Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_015_D21
(554 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P31226|SAX_RANCA Saxiphilin precursor (SAX) 61 2e-09
sp|P01267|THYG_BOVIN Thyroglobulin precursor 54 2e-07
sp|O08710|THYG_MOUSE Thyroglobulin precursor 53 4e-07
sp|P06882|THYG_RAT Thyroglobulin precursor 53 6e-07
sp|P01266|THYG_HUMAN Thyroglobulin precursor 51 2e-06
sp|P81439|EQST_ACTEQ Equistatin 48 1e-05
sp|O88322|NID2_MOUSE Nidogen-2 precursor (NID-2) (Entactin-2) 47 2e-05
sp|Q14112|NID2_HUMAN Nidogen-2 precursor (NID-2) (Osteonido... 47 3e-05
sp|Q8BKV0|TICN3_MOUSE Testican-3 precursor (SPARC/osteonect... 45 2e-04
sp|Q9BQ16|TICN3_HUMAN Testican-3 precursor (SPARC/osteonect... 44 2e-04
>sp|P31226|SAX_RANCA Saxiphilin precursor (SAX)
Length = 844
Score = 61.2 bits (147), Expect = 2e-09
Identities = 43/137 (31%), Positives = 62/137 (45%), Gaps = 11/137 (8%)
Frame = +3
Query: 72 NNDQCNVGLICDEVCKEDNNAPKCFKRHLDARRLIKSGAMDVTFPFCEDTGMYKPVQCVG 251
+ D N+ I E + + KC K A + + P C++ G Y+P QC G
Sbjct: 87 SKDPYNLKPIIAEPYSSNRDLQKCLKERQQA---LAKKMIGHYIPQCDEKGNYQPQQCHG 143
Query: 252 AA--CWCVDDSGDEIKGYITGIEKSYGKTCN------CAKDKHEY--SQRKIIGRFF-HC 398
+ CWCV+ G++I G T ++ TC C K++ K++GRF C
Sbjct: 144 STGHCWCVNAMGEKISGTNTPPGQTRA-TCERHELPKCLKERQVALGGDEKVLGRFVPQC 202
Query: 399 DHLGNYEKVQCHGSVCY 449
D GNYE Q HGS Y
Sbjct: 203 DEKGNYEPQQFHGSTGY 219
Score = 43.9 bits (102), Expect = 3e-04
Identities = 26/71 (36%), Positives = 37/71 (52%), Gaps = 9/71 (12%)
Frame = +3
Query: 339 CAKDKHEYSQRKIIGRFF-HCDHLGNYEKVQCHGSV--CYYADSSGKKI-----PTSPTV 494
C K++ + +K+IG + CD GNY+ QCHGS C+ ++ G+KI P T
Sbjct: 110 CLKERQQALAKKMIGHYIPQCDEKGNYQPQQCHGSTGHCWCVNAMGEKISGTNTPPGQTR 169
Query: 495 HIAERDSL-KC 524
ER L KC
Sbjct: 170 ATCERHELPKC 180
Score = 33.9 bits (76), Expect = 0.28
Identities = 22/64 (34%), Positives = 31/64 (48%), Gaps = 5/64 (7%)
Frame = +3
Query: 120 EDNNAPKCFKRHLDARRLIKSGAMDVT---FPFCEDTGMYKPVQCVGAA--CWCVDDSGD 284
E + PKC K R++ G V P C++ G Y+P Q G+ WCV+ G+
Sbjct: 173 ERHELPKCLKE----RQVALGGDEKVLGRFVPQCDEKGNYEPQQFHGSTGYSWCVNAIGE 228
Query: 285 EIKG 296
EI G
Sbjct: 229 EIAG 232
>sp|P01267|THYG_BOVIN Thyroglobulin precursor
Length = 2769
Score = 54.3 bits (129), Expect = 2e-07
Identities = 31/100 (31%), Positives = 41/100 (41%), Gaps = 8/100 (8%)
Frame = +3
Query: 204 PFCEDTGMYKPVQCVGAACWCVDDSGDEIKGYITGIEKSYGKTCNCAKDKHEYSQRKIIG 383
P C G Y+ VQC CWCVD G E+ G + C +K + ++G
Sbjct: 617 PACTAEGSYEEVQCFAGDCWCVDAQGRELAG---SRVRGGRPRCPTECEKQRARMQSLLG 673
Query: 384 R--------FFHCDHLGNYEKVQCHGSVCYYADSSGKKIP 479
C GN+ VQC S CY D+ G+ IP
Sbjct: 674 SQPAGSSLFVPACTSKGNFLPVQCFNSECYCVDTEGQPIP 713
Score = 46.2 bits (108), Expect = 5e-05
Identities = 28/104 (26%), Positives = 45/104 (43%), Gaps = 13/104 (12%)
Frame = +3
Query: 204 PFCEDTGMYKPVQCV--GAACWCVDDSGDEIKGYITGIEKSYGKTCNCAKDKHEYSQRKI 377
P C + G ++ VQC GA+CWCVD G E+ G + G+ C Q+ +
Sbjct: 50 PQCAEDGSFQTVQCGKDGASCWCVDADGREVPG-----SRQPGRPAACLSFCQLQKQQIL 104
Query: 378 IGRFFH---------CDHLGNYEKVQC--HGSVCYYADSSGKKI 476
+ + + C G+Y VQC C+ D+ G ++
Sbjct: 105 LSSYINSTATSYLPQCQDSGDYSPVQCDLRRRQCWCVDAEGMEV 148
Score = 42.7 bits (99), Expect = 6e-04
Identities = 22/58 (37%), Positives = 30/58 (51%), Gaps = 1/58 (1%)
Frame = +3
Query: 204 PFCEDTGMYKPVQCV-GAACWCVDDSGDEIKGYITGIEKSYGKTCNCAKDKHEYSQRK 374
P C G Y+ QC G CWCVD G EI G + G+ +CA+D+ S+R+
Sbjct: 317 PSCHPDGEYQAAQCQQGGPCWCVDSRGQEIPG-----TRQRGEPPSCAEDQSCPSERR 369
Score = 41.2 bits (95), Expect = 0.002
Identities = 26/82 (31%), Positives = 36/82 (43%), Gaps = 6/82 (7%)
Frame = +3
Query: 204 PFCEDTGMYKPVQCV--GAACWCVDDSGDEIKGYITGIEKSYGKTCNCAKDKHEYSQRKI 377
P C+D+G Y PVQC CWCVD G E+ G + G+ C + ++R +
Sbjct: 118 PQCQDSGDYSPVQCDLRRRQCWCVDAEGMEVYG-----TRQQGRPARCPRSCEIRNRRLL 172
Query: 378 IG----RFFHCDHLGNYEKVQC 431
G C G + VQC
Sbjct: 173 HGVGDRSPPQCSPDGAFRPVQC 194
Score = 38.5 bits (88), Expect = 0.011
Identities = 28/120 (23%), Positives = 42/120 (35%), Gaps = 20/120 (16%)
Frame = +3
Query: 138 KCFKRHLDARRLIKS--GAMDVTFPFCEDTGMYKPVQCVGAACWCVDDSGDEIKGYITGI 311
+C K+ + L+ S + P C G + PVQC + C+CVD G I G
Sbjct: 660 ECEKQRARMQSLLGSQPAGSSLFVPACTSKGNFLPVQCFNSECYCVDTEGQP----IPGT 715
Query: 312 EKSYGKTCNCAKDKHEYSQRKIIGR------------------FFHCDHLGNYEKVQCHG 437
+ G+ C ++R +G C G + VQC G
Sbjct: 716 RSALGEPKKCPSPCQLQAERAFLGTVRTLVSNPSTLPALSSIYIPQCSASGQWSPVQCDG 775
Score = 35.4 bits (80), Expect = 0.095
Identities = 15/34 (44%), Positives = 20/34 (58%), Gaps = 2/34 (5%)
Frame = +3
Query: 396 CDHLGNYEKVQCHGSV--CYYADSSGKKIPTSPT 491
CD G +E VQCH + C+ D G+ +PTS T
Sbjct: 1031 CDAFGGWEPVQCHAATGHCWCVDGKGEYVPTSLT 1064
Score = 35.0 bits (79), Expect = 0.12
Identities = 15/36 (41%), Positives = 21/36 (58%), Gaps = 2/36 (5%)
Frame = +3
Query: 204 PFCEDTGMYKPVQCVGAA--CWCVDDSGDEIKGYIT 305
P C+ G ++PVQC A CWCVD G+ + +T
Sbjct: 1029 PQCDAFGGWEPVQCHAATGHCWCVDGKGEYVPTSLT 1064
Score = 33.1 bits (74), Expect = 0.47
Identities = 16/34 (47%), Positives = 21/34 (61%), Gaps = 3/34 (8%)
Frame = +3
Query: 204 PFCE-DTGMYKPVQCVGA--ACWCVDDSGDEIKG 296
P C + G + PVQC A +CWCV SG+E+ G
Sbjct: 1167 PACRAEDGGFSPVQCDPAQGSCWCVLGSGEEVPG 1200
Score = 30.8 bits (68), Expect = 2.3
Identities = 28/105 (26%), Positives = 41/105 (39%), Gaps = 9/105 (8%)
Frame = +3
Query: 192 DVTFPFCEDTGMYKPVQCVGAACWCVDDSGDEIKGYITGIEKSYGKTCNCAK-----DKH 356
D+ P C +TG + +Q A WCVD + E G+ + C
Sbjct: 1102 DLFIPTCLETGEFARLQASEAGTWCVDPASGE------GVPPGTNSSAQCPSLCEVLQSG 1155
Query: 357 EYSQRKIIGRFFHC-DHLGNYEKVQC---HGSVCYYADSSGKKIP 479
S+R G C G + VQC GS C+ SG+++P
Sbjct: 1156 VPSRRTSPGYSPACRAEDGGFSPVQCDPAQGS-CWCVLGSGEEVP 1199
Score = 29.6 bits (65), Expect = 5.2
Identities = 11/30 (36%), Positives = 18/30 (60%)
Frame = +3
Query: 396 CDHLGNYEKVQCHGSVCYYADSSGKKIPTS 485
C G+YE+VQC C+ D+ G+++ S
Sbjct: 619 CTAEGSYEEVQCFAGDCWCVDAQGRELAGS 648
>sp|O08710|THYG_MOUSE Thyroglobulin precursor
Length = 2766
Score = 53.1 bits (126), Expect = 4e-07
Identities = 37/114 (32%), Positives = 49/114 (42%), Gaps = 7/114 (6%)
Frame = +3
Query: 204 PFCEDTGMYKPVQCVGAACWCVDDSGDEIKGYITGIEKSYGKTCNCAKDKHEY----SQR 371
P C G Y+ +QC CWCVD G E+ G + T C K + + S +
Sbjct: 618 PSCTAGGSYEDIQCYAGECWCVDSRGKELDGSRVRGGRPRCPT-KCEKQRAQMQSLASAQ 676
Query: 372 KIIGRFF--HCDHLGNYEKVQCHGSVCYYADSSGKKIP-TSPTVHIAERDSLKC 524
FF C G + VQC S CY D+ G+ IP T TV A++ C
Sbjct: 677 PAGSSFFVPTCTREGYFLPVQCFNSECYCVDTEGQVIPGTQSTVGEAKQCPSVC 730
Score = 52.0 bits (123), Expect = 1e-06
Identities = 30/104 (28%), Positives = 46/104 (44%), Gaps = 13/104 (12%)
Frame = +3
Query: 204 PFCEDTGMYKPVQCV--GAACWCVDDSGDEIKGYITGIEKSYGKTCNCAKDKHEYSQRKI 377
P C + G ++ VQC G +CWCVD G E+ G + G+ C + QR +
Sbjct: 51 PQCSEDGSFQTVQCQNDGQSCWCVDSDGREVPG-----SRQLGRPTVCLSFCQLHKQRIL 105
Query: 378 IGRFFH---------CDHLGNYEKVQC--HGSVCYYADSSGKKI 476
+G + + C GNY VQC C+ D+ G ++
Sbjct: 106 LGSYINSTDALYLPQCQDSGNYAPVQCDLQRVQCWCVDTEGMEV 149
Score = 41.6 bits (96), Expect = 0.001
Identities = 26/82 (31%), Positives = 36/82 (43%), Gaps = 6/82 (7%)
Frame = +3
Query: 204 PFCEDTGMYKPVQC--VGAACWCVDDSGDEIKGYITGIEKSYGKTCNCAKDKHEYSQRKI 377
P C+D+G Y PVQC CWCVD G E+ G + G+ C + ++R +
Sbjct: 119 PQCQDSGNYAPVQCDLQRVQCWCVDTEGMEVYG-----TRQQGRPTRCPRSCEIRNRRLL 173
Query: 378 IG----RFFHCDHLGNYEKVQC 431
G C G + VQC
Sbjct: 174 HGVGDRSPPQCTADGEFMPVQC 195
Score = 38.5 bits (88), Expect = 0.011
Identities = 21/65 (32%), Positives = 32/65 (49%), Gaps = 2/65 (3%)
Frame = +3
Query: 204 PFCEDTGMYKPVQC-VGAACWCVDDSGDEIKGYITGIEKSYGKTCNCAKDKH-EYSQRKI 377
P C G Y+ VQC CWCVD G E+ G + G+ +CA D+ +++
Sbjct: 318 PRCHRDGHYQTVQCQTEGMCWCVDAQGREVPG-----TRQQGQPPSCAADQSCALERQQA 372
Query: 378 IGRFF 392
+ RF+
Sbjct: 373 LSRFY 377
Score = 38.5 bits (88), Expect = 0.011
Identities = 32/108 (29%), Positives = 46/108 (42%), Gaps = 4/108 (3%)
Frame = +3
Query: 183 GAMDVTFPFCEDTGMYKPVQCVGAACWCVDDSGDEIKGYITGIEKSYGKTCNCAKDKHEY 362
G D+ P C TG Y Q G WCVD + E T C+ K +
Sbjct: 1100 GPGDLFIPVCLQTGEYVRKQTSGTGTWCVDPASGEGMPVNTNGSAQCPGLCDVLKSR-AL 1158
Query: 363 SQRKIIGRFFHCDHL-GNYEKVQC---HGSVCYYADSSGKKIPTSPTV 494
S++ +G C+ L G + VQC GS C+ SG+++P + V
Sbjct: 1159 SRKVGLGYSPVCEALDGAFSPVQCDLAQGS-CWCVLGSGEEVPGTRVV 1205
Score = 35.4 bits (80), Expect = 0.095
Identities = 18/55 (32%), Positives = 29/55 (52%), Gaps = 2/55 (3%)
Frame = +3
Query: 369 RKIIGRFF--HCDHLGNYEKVQCHGSVCYYADSSGKKIPTSPTVHIAERDSLKCD 527
+++ G+FF C G+YE +QC+ C+ DS GK++ S R KC+
Sbjct: 609 KQMPGKFFVPSCTAGGSYEDIQCYAGECWCVDSRGKELDGSRVRGGRPRCPTKCE 663
Score = 33.5 bits (75), Expect = 0.36
Identities = 15/33 (45%), Positives = 18/33 (54%), Gaps = 2/33 (6%)
Frame = +3
Query: 204 PFCEDTGMYKPVQCVGAA--CWCVDDSGDEIKG 296
P C G ++PVQC CWCVD G+ I G
Sbjct: 1030 PQCNMIGGWEPVQCHAGTGQCWCVDGRGEFIPG 1062
>sp|P06882|THYG_RAT Thyroglobulin precursor
Length = 2768
Score = 52.8 bits (125), Expect = 6e-07
Identities = 30/100 (30%), Positives = 45/100 (45%), Gaps = 8/100 (8%)
Frame = +3
Query: 204 PFCEDTGMYKPVQCVGAACWCVDDSGDEIKGYITGIEKSYGKTCNCAKDKHEYSQRKIIG 383
P C G Y+ +QC CWCV+ G E++G + + + + C +K + + G
Sbjct: 618 PSCTAEGSYEDIQCYAGECWCVNSQGKEVEG--SRVSGGHPR-CPTKCEKQRAQMQNLAG 674
Query: 384 ------RFF--HCDHLGNYEKVQCHGSVCYYADSSGKKIP 479
FF C G + VQC S CY D+ G+ IP
Sbjct: 675 AQPAGSSFFVPTCTSEGYFLPVQCFNSECYCVDAEGQVIP 714
Score = 50.8 bits (120), Expect = 2e-06
Identities = 30/108 (27%), Positives = 46/108 (42%), Gaps = 13/108 (12%)
Frame = +3
Query: 192 DVTFPFCEDTGMYKPVQCV--GAACWCVDDSGDEIKGYITGIEKSYGKTCNCAKDKHEYS 365
D P C + G ++ VQC G +CWCVD G E+ G + G+ C +
Sbjct: 47 DEYVPQCSEDGSFQTVQCQNDGQSCWCVDSDGTEVPG-----SRQLGRPTACLSFCQLHK 101
Query: 366 QRKIIGRFFH---------CDHLGNYEKVQC--HGSVCYYADSSGKKI 476
QR ++ + + C GNY VQC C+ D+ G ++
Sbjct: 102 QRILLSSYINSTDALYLPQCQDSGNYAPVQCDLQQVQCWCVDTEGMEV 149
Score = 46.2 bits (108), Expect = 5e-05
Identities = 32/102 (31%), Positives = 46/102 (45%), Gaps = 10/102 (9%)
Frame = +3
Query: 156 LDARRLIKSGAMDVT----FPFCEDTGMYKPVQC--VGAACWCVDDSGDEIKGYITGIEK 317
L +R++ S ++ T P C+D+G Y PVQC CWCVD G E+ G +
Sbjct: 99 LHKQRILLSSYINSTDALYLPQCQDSGNYAPVQCDLQQVQCWCVDTEGMEVYG-----TR 153
Query: 318 SYGKTCNCAKDKHEYSQRKIIG----RFFHCDHLGNYEKVQC 431
G+ C + S+R + G CD G + VQC
Sbjct: 154 QQGRPTRCPRSCEIRSRRLLHGVGDKSPPQCDADGEFMPVQC 195
Score = 41.6 bits (96), Expect = 0.001
Identities = 36/109 (33%), Positives = 47/109 (43%), Gaps = 5/109 (4%)
Frame = +3
Query: 183 GAMDVTFPFCEDTGMYKPVQCVGAACWCVDDSGDEIKGYITGIEKSYGKTCNCAKDKHEY 362
G D+ P C TG Y Q G WCVD S E G T S C K
Sbjct: 1100 GPGDLFTPVCLQTGEYVRQQTSGTGAWCVDPSSGE--GVPTNTNSSAQCPGLCDALKSRV 1157
Query: 363 SQRKI-IGRFFHCDHL-GNYEKVQC---HGSVCYYADSSGKKIPTSPTV 494
RK+ +G C+ L G + VQC GS C+ +SG+++P + V
Sbjct: 1158 LSRKVGLGYTPVCEALDGGFSPVQCDLAQGS-CWCVLASGEEVPGTRVV 1205
Score = 41.2 bits (95), Expect = 0.002
Identities = 23/58 (39%), Positives = 30/58 (51%), Gaps = 1/58 (1%)
Frame = +3
Query: 204 PFCEDTGMYKPVQC-VGAACWCVDDSGDEIKGYITGIEKSYGKTCNCAKDKHEYSQRK 374
P C G Y+ VQC + CWCVD G EI G + G+ CAKD+ S+R+
Sbjct: 318 PSCHRDGHYQTVQCQMERMCWCVDAQGIEIPG-----TRQQGQPLFCAKDQSCASERQ 370
Score = 38.5 bits (88), Expect = 0.011
Identities = 19/55 (34%), Positives = 26/55 (47%), Gaps = 2/55 (3%)
Frame = +3
Query: 138 KCFKRHLDARRLIKSGAMDVTF--PFCEDTGMYKPVQCVGAACWCVDDSGDEIKG 296
KC K+ + L + +F P C G + PVQC + C+CVD G I G
Sbjct: 661 KCEKQRAQMQNLAGAQPAGSSFFVPTCTSEGYFLPVQCFNSECYCVDAEGQVIPG 715
Score = 38.1 bits (87), Expect = 0.015
Identities = 38/129 (29%), Positives = 55/129 (42%), Gaps = 16/129 (12%)
Frame = +3
Query: 204 PFCEDTGMYKPVQCVGAA--CWCVDDSGDEIKGYI-----------TGIEKSYGKTCNCA 344
P C G ++PVQC CWCVD G+ I G + T E S A
Sbjct: 1030 PQCNTIGGWEPVQCHPGTGQCWCVDGWGELIPGSLMARSSQMPQCPTSCELSRANGLISA 1089
Query: 345 KDKHEYSQRKIIGRFFH--CDHLGNYEKVQCHGSVCYYAD-SSGKKIPTSPTVHIAERDS 515
+ + + G F C G Y + Q G+ + D SSG+ +PT+ T A+
Sbjct: 1090 WKQAGHQRNPGPGDLFTPVCLQTGEYVRQQTSGTGAWCVDPSSGEGVPTN-TNSSAQCPG 1148
Query: 516 LKCD*IKNK 542
L CD +K++
Sbjct: 1149 L-CDALKSR 1156
Score = 35.4 bits (80), Expect = 0.095
Identities = 18/51 (35%), Positives = 26/51 (50%), Gaps = 2/51 (3%)
Frame = +3
Query: 381 GRFF--HCDHLGNYEKVQCHGSVCYYADSSGKKIPTSPTVHIAERDSLKCD 527
GRFF C G+YE +QC+ C+ +S GK++ S R KC+
Sbjct: 613 GRFFVPSCTAEGSYEDIQCYAGECWCVNSQGKEVEGSRVSGGHPRCPTKCE 663
>sp|P01266|THYG_HUMAN Thyroglobulin precursor
Length = 2768
Score = 51.2 bits (121), Expect = 2e-06
Identities = 31/102 (30%), Positives = 42/102 (41%), Gaps = 10/102 (9%)
Frame = +3
Query: 204 PFCEDTGMYKPVQCVGAACWCVDDSGDEIKGYITGIEKSYGKTCNCAKD--KHEYSQRKI 377
P C G Y+ VQC CWCV+ G E+ G + G C D K + +
Sbjct: 618 PSCTTEGSYEDVQCFSGECWCVNSWGKELPG-----SRVRGGQPRCPTDCEKQRARMQSL 672
Query: 378 IGR--------FFHCDHLGNYEKVQCHGSVCYYADSSGKKIP 479
+G C G++ VQC S CY D+ G+ IP
Sbjct: 673 MGSQPAGSTLFVPACTSEGHFLPVQCFNSECYCVDAEGQAIP 714
Score = 42.7 bits (99), Expect = 6e-04
Identities = 30/102 (29%), Positives = 46/102 (45%), Gaps = 10/102 (9%)
Frame = +3
Query: 156 LDARRLIKSGAMDVT----FPFCEDTGMYKPVQC--VGAACWCVDDSGDEIKGYITGIEK 317
L ++++ SG ++ T P C+D+G Y PVQC CWCVD G E+ G +
Sbjct: 98 LQKQQILLSGYINSTDTSYLPQCQDSGDYAPVQCDVQQVQCWCVDAEGMEVYG-----TR 152
Query: 318 SYGKTCNCAKDKHEYSQRKIIG----RFFHCDHLGNYEKVQC 431
G+ C + ++R + G C G + VQC
Sbjct: 153 QLGRPKRCPRSCEIRNRRLLHGVGDKSPPQCSAEGEFMPVQC 194
Score = 41.6 bits (96), Expect = 0.001
Identities = 30/126 (23%), Positives = 54/126 (42%), Gaps = 13/126 (10%)
Frame = +3
Query: 204 PFCEDTGMYKPVQCV--GAACWCVDDSGDEIKGYITGIEKSYGKTCNCAKDKHEYSQRKI 377
P C + G ++ VQC G +CWCV +G E+ G + G+ C Q+ +
Sbjct: 50 PQCAEDGSFQTVQCQNDGRSCWCVGANGSEVLG-----SRQPGRPVACLSFCQLQKQQIL 104
Query: 378 IGRFFH---------CDHLGNYEKVQC--HGSVCYYADSSGKKIPTSPTVHIAERDSLKC 524
+ + + C G+Y VQC C+ D+ G ++ + + +R C
Sbjct: 105 LSGYINSTDTSYLPQCQDSGDYAPVQCDVQQVQCWCVDAEGMEVYGTRQLGRPKRCPRSC 164
Query: 525 D*IKNK 542
+ I+N+
Sbjct: 165 E-IRNR 169
Score = 38.9 bits (89), Expect = 0.009
Identities = 24/92 (26%), Positives = 34/92 (36%), Gaps = 14/92 (15%)
Frame = +3
Query: 204 PFCEDTGMYKPVQCVGAACWCVDDSGDEIKGYITGIEKSYGKTCNCAKDKHEYSQRKIIG 383
P C G + PVQC + C+CVD G I G + I K C + R +
Sbjct: 685 PACTSEGHFLPVQCFNSECYCVDAEGQAIPGTRSAIGKPKKCPTPCQLQSEQAFLRTVQA 744
Query: 384 RFFH--------------CDHLGNYEKVQCHG 437
+ C G + +VQC+G
Sbjct: 745 LLSNSSMLPTLSDTYIPQCSTDGQWRQVQCNG 776
Score = 38.9 bits (89), Expect = 0.009
Identities = 20/50 (40%), Positives = 27/50 (54%), Gaps = 2/50 (4%)
Frame = +3
Query: 162 ARRLIKSGAMDVTFPFCEDTGMYKPVQCVGAA--CWCVDDSGDEIKGYIT 305
A L++SG P C+ G ++PVQC CWCVD+ G I G +T
Sbjct: 1018 ASALLRSGPY---MPQCDAFGSWEPVQCHAGTGHCWCVDEKGGFIPGSLT 1064
Score = 38.1 bits (87), Expect = 0.015
Identities = 33/101 (32%), Positives = 46/101 (45%), Gaps = 5/101 (4%)
Frame = +3
Query: 192 DVTFPFCEDTGMYKPVQCVGAACWCVDD-SGDEIKGYITGIEKSYGKTCNCAKDKHEYSQ 368
D+ P C +TG Y +Q GA WCVD SG+E++ + CN K S+
Sbjct: 1102 DLFVPACLETGEYARLQASGAGTWCVDPASGEELRPG-SSSSAQCPSLCNVLK-SGVLSR 1159
Query: 369 RKIIGRFFHC-DHLGNYEKVQC---HGSVCYYADSSGKKIP 479
R G C G + VQC GS C+ SG+++P
Sbjct: 1160 RVSPGYVPACRAEDGGFSPVQCDQAQGS-CWCVMDSGEEVP 1199
Score = 37.4 bits (85), Expect = 0.025
Identities = 20/58 (34%), Positives = 29/58 (50%), Gaps = 1/58 (1%)
Frame = +3
Query: 204 PFCEDTGMYKPVQC-VGAACWCVDDSGDEIKGYITGIEKSYGKTCNCAKDKHEYSQRK 374
P C G Y+ VQC CWCVD G E+ G + G+ +CA+ + S+R+
Sbjct: 317 PSCRRNGDYQAVQCQTEGPCWCVDAQGKEMHG-----TRQQGEPPSCAEGQSCASERQ 369
Score = 37.4 bits (85), Expect = 0.025
Identities = 22/70 (31%), Positives = 37/70 (52%), Gaps = 4/70 (5%)
Frame = +3
Query: 204 PFCE-DTGMYKPVQCVGA--ACWCVDDSGDEIKG-YITGIEKSYGKTCNCAKDKHEYSQR 371
P C + G + PVQC A +CWCV DSG+E+ G +TG + + C + ++
Sbjct: 1167 PACRAEDGGFSPVQCDQAQGSCWCVMDSGEEVPGTRVTGGQPA----CESPRCPLPFNAS 1222
Query: 372 KIIGRFFHCD 401
+++G C+
Sbjct: 1223 EVVGGTILCE 1232
Score = 31.6 bits (70), Expect = 1.4
Identities = 13/30 (43%), Positives = 18/30 (60%)
Frame = +3
Query: 396 CDHLGNYEKVQCHGSVCYYADSSGKKIPTS 485
C G+YE VQC C+ +S GK++P S
Sbjct: 620 CTTEGSYEDVQCFSGECWCVNSWGKELPGS 649
Score = 31.6 bits (70), Expect = 1.4
Identities = 15/34 (44%), Positives = 18/34 (52%), Gaps = 2/34 (5%)
Frame = +3
Query: 396 CDHLGNYEKVQCHGSV--CYYADSSGKKIPTSPT 491
CD G++E VQCH C+ D G IP S T
Sbjct: 1031 CDAFGSWEPVQCHAGTGHCWCVDEKGGFIPGSLT 1064
>sp|P81439|EQST_ACTEQ Equistatin
Length = 199
Score = 48.1 bits (113), Expect = 1e-05
Identities = 34/113 (30%), Positives = 54/113 (47%), Gaps = 14/113 (12%)
Frame = +3
Query: 180 SGAMDVTFPFCEDTGMYKPVQCVGAA--CWCVDDSGDEIKGYITGIEKSYGKTCNCAKDK 353
SG + P C++TG ++ QC G+ CWCVD+ G EI G T I S +C++ K
Sbjct: 14 SGLIGAYVPQCKETGEFEEKQCWGSTGYCWCVDEDGKEILG--TKIRGS----PDCSRRK 67
Query: 354 HEYSQRKIIGRFF----------HCDHLGNYEKVQCHGS--VCYYADSSGKKI 476
+ +++ C G++++VQC S CY D GK++
Sbjct: 68 AALTLCQMMQAIIVNVPGWCGPPSCKADGSFDEVQCCASNGECYCVDKKGKEL 120
Score = 44.7 bits (104), Expect = 2e-04
Identities = 32/103 (31%), Positives = 46/103 (44%), Gaps = 13/103 (12%)
Frame = +3
Query: 27 TCIFSSKLEEFDVCGNNDQCNVGLICDEVCKE-----DNNAPKCFKRHL----DARRLIK 179
+C +E C +N +C D+ KE P C +RHL +AR
Sbjct: 91 SCKADGSFDEVQCCASNGEC---YCVDKKGKELEGTRQKGRPSC-ERHLSPCEEARLQAH 146
Query: 180 SGAMDVTF--PFCEDTGMYKPVQCVGAA--CWCVDDSGDEIKG 296
S ++ V P C + G Y PVQC + CWCVD+ G ++ G
Sbjct: 147 SNSLRVGMFVPQCLEDGSYNPVQCWPSTGYCWCVDEGGVKVPG 189
>sp|O88322|NID2_MOUSE Nidogen-2 precursor (NID-2) (Entactin-2)
Length = 1403
Score = 47.4 bits (111), Expect = 2e-05
Identities = 33/118 (27%), Positives = 51/118 (43%), Gaps = 24/118 (20%)
Frame = +3
Query: 195 VTFPFCEDTGMYKPVQCVGAA--CWCVDDSGDEIKGYITGIEKSYGKTCNCAKDKHEYSQ 368
+ P C+D G + P+QC G+ CWCVD +G E + G + G T E +Q
Sbjct: 986 IHIPQCDDQGNFVPLQCHGSTGFCWCVDRNGHE----VPGTQTPPGSTPPHCGPPPEPTQ 1041
Query: 369 --RKIIGRFF------------------HCDHLGNYEKVQCHG--SVCYYADSSGKKI 476
R + R+ CD LG++ +QCHG C+ D G+++
Sbjct: 1042 RPRTVCERWRESLLEHYGGTPRDDQYVPQCDDLGHFIPLQCHGKSDFCWCVDKDGREL 1099
Score = 40.4 bits (93), Expect = 0.003
Identities = 17/37 (45%), Positives = 23/37 (62%), Gaps = 2/37 (5%)
Frame = +3
Query: 192 DVTFPFCEDTGMYKPVQCVGAA--CWCVDDSGDEIKG 296
D P C+D G + P+QC G + CWCVD G E++G
Sbjct: 1065 DQYVPQCDDLGHFIPLQCHGKSDFCWCVDKDGRELQG 1101
Score = 36.2 bits (82), Expect = 0.056
Identities = 18/52 (34%), Positives = 28/52 (53%), Gaps = 2/52 (3%)
Frame = +3
Query: 342 AKDKHEYSQRKIIGRFFHCDHLGNYEKVQCHGSV--CYYADSSGKKIPTSPT 491
A+ +H Y +I CD GN+ +QCHGS C+ D +G ++P + T
Sbjct: 975 AQTQHAYPGSRI--HIPQCDDQGNFVPLQCHGSTGFCWCVDRNGHEVPGTQT 1024
>sp|Q14112|NID2_HUMAN Nidogen-2 precursor (NID-2) (Osteonidogen)
Length = 1375
Score = 47.0 bits (110), Expect = 3e-05
Identities = 36/134 (26%), Positives = 55/134 (41%), Gaps = 24/134 (17%)
Frame = +3
Query: 147 KRHLDARRLIKSGAMDVTFPFCEDTGMYKPVQCVGAA--CWCVDDSGDEIKGYITGIEKS 320
+RH A+ + P C++ G + P+QC G+ CWCVD G E + G +
Sbjct: 944 QRHAQAQYAYPGARFHI--PQCDEQGNFLPLQCHGSTGFCWCVDPDGHE----VPGTQTP 997
Query: 321 YGKTCNCAKDKHEYSQR--KIIGRFF------------------HCDHLGNYEKVQCHG- 437
G T E +QR I R+ CD LG++ +QCHG
Sbjct: 998 PGSTPPHCGPSPEPTQRPPTICERWRENLLEHYGGTPRDDQYVPQCDDLGHFIPLQCHGK 1057
Query: 438 -SVCYYADSSGKKI 476
C+ D G+++
Sbjct: 1058 SDFCWCVDKDGREV 1071
Score = 40.8 bits (94), Expect = 0.002
Identities = 17/37 (45%), Positives = 23/37 (62%), Gaps = 2/37 (5%)
Frame = +3
Query: 192 DVTFPFCEDTGMYKPVQCVGAA--CWCVDDSGDEIKG 296
D P C+D G + P+QC G + CWCVD G E++G
Sbjct: 1037 DQYVPQCDDLGHFIPLQCHGKSDFCWCVDKDGREVQG 1073
Score = 38.1 bits (87), Expect = 0.015
Identities = 19/54 (35%), Positives = 28/54 (51%), Gaps = 5/54 (9%)
Frame = +3
Query: 345 KDKHEYSQRKIIGRFFH---CDHLGNYEKVQCHGSV--CYYADSSGKKIPTSPT 491
+ +H +Q G FH CD GN+ +QCHGS C+ D G ++P + T
Sbjct: 943 QQRHAQAQYAYPGARFHIPQCDEQGNFLPLQCHGSTGFCWCVDPDGHEVPGTQT 996
>sp|Q8BKV0|TICN3_MOUSE Testican-3 precursor (SPARC/osteonectin, CWCV, and Kazal-like
domains proteoglycan 3)
Length = 436
Score = 44.7 bits (104), Expect = 2e-04
Identities = 26/79 (32%), Positives = 37/79 (46%), Gaps = 4/79 (5%)
Frame = +3
Query: 72 NNDQCNVGLICDEVCKEDNNAPKCFKR--HLDARRLIKSGAMDVTFPFCEDTGMYKPVQC 245
NN+ C C + P C ++ R+ IK + P C++ G YKP QC
Sbjct: 302 NNEWC--------YCFQRQQDPPCHTELSNIQKRQGIKK-LLGQYIPLCDEDGYYKPTQC 352
Query: 246 VGAA--CWCVDDSGDEIKG 296
G+ CWCVD G+E+ G
Sbjct: 353 HGSVGQCWCVDRYGNEVVG 371
Score = 33.5 bits (75), Expect = 0.36
Identities = 17/49 (34%), Positives = 28/49 (57%), Gaps = 3/49 (6%)
Frame = +3
Query: 369 RKIIGRFFH-CDHLGNYEKVQCHGSV--CYYADSSGKKIPTSPTVHIAE 506
+K++G++ CD G Y+ QCHGSV C+ D G ++ S +A+
Sbjct: 331 KKLLGQYIPLCDEDGYYKPTQCHGSVGQCWCVDRYGNEVVGSRINGVAD 379
>sp|Q9BQ16|TICN3_HUMAN Testican-3 precursor (SPARC/osteonectin, CWCV, and Kazal-like
domains proteoglycan 3)
Length = 436
Score = 44.3 bits (103), Expect = 2e-04
Identities = 17/33 (51%), Positives = 22/33 (66%), Gaps = 2/33 (6%)
Frame = +3
Query: 204 PFCEDTGMYKPVQCVGAA--CWCVDDSGDEIKG 296
P C++ G YKP QC G+ CWCVD G+E+ G
Sbjct: 339 PLCDEDGYYKPTQCHGSVGQCWCVDRYGNEVMG 371
Score = 33.5 bits (75), Expect = 0.36
Identities = 17/49 (34%), Positives = 28/49 (57%), Gaps = 3/49 (6%)
Frame = +3
Query: 369 RKIIGRFFH-CDHLGNYEKVQCHGSV--CYYADSSGKKIPTSPTVHIAE 506
+K++G++ CD G Y+ QCHGSV C+ D G ++ S +A+
Sbjct: 331 KKLLGQYIPLCDEDGYYKPTQCHGSVGQCWCVDRYGNEVMGSRINGVAD 379
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 64,062,542
Number of Sequences: 369166
Number of extensions: 1358768
Number of successful extensions: 3747
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3489
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3691
length of database: 68,354,980
effective HSP length: 104
effective length of database: 49,142,540
effective search space used: 3931403200
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)