q Y+ + EN + ++L V A + + ++ Y F
Sbjct: 223 TGTARIRVMVLDANDNAPAFAQPEYRASVPENLALGTQLLVVNATDPDEGVNAEVRYSFR 282
Query: 205 LGDNIIRDTFRISRNTGSIKLKRKLLAKFRQKYKFRVYAVYLMDPMLPKAVANVSITVKD 384
D+ F++ N+G+I +L + Y+ V A MD A A V ITV D
Sbjct: 283 YVDDKAAQVFKLDCNSGTISTIGELDHEESGFYQMEVQA---MDNAGYSARAKVLITVLD 339
Query: 385 INDNSSVIV 411
+NDN+ +V
Sbjct: 340 VNDNAPEVV 348
>sp|Q5DRB9|PCDGC_PANTR Protocadherin gamma A12 precursor (PCDH-gamma-A12)
Length = 932
Score = 48.5 bits (114), Expect = 2e-05
Identities = 38/129 (29%), Positives = 58/129 (44%), Gaps = 5/129 (3%)
Frame = +1
Query: 40 TQTLEIHVQVTDL-----VFLQKHYQMEILENFTVDCEILQVQAVYKNSKKSNKIAYGFH 204
T T I V V D F Q Y+ + EN + ++L V A + + ++ Y F
Sbjct: 223 TGTARIRVMVLDANDNAPAFAQPEYRASVPENLALGTQLLVVNATDPDEGVNAEVRYSFR 282
Query: 205 LGDNIIRDTFRISRNTGSIKLKRKLLAKFRQKYKFRVYAVYLMDPMLPKAVANVSITVKD 384
D+ F++ N+G+I +L + Y+ V A MD A A V ITV D
Sbjct: 283 SVDDKAAQVFKLDCNSGTISTIGELDHEESGFYQMEVQA---MDNAGYSARAKVLITVLD 339
Query: 385 INDNSSVIV 411
+NDN+ +V
Sbjct: 340 VNDNAPEVV 348
>sp|Q24292|DS_DROME Dachsous protein precursor (Adherin)
Length = 3503
Score = 47.8 bits (112), Expect = 3e-05
Identities = 34/114 (29%), Positives = 55/114 (48%)
Frame = +1
Query: 79 VFLQKHYQMEILENFTVDCEILQVQAVYKNSKKSNKIAYGFHLGDNIIRDTFRISRNTGS 258
+F Q Y + EN TV +LQV A ++ ++ + Y + + FRI TG+
Sbjct: 232 IFNQSRYFATVPENATVGTSVLQVYASDTDADENGLVEYAINRRQSDKEQMFRIDPRTGA 291
Query: 259 IKLKRKLLAKFRQKYKFRVYAVYLMDPMLPKAVANVSITVKDINDNSSVIVTIF 420
I + + L + ++ ++ V A + L + A VSI V D+NDN I IF
Sbjct: 292 IYINKALDFETKELHELVVVAKDHGEQPL-ETTAFVSIRVTDVNDNQPTINVIF 344
Score = 32.3 bits (72), Expect = 1.5
Identities = 33/131 (25%), Positives = 49/131 (37%), Gaps = 25/131 (19%)
Frame = +1
Query: 82 FLQKHYQMEILENFTVDCEILQVQAVYKNSKKSNKIAYGFHLGDNIIRDTFRISRNTGSI 261
FLQ Y+ ILEN +LQV A + ++ ++Y G + D F + G I
Sbjct: 1666 FLQAVYRATILENVPSGSFVLQVTAKSLHGAENANLSYEIPAG--VANDLFHVDWQRGII 1723
Query: 262 KLKRKLLAKFRQKYKFRVYAVYLMDPMLPKA-------------------------VANV 366
+ + + + Y V VY+ D VA +
Sbjct: 1724 TTRGQFDRESQASY---VLPVYVRDANRQSTLSSSAVRKQRSSDSIGDTSNGQHFDVATI 1780
Query: 367 SITVKDINDNS 399
ITV D+NDNS
Sbjct: 1781 YITVGDVNDNS 1791
Score = 30.4 bits (67), Expect = 5.5
Identities = 32/129 (24%), Positives = 53/129 (41%), Gaps = 5/129 (3%)
Frame = +1
Query: 40 TQTLEIHVQVTDLVFLQKHYQMEILENFTVDCEILQVQAVYKNSKKSNKIAYGFHLGDNI 219
T T I VQ+ D+ Q + L + E+ V + A + LG
Sbjct: 2356 TGTATIRVQIVDVNDNQPTFPPNNLVTVSEATELGAVITSISANDVDTYPALTYRLGAES 2415
Query: 220 IRDT-----FRISRNTGSIKLKRKLLAKFRQKYKFRVYAVYLMDPMLPKAVANVSITVKD 384
D F + R +G + LKR+L + +Q+Y+ V A +A +++ V D
Sbjct: 2416 TVDIENMSIFALDRYSGKLVLKRRLDYELQQEYELDVIA----SDAAHEARTVLTVRVND 2471
Query: 385 INDNSSVIV 411
NDN+ V +
Sbjct: 2472 ENDNAPVFL 2480
Score = 30.0 bits (66), Expect = 7.2
Identities = 30/129 (23%), Positives = 52/129 (40%), Gaps = 5/129 (3%)
Frame = +1
Query: 55 IHVQVTDL-----VFLQKHYQMEILENFTVDCEILQVQAVYKNSKKSNKIAYGFHLGDNI 219
I +++TD+ F Q Y ++E +LQV A ++ ++ + Y
Sbjct: 437 IFLRITDVNDNPPEFEQDLYHANVMEVADPGTSVLQVLAHDRDEGLNSALTYSLAETPET 496
Query: 220 IRDTFRISRNTGSIKLKRKLLAKFRQKYKFRVYAVYLMDPMLPKAVANVSITVKDINDNS 399
F+I TG I + + + + V A P L + A V +T+ D+NDN
Sbjct: 497 HAQWFQIDPQTGLITTRSHIDCETEPVPQLTVVARDGGVPPL-SSTATVLVTIHDVNDNE 555
Query: 400 SVIVTIFGN 426
+ F N
Sbjct: 556 PIFDQSFYN 564
>sp|Q9HCU4|CELR2_HUMAN Cadherin EGF LAG seven-pass G-type receptor 2 precursor (Epidermal
growth factor-like 2) (Multiple epidermal growth
factor-like domains 3) (Flamingo 1)
Length = 2923
Score = 47.8 bits (112), Expect = 3e-05
Identities = 34/110 (30%), Positives = 56/110 (50%), Gaps = 2/110 (1%)
Frame = +1
Query: 82 FLQKHYQMEILENFTVDCEILQVQAVYKNSKKSNKIAYGFHLGDNIIRDTFRISRNTGSI 261
FL+ YQ + E+ +LQ+ A ++S + ++ Y F GD+ D F + +G +
Sbjct: 815 FLRDSYQGSVYEDVPPFTSVLQISATDRDSGLNGRVFYTFQGGDDGDGD-FIVESTSGIV 873
Query: 262 KLKRKLLAKFRQKYKFRVYAVYLMDPMLPKA--VANVSITVKDINDNSSV 405
+ R+L + +Y R YAV D +P A V++TV D+NDN V
Sbjct: 874 RTLRRLDRENVAQYVLRAYAV---DKGMPPARTPMEVTVTVLDVNDNPPV 920
Score = 42.4 bits (98), Expect = 0.001
Identities = 29/111 (26%), Positives = 53/111 (47%)
Frame = +1
Query: 82 FLQKHYQMEILENFTVDCEILQVQAVYKNSKKSNKIAYGFHLGDNIIRDTFRISRNTGSI 261
F +K Y +++ E+ T +L+V A ++ + + Y G+ R F + TG++
Sbjct: 399 FSEKRYVVQVREDVTPGAPVLRVTASDRDKGSNAVVHYSIMSGN--ARGQFYLDAQTGAL 456
Query: 262 KLKRKLLAKFRQKYKFRVYAVYLMDPMLPKAVANVSITVKDINDNSSVIVT 414
+ L + ++Y RV A P L V++ V DINDN+ + V+
Sbjct: 457 DVVSPLDYETTKEYTLRVRAQDGGRPPLSNVSGLVTVQVLDINDNAPIFVS 507
Score = 40.8 bits (94), Expect = 0.004
Identities = 36/121 (29%), Positives = 61/121 (50%), Gaps = 6/121 (4%)
Frame = +1
Query: 55 IHVQVTDL-----VFLQKHYQMEILENFTVDCEILQVQAVYKNSKKSNKIAYGFH-LGDN 216
+ VQV D+ +F+ +Q +LE+ + +L VQA+ ++ + ++ Y +G +
Sbjct: 491 VTVQVLDINDNAPIFVSTPFQATVLESVPLGYLVLHVQAIDADAGDNARLEYRLAGVGHD 550
Query: 217 IIRDTFRISRNTGSIKLKRKLLAKFRQKYKFRVYAVYLMDPMLPKAVANVSITVKDINDN 396
F I+ TG I + +L + Y F V A P L A A+VS+TV D+NDN
Sbjct: 551 F---PFTINNGTGWISVAAELDREEVDFYSFGVEARDHGTPALT-ASASVSVTVLDVNDN 606
Query: 397 S 399
+
Sbjct: 607 N 607
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 73,562,995
Number of Sequences: 369166
Number of extensions: 1257182
Number of successful extensions: 3396
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3052
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3365
length of database: 68,354,980
effective HSP length: 108
effective length of database: 48,403,600
effective search space used: 7115329200
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)