Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_015_G11
(614 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P54611|VATE_DROME Vacuolar ATP synthase subunit E (V-ATP... 162 8e-40
sp|P31402|VATE_MANSE Vacuolar ATP synthase subunit E (V-ATP... 152 7e-37
sp|P36543|VATE_HUMAN Vacuolar ATP synthase subunit E (V-ATP... 143 3e-34
sp|P11019|VATE_BOVIN Vacuolar ATP synthase subunit E (V-ATP... 142 9e-34
sp|Q9U1G5|VATE_HETSC Vacuolar ATP synthase subunit E (V-ATP... 135 8e-32
sp|P50518|VATE_MOUSE Vacuolar ATP synthase subunit E (V-ATP... 133 3e-31
sp|O94072|VATE_CANAL Vacuolar ATP synthase subunit E (V-ATP... 109 6e-24
sp|Q01278|VATE_NEUCR Vacuolar ATP synthase subunit E (V-ATP... 106 4e-23
sp|O00780|VATE_DICDI Vacuolar ATP synthase subunit E (V-ATP... 100 4e-21
sp|P22203|VATE_YEAST Vacuolar ATP synthase subunit E (V-ATP... 93 6e-19
>sp|P54611|VATE_DROME Vacuolar ATP synthase subunit E (V-ATPase E subunit) (Vacuolar
proton pump E subunit) (V-ATPase 28 kDa subunit)
Length = 226
Score = 162 bits (409), Expect = 8e-40
Identities = 82/156 (52%), Positives = 108/156 (69%)
Frame = +3
Query: 3 QHSNMMNQARLKILGCQQEHVKDVLTEAQKRLHNLTNDPQKYKETLKRLITQGLFQLLEA 182
Q SNM+NQARLK+L +++HV VL +A+KRL +T + +Y+ L +LI QGLFQ++E
Sbjct: 71 QSSNMLNQARLKVLKVREDHVSSVLDDARKRLGEVTKNQSEYETVLTKLIVQGLFQIMEP 130
Query: 183 KVIIRCCRGDIRLVEVILDECASAYEAKTEMKVELTINKDNCLPDDLAGGVELCVPNGRV 362
KVI+RC D+ LV +L Y+A+ VEL I++ + L D GGVEL NGR+
Sbjct: 131 KVILRCREVDVPLVRNVLPAAVEQYKAQINQNVELFIDEKDFLSADTCGGVELLALNGRI 190
Query: 363 KIVNTLESRLDLISQQLIPEIREILFGKNTNRIFND 470
K+ NTLESRLDLISQQL+PEIR LFG+N NR F D
Sbjct: 191 KVPNTLESRLDLISQQLVPEIRNALFGRNVNRKFTD 226
>sp|P31402|VATE_MANSE Vacuolar ATP synthase subunit E (V-ATPase E subunit) (Vacuolar
proton pump E subunit) (V-ATPase 28 kDa subunit)
Length = 226
Score = 152 bits (384), Expect = 7e-37
Identities = 80/156 (51%), Positives = 105/156 (67%)
Frame = +3
Query: 3 QHSNMMNQARLKILGCQQEHVKDVLTEAQKRLHNLTNDPQKYKETLKRLITQGLFQLLEA 182
Q SNM+NQARLK+L +++HV++VL EA+KRL + D + Y + L LI Q LFQL+E
Sbjct: 71 QSSNMLNQARLKVLKVREDHVRNVLDEARKRLAEVPKDIKLYSDLLVTLIVQALFQLVEP 130
Query: 183 KVIIRCCRGDIRLVEVILDECASAYEAKTEMKVELTINKDNCLPDDLAGGVELCVPNGRV 362
V +R + D LVE +L Y+AK + V L I+ +N LP D GG+EL GR+
Sbjct: 131 TVTLRVRQADKALVESLLGRAQQDYKAKIKKDVVLKIDNENFLPPDTCGGIELIAAKGRI 190
Query: 363 KIVNTLESRLDLISQQLIPEIREILFGKNTNRIFND 470
KI NTLESRL+LI+QQL+PEIR LFG+N NR F D
Sbjct: 191 KISNTLESRLELIAQQLLPEIRNALFGRNPNRKFTD 226
>sp|P36543|VATE_HUMAN Vacuolar ATP synthase subunit E (V-ATPase E subunit) (Vacuolar
proton pump E subunit) (V-ATPase 31 kDa subunit) (P31)
Length = 226
Score = 143 bits (361), Expect = 3e-34
Identities = 70/156 (44%), Positives = 109/156 (69%)
Frame = +3
Query: 3 QHSNMMNQARLKILGCQQEHVKDVLTEAQKRLHNLTNDPQKYKETLKRLITQGLFQLLEA 182
Q SN+MNQARLK+L + + + D+L EA++RL + D +Y+ L L+ QGL+QLLE
Sbjct: 71 QMSNLMNQARLKVLRARDDLITDLLNEAKQRLSKVVKDTTRYQVLLDGLVLQGLYQLLEP 130
Query: 183 KVIIRCCRGDIRLVEVILDECASAYEAKTEMKVELTINKDNCLPDDLAGGVELCVPNGRV 362
++I+RC + D LV+ + + Y+ T+ V++ I++++ LP+D+AGGVE+ + ++
Sbjct: 131 RMIVRCRKQDFPLVKAAVQKAIPMYKIATKNDVDVQIDQESYLPEDIAGGVEIYNGDRKI 190
Query: 363 KIVNTLESRLDLISQQLIPEIREILFGKNTNRIFND 470
K+ NTLESRLDLI+QQ++PE+R LFG N NR F D
Sbjct: 191 KVSNTLESRLDLIAQQMMPEVRGALFGANANRKFLD 226
>sp|P11019|VATE_BOVIN Vacuolar ATP synthase subunit E (V-ATPase E subunit) (Vacuolar
proton pump E subunit) (V-ATPase 31 kDa subunit) (P31)
Length = 226
Score = 142 bits (357), Expect = 9e-34
Identities = 69/156 (44%), Positives = 108/156 (69%)
Frame = +3
Query: 3 QHSNMMNQARLKILGCQQEHVKDVLTEAQKRLHNLTNDPQKYKETLKRLITQGLFQLLEA 182
Q SN+MNQARLK+L + + + D+L EA++RL + D +Y+ L L+ QGL+QLLE
Sbjct: 71 QMSNLMNQARLKVLRARDDLITDLLNEAKQRLSKVVKDTTRYQVLLDGLVLQGLYQLLEP 130
Query: 183 KVIIRCCRGDIRLVEVILDECASAYEAKTEMKVELTINKDNCLPDDLAGGVELCVPNGRV 362
++I+RC + D LV+ + + Y+ T+ V++ I+++ LP+++AGGVE+ + ++
Sbjct: 131 RMIVRCRKQDFPLVKAAVQKAIPVYKVATKRDVDVQIDQEAYLPEEIAGGVEIYNGDRKI 190
Query: 363 KIVNTLESRLDLISQQLIPEIREILFGKNTNRIFND 470
K+ NTLESRLDLI+QQ++PE+R LFG N NR F D
Sbjct: 191 KVSNTLESRLDLIAQQMMPEVRGALFGANANRKFLD 226
>sp|Q9U1G5|VATE_HETSC Vacuolar ATP synthase subunit E (V-ATPase E subunit) (Vacuolar
proton pump E subunit)
Length = 226
Score = 135 bits (340), Expect = 8e-32
Identities = 68/156 (43%), Positives = 103/156 (66%)
Frame = +3
Query: 3 QHSNMMNQARLKILGCQQEHVKDVLTEAQKRLHNLTNDPQKYKETLKRLITQGLFQLLEA 182
Q SNM NQ+RLK L + +H+K+VL EA+ L ++ D ++Y LK L+ QGLFQLLE+
Sbjct: 71 QRSNMQNQSRLKCLKARDDHLKNVLEEARANLSKISADRERYPAILKGLLLQGLFQLLES 130
Query: 183 KVIIRCCRGDIRLVEVILDECASAYEAKTEMKVELTINKDNCLPDDLAGGVELCVPNGRV 362
KV++RC + D +V IL EC + + E+ I+ ++ L + AGGVEL +G++
Sbjct: 131 KVVLRCRKKDEEMVARILPECLEEVQRTWGNRSEVKIDNEHFLSPESAGGVELLAKDGKI 190
Query: 363 KIVNTLESRLDLISQQLIPEIREILFGKNTNRIFND 470
++ +TLE+RLDLI+ ++ P++R LFG N NR F D
Sbjct: 191 RVSSTLEARLDLIADKITPQVRTALFGPNQNRRFFD 226
>sp|P50518|VATE_MOUSE Vacuolar ATP synthase subunit E (V-ATPase E subunit) (Vacuolar
proton pump E subunit) (V-ATPase 31 kDa subunit) (P31)
Length = 228
Score = 133 bits (335), Expect = 3e-31
Identities = 67/156 (42%), Positives = 105/156 (67%)
Frame = +3
Query: 3 QHSNMMNQARLKILGCQQEHVKDVLTEAQKRLHNLTNDPQKYKETLKRLITQGLFQLLEA 182
Q SN+MNQARLK+L + + + D+L EA++RL + D +Y+ L L+ QGL+QLLE
Sbjct: 73 QMSNLMNQARLKVLRARDDLITDLLNEAKQRLMKVVKDTTRYQVLLDGLVLQGLYQLLEP 132
Query: 183 KVIIRCCRGDIRLVEVILDECASAYEAKTEMKVELTINKDNCLPDDLAGGVELCVPNGRV 362
++I+RC + D LV+ + + Y+ T+ V++ I+++ ++AGGVE+ + ++
Sbjct: 133 RMIVRCRKQDFPLVKAAVQKAIPMYKIATKRDVDVQIDQEPTCLRNIAGGVEIYNGDRKI 192
Query: 363 KIVNTLESRLDLISQQLIPEIREILFGKNTNRIFND 470
K+ NTLESRLDLI+QQ++PE+R LFG N NR F D
Sbjct: 193 KVSNTLESRLDLIAQQMMPEVRGALFGANANRKFLD 228
>sp|O94072|VATE_CANAL Vacuolar ATP synthase subunit E (V-ATPase E subunit) (Vacuolar
proton pump E subunit)
Length = 226
Score = 109 bits (272), Expect = 6e-24
Identities = 56/154 (36%), Positives = 94/154 (61%)
Frame = +3
Query: 9 SNMMNQARLKILGCQQEHVKDVLTEAQKRLHNLTNDPQKYKETLKRLITQGLFQLLEAKV 188
S + N+ RL+IL + E + ++ EA+ L +T D ++YK L LI +G+ L+E KV
Sbjct: 73 STIGNKTRLRILSTKDEVLHEIFDEAEAELKKITKDKKQYKPVLVGLIEEGVLALMEPKV 132
Query: 189 IIRCCRGDIRLVEVILDECASAYEAKTEMKVELTINKDNCLPDDLAGGVELCVPNGRVKI 368
I+ D+ + + + E A +E K + KVE++I+ N L D+AGG+ + +G++++
Sbjct: 133 SIKVREQDVDVAKEAITEAAKNFEEKAKFKVEISIDDKNFLAKDIAGGIVVVNGSGKIEV 192
Query: 369 VNTLESRLDLISQQLIPEIREILFGKNTNRIFND 470
NTLE RL ++S++ +P IR LFG +T R F D
Sbjct: 193 DNTLEERLKILSEEALPAIRLELFGPSTTRKFFD 226
>sp|Q01278|VATE_NEUCR Vacuolar ATP synthase subunit E (V-ATPase E subunit) (Vacuolar
proton pump E subunit) (V-ATPase 26 kDa subunit)
Length = 230
Score = 106 bits (265), Expect = 4e-23
Identities = 54/154 (35%), Positives = 92/154 (59%)
Frame = +3
Query: 9 SNMMNQARLKILGCQQEHVKDVLTEAQKRLHNLTNDPQKYKETLKRLITQGLFQLLEAKV 188
S M N+ RL++LG +QE + ++ A +L T+D +YK+ L+ LI +G + + E ++
Sbjct: 77 STMANKTRLRVLGARQELLDEIFEAASAQLGQATHDLGRYKDILRDLILEGFYAMNEPEL 136
Query: 189 IIRCCRGDIRLVEVILDECASAYEAKTEMKVELTINKDNCLPDDLAGGVELCVPNGRVKI 368
+IR + D V ++ Y+ KT+ V+ TI+ +N +P+ AGG+ + NG++ I
Sbjct: 137 VIRARQADYDAVREAAGWASAQYKHKTDKDVKATIDAENPVPEGSAGGIIIVGGNGKIDI 196
Query: 369 VNTLESRLDLISQQLIPEIREILFGKNTNRIFND 470
NT E+RL L+ +P +R+ LFG+N NR F D
Sbjct: 197 DNTFEARLTLLKDSALPAMRKALFGENPNRKFFD 230
>sp|O00780|VATE_DICDI Vacuolar ATP synthase subunit E (V-ATPase E subunit) (Vacuolar
proton pump E subunit)
Length = 233
Score = 100 bits (248), Expect = 4e-21
Identities = 58/163 (35%), Positives = 93/163 (57%), Gaps = 9/163 (5%)
Frame = +3
Query: 9 SNMMNQARLKILGCQQEHVKDVLTEAQKRLHNLTNDPQKYKETLKRLITQGLFQLLEAKV 188
SN +N++RL +L ++E ++DV+ EAQK+L +++D KY+ LK LI QG +L E K+
Sbjct: 71 SNELNKSRLSVLKVREECLRDVIKEAQKKLATISDDKDKYQTILKNLIYQGFVKLNENKI 130
Query: 189 IIRCCRGDIRLVEVILDECASAYEAKTEMKVELTINKDNCLPD---------DLAGGVEL 341
+ + D L+E E A+ Y+ ++++++K+ LP GGV L
Sbjct: 131 QVVGRKEDAGLLEKATTEAAAQYKKNVGKSIDVSVDKERFLPQGPKSDYNGPTCCGGVIL 190
Query: 342 CVPNGRVKIVNTLESRLDLISQQLIPEIREILFGKNTNRIFND 470
GR+ NTL+SRL++ QL P IR L+G +T+R F D
Sbjct: 191 SALEGRIICKNTLDSRLEICFDQLTPVIRTQLYGASTSRKFFD 233
>sp|P22203|VATE_YEAST Vacuolar ATP synthase subunit E (V-ATPase E subunit) (Vacuolar
proton pump E subunit) (V-ATPase 27 kDa subunit)
Length = 233
Score = 92.8 bits (229), Expect = 6e-19
Identities = 50/156 (32%), Positives = 89/156 (57%), Gaps = 2/156 (1%)
Frame = +3
Query: 9 SNMMNQARLKILGCQQEHVKDVLTEAQKRLHNLTNDPQKYKETLKRLITQGLFQLLEAKV 188
S + N+ RLK+L +++ + + E +++L + N+ +YK L+ LI + L +LLE K
Sbjct: 78 STIANKMRLKVLSAREQSLDGIFEETKEKLSGIANNRDEYKPILQSLIVEALLKLLEPKA 137
Query: 189 IIRCCRGDIRLVEVILDECASAYEAKTEMK--VELTINKDNCLPDDLAGGVELCVPNGRV 362
I++ D+ L+E + D+ Y K + E+ I+ D D ++GGV + + ++
Sbjct: 138 IVKALERDVDLIESMKDDIMREYGEKAQRAPLEEIVISNDYLNKDLVSGGVVVSNASDKI 197
Query: 363 KIVNTLESRLDLISQQLIPEIREILFGKNTNRIFND 470
+I NTLE RL L+S++ +P IR L+G + R F D
Sbjct: 198 EINNTLEERLKLLSEEALPAIRLELYGPSKTRKFFD 233
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 69,582,221
Number of Sequences: 369166
Number of extensions: 1371338
Number of successful extensions: 3791
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3675
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3782
length of database: 68,354,980
effective HSP length: 105
effective length of database: 48,957,805
effective search space used: 4846822695
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)