Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_015_F13
(651 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P16219|ACADS_HUMAN Acyl-CoA dehydrogenase, short-chain s... 281 1e-75
sp|P15651|ACADS_RAT Acyl-CoA dehydrogenase, short-chain spe... 281 1e-75
sp|Q07417|ACADS_MOUSE Acyl-CoA dehydrogenase, short-chain s... 279 4e-75
sp|P79273|ACADS_PIG Acyl-CoA dehydrogenase, short-chain spe... 278 1e-74
sp|P45867|ACDA_BACSU Acyl-CoA dehydrogenase 191 1e-48
sp|P52042|ACDS_CLOAB Acyl-CoA dehydrogenase, short-chain sp... 176 6e-44
sp|Q06319|ACDS_MEGEL Acyl-CoA dehydrogenase, short-chain sp... 165 1e-40
sp|P45857|ACDB_BACSU Acyl-CoA dehydrogenase 163 4e-40
sp|P12007|IVD_RAT Isovaleryl-CoA dehydrogenase, mitochondri... 154 2e-37
sp|P26440|IVD_HUMAN Isovaleryl-CoA dehydrogenase, mitochond... 153 3e-37
>sp|P16219|ACADS_HUMAN Acyl-CoA dehydrogenase, short-chain specific, mitochondrial
precursor (SCAD) (Butyryl-CoA dehydrogenase)
Length = 412
Score = 281 bits (719), Expect = 1e-75
Identities = 138/221 (62%), Positives = 171/221 (77%), Gaps = 5/221 (2%)
Frame = +3
Query: 3 DYLAYTIAMEEISRGCASVGVVMTAHNSLYLAPLLKYGNVEQWKQFGTPFLTSGKIGCFA 182
DYLAY IAMEEISRGCAS GV+M+ +NSLYL P+LK+G+ EQ + + TPF + KIGCFA
Sbjct: 94 DYLAYAIAMEEISRGCASTGVIMSVNNSLYLGPILKFGSKEQKQAWVTPFTSGDKIGCFA 153
Query: 183 LSEPANGSDAGAASTTARKDGDNWILNGTKSWITNGYESEAAIVFATTDKSLKHKGISAF 362
LSEP NGSDAGAASTTAR +GD+W+LNGTK+WITN +E+ AA+VFA+TD++L++KGISAF
Sbjct: 154 LSEPGNGSDAGAASTTARAEGDSWVLNGTKAWITNAWEASAAVVFASTDRALQNKGISAF 213
Query: 363 IVPKPTPGLSLGKKEDKLGIRASSTCQLIFEDCKIPSSNILGQPGFGFKIAMKTLDGGRX 542
+VP PTPGL+LGKKEDKLGIR SST LIFEDC+IP +ILG+PG GFKIAM+TLD GR
Sbjct: 214 LVPMPTPGLTLGKKEDKLGIRGSSTANLIFEDCRIPKDSILGEPGMGFKIAMQTLDMGRI 273
Query: 543 XXXXXXXXXXXXXXECAVDYSTRGNLFLS-----QLLNFKL 650
+CAV+Y+ F + Q++ FKL
Sbjct: 274 GIASQALGIAQTALDCAVNYAENRMAFGAPLTKLQVIQFKL 314
>sp|P15651|ACADS_RAT Acyl-CoA dehydrogenase, short-chain specific, mitochondrial
precursor (SCAD) (Butyryl-CoA dehydrogenase)
Length = 412
Score = 281 bits (719), Expect = 1e-75
Identities = 139/221 (62%), Positives = 173/221 (78%), Gaps = 5/221 (2%)
Frame = +3
Query: 3 DYLAYTIAMEEISRGCASVGVVMTAHNSLYLAPLLKYGNVEQWKQFGTPFLTSGKIGCFA 182
DYLAY+IA+EEISRGCAS GV+M+ +NSLYL P+LK+G+ +Q +Q+ TPF KIGCFA
Sbjct: 94 DYLAYSIALEEISRGCASTGVIMSVNNSLYLGPILKFGSSQQKQQWITPFTNGDKIGCFA 153
Query: 183 LSEPANGSDAGAASTTARKDGDNWILNGTKSWITNGYESEAAIVFATTDKSLKHKGISAF 362
LSEP NGSDAGAASTTAR++GD+W+LNGTK+WITN +E+ A +VFA+TD+S ++KGISAF
Sbjct: 154 LSEPGNGSDAGAASTTAREEGDSWVLNGTKAWITNSWEASATVVFASTDRSRQNKGISAF 213
Query: 363 IVPKPTPGLSLGKKEDKLGIRASSTCQLIFEDCKIPSSNILGQPGFGFKIAMKTLDGGRX 542
+VP PTPGL+LGKKEDKLGIRASST LIFEDC+IP N+LG+PG GFKIAM+TLD GR
Sbjct: 214 LVPMPTPGLTLGKKEDKLGIRASSTANLIFEDCRIPKENLLGEPGMGFKIAMQTLDMGRI 273
Query: 543 XXXXXXXXXXXXXXECAVDYSTRGNLF---LSQLLN--FKL 650
+CAV Y+ + F L++L N FKL
Sbjct: 274 GIASQALGIAQASLDCAVKYAENRHAFGAPLTKLQNIQFKL 314
>sp|Q07417|ACADS_MOUSE Acyl-CoA dehydrogenase, short-chain specific, mitochondrial
precursor (SCAD) (Butyryl-CoA dehydrogenase)
Length = 412
Score = 279 bits (714), Expect = 4e-75
Identities = 138/220 (62%), Positives = 171/220 (77%), Gaps = 5/220 (2%)
Frame = +3
Query: 6 YLAYTIAMEEISRGCASVGVVMTAHNSLYLAPLLKYGNVEQWKQFGTPFLTSGKIGCFAL 185
YLAY+IA+EEISR CAS GV+M+ +NSLYL P+LK+G+ +Q +Q+ TPF KIGCFAL
Sbjct: 95 YLAYSIALEEISRACASTGVIMSVNNSLYLGPILKFGSAQQKQQWITPFTNGDKIGCFAL 154
Query: 186 SEPANGSDAGAASTTARKDGDNWILNGTKSWITNGYESEAAIVFATTDKSLKHKGISAFI 365
SEP NGSDAGAASTTAR++GD+W+LNGTK+WITN +E+ A +VFA+TD+S ++KGISAF+
Sbjct: 155 SEPGNGSDAGAASTTAREEGDSWVLNGTKAWITNSWEASATVVFASTDRSRQNKGISAFL 214
Query: 366 VPKPTPGLSLGKKEDKLGIRASSTCQLIFEDCKIPSSNILGQPGFGFKIAMKTLDGGRXX 545
VP PTPGL+LGKKEDKLGIRASST LIFEDC+IP N+LG+PG GFKIAM+TLD GR
Sbjct: 215 VPMPTPGLTLGKKEDKLGIRASSTANLIFEDCRIPKENLLGEPGMGFKIAMQTLDMGRIG 274
Query: 546 XXXXXXXXXXXXXECAVDYSTRGNLF---LSQLLN--FKL 650
+CAV Y+ N F L++L N FKL
Sbjct: 275 IASQALGIAQASLDCAVKYAENRNAFGAPLTKLQNIQFKL 314
>sp|P79273|ACADS_PIG Acyl-CoA dehydrogenase, short-chain specific, mitochondrial
precursor (SCAD) (Butyryl-CoA dehydrogenase)
Length = 413
Score = 278 bits (710), Expect = 1e-74
Identities = 133/207 (64%), Positives = 164/207 (79%)
Frame = +3
Query: 3 DYLAYTIAMEEISRGCASVGVVMTAHNSLYLAPLLKYGNVEQWKQFGTPFLTSGKIGCFA 182
DYLAYTIAMEEISRGCAS GV+M+ +N LYL P+LK+G+ EQ +Q+ TPF + K+GCFA
Sbjct: 94 DYLAYTIAMEEISRGCASTGVIMSVNNFLYLGPILKFGSKEQKQQWITPFTSGDKVGCFA 153
Query: 183 LSEPANGSDAGAASTTARKDGDNWILNGTKSWITNGYESEAAIVFATTDKSLKHKGISAF 362
LSEP NGSDAGAA+TTA+ D D+W+L+GTK+WITN +E+ AA+VFA+TD+SL++KGISAF
Sbjct: 154 LSEPGNGSDAGAAATTAQADHDSWVLSGTKAWITNAWEASAAVVFASTDRSLQNKGISAF 213
Query: 363 IVPKPTPGLSLGKKEDKLGIRASSTCQLIFEDCKIPSSNILGQPGFGFKIAMKTLDGGRX 542
+VP PT GL+LGKKEDKLGIRASST LIFEDC+IP N+LG+PG GFKIAMKTLD GR
Sbjct: 214 LVPMPTAGLTLGKKEDKLGIRASSTANLIFEDCRIPKENLLGEPGMGFKIAMKTLDMGRI 273
Query: 543 XXXXXXXXXXXXXXECAVDYSTRGNLF 623
+CAV+Y+ F
Sbjct: 274 GIASKALGISQAALDCAVNYAENRRAF 300
>sp|P45867|ACDA_BACSU Acyl-CoA dehydrogenase
Length = 379
Score = 191 bits (486), Expect = 1e-48
Identities = 101/207 (48%), Positives = 132/207 (63%)
Frame = +3
Query: 3 DYLAYTIAMEEISRGCASVGVVMTAHNSLYLAPLLKYGNVEQWKQFGTPFLTSGKIGCFA 182
DYLAY IA+EE+S+ CAS GV ++AH SL PL +G EQ ++ T KIG FA
Sbjct: 65 DYLAYVIAVEELSKVCASTGVTLSAHISLCSWPLFAFGTEEQKTEYLTQLALGEKIGAFA 124
Query: 183 LSEPANGSDAGAASTTARKDGDNWILNGTKSWITNGYESEAAIVFATTDKSLKHKGISAF 362
L+E +GSDAG+ TTA + GD+++LNG+K +ITNG ++ IVFA TD K KG++AF
Sbjct: 125 LTEAGSGSDAGSMKTTAERIGDDYVLNGSKVFITNGGVADIYIVFAVTDPEKKKKGVTAF 184
Query: 363 IVPKPTPGLSLGKKEDKLGIRASSTCQLIFEDCKIPSSNILGQPGFGFKIAMKTLDGGRX 542
IV K G GKKE KLGIR+S T +++FEDC +P+S LG+ G GFKIAMKTLDGGR
Sbjct: 185 IVEKDFEGFFTGKKEKKLGIRSSPTTEIMFEDCVVPASKRLGEEGEGFKIAMKTLDGGRN 244
Query: 543 XXXXXXXXXXXXXXECAVDYSTRGNLF 623
+ A+ Y+ F
Sbjct: 245 GIAAQAVGIAQGALDAALQYAKERKQF 271
>sp|P52042|ACDS_CLOAB Acyl-CoA dehydrogenase, short-chain specific (SCAD) (Butyryl-CoA
dehydrogenase)
Length = 379
Score = 176 bits (445), Expect = 6e-44
Identities = 86/179 (48%), Positives = 126/179 (70%)
Frame = +3
Query: 3 DYLAYTIAMEEISRGCASVGVVMTAHNSLYLAPLLKYGNVEQWKQFGTPFLTSGKIGCFA 182
D L+Y IA+EE+S+ C + GV+++AH SL + + ++G EQ +++ P KIG +
Sbjct: 65 DVLSYIIAVEELSKVCGTTGVILSAHTSLCASLINEHGTEEQKQKYLVPLAKGEKIGAYG 124
Query: 183 LSEPANGSDAGAASTTARKDGDNWILNGTKSWITNGYESEAAIVFATTDKSLKHKGISAF 362
L+EP G+D+GA T A +GD++++NG+K +ITNG ++ ++FA TD++ KGISAF
Sbjct: 125 LTEPNAGTDSGAQQTVAVLEGDHYVINGSKIFITNGGVADTFVIFAMTDRTKGTKGISAF 184
Query: 363 IVPKPTPGLSLGKKEDKLGIRASSTCQLIFEDCKIPSSNILGQPGFGFKIAMKTLDGGR 539
I+ K G S+GK E KLGIRASST +L+FED +P N++G+ G GF IAMKTLDGGR
Sbjct: 185 IIEKGFKGFSIGKVEQKLGIRASSTTELVFEDMIVPVENMIGKEGKGFPIAMKTLDGGR 243
>sp|Q06319|ACDS_MEGEL Acyl-CoA dehydrogenase, short-chain specific (SCAD) (Butyryl-CoA
dehydrogenase) (BCAD)
Length = 383
Score = 165 bits (417), Expect = 1e-40
Identities = 91/216 (42%), Positives = 130/216 (60%), Gaps = 1/216 (0%)
Frame = +3
Query: 3 DYLAYTIAMEEISRGCASVGVVMTAHNSLYLAPLLKYGNVEQWKQFGTPFLTSGKIGCFA 182
D L+Y +A+EE+++ A V + ++A SL P+ ++G Q ++F P + K+G F
Sbjct: 68 DVLSYILAVEELAKYDAGVAITLSATVSLCANPIWQFGTEAQKEKFLVPLVEGTKLGAFG 127
Query: 183 LSEPANGSDAGAASTTARKDGDN-WILNGTKSWITNGYESEAAIVFATTDKSLKHKGISA 359
L+EP G+DA T A K+ D + LNG+K +ITNG ++ IVFA TDKS + GI+A
Sbjct: 128 LTEPNAGTDASGQQTIATKNDDGTYTLNGSKIFITNGGAADIYIVFAMTDKSKGNHGITA 187
Query: 360 FIVPKPTPGLSLGKKEDKLGIRASSTCQLIFEDCKIPSSNILGQPGFGFKIAMKTLDGGR 539
FI+ TPG + GKKEDK+GI S T +L+F+D K+P+ N+LG+ G GFKIAM TLDGGR
Sbjct: 188 FILEDGTPGFTYGKKEDKMGIHTSQTMELVFQDVKVPAENMLGEEGKGFKIAMMTLDGGR 247
Query: 540 XXXXXXXXXXXXXXXECAVDYSTRGNLFLSQLLNFK 647
AV+YS + F L F+
Sbjct: 248 IGVAAQALGIAEAALADAVEYSKQRVQFGKPLCKFQ 283
>sp|P45857|ACDB_BACSU Acyl-CoA dehydrogenase
Length = 378
Score = 163 bits (412), Expect = 4e-40
Identities = 96/222 (43%), Positives = 137/222 (61%), Gaps = 6/222 (2%)
Frame = +3
Query: 3 DYLAYTIAMEEISRGCASVGVVMTAHNSLYLAPLLKYGNVEQWKQFGTPFLTSGK-IGCF 179
D ++Y +A+ EISR A+VGV+++ H S+ P+L +GN EQ ++ P L SG +G F
Sbjct: 63 DVVSYILAIHEISRISAAVGVILSVHTSVGTNPILYFGNEEQKMKY-IPNLASGDHLGAF 121
Query: 180 ALSEPANGSDAGAASTTARKDGDNWILNGTKSWITNGYESEAAIVFATTDKSLKHKGISA 359
AL+EP +GSDAG+ TTA K ++LNG+K +ITNG ++ I FA T GISA
Sbjct: 122 ALTEPHSGSDAGSLRTTAIKKNGKYLLNGSKIFITNGGAADIYITFALTAPDQGRHGISA 181
Query: 360 FIVPKPTPGLSLGKKEDKLGIRASSTCQLIFEDCKIPSSNILGQPGFGFKIAMKTLDGGR 539
FIV K TPG ++GKKE KLG+ S+T +LIF++ ++P +N+LG+ G GF IAM L+ GR
Sbjct: 182 FIVEKNTPGFTVGKKERKLGLYGSNTTELIFDNAEVPEANLLGKEGDGFHIAMANLNVGR 241
Query: 540 XXXXXXXXXXXXXXXECAVDYSTRGNLF-----LSQLLNFKL 650
E AVDY+ + F +Q ++FKL
Sbjct: 242 IGIAAQALGIAEAALEHAVDYAKQRVQFGRPIAANQGISFKL 283
>sp|P12007|IVD_RAT Isovaleryl-CoA dehydrogenase, mitochondrial precursor (IVD)
Length = 424
Score = 154 bits (389), Expect = 2e-37
Identities = 82/178 (46%), Positives = 117/178 (65%), Gaps = 3/178 (1%)
Frame = +3
Query: 6 YLAYTIAMEEISRGCASVGVVMTAHNSLYLAPLLKYGNVEQWKQFGTPFLTSGK-IGCFA 182
YL + + MEEISR A+VG+ AH++L + +++ GN Q +++ P L SG+ IG A
Sbjct: 106 YLEHVLVMEEISRASAAVGLSYGAHSNLCINQIVRNGNEAQKEKY-LPKLISGEFIGALA 164
Query: 183 LSEPANGSDAGAASTTARKDGDNWILNGTKSWITNGYESEAAIVFATTDKSL--KHKGIS 356
+SEP GSD + A K GD+++LNG K WITNG +++ +V+A TD + +GI+
Sbjct: 165 MSEPNAGSDVVSMRLKAEKKGDHYVLNGNKFWITNGPDADVLVVYAKTDLTAVPASRGIT 224
Query: 357 AFIVPKPTPGLSLGKKEDKLGIRASSTCQLIFEDCKIPSSNILGQPGFGFKIAMKTLD 530
AFIV K PG S KK DKLG+R S+TC+L+FEDCK+P++NIL Q G + M LD
Sbjct: 225 AFIVEKDMPGFSTSKKLDKLGMRGSNTCELVFEDCKVPAANILSQESKGVYVLMSGLD 282
>sp|P26440|IVD_HUMAN Isovaleryl-CoA dehydrogenase, mitochondrial precursor (IVD)
Length = 423
Score = 153 bits (387), Expect = 3e-37
Identities = 81/177 (45%), Positives = 113/177 (63%), Gaps = 2/177 (1%)
Frame = +3
Query: 6 YLAYTIAMEEISRGCASVGVVMTAHNSLYLAPLLKYGNVEQWKQFGTPFLTSGKIGCFAL 185
YL + + MEEISR +VG+ AH++L + L++ GN Q +++ ++ IG A+
Sbjct: 105 YLEHVLVMEEISRASGAVGLSYGAHSNLCINQLVRNGNEAQKEKYLPKLISGEYIGALAM 164
Query: 186 SEPANGSDAGAASTTARKDGDNWILNGTKSWITNGYESEAAIVFATTDKSL--KHKGISA 359
SEP GSD + A K G+++ILNG K WITNG +++ IV+A TD + +GI+A
Sbjct: 165 SEPNAGSDVVSMKLKAEKKGNHYILNGNKFWITNGPDADVLIVYAKTDLAAVPASRGITA 224
Query: 360 FIVPKPTPGLSLGKKEDKLGIRASSTCQLIFEDCKIPSSNILGQPGFGFKIAMKTLD 530
FIV K PG S KK DKLG+R S+TC+LIFEDCKIP++NILG G + M LD
Sbjct: 225 FIVEKGMPGFSTSKKLDKLGMRGSNTCELIFEDCKIPAANILGHENKGVYVLMSGLD 281
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 75,522,156
Number of Sequences: 369166
Number of extensions: 1499815
Number of successful extensions: 3884
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3705
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3806
length of database: 68,354,980
effective HSP length: 106
effective length of database: 48,773,070
effective search space used: 5365037700
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)