Planarian EST Database


Dr_sW_015_I10

BLASTX 2.2.12 [Aug-07-2005]

Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= Dr_sW_015_I10
         (786 letters)

Database: Non-redundant SwissProt sequences 
           184,735 sequences; 68,354,980 total letters



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

sp|P21195|PDIA1_RABIT  Protein disulfide-isomerase precursor...    81   4e-15
sp|P07237|PDIA1_HUMAN  Protein disulfide-isomerase precursor...    78   2e-14
sp|Q5R5B6|PDIA1_PONPY  Protein disulfide-isomerase precursor...    78   2e-14
sp|Q9XI01|PDI1_ARATH  Probable protein disulfide-isomerase 1...    77   4e-14
sp|P54399|PDI_DROME  Protein disulfide-isomerase precursor (...    77   7e-14
sp|P80284|PDI_HORVU  Protein disulfide-isomerase precursor (...    77   7e-14
sp|P04785|PDIA1_RAT  Protein disulfide-isomerase precursor (...    76   9e-14
sp|Q5I0H9|PDIA5_RAT  Protein disulfide-isomerase A5 precursor      76   9e-14
sp|Q8R4U2|PDIA1_CRIGR  Protein disulfide-isomerase precursor...    76   9e-14
sp|P13667|PDIA4_HUMAN  Protein disulfide-isomerase A4 precur...    76   1e-13
>sp|P21195|PDIA1_RABIT Protein disulfide-isomerase precursor (PDI) (Prolyl 4-hydroxylase
           beta subunit) (Cellular thyroid hormone binding protein)
           (p55)
          Length = 509

 Score = 80.9 bits (198), Expect = 4e-15
 Identities = 45/109 (41%), Positives = 64/109 (58%), Gaps = 3/109 (2%)
 Frame = +1

Query: 175 VVILETSNFVQNIVSQKSGSFVMFYSPWCGHCVAMKPALVNAANKLHNLLPSCLVAAVDA 354
           V++L++SNF + + + K    V FY+PWCGHC A+ P    AA KL        +A VDA
Sbjct: 27  VLVLKSSNFAEELAAHKH-LLVEFYAPWCGHCKALAPEYAKAAGKLKAEGSDIRLAKVDA 85

Query: 355 TSETNLAAQYKVTGFPTIIYFSPSGDWV---KYVGERTEDAIVQFMMKK 492
           T E++LA QY V G+PTI +F  +GD     +Y   R  D IV ++ K+
Sbjct: 86  TEESDLAQQYGVRGYPTIKFFK-NGDTASPKEYTAGREADDIVNWLKKR 133

 Score = 60.8 bits (146), Expect = 4e-09
 Identities = 42/138 (30%), Positives = 64/138 (46%), Gaps = 5/138 (3%)
 Frame = +1

Query: 103 FMTNPPKPKLDARR---HWRRIPGHEAVVILETSNFVQNIVSQKSGSFVMFYSPWCGHCV 273
           F+    KP L ++     W R P    V +L   NF +    +K   FV FY+PWCGHC 
Sbjct: 347 FLEGKIKPHLMSQELPEDWDRQP----VKVLVGKNFEEVAFDEKKNVFVEFYAPWCGHCK 402

Query: 274 AMKPALVNAANKLHNLLPSCLVAAVDATSETNLAAQYKVTGFPTIIYF--SPSGDWVKYV 447
            + P + +   + +      ++A +D+T+  N     KV  FPT+ +F   P    + Y 
Sbjct: 403 QLAP-IWDKLGETYKEHQDIVIAKMDSTA--NEVEAVKVHSFPTLKFFPAGPGRTVIDYN 459

Query: 448 GERTEDAIVQFMMKKDSD 501
           GERT D   +F+     D
Sbjct: 460 GERTLDGFKKFLESGGQD 477
>sp|P07237|PDIA1_HUMAN Protein disulfide-isomerase precursor (PDI) (Prolyl 4-hydroxylase
           beta subunit) (Cellular thyroid hormone binding protein)
           (p55)
          Length = 508

 Score = 78.2 bits (191), Expect = 2e-14
 Identities = 45/109 (41%), Positives = 62/109 (56%), Gaps = 3/109 (2%)
 Frame = +1

Query: 175 VVILETSNFVQNIVSQKSGSFVMFYSPWCGHCVAMKPALVNAANKLHNLLPSCLVAAVDA 354
           V++L  SNF + + + K    V FY+PWCGHC A+ P    AA KL        +A VDA
Sbjct: 26  VLVLRKSNFAEALAAHKY-LLVEFYAPWCGHCKALAPEYAKAAGKLKAEGSEIRLAKVDA 84

Query: 355 TSETNLAAQYKVTGFPTIIYFSPSGDWV---KYVGERTEDAIVQFMMKK 492
           T E++LA QY V G+PTI +F  +GD     +Y   R  D IV ++ K+
Sbjct: 85  TEESDLAQQYGVRGYPTIKFFR-NGDTASPKEYTAGREADDIVNWLKKR 132

 Score = 61.6 bits (148), Expect = 2e-09
 Identities = 45/151 (29%), Positives = 70/151 (46%), Gaps = 5/151 (3%)
 Frame = +1

Query: 64  EYSLEREEDDFIAFMTNPPKPKLDARR---HWRRIPGHEAVVILETSNFVQNIVSQKSGS 234
           E + ER  +    F+    KP L ++     W + P    V +L   NF      +K   
Sbjct: 333 ELTAERITEFCHRFLEGKIKPHLMSQELPEDWDKQP----VKVLVGKNFEDVAFDEKKNV 388

Query: 235 FVMFYSPWCGHCVAMKPALVNAANKLHNLLPSCLVAAVDATSETNLAAQYKVTGFPTIIY 414
           FV FY+PWCGHC  + P + +   + +    + ++A +D+T+  N     KV  FPT+ +
Sbjct: 389 FVEFYAPWCGHCKQLAP-IWDKLGETYKDHENIVIAKMDSTA--NEVEAVKVHSFPTLKF 445

Query: 415 FSPSGD--WVKYVGERTEDAIVQFMMKKDSD 501
           F  S D   + Y GERT D   +F+     D
Sbjct: 446 FPASADRTVIDYNGERTLDGFKKFLESGGQD 476
>sp|Q5R5B6|PDIA1_PONPY Protein disulfide-isomerase precursor (PDI) (Prolyl 4-hydroxylase
           beta subunit)
          Length = 508

 Score = 78.2 bits (191), Expect = 2e-14
 Identities = 45/109 (41%), Positives = 62/109 (56%), Gaps = 3/109 (2%)
 Frame = +1

Query: 175 VVILETSNFVQNIVSQKSGSFVMFYSPWCGHCVAMKPALVNAANKLHNLLPSCLVAAVDA 354
           V++L  SNF + + + K    V FY+PWCGHC A+ P    AA KL        +A VDA
Sbjct: 26  VLVLRKSNFAEALAAHKY-LLVEFYAPWCGHCKALAPEYAKAAGKLKAEGSEIRLAKVDA 84

Query: 355 TSETNLAAQYKVTGFPTIIYFSPSGDWV---KYVGERTEDAIVQFMMKK 492
           T E++LA QY V G+PTI +F  +GD     +Y   R  D IV ++ K+
Sbjct: 85  TEESDLAQQYGVRGYPTIKFFR-NGDTASPKEYTAGREADDIVNWLKKR 132

 Score = 61.6 bits (148), Expect = 2e-09
 Identities = 45/151 (29%), Positives = 70/151 (46%), Gaps = 5/151 (3%)
 Frame = +1

Query: 64  EYSLEREEDDFIAFMTNPPKPKLDARR---HWRRIPGHEAVVILETSNFVQNIVSQKSGS 234
           E + ER  +    F+    KP L ++     W + P    V +L   NF      +K   
Sbjct: 333 ELTAERITEFCHRFLEGKIKPHLMSQELPDDWDKQP----VKVLVGKNFEDVAFDEKKNV 388

Query: 235 FVMFYSPWCGHCVAMKPALVNAANKLHNLLPSCLVAAVDATSETNLAAQYKVTGFPTIIY 414
           FV FY+PWCGHC  + P + +   + +    + ++A +D+T+  N     KV  FPT+ +
Sbjct: 389 FVEFYAPWCGHCKQLAP-IWDKLGETYKDHENIVIAKMDSTA--NEVEAVKVHSFPTLKF 445

Query: 415 FSPSGD--WVKYVGERTEDAIVQFMMKKDSD 501
           F  S D   + Y GERT D   +F+     D
Sbjct: 446 FPASADRTVIDYNGERTLDGFKKFLESGGQD 476
>sp|Q9XI01|PDI1_ARATH Probable protein disulfide-isomerase 1 precursor (PDI 1)
          Length = 501

 Score = 77.4 bits (189), Expect = 4e-14
 Identities = 45/118 (38%), Positives = 65/118 (55%), Gaps = 3/118 (2%)
 Frame = +1

Query: 169 EAVVILETSNFVQNIVSQKSGSFVMFYSPWCGHCVAMKPALVNAANKLHNLLPSCLVAAV 348
           E V+ L+ +NF   I ++     V FY+PWCGHC  + P    AA+ L + +P  ++A +
Sbjct: 30  EFVLTLDHTNFTDTI-NKHDFIVVEFYAPWCGHCKQLAPEYEKAASALSSNVPPVVLAKI 88

Query: 349 DATSETN--LAAQYKVTGFPTIIYFSPSGDWV-KYVGERTEDAIVQFMMKKDSDLKYE 513
           DA+ ETN   A QY+V GFPTI  F   G  V +Y G R  + IV ++ K+      E
Sbjct: 89  DASEETNREFATQYEVQGFPTIKIFRNGGKAVQEYNGpreAEGIVTYLKKQSGPASAE 146

 Score = 65.1 bits (157), Expect = 2e-10
 Identities = 38/122 (31%), Positives = 63/122 (51%), Gaps = 4/122 (3%)
 Frame = +1

Query: 166 HEAVVILETSNFVQNIVSQKSGSFVMFYSPWCGHCVAMKPALVNAANKLHNLLPSCLVAA 345
           +E V ++ + +    +++      + FY+PWCGHC  + P L   A    +   S ++A 
Sbjct: 373 NEPVKVVVSDSLDDIVLNSGKNVLLEFYAPWCGHCQKLAPILDEVAVSYQSD-SSVVIAK 431

Query: 346 VDATSETNLAAQYKVTGFPTIIYFSPSGDWVKYVGERTEDAIVQFMMKKDSDL----KYE 513
           +DAT+       + V GFPTI + S SG+ V Y G+RT++  + F+ K    +    K E
Sbjct: 432 LDATANDFPKDTFDVKGFPTIYFKSASGNVVVYEGDRTKEDFISFVDKNKDTVGEPKKEE 491

Query: 514 ET 519
           ET
Sbjct: 492 ET 493
>sp|P54399|PDI_DROME Protein disulfide-isomerase precursor (PDI)
          Length = 496

 Score = 76.6 bits (187), Expect = 7e-14
 Identities = 43/108 (39%), Positives = 59/108 (54%)
 Frame = +1

Query: 169 EAVVILETSNFVQNIVSQKSGSFVMFYSPWCGHCVAMKPALVNAANKLHNLLPSCLVAAV 348
           E V++    NF Q +++      V FY+PWCGHC A+ P    AA +L        +A V
Sbjct: 27  EGVLVATVDNFKQ-LIADNEFVLVEFYAPWCGHCKALAPEYAKAAQQLAEKESPIKLAKV 85

Query: 349 DATSETNLAAQYKVTGFPTIIYFSPSGDWVKYVGERTEDAIVQFMMKK 492
           DAT E  LA QY V G+PT+ +F  SG  V+Y G R    I+ ++ KK
Sbjct: 86  DATVEGELAEQYAVRGYPTLKFFR-SGSPVEYSGGRQAADIIAWVTKK 132

 Score = 55.1 bits (131), Expect = 2e-07
 Identities = 34/104 (32%), Positives = 53/104 (50%), Gaps = 1/104 (0%)
 Frame = +1

Query: 175 VVILETSNFVQNIVSQKSGSFVMFYSPWCGHCVAMKPALVNAANKLHNLLPSCLVAAVDA 354
           V +L +SNF    + +     V FY+PWCGHC  + P     A K  +     ++A +D+
Sbjct: 369 VKVLVSSNFESVALDKSKSVLVEFYAPWCGHCKQLAPIYDQLAEKYKD-NEDIVIAKMDS 427

Query: 355 TSETNLAAQYKVTGFPTIIYFSPSGDWV-KYVGERTEDAIVQFM 483
           T+  N     K++ FPTI YF    + V  +  +RT D  V+F+
Sbjct: 428 TA--NELESIKISSFPTIKYFRKEDNKVIDFNLDRTLDDFVKFL 469
>sp|P80284|PDI_HORVU Protein disulfide-isomerase precursor (PDI) (Endosperm protein E-1)
          Length = 513

 Score = 76.6 bits (187), Expect = 7e-14
 Identities = 45/135 (33%), Positives = 69/135 (51%), Gaps = 3/135 (2%)
 Frame = +1

Query: 97  IAFMTNPPKPKLDARRHWRRIPGHEAVVILETSNFVQNIVSQKSGSFVMFYSPWCGHCVA 276
           +A + + P  + +           EAV+ L   NF  + + Q     V FY+PWCGHC +
Sbjct: 14  LAVVLSAPAARAEEAAAAEEAAAPEAVLTLHADNF-DDAIGQHPFILVEFYAPWCGHCKS 72

Query: 277 MKPALVNAANKLHNLLPSCLVAAVDATSETN--LAAQYKVTGFPTIIYFSPSGDWV-KYV 447
           + P    AA  L    P+ ++A VDA  E N  LA +Y+V GFPT+  F   G  + +Y 
Sbjct: 73  LAPEYEKAAQLLSKHDPAIVLAKVDANDEKNKPLAGKYEVQGFPTLKIFRNGGKSIQEYK 132

Query: 448 GERTEDAIVQFMMKK 492
           G R  + IV+++ K+
Sbjct: 133 GpreAEGIVEYLKKQ 147

 Score = 73.2 bits (178), Expect = 8e-13
 Identities = 44/138 (31%), Positives = 69/138 (50%), Gaps = 2/138 (1%)
 Frame = +1

Query: 82  EEDDFIAFMTNPPKPKLDARRHWRRIP--GHEAVVILETSNFVQNIVSQKSGSFVMFYSP 255
           E    +A++ +    KL   R    IP   +E V ++   N    +        + FY+P
Sbjct: 350 EAGQIVAWLKDYFDGKLTPFRKSEPIPEANNEPVKVVVADNVHDVVFKSGKNVLIEFYAP 409

Query: 256 WCGHCVAMKPALVNAANKLHNLLPSCLVAAVDATSETNLAAQYKVTGFPTIIYFSPSGDW 435
           WCGHC  + P L  AA  L +     ++A +DAT E ++  ++ V G+PT+ + +PSG  
Sbjct: 410 WCGHCKKLAPILDEAAATLQSE-EDVVIAKMDAT-ENDVPGEFDVQGYPTLYFVTPSGKK 467

Query: 436 VKYVGERTEDAIVQFMMK 489
           V Y G RT D IV ++ K
Sbjct: 468 VSYEGGRTADEIVDYIRK 485
>sp|P04785|PDIA1_RAT Protein disulfide-isomerase precursor (PDI) (Prolyl 4-hydroxylase
           beta subunit) (Cellular thyroid hormone binding protein)
          Length = 509

 Score = 76.3 bits (186), Expect = 9e-14
 Identities = 44/109 (40%), Positives = 62/109 (56%), Gaps = 3/109 (2%)
 Frame = +1

Query: 175 VVILETSNFVQNIVSQKSGSFVMFYSPWCGHCVAMKPALVNAANKLHNLLPSCLVAAVDA 354
           V++L+ SNF + + +      V FY+PWCGHC A+ P    AA KL        +A VDA
Sbjct: 28  VLVLKKSNFAEALAAHNY-LLVEFYAPWCGHCKALAPEYAKAAAKLKAEGSEIRLAKVDA 86

Query: 355 TSETNLAAQYKVTGFPTIIYFSPSGDWV---KYVGERTEDAIVQFMMKK 492
           T E++LA QY V G+PTI +F  +GD     +Y   R  D IV ++ K+
Sbjct: 87  TEESDLAQQYGVRGYPTIKFFK-NGDTASPKEYTAGREADDIVNWLKKR 134

 Score = 61.2 bits (147), Expect = 3e-09
 Identities = 42/138 (30%), Positives = 66/138 (47%), Gaps = 5/138 (3%)
 Frame = +1

Query: 103 FMTNPPKPKLDARR---HWRRIPGHEAVVILETSNFVQNIVSQKSGSFVMFYSPWCGHCV 273
           F+    KP L ++     W + P    V +L   NF +    +K   FV FY+PWCGHC 
Sbjct: 348 FLEGKIKPHLMSQELPEDWDKQP----VKVLVGKNFEEVAFDEKKNVFVEFYAPWCGHCK 403

Query: 274 AMKPALVNAANKLHNLLPSCLVAAVDATSETNLAAQYKVTGFPTIIYFSPSGD--WVKYV 447
            + P + +   + +    + ++A +D+T+  N     KV  FPT+ +F  S D   + Y 
Sbjct: 404 QLAP-IWDKLGETYKDHENIVIAKMDSTA--NEVEAVKVHSFPTLKFFPASADRTVIDYN 460

Query: 448 GERTEDAIVQFMMKKDSD 501
           GERT D   +F+     D
Sbjct: 461 GERTLDGFKKFLESGGQD 478
>sp|Q5I0H9|PDIA5_RAT Protein disulfide-isomerase A5 precursor
          Length = 517

 Score = 76.3 bits (186), Expect = 9e-14
 Identities = 53/168 (31%), Positives = 82/168 (48%), Gaps = 2/168 (1%)
 Frame = +1

Query: 22  IFRYFNYGKNTSYSEYSLEREEDDFIAFMTNPPKPKLDA-RRHWRRIPGHEAVVILETSN 198
           +F+Y NYG              +D + ++ NP  P+       W    G  +V  L   +
Sbjct: 237 LFQYENYGSTA-----------EDIVEWLKNPQPPQPQVPETPWADEGG--SVYHLTDED 283

Query: 199 FVQNIVSQKSGSFVMFYSPWCGHCVAMKPALVNAANKLH-NLLPSCLVAAVDATSETNLA 375
           F Q  V + S   VMF++PWCGHC  MKP   +AA  LH +   S ++AAVDAT    LA
Sbjct: 284 FDQ-FVKEHSSVLVMFHAPWCGHCKKMKPEFESAAEVLHGDAESSGVLAAVDATINEALA 342

Query: 376 AQYKVTGFPTIIYFSPSGDWVKYVGERTEDAIVQFMMKKDSDLKYEET 519
            ++ ++ FPT+ YF  +G+       RT+   +++M   ++    E T
Sbjct: 343 ERFHISAFPTLKYFK-NGEQQAVPALRTKKKFIEWMQNPEAPPPPEPT 389

 Score = 59.3 bits (142), Expect = 1e-08
 Identities = 50/172 (29%), Positives = 73/172 (42%), Gaps = 3/172 (1%)
 Frame = +1

Query: 19  PIFRYFNYGKNTSYSEYSLEREEDDFIAFMTNPPKPKLDARRHWRRIPGHEAVVILETSN 198
           P  +YF  G+  +       R +  FI +M NP  P       W       +V+ L   N
Sbjct: 351 PTLKYFKNGEQQAVPAL---RTKKKFIEWMQNPEAPP-PPEPTWEE--QQTSVLHLVGDN 404

Query: 199 FVQNIVSQKSGSFVMFYSPWCGHCVAMKPALVNAANKLHNLLPSCLVAAVDATSETN--L 372
           F + +  +K  + VMFY+PWC HC  + P     A+   +       AAVD   + N  L
Sbjct: 405 FRETL-KKKKHTLVMFYAPWCPHCKKVIPHFTATADAFKD-DRKIACAAVDCVKDKNQDL 462

Query: 373 AAQYKVTGFPTIIYFSPSGDWVKYVGERTEDAIVQFMMK-KDSDLKYEETQR 525
             Q  V  +PT  Y+       KY  +RTE     F+   ++ DLK  E +R
Sbjct: 463 CQQESVKAYPTFHYYHYGKLVEKYESDRTELGFTSFIRTLREGDLKRLEKRR 514

 Score = 58.9 bits (141), Expect = 2e-08
 Identities = 41/158 (25%), Positives = 69/158 (43%), Gaps = 5/158 (3%)
 Frame = +1

Query: 13  EDPIFRYFNYGKNTSYSEYSLEREEDDFIAFMTNPPKPKLDARRHWRRIPGHEAVVILET 192
           +D     F+Y     + +Y         +AF+ +P  P L     W   PG + VV +++
Sbjct: 102 KDKKIELFHYQDGAFHMQYDRAVTLKSIVAFLKDPKGPPL-----WEEDPGAKDVVHIDS 156

Query: 193 S-NFVQNIVSQKSGSFVMFYSPWCGHCVAMKPALVNAANKL--HNLLPSCLVAAVDATSE 363
             +F + +  ++    +MFY+PWC  C  + P    AA ++  H +L    V   +    
Sbjct: 157 EKDFRRLLKKEEKPLLMMFYAPWCSMCKRIMPHFQKAATQVRGHTVLAGMNVYPPEF--- 213

Query: 364 TNLAAQYKVTGFPTIIYFSPSGDWVKY--VGERTEDAI 471
            N+  +Y V G+PTI YF       +Y   G   ED +
Sbjct: 214 ENIKEEYNVRGYPTICYFEKGRFLFQYENYGSTAEDIV 251
>sp|Q8R4U2|PDIA1_CRIGR Protein disulfide-isomerase precursor (PDI) (Prolyl 4-hydroxylase
           beta subunit) (p58)
          Length = 509

 Score = 76.3 bits (186), Expect = 9e-14
 Identities = 44/109 (40%), Positives = 62/109 (56%), Gaps = 3/109 (2%)
 Frame = +1

Query: 175 VVILETSNFVQNIVSQKSGSFVMFYSPWCGHCVAMKPALVNAANKLHNLLPSCLVAAVDA 354
           V++L+ SNF + + +      V FY+PWCGHC A+ P    AA KL        +A VDA
Sbjct: 28  VLVLKKSNFAEALAAHNY-LLVEFYAPWCGHCKALAPEYAKAAAKLKAEGSEIRLAKVDA 86

Query: 355 TSETNLAAQYKVTGFPTIIYFSPSGDWV---KYVGERTEDAIVQFMMKK 492
           T E++LA QY V G+PTI +F  +GD     +Y   R  D IV ++ K+
Sbjct: 87  TEESDLAQQYGVRGYPTIKFFK-NGDTASPKEYTAGREADDIVNWLKKR 134

 Score = 60.5 bits (145), Expect = 5e-09
 Identities = 41/138 (29%), Positives = 66/138 (47%), Gaps = 5/138 (3%)
 Frame = +1

Query: 103 FMTNPPKPKLDARR---HWRRIPGHEAVVILETSNFVQNIVSQKSGSFVMFYSPWCGHCV 273
           F+    KP L ++     W + P    V +L   NF +    +K   FV FY+PWCGHC 
Sbjct: 348 FLEGKIKPHLMSQELPEDWDKQP----VKVLVGKNFEEVAFDEKKNVFVEFYAPWCGHCK 403

Query: 274 AMKPALVNAANKLHNLLPSCLVAAVDATSETNLAAQYKVTGFPTIIYFSPSGD--WVKYV 447
            + P + +   + +    + ++A +D+T+  N     KV  FPT+ +F  + D   + Y 
Sbjct: 404 QLAP-IWDKLGETYKDHENIIIAKMDSTA--NEVEAVKVHSFPTLKFFPATADRTVIDYN 460

Query: 448 GERTEDAIVQFMMKKDSD 501
           GERT D   +F+     D
Sbjct: 461 GERTLDGFKKFLESGGQD 478
>sp|P13667|PDIA4_HUMAN Protein disulfide-isomerase A4 precursor (Protein ERp-72) (ERp72)
          Length = 645

 Score = 75.9 bits (185), Expect = 1e-13
 Identities = 46/143 (32%), Positives = 73/143 (51%)
 Frame = +1

Query: 64  EYSLEREEDDFIAFMTNPPKPKLDARRHWRRIPGHEAVVILETSNFVQNIVSQKSGSFVM 243
           +Y   R +++ +A +    +P       W   P  E  ++L   NF   +V+      V 
Sbjct: 150 DYEGSRTQEEIVAKVREVSQPD------WT--PPPEVTLVLTKENF-DEVVNDADIILVE 200

Query: 244 FYSPWCGHCVAMKPALVNAANKLHNLLPSCLVAAVDATSETNLAAQYKVTGFPTIIYFSP 423
           FY+PWCGHC  + P    AA +L    P   +A VDAT+ET+LA ++ V+G+PT+  F  
Sbjct: 201 FYAPWCGHCKKLAPEYEKAAKELSKRSPPIPLAKVDATAETDLAKRFDVSGYPTLKIFR- 259

Query: 424 SGDWVKYVGERTEDAIVQFMMKK 492
            G    Y G R +  IV +M+++
Sbjct: 260 KGRPYDYNGpreKYGIVDYMIEQ 282

 Score = 75.1 bits (183), Expect = 2e-13
 Identities = 47/133 (35%), Positives = 64/133 (48%)
 Frame = +1

Query: 76  EREEDDFIAFMTNPPKPKLDARRHWRRIPGHEAVVILETSNFVQNIVSQKSGSFVMFYSP 255
           E EEDD             D       +     V++L  +NF  N V+ K    + FY+P
Sbjct: 44  EEEEDD-------------DEEEDDLEVKEENGVLVLNDANF-DNFVADKDTVLLEFYAP 89

Query: 256 WCGHCVAMKPALVNAANKLHNLLPSCLVAAVDATSETNLAAQYKVTGFPTIIYFSPSGDW 435
           WCGHC    P     AN L +  P   VA +DATS + LA+++ V+G+PTI      G  
Sbjct: 90  WCGHCKQFAPEYEKIANILKDKDPPIPVAKIDATSASVLASRFDVSGYPTIKILK-KGQA 148

Query: 436 VKYVGERTEDAIV 474
           V Y G RT++ IV
Sbjct: 149 VDYEGSRTQEEIV 161

 Score = 67.0 bits (162), Expect = 6e-11
 Identities = 43/133 (32%), Positives = 71/133 (53%), Gaps = 7/133 (5%)
 Frame = +1

Query: 55  SYSEYSLEREEDD-------FIAFMTNPPKPKLDARRHWRRIPGHEAVVILETSNFVQNI 213
           S  ++++E EE D         AF     KP + ++   +   G   VV+ +T + +  +
Sbjct: 482 SGKKFAMEPEEFDSDTLREFVTAFKKGKLKPVIKSQPVPKNNKGPVKVVVGKTFDSI--V 539

Query: 214 VSQKSGSFVMFYSPWCGHCVAMKPALVNAANKLHNLLPSCLVAAVDATSETNLAAQYKVT 393
           +  K    + FY+PWCGHC  ++P + N+  K +      ++A +DAT+    + +YKV 
Sbjct: 540 MDPKKDVLIEFYAPWCGHCKQLEP-VYNSLAKKYKGQKGLVIAKMDATANDVPSDRYKVE 598

Query: 394 GFPTIIYFSPSGD 432
           GFPT IYF+PSGD
Sbjct: 599 GFPT-IYFAPSGD 610
  Database: Non-redundant SwissProt sequences
    Posted date:  Dec 6, 2005  7:40 AM
  Number of letters in database: 68,354,980
  Number of sequences in database:  184,735
  
  Database: swissprot.01
    Posted date:  Dec 6, 2005  8:18 AM
  Number of letters in database: 66,202,850
  Number of sequences in database:  184,431
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 66,754,594
Number of Sequences: 369166
Number of extensions: 1372370
Number of successful extensions: 3628
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3365
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3522
length of database: 68,354,980
effective HSP length: 108
effective length of database: 48,403,600
effective search space used: 7405750800
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)