Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_015_D05
(650 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q60HC9|TPIS_MACFA Triosephosphate isomerase (TIM) (Trios... 238 1e-62
sp|P00939|TPIS_RABIT Triosephosphate isomerase (TIM) (Trios... 237 2e-62
sp|P60174|TPIS_HUMAN Triosephosphate isomerase (TIM) (Trios... 236 3e-62
sp|P54714|TPIS_CANFA Triosephosphate isomerase (TIM) (Trios... 236 3e-62
sp|P00940|TPIS_CHICK Triosephosphate isomerase (TIM) (Trios... 236 4e-62
sp|P48500|TPIS_RAT Triosephosphate isomerase (TIM) (Triose-... 236 5e-62
sp|P17751|TPIS_MOUSE Triosephosphate isomerase (TIM) (Trios... 235 7e-62
sp|Q589R5|TPIS_ORYLA Triosephosphate isomerase (TIM) (Trios... 226 4e-59
sp|Q9GTX8|TPIS_TAESO Triosephosphate isomerase (TIM) (Trios... 226 5e-59
sp|P46226|TPIS_SECCE Triosephosphate isomerase, cytosolic (... 218 8e-57
>sp|Q60HC9|TPIS_MACFA Triosephosphate isomerase (TIM) (Triose-phosphate isomerase)
sp|P15426|TPIS_MACMU Triosephosphate isomerase (TIM) (Triose-phosphate isomerase)
Length = 249
Score = 238 bits (606), Expect = 1e-62
Identities = 114/151 (75%), Positives = 130/151 (86%)
Frame = +1
Query: 19 ERRHVFGESDHLIGEKVKHALESGLSIIPCIGEKLDERESNKTNEVCFRQLKEIAANIKD 198
ERRHVFGESD LIG+KV HAL GL +I CIGEKLDERE+ T +V F Q K IA N+KD
Sbjct: 98 ERRHVFGESDELIGQKVAHALAEGLGVIACIGEKLDEREAGITEKVVFEQTKVIADNVKD 157
Query: 199 WTRVVIAYEPVWAIGTGKTASPAQAQEVHKCVRDWLKTNVSEEVAKTTRILYGGSVTSGN 378
W++VV+AYEPVWAIGTGKTA+P QAQEVH+ +R WLK+NVSE VA++TRI+YGGSVT
Sbjct: 158 WSKVVLAYEPVWAIGTGKTATPQQAQEVHEKLRGWLKSNVSEAVAQSTRIIYGGSVTGAT 217
Query: 379 CKELASQPDVDGFLVGGASLKPEFIDIINAK 471
CKELASQPDVDGFLVGGASLKPEF+DIINAK
Sbjct: 218 CKELASQPDVDGFLVGGASLKPEFVDIINAK 248
>sp|P00939|TPIS_RABIT Triosephosphate isomerase (TIM) (Triose-phosphate isomerase)
Length = 248
Score = 237 bits (604), Expect = 2e-62
Identities = 113/151 (74%), Positives = 130/151 (86%)
Frame = +1
Query: 19 ERRHVFGESDHLIGEKVKHALESGLSIIPCIGEKLDERESNKTNEVCFRQLKEIAANIKD 198
ERRHVFGESD LIG+KV HAL GL +I CIGEKLDERE+ T +V F Q K IA N+KD
Sbjct: 97 ERRHVFGESDELIGQKVAHALSEGLGVIACIGEKLDEREAGITEKVVFEQTKVIADNVKD 156
Query: 199 WTRVVIAYEPVWAIGTGKTASPAQAQEVHKCVRDWLKTNVSEEVAKTTRILYGGSVTSGN 378
W++VV+AYEPVWAIGTGKTA+P QAQEVH+ +R WLK+NVS+ VA++TRI+YGGSVT
Sbjct: 157 WSKVVLAYEPVWAIGTGKTATPQQAQEVHEKLRGWLKSNVSDAVAQSTRIIYGGSVTGAT 216
Query: 379 CKELASQPDVDGFLVGGASLKPEFIDIINAK 471
CKELASQPDVDGFLVGGASLKPEF+DIINAK
Sbjct: 217 CKELASQPDVDGFLVGGASLKPEFVDIINAK 247
>sp|P60174|TPIS_HUMAN Triosephosphate isomerase (TIM) (Triose-phosphate isomerase)
sp|P60175|TPIS_PANTR Triosephosphate isomerase (TIM) (Triose-phosphate isomerase)
Length = 249
Score = 236 bits (603), Expect = 3e-62
Identities = 113/151 (74%), Positives = 130/151 (86%)
Frame = +1
Query: 19 ERRHVFGESDHLIGEKVKHALESGLSIIPCIGEKLDERESNKTNEVCFRQLKEIAANIKD 198
ERRHVFGESD LIG+KV HAL GL +I CIGEKLDERE+ T +V F Q K IA N+KD
Sbjct: 98 ERRHVFGESDELIGQKVAHALAEGLGVIACIGEKLDEREAGITEKVVFEQTKVIADNVKD 157
Query: 199 WTRVVIAYEPVWAIGTGKTASPAQAQEVHKCVRDWLKTNVSEEVAKTTRILYGGSVTSGN 378
W++VV+AYEPVWAIGTGKTA+P QAQEVH+ +R WLK+NVS+ VA++TRI+YGGSVT
Sbjct: 158 WSKVVLAYEPVWAIGTGKTATPQQAQEVHEKLRGWLKSNVSDAVAQSTRIIYGGSVTGAT 217
Query: 379 CKELASQPDVDGFLVGGASLKPEFIDIINAK 471
CKELASQPDVDGFLVGGASLKPEF+DIINAK
Sbjct: 218 CKELASQPDVDGFLVGGASLKPEFVDIINAK 248
>sp|P54714|TPIS_CANFA Triosephosphate isomerase (TIM) (Triose-phosphate isomerase)
Length = 249
Score = 236 bits (603), Expect = 3e-62
Identities = 113/151 (74%), Positives = 130/151 (86%)
Frame = +1
Query: 19 ERRHVFGESDHLIGEKVKHALESGLSIIPCIGEKLDERESNKTNEVCFRQLKEIAANIKD 198
ERRHVFGESD LIG+KV HAL GL +I CIGEKLDERE+ T +V F Q K IA N+KD
Sbjct: 98 ERRHVFGESDELIGQKVAHALAEGLGVIACIGEKLDEREAGITEKVVFEQTKVIADNVKD 157
Query: 199 WTRVVIAYEPVWAIGTGKTASPAQAQEVHKCVRDWLKTNVSEEVAKTTRILYGGSVTSGN 378
W++VV+AYEPVWAIGTGKTA+P QAQEVH+ +R WLK+NVS+ VA++TRI+YGGSVT
Sbjct: 158 WSKVVLAYEPVWAIGTGKTATPQQAQEVHEKLRGWLKSNVSDAVAQSTRIIYGGSVTGAT 217
Query: 379 CKELASQPDVDGFLVGGASLKPEFIDIINAK 471
CKELASQPDVDGFLVGGASLKPEF+DIINAK
Sbjct: 218 CKELASQPDVDGFLVGGASLKPEFVDIINAK 248
>sp|P00940|TPIS_CHICK Triosephosphate isomerase (TIM) (Triose-phosphate isomerase)
Length = 248
Score = 236 bits (602), Expect = 4e-62
Identities = 113/151 (74%), Positives = 131/151 (86%)
Frame = +1
Query: 19 ERRHVFGESDHLIGEKVKHALESGLSIIPCIGEKLDERESNKTNEVCFRQLKEIAANIKD 198
ERRHVFGESD LIG+KV HAL GL +I CIGEKLDERE+ T +V F Q K IA N+KD
Sbjct: 97 ERRHVFGESDELIGQKVAHALAEGLGVIACIGEKLDEREAGITEKVVFEQTKAIADNVKD 156
Query: 199 WTRVVIAYEPVWAIGTGKTASPAQAQEVHKCVRDWLKTNVSEEVAKTTRILYGGSVTSGN 378
W++VV+AYEPVWAIGTGKTA+P QAQEVH+ +R WLK++VS+ VA++TRI+YGGSVT GN
Sbjct: 157 WSKVVLAYEPVWAIGTGKTATPQQAQEVHEKLRGWLKSHVSDAVAQSTRIIYGGSVTGGN 216
Query: 379 CKELASQPDVDGFLVGGASLKPEFIDIINAK 471
CKELASQ DVDGFLVGGASLKPEF+DIINAK
Sbjct: 217 CKELASQHDVDGFLVGGASLKPEFVDIINAK 247
>sp|P48500|TPIS_RAT Triosephosphate isomerase (TIM) (Triose-phosphate isomerase)
Length = 249
Score = 236 bits (601), Expect = 5e-62
Identities = 113/151 (74%), Positives = 127/151 (84%)
Frame = +1
Query: 19 ERRHVFGESDHLIGEKVKHALESGLSIIPCIGEKLDERESNKTNEVCFRQLKEIAANIKD 198
ERRH+FGESD LIG+KV HAL GL +I CIGEKLDERE+ T +V F Q K IA N+KD
Sbjct: 98 ERRHIFGESDELIGQKVNHALSEGLEVIACIGEKLDEREAGITEKVVFEQTKAIADNVKD 157
Query: 199 WTRVVIAYEPVWAIGTGKTASPAQAQEVHKCVRDWLKTNVSEEVAKTTRILYGGSVTSGN 378
W +VV+AYEPVWAIGTGKTA+P QAQEVH+ +R WLK NVSE VA+ TRI+YGGSVT
Sbjct: 158 WCKVVLAYEPVWAIGTGKTATPQQAQEVHEKLRGWLKCNVSEGVAQCTRIIYGGSVTGAT 217
Query: 379 CKELASQPDVDGFLVGGASLKPEFIDIINAK 471
CKELASQPDVDGFLVGGASLKPEF+DIINAK
Sbjct: 218 CKELASQPDVDGFLVGGASLKPEFVDIINAK 248
>sp|P17751|TPIS_MOUSE Triosephosphate isomerase (TIM) (Triose-phosphate isomerase)
Length = 249
Score = 235 bits (600), Expect = 7e-62
Identities = 112/151 (74%), Positives = 130/151 (86%)
Frame = +1
Query: 19 ERRHVFGESDHLIGEKVKHALESGLSIIPCIGEKLDERESNKTNEVCFRQLKEIAANIKD 198
ERRHVFGESD LIG+KV HAL GL +I CIGEKLDERE+ T +V F Q K IA N+KD
Sbjct: 98 ERRHVFGESDELIGQKVSHALAEGLGVIACIGEKLDEREAGITEKVVFEQTKVIADNVKD 157
Query: 199 WTRVVIAYEPVWAIGTGKTASPAQAQEVHKCVRDWLKTNVSEEVAKTTRILYGGSVTSGN 378
W++VV+AYEPVWAIGTGKTA+P QAQEVH+ +R WLK+NV++ VA++TRI+YGGSVT
Sbjct: 158 WSKVVLAYEPVWAIGTGKTATPQQAQEVHEKLRGWLKSNVNDGVAQSTRIIYGGSVTGAT 217
Query: 379 CKELASQPDVDGFLVGGASLKPEFIDIINAK 471
CKELASQPDVDGFLVGGASLKPEF+DIINAK
Sbjct: 218 CKELASQPDVDGFLVGGASLKPEFVDIINAK 248
>sp|Q589R5|TPIS_ORYLA Triosephosphate isomerase (TIM) (Triose-phosphate isomerase)
Length = 248
Score = 226 bits (576), Expect = 4e-59
Identities = 107/151 (70%), Positives = 128/151 (84%)
Frame = +1
Query: 19 ERRHVFGESDHLIGEKVKHALESGLSIIPCIGEKLDERESNKTNEVCFRQLKEIAANIKD 198
ERRHVFGE+D LIG+KV HALES LS+I CIGEKL+ERE+ T +V F Q + IA N+ D
Sbjct: 97 ERRHVFGENDELIGQKVAHALESDLSVIACIGEKLEEREAGTTEDVIFAQTQVIAENVMD 156
Query: 199 WTRVVIAYEPVWAIGTGKTASPAQAQEVHKCVRDWLKTNVSEEVAKTTRILYGGSVTSGN 378
W +VV+AYEPVWAIGTGKTA+P QAQEVH+ +R W + N+SEEV+ + RI+YGGSVT+ N
Sbjct: 157 WEKVVLAYEPVWAIGTGKTATPEQAQEVHEKLRAWFRANISEEVSDSLRIIYGGSVTAAN 216
Query: 379 CKELASQPDVDGFLVGGASLKPEFIDIINAK 471
C+ELASQ DVDGFLVGGASLKPEFIDIINA+
Sbjct: 217 CRELASQTDVDGFLVGGASLKPEFIDIINAR 247
>sp|Q9GTX8|TPIS_TAESO Triosephosphate isomerase (TIM) (Triose-phosphate isomerase)
Length = 250
Score = 226 bits (575), Expect = 5e-59
Identities = 108/154 (70%), Positives = 128/154 (83%), Gaps = 3/154 (1%)
Frame = +1
Query: 19 ERRHVFGESDHLIGEKVKHALESGLSIIPCIGEKLDERESNKTNEVCFRQLKEIAANIKD 198
ERRH+FGES+ LIGEKVKHAL+SGL++IPCIGE L ERE+ KTN+VCF Q+ IA N+
Sbjct: 96 ERRHIFGESNELIGEKVKHALDSGLNVIPCIGELLSEREAGKTNDVCFAQMDAIAKNVPS 155
Query: 199 ---WTRVVIAYEPVWAIGTGKTASPAQAQEVHKCVRDWLKTNVSEEVAKTTRILYGGSVT 369
W +VVIAYEPVWAIGTGKTA+PAQAQEVHK VRDW++ +V +A RILYGGSVT
Sbjct: 156 KEAWDKVVIAYEPVWAIGTGKTATPAQAQEVHKVVRDWIRKHVDAGIADKVRILYGGSVT 215
Query: 370 SGNCKELASQPDVDGFLVGGASLKPEFIDIINAK 471
+ N K+L +QPDVDGFLVGGASLKP+FI IINA+
Sbjct: 216 ASNAKDLGTQPDVDGFLVGGASLKPDFITIINAR 249
>sp|P46226|TPIS_SECCE Triosephosphate isomerase, cytosolic (TIM) (Triose-phosphate
isomerase)
Length = 253
Score = 218 bits (556), Expect = 8e-57
Identities = 106/150 (70%), Positives = 121/150 (80%)
Frame = +1
Query: 19 ERRHVFGESDHLIGEKVKHALESGLSIIPCIGEKLDERESNKTNEVCFRQLKEIAANIKD 198
ERR + ES +GEKV +AL GL +I C+GE L++RE+ T EV Q K IA IKD
Sbjct: 98 ERRSLLAESSEFVGEKVAYALAQGLKVIACVGETLEQREAGSTMEVVAEQTKAIADKIKD 157
Query: 199 WTRVVIAYEPVWAIGTGKTASPAQAQEVHKCVRDWLKTNVSEEVAKTTRILYGGSVTSGN 378
WT VV+AYEPVWAIGTGK ASPAQAQEVH +RDWLKTNVS EVA++TRI+YGGSVT +
Sbjct: 158 WTNVVVAYEPVWAIGTGKVASPAQAQEVHANLRDWLKTNVSPEVAESTRIIYGGSVTGAS 217
Query: 379 CKELASQPDVDGFLVGGASLKPEFIDIINA 468
CKELA+QPDVDGFLVGGASLKPEFIDIINA
Sbjct: 218 CKELAAQPDVDGFLVGGASLKPEFIDIINA 247
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 59,987,903
Number of Sequences: 369166
Number of extensions: 1033349
Number of successful extensions: 3175
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 2915
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 2961
length of database: 68,354,980
effective HSP length: 106
effective length of database: 48,773,070
effective search space used: 5365037700
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)