Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_015_C10
(419 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P26932|CNN1_CHICK Calponin-1 (Calponin, smooth muscle) 69 3e-12
sp|P37397|CNN3_RAT Calponin-3 (Calponin, acidic isoform) (C... 66 3e-11
sp|Q15417|CNN3_HUMAN Calponin-3 (Calponin, acidic isoform) 65 4e-11
sp|Q9DAW9|CNN3_MOUSE Calponin-3 (Calponin, acidic isoform) 65 4e-11
sp|Q08290|CNN1_RAT Calponin-1 (Calponin H1, smooth muscle) ... 64 1e-10
sp|Q08092|CNN1_PIG Calponin-1 (Calponin H1, smooth muscle) ... 64 1e-10
sp|P51911|CNN1_HUMAN Calponin-1 (Calponin H1, smooth muscle... 64 1e-10
sp|Q08091|CNN1_MOUSE Calponin-1 (Calponin H1, smooth muscle... 64 1e-10
sp|Q08094|CNN2_PIG Calponin-2 (Calponin H2, smooth muscle) ... 62 5e-10
sp|Q99439|CNN2_HUMAN Calponin-2 (Calponin H2, smooth muscle... 48 7e-06
>sp|P26932|CNN1_CHICK Calponin-1 (Calponin, smooth muscle)
Length = 292
Score = 69.3 bits (168), Expect = 3e-12
Identities = 51/110 (46%), Positives = 65/110 (59%), Gaps = 3/110 (2%)
Frame = +1
Query: 4 GLQAGSNKGASQSGM-RIGTQRFINDVSTGVEMSDEGKTVIGLQAGSNKGATQAGMRI-G 177
GLQ G+NK ASQ GM GT+R + D G + + T I LQ G+NKGA+QAGM G
Sbjct: 165 GLQMGTNKFASQQGMTAYGTRRHLYDPKLGTDQPLDQAT-ISLQMGTNKGASQAGMTAPG 223
Query: 178 TQRFINDVSTGVEMSDEGKQTIGLQMGPDKSQVDSQSGMS-FGAQRHITD 324
T+R I + S G+E D IGLQMG +K SQ GM+ +G R + D
Sbjct: 224 TKRQIFEPSLGMERCD--TNIIGLQMGSNKGA--SQQGMTVYGLPRQVYD 269
Score = 47.4 bits (111), Expect = 1e-05
Identities = 32/73 (43%), Positives = 45/73 (61%), Gaps = 2/73 (2%)
Frame = +1
Query: 106 EGKTVIGLQAGSNKGATQAGM-RIGTQRFINDVSTGVEMSDEGKQTIGLQMGPDKSQVDS 282
EG+ +IGLQ G+NK A+Q GM GT+R + D G + + + TI LQMG +K S
Sbjct: 159 EGRNIIGLQMGTNKFASQQGMTAYGTRRHLYDPKLGTDQPLD-QATISLQMGTNKGA--S 215
Query: 283 QSGMSF-GAQRHI 318
Q+GM+ G +R I
Sbjct: 216 QAGMTAPGTKRQI 228
>sp|P37397|CNN3_RAT Calponin-3 (Calponin, acidic isoform) (Calponin, non-muscle
isoform)
Length = 330
Score = 65.9 bits (159), Expect = 3e-11
Identities = 50/110 (45%), Positives = 65/110 (59%), Gaps = 3/110 (2%)
Frame = +1
Query: 4 GLQAGSNKGASQSGM-RIGTQRFINDVSTGVEMSDEGKTVIGLQAGSNKGATQAGMRI-G 177
GLQ G+NK ASQ+GM GT+R + D + + +T I LQ G+NKGA+QAGM G
Sbjct: 165 GLQMGTNKCASQAGMTAYGTRRHLYDPKMQTDKPFD-QTTISLQMGTNKGASQAGMSAPG 223
Query: 178 TQRFINDVSTGVEMSDEGKQTIGLQMGPDKSQVDSQSGMS-FGAQRHITD 324
T+R I D ++ D TI LQMG +K V SQ GMS +G R + D
Sbjct: 224 TRRDIYDQKLTLQPVD--NSTISLQMGTNK--VASQKGMSVYGLGRQVYD 269
Score = 47.0 bits (110), Expect = 2e-05
Identities = 34/74 (45%), Positives = 46/74 (62%), Gaps = 2/74 (2%)
Frame = +1
Query: 109 GKTVIGLQAGSNKGATQAGM-RIGTQRFINDVSTGVEMSDEGKQTIGLQMGPDKSQVDSQ 285
G++VIGLQ G+NK A+QAGM GT+R + D + + + TI LQMG +K SQ
Sbjct: 160 GQSVIGLQMGTNKCASQAGMTAYGTRRHLYDPKMQTDKPFD-QTTISLQMGTNKGA--SQ 216
Query: 286 SGMSF-GAQRHITD 324
+GMS G +R I D
Sbjct: 217 AGMSAPGTRRDIYD 230
>sp|Q15417|CNN3_HUMAN Calponin-3 (Calponin, acidic isoform)
Length = 329
Score = 65.5 bits (158), Expect = 4e-11
Identities = 50/110 (45%), Positives = 65/110 (59%), Gaps = 3/110 (2%)
Frame = +1
Query: 4 GLQAGSNKGASQSGM-RIGTQRFINDVSTGVEMSDEGKTVIGLQAGSNKGATQAGMRI-G 177
GLQ G+NK ASQ+GM GT+R + D + + +T I LQ G+NKGA+QAGM G
Sbjct: 165 GLQMGTNKCASQAGMTAYGTRRHLYDPKMQTDKPFD-QTTISLQMGTNKGASQAGMLAPG 223
Query: 178 TQRFINDVSTGVEMSDEGKQTIGLQMGPDKSQVDSQSGMS-FGAQRHITD 324
T+R I D ++ D TI LQMG +K V SQ GMS +G R + D
Sbjct: 224 TRRDIYDQKLTLQPVD--NSTISLQMGTNK--VASQKGMSVYGLGRQVYD 269
Score = 45.1 bits (105), Expect = 6e-05
Identities = 33/74 (44%), Positives = 46/74 (62%), Gaps = 2/74 (2%)
Frame = +1
Query: 109 GKTVIGLQAGSNKGATQAGM-RIGTQRFINDVSTGVEMSDEGKQTIGLQMGPDKSQVDSQ 285
G++VIGLQ G+NK A+QAGM GT+R + D + + + TI LQMG +K SQ
Sbjct: 160 GQSVIGLQMGTNKCASQAGMTAYGTRRHLYDPKMQTDKPFD-QTTISLQMGTNKGA--SQ 216
Query: 286 SGM-SFGAQRHITD 324
+GM + G +R I D
Sbjct: 217 AGMLAPGTRRDIYD 230
>sp|Q9DAW9|CNN3_MOUSE Calponin-3 (Calponin, acidic isoform)
Length = 330
Score = 65.5 bits (158), Expect = 4e-11
Identities = 50/110 (45%), Positives = 65/110 (59%), Gaps = 3/110 (2%)
Frame = +1
Query: 4 GLQAGSNKGASQSGM-RIGTQRFINDVSTGVEMSDEGKTVIGLQAGSNKGATQAGMRI-G 177
GLQ G+NK ASQ+GM GT+R + D + + +T I LQ G+NKGA+QAGM G
Sbjct: 165 GLQMGTNKCASQAGMTAYGTRRHLYDPKMQTDKPFD-QTTISLQMGTNKGASQAGMLAPG 223
Query: 178 TQRFINDVSTGVEMSDEGKQTIGLQMGPDKSQVDSQSGMS-FGAQRHITD 324
T+R I D ++ D TI LQMG +K V SQ GMS +G R + D
Sbjct: 224 TRRDIYDQKLTLQPVD--NSTISLQMGTNK--VASQKGMSVYGLGRQVYD 269
Score = 45.1 bits (105), Expect = 6e-05
Identities = 33/74 (44%), Positives = 46/74 (62%), Gaps = 2/74 (2%)
Frame = +1
Query: 109 GKTVIGLQAGSNKGATQAGM-RIGTQRFINDVSTGVEMSDEGKQTIGLQMGPDKSQVDSQ 285
G++VIGLQ G+NK A+QAGM GT+R + D + + + TI LQMG +K SQ
Sbjct: 160 GQSVIGLQMGTNKCASQAGMTAYGTRRHLYDPKMQTDKPFD-QTTISLQMGTNKGA--SQ 216
Query: 286 SGM-SFGAQRHITD 324
+GM + G +R I D
Sbjct: 217 AGMLAPGTRRDIYD 230
>sp|Q08290|CNN1_RAT Calponin-1 (Calponin H1, smooth muscle) (Basic calponin)
Length = 297
Score = 63.9 bits (154), Expect = 1e-10
Identities = 48/110 (43%), Positives = 63/110 (57%), Gaps = 3/110 (2%)
Frame = +1
Query: 4 GLQAGSNKGASQSGM-RIGTQRFINDVSTGVEMSDEGKTVIGLQAGSNKGATQAGMRI-G 177
GLQ G+NK ASQ GM GT+R + D G + + T I LQ G+NKGA+QAGM G
Sbjct: 165 GLQMGTNKFASQQGMTAYGTRRHLYDPKLGTDQPLDQAT-ISLQMGTNKGASQAGMTAPG 223
Query: 178 TQRFINDVSTGVEMSDEGKQTIGLQMGPDKSQVDSQSGMS-FGAQRHITD 324
T+R I + G+E D + LQMG +K SQ GM+ +G R + D
Sbjct: 224 TKRQIFEPGLGMEHCD--TLNVSLQMGSNKGA--SQRGMTVYGLPRQVYD 269
Score = 47.4 bits (111), Expect = 1e-05
Identities = 32/73 (43%), Positives = 45/73 (61%), Gaps = 2/73 (2%)
Frame = +1
Query: 106 EGKTVIGLQAGSNKGATQAGM-RIGTQRFINDVSTGVEMSDEGKQTIGLQMGPDKSQVDS 282
EG+ +IGLQ G+NK A+Q GM GT+R + D G + + + TI LQMG +K S
Sbjct: 159 EGRNIIGLQMGTNKFASQQGMTAYGTRRHLYDPKLGTDQPLD-QATISLQMGTNKGA--S 215
Query: 283 QSGMSF-GAQRHI 318
Q+GM+ G +R I
Sbjct: 216 QAGMTAPGTKRQI 228
>sp|Q08092|CNN1_PIG Calponin-1 (Calponin H1, smooth muscle) (Basic calponin)
Length = 297
Score = 63.9 bits (154), Expect = 1e-10
Identities = 48/110 (43%), Positives = 63/110 (57%), Gaps = 3/110 (2%)
Frame = +1
Query: 4 GLQAGSNKGASQSGM-RIGTQRFINDVSTGVEMSDEGKTVIGLQAGSNKGATQAGMRI-G 177
GLQ G+NK ASQ GM GT+R + D G + + T I LQ G+NKGA+QAGM G
Sbjct: 165 GLQMGTNKFASQQGMTAYGTRRHLYDPKLGTDQPLDQAT-ISLQMGTNKGASQAGMTAPG 223
Query: 178 TQRFINDVSTGVEMSDEGKQTIGLQMGPDKSQVDSQSGMS-FGAQRHITD 324
T+R I + G+E D + LQMG +K SQ GM+ +G R + D
Sbjct: 224 TKRQIFEPGLGMEHCD--TLNVSLQMGSNKGA--SQRGMTVYGLPRQVYD 269
Score = 47.4 bits (111), Expect = 1e-05
Identities = 32/73 (43%), Positives = 45/73 (61%), Gaps = 2/73 (2%)
Frame = +1
Query: 106 EGKTVIGLQAGSNKGATQAGM-RIGTQRFINDVSTGVEMSDEGKQTIGLQMGPDKSQVDS 282
EG+ +IGLQ G+NK A+Q GM GT+R + D G + + + TI LQMG +K S
Sbjct: 159 EGRNIIGLQMGTNKFASQQGMTAYGTRRHLYDPKLGTDQPLD-QATISLQMGTNKGA--S 215
Query: 283 QSGMSF-GAQRHI 318
Q+GM+ G +R I
Sbjct: 216 QAGMTAPGTKRQI 228
>sp|P51911|CNN1_HUMAN Calponin-1 (Calponin H1, smooth muscle) (Basic calponin)
Length = 297
Score = 63.9 bits (154), Expect = 1e-10
Identities = 48/110 (43%), Positives = 63/110 (57%), Gaps = 3/110 (2%)
Frame = +1
Query: 4 GLQAGSNKGASQSGM-RIGTQRFINDVSTGVEMSDEGKTVIGLQAGSNKGATQAGMRI-G 177
GLQ G+NK ASQ GM GT+R + D G + + T I LQ G+NKGA+QAGM G
Sbjct: 165 GLQMGTNKFASQQGMTAYGTRRHLYDPKLGTDQPLDQAT-ISLQMGTNKGASQAGMTAPG 223
Query: 178 TQRFINDVSTGVEMSDEGKQTIGLQMGPDKSQVDSQSGMS-FGAQRHITD 324
T+R I + G+E D + LQMG +K SQ GM+ +G R + D
Sbjct: 224 TKRQIFEPGLGMEHCD--TLNVSLQMGSNKGA--SQRGMTVYGLPRQVYD 269
Score = 47.4 bits (111), Expect = 1e-05
Identities = 32/73 (43%), Positives = 45/73 (61%), Gaps = 2/73 (2%)
Frame = +1
Query: 106 EGKTVIGLQAGSNKGATQAGM-RIGTQRFINDVSTGVEMSDEGKQTIGLQMGPDKSQVDS 282
EG+ +IGLQ G+NK A+Q GM GT+R + D G + + + TI LQMG +K S
Sbjct: 159 EGRNIIGLQMGTNKFASQQGMTAYGTRRHLYDPKLGTDQPLD-QATISLQMGTNKGA--S 215
Query: 283 QSGMSF-GAQRHI 318
Q+GM+ G +R I
Sbjct: 216 QAGMTAPGTKRQI 228
>sp|Q08091|CNN1_MOUSE Calponin-1 (Calponin H1, smooth muscle) (Basic calponin)
Length = 297
Score = 63.9 bits (154), Expect = 1e-10
Identities = 48/110 (43%), Positives = 63/110 (57%), Gaps = 3/110 (2%)
Frame = +1
Query: 4 GLQAGSNKGASQSGM-RIGTQRFINDVSTGVEMSDEGKTVIGLQAGSNKGATQAGMRI-G 177
GLQ G+NK ASQ GM GT+R + D G + + T I LQ G+NKGA+QAGM G
Sbjct: 165 GLQMGTNKFASQQGMTAYGTRRHLYDPKLGTDQPLDQAT-ISLQMGTNKGASQAGMTAPG 223
Query: 178 TQRFINDVSTGVEMSDEGKQTIGLQMGPDKSQVDSQSGMS-FGAQRHITD 324
T+R I + G+E D + LQMG +K SQ GM+ +G R + D
Sbjct: 224 TKRQIFEPGLGMEHCD--TLNVSLQMGSNKGA--SQRGMTVYGLPRQVYD 269
Score = 47.4 bits (111), Expect = 1e-05
Identities = 32/73 (43%), Positives = 45/73 (61%), Gaps = 2/73 (2%)
Frame = +1
Query: 106 EGKTVIGLQAGSNKGATQAGM-RIGTQRFINDVSTGVEMSDEGKQTIGLQMGPDKSQVDS 282
EG+ +IGLQ G+NK A+Q GM GT+R + D G + + + TI LQMG +K S
Sbjct: 159 EGRNIIGLQMGTNKFASQQGMTAYGTRRHLYDPKLGTDQPLD-QATISLQMGTNKGA--S 215
Query: 283 QSGMSF-GAQRHI 318
Q+GM+ G +R I
Sbjct: 216 QAGMTAPGTKRQI 228
>sp|Q08094|CNN2_PIG Calponin-2 (Calponin H2, smooth muscle) (Neutral calponin)
Length = 296
Score = 62.0 bits (149), Expect = 5e-10
Identities = 46/109 (42%), Positives = 60/109 (55%), Gaps = 2/109 (1%)
Frame = +1
Query: 4 GLQAGSNKGASQSGM-RIGTQRFINDVSTGVEMSDEGKTVIGLQAGSNKGATQAGMRI-G 177
GLQ G+NK ASQSGM GT+R + D + + + I LQ G+NK A+Q GM G
Sbjct: 167 GLQMGTNKCASQSGMTAYGTRRHLYDPKNHI-LPPMDHSTISLQMGTNKCASQVGMTAPG 225
Query: 178 TQRFINDVSTGVEMSDEGKQTIGLQMGPDKSQVDSQSGMSFGAQRHITD 324
T+R I D G + D ++ LQMG +Q +QSG FG R I D
Sbjct: 226 TRRHIYDTKLGTDKCD--NSSMSLQMG--YTQGANQSGQVFGLGRQIYD 270
Score = 48.5 bits (114), Expect = 6e-06
Identities = 39/104 (37%), Positives = 56/104 (53%), Gaps = 14/104 (13%)
Frame = +1
Query: 58 TQRFINDVSTGVEMSDE------------GKTVIGLQAGSNKGATQAGM-RIGTQRFIND 198
T+ +DV GV+ S++ G+ VIGLQ G+NK A+Q+GM GT+R + D
Sbjct: 133 TKGLQSDVDIGVKYSEKQQRNFDDATMKAGQCVIGLQMGTNKCASQSGMTAYGTRRHLYD 192
Query: 199 VSTGVEMSDEGKQTIGLQMGPDKSQVDSQSGMSF-GAQRHITDS 327
+ + TI LQMG +K SQ GM+ G +RHI D+
Sbjct: 193 PKNHI-LPPMDHSTISLQMGTNKCA--SQVGMTAPGTRRHIYDT 233
>sp|Q99439|CNN2_HUMAN Calponin-2 (Calponin H2, smooth muscle) (Neutral calponin)
Length = 309
Score = 48.1 bits (113), Expect = 7e-06
Identities = 41/110 (37%), Positives = 59/110 (53%), Gaps = 2/110 (1%)
Frame = +1
Query: 4 GLQAGSNKGASQSGMRIGTQRFINDVSTGVEMSDEGKTVIGLQAGSNKGATQAGM-RIGT 180
GLQ+G + G S + +R +D + G+ VIGLQ G+NK A+Q+GM GT
Sbjct: 135 GLQSGVDIGVKYSEKQ---ERNFDDATMKA-----GQCVIGLQMGTNKCASQSGMTAYGT 186
Query: 181 QRFINDVSTGVEMSDEGKQTIGLQMGPDKSQVDSQSGMSF-GAQRHITDS 327
+R + D + + TI LQMG +K SQ GM+ G +RHI D+
Sbjct: 187 RRHLYDPKNHI-LPPMDHSTISLQMGTNKCA--SQVGMTAPGTRRHIYDT 233
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 51,371,766
Number of Sequences: 369166
Number of extensions: 1002608
Number of successful extensions: 2331
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 2071
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 2285
length of database: 68,354,980
effective HSP length: 99
effective length of database: 50,066,215
effective search space used: 2002648600
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)