Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_015_G12
(779 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9NRA2|S17A5_HUMAN Sialin (Solute carrier family 17 memb... 193 5e-49
sp|Q9MZD1|S17A5_SHEEP Sialin (Solute carrier family 17 memb... 192 9e-49
sp|Q8BN82|S17A5_MOUSE Sialin (Solute carrier family 17 memb... 191 2e-48
sp|Q03567|YLD2_CAEEL Hypothetical protein C38C10.2 in chrom... 168 2e-41
sp|O61369|PICO_DROAN Putative inorganic phosphate cotranspo... 162 1e-39
sp|Q9V7S5|PICO_DROME Putative inorganic phosphate cotranspo... 159 6e-39
sp|P34644|YOQ6_CAEEL Hypothetical protein ZK512.6 in chromo... 159 1e-38
sp|Q61983|NPT1_MOUSE Renal sodium-dependent phosphate trans... 142 8e-34
sp|Q62795|NPT1_RAT Renal sodium-dependent phosphate transpo... 142 1e-33
sp|Q14916|NPT1_HUMAN Renal sodium-dependent phosphate trans... 139 9e-33
>sp|Q9NRA2|S17A5_HUMAN Sialin (Solute carrier family 17 member 5) (Sodium/sialic acid
cotransporter) (AST) (Membrane glycoprotein HP59)
Length = 495
Score = 193 bits (490), Expect = 5e-49
Identities = 101/246 (41%), Positives = 148/246 (60%), Gaps = 2/246 (0%)
Frame = +2
Query: 41 GYGWLIALRVLEGAGESITYPAMHTMLGYWAPAMETTFIGGIVYSGSFXXXXXXXXXXXX 220
G G LI LR LEG GE +T+PAMH M WAP +E + + I Y+G+
Sbjct: 160 GVGPLIVLRALEGLGEGVTFPAMHAMWSSWAPPLERSKLLSISYAGAQLGTVISLPLSGI 219
Query: 221 XXDANVMGGWPSVFYIPGIVGVLWFIIWSFVAYSTPAHHPRISEKEKRFIESSVN--LSA 394
W VFY G +G+ WF++W ++ TP H RIS EK +I SS+ LS+
Sbjct: 220 IC---YYMNWTYVFYFFGTIGIFWFLLWIWLVSDTPQKHKRISHYEKEYILSSLRNQLSS 276
Query: 395 EEKHTNVPWKQIMLSVPVWAISIANFCAMWSLYTLLTSLPQFFEYVLGFSISENGYINAL 574
++ +VPW I+ S+P+WAI +A+F W+ YTLLT LP + + +L F++ ENG++++L
Sbjct: 277 QK---SVPWVPILKSLPLWAIVVAHFSYNWTFYTLLTLLPTYMKEILRFNVQENGFLSSL 333
Query: 575 PYFLSAITFVLSGKLADIIRSRKWMSTTVTRKLFNTIGMLVNAIFIVAISFIGCDKVLVV 754
PY S + +LSG+ AD +R++ ST R++F+ IGM+ A+F+VA FIGCD L V
Sbjct: 334 PYLGSWLCMILSGQAADNLRAKWNFSTLCVRRIFSLIGMIGPAVFLVAAGFIGCDYSLAV 393
Query: 755 TFLCIA 772
FL I+
Sbjct: 394 AFLTIS 399
>sp|Q9MZD1|S17A5_SHEEP Sialin (Solute carrier family 17 member 5) (Sodium/sialic acid
cotransporter) (Membrane glycoprotein SP55)
Length = 495
Score = 192 bits (488), Expect = 9e-49
Identities = 105/246 (42%), Positives = 148/246 (60%), Gaps = 2/246 (0%)
Frame = +2
Query: 41 GYGWLIALRVLEGAGESITYPAMHTMLGYWAPAMETTFIGGIVYSGSFXXXXXXXXXXXX 220
G G L+ALR LEG GE +TYPAMH M WAP +E + + I Y+G+
Sbjct: 160 GVGALVALRALEGLGEGVTYPAMHAMWSSWAPPLERSKLLSISYAGAQLGTVVSLPLSGV 219
Query: 221 XXDANVMGGWPSVFYIPGIVGVLWFIIWSFVAYSTPAHHPRISEKEKRFIESSVN--LSA 394
W VFY GIVG++WFI+W + TP H I+ EK +I SS+ LS+
Sbjct: 220 IC---YYMNWTYVFYFFGIVGIIWFILWICLVSDTPETHKTITPYEKEYILSSLKNQLSS 276
Query: 395 EEKHTNVPWKQIMLSVPVWAISIANFCAMWSLYTLLTSLPQFFEYVLGFSISENGYINAL 574
++ +VPW ++ S+P+WAI +A+F W+ YTLLT LP + + VL F+I ENG+++A+
Sbjct: 277 QK---SVPWIPMLKSLPLWAIVVAHFSYNWTFYTLLTLLPTYMKEVLRFNIQENGFLSAV 333
Query: 575 PYFLSAITFVLSGKLADIIRSRKWMSTTVTRKLFNTIGMLVNAIFIVAISFIGCDKVLVV 754
PY + +LSG+ AD +R+R ST R++F+ IGM+ AIF+VA FIGCD L V
Sbjct: 334 PYLGCWLCMILSGQAADNLRARWNFSTLWVRRVFSLIGMIGPAIFLVAAGFIGCDYSLAV 393
Query: 755 TFLCIA 772
FL I+
Sbjct: 394 AFLTIS 399
>sp|Q8BN82|S17A5_MOUSE Sialin (Solute carrier family 17 member 5) (Sodium/sialic acid
cotransporter)
Length = 495
Score = 191 bits (485), Expect = 2e-48
Identities = 98/240 (40%), Positives = 141/240 (58%)
Frame = +2
Query: 53 LIALRVLEGAGESITYPAMHTMLGYWAPAMETTFIGGIVYSGSFXXXXXXXXXXXXXXDA 232
L+ LR LEG GE +T+PAMH M WAP +E + + I Y+G+
Sbjct: 164 LVVLRALEGLGEGVTFPAMHAMWSSWAPPLERSKLLTISYAGAQLGTVISLPLSGIIC-- 221
Query: 233 NVMGGWPSVFYIPGIVGVLWFIIWSFVAYSTPAHHPRISEKEKRFIESSVNLSAEEKHTN 412
W VFY+ GIVG++WFI+W ++ TP H IS EK +I SS+ +
Sbjct: 222 -YYMNWTYVFYLFGIVGIVWFILWMWIVSDTPETHKTISHYEKEYIVSSLKNQLSSQKV- 279
Query: 413 VPWKQIMLSVPVWAISIANFCAMWSLYTLLTSLPQFFEYVLGFSISENGYINALPYFLSA 592
VPW I+ S+P+WAI +A+F WS YTLLT LP + + +L F++ ENG+++ALPYF
Sbjct: 280 VPWGSILKSLPLWAIVVAHFSYNWSFYTLLTLLPTYMKEILRFNVQENGFLSALPYFGCW 339
Query: 593 ITFVLSGKLADIIRSRKWMSTTVTRKLFNTIGMLVNAIFIVAISFIGCDKVLVVTFLCIA 772
+ +L G+ AD +R + ST R++F+ +GM+ A+F+VA FIGCD L V FL I+
Sbjct: 340 LCMILCGQAADYLRVKWNFSTISVRRIFSLVGMVGPAVFLVAAGFIGCDYSLAVAFLTIS 399
>sp|Q03567|YLD2_CAEEL Hypothetical protein C38C10.2 in chromosome III
Length = 493
Score = 168 bits (425), Expect = 2e-41
Identities = 88/246 (35%), Positives = 134/246 (54%), Gaps = 4/246 (1%)
Frame = +2
Query: 53 LIALRVLEGAGESITYPAMHTMLGYWAPAMETTFIGGIVYSGSFXXXXXXXXXXXXXXDA 232
L LR G + T+PAMHTM W P +E + + G+ Y+G+ +
Sbjct: 139 LAILRAAIGFLQGATFPAMHTMWSVWGPPLELSVLTGVTYAGAQIGNVIVLPLSGFLCEY 198
Query: 233 NVMGGWPSVFYIPGIVGVLWFIIWSFVAYSTPAHHPRISEKEKRFIESSVNLSAEE---K 403
GGWPS+FYI G+ GVLW +W +V+ PA HPRI+ +EK++I ++V S + K
Sbjct: 199 GFDGGWPSIFYIIGVFGVLWTAVWWYVSSDKPATHPRITPEEKQYIVTAVEASMGKDTGK 258
Query: 404 HTNVPWKQIMLSVPVWAISIANFCAMWSLYTLLTSLPQFFEYVLGFSISENGYINALPYF 583
+ PW +I+ S VWA +F W YT+L SLP F + VLG ++S G + ++PY
Sbjct: 259 VPSTPWIKILTSPAVWACWAGHFAGDWGAYTMLVSLPSFLKDVLGLNLSSLGAVASIPYI 318
Query: 584 LSAITFVLSGKLADIIRSRKWMSTTVTRKLFNTIGMLVNAIFIVAISFIGCDK-VLVVTF 760
+ G LAD +RS+ +ST TR+ + ++ IF+VA + GC + VLV+ F
Sbjct: 319 AYFLAINAGGVLADTLRSKGILSTLNTRRAAMLVALIGQGIFLVASGYCGCGQDVLVIIF 378
Query: 761 LCIAVA 778
+ +A
Sbjct: 379 ITCGMA 384
>sp|O61369|PICO_DROAN Putative inorganic phosphate cotransporter
Length = 483
Score = 162 bits (409), Expect = 1e-39
Identities = 87/248 (35%), Positives = 132/248 (53%), Gaps = 1/248 (0%)
Frame = +2
Query: 35 RAGYGW-LIALRVLEGAGESITYPAMHTMLGYWAPAMETTFIGGIVYSGSFXXXXXXXXX 211
R G W L A+R ++G GE P H ML W P E + +G VY+G+
Sbjct: 112 REGGVWGLCAVRFIQGLGEGPIVPCTHAMLAKWIPPNERSRMGAAVYAGAQFGTIISMPL 171
Query: 212 XXXXXDANVMGGWPSVFYIPGIVGVLWFIIWSFVAYSTPAHHPRISEKEKRFIESSVNLS 391
+ GGWPS+FY+ GIVG +W I + Y P+ HP+I E+EK++I S+ +
Sbjct: 172 SGLLAEYGFDGGWPSIFYVFGIVGTVWSIAFLIFVYEDPSTHPKIDEREKKYINESLWGT 231
Query: 392 AEEKHTNVPWKQIMLSVPVWAISIANFCAMWSLYTLLTSLPQFFEYVLGFSISENGYINA 571
K +P+K I+ S+P +AI A+ + TL+T LP + + VL FS+ NG +++
Sbjct: 232 DVIKSPPIPFKSIVKSLPFYAILFAHMGHNYGYETLMTELPTYMKQVLRFSLKSNGLLSS 291
Query: 572 LPYFLSAITFVLSGKLADIIRSRKWMSTTVTRKLFNTIGMLVNAIFIVAISFIGCDKVLV 751
LPY + + +AD + S K S T TRK+ N+IG + ++A S+ GCD+ L
Sbjct: 292 LPYLAMWLLSMFISVIADWMISSKRFSLTATRKIINSIGQYGPGLALIAASYTGCDRALT 351
Query: 752 VTFLCIAV 775
+ L I V
Sbjct: 352 LAILTIGV 359
>sp|Q9V7S5|PICO_DROME Putative inorganic phosphate cotransporter
Length = 529
Score = 159 bits (403), Expect = 6e-39
Identities = 87/248 (35%), Positives = 131/248 (52%), Gaps = 1/248 (0%)
Frame = +2
Query: 35 RAGYGW-LIALRVLEGAGESITYPAMHTMLGYWAPAMETTFIGGIVYSGSFXXXXXXXXX 211
R G W L A+R ++G GE P H ML W P E + +G VY+G+
Sbjct: 158 RGGGVWGLCAVRFIQGLGEGPIVPCTHAMLAKWIPPNERSRMGAAVYAGAQFGTIISMPL 217
Query: 212 XXXXXDANVMGGWPSVFYIPGIVGVLWFIIWSFVAYSTPAHHPRISEKEKRFIESSVNLS 391
+ GGWPS+FY+ GIVG +W I + + P+ HP I E+EK++I S+ +
Sbjct: 218 SGLLAEYGFDGGWPSIFYVFGIVGTVWSIAFLIFVHEDPSSHPTIDEREKKYINDSLWGT 277
Query: 392 AEEKHTNVPWKQIMLSVPVWAISIANFCAMWSLYTLLTSLPQFFEYVLGFSISENGYINA 571
K +P+K I+ S+P +AI A+ + TL+T LP + + VL FS+ NG +++
Sbjct: 278 DVVKSPPIPFKAIIKSLPFYAILFAHMGHNYGYETLMTELPTYMKQVLRFSLKSNGLLSS 337
Query: 572 LPYFLSAITFVLSGKLADIIRSRKWMSTTVTRKLFNTIGMLVNAIFIVAISFIGCDKVLV 751
LPY + + +AD + S K S T TRKL N+IG + ++A S+ GCD+ L
Sbjct: 338 LPYLAMWLFSMFISVVADWMISSKRFSHTATRKLINSIGQYGPGVALIAASYTGCDRALT 397
Query: 752 VTFLCIAV 775
+ L I V
Sbjct: 398 LAILTIGV 405
>sp|P34644|YOQ6_CAEEL Hypothetical protein ZK512.6 in chromosome III
Length = 576
Score = 159 bits (401), Expect = 1e-38
Identities = 79/241 (32%), Positives = 133/241 (55%), Gaps = 3/241 (1%)
Frame = +2
Query: 50 WLIA-LRVLEGAGESITYPAMHTMLGYWAPAMETTFIGGIVYSGSFXXXXXXXXXXXXXX 226
+L+A +++ +G + + YPAMH + YWAP ME + + ++GS+
Sbjct: 175 YLVAFIQITQGLVQGVCYPAMHGVWRYWAPPMERSKLATTAFTGSYAGAVLGLPLSAFLV 234
Query: 227 DANVMGGWPSVFYIPGIVGVLWFIIWSFVAYSTPAHHPRISEKEKRFIESSVNLSAEEKH 406
W + FY+ G+ GV+W I+W V + PA HP IS++EK FIE ++ +
Sbjct: 235 S---YVSWAAPFYLYGVCGVIWAILWFCVTFEKPAFHPTISQEEKIFIEDAIGHVSNTHP 291
Query: 407 T--NVPWKQIMLSVPVWAISIANFCAMWSLYTLLTSLPQFFEYVLGFSISENGYINALPY 580
T ++PWK I+ S PVWAI +ANF W+ Y LL + + + LG I+++G + A+P+
Sbjct: 292 TIRSIPWKAIVTSKPVWAIIVANFARSWTFYLLLQNQLTYMKEALGMKIADSGLLAAIPH 351
Query: 581 FLSAITFVLSGKLADIIRSRKWMSTTVTRKLFNTIGMLVNAIFIVAISFIGCDKVLVVTF 760
+ ++ G+LAD +RS K +STT RK+FN G A F++ +++ D ++
Sbjct: 352 LVMGCVVLMGGQLADYLRSNKILSTTAVRKIFNCGGFGGEAAFMLIVAYTTSDTTAIMAL 411
Query: 761 L 763
+
Sbjct: 412 I 412
>sp|Q61983|NPT1_MOUSE Renal sodium-dependent phosphate transport protein 1
(Sodium/phosphate cotransporter 1) (Na(+)/PI
cotransporter 1) (Renal sodium-phosphate transport
protein 1) (Renal Na(+)-dependent phosphate
cotransporter 1) (Solute carrier family 18 member 1)
Length = 465
Score = 142 bits (359), Expect = 8e-34
Identities = 80/246 (32%), Positives = 125/246 (50%)
Frame = +2
Query: 35 RAGYGWLIALRVLEGAGESITYPAMHTMLGYWAPAMETTFIGGIVYSGSFXXXXXXXXXX 214
+ G +I RVL+G + H + WAP +E + + SG
Sbjct: 128 QVGAALVIVCRVLQGIAQGTVSTGQHEIWVKWAPPLERGRLTSMTLSGFVMGPFIVLLVS 187
Query: 215 XXXXDANVMGGWPSVFYIPGIVGVLWFIIWSFVAYSTPAHHPRISEKEKRFIESSVNLSA 394
D + GWP VFYI GIVG + + W F+ + P HP +S EK +I SS+ A
Sbjct: 188 GFICD---LLGWPMVFYIFGIVGCVLSLSWFFLFFDDPKDHPYMSSSEKDYIISSLMQQA 244
Query: 395 EEKHTNVPWKQIMLSVPVWAISIANFCAMWSLYTLLTSLPQFFEYVLGFSISENGYINAL 574
++P K ++ S+P+WAI + +F +WS L+T P F VL ++ ENG +++L
Sbjct: 245 SSGRQSLPIKAMLKSLPLWAIILNSFAFIWSNSLLVTYTPTFISTVLHVNVRENGLLSSL 304
Query: 575 PYFLSAITFVLSGKLADIIRSRKWMSTTVTRKLFNTIGMLVNAIFIVAISFIGCDKVLVV 754
PY L+ I +L+G+++D +RK S RKLF T+G IFI+ + ++ + V
Sbjct: 305 PYLLAYICGILAGQMSDFFLTRKIFSIVTVRKLFTTLGSFCPVIFIMCLLYLSYNFYSTV 364
Query: 755 TFLCIA 772
FL +A
Sbjct: 365 IFLTLA 370
>sp|Q62795|NPT1_RAT Renal sodium-dependent phosphate transport protein 1
(Sodium/phosphate cotransporter 1) (Na(+)/PI
cotransporter 1) (Renal sodium-phosphate transport
protein 1) (Renal Na(+)-dependent phosphate
cotransporter 1) (Solute carrier family 18 member 1)
Length = 465
Score = 142 bits (357), Expect = 1e-33
Identities = 77/246 (31%), Positives = 125/246 (50%)
Frame = +2
Query: 35 RAGYGWLIALRVLEGAGESITYPAMHTMLGYWAPAMETTFIGGIVYSGSFXXXXXXXXXX 214
+ G +I RVL+G + H + WAP +E + + SG
Sbjct: 128 QVGAALVIVCRVLQGIAQGAVSTGQHGIWVKWAPPLERGRLTSMTLSGFVMGPFIALLVS 187
Query: 215 XXXXDANVMGGWPSVFYIPGIVGVLWFIIWSFVAYSTPAHHPRISEKEKRFIESSVNLSA 394
D + GWP VFYI GIVG + + W + + P +HP +S EK +I SS+
Sbjct: 188 GFICD---LLGWPMVFYIFGIVGCVLSLFWFILLFDDPNNHPYMSSSEKDYITSSLMQQV 244
Query: 395 EEKHTNVPWKQIMLSVPVWAISIANFCAMWSLYTLLTSLPQFFEYVLGFSISENGYINAL 574
++P K ++ S+P+WAI + +F +WS L+T P F L ++ ENG +++L
Sbjct: 245 HSGRQSLPIKAMLKSLPLWAIILNSFAFIWSNNLLVTYTPTFISTTLHVNVRENGLLSSL 304
Query: 575 PYFLSAITFVLSGKLADIIRSRKWMSTTVTRKLFNTIGMLVNAIFIVAISFIGCDKVLVV 754
PY L+ I +++G+++D + SRK S RKLF T+G+ IF+V + ++ + V
Sbjct: 305 PYLLAYICGIVAGQMSDFLLSRKIFSVVAVRKLFTTLGIFCPVIFVVCLLYLSYNFYSTV 364
Query: 755 TFLCIA 772
FL +A
Sbjct: 365 IFLTLA 370
>sp|Q14916|NPT1_HUMAN Renal sodium-dependent phosphate transport protein 1
(Sodium/phosphate cotransporter 1) (Na(+)/PI
cotransporter 1) (Renal sodium-phosphate transport
protein 1) (Renal Na(+)-dependent phosphate
cotransporter 1) (Solute carrier family 18 member 1)
(NA/PI-4)
Length = 465
Score = 139 bits (350), Expect = 9e-33
Identities = 80/246 (32%), Positives = 120/246 (48%)
Frame = +2
Query: 41 GYGWLIALRVLEGAGESITYPAMHTMLGYWAPAMETTFIGGIVYSGSFXXXXXXXXXXXX 220
G W++ R ++GA + I A + WAP +E + + SG
Sbjct: 130 GVAWVVVCRAVQGAAQGIVATAQFEIYVKWAPPLERGRLTSMSTSGFLLGPFIVLLVTGV 189
Query: 221 XXDANVMGGWPSVFYIPGIVGVLWFIIWSFVAYSTPAHHPRISEKEKRFIESSVNLSAEE 400
++ GWP VFYI G G ++W + Y P HP IS EK +I SS+
Sbjct: 190 ICESL---GWPMVFYIFGACGCAVCLLWFVLFYDDPKDHPCISISEKEYITSSLVQQVSS 246
Query: 401 KHTNVPWKQIMLSVPVWAISIANFCAMWSLYTLLTSLPQFFEYVLGFSISENGYINALPY 580
++P K I+ S+PVWAISI +F WS + P F +L +I ENG++++LPY
Sbjct: 247 SRQSLPIKAILKSLPVWAISIGSFTFFWSHNIMTLYTPMFINSMLHVNIKENGFLSSLPY 306
Query: 581 FLSAITFVLSGKLADIIRSRKWMSTTVTRKLFNTIGMLVNAIFIVAISFIGCDKVLVVTF 760
+ I L+G+L+D +R +S RKLF G L+ AIF V + ++ +V F
Sbjct: 307 LFAWICGNLAGQLSDFFLTRNILSVIAVRKLFTAAGFLLPAIFGVCLPYLSSTFYSIVIF 366
Query: 761 LCIAVA 778
L +A A
Sbjct: 367 LILAGA 372
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 91,278,878
Number of Sequences: 369166
Number of extensions: 1953401
Number of successful extensions: 5394
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 5133
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5347
length of database: 68,354,980
effective HSP length: 108
effective length of database: 48,403,600
effective search space used: 7308943600
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)